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Search of human proteins with 48255877
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
(295 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 582 e-166
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 551 e-157
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 546 e-156
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 536 e-153
gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] 318 3e-87
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 318 3e-87
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens] 308 4e-84
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 303 1e-82
gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] 301 6e-82
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 300 8e-82
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 292 2e-79
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 79 6e-15
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 77 1e-14
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 77 1e-14
gi|148746195 trichohyalin [Homo sapiens] 77 1e-14
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 77 2e-14
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 76 3e-14
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 76 4e-14
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 75 5e-14
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 75 7e-14
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 74 2e-13
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 72 4e-13
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 72 4e-13
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 72 6e-13
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 72 6e-13
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 71 1e-12
gi|50726968 microfibrillar-associated protein 1 [Homo sapiens] 71 1e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 69 5e-12
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 69 6e-12
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 68 8e-12
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 582 bits (1501), Expect = e-166
Identities = 295/295 (100%), Positives = 295/295 (100%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF
Sbjct: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED
Sbjct: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
Query: 181 EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKA 240
EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKA
Sbjct: 181 EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKA 240
Query: 241 KELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 295
KELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK
Sbjct: 241 KELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 295
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 551 bits (1421), Expect = e-157
Identities = 285/295 (96%), Positives = 285/295 (96%), Gaps = 10/295 (3%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
MSDIEEVVEEYEEEEQEEAAVEE QEEAAEEDAEAEAETEETRAEEDEEEE
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEE----------QEEAAEEDAEAEAETEETRAEEDEEEE 50
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF
Sbjct: 51 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 110
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED
Sbjct: 111 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 170
Query: 181 EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKA 240
EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKA
Sbjct: 171 EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKA 230
Query: 241 KELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 295
KELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK
Sbjct: 231 KELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 285
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 546 bits (1407), Expect = e-156
Identities = 285/298 (95%), Positives = 285/298 (95%), Gaps = 13/298 (4%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
MSDIEEVVEEYEEEEQEEAAVEE QEEAAEEDAEAEAETEETRAEEDEEEE
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEE----------QEEAAEEDAEAEAETEETRAEEDEEEE 50
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF
Sbjct: 51 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 110
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED
Sbjct: 111 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 170
Query: 181 EARKKKALSNMMHFGGYIQK---TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLR 237
EARKKKALSNMMHFGGYIQK TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLR
Sbjct: 171 EARKKKALSNMMHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLR 230
Query: 238 EKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 295
EKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK
Sbjct: 231 EKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 288
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 536 bits (1381), Expect = e-153
Identities = 280/297 (94%), Positives = 280/297 (94%), Gaps = 17/297 (5%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
MSDIEEVVEEYEEEEQEE QEEAAEEDAEAEAETEETRAEEDEEEE
Sbjct: 1 MSDIEEVVEEYEEEEQEE---------------QEEAAEEDAEAEAETEETRAEEDEEEE 45
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF
Sbjct: 46 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 105
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED
Sbjct: 106 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 165
Query: 181 EARKKKALSNMMHFGGYIQK--TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE 238
EARKKKALSNMMHFGGYIQK TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE
Sbjct: 166 EARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE 225
Query: 239 KAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 295
KAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK
Sbjct: 226 KAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 282
>gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens]
Length = 251
Score = 318 bits (816), Expect = 3e-87
Identities = 165/252 (65%), Positives = 201/252 (79%), Gaps = 4/252 (1%)
Query: 46 AETEETRAEEDEEEEEAKEAEDGPMEESKPKP-RSFMPNLVPPKIPDGERVDFDDIHRKR 104
++TEE EE++ EEEA E E+ EE +PKP R +P L+PPKIP+GERVDFDDIHRKR
Sbjct: 2 SDTEEQEYEEEQPEEEAAEEEEE--EEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKR 59
Query: 105 MEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAE 164
MEKDL ELQ LI+ HFE RKKEEEELV+LK+RIERRR+ERAEQQR R E+E+ERQ +LAE
Sbjct: 60 MEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAE 119
Query: 165 ERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKTERKSGKRQTEREKKKKILAERR 223
E+ R+EEEE +++AED+A+KKK LSNM HFGGY+ K E+K GKRQT RE K +IL+ER+
Sbjct: 120 EKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERK 179
Query: 224 KVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSK 283
K L ID++ E+QLREKA+EL I+ LE+EKFDL K KQQKYEINVL NRI+ QK K
Sbjct: 180 KPLDIDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRK 239
Query: 284 TRGKAKVTGRWK 295
GK +V GRWK
Sbjct: 240 GAGKGRVGGRWK 251
Score = 35.4 bits (80), Expect = 0.060
Identities = 30/139 (21%), Positives = 64/139 (46%), Gaps = 7/139 (5%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDG 68
E+ ++EE+E A++E + R E +++ + E E + + + +EEEEAK+ +
Sbjct: 76 EQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAED 135
Query: 69 PMEESKPKPR---SFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKK 125
++ K F LV + G+R R+ + L+E + ++ + ++
Sbjct: 136 DAKKKKVLSNMGAHFGGYLVKAEQKRGKR----QTGREMKVRILSERKKPLDIDYMGEEQ 191
Query: 126 EEEELVSLKDRIERRRAER 144
E+ L D I + +E+
Sbjct: 192 LREKAQELSDWIHQLESEK 210
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 318 bits (816), Expect = 3e-87
Identities = 177/297 (59%), Positives = 211/297 (71%), Gaps = 37/297 (12%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
MSD EE +EYEEE+ EE A EEEE+ A E+ E AE EE R
Sbjct: 1 MSDTEE--QEYEEEQPEEEAAEEEEE-----------APEEPEPVAEPEEER-------- 39
Query: 61 EAKEAEDGPMEESKPKP-RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
PKP R +P L+PPKIP+GERVDFDDIHRKRMEKDL ELQ LI+ H
Sbjct: 40 --------------PKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVH 85
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
FE RKKEEEELV+LK+RIERRR+ERAEQQR R E+E+ERQ +LAEE+ R+EEEE +++AE
Sbjct: 86 FEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAE 145
Query: 180 DEARKKKALSNM-MHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE 238
D+A+KKK LSNM HFGGY+ K E+K GKRQT RE K +IL+ER+K L ID++ E+QLRE
Sbjct: 146 DDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRE 205
Query: 239 KAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 295
KA+EL I+ LE+EKFDL K KQQKYEINVL NRI+ QK K GK +V GRWK
Sbjct: 206 KAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 262
>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
Length = 278
Score = 308 bits (789), Expect = 4e-84
Identities = 177/313 (56%), Positives = 211/313 (67%), Gaps = 53/313 (16%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
MSD EE +EYEEE+ EE A EEEE+ A E+ E AE EE R
Sbjct: 1 MSDTEE--QEYEEEQPEEEAAEEEEE-----------APEEPEPVAEPEEER-------- 39
Query: 61 EAKEAEDGPMEESKPKP-RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
PKP R +P L+PPKIP+GERVDFDDIHRKRMEKDL ELQ LI+ H
Sbjct: 40 --------------PKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVH 85
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
FE RKKEEEELV+LK+RIERRR+ERAEQQR R E+E+ERQ +LAEE+ R+EEEE +++AE
Sbjct: 86 FEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAE 145
Query: 180 DEARKKKALSNM-MHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQL-- 236
D+A+KKK LSNM HFGGY+ K E+K GKRQT RE K +IL+ER+K L ID++ E+QL
Sbjct: 146 DDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRA 205
Query: 237 --------------REKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVS 282
REKA+EL I+ LE+EKFDL K KQQKYEINVL NRI+ QK
Sbjct: 206 RSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFR 265
Query: 283 KTRGKAKVTGRWK 295
K GK +V GRWK
Sbjct: 266 KGAGKGRVGGRWK 278
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 303 bits (776), Expect = 1e-82
Identities = 162/268 (60%), Positives = 203/268 (75%), Gaps = 16/268 (5%)
Query: 32 DEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPD 91
DE+ E EE E EE A+E+EE +E ED EE KP+P+ L PKIP+
Sbjct: 3 DEEVEQVEEQYE-----EEEEAQEEEEVQEDTAEEDA--EEEKPRPK-----LTAPKIPE 50
Query: 92 GERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIR 151
GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR
Sbjct: 51 GEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIR 110
Query: 152 NEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKTERKSGKRQT 210
E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ K ++K GK+QT
Sbjct: 111 AEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQT 170
Query: 211 EREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINV 270
RE KKKILAERRK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I
Sbjct: 171 AREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITT 230
Query: 271 LRNRINDNQKVSKTRG---KAKVTGRWK 295
LR+RI+ QK SK G K KV GRWK
Sbjct: 231 LRSRIDQAQKHSKKAGTPAKGKVGGRWK 258
>gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]
Length = 256
Score = 301 bits (770), Expect = 6e-82
Identities = 161/268 (60%), Positives = 199/268 (74%), Gaps = 18/268 (6%)
Query: 32 DEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPD 91
DE+ E EE E E E +E AE EE E +E KPR P L PKIP+
Sbjct: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEE-----------KPR---PKLTAPKIPE 48
Query: 92 GERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIR 151
GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR
Sbjct: 49 GEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIR 108
Query: 152 NEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKTERKSGKRQT 210
E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ K ++K GK+QT
Sbjct: 109 AEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQT 168
Query: 211 EREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINV 270
RE KKKILAERRK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I
Sbjct: 169 AREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITT 228
Query: 271 LRNRINDNQKVSKTRG---KAKVTGRWK 295
LR+RI+ QK SK G K KV GRWK
Sbjct: 229 LRSRIDQAQKHSKKAGTPAKGKVGGRWK 256
Score = 32.7 bits (73), Expect = 0.39
Identities = 17/71 (23%), Positives = 35/71 (49%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAK 63
I+ E ++EE+E A++E + R E +++ + E E + + EEE+AK
Sbjct: 73 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAK 132
Query: 64 EAEDGPMEESK 74
+ +++ K
Sbjct: 133 RRAEDDLKKKK 143
Score = 32.0 bits (71), Expect = 0.67
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWR--EDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
EE+V E E+ A E++ R ++ + Q AEE A E E + RAE+D ++++A
Sbjct: 85 EELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKA 144
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 300 bits (769), Expect = 8e-82
Identities = 155/254 (61%), Positives = 197/254 (77%), Gaps = 9/254 (3%)
Query: 46 AETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRM 105
++ E + EE EEEE + E+ EE KP+P+ L PKIP+GE+VDFDDI +KR
Sbjct: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPK-----LTAPKIPEGEKVDFDDIQKKRQ 56
Query: 106 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 165
KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQNRLAEE
Sbjct: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
Query: 166 RARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKTERKSGKRQTEREKKKKILAERRK 224
+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ K ++K GK+QT RE KKKILAERRK
Sbjct: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 176
Query: 225 VLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKT 284
L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I LR+RI+ QK SK
Sbjct: 177 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 236
Query: 285 RG---KAKVTGRWK 295
G K KV GRWK
Sbjct: 237 AGTPAKGKVGGRWK 250
Score = 32.7 bits (73), Expect = 0.39
Identities = 17/71 (23%), Positives = 35/71 (49%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAK 63
I+ E ++EE+E A++E + R E +++ + E E + + EEE+AK
Sbjct: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAK 126
Query: 64 EAEDGPMEESK 74
+ +++ K
Sbjct: 127 RRAEDDLKKKK 137
Score = 32.0 bits (71), Expect = 0.67
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWR--EDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
EE+V E E+ A E++ R ++ + Q AEE A E E + RAE+D ++++A
Sbjct: 79 EELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKA 138
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 292 bits (748), Expect = 2e-79
Identities = 152/254 (59%), Positives = 194/254 (76%), Gaps = 9/254 (3%)
Query: 46 AETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRM 105
++ E + EE EEEE + E+ EE KP+P+ L PKIP+GE+VDFDDI +KR
Sbjct: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPK-----LTAPKIPEGEKVDFDDIQKKRQ 56
Query: 106 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 165
KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQNRLAEE
Sbjct: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
Query: 166 RARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKTERKSGKRQTEREKKKKILAERRK 224
+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ K ++K GK+QT RE KKKILAERRK
Sbjct: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 176
Query: 225 VLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKT 284
L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I +R R+ K SK
Sbjct: 177 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIMNVRARVQMLAKFSKK 236
Query: 285 RG---KAKVTGRWK 295
G K KV GRWK
Sbjct: 237 AGTPAKGKVGGRWK 250
Score = 32.7 bits (73), Expect = 0.39
Identities = 17/71 (23%), Positives = 35/71 (49%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAK 63
I+ E ++EE+E A++E + R E +++ + E E + + EEE+AK
Sbjct: 67 IDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAK 126
Query: 64 EAEDGPMEESK 74
+ +++ K
Sbjct: 127 RRAEDDLKKKK 137
Score = 32.0 bits (71), Expect = 0.67
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWR--EDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
EE+V E E+ A E++ R ++ + Q AEE A E E + RAE+D ++++A
Sbjct: 79 EELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKA 138
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 78.6 bits (192), Expect = 6e-15
Identities = 74/299 (24%), Positives = 143/299 (47%), Gaps = 33/299 (11%)
Query: 5 EEVVEEYEE--EEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDE---EE 59
EE ++E+EE +EQEE E+EE R EQEE E E EE ++E E+
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIR----EQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 422
Query: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEK-----DLNELQA 114
EE ++ M E + K R + K+ + E++ + R+ EK E +A
Sbjct: 423 EEKMRRQEEMMWEKEEKIRE-----LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477
Query: 115 LIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRL--AEERARREEE 172
+ E +++EE++ ++++ R+ + EQ++IR E +++ Q + EE+ R +EE
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 537
Query: 173 ENRRKA---EDEARKKKALSNMMHFGGYIQKTERKSGKRQTE--------REKKKKILAE 221
R+K E E + +K M + E K +++ + RE+++KI +
Sbjct: 538 IWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQ 597
Query: 222 RRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
K+ + + ++Q EK E + + E + + +EK ++Q+ +I +I + ++
Sbjct: 598 EEKIREQEEMTQEQ-EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Score = 73.2 bits (178), Expect = 3e-13
Identities = 55/270 (20%), Positives = 129/270 (47%), Gaps = 19/270 (7%)
Query: 5 EEVVEEYEEEEQEEAAVEEEED--------WREDED--EQEEAAEEDAEAEAETEETRAE 54
+E + E EE+ QEE + E+E WR++E EQEE E E EE E
Sbjct: 450 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE 509
Query: 55 EDE--EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNEL 112
+++ EEE+ +E E+ +E K + + + E++ + R E+ +++
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ 569
Query: 113 QALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREK---ERQNRLAEERARR 169
+ I E ++EE++ +++I + + EQ+ + E+E+ E++ ++ E+ +
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 629
Query: 170 EEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAID 229
+E+E + + ++E +++ ++ E + + E+++K+ + K+
Sbjct: 630 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM---- 685
Query: 230 HLNEDQLREKAKELWQSIYNLEAEKFDLQE 259
E+++R + +++W+ L ++ +QE
Sbjct: 686 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
Score = 71.2 bits (173), Expect = 1e-12
Identities = 67/272 (24%), Positives = 132/272 (48%), Gaps = 33/272 (12%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAE--EDAEAEAETEETRAEEDE--- 57
++EE + E E+ ++E +EEE RE E QE+ A+ E E EE E++E
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 58 -EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALI 116
+EE+ E E EE + + KI + E + R ++ ++E + I
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQ--EEKIREQEEI-------WRQKEKIHEQEEKI 552
Query: 117 EAHFENRKKEEEELVSLKDRI-ERRRAERAEQQRIRNEREKERQNRLAEERARREEEENR 175
E ++EE++ +++I E+ ++++IR + EK R+ EE+ R +EE +
Sbjct: 553 RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQ---EEKIREQEEMTQ 609
Query: 176 RKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTE--REKKKKILAERRKVLAIDHLNE 233
+ E +++ + +Q+ E K +RQ E RE++KKI + K+ E
Sbjct: 610 EQEEKMGEQEEKMCEQEE---KMQEQEEKM-RRQEEKIREQEKKIREQEEKI----REQE 661
Query: 234 DQLREKAKELWQSIYNLEAEKFDLQEKFKQQK 265
+ ++E+ +++W+ E + + +EK ++Q+
Sbjct: 662 EMMQEQEEKMWEQ----EEKMCEQEEKMQEQE 689
Score = 70.1 bits (170), Expect = 2e-12
Identities = 59/269 (21%), Positives = 133/269 (49%), Gaps = 25/269 (9%)
Query: 18 EAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEE--EEEAKEAEDGPMEESKP 75
+A VEE E W +QEE E E EE E++E+ E+E K E +E K
Sbjct: 343 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE----QEEKM 398
Query: 76 KPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKD 135
+ + M K+ E + ++ + R ++++ + E + +E EE + ++
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK-------EEKIRELEEKMHEQE 451
Query: 136 RIERRRAERAEQQRIRNEREKERQNRLA---EERARREEEENRRKAEDEARKKKALSNMM 192
+I + +R E+++IR + +++ Q EE+ R +EE+ R + E R+++ +
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQE 511
Query: 193 HFGGYIQKTERKSGKRQTER-EKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLE 251
++ E++ RQ E+ ++++I ++ K+ H E+++R++ +++W+ E
Sbjct: 512 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI----HEQEEKIRKQEEKMWRQ----E 563
Query: 252 AEKFDLQEKFKQQKYEINVLRNRINDNQK 280
+ D +EK ++Q+ ++ +I + ++
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Score = 58.5 bits (140), Expect = 7e-09
Identities = 41/175 (23%), Positives = 87/175 (49%), Gaps = 20/175 (11%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDED--EQEEAAEEDAEAEAETEETRAEEDE---EEEEAK 63
EE +++E+ +EE+ WR++E EQEE E E E EE E++E E+EE
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 622
Query: 64 EAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENR 123
++ M+E + K R E++ + + E+ + E + +++ E
Sbjct: 623 CEQEEKMQEQEEKMRR-----------QEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
Query: 124 KKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKA 178
++EE++ +++++ E+ E+ R + E+ E++ RL ++ + +E + +A
Sbjct: 672 WEQEEKMCEQEEKMQ----EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 57.4 bits (137), Expect = 1e-08
Identities = 40/192 (20%), Positives = 91/192 (47%), Gaps = 17/192 (8%)
Query: 5 EEVVEEYEE---------EEQEEAAVEEEEDWREDE---DEQEEAAEEDAEAEAETEETR 52
EE + E EE E++E+ +EE+ WR++E D++E+ E++ + + E+ R
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 53 AEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNEL 112
E EE+ +E + EE + M E++ + +R E+ + E
Sbjct: 589 --EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646
Query: 113 QALIEAHFENRKKEEEELVSLKDRI---ERRRAERAEQQRIRNEREKERQNRLAEERARR 169
+ I E +++EE + ++++ E + E+ E+ + + E+ + ++ ++ E+ R
Sbjct: 647 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 706
Query: 170 EEEENRRKAEDE 181
++E + + E
Sbjct: 707 RQQEEKMQEHQE 718
Score = 57.0 bits (136), Expect = 2e-08
Identities = 60/298 (20%), Positives = 140/298 (46%), Gaps = 25/298 (8%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDG 68
+ Y EE +E E +R + EE E++A+ + + + +E+ E + KE
Sbjct: 253 DRYIEELTKERDALSLELYRNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNVKE---- 307
Query: 69 PMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRK-RMEKDLNEL-QALIEAHFENRKKE 126
++ + + +P D + + K + + + NEL L + E ++
Sbjct: 308 -LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 366
Query: 127 EEELVSLKDRIERRRAE-RAEQQRIRNEREKERQNRLA----EERARREEE------ENR 175
EE++ +++I+ + + R ++++IR + EK R+ EE+ RR+EE E
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 176 RKAED----EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHL 231
R+ E+ + K + L MH I++ E K + + RE++K+ E + + +
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 232 NE--DQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 287
E +++RE+ +++W+ + ++ +E+ +Q++ E+ +I + +++ + + K
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Score = 50.4 bits (119), Expect = 2e-06
Identities = 60/299 (20%), Positives = 134/299 (44%), Gaps = 24/299 (8%)
Query: 13 EEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEE 72
E EQ +AV ++ + D +E E DA + T +E+ +E+ AK E + E
Sbjct: 237 ELEQALSAVATQKK-KADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVE 295
Query: 73 SKPKPRSFMPNLVPPKIPDGERV---DFDDIHRKRMEKDLNELQALIEAHFENRK----- 124
S+ + K+ + + + K+L + A ++A E +
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 355
Query: 125 --KEEEELVSLKDRIERRRAERAEQQ-RIRNEREKERQNRLAEERARREEEENRRKAEDE 181
++EE++ +++I+ + EQ+ +IR + EK R+ EE+ RR+EE K E
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ---EEKMRRQEEMMWEKEEKM 412
Query: 182 ARKKKAL----SNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLR 237
R+++ + M + + E K + + + +++KI + K + + E + R
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 472
Query: 238 -EKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 295
E+ ++W+ E + + +EK ++Q+ ++ +I++ +K+ + + + W+
Sbjct: 473 QEQEAKMWRQ----EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR 527
Score = 36.6 bits (83), Expect = 0.027
Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 4/62 (6%)
Query: 5 EEVVEEYEEE--EQEEAAVEEEEDWREDEDEQEEAAEE--DAEAEAETEETRAEEDEEEE 60
EE+++E EE+ EQEE E+EE +E E++ E+ + E +E + +E +E
Sbjct: 661 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Query: 61 EA 62
EA
Sbjct: 721 EA 722
Score = 31.6 bits (70), Expect = 0.87
Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 7/70 (10%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDED--EQEEAAEEDAEAEAETEETRAEED----E 57
I E E+ E+E E +EE+ W ++E EQEE +E E EE E++ +
Sbjct: 650 IREQEEKIREQE-EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 708
Query: 58 EEEEAKEAED 67
+EE+ +E ++
Sbjct: 709 QEEKMQEHQE 718
Score = 30.8 bits (68), Expect = 1.5
Identities = 26/143 (18%), Positives = 66/143 (46%), Gaps = 12/143 (8%)
Query: 138 ERRRAERAEQQRIRNEREKERQN-------RLAEERARREEEENRRKAEDEARKK-KALS 189
+ ++A Q+ +R E E + + + A + ++ E EAR L
Sbjct: 170 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 229
Query: 190 NMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAID----HLNEDQLREKAKELWQ 245
+ F G +++ ++ + ++ + L + R L+++ + +++L+EK +L +
Sbjct: 230 DSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE 289
Query: 246 SIYNLEAEKFDLQEKFKQQKYEI 268
+ +E+EK ++Q K+ K ++
Sbjct: 290 KLQLVESEKSEIQLNVKELKRKL 312
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 77.4 bits (189), Expect = 1e-14
Identities = 65/263 (24%), Positives = 122/263 (46%), Gaps = 32/263 (12%)
Query: 28 REDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPP 87
RE E ++E E + E E E R +E+++ K+ E G E K K R
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER--------- 82
Query: 88 KIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQ 147
+ +R + + R++ +K+ + + E +KK+E + ++R ++R ER +
Sbjct: 83 ---EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE---RERENKQRRERKRK 136
Query: 148 QRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGK 207
+R + +R KER+ +ER +RE + +RK E+ R+KK N ++ ER+ K
Sbjct: 137 KRRKKKRRKERKRE--KERGKRERKRKKRKKEE--REKKRERNRKERKKERERKERRERK 192
Query: 208 RQTEREKKKKILAERRKVLAIDHLNEDQ----LREKAKE-------LWQSIYNLEAEKFD 256
++ ++E++KK ER+K D + Q LRE A I++ + F
Sbjct: 193 KERKKERRKK--KERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRIFHTGLDHFP 250
Query: 257 LQEKFKQQKYEINVLRNRINDNQ 279
++ ++E+N +ND +
Sbjct: 251 IKTNILLSRHEVNDGEIEVNDGE 273
Score = 60.8 bits (146), Expect = 1e-09
Identities = 48/183 (26%), Positives = 91/183 (49%), Gaps = 26/183 (14%)
Query: 117 EAHFENRKKEEEELVSLKDRIERRRAERA-EQQRIRNEREKERQNRLAEERARREEEENR 175
E R+KE + K++ +R++ ER E++R R EREK+R+ R +ER +R++E+ +
Sbjct: 44 EKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKK 103
Query: 176 RKAEDEARKKKALSNMMHFGGYIQKTERK----SGKRQTEREKKKKILAERRKVLAID-- 229
R+ + R+++ +K ERK K++ ER++KK+ +RRK +
Sbjct: 104 RERKQRGRRERK-----------KKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Query: 230 --------HLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKV 281
+ + REK +E + E E+ + +E+ K++K E + R D +
Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212
Query: 282 SKT 284
+T
Sbjct: 213 RQT 215
Score = 52.0 bits (123), Expect = 6e-07
Identities = 34/169 (20%), Positives = 79/169 (46%), Gaps = 4/169 (2%)
Query: 12 EEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPME 71
E E+E+ E E++ + + ++E+ + E E E R E +++ +E +E E +
Sbjct: 39 ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
Query: 72 ESKPK----PRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEE 127
+ K K R + + ER + RKR ++ + + + E K+E
Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158
Query: 128 EELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRR 176
+ K+ E++R ++++ ER++ R+ + ++ RR+++E ++
Sbjct: 159 KRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 1/145 (0%)
Query: 149 RIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKR 208
++ E + + +++ +RE E + + E E RK++ G +K +RK +R
Sbjct: 12 KLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRER 71
Query: 209 QTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEI 268
ERE+K+K ++RK + + +K +E Q +K + +E+ ++ K
Sbjct: 72 GKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRR 131
Query: 269 NVLRNRINDNQKVSKTRGKAKVTGR 293
R + +K K R + K G+
Sbjct: 132 ERKRKK-RRKKKRRKERKREKERGK 155
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/148 (27%), Positives = 72/148 (48%), Gaps = 15/148 (10%)
Query: 152 NEREKERQNRLAEERARREEEENRR---KAEDEARKKKALSNMMHFGGYIQKTERKSGKR 208
+ER+KER+ R E+R R E+E +R K E + RKK+ ++ ERK +R
Sbjct: 34 SERKKERRER--EKRKREREKERKRERGKKEKKKRKKRERG---------KERERKRKER 82
Query: 209 QTER-EKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYE 267
+ +R E+++K +R+K + RE+ K+ + E ++ +++ K++K +
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
Query: 268 INVLRNRINDNQKVSKTRGKAKVTGRWK 295
R R + K + R K K R K
Sbjct: 143 RRKERKREKERGKRERKRKKRKKEEREK 170
Score = 35.0 bits (79), Expect = 0.079
Identities = 40/190 (21%), Positives = 75/190 (39%), Gaps = 44/190 (23%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDG 68
E+ + E ++ E ++ E E+E + + + ++ R +E + E+E + E
Sbjct: 100 EKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE-- 157
Query: 69 PMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEE 128
RKR ++ E + E + + RKKE E
Sbjct: 158 ---------------------------------RKRKKRKKEEREKKRERNRKERKKERE 184
Query: 129 ELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE----RARREEEENRRKAEDEARK 184
K+R ER++ ER +++R + ER+K+R+ + R RE NR R
Sbjct: 185 R----KERRERKK-ERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRY 239
Query: 185 KKALSNMMHF 194
+ + + HF
Sbjct: 240 RIFHTGLDHF 249
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 77.4 bits (189), Expect = 1e-14
Identities = 69/287 (24%), Positives = 138/287 (48%), Gaps = 35/287 (12%)
Query: 5 EEVVEEYEE--EEQEEAAVEEEEDWREDED---EQEEAAEEDAEAEAETEETRAEEDE-- 57
EE ++E EE +EQEE E+EE R E+ E+EE E E EE E +E
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 58 -EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALI 116
E+E+ +E E+ EE K + + E++ + + E+ + E + +
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 117 EAHFENRKKEEEELVSLKDRIERRRAE-RAEQQRIRNEREKER-QNRLAEERARREEEEN 174
E ++EEE+ ++++ R+ + R ++++IR + EK R Q + +E+ + E+
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 175 RRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTE--REKKKKILAERRKVLAIDHLN 232
+ E EA+ +Q+ E K +RQ E RE++KKI + K+
Sbjct: 474 GKMCEQEAK--------------MQEQEEKM-RRQEEKIREQEKKIREQEEKI----REQ 514
Query: 233 EDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQ 279
E+ ++E+ +++W+ E + + +EK ++Q+ ++ ++ + +
Sbjct: 515 EEMMQEQEEKMWEQ----EEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Score = 68.6 bits (166), Expect = 6e-12
Identities = 55/251 (21%), Positives = 126/251 (50%), Gaps = 33/251 (13%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDED---EQEEAAEEDAEAEAETEETRAEEDE 57
M + EE + E EE+ E+ + E+E+ R++E+ EQE+ E++A+ + E+ R +E++
Sbjct: 339 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 398
Query: 58 --EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQAL 115
E+EE + ++ M E + K E + + +R E+ + E +
Sbjct: 399 IREQEEMMQEQEEKMGEQEEK-----------MWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Query: 116 IEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENR 175
I E +++EE + ++++ + + EQ+ E+E++ + +E RE+E+
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR---QEEKIREQEKKI 504
Query: 176 RKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTER-EKKKKILAERRKVLAIDHLNED 234
R+ E++ R+++ + +Q+ E K +++ + E+++K+ + K+ E+
Sbjct: 505 REQEEKIREQEEM---------MQEQEEKMWEQEEKMCEQEEKMQEQEEKM----RRQEE 551
Query: 235 QLREKAKELWQ 245
++RE+ L Q
Sbjct: 552 KMREQEVRLRQ 562
Score = 58.5 bits (140), Expect = 7e-09
Identities = 62/285 (21%), Positives = 118/285 (41%), Gaps = 67/285 (23%)
Query: 18 EAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP 77
+A VEE E W +QEE E E EE E++E+ E +E
Sbjct: 270 QAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEK------------ 317
Query: 78 RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI 137
+R E+ + E + E +++EE + +++I
Sbjct: 318 ------------------------MRRQEEMMWEKE-------EKMRRQEEMMWEKEEKI 346
Query: 138 ERRRAERAEQQRIRNEREKERQNRLAEERARREE--------EENRRKAEDEARKKKAL- 188
+ EQ++IR + EK ++ E+ +R+E EE R+ E++ R+++ +
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406
Query: 189 -----------SNMMHFGGYIQKTERKSGKRQTE--REKKKKILAERRKVLAIDHLNEDQ 235
M +Q+ E K +RQ E RE++KKI + K+ + + ++Q
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKM-RRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 236 LREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
EK E + EA+ + +EK ++Q+ +I +I + ++
Sbjct: 466 -EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Score = 56.2 bits (134), Expect = 3e-08
Identities = 45/179 (25%), Positives = 91/179 (50%), Gaps = 23/179 (12%)
Query: 1 MSDIEEVVEEYEE---EEQEEAAVEEEEDWREDED--EQEEAAEEDAEAEAETEETRAEE 55
M + EE + E EE E++EE +EE+ R++E EQE+ E E E EE E+
Sbjct: 406 MQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 56 DEE--EEEAKEAE-DGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNEL 112
+E+ E+E K E + M+E + K R E++ + + E+ + E
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRR-----------QEEKIREQEKKIREQEEKIREQ 514
Query: 113 QALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREE 171
+ +++ E ++EE++ +++++ E+ E+ R + E+ +E++ RL ++ + +E
Sbjct: 515 EEMMQEQEEKMWEQEEKMCEQEEKMQ----EQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 32.7 bits (73), Expect = 0.39
Identities = 27/143 (18%), Positives = 67/143 (46%), Gaps = 12/143 (8%)
Query: 138 ERRRAERAEQQRIRNEREKERQN-------RLAEERARREEEENRRKAEDEARKK-KALS 189
+ ++A Q+ +R E E + Q + + A + ++ E EAR L
Sbjct: 97 DEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 156
Query: 190 NMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAID----HLNEDQLREKAKELWQ 245
+ F G +++ ++ + ++ + L + R L+++ + +++L+EK +L +
Sbjct: 157 DSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE 216
Query: 246 SIYNLEAEKFDLQEKFKQQKYEI 268
+ +E+EK ++Q K+ K ++
Sbjct: 217 KLQLVESEKSEIQLNVKELKRKL 239
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 77.4 bits (189), Expect = 1e-14
Identities = 74/308 (24%), Positives = 140/308 (45%), Gaps = 50/308 (16%)
Query: 5 EEVVEEYEEEEQEEAAV----EEEEDW--REDEDEQEEAAEEDAEAEAETEETRAE---- 54
EE E+ E+E+ E + EE DW RE+E E+ E + + + EE R E
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 55 -EDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQ 113
E+EE E +E + + + + R R + +++ LQ
Sbjct: 491 LEEEERREQQERREQQLRREQEERRE---------------------QRLKRQEEEERLQ 529
Query: 114 ALIEAHFENRKKEEEELVSLKDRIERRRAER-AEQQRIRNEREKERQNRLAEERARREEE 172
+ + + R+++EE L R E +R E+ +QR++ E+E+ R L E RR++
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ- 588
Query: 173 ENRRKAEDEARKKKALSNMMHFGGYIQKTER-KSGKRQTEREKKKKILAERRKVLAIDHL 231
R K E E R ++ L ++ ER + +R+ +R K+++ ERR+ L
Sbjct: 589 --RLKREQEERLEQRLKR--------EEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 232 NED----QLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 287
E+ QLR + +E + E E+ L+++ K++ E + + Q+ ++ R K
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK 698
Query: 288 AKVTGRWK 295
+++ +W+
Sbjct: 699 SRIP-KWQ 705
Score = 76.3 bits (186), Expect = 3e-14
Identities = 74/306 (24%), Positives = 133/306 (43%), Gaps = 59/306 (19%)
Query: 5 EEVVEEYEEEEQ---EEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDE---- 57
+E +Y EEEQ EE + EE + E+E +D + + + E+ EE E
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Query: 58 --------EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDL 109
EEEE ++ E+ + E + K R R +++ +RK+ E
Sbjct: 984 QEREKKYREEEELQQEEEQLLREEREKRR---------------RQEWERQYRKKDELQQ 1028
Query: 110 NELQALIEAHFENRKKE-------------EEELVSLKDRIERRRAE------------R 144
E Q L E + R +E EEE + ++R RRR E +
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088
Query: 145 AEQQRIRNEREK----ERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQK 200
E+Q +R E EK ER+ + EE ++EEE + E E R+++ L +Q+
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
Query: 201 TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEK 260
E + + + E+ +++++ + R+ + E LRE+ ++ Q E+ +LQ +
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 261 FKQQKY 266
++Q+Y
Sbjct: 1209 KRKQRY 1214
Score = 74.7 bits (182), Expect = 9e-14
Identities = 65/270 (24%), Positives = 127/270 (47%), Gaps = 19/270 (7%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
++++ E+ EE+E+ ++E E E+EE +E+ + E ETR ++ E +
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERE---RQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 63 KEAEDGPMEES--KPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
KE E EE + +P + + E + ++ R E++ Q L +
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
E + ++EE L++ E+RR + E+Q RE+E + E+ R E+E+ R++ E
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQY----REEEELQQEEEQLLREEQEKRRQERER 1197
Query: 181 EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKK-----KKILAERRKVLAIDHLNEDQ 235
+ R+++ L Y + +R K Q E EK+ K+ + R+ L + Q
Sbjct: 1198 QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ 1257
Query: 236 LREKAKELWQSIYNLEAEKFDLQEKFKQQK 265
LR++ + Q + +L E+ QE+ ++Q+
Sbjct: 1258 LRDRQSQ--QDLQHLLGEQ---QERDREQE 1282
Score = 72.4 bits (176), Expect = 4e-13
Identities = 78/291 (26%), Positives = 134/291 (46%), Gaps = 49/291 (16%)
Query: 5 EEVVEEYEE---EEQEEAAVEE-EEDWR-EDEDEQEEAAEEDAEAEAETEETRAEEDEEE 59
EE+ +E E+ EE+E+ +E E +R +DE +QEE E E + R + EE
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
EE ++ E+ + E + R R + + +RK E E Q L E
Sbjct: 1054 EELQQEEEQLLGEERETRR---------------RQELERQYRKEEELQQEEEQLLREEP 1098
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRL----AEERARREEEENR 175
+ R++E E + E ++ E+Q +R EREK R+ L EE ++EEE
Sbjct: 1099 EKRRRQERE-----RQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Query: 176 RKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQ 235
+ E E R+++ L Y ++ E + + Q RE+++K ER + + E++
Sbjct: 1154 LREEPEKRRRQELERQ-----YREEEELQQEEEQLLREEQEKRRQERER----QYREEEE 1204
Query: 236 L-REKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTR 285
L R+K K+ Y E ++ DL+ +++ +K N + DN+ K R
Sbjct: 1205 LQRQKRKQR----YRDEDQRSDLKWQWEPEK------ENAVRDNKVYCKGR 1245
Score = 70.9 bits (172), Expect = 1e-12
Identities = 68/275 (24%), Positives = 126/275 (45%), Gaps = 28/275 (10%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
E + E +++E+ + EEE E E + + E + E + EE + + E ++ +E
Sbjct: 795 ERQLRAEERQQREQRFLPEEE---EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE 851
Query: 65 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK 124
EDG ++E + + RS + R ++ RKR L AL E + ++
Sbjct: 852 EEDG-LQEDQERRRS-----QEQRRDQKWRWQLEE-ERKRRRHTLYAKPALQEQLRKEQQ 904
Query: 125 --KEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEA 182
+EEEE + ++R +RRR E+ Q R + ++E + L EER +R +E R +
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER----QY 960
Query: 183 RKKKALSNMMHFGGYIQKTERKSGKRQTER---EKKKKILAERRKVLAIDHLNEDQLREK 239
RK K L QK E+ G+ +R E++KK E + L ++ ++
Sbjct: 961 RKDKKLQ---------QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 240 AKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNR 274
++ W+ Y + E +E+ +++ E L+ R
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Score = 70.5 bits (171), Expect = 2e-12
Identities = 62/273 (22%), Positives = 125/273 (45%), Gaps = 42/273 (15%)
Query: 5 EEVVEEYEEE-----EQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEE 59
E++++E EE+ E++ +EEE R E EQ+ D + + EE +E EE+
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ--LRHDRDRKFREEEQLLQEGEEQ 1682
Query: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
+ ++ D E + + R ++R K L E Q L
Sbjct: 1683 QLRRQERDRKFREEEQQLR----------------------RQERERKFLQEEQQLRRQE 1720
Query: 120 FENRKKEEEELVSLKDRIERRRAER----AEQQRIRNEREKERQNRLAEERARREEEENR 175
E + +EEE+L ++ + RR ER E++++R ERE+++ R +R REEE+ R
Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLR 1780
Query: 176 RKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQ 235
++ E++ + + +++ + R +R+ K + E+ ++ E +
Sbjct: 1781 QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL----EEQEQR 1836
Query: 236 LREKAKELWQSIYNLEAEKFDLQEKFKQQKYEI 268
LR++ +++ E+F QEK ++++ E+
Sbjct: 1837 LRQERDRQYRA-----EEQFATQEKSRREEQEL 1864
Score = 68.9 bits (167), Expect = 5e-12
Identities = 59/240 (24%), Positives = 113/240 (47%), Gaps = 16/240 (6%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDED--EQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
E + E EE+ +++ +E+ + R DE+ Q + +E E AE E+ ++ + E EE
Sbjct: 145 ERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 63 KEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFEN 122
+ E E R + +RV F + K K L+ E E
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRV-FQEEEEKEWRKRETVLRKEEEKLQEE 263
Query: 123 RKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEA 182
+ + EL ++++ R+ ER E +R R E E+++Q E++ RR++EE RR+ ++E
Sbjct: 264 EPQRQRELQEEEEQL--RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 183 RKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKE 242
R+++ Q+ ER+ + + E+E++++ R + + E QLR + +E
Sbjct: 322 REQQERRE--------QQEERREQQLRREQEERREQQLRREQE---EERREQQLRREQEE 370
Score = 68.6 bits (166), Expect = 6e-12
Identities = 57/265 (21%), Positives = 126/265 (47%), Gaps = 30/265 (11%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDED----EQEEAAEEDAEAEAETEETRAEEDEEEE 60
EE ++ E + EEE++WR+ E E+E+ EE+ + + E +E EEE
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE-------EEE 276
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
+ ++ E + + + +R+ + R++ E++ E Q
Sbjct: 277 QLRKLERQELRRERQEEEQ-----------QQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
E R+++EE + ++ R + ER EQQ +R E+E+ER+ E++ RRE+EE RR+ +
Sbjct: 326 ERREQQEERR---EQQLRREQEERREQQ-LRREQEEERR----EQQLRREQEEERREQQL 377
Query: 181 EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKA 240
++ + +++ ++ ++Q RE++ + + R+ + E++ E+
Sbjct: 378 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
Query: 241 KELWQSIYNLEAEKFDLQEKFKQQK 265
E + L+ E+ + ++ K+++
Sbjct: 438 HEQERREQRLKREQEERRDWLKREE 462
Score = 68.6 bits (166), Expect = 6e-12
Identities = 62/269 (23%), Positives = 119/269 (44%), Gaps = 23/269 (8%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
EE E+ EE +++ E++E+ RE + +E+ + + E EE R E+ E+ +E
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 65 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRK----RMEKDLNELQALIEAHF 120
+ + + R ++ +++ + R+ R E+ L Q L
Sbjct: 372 RREQQLRREQQLRRE-------QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENR----- 175
R++EEE R E++ + +QR++ E+E+ R EE R E+E R
Sbjct: 425 LRREQEEE-------RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477
Query: 176 RKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQ 235
R E+E R++ ++ E++ + Q ER +++ E + L +E Q
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
Query: 236 LREKAKELWQSIYNLEAEKFDLQEKFKQQ 264
LR + +E + + E EK QE+ +Q+
Sbjct: 538 LRREQEERREQLLKREEEKRLEQERREQR 566
Score = 68.6 bits (166), Expect = 6e-12
Identities = 61/268 (22%), Positives = 122/268 (45%), Gaps = 27/268 (10%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
+ + E EE+EQ E E + +E+E+ + + + EE +ED+E ++E
Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Query: 65 AEDGP-----MEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
+EE + + R + P + + R + + + E E +
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTL--YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQE 925
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
E + +EEE+L ++++ R E+ +Q + K+++ + EE+ EE E RR+ E
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 180 DEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREK 239
R+KK Y ++ E + + Q RE+++K RR+ + +D+L+++
Sbjct: 986 ---REKK----------YREEEELQQEEEQLLREEREK---RRRQEWERQYRKKDELQQE 1029
Query: 240 AKELWQSIYNLEAEKFDLQEKFKQQKYE 267
++L + E EK LQE+ +Q + E
Sbjct: 1030 EEQLLRE----EREKRRLQERERQYREE 1053
Score = 68.2 bits (165), Expect = 8e-12
Identities = 69/305 (22%), Positives = 144/305 (47%), Gaps = 47/305 (15%)
Query: 5 EEVVEEYEEEEQEEAAVEEEE----------DWREDEDEQEEAAEEDAEAEAETEETRAE 54
EE ++E E + Q E EEE+ R++E++Q++ + + + EE R E
Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERRE 316
Query: 55 EDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQA 114
+ EE E +E + E + + R ++ R+ E++ E Q
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQL------------RREQEEERREQQL 364
Query: 115 LIEAHFENRKKE--EEELVSLKDRIERRRAERAEQQ-----RIRNEREKERQNRLA-EER 166
E E R+++ E+ + + ++ R + R EQQ ++R E++ R+ +L E++
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 167 ARREEEENR--RKAEDEARKKKALSNMMHFGGYIQKTE------RKSGKRQTEREKKKKI 218
RRE+EE R +K E E R+++ ++++ E ++ K+Q +R++++
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE-- 482
Query: 219 LAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDN 278
ERR+ L E++ RE+ + Q + + E+ +++ K+Q+ E L+ R+
Sbjct: 483 --ERRERWL--KLEEEERREQQERREQQLRREQEER--REQRLKRQEEE-ERLQQRLRSE 535
Query: 279 QKVSK 283
Q++ +
Sbjct: 536 QQLRR 540
Score = 65.5 bits (158), Expect = 5e-11
Identities = 67/281 (23%), Positives = 125/281 (44%), Gaps = 37/281 (13%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEE-A 62
+EE ++E +E+ E+E+ RE +++E E + ++ R E++E E+
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 63 KEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFEN 122
K E+ +E+ + + R K ER D + ++ E+ L+ E E
Sbjct: 551 KREEEKRLEQERREQRL--------KREQEER--RDQLLKREEERRQQRLKREQEERLEQ 600
Query: 123 RKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEA 182
R K EE +R+E+ ER EQ+ R E E+ER+ +L + + E + + + E +
Sbjct: 601 RLKREE-----VERLEQE--ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 183 RKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKE 242
R+++ L ++ + KR+ E E++++ LAE ++Q RE+ K
Sbjct: 654 RREQRLKREEE-----EERLEQRLKREHEEERREQELAEE---------EQEQARERIKS 699
Query: 243 ---LWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
WQ + LE+E Q K + + R R +K
Sbjct: 700 RIPKWQ--WQLESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
Score = 65.1 bits (157), Expect = 7e-11
Identities = 71/301 (23%), Positives = 139/301 (46%), Gaps = 32/301 (10%)
Query: 12 EEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE-AEDGPM 70
EE E++ E + +RE+E +E E+ + + R EE +E+ ++ E+
Sbjct: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQR 1382
Query: 71 EESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL 130
+ + R F+ + + E+ D RK E++ Q L + + +EEE+
Sbjct: 1383 LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE----QQLSRQERDRKFREEEQQ 1438
Query: 131 VSLKDRI------------ERRRAERAEQQRI--RNEREKERQNR----LAEERARREEE 172
V ++R ER R R E+Q + R E++ RQ R L EE+ R +E
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQE 1498
Query: 173 ENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTERE-KKKKILAERRKVLAIDHL 231
+R+ E E R ++ + + + +R+ Q E++ ++++ +RR+
Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
Query: 232 NEDQLREKAKELWQSIYNLEAE-KFDLQE-KFKQQKYEINVLRNRINDNQKVSKTRGKAK 289
E+QLR++ +E Q + E + KF L+E K ++Q+ E R + D Q++ + G+ +
Sbjct: 1559 EEEQLRQEREE--QQLSRQERDRKFRLEEQKVRRQEQE----RKFMEDEQQLRRQEGQQQ 1612
Query: 290 V 290
+
Sbjct: 1613 L 1613
Score = 64.7 bits (156), Expect = 9e-11
Identities = 65/271 (23%), Positives = 130/271 (47%), Gaps = 32/271 (11%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAA---EEDAEAEAETEETRAEEDEEEEE 61
E+ ++ EEEE+ + + E+ R +++E+ E EE+ E E E R + ++EE
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 62 ---AKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEA 118
K E+ + K + + + K + ER++ ++ +R++++ E E
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRL--KREEVERLEQEERREQRLKREEPE-----EE 628
Query: 119 HFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKA 178
+ K EE+ + ++ R + ER E QR++ E E+ER E+R +RE EE RR+
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERRE-QRLKREEEEER----LEQRLKREHEEERREQ 683
Query: 179 E--DEARKKKALSNMMHFGGYIQKTERKSGKRQTE-REKKKKILAERRKVLAIDHLNEDQ 235
E +E +++ + + E ++ RQ++ + +K +RR+ E++
Sbjct: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR-----QEQEEK 738
Query: 236 LREKAKEL-WQSIYNLEAEKFDLQEKFKQQK 265
R + EL WQ E E+ Q++ ++Q+
Sbjct: 739 RRRRESELQWQ-----EEERAHRQQQEEEQR 764
Score = 64.7 bits (156), Expect = 9e-11
Identities = 70/292 (23%), Positives = 141/292 (48%), Gaps = 29/292 (9%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAK 63
+EE + + ++ Q + EE++ R++ +Q +D + + EE +E EE++ ++
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR---RQDRDRKFREEEQLRQEREEQQLSR 1574
Query: 64 EAEDGP--MEESK----PKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIE 117
+ D +EE K + R FM + + +G++ + ++R K + Q L E
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ----QLRQERDRKFREDEQLLQE 1630
Query: 118 AHFENRKKEEEELVSLKDRIERRRAERAEQ---QRIRNEREKERQNRLAEERARREEEEN 174
+ ++E + L++ + RR ER +Q R R RE+E+ + EE+ R +E +
Sbjct: 1631 REEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
Query: 175 RRKAEDE------ARKKKALSNMMHFGGYIQKTERK-SGKRQTEREKKKKILAERRKVLA 227
R+ E+E R++K L Q+ ERK + Q +E +++ L + +
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRR--QELERKFREEEQLRQETEQEQLRRQERYRK 1748
Query: 228 IDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQ 279
I L E+QLR + +E Q + E ++ +E+ +Q+ E LR++ +D +
Sbjct: 1749 I--LEEEQLRPEREE--QQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Score = 60.5 bits (145), Expect = 2e-09
Identities = 55/243 (22%), Positives = 105/243 (43%), Gaps = 34/243 (13%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
+++ EE E+ E EQ + +EE WR+ ++ QE EE RAEE++ +
Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQER------------EERRAEEEQLQS 195
Query: 61 -EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
+ E E+ P EE R + ++ RK E+ + + +
Sbjct: 196 CKGHETEEFPDEEQL------------------RRRELLELRRKGREEKQQQRRERQDRV 237
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
F+ +++E R E + + E QR R +E+E Q R E + R E + + +
Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297
Query: 180 DEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREK 239
R+++ L Q+ ER+ + + E++++++ RR+ + E QLR +
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ---EERREQQLRRE 354
Query: 240 AKE 242
+E
Sbjct: 355 QEE 357
Score = 60.5 bits (145), Expect = 2e-09
Identities = 73/319 (22%), Positives = 143/319 (44%), Gaps = 67/319 (21%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDE---EE 59
++E E EE +QEE + EE + E E E+ E + E E+ EE E +E
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Query: 60 EEAKEAEDGPMEESKPKPR--------------------SFMPNLVPPKIPDGER---VD 96
E + E+ ++ K K R + N V K + E+ ++
Sbjct: 1195 RERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLE 1254
Query: 97 FDDIHRKRMEKDLNELQALIEAHFENRKKE------------EEELVSLKDRIERRRAER 144
+ ++ ++DL L L E +R++E EEE + +++ E +R +R
Sbjct: 1255 DSQLRDRQSQQDLQHL--LGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Query: 145 ---AEQQRIRNEREKERQNRLAEERAR--------REEEENRRKAEDEARKKKALSNMMH 193
E+Q +R ERE++R+ + + + R REE+ RR+ D +++ L +
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQ 1372
Query: 194 FGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE----KAKELWQSIYN 249
++++ +R +RQ E+++K L E +++ + E QLR+ K +E Q +
Sbjct: 1373 GRKFLEEEQRL--RRQ---ERERKFLKEEQQLRCQE--REQQLRQDRDRKFREEEQQLSR 1425
Query: 250 LEAEKFDLQEKFKQQKYEI 268
E ++ KF++++ ++
Sbjct: 1426 QERDR-----KFREEEQQV 1439
Score = 59.7 bits (143), Expect = 3e-09
Identities = 58/284 (20%), Positives = 131/284 (46%), Gaps = 28/284 (9%)
Query: 2 SDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEA-----EAETEETRAEED 56
S+++ EE +Q+E + W+ +E+ E + A E + RAEE
Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803
Query: 57 EEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALI 116
++ E+ E+ E+ + + R L + + E + + R+ + L E + +
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKEL---QFLEEE----EQLQRRERAQQLQEEEDGL 856
Query: 117 EAHFENRKKEEEE-----LVSLKDRIERRR----AERAEQQRIRNEREKERQNRLAEERA 167
+ E R+ +E+ L++ +RRR A+ A Q+++R E++ ++ EE
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE---EEEL 913
Query: 168 RREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLA 227
+REE E RR+ E E + ++ +++ K +++ ER+ +K ++++
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973
Query: 228 IDHLNEDQLREKAKELWQSIYNLEAEKFDL----QEKFKQQKYE 267
+ E + R++ ++ ++ L+ E+ L +EK ++Q++E
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017
Score = 59.3 bits (142), Expect = 4e-09
Identities = 58/275 (21%), Positives = 117/275 (42%), Gaps = 39/275 (14%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDED-----EQEEAAEEDAEAEAETEETRAEEDEEE 59
+E ++ +EEQ+ E E+ R+D D E+++ + ++ + + EE + E E
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445
Query: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
+ E E +E K R L + + +HR+ ++ E + +
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLL--------QEREEQQLHRQERDRKFLEEEQQLRRQ 1497
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNR----LAEERARREEEENR 175
+RK E+EL R++ E++ + E++ RQ R L EE+ R +E +
Sbjct: 1498 ERDRKFREQEL----------RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547
Query: 176 RKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDH---LN 232
++ +D RK F Q + + ++ + +E+ +K E +KV +
Sbjct: 1548 QRRQDRDRK---------FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFM 1598
Query: 233 EDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYE 267
ED+ + + +E Q + KF E+ Q++ E
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE 1633
Score = 58.2 bits (139), Expect = 9e-09
Identities = 53/221 (23%), Positives = 98/221 (44%), Gaps = 16/221 (7%)
Query: 6 EVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEED-----EEEE 60
E ++ +E+E ++EE+ R E E++ EE E E E+ R +E EEE+
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDL----NELQALI 116
E E+ + + + R F + + +++ + RK E++ E Q L
Sbjct: 1755 LRPEREEQQLRRQE-RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR 1813
Query: 117 EAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRR 176
+ + + EEE + L+++ +R R ER Q R + + ++R E+ +EEE+ RR
Sbjct: 1814 PQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRR 1873
Query: 177 K------AEDEARKKKALSNMMHFGGYIQKTERKSGKRQTE 211
+ E+ R+++ G I+ E K R E
Sbjct: 1874 QERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLE 1914
Score = 57.4 bits (137), Expect = 1e-08
Identities = 58/284 (20%), Positives = 129/284 (45%), Gaps = 30/284 (10%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDE----EEEEAKE 64
+E +E E +EEE+ + +++ EE E + R ++ + EEE+ ++
Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Query: 65 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK 124
+ + + R F + + ER +D + R ++ +L+ + F
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF---- 1621
Query: 125 KEEEELVSLKDRIERRRAER-----AEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
+E+E+L+ ++ + R ER E+ ++R + E+E+Q R +R REEE+ ++ E
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ-EREQQLRHDRDRKFREEEQLLQEGE 1680
Query: 180 DEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAE----RRKVLAIDHLNEDQ 235
++ +++ R+ ++ +E+++K L E RR+ L E+Q
Sbjct: 1681 EQQLRRQERDRKF----------REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Query: 236 LREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQ 279
LR++ ++ + + E + L+E+ + + E LR + D +
Sbjct: 1731 LRQETEQ--EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Score = 57.4 bits (137), Expect = 1e-08
Identities = 53/249 (21%), Positives = 110/249 (44%), Gaps = 14/249 (5%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDE---EEE 60
+EE + +E +++ + + +RE+E +E E+ + + R EE + +E
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDL----NELQALI 116
E K ++ + R F + + E++ + +RK +E++ E Q L
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 117 EAHFENRKKEEEELVSLKDRIERRRAER----AEQQRIRNEREKERQNRLAEERARREEE 172
+ + +EEE+L ++ + R E E++++R ERE+++ + R EE
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825
Query: 173 ENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTE--REKKKKILAERRKVLAIDH 230
E + E E R ++ T+ KS + + E +E+++K ER + L +H
Sbjct: 1826 EQLQLEEQEQRLRQERDRQYRAEEQF-ATQEKSRREEQELWQEEEQKRRQERERKLREEH 1884
Query: 231 LNEDQLREK 239
+ Q E+
Sbjct: 1885 IRRQQKEEQ 1893
Score = 56.2 bits (134), Expect = 3e-08
Identities = 73/288 (25%), Positives = 135/288 (46%), Gaps = 45/288 (15%)
Query: 6 EVVEEYEEEEQEEAAVEEEEDWRE------DEDEQEEAAEEDAEAEAETEETRAEEDEEE 59
E VE E+EE+ E ++ EE E +EQEE ++ + E +E R + + E
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ--QLRREQQERREQRLKRE 662
Query: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
EE + E E + + R ++ + E+ + R+R++ + + Q +E+
Sbjct: 663 EEEERLEQRLKREHEEERRE-------QELAEEEQ----EQARERIKSRIPKWQWQLESE 711
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARR--EEEENRR- 176
+ R+ + V + R + + R EQ+ R RE E Q + EERA R +EEE RR
Sbjct: 712 ADARQSK----VYSRPRKQEGQRRRQEQEEKRRRRESELQWQ-EEERAHRQQQEEEQRRD 766
Query: 177 -----KAEDEA-RKKKALSNMMHFGGYIQKTERKSGKRQ---------TEREKKKKILAE 221
+AE+++ R ++ LS ++ R ++Q E+E++++ E
Sbjct: 767 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE 826
Query: 222 RRKVLA-IDHLNEDQLREKAKELWQSIYNL--EAEKFDLQEKFKQQKY 266
R K L ++ + Q RE+A++L + L + E+ QE+ + QK+
Sbjct: 827 REKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874
Score = 55.5 bits (132), Expect = 6e-08
Identities = 70/271 (25%), Positives = 121/271 (44%), Gaps = 43/271 (15%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEED-----EEEEEAK 63
E+ +E+ EEE+ +E E++Q E D + E ++ R +E E+E ++
Sbjct: 1452 EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511
Query: 64 EAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHR-KRMEKDLNELQALIEAHFEN 122
E E +EE + +HR +R K L E Q L
Sbjct: 1512 EPERKFLEEEQ------------------------QLHRQQRQRKFLQEEQQLRRQERGQ 1547
Query: 123 RKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEA 182
+++++ + ++ E+ R ER EQQ R ER +R+ RL E++ RR+E+E R+ EDE
Sbjct: 1548 QRRQDRDRKFREE--EQLRQEREEQQLSRQER--DRKFRLEEQKVRRQEQE-RKFMEDEQ 1602
Query: 183 RKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAER-RKVLAIDHLNEDQLREKAK 241
+ ++ + R+ + ERE+++ ER RK L E QLR + +
Sbjct: 1603 QLRRQ-EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE----EEPQLRRQER 1657
Query: 242 ELWQSIYNLEAEKFDLQEKFKQQKYEINVLR 272
E Q + + KF +E+ Q+ E + R
Sbjct: 1658 E--QQLRHDRDRKFREEEQLLQEGEEQQLRR 1686
Score = 54.7 bits (130), Expect = 1e-07
Identities = 61/264 (23%), Positives = 125/264 (47%), Gaps = 46/264 (17%)
Query: 14 EEQEEAAVEEEEDWRED---EDEQEEAAEEDAEAEAETEETRAEEDEEEE-EAKEAEDGP 69
+E++ A + +E +D E++Q D + E E + R ++ +E+E E E E+
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
Query: 70 MEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEE-- 127
++ + + R D +R D +++ R+R E E + E ++ K E
Sbjct: 156 EKQERLEQR------------DRQRRD-EELWRQRQEWQEREERRAEEEQLQSCKGHETE 202
Query: 128 ----EELVSLKDRIE-RRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEA 182
EE + ++ +E RR+ +QQ + +ERQ+R+ +E EEE+ RK E
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQ-----QRRERQDRVFQE----EEEKEWRKRETVL 253
Query: 183 RKKKALSNMMHFGGYIQKTERKSGKRQTE-REKKKKILAERRKVLAIDHLNEDQLREKAK 241
RK++ +K + + +RQ E +E+++++ R+ L + E+Q +++ +
Sbjct: 254 RKEE------------EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301
Query: 242 ELWQSIYNLEAEKFDLQEKFKQQK 265
Q E E+ + QE+ ++Q+
Sbjct: 302 REQQLRRKQEEERREQQEERREQQ 325
Score = 54.3 bits (129), Expect = 1e-07
Identities = 68/299 (22%), Positives = 126/299 (42%), Gaps = 62/299 (20%)
Query: 9 EEYEEEEQEEAA-------------VEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEE 55
+E EEEQE+A +E E D R+ + +E E EE R
Sbjct: 683 QELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Query: 56 DEEEE--EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQ 113
+ E + E + A EE + + ++ +R+ R++ E+ L
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRA-- 800
Query: 114 ALIEAHFENRKKEEEELVSLKDRIERRRAERAE--------------QQRIRNEREKERQ 159
E R++ E+ + ++ E+RR +R E Q+R R ++ +E +
Sbjct: 801 -------EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
Query: 160 NRLAEERARREEEENRRKAE-----DEARK--------KKALSNMMHFGGYIQKTERKSG 206
+ L E++ RR +E RR + +E RK K AL + + + E +
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913
Query: 207 KRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQK 265
+R+ EREK+++ ER+ + E+QL+++ ++L + E EK QE+ +Q +
Sbjct: 914 QRE-EREKRRRQEQERQ------YREEEQLQQEEEQLLRE----EREKRRRQERERQYR 961
Score = 47.4 bits (111), Expect = 2e-05
Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 30/174 (17%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAK 63
+EE E EEQ+ E + +RE+E ++E E+ ++ + R EEE+ +
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR----EEEQLRQ 1805
Query: 64 EAEDGPMEESKPKPRSFMPNLVPPKIPDGE-RVDFDDIHRKRMEKDLNELQALIEAHFEN 122
E E+ ++ +P+ R DG+ R + + + + E Q L +
Sbjct: 1806 EREE---QQLRPQQR------------DGKYRWEEEQLQLEEQE------QRLRQERDRQ 1844
Query: 123 RKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRR 176
+ EE+ K R E + + E+Q+ R ERE+ +L EE RR+++E +R
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERER----KLREEHIRRQQKEEQR 1894
Score = 39.3 bits (90), Expect = 0.004
Identities = 39/173 (22%), Positives = 79/173 (45%), Gaps = 28/173 (16%)
Query: 92 GERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI------ERRRAERA 145
G+ D+ R R + + LQ + R++E++ +DR +RRR +R
Sbjct: 90 GQATGLDEEKRARCDGKESLLQ-------DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ 142
Query: 146 EQQR--IRNEREKERQNRLAEERARREEEEN--RRKAEDEARKKKALSNMMHFGGYIQKT 201
EQ+R E + E+Q RL E+R R+ +E R++ E + R+++ ++
Sbjct: 143 EQERELAEGEEQSEKQERL-EQRDRQRRDEELWRQRQEWQEREERR----------AEEE 191
Query: 202 ERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEK 254
+ +S K E + RR++L + ++ +++ +E ++ E EK
Sbjct: 192 QLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK 244
Score = 30.8 bits (68), Expect = 1.5
Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 8/66 (12%)
Query: 5 EEVVEEYEEEEQ----EEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
+E +Y EEQ E++ EE+E W+E+E ++ + + E + E R ++ EE+
Sbjct: 1839 QERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ----ERERKLREEHIRRQQKEEQR 1894
Query: 61 EAKEAE 66
+ E
Sbjct: 1895 HRQVGE 1900
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 76.6 bits (187), Expect = 2e-14
Identities = 81/294 (27%), Positives = 136/294 (46%), Gaps = 31/294 (10%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
+IE+ E E E + E E E RE E E+E+ E + E E + + R +E + + +
Sbjct: 304 EIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDR 363
Query: 63 KEAEDGPMEES----KPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEA 118
+ D E S K + RS + + + ER + R+R + E + E
Sbjct: 364 ERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERER 423
Query: 119 HFENRKKEEEELVSLKDRIERRRAER-------AEQQRIRNEREKER-QNRLAEERARRE 170
E KK + E +D ERR+ ER A Q+R++N +ER + R E+ A RE
Sbjct: 424 EREKDKKRDRE-EDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAERE 482
Query: 171 EEENRRKAEDEARKKKALSN--------MMHFGGYIQKTERKSGKR----QTEREKKKKI 218
EE R A++ R K+ L + + G +QK R K + +R+++K+
Sbjct: 483 EERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEE 542
Query: 219 LAE-RRKVLAIDHLNED----QLREKAKELWQSIYNLEAEKFDLQEKFKQQKYE 267
L E R+++LA H + D ++ ++A+ Q E E + +E+ KQ+K E
Sbjct: 543 LEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPES-EEEEEEKQEKEE 595
Score = 75.5 bits (184), Expect = 5e-14
Identities = 70/279 (25%), Positives = 130/279 (46%), Gaps = 43/279 (15%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
+++ EE ++E+E +E+E RE E E+E E E E E E R +E E E E +
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERRE-REREREREREREKEKERERERER 347
Query: 65 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK 124
D + + + R D ER D D + +++ + ++ ++ R+
Sbjct: 348 DRDRDRTKERDRDR------------DRER-DRDRDRERSSDRNKDRSRSREKSRDRERE 394
Query: 125 KEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEEN---RRKAEDE 181
+E E ++R R ER ++ ERE+ER+ ++R R E+EE+ RRK E +
Sbjct: 395 RERE-----REREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449
Query: 182 ARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAK 241
R+K+A + ++ E + K+ E EK+ + ERR+ +A ++AK
Sbjct: 450 LREKEAA-----YQERLKNWEIRERKKTREYEKEAEREEERRREMA----------KEAK 494
Query: 242 ELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
L + + + + ++ D + Y + L+ R+ D +K
Sbjct: 495 RLKEFLEDYDDDRDD------PKYYRGSALQKRLRDREK 527
Score = 68.6 bits (166), Expect = 6e-12
Identities = 52/191 (27%), Positives = 87/191 (45%), Gaps = 25/191 (13%)
Query: 10 EYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRA---------------- 53
E E E + E E E+D + D +E EE A E + E + E A
Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKK 471
Query: 54 -EEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNEL 112
E E+E E +E M + + + F+ + D +R D ++K L +
Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLEDY------DDDRDDPKYYRGSALQKRLRDR 525
Query: 113 QALIEAHFENRKKEEEELVSLKDRI--ERRRAERAEQQRIRNEREKERQNRLAEERARRE 170
+ +EA +RK+E+EEL ++ R+ E AE QR+ E E+ RQ ++ +E E
Sbjct: 526 EKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEE 585
Query: 171 EEENRRKAEDE 181
EEE +++ E++
Sbjct: 586 EEEEKQEKEEK 596
Score = 62.0 bits (149), Expect = 6e-10
Identities = 51/228 (22%), Positives = 103/228 (45%), Gaps = 19/228 (8%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDG 68
E+ + E+E E E RE E E+E E + E E E E+ + + EE+EE
Sbjct: 386 EKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK 445
Query: 69 PMEESKPKPRSFMPNLVPPKIPDGERV-------DFDDIHRKRMEKDLNELQALIEAHFE 121
+ + K ++ L +I + ++ + ++ R+ M K+ L+ +E + +
Sbjct: 446 LERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDD 505
Query: 122 NRKKEEEELVS-----LKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRR 176
+R + S L+DR + A+ +++R + E E+ RQ LAE + E R
Sbjct: 506 DRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRM 565
Query: 177 KAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRK 224
+ E E R++ + ++E + ++Q + EK+++ + E +
Sbjct: 566 EQEAERRRQPQIKQE-------PESEEEEEEKQEKEEKREEPMEEEEE 606
Score = 61.2 bits (147), Expect = 1e-09
Identities = 70/308 (22%), Positives = 128/308 (41%), Gaps = 42/308 (13%)
Query: 8 VEEYEEEEQEEAAVEEEEDWREDEDE--QEEAAEEDAEAEAETEETRAEEDEE-EEEAKE 64
++E++ +++ E D++E EE D + E E E ++E
Sbjct: 169 LDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQE 228
Query: 65 AEDGPMEESKPKPRSFMPNL-VPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF--- 120
++ P ++ K K V P IP + +DI+ ME+D +L + + F
Sbjct: 229 SDSHPRKKKKEKKEDIFRRFPVAPLIPY-PLITKEDINAIEMEEDKRDLISREISKFRDT 287
Query: 121 ------ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEE- 173
E KKE+E K+R ER R E++R ERE+ER+ +E+ R E E
Sbjct: 288 HKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERER 347
Query: 174 --------------NRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKIL 219
+R + D R++ + N ++ KS R+ ERE++++
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRERSSDRNKDR-----SRSREKSRDRERERERERERE 402
Query: 220 AERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQ 279
ER + + E + RE+ +E E +K +E+ ++ YE L ++ + +
Sbjct: 403 RERERERERERERERE-RERERE-------REKDKKRDREEDEEDAYERRKLERKLREKE 454
Query: 280 KVSKTRGK 287
+ R K
Sbjct: 455 AAYQERLK 462
Score = 37.0 bits (84), Expect = 0.021
Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 4/79 (5%)
Query: 7 VVEEYEEEEQEEAAVEEE-EDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEA 65
+ E + + + E +E+E E R+ + +QE +EE+ E + E EE R E EEEE E
Sbjct: 551 LAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEE---EP 607
Query: 66 EDGPMEESKPKPRSFMPNL 84
E P + +P S P++
Sbjct: 608 EQKPCLKPTLRPISSAPSV 626
Score = 36.6 bits (83), Expect = 0.027
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEA----EAETEETRAEEDEE 58
+ +E + E+EE EE + D D + + E++AE + + E EE+EE
Sbjct: 530 EADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589
Query: 59 EEEAKEAEDGPMEESK 74
++E +E + PMEE +
Sbjct: 590 KQEKEEKREEPMEEEE 605
Score = 34.7 bits (78), Expect = 0.10
Identities = 20/75 (26%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
++EE+ + E + E + +E E ++ +++ E+E E EE + E++E+ EE
Sbjct: 542 ELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESE-EEEEEKQEKEEKREEP 600
Query: 63 KEAEDGPMEESKPKP 77
E E+ P ++ KP
Sbjct: 601 MEEEEEPEQKPCLKP 615
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 76.3 bits (186), Expect = 3e-14
Identities = 46/108 (42%), Positives = 59/108 (54%), Gaps = 19/108 (17%)
Query: 2 SDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAE------------TE 49
S EE EE EEEE+EE EEEED+ E+E+++EE EE+ E E E E
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944
Query: 50 ETRAEEDEEEEEAKEAED-------GPMEESKPKPRSFMPNLVPPKIP 90
E E++EEEEE +E ED G +EE P P + P L PP+ P
Sbjct: 945 EEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESP 992
Score = 41.2 bits (95), Expect = 0.001
Identities = 40/153 (26%), Positives = 60/153 (39%), Gaps = 8/153 (5%)
Query: 20 AVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 79
A+EE+ EE EE+ E E E EE EED EEEE E E+ EE + +
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE--EDEEEYFEEEEEEEEE 930
Query: 80 FMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIER 139
F + E + ++ + E++ EL+ + + F E EE +
Sbjct: 931 FEEEF------EEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPP 984
Query: 140 RRAERAEQQRIRNEREKERQNRLAEERARREEE 172
+++ E E E L E EEE
Sbjct: 985 ALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEE 1017
Score = 39.3 bits (90), Expect = 0.004
Identities = 36/136 (26%), Positives = 49/136 (36%), Gaps = 18/136 (13%)
Query: 57 EEEEEAKEAEDGPMEESKPKPRSFM-------PNLVPPKIPDGERVDFDDIHRKRMEKDL 109
+EE E A GP+ P P P LVP P G +E+DL
Sbjct: 826 KEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPP-------ALEEDL 878
Query: 110 NELQALI----EAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 165
+ E E ++EEEE ++ E + E E E+E + EE
Sbjct: 879 TVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938
Query: 166 RARREEEENRRKAEDE 181
EEEE E+E
Sbjct: 939 EGELEEEEEEEDEEEE 954
Score = 34.7 bits (78), Expect = 0.10
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 7/75 (9%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAE-- 66
+E EEE EE+ + D+ + E AE E ET ET AE +E+E+ A
Sbjct: 1051 QELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMET-ETEAEALQEKEQDDTAAML 1109
Query: 67 ----DGPMEESKPKP 77
D P ++ KP P
Sbjct: 1110 ADFIDCPPDDEKPPP 1124
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 75.9 bits (185), Expect = 4e-14
Identities = 67/278 (24%), Positives = 140/278 (50%), Gaps = 40/278 (14%)
Query: 1 MSDIEEVVEEYEEEEQE-EAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEE 59
M +EE++ E EE+ +E E + E+E RE E++++E EE + + +E A+ +E
Sbjct: 365 MRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE--EEKIREQEKRQEQEAKMWRQE 422
Query: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
E+ +E E+ E+ K R KI + E++ ++ KR E++ Q
Sbjct: 423 EKIREQEEKIREQEKKMWRQ------EEKIHEQEKIREEE---KRQEQEEMWRQ------ 467
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREK----ERQNRLAEERARREEE--- 172
E + +E+EE+ K+++ + R +++++ + EK E + R EE+ R+EE
Sbjct: 468 -EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR 526
Query: 173 ENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHL- 231
E K ++ K + MM Q+ E K G+++ + ++++K+ + K+ +
Sbjct: 527 EQEEKIREQEEKIREQEEMM------QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI 580
Query: 232 --NEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYE 267
++++RE+ +++W+ + EK QE+ Q++ E
Sbjct: 581 REQKEKIREQEEKIWE-----QEEKIREQEEMMQEQEE 613
Score = 75.5 bits (184), Expect = 5e-14
Identities = 60/273 (21%), Positives = 136/273 (49%), Gaps = 20/273 (7%)
Query: 5 EEVVEEYEEEEQEEAAVEEEED--------WREDED--EQEEAAEEDAEAEAETEETRAE 54
+E + E EE+ QEE + E+E WR++E EQEE E + EE E
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 448
Query: 55 EDE--EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNEL 112
+++ EEE+ +E E+ +E K + + + K+ + E++ + R E+ +++
Sbjct: 449 QEKIREEEKRQEQEEMWRQEEKIREQEEIWR-QKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 113 QALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREK---ERQNRLAEERARR 169
+ I E ++EE++ +++I + + EQ+ + E+E+ E++ ++ E+ R
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
Query: 170 EEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAID 229
+EE R+ E++ R++K + Q+ E+ + + +E+++K+ + K+ +
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQE-EKIREQEEMMQEQEEKMWEQEEKMCEQE 626
Query: 230 HL---NEDQLREKAKELWQSIYNLEAEKFDLQE 259
E+++R + +++W+ L ++ +QE
Sbjct: 627 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 75.1 bits (183), Expect = 7e-14
Identities = 70/293 (23%), Positives = 137/293 (46%), Gaps = 30/293 (10%)
Query: 5 EEVVEEYEE--EEQEEAAVEEEEDWREDEDE---QEEAAEEDAEAEAETEETRAEED--- 56
EE ++E+EE +EQEE E+EE RE E++ QEE E E EE E++
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 57 --------EEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKD 108
E+EE+ +E E+ E+ K + + KI + E+ + R E+
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQE-EKRQEEEKIREQEKRQEQEAKMWRQEEK 424
Query: 109 LNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERAR 168
+ E + I E + +EE + +++I + +++ R E + Q + ++ +
Sbjct: 425 IREQEEKIREQ-EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 169 REEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTE-REKKKKILAERRKVLA 227
E+E RK E++ +++ M I++ E K +++ + RE+++KI + K+
Sbjct: 484 MHEQEKIRKQEEKVWRQE--EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541
Query: 228 IDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
+ + ++Q EK E + EK QEK ++Q+ +I +I + ++
Sbjct: 542 QEEMMQEQ-EEKMGE--------QEEKMQEQEKMRRQEEKIREQEEKIREQKE 585
Score = 73.2 bits (178), Expect = 3e-13
Identities = 66/297 (22%), Positives = 140/297 (47%), Gaps = 51/297 (17%)
Query: 4 IEEVVEEYE-----EEEQEEAAVEEEE---DWREDEDEQEEAAEEDAEAEAETEETRAEE 55
++ VEE E ++QEE +EE +W E EQEE E E E EE +
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 340
Query: 56 DE---EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNEL 112
+E E+EE ++ M E + K R + + E++ + +E+ ++E
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE----EKI-------RELEEKMHEQ 389
Query: 113 QALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREK--------ERQNRLAE 164
+ + E E +++EEE++ + R E+ ++++IR + EK RQ
Sbjct: 390 EKIREQ--EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 165 ERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRK 224
E+ + EEE R++ E+ R+++ + I + + K +++ R++++K+ + K
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEE----IWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 225 VLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKV 281
+ H E+++RE+ +++W+ +EK ++Q+ +I +I + +++
Sbjct: 504 M----HDQEEKIREQEEKMWRQ-----------EEKIREQEEKIREQEEKIREQEEM 545
Score = 58.5 bits (140), Expect = 7e-09
Identities = 61/298 (20%), Positives = 140/298 (46%), Gaps = 25/298 (8%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDG 68
+ Y EE +E E +R + EE E++A+ + + + +E+ E + KE
Sbjct: 192 DRYIEELTKERDALSLELYRNTITD-EELKEKNAKLQEKLQLVESEKSEIQLNVKE---- 246
Query: 69 PMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRK-RMEKDLNEL-QALIEAHFENRKKE 126
++ + + +P D + + K + + + NEL L + E ++
Sbjct: 247 -LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 305
Query: 127 EEELVSLKDRIERRRAE-RAEQQRIRNEREKERQNRLA----EERARREEE------ENR 175
EE++ +++I+ + + R ++++IR + EK R+ EE+ RR+EE E
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 176 RKAED----EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHL 231
R+ E+ + K + L MH I++ E K + + RE++K+ E + + +
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425
Query: 232 NE--DQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 287
E +++RE+ K++W+ + ++ +E+ +Q++ E+ +I + +++ + + K
Sbjct: 426 REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Score = 55.8 bits (133), Expect = 4e-08
Identities = 42/176 (23%), Positives = 87/176 (49%), Gaps = 12/176 (6%)
Query: 5 EEVVEEYEEE--EQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
EE + + EE+ EQEE +EE RE E++ E E+ E E +E + E+EE+
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 560
Query: 63 KEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFEN 122
+E E +E K + + KI + E ++ E+ + E + +++ E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE------QEEKIREQEEMMQEQEEK 614
Query: 123 RKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKA 178
++EE++ +++++ E+ E+ R + E+ E++ RL ++ + +E + +A
Sbjct: 615 MWEQEEKMCEQEEKMQ----EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 40.4 bits (93), Expect = 0.002
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 25/132 (18%)
Query: 1 MSDIEEVVEEYEEE--------EQEEAAVEEEEDWREDED---EQEEAAEEDAEAEAETE 49
M + EE + E EE+ QEE E+EE RE ++ EQEE E E E E
Sbjct: 546 MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQE 605
Query: 50 ETRAEEDE---EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRME 106
E E++E E+EE ++ M+E + K R E++ ++ ++ E
Sbjct: 606 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR-----------QEEKMWEQEVRLRQQE 654
Query: 107 KDLNELQALIEA 118
+ + E Q +EA
Sbjct: 655 EKMQEHQEHLEA 666
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 75.5 bits (184), Expect = 5e-14
Identities = 66/295 (22%), Positives = 128/295 (43%), Gaps = 25/295 (8%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
+E E +E+ E + E++ + ++ E E + E E ETE R + + E + +
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
Query: 65 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLN---ELQALIEAHFE 121
+ E+ + R+ K + ER D R++ E++ + Q E E
Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296
Query: 122 NRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDE 181
+K E + ++R R+ ER ERE+ER+ + ER R +E E +RK + E
Sbjct: 297 TERKRERQRERERERERNRKRER------ERERERERERQRETERDREKERERKRKRQTE 350
Query: 182 ARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAK 241
+++ + + G+RQ ERE++++ +R+ + D+ R++ K
Sbjct: 351 MDRER------------NRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK 398
Query: 242 E---LWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGR 293
E + + + E +E+ K ++ E R R + QK + R + + T R
Sbjct: 399 ERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQK-GRERDRERQTDR 452
Score = 69.7 bits (169), Expect = 3e-12
Identities = 67/281 (23%), Positives = 125/281 (44%), Gaps = 20/281 (7%)
Query: 10 EYEEEEQEEAAVEEEEDWREDEDEQEEAAEE-----DAEAEAETEETRAEEDEEE---EE 61
E E E + E + + D + + + Q +A +E D E + +TE R +E E E +E
Sbjct: 128 ERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQE 187
Query: 62 AKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFE 121
+E E +E+K + R + + + ER + RKR + Q E E
Sbjct: 188 RRERERQREKENKTEDR----HSERGRERERERETETETERKRQTDRERDRQRKTERERE 243
Query: 122 NRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREE--EENRRKAE 179
+ + E +R + R ER ++ R R+ R+KER+ + +R RR E E RK E
Sbjct: 244 KQAERERASERETERDKERERER-DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 180 DEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREK 239
+ +++ ++ + +R+TER+++K+ +R++ +D Q +
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362
Query: 240 AKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
+ + E E+ D Q ++++ E R+R D QK
Sbjct: 363 GRRQAERERERERER-DRQSAREREERE----RDRDRDRQK 398
Score = 62.8 bits (151), Expect = 4e-10
Identities = 57/272 (20%), Positives = 118/272 (43%), Gaps = 22/272 (8%)
Query: 10 EYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGP 69
E +++ E E+ + RE + ++E E+D + + R + E+E E + +
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 70 MEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEE 129
+ K + R + + R D R+R E Q E E + E +
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRER------ERQRDAEKERERQTDRERQ 168
Query: 130 LVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARR-EEEENRRKAEDEARKKKAL 188
+ ++R + R E+ Q+R ER++E++N+ + + R E E R+ E E +K+
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR-- 226
Query: 189 SNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIY 248
Q + +R+TERE++K+ AER + + D+ RE+ ++ +
Sbjct: 227 ----------QTDRERDRQRKTEREREKQ--AERERA-SERETERDKERERERDRDRDRD 273
Query: 249 NLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
+ E+ ++ +Q++ E + R + Q+
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQR 305
Score = 60.5 bits (145), Expect = 2e-09
Identities = 59/275 (21%), Positives = 116/275 (42%), Gaps = 30/275 (10%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAE------EDAEAEAETEETRAEEDEEEEEA 62
E + ++E E+E R+ E E+E E + + E E R E E E +
Sbjct: 104 ERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163
Query: 63 KEAEDGPMEESKPKPRSFMPNLVPPKIPDGERV---DFDDIHRKRMEKDLNELQALIEAH 119
E ++ K R N + + +R +D H +R + E + E
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE 223
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
+ + E + +R ++AER ER+KER+ +R R ++ R +
Sbjct: 224 RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQT 283
Query: 180 DEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREK 239
D R+++ + ++TERK +RQ ERE++++ +R + ++ RE+
Sbjct: 284 DRKRQRRTERD--------RETERKR-ERQRERERERERNRKRER-----ERERERERER 329
Query: 240 AKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNR 274
+E E ++ +E+ ++++ E++ RNR
Sbjct: 330 QRE-------TERDREKERERKRKRQTEMDRERNR 357
Score = 58.5 bits (140), Expect = 7e-09
Identities = 50/218 (22%), Positives = 95/218 (43%), Gaps = 26/218 (11%)
Query: 2 SDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEE 61
+D E + E E+E+ A E RE E ++E E D + + + + E + +
Sbjct: 228 TDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKR 287
Query: 62 AKEAE-DGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
+ E D E + + R + + ER R+R + E + E
Sbjct: 288 QRRTERDRETERKRERQRERERERERNRKRERER------ERERERERQRETERDREKER 341
Query: 121 ENRKKEEEELVSLKDRIERRRAER-AEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
E ++K + E+ ++R R R AE++R ERE+ER + A ER RE + +R + +
Sbjct: 342 ERKRKRQTEMDRERNRQTGREGRRQAERER---ERERERDRQSAREREERERDRDRDRQK 398
Query: 180 DEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKK 217
+ R Q + + G+R+TE++++++
Sbjct: 399 ERER---------------QTEKDRDGQRETEKQRERE 421
Score = 58.2 bits (139), Expect = 9e-09
Identities = 55/263 (20%), Positives = 102/263 (38%), Gaps = 40/263 (15%)
Query: 30 DEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKI 89
D D++E +++ E E +T E D + E +E +
Sbjct: 50 DGDDRERNRQKERERRREKRQTERETDRKRERRREKD----------------------- 86
Query: 90 PDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQR 149
R D HR+R E + + + ++++E ++R R ER ++
Sbjct: 87 ----RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
Query: 150 IRNEREKERQNRLAEERAR-------REEEENRRKAEDEARKKKALSNMMHFGGYIQKTE 202
+RE+ERQ +ER R R+ E NR+K + + ++ KTE
Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
Query: 203 RKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFK 262
+ +R ERE++++ E + D D+ R+ +E +AE+ E+
Sbjct: 203 DRHSERGRERERERETETETERKRQTDR-ERDRQRKTERE-----REKQAERERASERET 256
Query: 263 QQKYEINVLRNRINDNQKVSKTR 285
++ E R+R D + K R
Sbjct: 257 ERDKERERERDRDRDRDRRQKER 279
Score = 57.8 bits (138), Expect = 1e-08
Identities = 46/221 (20%), Positives = 91/221 (41%), Gaps = 7/221 (3%)
Query: 12 EEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPME 71
E E + + E E D D D +++ E + + + R E E + E + + E
Sbjct: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERE 312
Query: 72 ESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELV 131
++ + R + + ER + RKR + + + + E R++ E E
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER- 371
Query: 132 SLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM 191
ER R + R R ERE++R +ER R+ E++ + E E ++++
Sbjct: 372 ------ERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
Query: 192 MHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLN 232
G + K R+ +RE++ A R++ + ++N
Sbjct: 426 SERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVN 466
Score = 49.3 bits (116), Expect = 4e-06
Identities = 46/181 (25%), Positives = 73/181 (40%), Gaps = 31/181 (17%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQE--EAAEEDAEAEAETEETRAEEDEEEE 60
+ E E E E+E + E RE E E+E E D E E E + R E + E
Sbjct: 296 ETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER 355
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
+ +G + + + R + ER R+ E+D +
Sbjct: 356 NRQTGREGRRQAERERER------------ERERDRQSAREREERERDRD---------- 393
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
+R+KE E KDR +R E+ + EREK+R++ ER R E++ R+ +
Sbjct: 394 RDRQKERERQTE-KDRDGQRETEK------QREREKDRESERGRERGREREKQKGRERDR 446
Query: 181 E 181
E
Sbjct: 447 E 447
Score = 35.8 bits (81), Expect = 0.046
Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 14/164 (8%)
Query: 142 AERAEQQRIRN-EREKERQNRLAEERARREEEENRRKAEDEARKK---------KALSNM 191
A+ +++R R ERE+ R+ R E R+ E RR+ +D RK+ +
Sbjct: 49 ADGDDRERNRQKERERRREKRQTERETDRKRE--RRREKDRHRKRDRHRERQRDREKERE 106
Query: 192 MHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLE 251
+ K RQ ERE++ + ER + D E + + A++ + + E
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166
Query: 252 AEKFDLQEKFKQQKYEIN--VLRNRINDNQKVSKTRGKAKVTGR 293
++ + + K+++ E N R R +K +KT + GR
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
Score = 35.0 bits (79), Expect = 0.079
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 139 RRRAERAEQQRIRNEREKERQNRLAEERARRE-EEENRRKAEDEARKKKALSNMMHFGGY 197
RR +A + ++RE+ RQ R +R+ E E RK E K + H
Sbjct: 39 RRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRH--RE 96
Query: 198 IQKTERKSGKRQTEREKKKKILAERRK 224
Q+ K +RQT+RE+ ++ ER +
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNR 123
Score = 31.6 bits (70), Expect = 0.87
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAA-----EEDAEAEAETEETRAEEDEEEEEAK 63
EE E + + E E +D D Q E E+D E+E E R E ++ E
Sbjct: 386 EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERD 445
Query: 64 EAEDGPMEESKPKPRSFMPNLVPPK 88
+ + + RS + PP+
Sbjct: 446 RERQTDRQAGRQRKRSTLYVNPPPR 470
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 75.1 bits (183), Expect = 7e-14
Identities = 72/296 (24%), Positives = 149/296 (50%), Gaps = 24/296 (8%)
Query: 5 EEVVEEYEEE--EQEEAAVEEEEDWREDED---EQEEAAEEDAEAEAETEETRAEED--E 57
EE++ E EE+ QEE E+EE R E+ E+EE E E E E+ R +E+ +
Sbjct: 355 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 414
Query: 58 EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIE 117
EEE+ +E E +E+K + KI + E+ + R E+ ++E + + E
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW------RQEEKIHEQEKIRE 468
Query: 118 AHFENRKKE---EEELVSLKDRIERRRAERAEQ-QRIRNEREK--ERQNRLAEERAR-RE 170
++E +EE + ++ I R++ + EQ ++IR + EK ++ ++ E+ + RE
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 171 EEENRRKAEDEARKKKAL---SNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLA 227
+EE + E++ R+++ + MH I + E++ + +++KI + KV
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR 588
Query: 228 IDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSK 283
+ +Q EK +E + ++ E + + +EK ++Q+ +I +I + +++++
Sbjct: 589 QEEKIREQ-EEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Score = 74.7 bits (182), Expect = 9e-14
Identities = 75/284 (26%), Positives = 140/284 (49%), Gaps = 49/284 (17%)
Query: 5 EEVVEEYEE--EEQEEAAVEEEEDWREDEDE---QEEAAEEDAEAEAETEETRAEEDE-- 57
EE ++E+EE +EQEE E+EE RE E++ QEE E E EE E++E
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 58 --------EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEK-- 107
E+EE ++ M E + K R + K+ + E++ + R+ EK
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRE-----LEEKMHEQEKIREQEEKRQEEEKIR 420
Query: 108 ---DLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRL-- 162
E +A + E +++EE++ + ++ R+ + EQ++IR E +++ Q +
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 163 AEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTE-REKKKKILAE 221
EE+ +EE R+K + +++K I+K E K +++ + RE+++KI +
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEK-----------IRKQEEKVWRQEEKIREQEEKIREQ 529
Query: 222 RRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQK 265
K+ E+++RE+ +E+W+ E EK QEK +++
Sbjct: 530 EEKMWR----QEEKIREQ-EEMWR-----EEEKMHEQEKIWEEE 563
Score = 69.7 bits (169), Expect = 3e-12
Identities = 65/288 (22%), Positives = 125/288 (43%), Gaps = 69/288 (23%)
Query: 4 IEEVVEEYE-----EEEQEEAAVEEEE---DWREDEDEQEEAAEEDAEAEAETEETRAEE 55
++ VEE E ++QEE +EE +W E EQEE E E E EE +
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 340
Query: 56 DE---EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNEL 112
+E E+EE ++ M E + K R R E+ + E
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMR-------------------------RQEEMMWEK 375
Query: 113 QALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEE 172
+ E +++EE + +++I + EQ++IR + EK ++ E+ +R+E+
Sbjct: 376 E-------EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 428
Query: 173 ENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLN 232
E + ++E I++ E K RE++KK+ + K+ + +
Sbjct: 429 EAKMWRQEEK---------------IREQEEKI------REQEKKMWRQEEKIHEQEKIR 467
Query: 233 EDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
E++ R++ +E+W+ + EK QE+ +QK +++ +I ++
Sbjct: 468 EEEKRQEQEEMWR-----QEEKIHEQEEIWRQKEKMHEQEEKIRKQEE 510
Score = 69.3 bits (168), Expect = 4e-12
Identities = 60/283 (21%), Positives = 130/283 (45%), Gaps = 10/283 (3%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
+E + E EE+ QEE + E+E +E E + E+ E E + E + +EE+ E
Sbjct: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE 462
Query: 65 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK 124
E EE + + KI + E + E+ + + + + E +
Sbjct: 463 QEKIREEEKRQEQEEMWRQ--EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIR 520
Query: 125 KEEEELVSLKDRIERRRAERAEQQRIRNEREK-ERQNRLAEERARREEEENRRKAEDEAR 183
++EE++ ++++ R+ + EQ+ + E EK Q ++ EE R+E+E+ + E++ R
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
Query: 184 KK-----KALSNMMHFGGYIQKTERKSGKRQTE-REKKKKILAERRKVLAIDHLNEDQLR 237
++ + + Q+ E K K++ + RE+++KI + K+ + +Q
Sbjct: 581 EQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ-E 639
Query: 238 EKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
E +E + + E + + +EK ++Q+ + +I + +K
Sbjct: 640 EMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Score = 66.6 bits (161), Expect = 2e-11
Identities = 65/275 (23%), Positives = 128/275 (46%), Gaps = 47/275 (17%)
Query: 5 EEVVEEYEE---------EEQEEAAVEEEEDWREDED--EQEEAAEEDAEAEAETEETRA 53
EE + E EE E++E+ +EE+ WR++E EQEE E E EE
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR 541
Query: 54 EEDE--EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNE 111
E++E EEE ++ EE K + + KI + E + R E+ + E
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW------RQEEKIRE 595
Query: 112 LQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQ-RIRNEREKERQNRLAEERARRE 170
+ E R+++EE++ +++I + + EQ+ +IR + EK R+ EE + +
Sbjct: 596 QE-------EKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ---EEMTQEQ 645
Query: 171 EEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDH 230
EE+ + E +++ + ++ E + + RE++KKI + K+
Sbjct: 646 EEKMGEQEEKMCEQEEKMQ---------EQEETMWRQEEKIREQEKKIREQEEKI----R 692
Query: 231 LNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQK 265
E+ ++E+ +++W+ E + + +EK ++Q+
Sbjct: 693 EQEEMMQEQEEKMWEQ----EEKMCEQEEKMQEQE 723
Score = 60.8 bits (146), Expect = 1e-09
Identities = 44/194 (22%), Positives = 102/194 (52%), Gaps = 10/194 (5%)
Query: 104 RMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRA---ERAEQQRIRNER--EKER 158
R E+ + E + I+ E +++EE++ ++++ R+ E+ E+ R + E EKE
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 159 QNRLAEERARREEEENRRKAE---DEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKK 215
+ R EE +EE+ RR+ E ++ K + L MH I++ E K + + RE++
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 216 KKILAERRKVLAIDHLNE--DQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRN 273
K+ E + + + E +++RE+ K++W+ + ++ +E+ +Q++ E+
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 483
Query: 274 RINDNQKVSKTRGK 287
+I++ +++ + + K
Sbjct: 484 KIHEQEEIWRQKEK 497
Score = 60.1 bits (144), Expect = 2e-09
Identities = 43/190 (22%), Positives = 91/190 (47%), Gaps = 20/190 (10%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDE---QEEAAEEDAEAEAETEETRAEEDE 57
M + E++ EE + +EQE+ +EE RE E++ QEE E E E EE +++E
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 58 ---EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQA 114
E+EE + ++ + E + K R E + E+ + E +
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIRE-----------QEEMTQEQEEKMGEQEEKMCEQEE 661
Query: 115 LIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREK---ERQNRLAEERARREE 171
++ E ++EE++ + +I + + EQ+ + E+E+ E++ ++ E+ + +E
Sbjct: 662 KMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721
Query: 172 EENRRKAEDE 181
+E + + ++E
Sbjct: 722 QEEKMRRQEE 731
Score = 55.5 bits (132), Expect = 6e-08
Identities = 43/173 (24%), Positives = 84/173 (48%), Gaps = 19/173 (10%)
Query: 5 EEVVEEYEE--EEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
EE + E EE +EQEE ++EE RE E++ +E E+ E E + E E+EE+
Sbjct: 590 EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 63 KEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHR-KRMEKDLNELQALIEAHFE 121
E E+ E+ + K+ + E + + + EK + E + I E
Sbjct: 650 GEQEEKMCEQEE-------------KMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Query: 122 NRKKEEEELVSLKDRI---ERRRAERAEQQRIRNEREKERQNRLAEERARREE 171
+++EE++ ++++ E + E+ E+ R + E+ E++ RL ++ + +E
Sbjct: 697 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 30.8 bits (68), Expect = 1.5
Identities = 26/143 (18%), Positives = 66/143 (46%), Gaps = 12/143 (8%)
Query: 138 ERRRAERAEQQRIRNEREKERQN-------RLAEERARREEEENRRKAEDEARKK-KALS 189
+ ++A Q+ +R E E + + + A + ++ E EAR L
Sbjct: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 168
Query: 190 NMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAID----HLNEDQLREKAKELWQ 245
+ F G +++ ++ + ++ + L + R L+++ + +++L+EK +L +
Sbjct: 169 DSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE 228
Query: 246 SIYNLEAEKFDLQEKFKQQKYEI 268
+ +E+EK ++Q K+ K ++
Sbjct: 229 KLQLVESEKSEIQLNVKELKRKL 251
Score = 30.8 bits (68), Expect = 1.5
Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 7/67 (10%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDED--EQEEAAEEDAEAEAETEETRAEED----E 57
I E E+ E+E E +EE+ W ++E EQEE +E E EE E++ +
Sbjct: 684 IREQEEKIREQE-EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Query: 58 EEEEAKE 64
+EE+ +E
Sbjct: 743 QEEKMQE 749
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 73.9 bits (180), Expect = 2e-13
Identities = 59/222 (26%), Positives = 103/222 (46%), Gaps = 25/222 (11%)
Query: 27 WREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 86
W+ + E+E E E + E E R +E E E+ K + + + K
Sbjct: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK---------- 83
Query: 87 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKE----EEELVSLKDRIERRRA 142
K GER + +KR + N+ E + KKE +E + + ER+R
Sbjct: 84 -KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKRE 142
Query: 143 ERAEQQRIRNEREKERQNRLAEERARR---EEEENRRKAEDEARKKKALSNMMHFGGYIQ 199
ER E++R + EREKER+ + ++R R+ E+EE R++ E + RKK+ + +
Sbjct: 143 ERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK-------E 195
Query: 200 KTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAK 241
+ + + K + ER+K++K ER+K D + +E+ K
Sbjct: 196 RKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237
Score = 73.2 bits (178), Expect = 3e-13
Identities = 59/229 (25%), Positives = 102/229 (44%), Gaps = 18/229 (7%)
Query: 34 QEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGE 93
Q E E + E E E + E E ++E +E E E K + R K GE
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRER-----GKKEKKGE 89
Query: 94 RVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNE 153
R + +KR + EN++ EE+E K++ ER R + ++R R E
Sbjct: 90 RKKEERERKKRRREK------------ENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137
Query: 154 REKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTERE 213
E++R+ R ER + E E+ R + E + R++K + ++ ERK +R +
Sbjct: 138 -ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 214 KKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFK 262
KK++ ERR+ E++ +E+ K+ + E K + +E+ K
Sbjct: 197 KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 70.1 bits (170), Expect = 2e-12
Identities = 59/222 (26%), Positives = 102/222 (45%), Gaps = 25/222 (11%)
Query: 6 EVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETE----ETRAEEDEEEEE 61
E+ E E E + +E E R+ E + E + + E E + E E + E +EE E
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 62 AK------EAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQAL 115
K E ++G +E + K + + ER + + +R E++ + +
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE-ERKREERKERERKKEERE 155
Query: 116 IEAHFENRKKEEEELVSLK--DRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEE 173
E + RKK E + V K +R E+ R ER +++R R ER+KER ER R E +
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER------ERKERRERK 209
Query: 174 NRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKK 215
RK ++E +K++ ++ E++ GKR+ + KK
Sbjct: 210 KERKKKEERKKERQKDRQTNW------REKERGKRERKERKK 245
Score = 64.7 bits (156), Expect = 9e-11
Identities = 50/187 (26%), Positives = 93/187 (49%), Gaps = 12/187 (6%)
Query: 106 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAER-AEQQRIRNEREK--ERQNRL 162
+ ++ E + IE E +K+ E E + E+R+ ER E++R R ++EK ER+
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 163 AEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAER 222
E + RR E+EN+ E E RKKK ++ ERK +++ ER+++++ ER
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 223 RKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVS 282
K E + +E+ K + + E E+ + +E+ +++K E N + +K
Sbjct: 155 EK--------ERERKERKKRERKQVGEKEEERKE-KERKERKKRERNRKERKKERERKER 205
Query: 283 KTRGKAK 289
+ R K +
Sbjct: 206 RERKKER 212
Score = 61.6 bits (148), Expect = 8e-10
Identities = 48/173 (27%), Positives = 81/173 (46%), Gaps = 21/173 (12%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
EE + E+E EE+E ++ E ++ ++ + EE + EE +E E KE
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 65 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK 124
+ E + K R ER + +R EK+ E + E + + RK
Sbjct: 153 EREKERERKERKKR--------------ERKQVGEKEEERKEKERKERKKR-ERNRKERK 197
Query: 125 KEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAE-ERARREEEENRR 176
KE E K+R ER++ ER +++ + ER+K+RQ E ER +RE +E ++
Sbjct: 198 KERER----KERRERKK-ERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 72.4 bits (176), Expect = 4e-13
Identities = 67/280 (23%), Positives = 140/280 (50%), Gaps = 31/280 (11%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEEDWREDED--EQEEAAEEDAEAEAETEETRAEEDEE--E 59
+E++ EE + +EQE+ ++EE +E+E E+E+ E+ E E EE +++E E
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 60 EEAKEAEDGPMEESKPK--PRSFMPNLVPP------KIPDGERVDFDDIHRKRMEKDLNE 111
+E KE + + E K K + M KI D E + + R EK + E
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK-MRE 541
Query: 112 LQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREE 171
+ + E + +E+++ ++R+E++ E+ ++ + E+ +E + E+ REE
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 172 EENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTE-REKKKKILAERRKVLAIDH 230
EE R+ E++ ++++ +Q+ E K +++ + +E+++K+ + K+ +
Sbjct: 602 EEMMREQEEKMQEQEE---------KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652
Query: 231 --LNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEI 268
+ +L E+ ++LW E EK QEK ++Q+ +I
Sbjct: 653 KMWEQQRLPEQKEKLW------EHEKMQEQEKMQEQEEKI 686
Score = 70.1 bits (170), Expect = 2e-12
Identities = 64/287 (22%), Positives = 134/287 (46%), Gaps = 28/287 (9%)
Query: 1 MSDIEEVVEEYEEE--EQEEAAVEEEEDWREDE----DEQEEAAEEDAEAEAETEETRAE 54
M + EE + E EE+ QEE E+E+ RE E D++E E+D + E R +
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 416
Query: 55 EDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQA 114
E E+ K E+ M+E + K R K+ + ER+ + + E+ + E +
Sbjct: 417 EKMWEQVEKMREEKKMQEQEKKTRD-----QEEKMQEEERIREREKKMREEEETMREQEE 471
Query: 115 LIEAHFENRKKEEEE------LVSLKDRIERRRAERAEQQRIRNEREKER--------QN 160
++ EN ++EE+ L K+++ + + ++++I + EK R +
Sbjct: 472 KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 531
Query: 161 RLAEERARREEEENRRKAEDEAR--KKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKI 218
++ + RE+E+ + E++ R ++K Q+ E+K+ Q E+ ++++
Sbjct: 532 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD-QEEKMREEER 590
Query: 219 LAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQK 265
+ ER K + + + EK +E + + E + ++ +EK ++Q+
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQE 637
Score = 69.3 bits (168), Expect = 4e-12
Identities = 67/291 (23%), Positives = 135/291 (46%), Gaps = 37/291 (12%)
Query: 3 DIEEVVEEYEEE----EQEEAAVEEEEDWREDED----------EQEEAAEEDAEAEAET 48
++ E E E+E EQEE E+EE RE E+ EQE+ E + +
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 49 EETRAEEDE--EEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRME 106
EE E+DE E+E + E M E K R K+ + E+ D + + E
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMRE------EKKMQEQEKKTRDQEEKMQEE 449
Query: 107 KDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEER 166
+ + E + + E +++EE++ ++ + + + +QQR+ ++EK L E+
Sbjct: 450 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK-----LWEQE 504
Query: 167 ARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTER---EKKKKILAERR 223
+E+EE + E++ R ++ + G +K R+ R+ E E+++K+ + +
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEM------WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 558
Query: 224 KVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNR 274
K+ + E + +E+ K+ W + E+ ++E+ K+ + E ++R +
Sbjct: 559 KMWDQEERMEKKTQEQEKKTWDQEEKMREEE-RMREREKKMREEEEMMREQ 608
Score = 68.9 bits (167), Expect = 5e-12
Identities = 69/298 (23%), Positives = 142/298 (47%), Gaps = 22/298 (7%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDED---EQEEAAEEDAEAEAETEETRAEEDE---E 58
E++ EE E+E+ EEEE RE E+ EQEE +E E E EE E++E E
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE 642
Query: 59 EEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEA 118
+EE ++ M E + P K+ + E++ + EK + Q +
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Query: 119 HFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAE-ERARREEEENRRK 177
++ K EEE S+++R E++ E E R + E+ +E++ ++ E E E+EE +
Sbjct: 703 TWDQEKMREEE--SMRER-EKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE 759
Query: 178 AEDEARKKKAL---SNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNED 234
E++ +++ L + +Q+ E+ + + R++++K+ + K+ E+
Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRG----QEE 815
Query: 235 QLREKAKELW---QSIYNLEAEKFDLQEKF--KQQKYEINVLRNRINDNQKVSKTRGK 287
++R + +++W + ++ E + + +EK +++K E + ++ K RG+
Sbjct: 816 KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ 873
Score = 66.2 bits (160), Expect = 3e-11
Identities = 60/289 (20%), Positives = 140/289 (48%), Gaps = 23/289 (7%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
M D E+ + + EE +++ +E++ W ++E +EE + E + EE E EE+
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 612
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
+ +E + EE + M K+ + E ++ + ++ L E + + H
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQE-QEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH- 670
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
+ +E+E++ +++I + E+ E++ E++ Q ++ EE + RE E+ R+ E+
Sbjct: 671 -EKMQEQEKMQEQEEKIWEQ--EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 181 EARKKKALSNMMHFGGYIQKTERKSGKRQTER-EKKKKILAERRKVLAIDHLNEDQLREK 239
R+++ +Q+ E K +++ E E+++K+ + K+ + +L E+
Sbjct: 728 MMREQEE---------KMQEQEEKMQEQEEEMWEQEEKMWEQEEKM-----WEQQRLPEQ 773
Query: 240 AKELWQSIYNLEAEK-FDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 287
++LW+ E EK ++ +EK + Q+ ++ ++ ++ K RG+
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE--KMRGQ 820
Score = 65.9 bits (159), Expect = 4e-11
Identities = 65/289 (22%), Positives = 127/289 (43%), Gaps = 52/289 (17%)
Query: 5 EEVVEEYEEE--EQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
EE + E E++ +QEE +EE RE E + E E+ E E E E+E+E
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Query: 63 KEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFEN 122
+E ++ + E+ + E + + E
Sbjct: 338 REQKE----------------------------------LREQEEQMQEQEEKMWEQEEK 363
Query: 123 RKKEEEELVSLKDRI-ERRRAERAEQQRIRNEREK--ERQNRLAEERARREEEENRRKAE 179
+++EE++ ++R+ E+ + R ++Q++R++ E+ E+ RL E+ R E+E +
Sbjct: 364 MREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQV 423
Query: 180 DEARKKKALSNMMHFGGYIQKTERKSGKRQTE---REKKKKILAE----RRKVLAIDHLN 232
++ R++K + +KT + K Q E RE++KK+ E R + +
Sbjct: 424 EKMREEKKMQEQE------KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE 477
Query: 233 EDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKV 281
E+ ++ KE Q + EK QEK ++Q+ +I +I D +++
Sbjct: 478 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526
Score = 56.6 bits (135), Expect = 3e-08
Identities = 41/185 (22%), Positives = 89/185 (48%), Gaps = 9/185 (4%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA 62
D E++ EE E+E+ EEEE RE E++ +E E+ E E E E + E+EE+
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764
Query: 63 KEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFEN 122
E + P ++ K K+ + E++ + + E+ + + + E
Sbjct: 765 WEQQRLPEQKEKLWEHE--------KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEK 816
Query: 123 RKKEEEELVSLKDRIERRRAER-AEQQRIRNEREKERQNRLAEERARREEEENRRKAEDE 181
+ +EE++ ++++ + + +++++ + EK + +E RE+EE R E++
Sbjct: 817 MRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEK 876
Query: 182 ARKKK 186
R+++
Sbjct: 877 MREQE 881
Score = 52.8 bits (125), Expect = 4e-07
Identities = 56/266 (21%), Positives = 122/266 (45%), Gaps = 15/266 (5%)
Query: 28 REDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPP 87
+ D +E E DA + T E+ +++ A+ E P+ ES+ +
Sbjct: 194 KADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKR 253
Query: 88 KIPDGE----RVDFDDIHRK--RMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR 141
K+ + +V + + + R E++L E + I E ++EE L + ++ +
Sbjct: 254 KLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE 313
Query: 142 AERAEQQRIRNEREK---ERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYI 198
+ Q++ E+EK E++ L E++ RE+EE ++ E++ +++ +
Sbjct: 314 EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373
Query: 199 QKTERKSGKRQTEREKKKKILAERRKVLAIDHL---NEDQLREKAKELWQSIYNL-EAEK 254
Q+ ER + + RE+++K+ + ++ D E+++RE+ K +W+ + + E +K
Sbjct: 374 QE-ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK-MWEQVEKMREEKK 431
Query: 255 FDLQEKFKQQKYEINVLRNRINDNQK 280
QEK + + E RI + +K
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREK 457
Score = 51.6 bits (122), Expect = 8e-07
Identities = 49/190 (25%), Positives = 85/190 (44%), Gaps = 15/190 (7%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDED---EQEEAAEEDAEAEAETEETRAEEDEE--E 59
E+ + E+ +EE+ E E+ RE+E+ EQEE +E E E EE E++E+ E
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE 759
Query: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKR-MEKDLNELQALIEA 118
+E K E + E K K KI + E D + R E+ + + +
Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRG 819
Query: 119 HFENRKKEEEELVSLKDRI---------ERRRAERAEQQRIRNEREKERQNRLAEERARR 169
E +EE++ ++++ + + E Q + RE+E + R EE+ R
Sbjct: 820 QEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMRE 879
Query: 170 EEEENRRKAE 179
+EE+ R + E
Sbjct: 880 QEEKMRGQEE 889
Score = 28.5 bits (62), Expect = 7.4
Identities = 13/60 (21%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDE---DEQEEAAEEDAEAEAETEETRAEEDE 57
M + + + E+ E+ + E E+E+ W ++E D++E+ ++ + + E+ R +E++
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEK 823
Score = 28.5 bits (62), Expect = 7.4
Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 11/89 (12%)
Query: 1 MSDIEEVVEEYEE-EEQEEAAVEEEEDWREDEDE----------QEEAAEEDAEAEAETE 49
M + E++ E+ E+ +QEE +EE R E++ QEE E E
Sbjct: 783 MQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQE 842
Query: 50 ETRAEEDEEEEEAKEAEDGPMEESKPKPR 78
E ++E+ EE + ++ M E + K R
Sbjct: 843 EKMWGQEEKMEEKMQGQEEKMREQEEKMR 871
Score = 28.5 bits (62), Expect = 7.4
Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 5 EEVVEEYEEE---EQEEAAVEEEEDWREDEDE--QEEAAEEDAEAEAETEETRAEEDEEE 59
EE + EE+ ++E+ +EE+ W ++E QEE EE + + E + E+ +
Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ 873
Query: 60 EEAKEAEDGPMEESKPK 76
EE ++ M + K
Sbjct: 874 EEKMREQEEKMRGQEEK 890
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 72.4 bits (176), Expect = 4e-13
Identities = 60/290 (20%), Positives = 140/290 (48%), Gaps = 18/290 (6%)
Query: 6 EVVEEYEEEEQEEAAVEEEE-DWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
+V E+ + ++E V E+E RE E + E + E E + E + E+EE+ ++
Sbjct: 158 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQK 217
Query: 65 AED--GPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFEN 122
E+ G EE K M E+V + ++ E+ + E + E
Sbjct: 218 QEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQE-------EQ 270
Query: 123 RKKEEEELVSLKDRIER--RRAERAEQQRIRNEREKERQNRLAE-ERARREEEENRRKAE 179
+++EE+++ K++ E+ + E+ EQ R + E+ +E++ ++ E E RE+EE K E
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330
Query: 180 DEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREK 239
++ ++K M + K E + G+++ + +K+++ + ++ + + E+Q+R++
Sbjct: 331 EQMWEQK--EQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQM---RKQEEQMRKQ 385
Query: 240 AKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAK 289
+++ + + +K + E+ +Q + + + + +K + G+ K
Sbjct: 386 EEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
Score = 72.0 bits (175), Expect = 6e-13
Identities = 52/245 (21%), Positives = 124/245 (50%), Gaps = 30/245 (12%)
Query: 1 MSDIEEVVEEYEEE--EQEEAAVEEEEDWREDE----DEQEEAAEEDAEAEAETEETRAE 54
M + EE + E EE+ +QEE E+EE R+ E +++E+ +++ + + + E+ R +
Sbjct: 201 MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQ 260
Query: 55 ED---EEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNE 111
E+ E+EE+ +E E+ +++ + + E++ + + E+ + E
Sbjct: 261 EEQMREQEEQMREQEEQMLKQKEQTEQEEQTG------EQEEQMREQEEQMREQEEQMRE 314
Query: 112 LQALIEAHFENRKKEEEELVSLKDRI----------ERRRAERAEQQRIRNE--REKERQ 159
+ + E K+EE++ K+++ E + E+ EQ + + E R++E Q
Sbjct: 315 QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQ 374
Query: 160 NRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKIL 219
R EE+ R++EE+ R++ E +K+ + +++ E + G+++ + K+++ +
Sbjct: 375 MRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKE---QMREQEEQMGEQKEQMRKQEEHM 431
Query: 220 AERRK 224
E+++
Sbjct: 432 GEQKE 436
Score = 52.4 bits (124), Expect = 5e-07
Identities = 52/281 (18%), Positives = 127/281 (45%), Gaps = 22/281 (7%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDG 68
+E + EQE E+E RE E + E + E E + E + E+E + +E ++G
Sbjct: 50 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE-QEG 108
Query: 69 PMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEE 128
+ E + + R +G+ V + + E + E + + +++E
Sbjct: 109 QVREQEGQVRE----------QEGQ-VREQEGQVREQEGQVREQEGQVREQEGQVREQEG 157
Query: 129 ELVSLKDRIERRRAERAEQQRIRNERE---KERQNRLAEERARREEEENRRKAEDEARKK 185
++ + ++ + + EQ+ E+E +E++ ++ E+ + E+E + E E + +
Sbjct: 158 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQE-EQMGEQEEQMQ 216
Query: 186 KALSNMMHFGGYIQKTERKSGKR----QTEREKKKKILAERRKVLAIDHLNEDQLREKAK 241
K M ++K E + G++ Q + E+ +K + RK E+Q+RE+ +
Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEE 276
Query: 242 ELWQSIYNLEAEK--FDLQEKFKQQKYEINVLRNRINDNQK 280
++ + E E+ + +E+ ++Q+ ++ ++ + ++
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE 317
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 72.0 bits (175), Expect = 6e-13
Identities = 69/295 (23%), Positives = 131/295 (44%), Gaps = 31/295 (10%)
Query: 1 MSDIEEVVEEYEEE--EQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEE 58
M + E + E EE+ QEE E+EE RE ED+ E+ E E + E + +
Sbjct: 313 MCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372
Query: 59 EEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEA 118
EE+ +E ++ E+ + R KI + E + + R+ EK + E I
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQ------EEKIREQEEKRQEKMWRQ--EKKMREQDEKIRE 424
Query: 119 HFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKA 178
E ++EE++ L++ ++ + + E + E E++ Q + EE+ +R+EE+ + +
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ--EEKIQRQEEKIQEQE 482
Query: 179 EDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE 238
E R++K L +K R+ K + EK ++ + ++ E+++RE
Sbjct: 483 EKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR-------QEEKMRE 535
Query: 239 KAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRIND-NQKVSKTRGKAKVTG 292
+ LWQ +EK ++Q+ + L R+ QK G + +G
Sbjct: 536 QEVRLWQQ-----------EEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Score = 45.4 bits (106), Expect = 6e-05
Identities = 54/296 (18%), Positives = 133/296 (44%), Gaps = 32/296 (10%)
Query: 12 EEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA----KEAED 67
EE +++ A ++E+ E E + + +D + + E + + + + EA KE +
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 68 GPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEE 127
+ + + NL+ + E++ + + E+ + E + I E ++E
Sbjct: 274 VSAKLQAQVEENELWNLLNQQ--QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 128 EELVSLKDRIERRRAER-AEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKK 186
E++ +++I + + ++++IR + EK R+ EE+ R+EE+ R + E +++
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ---EEKMWRQEEKIREQDEKIQEQEE 388
Query: 187 ALSNMMHFGGYIQKTERKSGKRQTE---------------REKKKKILAERRKVLAIDHL 231
+ +K + KRQ + RE+++++ + K+ ++ +
Sbjct: 389 EMWRQE------EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEM 442
Query: 232 NEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 287
+DQ EK +E+ + + E + + +EK ++Q+ +I + +K+ K K
Sbjct: 443 MQDQ-EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Score = 30.8 bits (68), Expect = 1.5
Identities = 38/174 (21%), Positives = 74/174 (42%), Gaps = 37/174 (21%)
Query: 103 KRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNERE--KERQN 160
KR+ L + +A+ +A + KK +E+ K ++R+ + E+ +R K+
Sbjct: 104 KRVTFTLPDDEAIEDAGVSHVKKNSDEV---KSSFKKRQEKMNEKNYTFRKRVVIKKPWL 160
Query: 161 RLAEERARREEEENRRKAEDEARKKKALSNMMHF------GGYIQKTERKSGKRQTEREK 214
RL E A++ E + L +HF G YI+K ++ E
Sbjct: 161 RLGEVTAQKRPENS------------LLEETLHFDHAVRMGTYIEKLTKERDAPSLE--- 205
Query: 215 KKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEI 268
L + + +++L+EK EL + + +E+EK ++Q K K ++
Sbjct: 206 -----------LYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 72.0 bits (175), Expect = 6e-13
Identities = 69/295 (23%), Positives = 131/295 (44%), Gaps = 31/295 (10%)
Query: 1 MSDIEEVVEEYEEE--EQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEE 58
M + E + E EE+ QEE E+EE RE ED+ E+ E E + E + +
Sbjct: 313 MCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372
Query: 59 EEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEA 118
EE+ +E ++ E+ + R KI + E + + R+ EK + E I
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQ------EEKIREQEEKRQEKMWRQ--EKKMREQDEKIRE 424
Query: 119 HFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKA 178
E ++EE++ L++ ++ + + E + E E++ Q + EE+ +R+EE+ + +
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ--EEKIQRQEEKIQEQE 482
Query: 179 EDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE 238
E R++K L +K R+ K + EK ++ + ++ E+++RE
Sbjct: 483 EKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR-------QEEKMRE 535
Query: 239 KAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRIND-NQKVSKTRGKAKVTG 292
+ LWQ +EK ++Q+ + L R+ QK G + +G
Sbjct: 536 QEVRLWQQ-----------EEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Score = 45.4 bits (106), Expect = 6e-05
Identities = 54/296 (18%), Positives = 133/296 (44%), Gaps = 32/296 (10%)
Query: 12 EEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEA----KEAED 67
EE +++ A ++E+ E E + + +D + + E + + + + EA KE +
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 68 GPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEE 127
+ + + NL+ + E++ + + E+ + E + I E ++E
Sbjct: 274 VSAKLQAQVEENELWNLLNQQ--QEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 128 EELVSLKDRIERRRAER-AEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKK 186
E++ +++I + + ++++IR + EK R+ EE+ R+EE+ R + E +++
Sbjct: 332 EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ---EEKMWRQEEKIREQDEKIQEQEE 388
Query: 187 ALSNMMHFGGYIQKTERKSGKRQTE---------------REKKKKILAERRKVLAIDHL 231
+ +K + KRQ + RE+++++ + K+ ++ +
Sbjct: 389 EMWRQE------EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEM 442
Query: 232 NEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 287
+DQ EK +E+ + + E + + +EK ++Q+ +I + +K+ K K
Sbjct: 443 MQDQ-EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Score = 30.8 bits (68), Expect = 1.5
Identities = 38/174 (21%), Positives = 74/174 (42%), Gaps = 37/174 (21%)
Query: 103 KRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNERE--KERQN 160
KR+ L + +A+ +A + KK +E+ K ++R+ + E+ +R K+
Sbjct: 104 KRVTFTLPDDEAIEDAGVSHVKKNSDEV---KSSFKKRQEKMNEKNYTFRKRVVIKKPWL 160
Query: 161 RLAEERARREEEENRRKAEDEARKKKALSNMMHF------GGYIQKTERKSGKRQTEREK 214
RL E A++ E + L +HF G YI+K ++ E
Sbjct: 161 RLGEVTAQKRPENS------------LLEETLHFDHAVRMGTYIEKLTKERDALSLE--- 205
Query: 215 KKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEI 268
L + + +++L+EK EL + + +E+EK ++Q K K ++
Sbjct: 206 -----------LYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKL 248
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 71.2 bits (173), Expect = 1e-12
Identities = 64/284 (22%), Positives = 130/284 (45%), Gaps = 24/284 (8%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDG 68
EE EEE+ + ++ E + E++ E+ EE + + +EE ++EEE ++ D
Sbjct: 191 EEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDE 250
Query: 69 PMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRM----EKDLNELQALIEAHFENRK 124
K + + + ER + R+R+ +K + + +A IEA +
Sbjct: 251 ISHHEKMEEED-------KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAA 303
Query: 125 KEEEELVSLKDRIERRRAERAEQQRIRNERE--KERQNRLAEERARREEEENRRKAEDEA 182
+E E + E R R E++R ER+ KE + R AEER R +EEE +R AE+
Sbjct: 304 QERE-----RREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEE-KRAAEERQ 357
Query: 183 RKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKE 242
R K+ + E + K + E +K+ K L E++ + + +++ +K +
Sbjct: 358 RIKEEEKRAAEERQRARAEEEE--KAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEG 415
Query: 243 LWQSIYNLEAEKFD---LQEKFKQQKYEINVLRNRINDNQKVSK 283
W + + +K L+++ +++ ++ R ++ +++ K
Sbjct: 416 KWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFK 459
Score = 65.9 bits (159), Expect = 4e-11
Identities = 83/331 (25%), Positives = 134/331 (40%), Gaps = 59/331 (17%)
Query: 2 SDIEEVVEEYEEEEQEEAAV---------------EEEEDWREDEDEQEEAAEEDAEAEA 46
+ +E +VEE E QEE V EEE + DE E EE+ + A
Sbjct: 206 NQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERA 265
Query: 47 ETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRME 106
E E R E EE E K +D + + + + + K ER + R+RM
Sbjct: 266 EAERARLEA-EERERIKAEQDKKIADERARIEA------EEKAAAQERERREAEERERMR 318
Query: 107 KDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREK---ERQNRLA 163
++ + E K+ EE +K+ E+R AE E+QRI+ E ++ ERQ A
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEE-EKRAAE--ERQRIKEEEKRAAEERQRARA 375
Query: 164 EERARREEEENRRKAEDEARK------------------------KKALSNMMHFGGYIQ 199
EE + + EE +R + E +K KKA + + +
Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435
Query: 200 KTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQE 259
+ E K K Q +REK L E + + + +++++ K KE + + + K E
Sbjct: 436 QGEEKGTKVQAKREK----LQEDKPTFKKEEIKDEKIK-KDKEPKEEVKSFMDRKKGFTE 490
Query: 260 KFKQQKYEINVLRNRINDNQKVSKTRGKAKV 290
K Q E + + +N S+ G+A V
Sbjct: 491 -VKSQNGEFMTHKLKHTEN-TFSRPGGRASV 519
Score = 61.2 bits (147), Expect = 1e-09
Identities = 77/299 (25%), Positives = 128/299 (42%), Gaps = 46/299 (15%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
+S E EE E+ +E + E E++ E+ EA EAE E E +AE+D+
Sbjct: 233 ISSEEPKQEEEREQGSDE--ISHHEKMEEEDKERAEAERARLEAE-ERERIKAEQDK--- 286
Query: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
K A++ E++ K + + ER + ++ R R E+ A
Sbjct: 287 --KIADERARIEAEEKAAA----------QERERREAEERERMREEEKR-------AAEE 327
Query: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNERE--KERQNRLAEERARREEEENRRKA 178
R KEEE K E R+ + E++R ER+ KE + R AEER R EE +
Sbjct: 328 RQRIKEEE-----KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAK 382
Query: 179 EDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKK----KKILAERRKVLAIDHLNED 234
+E ++ K L H +Q+T+ K K + + E K KK ++ + + E+
Sbjct: 383 VEEQKRNKQLEEKKH---AMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEE 439
Query: 235 Q------LREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 287
+ REK +E + + E K + +K K+ K E+ +R +V G+
Sbjct: 440 KGTKVQAKREKLQE-DKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 497
Score = 53.9 bits (128), Expect = 2e-07
Identities = 43/187 (22%), Positives = 97/187 (51%), Gaps = 17/187 (9%)
Query: 8 VEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEE--TRAEEDEEEEEAKEA 65
V+ E+ QE+ ++E+ ++++ ++++ +E+ ++ + ++ T + E +
Sbjct: 444 VQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKL 503
Query: 66 EDGPMEESKPKPRSFMPNLVP---PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFEN 122
+ S+P R+ + P++ G+R++ ++ R+R E + E + L
Sbjct: 504 KHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLE--ELRRRRGETESEEFEKL------- 554
Query: 123 RKKEEE---ELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
++K++E EL LK + E RR E+++ R + E +R+ R EE+ R +EE RR+AE
Sbjct: 555 KQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAE 614
Query: 180 DEARKKK 186
+++K
Sbjct: 615 AAEKRQK 621
Score = 53.5 bits (127), Expect = 2e-07
Identities = 70/308 (22%), Positives = 129/308 (41%), Gaps = 47/308 (15%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDE-------------DEQEEAAEEDAEAEAETEETRAEE 55
E +E+E+ A EE + R E +E++ AAEE A AE EE E
Sbjct: 327 ERQRIKEEEKRAAEERQ--RIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE 384
Query: 56 DEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIH----RKRMEKDLNE 111
+++ + E + M+E+K K + + K + ++ D + +K+ E+ +
Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEK-VEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK 443
Query: 112 LQALIEAHFENR---KKEE-------------EELVSLKDRIERRRAERAEQQRIRNERE 155
+QA E E++ KKEE EE+ S DR + +++ +
Sbjct: 444 VQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKL 503
Query: 156 KERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGG-----YIQKTERKSGKRQT 210
K +N + R + + + K L + G +K ++K +
Sbjct: 504 KHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL 563
Query: 211 EREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINV 270
E E+ KK ERRKV L E++ R K +E + + E EK L+E+ ++++ E
Sbjct: 564 ELEELKKKREERRKV-----LEEEEQRRKQEEADRKLRE-EEEKRRLKEEIERRRAEAAE 617
Query: 271 LRNRINDN 278
R ++ ++
Sbjct: 618 KRQKMPED 625
Score = 48.5 bits (114), Expect = 7e-06
Identities = 56/277 (20%), Positives = 114/277 (41%), Gaps = 58/277 (20%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETE----------------ETR 52
E+ EE++ A EEEE + +E ++ + EE A ET+ E +
Sbjct: 363 EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK 422
Query: 53 AEEDEEE----EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKD 108
A+ED+ + ++ E + ++ + K + P +I D E++ D ++ ++
Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKD-EKIKKDKEPKEEVKSF 481
Query: 109 LNELQALIEA-------------HFEN-------------RKKEEEELVSLKDRIERRRA 142
++ + E H EN ++ E V R+E R
Sbjct: 482 MDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRR 541
Query: 143 ERAEQQRIRNEREKERQNRLAEE----RARREEEENRRKAEDEARKKKALSNMMHFGGYI 198
R E + E+ K++Q A E + +REE + E++ RK++ +
Sbjct: 542 RRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL------ 595
Query: 199 QKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQ 235
+ E + + + E E+++ AE+R+ + D L++D+
Sbjct: 596 -REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDK 631
Score = 45.8 bits (107), Expect = 4e-05
Identities = 65/332 (19%), Positives = 127/332 (38%), Gaps = 62/332 (18%)
Query: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEE-------------------- 40
M D E E ++ +E E ++ ++D++EEAA E
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 41 ---------------DAEAEAETEETRAEEDEEE------EEAKEAEDGPMEESKPKPRS 79
D EA+ T T+ E D+E +E ++E+ + +
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120
Query: 80 FMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVS----LKD 135
F P + + R + E + E + E+ E + EE E V+ D
Sbjct: 121 FDPTITDASLSLPSR----RMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND 176
Query: 136 RIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG 195
+ ++ ++++ E EK ++ + E + EE ++++E + +
Sbjct: 177 WRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSE 236
Query: 196 GYIQKTERKSGK------RQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYN 249
Q+ ER+ G + E E K++ AER ++ A + E E+ K++
Sbjct: 237 EPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEE--RERIKAEQDKKIADERAR 294
Query: 250 LEA-EKFDLQEKFKQQKYEINVLRNRINDNQK 280
+EA EK QE+ +++ E R R+ + +K
Sbjct: 295 IEAEEKAAAQERERREAEE----RERMREEEK 322
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 3/121 (2%)
Query: 6 EVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEA 65
E+ E ++ E+ +EEEE R+ E+ + EE+ + + E R + E+ K
Sbjct: 564 ELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMP 623
Query: 66 EDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKK 125
EDG ++ KP + F P KI ER +F + ++ + QA I + ++R +
Sbjct: 624 EDGLSDDKKPF-KCFTPKGSSLKIE--ERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLE 680
Query: 126 E 126
+
Sbjct: 681 Q 681
>gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]
Length = 439
Score = 71.2 bits (173), Expect = 1e-12
Identities = 70/294 (23%), Positives = 138/294 (46%), Gaps = 29/294 (9%)
Query: 8 VEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAK---- 63
+E +EE++E +++ ++ + +EQEE + D + R ED EE A+
Sbjct: 50 MESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRL--QNRISEDVEERLARHRKI 107
Query: 64 -EAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFEN 122
E E +S+ + ++ + E +D ++I R+R ++ +
Sbjct: 108 VEPEVVGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRR---------GMMRQRAQE 158
Query: 123 RKKEEEELVSLKDRIERRRAERAEQQRIRNE---REKERQNRLAEERARREEEENRRKAE 179
RK EE E++ ++D E R E +E + E E E + RL R+++ ++ E
Sbjct: 159 RKNEEMEVMEVED--EGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQERE 216
Query: 180 DEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLN-EDQLRE 238
EA K+K L + + RK + E E KK++ +R + A+D LN +D+ E
Sbjct: 217 AEALKQKELEQEAK---RMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDE 273
Query: 239 KAKELW--QSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKV 290
+ E W + + ++ ++ D +E +++K EI +RN + + ++ ++ R KV
Sbjct: 274 EEYEAWKVRELKRIKRDRED-REALEKEKAEIERMRN-LTEEERRAELRANGKV 325
Score = 50.8 bits (120), Expect = 1e-06
Identities = 65/251 (25%), Positives = 102/251 (40%), Gaps = 51/251 (20%)
Query: 6 EVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE-EAKE 64
EVV E + E + +A E ED E+E+EE +E+ E RA+E + EE E E
Sbjct: 111 EVVGESDSEVEGDAWRMERED--SSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVME 168
Query: 65 AED----GPMEESKPKPRSFM-------PNLVPPKIPDGERV-----DFDDIHRKRMEKD 108
ED G ES+ + + P L P I +RV + + + +K +E++
Sbjct: 169 VEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQE 228
Query: 109 LNELQ--------------------------ALIEAHFENRKKEEEELVSLKDRIERRRA 142
+ A ++A + + +EEE + K R E +R
Sbjct: 229 AKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVR-ELKRI 287
Query: 143 ERAEQQRIRNEREK---ERQNRLAEERARREEEENRRKAEDEA--RKKKALSNMMHFGGY 197
+R + R E+EK ER L EE R E N + ++A K K L H G +
Sbjct: 288 KRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAF 347
Query: 198 IQKTERKSGKR 208
+ + KR
Sbjct: 348 FMDEDEEVYKR 358
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 68.9 bits (167), Expect = 5e-12
Identities = 56/300 (18%), Positives = 135/300 (45%), Gaps = 21/300 (7%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDED-EQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAED 67
EE E++++ +EE+ WR++E ++E + E + +E R E +E+E +E E
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLRE--QEKELREQEK 297
Query: 68 GPMEESKPKPRSFMPNLVPPKI-PDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKE 126
E+ K + + K+ E++ + R E+ L E + + + + +
Sbjct: 298 ELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 357
Query: 127 EEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKK 186
EE + +R+ + EQ+++ + EK ++ ER ++ EE E E + +K
Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQK 417
Query: 187 ALSNMMH------FGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHL--------N 232
NM + + + K +++ +E+++KI + K+ + +
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 233 EDQLREKAKELW---QSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAK 289
++++RE+ ++W + + + E + +D +E+ +Q + R+ + +K+ + K +
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Score = 68.9 bits (167), Expect = 5e-12
Identities = 64/284 (22%), Positives = 141/284 (49%), Gaps = 30/284 (10%)
Query: 1 MSDIEEVVEEYEEE--EQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEE 58
M D EE + E +E E+EE E+E+ W ++E QEE + E + EE E EE
Sbjct: 354 MRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE 413
Query: 59 EEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALI-- 116
+ + +E EE + + + ++P+ + ++ + E+ + E + I
Sbjct: 414 KMQKQEENMWEQEEKEWQQQ---------RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 464
Query: 117 -EAHFENRKK--EEEELVSLKDRI-ERRRAERAEQQRIRNEREK--ERQNRLAEERARRE 170
E + KK +E++ +D++ E+ R ++Q++ ++ E+ E+ RL E+ R
Sbjct: 465 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR 524
Query: 171 EEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKK----KKILAERRKVL 226
E++ + E++ R++K + + Q+ + + +R EREKK ++++ E+ + +
Sbjct: 525 EQKKMWQQEEKMREEKK-TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 583
Query: 227 AIDHLNEDQLREKAKELW---QSIYNLEAEKFDLQEKFKQQKYE 267
E+++RE+ +++W + + E + ++ +EK +Q+ E
Sbjct: 584 ---QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Score = 66.2 bits (160), Expect = 3e-11
Identities = 68/279 (24%), Positives = 132/279 (47%), Gaps = 39/279 (13%)
Query: 1 MSDIEEVVEEYEEE--EQEEAAVEEEEDWR-----EDED---EQEEAAEEDAEAEAETEE 50
M + EE + E EE+ +QEE +E++ WR E ED EQEE + + + EE
Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 507
Query: 51 TRAEEDEE--EEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKD 108
E+DE E+E + E M + + K R K + E+ +D + R E+
Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMRE------EKKTQEQEKKTWDQEEKMREEER 561
Query: 109 LNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERAR 168
+ E E + +EEEE++ + E + E+ E+ R + E+ E++ ++ E+ +
Sbjct: 562 MRER--------EKKMREEEEMMREQ---EEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Query: 169 R-EEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTE-REKKKKILAERRKVL 226
E+EE + E+E + ++ M +Q+ E K +++ + RE+++K+ + K+
Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
Query: 227 AIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQK 265
+ EK +E + + E + + +EK + Q+
Sbjct: 671 GQE--------EKMREQEEKMQGQEEKMREQEEKMRGQE 701
Score = 65.9 bits (159), Expect = 4e-11
Identities = 66/290 (22%), Positives = 133/290 (45%), Gaps = 25/290 (8%)
Query: 1 MSDIEEVVEEYEEE--EQEEAAVEEEEDWREDED---EQEEAAEEDAEAEAETEETRAEE 55
M + EE + E EE+ QEE E+E+ RE E +QEE E E E EE E+
Sbjct: 319 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378
Query: 56 D---EEEEEAKE------------AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDI 100
+ E+EE+ +E E+ M E + K + N+ + + ++ +
Sbjct: 379 EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 438
Query: 101 HRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKER-- 158
K E++ + Q E + +++EE+ + ++ R+ R ++ ++ + EK R
Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 498
Query: 159 -QNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKR--QTEREKK 215
Q +E E++E R+ E+ R++K + +KT+ + K Q E+ ++
Sbjct: 499 EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMRE 558
Query: 216 KKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQK 265
++ + ER K + + + EK +E + + E + ++ +EK ++Q+
Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608
Score = 62.8 bits (151), Expect = 4e-10
Identities = 55/268 (20%), Positives = 128/268 (47%), Gaps = 41/268 (15%)
Query: 23 EEEDWREDED--EQEEAAEEDAEAEAETEETRAEED----EEEEEAKEAEDGPMEESKPK 76
+EE WR++E+ EQE+ + E EE E++ E+EE+ + E E+ K
Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK-- 290
Query: 77 PRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDR 136
++ + E+ + + E+ + E + + E +++EE++ ++R
Sbjct: 291 -----------ELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
Query: 137 I-ERRRAERAEQQRIRNEREK--ERQNRLAEERARREEEENRRKAEDEARKKKALSNMMH 193
+ E+ + R ++Q++R++ E+ E+ RL E+ R E+E + E++ ++++ +
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR---- 395
Query: 194 FGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAE 253
++ ++ + +T RE+++K+ + E+ ++ KE Q + E
Sbjct: 396 -----EREKKMREEEETMREQEEKMQKQE----------ENMWEQEEKEWQQQRLPEQKE 440
Query: 254 KFDLQEKFKQQKYEINVLRNRINDNQKV 281
K QEK ++Q+ +I +I D +++
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Score = 61.2 bits (147), Expect = 1e-09
Identities = 53/214 (24%), Positives = 99/214 (46%), Gaps = 23/214 (10%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDED---EQEEAAEEDAEAEAETEETRAEEDEEEEE 61
E++ EE E+E+ EEEE RE E+ EQEE E E E EE E++E+ E
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613
Query: 62 AKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKR-MEKDLNELQALIEAHF 120
+E EE K + + M K+ + E ++ + R E+ + E + ++
Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Query: 121 ENRKKEEEELVSLKDRI-ERRRAERAEQQRIRNEREK---------------ERQNRLAE 164
E +++EE++ ++++ E+ R +++++ + EK E++ R+ +
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRD 733
Query: 165 ERARREE---EENRRKAEDEARKKKALSNMMHFG 195
++ + +E E R +E K L NM H G
Sbjct: 734 QKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTG 767
Score = 58.9 bits (141), Expect = 5e-09
Identities = 57/284 (20%), Positives = 130/284 (45%), Gaps = 43/284 (15%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
+E+ E+ + EQEE E+EE E E++ E E+ E E + E+E++ ++
Sbjct: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
Query: 65 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK 124
E+ E+ + ++ + E + E+ + E + + E E +
Sbjct: 357 QEERMWEQDE-------------RLREKEERMREQEKMWEQEEKMQEEERIRER--EKKM 401
Query: 125 KEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEA-R 183
+EEEE + R + + ++ E+ E ++ +Q RL E++ + E+E ++ E++
Sbjct: 402 REEEETM----REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 457
Query: 184 KKKALSNMMHFGGYIQKTERKSGKRQTE----------REKKKKILAERRKVLAIDHL-- 231
+++ + + G +K R+ R+ E R++++K+ + ++ D
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
Query: 232 -NEDQLREKAKELWQSIYNLEAEK---------FDLQEKFKQQK 265
E+++RE+ K++WQ + EK +D +EK ++++
Sbjct: 518 EKEERMREQ-KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Score = 58.5 bits (140), Expect = 7e-09
Identities = 55/241 (22%), Positives = 116/241 (48%), Gaps = 20/241 (8%)
Query: 1 MSDIEEVVEEYEEE--EQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDE- 57
M D EE + E +E E+EE E+++ W+++E +EE ++ E + +E + E+E
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561
Query: 58 ---------EEEEAKEAEDGPMEESKPKPRSFMPNL--VPPKIPDGERVDFDDIHRKRME 106
EEEE ++ M+E + K R + K+ + E ++ + +
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621
Query: 107 KDLNELQALIEAHFENRKK--EEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAE 164
++ +++Q E +E +K E+EE + ++ R + E+ +Q + + ++E+ R E
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM-REQE 680
Query: 165 ERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRK 224
E+ + +EE+ R E E + + M + E K ++ REK+++I ++ K
Sbjct: 681 EKMQGQEEKMR---EQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK 737
Query: 225 V 225
+
Sbjct: 738 M 738
Score = 44.3 bits (103), Expect = 1e-04
Identities = 49/296 (16%), Positives = 129/296 (43%), Gaps = 46/296 (15%)
Query: 25 EDWREDEDEQEEAAEEDAEAEAET------EETRAEED--EEEEEAKEAEDGPMEESKP- 75
ED ++ + +EA + EA+ T ++T E ++ A++ EDG + ESK
Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDL 129
Query: 76 --------------------------KPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDL 109
K ++ L + + + I + ++K
Sbjct: 130 AGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKN 189
Query: 110 NELQALIEAHFENRKKEEEELVSLKDRIERRR--AERAEQQRIRNEREKERQNRLAEERA 167
ELQ + + + + + LK ++ER + + + ++ E ++ + +E+
Sbjct: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
Query: 168 RREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLA 227
R++EE + E+ R+++ M +++ E++ +++ E +++K L E++K+
Sbjct: 250 IRKQEEKMWRQEERLREQEG--KMREQEEKMRRQEKRLREQEKELREQEKELREQKKL-- 305
Query: 228 IDHLNEDQLREKAKELW---QSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 280
E+Q++E+ +++W + + E + + +E+ +Q+ ++ ++ D ++
Sbjct: 306 --REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 68.6 bits (166), Expect = 6e-12
Identities = 59/225 (26%), Positives = 101/225 (44%), Gaps = 30/225 (13%)
Query: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE 64
EE E E E+ E EEE +W +E+E E EE+ E E E E EE+E E E +E
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992
Query: 65 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK 124
E E + +GE ++ + E++ E++ +E +
Sbjct: 993 EEGEEEGEEE---------------GEGE----EEGEGEGEEEEEGEVEGEVEGEEGEGE 1033
Query: 125 KEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARK 184
EEEE ++ ER + E+ R E E+E + + E EEEN R+ +E +K
Sbjct: 1034 GEEEE--GEEEGEEREKEGEGEENRRNREEEEEEEGKYQE----TGEEENERQDGEEYKK 1087
Query: 185 KKALSNMMHFGGYIQKTERKSGKRQTE---REKKKKILAERRKVL 226
+ + +G + KT +K T+ +E++ K+ + +++L
Sbjct: 1088 VSKIKGSVKYGKH--KTYQKKSVTNTQGNGKEQRSKMPVQSKRLL 1130
Score = 61.2 bits (147), Expect = 1e-09
Identities = 74/300 (24%), Positives = 121/300 (40%), Gaps = 14/300 (4%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDE----------QEEAAEEDAEAEAETEETR 52
++EE E EEEE+E EEE + E+E E +EE E + E E E E
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877
Query: 53 AEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNEL 112
EE+E E E +E +G EE + + + +GE ++ E + E
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937
Query: 113 QALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEE 172
+ E ++EE E ++ E E E + E E E + E EE
Sbjct: 938 EGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE 997
Query: 173 ENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLN 232
E + E E + + G + E + G+ + E E+ ++ ER K +
Sbjct: 998 EGEEEGEGE-EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENR 1056
Query: 233 EDQLREKAKE-LWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK--VSKTRGKAK 289
++ E+ +E +Q E E+ D +E K K + +V + QK V+ T+G K
Sbjct: 1057 RNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGK 1116
Score = 57.0 bits (136), Expect = 2e-08
Identities = 54/209 (25%), Positives = 82/209 (39%), Gaps = 42/209 (20%)
Query: 14 EEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEE----DEEEEEAKEAEDGP 69
EE A +++ RE ++ + E + E E E EE D EE+E KE E G
Sbjct: 660 EEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGH 719
Query: 70 MEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEE 129
+E + ME+ E E +R++EEE+
Sbjct: 720 QKE----------------------------RNQEMEEGGEEEHGEGEEEEGDREEEEEK 751
Query: 130 LVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREE--EENRRKAEDEARKKKA 187
E E E + + EREKE R EERA +EE EE + E E + +
Sbjct: 752 --------EGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803
Query: 188 LSNMMHFGGYIQKTERKSGKRQTEREKKK 216
GG ++ E + GK + E E+++
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEE 832
Score = 57.0 bits (136), Expect = 2e-08
Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 3/176 (1%)
Query: 10 EYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGP 69
E E + E + E+E+W++ + E++E E + + E + E EEE E E+G
Sbjct: 685 EMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD 744
Query: 70 MEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEE 129
EE + K ++ +GER + ++ RK+ E+ E + E + +EEE
Sbjct: 745 REEEEEKEGEGKEEGEGEEV-EGER-EKEEGERKKEERAGKEEKGEEEGD-QGEGEEEET 801
Query: 130 LVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKK 185
+++ E E E + + ERE+E + EE EEE E+E K
Sbjct: 802 EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857
Score = 57.0 bits (136), Expect = 2e-08
Identities = 68/289 (23%), Positives = 114/289 (39%), Gaps = 14/289 (4%)
Query: 10 EYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGP 69
E E E EE E EE+ E E E+EE E+ E E E EE + +EE EE + E+G
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872
Query: 70 MEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENR----KK 125
E + + +GE + + + E + E + + E +
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932
Query: 126 EEEELVSLKDRIERRRAE-----RAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
EEEE + E E E++ E E+E + E EEEE + E+
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992
Query: 181 EARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKA 240
E +++ G ++ G+ + E E + ++ E + + E++ E+
Sbjct: 993 EEGEEEGEEE-----GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEERE 1047
Query: 241 KELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAK 289
KE E+ + +E Q+ E R + +KVSK +G K
Sbjct: 1048 KEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVK 1096
Score = 56.2 bits (134), Expect = 3e-08
Identities = 49/179 (27%), Positives = 80/179 (44%), Gaps = 17/179 (9%)
Query: 9 EEYEEEEQEEAAVEEEEDWREDEDEQE-EAAEEDAEAEAETEETRAEEDEEEE-EAKEAE 66
EE+++ + EE +E E + E QE E E+ E E EE EE+EE+E E KE
Sbjct: 700 EEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEG 759
Query: 67 DGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKE 126
+G E + + +GER + ++ ++ + E E R +E
Sbjct: 760 EGEEVEGEREKE------------EGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807
Query: 127 EEELVSLK-DRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARK 184
+EE ++ +E + ER E++ E+E + EE EEEE K E+E +
Sbjct: 808 KEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGE--EEEGEGEEEEGEGKGEEEGEE 864
Score = 55.5 bits (132), Expect = 6e-08
Identities = 50/182 (27%), Positives = 82/182 (45%), Gaps = 12/182 (6%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQE-EAAEEDAEAEAETEETRAEE--DEEE 59
++EE EE E +EE EEE+ +E E ++E E E + E E E E + EE +EE
Sbjct: 726 EMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785
Query: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
+ +E + G EE + + R + +G V+ ++ + E++ E + E
Sbjct: 786 KGEEEGDQGEGEEEETEGRG-------EEKEEGGEVEGGEVEEGKGEREEEEEEG--EGE 836
Query: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
E + EEEE ++ E + E E+ E E+ EE EEE + E
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896
Query: 180 DE 181
+E
Sbjct: 897 EE 898
Score = 50.1 bits (118), Expect = 2e-06
Identities = 55/192 (28%), Positives = 79/192 (41%), Gaps = 28/192 (14%)
Query: 6 EVVEEYEEEEQEEAAVEEEEDWREDED---EQEEAAEEDAEAEAETEETRAEEDEEE--- 59
E EE E E +EE EE E RE E+ ++EE A ++ + E E ++ EE+E E
Sbjct: 746 EEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG 805
Query: 60 ---EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALI 116
EE E E G +EE K GER + ++ E+ E +
Sbjct: 806 EEKEEGGEVEGGEVEEGK-----------------GEREEEEEEGEGEEEEGEGEEEEGE 848
Query: 117 EAHFENRKKEEEELVSLKDRIERRRAE-RAEQQRIRNEREKERQNRLAEERARRE-EEEN 174
E K EEE + E E E++ E E+E + EE E EEE
Sbjct: 849 GEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG 908
Query: 175 RRKAEDEARKKK 186
+ E+E + K
Sbjct: 909 EGEGEEEEGEGK 920
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 68.2 bits (165), Expect = 8e-12
Identities = 69/298 (23%), Positives = 140/298 (46%), Gaps = 30/298 (10%)
Query: 8 VEEYEEEEQEEAAVEEEE----DWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAK 63
+E+ ++ E+ +AA E+E + R +E+E +E+ + E E R +++EE + +
Sbjct: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQE-EILRRQQEEERKRRE 775
Query: 64 EAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENR 123
E E ++ + R +R + R+R E++ + + + E R
Sbjct: 776 EEELARRKQEEALRR--------------QREQEIALRRQREEEERQQQEEALR-RLEER 820
Query: 124 KKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEAR 183
++EEEE ++ + ++ E A+ R E+E Q RL E R R EEE R + E+E R
Sbjct: 821 RREEEERRKQEELLRKQEEEAAKWAR----EEEEAQRRLEENRLRMEEEAARLRHEEEER 876
Query: 184 KKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAI---DHLNEDQLREKA 240
K+K L Q+ +++ R+ +++++++ LA+ + + N + +A
Sbjct: 877 KRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 936
Query: 241 KELWQSIYNLEAEK-FDLQEKFKQQKYEI--NVLRNRINDNQKVSKTRGKAKVTGRWK 295
I LE E+ L+E+ ++Q+ E+ + + + QK+S +K +G K
Sbjct: 937 TLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/221 (19%), Positives = 94/221 (42%), Gaps = 25/221 (11%)
Query: 4 IEEVVEEYEEEEQEEAAVEEEED----WREDEDEQEEAAEEDAEAEAETEETRAEEDEEE 59
+EE E EE ++E + ++E+ W +E+E + EE+ E E R +EEE
Sbjct: 817 LEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEEN-RLRMEEEAARLRHEEEE 875
Query: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
+ KE E ++ K R +R + R+ ++ + A ++
Sbjct: 876 RKRKELE---VQRQKELMR--------------QRQQQQEALRRLQQQQQQQQLAQMKLP 918
Query: 120 FENRKKEEEELVSLKDRIERRRAE--RAEQQRIRNEREKE-RQNRLAEERARREEEENRR 176
+ ++ + + + AE + E++R R RE++ RQ R + ++++++ ++
Sbjct: 919 SSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 978
Query: 177 KAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKK 217
K K Q+ R+ K+Q ++++ ++
Sbjct: 979 KLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1019
Score = 32.3 bits (72), Expect = 0.51
Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 7/95 (7%)
Query: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQE---EAAEEDAEAEAETEETRAEEDEEE 59
D E + E EEA ++ + +E E EA+EE + + + D +
Sbjct: 323 DEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQS 382
Query: 60 EEAK--EAEDGPMEE--SKPKPRSFMPNLVPPKIP 90
+EA E +D P E K + + M N +P K+P
Sbjct: 383 QEASQFERKDEPKTEQTEKAEEETRMENSLPAKVP 417
Score = 30.0 bits (66), Expect = 2.5
Identities = 24/107 (22%), Positives = 45/107 (42%), Gaps = 3/107 (2%)
Query: 16 QEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 75
Q+E EE+E DE EE ++ + + EE + + ++E ++ + +E S+
Sbjct: 307 QKEPIPEEQEMDFRPVDEGEECSDSEG---SHNEEAKEPDKTNKKEGEKTDRVGVEASEE 363
Query: 76 KPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFEN 122
P++ + P D + + RK K +A E EN
Sbjct: 364 TPQTSSSSARPGTPSDHQSQEASQFERKDEPKTEQTEKAEEETRMEN 410
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.124 0.325
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,878,385
Number of Sequences: 37866
Number of extensions: 698329
Number of successful extensions: 53607
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1445
Number of HSP's successfully gapped in prelim test: 1188
Number of HSP's that attempted gapping in prelim test: 7693
Number of HSP's gapped (non-prelim): 17158
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.