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Search of human proteins with 4758346
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758346 Fc fragment of IgG, receptor, transporter, alpha
[Homo sapiens]
(365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 758 0.0
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 758 0.0
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 150 1e-36
gi|4504417 major histocompatibility complex, class I-related [Ho... 149 3e-36
gi|62912479 major histocompatibility complex, class I, E precurs... 144 9e-35
gi|17986001 major histocompatibility complex, class I, B precurs... 142 6e-34
gi|52630342 major histocompatibility complex, class I, C precurs... 141 1e-33
gi|149158702 major histocompatibility complex, class I, F isofor... 140 1e-33
gi|149158698 major histocompatibility complex, class I, F isofor... 140 1e-33
gi|24797067 major histocompatibility complex, class I, A precurs... 139 5e-33
gi|4504415 major histocompatibility complex, class I, G precurso... 130 2e-30
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 127 2e-29
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 122 4e-28
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 119 6e-27
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 116 4e-26
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 109 4e-24
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 99 8e-21
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 88 1e-17
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 84 2e-16
gi|110618224 CD1A antigen precursor [Homo sapiens] 81 1e-15
gi|4502649 CD1D antigen precursor [Homo sapiens] 76 4e-14
gi|4502645 CD1B antigen precursor [Homo sapiens] 76 5e-14
gi|110618240 CD1E antigen isoform a precursor [Homo sapiens] 74 3e-13
gi|110618230 CD1E antigen isoform b precursor [Homo sapiens] 74 3e-13
gi|149158700 major histocompatibility complex, class I, F isofor... 69 9e-12
gi|110618227 CD1C antigen precursor [Homo sapiens] 65 7e-11
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 64 2e-10
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 63 4e-10
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 62 8e-10
gi|110618232 CD1E antigen isoform c precursor [Homo sapiens] 61 1e-09
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 758 bits (1958), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
Sbjct: 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
Query: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE 120
YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
Sbjct: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE 120
Query: 121 LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF 180
LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
Sbjct: 121 LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF 180
Query: 181 SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL 240
SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
Sbjct: 181 SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL 240
Query: 241 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV 300
AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
Sbjct: 241 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV 300
Query: 301 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV 360
VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
Sbjct: 301 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV 360
Query: 361 IPATA 365
IPATA
Sbjct: 361 IPATA 365
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 758 bits (1958), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
Sbjct: 1 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
Query: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE 120
YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
Sbjct: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE 120
Query: 121 LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF 180
LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
Sbjct: 121 LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF 180
Query: 181 SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL 240
SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
Sbjct: 181 SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL 240
Query: 241 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV 300
AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
Sbjct: 241 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV 300
Query: 301 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV 360
VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
Sbjct: 301 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV 360
Query: 361 IPATA 365
IPATA
Sbjct: 361 IPATA 365
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 150 bits (380), Expect = 1e-36
Identities = 102/312 (32%), Positives = 159/312 (50%), Gaps = 18/312 (5%)
Query: 29 SLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRGEAEPCGAWVWENQVSWYWEK 86
SL Y TAVS P G P F G++ Q++ ++S EP W+ E + YW++
Sbjct: 41 SLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWM-EQEGPEYWDE 99
Query: 87 ETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCELGPDNTSVPT-AKFALNGEE 139
+T ++ + F L G G +TLQ + GC++GPD + + A +G +
Sbjct: 100 QTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGRD 159
Query: 140 F--MNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHLERGRGNL 197
+ +N DL+ T A I++R ++ AA ++ +L C LR +LE G+ L
Sbjct: 160 YIALNEDLRSWTAADT---AAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDAL 216
Query: 198 EWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQG--DFGPNSDG 255
+PP + P S L C A FYP E+ L + R G + P+ DG
Sbjct: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDG 276
Query: 256 SFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAV 315
+F ++L V SG+E Y C VQH GL +PL + E P ++S L++GI++G++LL A V
Sbjct: 277 TFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWE-PPQTSFLIMGIIVGLVLLVVALV 335
Query: 316 GGALLWRRMRSG 327
GA++WR+ RSG
Sbjct: 336 AGAVIWRKKRSG 347
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 149 bits (377), Expect = 3e-36
Identities = 101/344 (29%), Positives = 166/344 (48%), Gaps = 20/344 (5%)
Query: 11 LGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEP 70
L L++ L+ + +H SL Y VS P G P F G++ +Y+S+ + EP
Sbjct: 9 LPLIIVLMVKHSDSRTH-SLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67
Query: 71 CGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL----GGKGPYTLQGLLGCELGPDNT 126
W+ EN +WE+ T LR +++F K L G +T Q ++GCEL D +
Sbjct: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGS 127
Query: 127 SVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRL 186
+ ++A +G++F+ F+ +W A I Q W+ + +L C L
Sbjct: 128 TTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWL 187
Query: 187 REHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG--LAAGT 244
+ LE G+ L+ EPP +R+ + + PG + L C A FYPPE+ + +++NG +
Sbjct: 188 KRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEI 247
Query: 245 GQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIV 304
GD P+ DG++ A +S+ + + Y C V+H G+ L+V ES ++ LV+ V
Sbjct: 248 DYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQES--ETIPLVMKAV 305
Query: 305 IGVLLLTAAAVG-GALLWRRMRSGLPAPWISLRGDDTGVLLPTP 347
G ++L G G L+WRR R + + LPTP
Sbjct: 306 SGSIVLVIVLAGVGVLVWRRRP----------REQNGAIYLPTP 339
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 144 bits (364), Expect = 9e-35
Identities = 103/335 (30%), Positives = 167/335 (49%), Gaps = 22/335 (6%)
Query: 12 GLLLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG 66
G LL LL +L A SH SL Y T+VS P G P F G++ Q++ +++
Sbjct: 4 GTLLLLLSEALALTQTWAGSH-SLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAA 62
Query: 67 EAE--PCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLG 118
P W+ E + S YW++ET R ++F + L G G +TLQ + G
Sbjct: 63 SPRMVPRAPWM-EQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG 121
Query: 119 CELGPDNTSVPT-AKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177
CELGPD + +FA +G++++ + +W A IS++ A + +
Sbjct: 122 CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAV-DTAAQISEQKSNDASEAEHQRAY 180
Query: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
L +C L ++LE+G+ L EPP + P S + L C A FYP E+ L + +
Sbjct: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
Query: 238 NGLA--AGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295
+G T + P DG+F +++ V SG+E Y C VQH GL +P+ + + ++
Sbjct: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
Query: 296 SSVLVVGIVIGVLLL---TAAAVGGALLWRRMRSG 327
++ +VGI+ G++LL + AV A++WR+ SG
Sbjct: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSG 335
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 142 bits (357), Expect = 6e-34
Identities = 104/335 (31%), Positives = 166/335 (49%), Gaps = 26/335 (7%)
Query: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRG 66
+L LL +L A SH S+ Y T+VS P G P F G++ Q++ ++S
Sbjct: 9 VLLLLSAALALTETWAGSH-SMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASP 67
Query: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120
EP W+ E + YW++ T + + + E+ + L G G +TLQ + GC+
Sbjct: 68 REEPRAPWI-EQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYGCD 126
Query: 121 LGPDNTSVPTA-KFALNGEEF--MNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177
+GPD + ++A +G+++ +N DL+ T A I+QR + + A + +
Sbjct: 127 VGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADT---AAQITQRKWEAAREAEQRRAY 183
Query: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
L C LR +LE G+ LE +PP + P S + L C A FYP E+ L + R
Sbjct: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243
Query: 238 NG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295
+G T + P D +F +++ V SG+E Y C VQH GL +PL + E ++
Sbjct: 244 DGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQ 303
Query: 296 SSVLVVGIVIGVLLLTAAAVG---GALLWRRMRSG 327
S+V +VGIV G+ +L +G A++ RR SG
Sbjct: 304 STVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSG 338
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 141 bits (355), Expect = 1e-33
Identities = 109/336 (32%), Positives = 167/336 (49%), Gaps = 27/336 (8%)
Query: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRG 66
LL LL G L A SH S+ Y TAVS P G P F G++ Q++ ++S
Sbjct: 9 LLLLLSGGLALTETWACSH-SMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSDAASP 67
Query: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120
EP WV E + YW++ET + + + + + L G G +TLQ + GC+
Sbjct: 68 RGEPRAPWV-EQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMSGCD 126
Query: 121 LGPDNTSVPTA-KFALNGEEF--MNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177
LGPD + + A +G+++ +N DL+ T A I+QR + +AA + +
Sbjct: 127 LGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADT---AAQITQRKLEAARAAEQLRAY 183
Query: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
L +C LR +LE G+ L+ EPP + P S + L C A FYP E+ L + R
Sbjct: 184 LEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQR 243
Query: 238 NG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295
+G T + P DG+F +++ V SG E Y C +QH GL +PL + E ++
Sbjct: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQ 303
Query: 296 SSVLVVGIVIGVLLLTAAAVGG----ALLWRRMRSG 327
++ ++GIV G+ +L AV G A++ RR SG
Sbjct: 304 PTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSG 339
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 140 bits (354), Expect = 1e-33
Identities = 105/332 (31%), Positives = 163/332 (49%), Gaps = 22/332 (6%)
Query: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66
LL LL G+L A SH SL Y TAVS P G P + ++ Q+L ++S
Sbjct: 6 LLLLLSGALALTDTWAGSH-SLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
Query: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL------GGKGPYTLQGLLGCE 120
EP WV E + YWE T + + A + L G +TLQG+ GC+
Sbjct: 65 RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
Query: 121 LGPDNTSVPTA-KFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179
+GPD + + A +G+++++ + +W A I+QR+ + ++ A + T+L
Sbjct: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVA-QITQRFYEAEEYAEEFRTYLE 182
Query: 180 FSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG 239
C LR +LE G+ L+ +PP + P S + L C A FYP E+ L + R+G
Sbjct: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
Query: 240 --LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSS 297
T + P DG+F +++ V G+E Y C VQH GL QPL + E + +
Sbjct: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPT 302
Query: 298 VLVVGIVIGVLLLTAAAVG---GALLWRRMRS 326
+ +VGIV G+++L A G A++WR+ S
Sbjct: 303 IPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSS 334
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 140 bits (354), Expect = 1e-33
Identities = 105/332 (31%), Positives = 163/332 (49%), Gaps = 22/332 (6%)
Query: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66
LL LL G+L A SH SL Y TAVS P G P + ++ Q+L ++S
Sbjct: 6 LLLLLSGALALTDTWAGSH-SLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
Query: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL------GGKGPYTLQGLLGCE 120
EP WV E + YWE T + + A + L G +TLQG+ GC+
Sbjct: 65 RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
Query: 121 LGPDNTSVPTA-KFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179
+GPD + + A +G+++++ + +W A I+QR+ + ++ A + T+L
Sbjct: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVA-QITQRFYEAEEYAEEFRTYLE 182
Query: 180 FSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG 239
C LR +LE G+ L+ +PP + P S + L C A FYP E+ L + R+G
Sbjct: 183 GECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDG 242
Query: 240 --LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSS 297
T + P DG+F +++ V G+E Y C VQH GL QPL + E + +
Sbjct: 243 EEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPT 302
Query: 298 VLVVGIVIGVLLLTAAAVG---GALLWRRMRS 326
+ +VGIV G+++L A G A++WR+ S
Sbjct: 303 IPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSS 334
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 139 bits (349), Expect = 5e-33
Identities = 99/332 (29%), Positives = 164/332 (49%), Gaps = 22/332 (6%)
Query: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNS--LRG 66
LL LL G+L A SH S+ Y T+VS P G P F G++ Q++ ++S
Sbjct: 9 LLLLLSGALALTQTWAGSH-SMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQ 67
Query: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120
EP W+ E + YW++ET +++ + + L G G +T+Q + GC+
Sbjct: 68 RMEPRAPWI-EQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYGCD 126
Query: 121 LGPDNTSVPTAKF-ALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179
+G D + + A +G++++ + +W A ++W+ +A +L
Sbjct: 127 VGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLR-AYLD 185
Query: 180 FSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG 239
+C LR +LE G+ L+ +PP + P S + L C A FYP E+ L + R+G
Sbjct: 186 GTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDG 245
Query: 240 --LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSS 297
T + P DG+F +++ V SG+E Y C VQH GL +PL + E ++ +
Sbjct: 246 EDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPT 305
Query: 298 VLVVGIVIGVLLLTA---AAVGGALLWRRMRS 326
+ +VGI+ G++LL A AV A++WRR S
Sbjct: 306 IPIVGIIAGLVLLGAVITGAVVAAVMWRRKSS 337
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 130 bits (327), Expect = 2e-30
Identities = 100/334 (29%), Positives = 160/334 (47%), Gaps = 26/334 (7%)
Query: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66
L LL G+L A SH S+ Y AVS P G P F G++ Q++ ++S
Sbjct: 9 LFLLLSGALTLTETWAGSH-SMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSACP 67
Query: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLGCE 120
EP WV E + YWE+ET + + + + L G +TLQ ++GC+
Sbjct: 68 RMEPRAPWV-EQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIGCD 126
Query: 121 LGPDNTSVPT-AKFALNGEEFM--NFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177
LG D + ++A +G++++ N DL+ T A IS+R + A + +
Sbjct: 127 LGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADT---AAQISKRKCEAANVAEQRRAY 183
Query: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
L +C L +LE G+ L+ +PP + P + L C A FYP E+ L + R
Sbjct: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
Query: 238 NG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295
+G + P DG+F +++ V SG+E Y C VQH GL +PL + + +
Sbjct: 244 DGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSL 303
Query: 296 SSVLVVGIVIGVLLLTAAAVG---GALLWRRMRS 326
++ ++GIV G+++L A G A+LWR+ S
Sbjct: 304 PTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 127 bits (318), Expect = 2e-29
Identities = 94/327 (28%), Positives = 152/327 (46%), Gaps = 15/327 (4%)
Query: 4 PRPQPWALGLLLF---LLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
PR +P L L+L +L G L SH SL Y S G F G++ Q ++
Sbjct: 3 PRARPALLLLMLLQTAVLQGRL-LRSH-SLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL-----GGKGPYTLQG 115
Y+ EP WV S W + + L+ + +F F + K +TLQ
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Query: 116 LLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKEL 175
+LGCE+ DN++ K+ +G++ + F W P A W++ A +
Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
Query: 176 TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRF 235
+L CP +L++ LE GRG L+ + PP +++ +S + L C A ++YP + +++
Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALNYYPQNITMKW 239
Query: 236 LRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELES 292
L++ + D PN DG++ +L V G+E Y C V+H GL QPL V E
Sbjct: 240 LKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE- 298
Query: 293 PAKSSVLVVGIVIGVLLLTAAAVGGAL 319
P+ S LV+G++ G+ + G L
Sbjct: 299 PSPSGTLVIGVISGIAVFVVILFIGIL 325
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 122 bits (307), Expect = 4e-28
Identities = 84/298 (28%), Positives = 141/298 (47%), Gaps = 13/298 (4%)
Query: 5 RPQPWALGLLLFLLPG--SLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYN 62
R P L LLL L P + SL Y T +S PAF G L Q+ YN
Sbjct: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
Query: 63 SLRGEAEPCGAWVWENQVSWY--WEKETTDLRIKEKLFLEAFKAL-----GGKGPYTLQG 115
S +++P G W QV W++++ + +E +F+E K + G + LQG
Sbjct: 63 SKDRKSQPMGLW---RQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQG 119
Query: 116 LLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKEL 175
GCE+ + +S K+ +G++++ F+ + W P A Q+W+ + +
Sbjct: 120 RFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAK 179
Query: 176 TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRF 235
+L CP LR++L+ + L+ ++PPS+ + + + L C A+ FYP ++ + +
Sbjct: 180 AYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHW 239
Query: 236 LRNG-LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELES 292
R G + +GD N +G++ + + V D Y C VQH+ LAQPL V E+
Sbjct: 240 TRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEA 297
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 119 bits (297), Expect = 6e-27
Identities = 77/277 (27%), Positives = 132/277 (47%), Gaps = 10/277 (3%)
Query: 51 GWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL----- 105
G++ Q ++ Y+ EP WV S W + + L+ + +F F +
Sbjct: 28 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 87
Query: 106 GGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQ 165
K +TLQ +LGCE+ DN++ K+ +G++ + F W P A W+
Sbjct: 88 HSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWE 147
Query: 166 QQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFS 225
+ A + +L CP +L++ LE GRG L+ + PP +++ +S + L C A +
Sbjct: 148 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALN 206
Query: 226 FYPPELQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL 282
+YP + +++L++ + D PN DG++ +L V G+E Y C V+H GL
Sbjct: 207 YYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL 266
Query: 283 AQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
QPL V E P+ S LV+G++ G+ + G L
Sbjct: 267 DQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 302
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 116 bits (290), Expect = 4e-26
Identities = 91/327 (27%), Positives = 145/327 (44%), Gaps = 29/327 (8%)
Query: 4 PRPQPWALGLLLF---LLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
PR +P L L+L +L G L SH SL Y S G F G++ Q ++
Sbjct: 3 PRARPALLLLMLLQTAVLQGRL-LRSH-SLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL-----GGKGPYTLQG 115
Y+ EP WV S W + + L+ + +F F + K +TLQ
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Query: 116 LLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKEL 175
+LGCE+ DN++ K+ +G++ + F W P A W++ A +
Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
Query: 176 TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRF 235
+L CP +L++ LE GRG L+ + + L C A ++YP + +++
Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQNITMKW 225
Query: 236 LRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELES 292
L++ + D PN DG++ +L V G+E Y C V+H GL QPL V E
Sbjct: 226 LKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE- 284
Query: 293 PAKSSVLVVGIVIGVLLLTAAAVGGAL 319
P+ S LV+G++ G+ + G L
Sbjct: 285 PSPSGTLVIGVISGIAVFVVILFIGIL 311
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 109 bits (272), Expect = 4e-24
Identities = 64/212 (30%), Positives = 108/212 (50%), Gaps = 5/212 (2%)
Query: 111 YTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKA 170
+TLQ +LGCE+ DN++ K+ +G++ + F W P A W++
Sbjct: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIR 87
Query: 171 ANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPE 230
A + +L CP +L++ LE GRG L+ + PP +++ +S + L C A ++YP
Sbjct: 88 ARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALNYYPQN 146
Query: 231 LQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLR 287
+ +++L++ + D PN DG++ +L V G+E Y C V+H GL QPL
Sbjct: 147 ITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLI 206
Query: 288 VELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
V E P+ S LV+G++ G+ + G L
Sbjct: 207 VIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 237
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 98.6 bits (244), Expect = 8e-21
Identities = 61/212 (28%), Positives = 101/212 (47%), Gaps = 19/212 (8%)
Query: 111 YTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKA 170
+TLQ +LGCE+ DN++ K+ +G++ + F W P A W++
Sbjct: 28 HTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIR 87
Query: 171 ANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPE 230
A + +L CP +L++ LE GRG L+ + + L C A ++YP
Sbjct: 88 ARQNRAYLERDCPAQLQQLLELGRGVLDQQ---------------VTTLRCRALNYYPQN 132
Query: 231 LQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLR 287
+ +++L++ + D PN DG++ +L V G+E Y C V+H GL QPL
Sbjct: 133 ITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLI 192
Query: 288 VELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
V E P+ S LV+G++ G+ + G L
Sbjct: 193 VIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 223
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 88.2 bits (217), Expect = 1e-17
Identities = 72/287 (25%), Positives = 130/287 (45%), Gaps = 22/287 (7%)
Query: 13 LLLFLL------PGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG 66
+LLFL P + AE H SL Y+L +S F G L Q +L Y+ +
Sbjct: 6 VLLFLAVAFPFAPPAAAAEPH-SLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKR 64
Query: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGK--GPYTLQGLLGCELGPD 124
A+P G W + W+ ET DL + + + G ++LQ + CE+ D
Sbjct: 65 RAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHED 124
Query: 125 NTSVPTAKFALNGEEFMNFDLKQGTWGGDWPE-------ALAISQRWQQQDKAANKELTF 177
+++ + F +GE F++ +L+ T P+ A+ ++ W++
Sbjct: 125 SSTRGSRHFYYDGELFLSQNLE--TQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRA 182
Query: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
+ C +L+ +L+ G + PP + + S G +TC A SFYP + L + +
Sbjct: 183 MQADCLQKLQRYLKSGVA-IRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQ 241
Query: 238 NG--LAAGTGQ-GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG 281
+G L+ T Q GD P+ +G++ + ++ G+E + C ++H+G
Sbjct: 242 DGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 84.0 bits (206), Expect = 2e-16
Identities = 75/280 (26%), Positives = 131/280 (46%), Gaps = 13/280 (4%)
Query: 12 GLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPC 71
G+ F PG+ AE H SL Y+LT +S F L Q +L + + A+P
Sbjct: 12 GIFPFAPPGA-AAEPH-SLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQ 69
Query: 72 GAWVWENQVSWYWEKETTDL--RIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVP 129
G W + + W++ET DL K+ A +G ++LQ + CE+ DN++
Sbjct: 70 GQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRS 129
Query: 130 TAKFALNGEEFMNFDLKQGTW---GGDWPEALAISQRWQQQDKAANKELTF--LLFSCPH 184
+ F +GE F++ +L+ W + LA++ R ++ A + + + C
Sbjct: 130 SQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQ 189
Query: 185 RLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG--LAA 242
LR +L+ G L PP + + +S G +TC A FYP + L + ++G L+
Sbjct: 190 ELRRYLKSG-VVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSH 248
Query: 243 GTGQ-GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG 281
T Q GD P+ +G++ + + G+E + C ++H+G
Sbjct: 249 DTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSG 288
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 81.3 bits (199), Expect = 1e-15
Identities = 84/331 (25%), Positives = 146/331 (44%), Gaps = 33/331 (9%)
Query: 14 LLFLLPGSLGAESHLS-LLYHLTAVSSPAPGTPAFW----VSGWLGPQQYLSYNSLRGEA 68
LL +LPG A+ L +H+T ++S + W VSGWL Q +++S
Sbjct: 8 LLAVLPGDGNADGLKEPLSFHVTWIASFYNHS---WKQNLVSGWLSDLQTHTWDSNSSTI 64
Query: 69 EPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKA----LGGKGPYTLQGLLGCELGPD 124
W N + W++ T RI+ E + L + P+ +Q GCEL
Sbjct: 65 VFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSG 124
Query: 125 NTSVPTAKFALNGEEFMNFDLKQGTW-----GGDWPEALA--ISQRWQQQDKAANKELTF 177
S + A G +F++F + +W G+ + ++Q + D N
Sbjct: 125 KVSGSFLQLAYQGSDFVSF--QNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHN----L 178
Query: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCSAFSFYPPELQLRFL 236
L +CP + L+ G+ +L+ + P L PS PG L C FYP + + ++
Sbjct: 179 LSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWM 238
Query: 237 RNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL-AQPLRVELESPA 294
R GT +GD P++DG+++ ++L V +G+ C V+H+ L Q + + E +
Sbjct: 239 RGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHS 298
Query: 295 KSSVLVVGIVIGVLLLTAAAVGGALLWRRMR 325
+++ +++ +LLL G LW R R
Sbjct: 299 SVGFIILAVIVPLLLLI-----GLALWFRKR 324
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 76.3 bits (186), Expect = 4e-14
Identities = 76/285 (26%), Positives = 120/285 (42%), Gaps = 13/285 (4%)
Query: 52 WLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFL----EAFKALGG 107
WLG Q S+++ W WE R+ F E K L
Sbjct: 49 WLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRL 108
Query: 108 KGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGT-WGGDWPEALAISQRWQ- 165
P LQ GCE+ P N S A G++ ++F QGT W L ++ Q
Sbjct: 109 SYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSF---QGTSWEPTQEAPLWVNLAIQV 165
Query: 166 -QQDKAANKELTFLLF-SCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCS 222
QDK + + +LL +CP + LE G+ L+ + P L PS PG +L C
Sbjct: 166 LNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCH 225
Query: 223 AFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG 281
FYP + ++++R GT GD PN+D +++ ++L V +G+ C V+H+
Sbjct: 226 VSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
Query: 282 LAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRS 326
L V + +S+ ++ + + LL VG ++R S
Sbjct: 286 LEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTS 330
>gi|4502645 CD1B antigen precursor [Homo sapiens]
Length = 333
Score = 75.9 bits (185), Expect = 5e-14
Identities = 90/336 (26%), Positives = 147/336 (43%), Gaps = 37/336 (11%)
Query: 13 LLLFLLPGSLGAESHL---SLLYHLTAVSSPAPGTPAFWV----SGWLGPQQYLSYNSLR 65
LL L PG G H +H+ SS T W SGWL Q ++S
Sbjct: 8 LLAVLFPG--GNSEHAFQGPTSFHVIQTSSFTNST---WAQTQGSGWLDDLQIHGWDSDS 62
Query: 66 GEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGG----KGPYTLQGLL 117
G A W N + +KE +L ++++ F + G K P+ +QG+
Sbjct: 63 GTAIFLKPWSKGN----FSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIA 118
Query: 118 GCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQ---QDKAANKE 174
GCEL V + AL G +F++ +K + PE + +Q++ Q + +
Sbjct: 119 GCELHSGGAIVSFLRGALGGLDFLS--VKNASCVPS-PEGGSRAQKFCALIIQYQGIMET 175
Query: 175 LTFLLF-SCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCSAFSFYPPELQ 232
+ LL+ +CP L L G+ +L+ + P L + PS PG L C FYP +
Sbjct: 176 VRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVW 235
Query: 233 LRFLRNGL-AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL-AQPLRVEL 290
+ ++R GT GD PN++ +++ ++L V G+ C V+H+ L Q + +
Sbjct: 236 VMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYW 295
Query: 291 ESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRS 326
+P +V+ I++ LLL AL + R RS
Sbjct: 296 RNPTSIGSIVLAIIVPSLLLLLCL---ALWYMRRRS 328
>gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
Length = 388
Score = 73.6 bits (179), Expect = 3e-13
Identities = 83/304 (27%), Positives = 126/304 (41%), Gaps = 47/304 (15%)
Query: 13 LLLFLL------PGSLGAESHLSLLYHLTA---VSSPAPGTPAF----WV----SGWLGP 55
LLLFLL PG A YHL A +S T +F W SGWLG
Sbjct: 2 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
Query: 56 QQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGGKG-- 109
Q ++++ G W N + ++E +L+ +L+ +F +A G+
Sbjct: 62 LQTHGWDTVLGTIRFLKPWSHGN----FSKQELKNLQSLFQLYFHSFIQIVQASAGQFQL 117
Query: 110 --PYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQ 167
P+ +Q L GC + N A G +F++F G W + R Q
Sbjct: 118 EYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSFQ------GISWEPSPGAGIRAQNI 168
Query: 168 DKAANKEL-------TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVL 219
K N+ L + L +CP L +E G L+ K P L PS PG L
Sbjct: 169 CKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQL 228
Query: 220 TCSAFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ 278
C FYP + + ++R GT +GD PN+D +++ ++L V +G+ C V+
Sbjct: 229 VCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVK 288
Query: 279 HAGL 282
H+ L
Sbjct: 289 HSSL 292
>gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]
Length = 376
Score = 73.6 bits (179), Expect = 3e-13
Identities = 83/304 (27%), Positives = 126/304 (41%), Gaps = 47/304 (15%)
Query: 13 LLLFLL------PGSLGAESHLSLLYHLTA---VSSPAPGTPAF----WV----SGWLGP 55
LLLFLL PG A YHL A +S T +F W SGWLG
Sbjct: 2 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
Query: 56 QQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGGKG-- 109
Q ++++ G W N + ++E +L+ +L+ +F +A G+
Sbjct: 62 LQTHGWDTVLGTIRFLKPWSHGN----FSKQELKNLQSLFQLYFHSFIQIVQASAGQFQL 117
Query: 110 --PYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQ 167
P+ +Q L GC + N A G +F++F G W + R Q
Sbjct: 118 EYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSFQ------GISWEPSPGAGIRAQNI 168
Query: 168 DKAANKEL-------TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVL 219
K N+ L + L +CP L +E G L+ K P L PS PG L
Sbjct: 169 CKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQL 228
Query: 220 TCSAFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQ 278
C FYP + + ++R GT +GD PN+D +++ ++L V +G+ C V+
Sbjct: 229 VCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVK 288
Query: 279 HAGL 282
H+ L
Sbjct: 289 HSSL 292
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 68.6 bits (166), Expect = 9e-12
Identities = 60/202 (29%), Positives = 95/202 (47%), Gaps = 17/202 (8%)
Query: 14 LLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG-- 66
LL LL G+L A SH SL Y TAVS P G P + ++ Q+L ++S
Sbjct: 6 LLLLLSGALALTDTWAGSH-SLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAAIP 64
Query: 67 EAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL------GGKGPYTLQGLLGCE 120
EP WV E + YWE T + + A + L G +TLQG+ GC+
Sbjct: 65 RMEPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNGCD 123
Query: 121 LGPDNTSV-PTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLL 179
+GPD + + A +G+++++ + +W I+QR+ + ++ A + T+L
Sbjct: 124 MGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAA-DTVAQITQRFYEAEEYAEEFRTYLE 182
Query: 180 FSCPHRLREHLERGRGNLEWKE 201
C LR +LE G+ L+ E
Sbjct: 183 GECLELLRRYLENGKETLQRAE 204
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 65.5 bits (158), Expect = 7e-11
Identities = 77/291 (26%), Positives = 124/291 (42%), Gaps = 32/291 (10%)
Query: 13 LLLFLLPGSLGAES---HLSLLYHLTAVSSPAPGTPAFWV----SGWLGPQQYLSYNSLR 65
LL LLPG A++ H+S +H+ + S + W SGWL Q ++S
Sbjct: 8 LLALLLPGGDNADASQEHVS--FHVIQIFSFVNQS---WARGQGSGWLDELQTHGWDSES 62
Query: 66 GEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFL--------EAFKALGGKGPYTLQGLL 117
G W N + +E +DL + + +L + K P+ +Q
Sbjct: 63 GTIIFLHNWSKGN----FSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKA 118
Query: 118 GCELGPDNTSVPTAKFALNGEEFMNFDLKQGTW---GGDWPEALAISQRWQQQDKAANKE 174
GCEL + + A NG + ++F + TW G A ++ Q + +
Sbjct: 119 GCELHSGKSPEGFFQVAFNGLDLLSF--QNTTWVPSPGCGSLAQSVCHLLNHQYEGVTET 176
Query: 175 LTFLLFS-CPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCSAFSFYPPELQ 232
+ L+ S CP L L+ G+ + + P L +RPS G +L C A FYP +
Sbjct: 177 VYNLIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVW 236
Query: 233 LRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL 282
+ ++RN GT GD PN+DG+++ L V S + C V+H+ L
Sbjct: 237 VTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSL 287
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 64.3 bits (155), Expect = 2e-10
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 5/123 (4%)
Query: 200 KEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQ---GDFGPNSDGS 256
K PP +++ +S + L C A ++YP + +++L++ + D PN DG+
Sbjct: 113 KVPPLVKVTHHVTS-SVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 171
Query: 257 FHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVG 316
+ +L V G+E Y C V+H GL QPL V E P+ S LV+G++ G+ +
Sbjct: 172 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFI 230
Query: 317 GAL 319
G L
Sbjct: 231 GIL 233
Score = 28.9 bits (63), Expect = 7.6
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 5/102 (4%)
Query: 4 PRPQPWALGLLLF---LLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
PR +P L L+L +L G L SH SL Y S G F G++ Q ++
Sbjct: 3 PRARPALLLLMLLQTAVLQGRL-LRSH-SLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF 102
Y+ EP WV S W + + L+ + +F F
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDF 102
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 63.2 bits (152), Expect = 4e-10
Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 5/121 (4%)
Query: 202 PPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQ---GDFGPNSDGSFH 258
PP +++ +S + L C A ++YP + +++L++ + D PN DG++
Sbjct: 27 PPLVKVTHHVTS-SVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 259 ASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGA 318
+L V G+E Y C V+H GL QPL V E P+ S LV+G++ G+ + G
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGI 144
Query: 319 L 319
L
Sbjct: 145 L 145
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 62.0 bits (149), Expect = 8e-10
Identities = 34/106 (32%), Positives = 55/106 (51%), Gaps = 4/106 (3%)
Query: 217 SVLTCSAFSFYPPELQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHY 273
+ L C A ++YP + +++L++ + D PN DG++ +L V G+E Y
Sbjct: 115 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 174
Query: 274 CCIVQHAGLAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
C V+H GL QPL V E P+ S LV+G++ G+ + G L
Sbjct: 175 TCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 219
Score = 28.9 bits (63), Expect = 7.6
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 5/102 (4%)
Query: 4 PRPQPWALGLLLF---LLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
PR +P L L+L +L G L SH SL Y S G F G++ Q ++
Sbjct: 3 PRARPALLLLMLLQTAVLQGRL-LRSH-SLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF 102
Y+ EP WV S W + + L+ + +F F
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDF 102
>gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]
Length = 290
Score = 61.2 bits (147), Expect = 1e-09
Identities = 79/285 (27%), Positives = 114/285 (40%), Gaps = 50/285 (17%)
Query: 13 LLLFLL------PGSLGAESHLSLLYHLTA---VSSPAPGTPAF----WV----SGWLGP 55
LLLFLL PG A YHL A +S T +F W SGWLG
Sbjct: 2 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD 61
Query: 56 QQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAF----KALGGKG-- 109
Q ++++ G W N + ++E +L+ +L+ +F +A G+
Sbjct: 62 LQTHGWDTVLGTIRFLKPWSHGN----FSKQELKNLQSLFQLYFHSFIQIVQASAGQFQL 117
Query: 110 --PYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQ 167
P+ +Q L GC + N A G +F++F G W + R Q
Sbjct: 118 EYPFEIQILAGCRM---NAPQIFLNMAYQGSDFLSFQ------GISWEPSPGAGIRAQNI 168
Query: 168 DKAANKEL-------TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVL 219
K N+ L + L +CP L +E G L+ K P L PS PG L
Sbjct: 169 CKVLNRYLDIKEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQL 228
Query: 220 TCSAFSFYPPELQLRFLRNGL-AAGTGQGDFGPNSDGS---FHAS 260
C FYP + + ++R GT +GD PN+D + FH S
Sbjct: 229 VCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWWIFHLS 273
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,225,303
Number of Sequences: 37866
Number of extensions: 890570
Number of successful extensions: 2178
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1968
Number of HSP's gapped (non-prelim): 131
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.