Search of human proteins with 4557699

Search of human proteins with 4557699

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557699 keratin 12 [Homo sapiens]
         (494 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557699 keratin 12 [Homo sapiens]                                  952   0.0  
gi|195972866 keratin 10 [Homo sapiens]                                487   e-138
gi|192807292 keratin 24 [Homo sapiens]                                486   e-137
gi|24430190 keratin 15 [Homo sapiens]                                 473   e-133
gi|24430192 keratin 16 [Homo sapiens]                                 469   e-132
gi|15431310 keratin 14 [Homo sapiens]                                 468   e-132
gi|4557701 keratin 17 [Homo sapiens]                                  465   e-131
gi|131412225 keratin 13 isoform a [Homo sapiens]                      463   e-130
gi|131412228 keratin 13 isoform b [Homo sapiens]                      458   e-129
gi|153945736 keratin 27 [Homo sapiens]                                447   e-125
gi|114431246 keratin 25D [Homo sapiens]                               439   e-123
gi|24234699 keratin 19 [Homo sapiens]                                 432   e-121
gi|31559829 keratin 25 [Homo sapiens]                                 420   e-117
gi|55956899 keratin 9 [Homo sapiens]                                  400   e-111
gi|31559815 keratin 26 [Homo sapiens]                                 395   e-110
gi|27894337 keratin 20 [Homo sapiens]                                 360   1e-99
gi|4504927 keratin 36 [Homo sapiens]                                  350   2e-96
gi|94538345 keratin 35 [Homo sapiens]                                 348   8e-96
gi|14917117 keratin 33A [Homo sapiens]                                331   8e-91
gi|116488398 keratin 32 [Homo sapiens]                                330   1e-90
gi|14917115 keratin 31 [Homo sapiens]                                 330   2e-90
gi|10337581 type I hair keratin 3B [Homo sapiens]                     324   1e-88
gi|27894339 keratin 23 [Homo sapiens]                                 319   4e-87
gi|14917119 keratin 34 [Homo sapiens]                                 315   5e-86
gi|40354195 keratin 18 [Homo sapiens]                                 303   3e-82
gi|4557888 keratin 18 [Homo sapiens]                                  303   3e-82
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  297   2e-80
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  283   3e-76
gi|15431318 keratin 38 [Homo sapiens]                                 281   1e-75
gi|55770882 keratin 37 [Homo sapiens]                                 281   1e-75

>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  952 bits (2461), Expect = 0.0
 Identities = 494/494 (100%), Positives = 494/494 (100%)

Query: 1   MDLSNNTMSLSVRTPGLSRRLSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAA 60
           MDLSNNTMSLSVRTPGLSRRLSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAA
Sbjct: 1   MDLSNNTMSLSVRTPGLSRRLSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAA 60

Query: 61  SMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGL 120
           SMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGL
Sbjct: 61  SMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGL 120

Query: 121 LSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYY 180
           LSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYY
Sbjct: 121 LSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYY 180

Query: 181 PLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLD 240
           PLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLD
Sbjct: 181 PLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLD 240

Query: 241 ELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLND 300
           ELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLND
Sbjct: 241 ELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLND 300

Query: 301 MRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQ 360
           MRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQ
Sbjct: 301 MRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQ 360

Query: 361 SQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKA 420
           SQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKA
Sbjct: 361 SQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKA 420

Query: 421 RLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNG 480
           RLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNG
Sbjct: 421 RLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNG 480

Query: 481 EVVSSQVQEIEELM 494
           EVVSSQVQEIEELM
Sbjct: 481 EVVSSQVQEIEELM 494


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  487 bits (1254), Expect = e-138
 Identities = 263/432 (60%), Positives = 314/432 (72%), Gaps = 12/432 (2%)

Query: 21  LSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASM-FGSSSGFGGGS--GSSM 77
           +SS  +      +       G+ G +F  G+S GG F  +S  +G   GFGGGS  GS  
Sbjct: 31  VSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYG 90

Query: 78  AGGLGAGYGRALGGGSFGGL--------GMGFGGSPGGGSLGILSGNDGGLLSGSEKETM 129
           +   G  YG + GGGSFGG         G GFGG   GG  G   G DGGLLSG+EK TM
Sbjct: 91  SSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEKVTM 150

Query: 130 QNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNK 189
           QNLNDRLASYLDKVRALEE+N ELE KI+EWYE  G  +      DYSKYY  I+DL+N+
Sbjct: 151 QNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGN-SHQGEPRDYSKYYKTIDDLKNQ 209

Query: 190 IISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDL 249
           I++ +  NA +LLQIDNARLAA+DFR+KYENE+ALRQ VEADINGLRRVLDELTLT+ DL
Sbjct: 210 ILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADL 269

Query: 250 EMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIA 309
           EMQIESL EELAY+KKNHE+E++  R    G+V+VEM+AAPGVDLT+LLN+MR+QYE +A
Sbjct: 270 EMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLA 329

Query: 310 EQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSL 369
           EQNRKDAEAWF EKS EL  EI  N EQ+ S KSE+T+LRR  Q LEIELQSQLA+K+SL
Sbjct: 330 EQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSL 389

Query: 370 EDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETY 429
           E SLAE EG YC QLSQ+Q  IS LE QL Q+RA+ E QN ++Q+LL++K RLE EI+TY
Sbjct: 390 EASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTY 449

Query: 430 RRLLDGEAQGDG 441
           R LL+GE    G
Sbjct: 450 RSLLEGEGSSGG 461



 Score = 72.4 bits (176), Expect = 9e-13
 Identities = 43/97 (44%), Positives = 48/97 (49%), Gaps = 1/97 (1%)

Query: 32  GMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGG 91
           G  +S  GS  GG   G G S GGG+   S  G SSG G G GSS +GG G       GG
Sbjct: 474 GGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSS-SGGHGGSSSGGYGG 532

Query: 92  GSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKET 128
           GS GG G G+GG   GG      G  GG  SG  K +
Sbjct: 533 GSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSS 569



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 43/93 (46%), Positives = 45/93 (48%), Gaps = 11/93 (11%)

Query: 32  GMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRAL-- 89
           G    S G GYGG + G G S GGG       G SSG G G GSS  G  G GYG     
Sbjct: 463 GRGGGSFGGGYGGGSSG-GGSSGGGHGGGH--GGSSGGGYGGGSSGGGSSGGGYGGGSSS 519

Query: 90  ---GGGSFGGLGMGFGGSPGGGSLGILSGNDGG 119
              GG S GG G   GGS GGG  G   G+ GG
Sbjct: 520 GGHGGSSSGGYG---GGSSGGGGGGYGGGSSGG 549



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 42/97 (43%), Positives = 46/97 (47%), Gaps = 7/97 (7%)

Query: 32  GMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGG 91
           G    S G GYGG + G G S GGG+   S   SS G GG S     GG   G G   GG
Sbjct: 489 GGHGGSSGGGYGGGSSG-GGSSGGGYGGGS---SSGGHGGSSSGGYGGGSSGGGGGGYGG 544

Query: 92  GSFGGLGMGFGGSPGGGSL--GILSGNDGGLLSGSEK 126
           GS GG G   GG  GGGS   G  S + G +   S K
Sbjct: 545 GSSGG-GSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 35/76 (46%), Positives = 39/76 (51%), Gaps = 2/76 (2%)

Query: 48  GFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGG 107
           G G+S GGG    S FG   G G   G S  GG G G+G + GGG +GG   G G S GG
Sbjct: 455 GEGSSGGGGRGGGS-FGGGYGGGSSGGGSSGGGHGGGHGGSSGGG-YGGGSSGGGSSGGG 512

Query: 108 GSLGILSGNDGGLLSG 123
              G  SG  GG  SG
Sbjct: 513 YGGGSSSGGHGGSSSG 528



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 3/69 (4%)

Query: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGR 87
           G   G    S   GYGG + G G   GGG+   S  G SS  GG  G S +GG  +    
Sbjct: 516 GSSSGGHGGSSSGGYGGGSSGGG---GGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572

Query: 88  ALGGGSFGG 96
           ++G  S  G
Sbjct: 573 SVGESSSKG 581



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 23/48 (47%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 76  SMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSG 123
           S+  G G+  G   GGGSFGG G G G S GG S G   G  GG   G
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGG-GYGGGSSGGGSSGGGHGGGHGGSSGG 497


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  486 bits (1250), Expect = e-137
 Identities = 280/524 (53%), Positives = 360/524 (68%), Gaps = 57/524 (10%)

Query: 22  SSQSVIGRPRGMSASSVGSGYGGSAFGFGASCG----------GGFSAASMFGSSSG--- 68
           SS++   R  G S++ V +G  GS+F  G+ CG          GG S+ S+ G SSG   
Sbjct: 4   SSRASSSRAGGSSSARVSAG--GSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFG 61

Query: 69  --FGGGSGS-SMAGGLG--AGYGRALGGG-SFGGL-----GMGFGGSP------------ 105
             FGGG GS S+ GG G  +G G   GGG SFGG+     G GF GS             
Sbjct: 62  GSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYS 121

Query: 106 -GGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETR 164
            GGG  G     DGGL SG EK+TMQNLNDRLA+YLDKVRALEEANT+LENKI+EWY+  
Sbjct: 122 YGGGMGG--GVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKY 179

Query: 165 GTGTAD-ASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELA 223
           G G+ D  S  DYSKYY +IEDLRN+II+A++ NA ++L IDNARLAA+DFR+KYENEL 
Sbjct: 180 GPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELC 239

Query: 224 LRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVS 283
           LRQ VEADINGLR+VLD+LT+TR+DLEMQIES  EELAY++KNHE+E+++ +    GEV+
Sbjct: 240 LRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVT 299

Query: 284 VEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKS 343
           VEM+AAPG DLT+LLNDMRAQYE +AEQNR++AE  F ++S  L+ +IST+     S+K+
Sbjct: 300 VEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKN 359

Query: 344 EVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRA 403
           E+T+L+R  Q LEIELQSQLAMK SLE +LA+ E  Y AQLS++Q  IS LE ++ Q+  
Sbjct: 360 EITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWG 419

Query: 404 DAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEE--------------SLFVT 449
           + + QN ++++LL++K RLE+EIETYRRLLDGE  G    E               L   
Sbjct: 420 ETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSG 479

Query: 450 DSKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEIEEL 493
           DS+S    +   +D +KTR  KT+V+E+V+G+VVSSQV  I E+
Sbjct: 480 DSRS-GSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQVSSISEV 522


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  473 bits (1216), Expect = e-133
 Identities = 263/467 (56%), Positives = 331/467 (70%), Gaps = 30/467 (6%)

Query: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGG---FSAASMFGSSSGFGGGSGSSM-AGGLGA 83
           G  RG S  + G G+GG +     S GGG    SA+S    SSG GGG G  M   G G 
Sbjct: 16  GSTRGGSLLAGGGGFGGGSL----SGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGG 71

Query: 84  GYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKV 143
           G G   GGG  GG+G GFGG  GGG        DGGLLSG+EK TMQNLNDRLASYLDKV
Sbjct: 72  GAGSVFGGGFGGGVGGGFGGGFGGG--------DGGLLSGNEKITMQNLNDRLASYLDKV 123

Query: 144 RALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQ 203
           RALEEAN +LE KI +WY+ +   T  + + DYS+Y+  IE+LR+KI++ +I N++++L+
Sbjct: 124 RALEEANADLEVKIHDWYQKQ---TPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILE 180

Query: 204 IDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYM 263
           IDNARLAA+DFR+KYENELALRQGVEADINGLRRVLDELTL RTDLEMQIE LNEELAY+
Sbjct: 181 IDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYL 240

Query: 264 KKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEK 323
           KKNHE+E++ F     G+V+VEMDAAPGVDLTR+L +MR QYE +AE+NR+D EAWF  K
Sbjct: 241 KKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSK 300

Query: 324 SGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQ 383
           + EL KE+++NTE +Q+SK+E+TDLRR  Q LEIELQSQL+MK  LE+SLAE E  Y  Q
Sbjct: 301 TEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQ 360

Query: 384 LSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLE 443
           L Q+Q LI  LEAQL ++R + E QN +++ LL++K RLE EI TYR LL+G+   D   
Sbjct: 361 LQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQ---DAKM 417

Query: 444 ESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEI 490
             + + ++ S    + S+            V+E V+G+VVSS  +EI
Sbjct: 418 AGIGIREASSGGGGSSSN--------FHINVEESVDGQVVSSHKREI 456


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  469 bits (1206), Expect = e-132
 Identities = 257/445 (57%), Positives = 317/445 (71%), Gaps = 15/445 (3%)

Query: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGG--SGSSMAGGLGAGY 85
           G  R  S  + GS    S +G G S    FS+    G   G+GGG  S SS   G G GY
Sbjct: 27  GSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGY 86

Query: 86  GRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRA 145
           G  LG G  GGLG GFGG   GG          GLL GSEK TMQNLNDRLASYLDKVRA
Sbjct: 87  GGGLGAGFGGGLGAGFGGGFAGGD---------GLLVGSEKVTMQNLNDRLASYLDKVRA 137

Query: 146 LEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQID 205
           LEEAN +LE KIR+WY+ +      +   DYS Y+  IEDLRNKII+A+I NAQ +LQID
Sbjct: 138 LEEANADLEVKIRDWYQRQ----RPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQID 193

Query: 206 NARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKK 265
           NARLAA+DFR KYE+ELALRQ VEAD+NGLRRVLDELTL RTDLEMQIE L EELAY++K
Sbjct: 194 NARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRK 253

Query: 266 NHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSG 325
           NHE+E+ + R    G+V+VEMDAAPGVDL+R+LN+MR QYE +AE+NR+DAE WF+ K+ 
Sbjct: 254 NHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTE 313

Query: 326 ELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLS 385
           EL KE+++N+E +QSS+SEVT+LRR  Q LEIELQSQL+MK SLE+SL E +G YC QLS
Sbjct: 314 ELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLS 373

Query: 386 QVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEES 445
           Q+Q LI ++E QL Q+R + E+Q+ ++Q LL+VK RLE EI TYRRLL+GE      +++
Sbjct: 374 QIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQA 433

Query: 446 LFVTDSKSQAQSTDSSKDPTKTRKI 470
              + S  +  ++ SS    +TR I
Sbjct: 434 SGQSYSSREVFTSSSSSSSRQTRPI 458


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  468 bits (1205), Expect = e-132
 Identities = 261/462 (56%), Positives = 326/462 (70%), Gaps = 23/462 (4%)

Query: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGG-FSAASMFGSSSGFGGGSGSSMAGGLGAGYG 86
           G  R  S  + GS    S +G G S     FS+   +G   G+GGG  SS +   G+G+G
Sbjct: 27  GSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSS-SSSFGSGFG 85

Query: 87  RALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRAL 146
              GGG   GLG GFGG   GG          GLL GSEK TMQNLNDRLASYLDKVRAL
Sbjct: 86  GGYGGGLGAGLGGGFGGGFAGGD---------GLLVGSEKVTMQNLNDRLASYLDKVRAL 136

Query: 147 EEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDN 206
           EEAN +LE KIR+WY+ +      A   DYS Y+  IEDLRNKI++A++ NA +LLQIDN
Sbjct: 137 EEANADLEVKIRDWYQRQ----RPAEIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDN 192

Query: 207 ARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKN 266
           ARLAA+DFR KYE EL LR  VEADINGLRRVLDELTL R DLEMQIESL EELAY+KKN
Sbjct: 193 ARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKN 252

Query: 267 HEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGE 326
           HE+E+ + R    G+V+VEMDAAPGVDL+R+LN+MR QYE +AE+NRKDAE WF  K+ E
Sbjct: 253 HEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEE 312

Query: 327 LRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQ 386
           L +E++TN+E +QS KSE+++LRR  QNLEIELQSQL+MK SLE+SL E +G YC QL+Q
Sbjct: 313 LNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQ 372

Query: 387 VQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESL 446
           +Q++I ++E QL Q+R + E+QN +++ LL+VK RLE EI TYRRLL+GE     L  S 
Sbjct: 373 IQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGE--DAHLSSSQ 430

Query: 447 FVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQ 488
           F + S+S    T SS      R+I+T V ++ +G+VVS+  Q
Sbjct: 431 FSSGSQSSRDVTSSS------RQIRTKVMDVHDGKVVSTHEQ 466


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  465 bits (1197), Expect = e-131
 Identities = 254/443 (57%), Positives = 319/443 (72%), Gaps = 35/443 (7%)

Query: 57  FSAASMFGSSSGFGGGSGSS---MAGGLGAGYGRALGGGSFGGLGMGFGGSP-------- 105
           F+++S    SSG GGGS  +   ++GGLGAG  R    GS GGLG   GGS         
Sbjct: 8   FTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL---GSAGGLGSTLGGSSYSSCYSFG 64

Query: 106 GGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRG 165
            GG  G   G   GLL+G EK TMQNLNDRLASYLDKVRALEEANTELE KIR+WY+ + 
Sbjct: 65  SGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQA 124

Query: 166 TGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALR 225
            G A     DYS+YY  IE+L+NKI++A++ NA +LLQIDNARLAA+DFR K+E E ALR
Sbjct: 125 PGPA----RDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALR 180

Query: 226 QGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVE 285
             VEADINGLRRVLDELTL R DLEMQIE+L EELAY+KKNHE+E+ + R    GE++VE
Sbjct: 181 LSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVE 240

Query: 286 MDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEV 345
           MDAAPGVDL+R+LN+MR QYE +AE+NRKDAE WF  K+ EL +E++TN+E +QS KSE+
Sbjct: 241 MDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEI 300

Query: 346 TDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADA 405
           ++LRR  Q LEIELQSQL+MK SLE +LAE E  YC QLSQ+Q LI ++E QL Q+R + 
Sbjct: 301 SELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEM 360

Query: 406 ERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPT 465
           E+QN +++ LL+VK RLE EI TYRRLL+GE                  A  T   K+P 
Sbjct: 361 EQQNQEYKILLDVKTRLEQEIATYRRLLEGE-----------------DAHLTQYKKEPV 403

Query: 466 KTRKIKTVVQEMVNGEVVSSQVQ 488
            TR+++T+V+E+ +G+V+SS+ Q
Sbjct: 404 TTRQVRTIVEEVQDGKVISSREQ 426


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  463 bits (1191), Expect = e-130
 Identities = 253/445 (56%), Positives = 321/445 (72%), Gaps = 19/445 (4%)

Query: 34  SASSVGSGYGGSAFGFGASCG----------GGFSAASMFGSSSGFGGGSGSSMAGGLGA 83
           S++S G G+GG +   G   G          GG +     G S GFGGG+GS    G G 
Sbjct: 8   SSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGS----GFGG 63

Query: 84  GYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKV 143
           GYG  LGGG  GGLG GFGG   GG +      DGGLL+G+EK TMQNLNDRLASYL+KV
Sbjct: 64  GYGGGLGGGYGGGLGGGFGGGFAGGFVDF-GACDGGLLTGNEKITMQNLNDRLASYLEKV 122

Query: 144 RALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQ 203
           RALEEAN +LE KIR+W+  +   + +    DYS YY  IE+LR+KI++A+I N +++L+
Sbjct: 123 RALEEANADLEVKIRDWHLKQSPASPER---DYSPYYKTIEELRDKILTATIENNRVILE 179

Query: 204 IDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYM 263
           IDNARLAA+DFR+KYENELALRQ VEADINGLRRVLDELTL++TDLEMQIESLNEELAYM
Sbjct: 180 IDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYM 239

Query: 264 KKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEK 323
           KKNHE+E++ F     G+V+VEMDA PG+DLTR+L +MR QYE +AE+NR+DAE WF  K
Sbjct: 240 KKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAK 299

Query: 324 SGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQ 383
           S EL KE+STNT  +Q+SK+E+T+LRR  Q LEIELQSQL+MK  LE+++AE E  Y  Q
Sbjct: 300 SAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQ 359

Query: 384 LSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDG-EAQGDGL 442
           L Q+Q LIS++EAQL ++R++ E QN +++ LL++K RLE EI TYR LL+G +A+  G 
Sbjct: 360 LQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGF 419

Query: 443 EESLFVTDSKSQAQSTDSSKDPTKT 467
             S      +S + +T SS   T T
Sbjct: 420 PSSAGSVSPRSTSVTTTSSASVTTT 444


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  458 bits (1179), Expect = e-129
 Identities = 244/413 (59%), Positives = 308/413 (74%), Gaps = 18/413 (4%)

Query: 34  SASSVGSGYGGSAFGFGASCG----------GGFSAASMFGSSSGFGGGSGSSMAGGLGA 83
           S++S G G+GG +   G   G          GG +     G S GFGGG+GS    G G 
Sbjct: 8   SSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGS----GFGG 63

Query: 84  GYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKV 143
           GYG  LGGG  GGLG GFGG   GG +      DGGLL+G+EK TMQNLNDRLASYL+KV
Sbjct: 64  GYGGGLGGGYGGGLGGGFGGGFAGGFVDF-GACDGGLLTGNEKITMQNLNDRLASYLEKV 122

Query: 144 RALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQ 203
           RALEEAN +LE KIR+W+  +   + +    DYS YY  IE+LR+KI++A+I N +++L+
Sbjct: 123 RALEEANADLEVKIRDWHLKQSPASPER---DYSPYYKTIEELRDKILTATIENNRVILE 179

Query: 204 IDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYM 263
           IDNARLAA+DFR+KYENELALRQ VEADINGLRRVLDELTL++TDLEMQIESLNEELAYM
Sbjct: 180 IDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYM 239

Query: 264 KKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEK 323
           KKNHE+E++ F     G+V+VEMDA PG+DLTR+L +MR QYE +AE+NR+DAE WF  K
Sbjct: 240 KKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAK 299

Query: 324 SGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQ 383
           S EL KE+STNT  +Q+SK+E+T+LRR  Q LEIELQSQL+MK  LE+++AE E  Y  Q
Sbjct: 300 SAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQ 359

Query: 384 LSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGE 436
           L Q+Q LIS++EAQL ++R++ E QN +++ LL++K RLE EI TYR LL+G+
Sbjct: 360 LQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQ 412


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  447 bits (1149), Expect = e-125
 Identities = 244/445 (54%), Positives = 322/445 (72%), Gaps = 18/445 (4%)

Query: 52  SCGGGFSAASMFGSSSGFGGGSGSSMA-GGLGAGYGRALGGGSFGGLGMGFGGSPGGGSL 110
           SCGG     S+  SS G G G+G++    G+G+G+  A GG S  G   G+GG  GGGS 
Sbjct: 14  SCGG---TGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAG---GYGGGLGGGSA 67

Query: 111 GI--LSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGT 168
                +GN+ GLLSG+EK TMQNLNDRLASYL+ VRALEEAN +LE KI+ WYE  G G+
Sbjct: 68  SCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGS 127

Query: 169 ADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGV 228
                 DYS+Y+P+I++L+N+IISA+  NA ++LQ DNARL A+DFR+K+ENELAL Q V
Sbjct: 128 CRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSV 187

Query: 229 EADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDA 288
           EADINGLRRVLDELTL RTDLE+Q+E+L+EELAY+KKNHE+E+++ +    G V+VEM+A
Sbjct: 188 EADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNA 247

Query: 289 APGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDL 348
           APGVDLT LLN+MRA+YE +AEQNR+DAEAWF EKS  L+++IS +     S+++E+ ++
Sbjct: 248 APGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEM 307

Query: 349 RRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQ 408
           +R  Q LEIELQS LA K SLE SL E E +YCAQL+Q+Q  I  LE QL QVR + E Q
Sbjct: 308 KRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQ 367

Query: 409 NVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTR 468
            +++++LL++K  LE EIETY  L+DGE   DG       + SK      + +KD +KT 
Sbjct: 368 KLEYEQLLDIKVHLEKEIETYCLLIDGE---DG-----SCSKSKGYGGPGNQTKDSSKTT 419

Query: 469 KIKTVVQEM-VNGEVVSSQVQEIEE 492
            +KTVV+E+   G+V+SS+V  +EE
Sbjct: 420 IVKTVVEEIDPRGKVLSSRVHTVEE 444


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  439 bits (1128), Expect = e-123
 Identities = 244/443 (55%), Positives = 311/443 (70%), Gaps = 18/443 (4%)

Query: 58  SAASMFGSSSGFGGGSGSSMAGGLGAG--YGRALGGGSFGGLGMGFGGSPGGGSLGI--- 112
           S A      +G  G +GSS  GG  AG  +  ALGGG    LG   GGS  GG+LG    
Sbjct: 16  SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGG----LGSVPGGSHAGGALGNAAC 71

Query: 113 --LSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTAD 170
              +G++GGLLSG+EK TMQNLNDRLASYLD VRALEEAN ELE KI+ WYE  G G+  
Sbjct: 72  IGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCR 131

Query: 171 ASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEA 230
               DYS+Y+  IEDL+NKIIS++  NA ++LQIDNARLAA+DFR+KYENEL L Q VEA
Sbjct: 132 GLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEA 191

Query: 231 DINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAP 290
           DINGLRRVLDELTL RTD E+Q ESL+EE+ Y+KKNHE+E+++ +    G V+VEM+AAP
Sbjct: 192 DINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAP 251

Query: 291 GVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRR 350
           GVDL  LLN+MRA+YE +AEQNRKDAEAWF EKS  L+++IS ++     ++S++T++RR
Sbjct: 252 GVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRR 311

Query: 351 AFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNV 410
             Q LEI+LQS +A K SLE SL E E +YC QL+Q+Q  I  LE QL QVR + E Q +
Sbjct: 312 TLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKL 371

Query: 411 DHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKI 470
           +++ LL+VK  LE EIETY RL+DG+        S   +         +SSKD +KT  +
Sbjct: 372 EYEHLLDVKVHLEKEIETYCRLIDGDG------NSCSKSKGFGSGSPGNSSKDLSKTTLV 425

Query: 471 KTVVQEM-VNGEVVSSQVQEIEE 492
           KTVV+E+   G+V+SS++  IEE
Sbjct: 426 KTVVEELDQRGKVLSSRIHSIEE 448


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  432 bits (1110), Expect = e-121
 Identities = 238/406 (58%), Positives = 299/406 (73%), Gaps = 25/406 (6%)

Query: 31  RGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALG 90
           R  SA+S   G GG +  FG   G  F A S+ G S    GG G S++        R + 
Sbjct: 7   RQSSATSSFGGLGGGSVRFGP--GVAFRAPSIHGGS----GGRGVSVSSA------RFVS 54

Query: 91  GGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEAN 150
             S G  G G+GG        +L+ +DG LL+G+EK TMQNLNDRLASYLDKVRALE AN
Sbjct: 55  SSSSGAYGGGYGG--------VLTASDG-LLAGNEKLTMQNLNDRLASYLDKVRALEAAN 105

Query: 151 TELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLA 210
            ELE KIR+WY+ +G G +     DYS YY  I+DLR+KI+ A+I N++++LQIDNARLA
Sbjct: 106 GELEVKIRDWYQKQGPGPS----RDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLA 161

Query: 211 AEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDE 270
           A+DFR K+E E ALR  VEADINGLRRVLDELTL RTDLEMQIE L EELAY+KKNHE+E
Sbjct: 162 ADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEE 221

Query: 271 LQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKE 330
           + + R    G+VSVE+D+APG DL ++L+DMR+QYE +AEQNRKDAEAWF  ++ EL +E
Sbjct: 222 ISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNRE 281

Query: 331 ISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQL 390
           ++ +TEQLQ S+SEVTDLRR  Q LEIELQSQL+MK +LED+LAE E  + AQL+ +Q L
Sbjct: 282 VAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQAL 341

Query: 391 ISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGE 436
           IS +EAQL  VRAD+ERQN ++QRL+++K+RLE EI TYR LL+G+
Sbjct: 342 ISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQ 387


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  420 bits (1079), Expect = e-117
 Identities = 236/478 (49%), Positives = 318/478 (66%), Gaps = 35/478 (7%)

Query: 17  LSRRLSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSS 76
           +S RLSS S    PR  + S    G GG++FG G SCG                      
Sbjct: 1   MSLRLSSASRRSCPRPTTGSLRLYG-GGTSFGTGNSCG---------------------- 37

Query: 77  MAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRL 136
              G+G+G+  A GG S GG   G GG+P  G     + N+ GLLSG+EK TMQNLNDRL
Sbjct: 38  -ISGIGSGFSSAFGGSSSGG-NTG-GGNPCAG----FTVNERGLLSGNEKVTMQNLNDRL 90

Query: 137 ASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIG 196
           ASYLD V ALEEAN +LE KI+ WYE  G G+      DYS+Y+P+I+DL+N+II+++  
Sbjct: 91  ASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTS 150

Query: 197 NAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESL 256
           NA  +LQIDNARL A+DFR+KYENELAL Q VEAD+NGLRRVLDE+TL RTDLE+Q E+L
Sbjct: 151 NANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETL 210

Query: 257 NEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDA 316
           +EE+ Y+KKNH++E+Q  +    G V+VEM+AAPGVDLT LLN+MRA+YE +AEQNR+DA
Sbjct: 211 SEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDA 270

Query: 317 EAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEA 376
           EAWF EKS  L+++IS +     S+++E+T+++R  Q LEIELQS LA K SLE SL E 
Sbjct: 271 EAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTET 330

Query: 377 EGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGE 436
           E +YCAQL+Q+Q  I  LE QL QVR + E Q +++++LL++K  LE EIETY  L+ G+
Sbjct: 331 ESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGD 390

Query: 437 AQGDG-LEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEM-VNGEVVSSQVQEIEE 492
              DG  +   + +            KDP K   +K V++E+    +++++++  +EE
Sbjct: 391 ---DGACKSGGYKSKDYGSGNVGSQVKDPAKAIVVKKVLEEVDQRSKILTTRLHSLEE 445


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  400 bits (1029), Expect = e-111
 Identities = 210/408 (51%), Positives = 278/408 (68%), Gaps = 23/408 (5%)

Query: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGR 87
           G   G SASS+G G+GG + GFG + GGG+S      SS GFGGG G    GG G GYG 
Sbjct: 76  GSGGGFSASSLGGGFGGGSRGFGGASGGGYS------SSGGFGGGFGGGSGGGFGGGYG- 128

Query: 88  ALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALE 147
                 FGG G GFGG  GGG        DGG+L+ +EK TMQ LN RLASYLDKV+ALE
Sbjct: 129 ----SGFGGFG-GFGGGAGGG--------DGGILTANEKSTMQELNSRLASYLDKVQALE 175

Query: 148 EANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNA 207
           EAN +LENKI++WY+ +G     A Q +YS YY  I+DL+++I+  ++GN + LL IDN 
Sbjct: 176 EANNDLENKIQDWYDKKGPA---AIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNT 232

Query: 208 RLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNH 267
           R+  +DFR+K+E E  LRQGV+ADINGLR+VLD LT+ ++DLEMQ E+L EEL  +KKNH
Sbjct: 233 RMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNH 292

Query: 268 EDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGEL 327
           ++E+        G+V+VE++ APG DLT+ LNDMR +YE +  +NRKD E  +  +  ++
Sbjct: 293 KEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQI 352

Query: 328 RKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQV 387
             E+S++ +++QSS  EVT LR   Q LEIELQSQL+ K +LE SL + +  YC QL  +
Sbjct: 353 EHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMI 412

Query: 388 QQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDG 435
           Q+ ISNLEAQ+  VR + E QN ++  LL++K RLE EIETY  LL+G
Sbjct: 413 QEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG 460



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 51/110 (46%), Positives = 54/110 (49%), Gaps = 13/110 (11%)

Query: 31  RGMSASSVGSGYG---GSAFGFGASCGGGFSAASMFGSSSGFGG--GSGSSMAGGLGAGY 85
           RG S  S G G G   GS  G+G   GGG S  S  G S G GG  G GS   GG G GY
Sbjct: 513 RGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGY 572

Query: 86  GRALG-----GGSFGGLGMGFGGSPGG--GSLGILSGNDGGLLSGSEKET 128
           G   G     GGS GG G GFGG  GG  G     SG+ GG   GS K +
Sbjct: 573 GGGSGSRGGSGGSHGG-GSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 45/110 (40%), Positives = 52/110 (47%), Gaps = 8/110 (7%)

Query: 16  GLSRRLSSQSVIGR-PRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSG 74
           GL  R  S    GR  RG S  S G G  G  +G G+   GG  +   +G  SG GGGSG
Sbjct: 474 GLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG--SGGSYGGGSGSGGGSG 531

Query: 75  SSMAGGLGAGYGRALGGGSFGGLGMGFGGSPG-----GGSLGILSGNDGG 119
               GG G G+    GGG  GG G  +GG  G     GG  G  SG+ GG
Sbjct: 532 GGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGG 581



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 45/101 (44%), Positives = 49/101 (48%), Gaps = 9/101 (8%)

Query: 31  RGMSASSVG----SGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYG 86
           RG S  S G     G GGS  G G+  G G  + S  GS   +GGGSGS   GG G GYG
Sbjct: 478 RGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGS--GGGSGGGYG 535

Query: 87  RALGGGSFGGLGMGFGGSPG---GGSLGILSGNDGGLLSGS 124
              GGG  GG G G  G  G   GG  G   G+ GG   GS
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGS 576



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 38/93 (40%), Positives = 41/93 (44%), Gaps = 9/93 (9%)

Query: 40  SGYGGSAFGFGASCGGGFSAASMFGSSSGFGGG-SGSSMAGGLGA--------GYGRALG 90
           SG G    G     GG +   S  GS   +GGG SG    GG G+        G G   G
Sbjct: 468 SGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSG 527

Query: 91  GGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSG 123
           GGS GG G G GG   GGS G  SG  GG   G
Sbjct: 528 GGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGG 560



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 39/93 (41%), Positives = 42/93 (45%), Gaps = 13/93 (13%)

Query: 44  GSAFGFGASCGGGFSAASMFGSSSGFG----GGSGSSM-AGGLGAGYGRALG-----GGS 93
           G    F +S  G        GS   +G    GGSG S   GG G GYG   G     GGS
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGS 519

Query: 94  FG---GLGMGFGGSPGGGSLGILSGNDGGLLSG 123
           +G   G G G GG  GGGS G  SG  GG  SG
Sbjct: 520 YGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG 552



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 34/84 (40%), Positives = 38/84 (45%), Gaps = 7/84 (8%)

Query: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAG--Y 85
           G   G S  S G   GGS   +G   G G  +   +G  SG  GGSG S  GG G G   
Sbjct: 537 GSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGES 596

Query: 86  GRALGGG-----SFGGLGMGFGGS 104
           G + GGG     S GG G G G S
Sbjct: 597 GGSYGGGEEASGSGGGYGGGSGKS 620



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 33/82 (40%), Positives = 37/82 (45%), Gaps = 5/82 (6%)

Query: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGR 87
           G   G S  S G+  GGS  G G+  G G  + S  GS    GGGSG    G  G  YG 
Sbjct: 545 GSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSG--FGGESGGSYG- 601

Query: 88  ALGGGSFGGLGMGFGGSPGGGS 109
             GG    G G G+GG  G  S
Sbjct: 602 --GGEEASGSGGGYGGGSGKSS 621



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 25/51 (49%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 75  SSMAGGLGAGYGRALGGGSFG-GLGMGFGGSPGGGSLGILSGNDGGLLSGS 124
           SS AG +G G GR   GGS+G G   G GGS GGG  G   G   G   GS
Sbjct: 467 SSGAGKIGLG-GRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGS 516


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  395 bits (1016), Expect = e-110
 Identities = 223/446 (50%), Positives = 299/446 (67%), Gaps = 10/446 (2%)

Query: 54  GGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGR------ALGGGSFGGLGMGFGGSPGG 107
           GG     S  GS    GGG+G  +AG +  G G        L G S GG     GG  G 
Sbjct: 7   GGSRRICSRTGSGRLSGGGTGF-VAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGS 65

Query: 108 GSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTG 167
           G+     GN+  LLSG+EK TMQNLNDRLASYLD V ALEEAN +LE KI+  YE    G
Sbjct: 66  GACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPG 125

Query: 168 TADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQG 227
           ++     DYS+Y+ +IEDL+ +I SA+I NA ++LQ DNARL A+DFR+KYENELAL   
Sbjct: 126 SSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHS 185

Query: 228 VEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMD 287
           VEAD +GLRRVLDELTL  TDLE+Q E+L+EEL Y+KK+HE+E++  +    G V+VEM+
Sbjct: 186 VEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMN 245

Query: 288 AAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTD 347
           A PGVDLT LLN+MRA+YE +AEQNRKDAEAWF E+S  L+++IS +     ++++E+T+
Sbjct: 246 ATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTE 305

Query: 348 LRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAER 407
           L+R  Q LEIELQS +A+K S E SLAE EG+YC QL Q+Q  I  +E QL Q+R + E 
Sbjct: 306 LKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEG 365

Query: 408 QNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKT 467
           Q +++++LL+VK  LE EI+ Y  LLDGE +    + + + +       S + +KD T+ 
Sbjct: 366 QKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKS--KSTCYKSKGYRPVNSGNQAKDSTEE 423

Query: 468 RKIKTVVQEMVN-GEVVSSQVQEIEE 492
             +KTVV+E+   G ++S +V  +EE
Sbjct: 424 TIVKTVVEELDQIGNLLSLRVHSVEE 449


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  360 bits (925), Expect = 1e-99
 Identities = 194/401 (48%), Positives = 281/401 (70%), Gaps = 15/401 (3%)

Query: 92  GSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANT 151
           G  GG G+    S    + G      G L  G+EK  MQNLNDRLASYL+KVR LE++N+
Sbjct: 37  GGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNS 96

Query: 152 ELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAA 211
           +LE +I++WYET     A  +  DYS YY  IE+LR++I  A + NA+ +LQIDNA+LAA
Sbjct: 97  KLEVQIKQWYETN----APRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAA 152

Query: 212 EDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDEL 271
           EDFR+KYE E  +R  VEAD+ GL +V D+LTL +TDLE+QIE LN++LA +KK H++E+
Sbjct: 153 EDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEV 212

Query: 272 QSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEI 331
                     V+VE+DAAPG++L  ++N+MR +YE +A++N ++A+  F  ++  L++++
Sbjct: 213 DGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQV 272

Query: 332 STNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLI 391
           + NTE+L+ ++ ++T+LRR  Q+LEIELQS L+MK+SLE +L E +  Y +QL+ +Q L+
Sbjct: 273 TVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLL 332

Query: 392 SNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDS 451
           S+LEAQL+Q+R++ ERQN ++  LL++K RLE EI TYRRLL+GE              +
Sbjct: 333 SSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGED-----------VKT 381

Query: 452 KSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEIEE 492
                ST   +D  KTRKIKTVVQE+V+G+VVSS+V+E+EE
Sbjct: 382 TEYQLSTLEERDIKKTRKIKTVVQEVVDGKVVSSEVKEVEE 422


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  350 bits (898), Expect = 2e-96
 Identities = 212/461 (45%), Positives = 284/461 (61%), Gaps = 32/461 (6%)

Query: 52  SCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGS---------FGGLGMGFG 102
           +C   FS  S+ G     GG S  S    +G+    +L G +           GLG    
Sbjct: 5   TCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLP 64

Query: 103 GS------PGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENK 156
           GS         G +G       G  +GSEKETMQ LNDRLA+YL+KVR LE  N ELE++
Sbjct: 65  GSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESR 124

Query: 157 IREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRM 216
           I+EWYE +          DY  Y+  IED + KI+     NA+L+LQIDNA+LAA+DFR 
Sbjct: 125 IQEWYEFQIPYICP----DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRT 180

Query: 217 KYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRV 276
           KYE EL+LRQ VEADINGLRR+LDELTL + DLE Q+ESL EEL  +KKNHE+E+   R 
Sbjct: 181 KYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRC 240

Query: 277 GGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTE 336
                ++VE+DAAP VDL ++L DMR QYE + E NR+D EAWF  ++ EL +++ +++E
Sbjct: 241 QLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSE 300

Query: 337 QLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEA 396
           QLQ  ++E+ +LRR    LEIELQ+Q +M+ SLE +LAE E  Y +QL+Q+Q LISN+EA
Sbjct: 301 QLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEA 360

Query: 397 QLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQ 456
           QL ++R D ERQN ++Q LL+VKARLE EI TYR LL+GE     L      T  K   +
Sbjct: 361 QLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGE--DCKLPPQPCATACKPVIR 418

Query: 457 -----------STDSSKDPTKTRKIKTVVQEMVNGEVVSSQ 486
                      S   +  P    +I+T+ +E+ +G+V+SS+
Sbjct: 419 VPSVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSR 459


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  348 bits (892), Expect = 8e-96
 Identities = 196/414 (47%), Positives = 275/414 (66%), Gaps = 20/414 (4%)

Query: 33  MSASSVGSGYG-GSAFGFGASCGGGFSAASMFGSSS----GFGGGSGSSMAGGLGAGYGR 87
           M++  + +G+  GS    G + GG    ++M+ SSS         + S  A  +G G   
Sbjct: 1   MASKCLKAGFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSS 60

Query: 88  ALGGGSFGGLGMGFGG-----SPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDK 142
                    L +  GG     S GGG  G       G+L+G+EKETMQ+LNDRLA YL+K
Sbjct: 61  YRATSCLPALCLPAGGFATSYSGGGGWFG------EGILTGNEKETMQSLNDRLAGYLEK 114

Query: 143 VRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLL 202
           VR LE+ N  LE++IREW E +          DY  Y+  IE+L+ K + +   NA+L++
Sbjct: 115 VRQLEQENASLESRIREWCEQQ----VPYMCPDYQSYFRTIEELQKKTLCSKAENARLVV 170

Query: 203 QIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAY 262
           +IDNA+LAA+DFR KYE E++LRQ VE+DINGLRR+LD+LTL ++DLE Q+ESL EEL  
Sbjct: 171 EIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLC 230

Query: 263 MKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIE 322
           +KKNHE+E+ S R      ++VE+DAAP VDL R+L +MR QYET+ E NR+DAE W   
Sbjct: 231 LKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDT 290

Query: 323 KSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCA 382
           +S EL +++ +++EQLQS ++E+ +LRR    LEIELQ+Q +M+ +LE +LAE E  Y +
Sbjct: 291 QSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSS 350

Query: 383 QLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGE 436
           QL+Q+Q +I+N+EAQL ++RAD ERQN ++Q LL+V+ARLE EI TYR LL+ E
Sbjct: 351 QLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESE 404


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  331 bits (849), Expect = 8e-91
 Identities = 173/318 (54%), Positives = 236/318 (74%), Gaps = 4/318 (1%)

Query: 119 GLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSK 178
           G  +GSEKETMQ LNDRLASYL+KVR LE  N ELEN IRE    R         + Y  
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE----RSQQQEPLVCASYQS 105

Query: 179 YYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRV 238
           Y+  IE+L+ KI+ +   NA+L++QIDNA+LA++DFR KYE EL+LRQ VE+DINGLRR+
Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165

Query: 239 LDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLL 298
           LDELTL R+DLE Q+ESL EEL  +K+NHE E+ + R      ++VE+DAAP VDL ++L
Sbjct: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225

Query: 299 NDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIE 358
           N+ R+QYE + E NR++ E WF  ++ EL K++ +++EQLQS ++E+ +LRR    LEIE
Sbjct: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 359 LQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNV 418
           LQ+Q  ++ SLE++L E+E  Y +QLSQVQ+LI+N+E+QL ++R+D ERQN ++Q LL+V
Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 419 KARLELEIETYRRLLDGE 436
           +ARLE EI TYR LL+ E
Sbjct: 346 RARLECEINTYRSLLESE 363


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  330 bits (847), Expect = 1e-90
 Identities = 173/329 (52%), Positives = 241/329 (73%), Gaps = 4/329 (1%)

Query: 108 GSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTG 167
           GS+G  S    G  +G+EKETMQ LNDRLASYL +VR LE+ N ELE++I+E   ++   
Sbjct: 79  GSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVL- 137

Query: 168 TADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQG 227
                  DY  ++  IE+L+ KI+     NA++++ IDNA+LAA+DFR KYE ELA+RQ 
Sbjct: 138 ---TMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQL 194

Query: 228 VEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMD 287
           VEADINGLRR+LD+LTL + DLE Q+ESL EEL  +KKNHE+E+ S R      +++E+D
Sbjct: 195 VEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVD 254

Query: 288 AAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTD 347
           AAP VDLTR+L +MR QYE + E NR+D E WF  +  EL ++++T++EQLQ+ +S++ D
Sbjct: 255 AAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIID 314

Query: 348 LRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAER 407
           LRR    LEIELQ+Q +++ SLE++L E+E  Y +QL+Q+Q +I+N+EAQL ++RAD ER
Sbjct: 315 LRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLER 374

Query: 408 QNVDHQRLLNVKARLELEIETYRRLLDGE 436
           QN ++Q LL+V+ARLE EI TYR LL+ E
Sbjct: 375 QNQEYQVLLDVRARLEGEINTYRSLLENE 403


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  330 bits (845), Expect = 2e-90
 Identities = 173/318 (54%), Positives = 232/318 (72%), Gaps = 4/318 (1%)

Query: 119 GLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSK 178
           G  +GSEKETMQ LNDRLASYL+KVR LE  N ELEN IRE    R           Y  
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE----RSQQQEPLLCPSYQS 105

Query: 179 YYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRV 238
           Y+  IE+L+ KI+     NA+L++QIDNA+LAA+DFR KY+ EL+LRQ VE+DINGLRR+
Sbjct: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165

Query: 239 LDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLL 298
           LDELTL ++DLE Q+ESL EEL  +K NHE E+ + R      ++VE+DAAP VDL R+L
Sbjct: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225

Query: 299 NDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIE 358
           N+ R+QYE + E NR++ E WF  ++ EL K++ +++EQLQS ++E+ +LRR    LEIE
Sbjct: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 359 LQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNV 418
           LQ+Q  ++ SLE++L E+E  Y +QLSQVQ LI+N+E+QL ++R+D ERQN ++Q LL+V
Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 419 KARLELEIETYRRLLDGE 436
           +ARLE EI TYR LL+ E
Sbjct: 346 RARLECEINTYRSLLESE 363


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  324 bits (830), Expect = 1e-88
 Identities = 171/318 (53%), Positives = 231/318 (72%), Gaps = 4/318 (1%)

Query: 119 GLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSK 178
           G  +GSEKETMQ LNDRLASYL+KVR LE  N ELEN IRE    R           Y  
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE----RSQQQEPLLCPSYQS 105

Query: 179 YYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRV 238
           Y+  IE+L+ KI+ +   NA+L++QIDNA+LAA+DFR KY+ E +LRQ VE+DIN LRR+
Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRI 165

Query: 239 LDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLL 298
           LDELTL R+DLE Q+ESL EEL  +K+NHE E+ + R      ++VE+DAAP VDL ++L
Sbjct: 166 LDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVL 225

Query: 299 NDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIE 358
           N+ R QYE + E NR++ E WF  ++ EL K++ +++EQLQS ++E+ +LRR    LEIE
Sbjct: 226 NETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 359 LQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNV 418
           LQ+Q  ++ SLE++L E+E  Y +QLSQVQ LI+N+E+QL ++R+D ERQN ++Q LL+V
Sbjct: 286 LQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 419 KARLELEIETYRRLLDGE 436
           +ARLE EI TYR LL+ E
Sbjct: 346 RARLECEINTYRSLLESE 363


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  319 bits (817), Expect = 4e-87
 Identities = 178/434 (41%), Positives = 266/434 (61%), Gaps = 25/434 (5%)

Query: 59  AASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDG 118
           +AS  G+  G+G       A  +  G G A    SF          P GGS G  SG   
Sbjct: 12  SASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSC----PPPGGSWG--SGRSS 65

Query: 119 GLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSK 178
            LL G+ K TMQNLNDRLASYL+KVRALEEAN +LE++I +W++ R  G    S+ DYS+
Sbjct: 66  PLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPG----SKKDYSQ 121

Query: 179 YYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRV 238
           Y   I  L+ +I+   + NAQ++L IDNAR+A +DF +KYENE + ++ +E ++ GLRR 
Sbjct: 122 YEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRT 181

Query: 239 LDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLL 298
           LD LT+  TDLE ++E + +EL  MKK+HE E++   V     V+V++D  P  DL ++L
Sbjct: 182 LDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVL 241

Query: 299 NDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIE 358
            DMR +YE I ++  +D + W+ E+S  + +E + +   +QS + ++ +L+R FQ LEI+
Sbjct: 242 EDMRQEYELIIKKKHRDLDTWYKEQSAAMSQE-AASPATVQSRQGDIHELKRTFQALEID 300

Query: 359 LQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNV 418
           LQ+Q + K +LE+ L+E +  Y  +L  +Q++IS+ E +L Q+R + ERQN ++Q LL +
Sbjct: 301 LQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGI 360

Query: 419 KARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMV 478
           K  LE EI TYRRLL+GE++G                + + SS   + T KIK + QE +
Sbjct: 361 KTHLEKEITTYRRLLEGESEG--------------TREESKSSMKVSATPKIKAITQETI 406

Query: 479 NGEVVSSQVQEIEE 492
           NG +V  QV EI++
Sbjct: 407 NGRLVLCQVNEIQK 420


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  315 bits (808), Expect = 5e-86
 Identities = 165/318 (51%), Positives = 228/318 (71%), Gaps = 4/318 (1%)

Query: 119 GLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSK 178
           G  +GSEKETMQ LNDRLASYL+KVR LE  N ELE  I+E    R           Y  
Sbjct: 92  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQE----RSQQQEPLLCPSYQS 147

Query: 179 YYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRV 238
           Y+  IE+L+ KI+ A   NA+L++ IDNA+LA++DFR KY+ E +LR  VE+DIN +RR+
Sbjct: 148 YFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRI 207

Query: 239 LDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLL 298
           LDELTL ++DLE Q+ESL EEL  +KKNHE+E+ + R      ++VE+D AP VDL ++L
Sbjct: 208 LDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVL 267

Query: 299 NDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIE 358
           N+ R+QYE + E NR++ E WF  ++ EL K++ +++EQLQS ++E+ +LRR    LEIE
Sbjct: 268 NETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIE 327

Query: 359 LQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNV 418
           LQ+Q  ++ SLE++L E+E  Y +QLSQVQ LI+N+E+QL ++R D ERQN ++Q LL+V
Sbjct: 328 LQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDV 387

Query: 419 KARLELEIETYRRLLDGE 436
           +ARLE EI TYR LL+ E
Sbjct: 388 RARLECEINTYRSLLESE 405


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  303 bits (775), Expect = 3e-82
 Identities = 181/431 (41%), Positives = 271/431 (62%), Gaps = 45/431 (10%)

Query: 58  SAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGND 117
           SAAS++  +    GGSGS ++      +    GG   GGL  G  G   G          
Sbjct: 31  SAASVYAGA----GGSGSRISVSRSTSFR---GGMGSGGLATGIAGGLAGM--------- 74

Query: 118 GGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYS 177
           GG+ +  EKETMQ+LNDRLASYLD+VR+LE  N  LE+KIRE  E +G    D     +S
Sbjct: 75  GGIQN--EKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVRD-----WS 127

Query: 178 KYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRR 237
            Y+ +IEDLR +I + ++ NA+++LQIDNARLAA+DFR+KYE ELA+RQ VE DI+GLR+
Sbjct: 128 HYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRK 187

Query: 238 VLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVG-GPGEVSVEMDAAPGVDLTR 296
           V+D+  +TR  LE +IE+L EEL +MKKNHE+E++  +       ++VE+DA    DL +
Sbjct: 188 VIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAK 247

Query: 297 LLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLE 356
           ++ D+RAQY+ +A +NR++ + ++ ++  E    ++T + ++ ++++ +T+LRR  Q+LE
Sbjct: 248 IMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLE 307

Query: 357 IELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLL 416
           I+L S   +K SLE+SL E E  Y  Q+ Q+  ++ +LE++L Q RA+ +RQ  +++ LL
Sbjct: 308 IDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALL 367

Query: 417 NVKARLELEIETYRRLL-DGE--AQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTV 473
           N+K +LE EI TYRRLL DGE    GD L       DS +  Q+             KT 
Sbjct: 368 NIKVKLEAEIATYRRLLEDGEDFNLGDAL-------DSSNSMQTIQ-----------KTT 409

Query: 474 VQEMVNGEVVS 484
            + +V+G+VVS
Sbjct: 410 TRRIVDGKVVS 420


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  303 bits (775), Expect = 3e-82
 Identities = 181/431 (41%), Positives = 271/431 (62%), Gaps = 45/431 (10%)

Query: 58  SAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGND 117
           SAAS++  +    GGSGS ++      +    GG   GGL  G  G   G          
Sbjct: 31  SAASVYAGA----GGSGSRISVSRSTSFR---GGMGSGGLATGIAGGLAGM--------- 74

Query: 118 GGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYS 177
           GG+ +  EKETMQ+LNDRLASYLD+VR+LE  N  LE+KIRE  E +G    D     +S
Sbjct: 75  GGIQN--EKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVRD-----WS 127

Query: 178 KYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRR 237
            Y+ +IEDLR +I + ++ NA+++LQIDNARLAA+DFR+KYE ELA+RQ VE DI+GLR+
Sbjct: 128 HYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRK 187

Query: 238 VLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVG-GPGEVSVEMDAAPGVDLTR 296
           V+D+  +TR  LE +IE+L EEL +MKKNHE+E++  +       ++VE+DA    DL +
Sbjct: 188 VIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAK 247

Query: 297 LLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLE 356
           ++ D+RAQY+ +A +NR++ + ++ ++  E    ++T + ++ ++++ +T+LRR  Q+LE
Sbjct: 248 IMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLE 307

Query: 357 IELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLL 416
           I+L S   +K SLE+SL E E  Y  Q+ Q+  ++ +LE++L Q RA+ +RQ  +++ LL
Sbjct: 308 IDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALL 367

Query: 417 NVKARLELEIETYRRLL-DGE--AQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTV 473
           N+K +LE EI TYRRLL DGE    GD L       DS +  Q+             KT 
Sbjct: 368 NIKVKLEAEIATYRRLLEDGEDFNLGDAL-------DSSNSMQTIQ-----------KTT 409

Query: 474 VQEMVNGEVVS 484
            + +V+G+VVS
Sbjct: 410 TRRIVDGKVVS 420


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  297 bits (760), Expect = 2e-80
 Identities = 157/320 (49%), Positives = 223/320 (69%), Gaps = 4/320 (1%)

Query: 117 DGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDY 176
           + G+ + +EKETMQ LNDRLASYL+KVR+LEE N ELE++I+E  E            DY
Sbjct: 81  EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQ----DIPMVCPDY 136

Query: 177 SKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLR 236
            +Y+  IEDL+ KI+     N++L +Q+DN +LA +DF+ KYE+EL+LRQ +EADI+ L 
Sbjct: 137 QRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLH 196

Query: 237 RVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTR 296
            +L+ELTL ++DLE  +ESL E+L  +KKNHE+E+   R      +SVE+D AP +DL R
Sbjct: 197 GILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNR 256

Query: 297 LLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLE 356
           +L++MR Q ET+   NR++AE W   ++ EL ++  ++ EQLQ  + E+ +L+R    LE
Sbjct: 257 VLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALE 316

Query: 357 IELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLL 416
           IELQ+Q ++ +SLE ++AE E  Y +QL+Q+Q LI NLE QL ++R D ERQN ++Q LL
Sbjct: 317 IELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLL 376

Query: 417 NVKARLELEIETYRRLLDGE 436
           +VKARLE EI TY  LLD E
Sbjct: 377 DVKARLEGEINTYWGLLDSE 396


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  283 bits (723), Expect = 3e-76
 Identities = 163/389 (41%), Positives = 235/389 (60%), Gaps = 28/389 (7%)

Query: 121 LSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYY 180
           ++ +EKETMQ LN+RLA+YL KVR LE  N ELE+KI+E               DY  YY
Sbjct: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQE----ESNKELPVLCPDYLSYY 147

Query: 181 PLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLD 240
             IE+L+ KI+     N++L+ QIDN +L A+D R KYE E++LRQ VE+D NGL+++L+
Sbjct: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207

Query: 241 ELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLND 300
            LTL + DLE Q++SL EEL  +K NH++E+ S +      + +E+ AAP  DL ++L +
Sbjct: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267

Query: 301 MRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQ 360
           MR QYE I E NRKD E WF  +  EL +++ T+++Q Q  + E+ +LRR+   LE+ELQ
Sbjct: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327

Query: 361 SQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKA 420
           +Q  M+ S E  L E E  Y A L+Q+Q LI NLEAQL ++R   ERQN +++ LL+VK+
Sbjct: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387

Query: 421 RLELEIETYRRLLDGE-------AQGDGLEESLFVTDSKSQAQSTD---SSKDPTKTR-- 468
           RLE EI TYR LL+          +    E S + +      +ST    +S  P   +  
Sbjct: 388 RLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCSLKEH 447

Query: 469 ------------KIKTVVQEMVNGEVVSS 485
                       KI T+ +E+ +G+V+SS
Sbjct: 448 CSACGPLSRILVKICTITKEIKDGKVISS 476


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  281 bits (719), Expect = 1e-75
 Identities = 155/329 (47%), Positives = 217/329 (65%), Gaps = 4/329 (1%)

Query: 108 GSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTG 167
           G++GI        L+G EKETMQ LNDRLA+YL+KVR LE+ N ELE  + E    R   
Sbjct: 87  GNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLE----RSKC 142

Query: 168 TADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQG 227
                  DY  Y+  IE+L+ KI+ +   NA+L++QIDNA+LAA+DFR+K E+E +LRQ 
Sbjct: 143 HESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQL 202

Query: 228 VEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMD 287
           VEAD  G +++LD+ TL + DLE Q ESL EE   +K NHE E++  R     ++ +E+D
Sbjct: 203 VEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELD 262

Query: 288 AAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTD 347
             P +DL R+L +MRAQYE + E NR+D E WF  +S  +  +  + +E+LQ  +SE+ +
Sbjct: 263 IEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILE 322

Query: 348 LRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAER 407
           LR     LE+E Q+Q  +K  L++SL EAE  +  +L+Q+Q LISN+E QL ++RAD ER
Sbjct: 323 LRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLER 382

Query: 408 QNVDHQRLLNVKARLELEIETYRRLLDGE 436
           QN ++Q LL+VK RLE EI TYR LL+ E
Sbjct: 383 QNQEYQVLLDVKTRLENEIATYRNLLESE 411


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  281 bits (719), Expect = 1e-75
 Identities = 155/329 (47%), Positives = 215/329 (65%), Gaps = 4/329 (1%)

Query: 108 GSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTG 167
           G++GI        L+G EKETM+ LNDRLA+YL+KVR LE+ N ELE  + E    R   
Sbjct: 87  GNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLE----RSKC 142

Query: 168 TADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQG 227
                  DY  Y+  IE+L+ KI+ +   NA+L++QIDNA+LAA+DFR+K E+E +L Q 
Sbjct: 143 HESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQL 202

Query: 228 VEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMD 287
           VEAD  G +++LD+ TL + DLE Q ESL EE   +K NHE E++  R     +  +E+D
Sbjct: 203 VEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELD 262

Query: 288 AAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTD 347
             P +DL R+L +MRAQYE + E N +D E WF  +S  +  +  + +E+LQ  +SE+ +
Sbjct: 263 IEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILE 322

Query: 348 LRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAER 407
           LR     LE+E Q+Q  +K  L++SL EAE  Y  +L+Q+Q LISNLE QL ++RAD ER
Sbjct: 323 LRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLER 382

Query: 408 QNVDHQRLLNVKARLELEIETYRRLLDGE 436
           QN ++Q LL+VKARLE EI TYR LL+ E
Sbjct: 383 QNQEYQVLLDVKARLENEIATYRNLLESE 411


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,468,789
Number of Sequences: 37866
Number of extensions: 794178
Number of successful extensions: 16490
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 368
Number of HSP's successfully gapped in prelim test: 578
Number of HSP's that attempted gapping in prelim test: 5520
Number of HSP's gapped (non-prelim): 4776
length of query: 494
length of database: 18,247,518
effective HSP length: 106
effective length of query: 388
effective length of database: 14,233,722
effective search space: 5522684136
effective search space used: 5522684136
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.