Search of human proteins with 4505229

Search of human proteins with 4505229

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505229 Fas-associated via death domain [Homo sapiens]
         (208 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505229 Fas-associated via death domain [Homo sapiens]             408   e-114
gi|122056476 caspase 8 isoform G precursor [Homo sapiens]              49   2e-06
gi|122056474 caspase 8 isoform C precursor [Homo sapiens]              49   2e-06
gi|15718712 caspase 8 isoform E [Homo sapiens]                         49   2e-06
gi|15718708 caspase 8 isoform C precursor [Homo sapiens]               49   2e-06
gi|15718706 caspase 8 isoform B precursor [Homo sapiens]               49   2e-06
gi|15718704 caspase 8 isoform A precursor [Homo sapiens]               49   2e-06
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]                        49   2e-06
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]                         49   2e-06
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]                         49   2e-06
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]                         49   2e-06
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]                         48   5e-06
gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]          46   2e-05
gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]          46   2e-05
gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]          46   2e-05
gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinas...    46   3e-05
gi|187608585 CASP8 and FADD-like apoptosis regulator isoform 2 [...    39   0.003
gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1 [...    39   0.003
gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1 [...    39   0.003
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]                        39   0.004
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]                         39   0.004
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         39   0.004
gi|32967599 ankyrin 3 isoform 2 [Homo sapiens]                         37   0.009
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         37   0.009
gi|4503031 CASP2 and RIPK1 domain containing adaptor with death ...    34   0.077
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]            34   0.10 
gi|19923050 death effector domain-containing  DNA binding protei...    34   0.10 
gi|122937416 hypothetical protein LOC85452 [Homo sapiens]              32   0.29 
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...    31   0.65 
gi|33946313 ninein isoform 4 [Homo sapiens]                            31   0.65 

>gi|4505229 Fas-associated via death domain [Homo sapiens]
          Length = 208

 Score =  408 bits (1049), Expect = e-114
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MDPFLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHT 60
           MDPFLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHT
Sbjct: 1   MDPFLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHT 60

Query: 61  ELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLK 120
           ELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLK
Sbjct: 61  ELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLK 120

Query: 121 VSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEV 180
           VSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEV
Sbjct: 121 VSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEV 180

Query: 181 QQARDLQNRSGAMSPMSWNSDASTSEAS 208
           QQARDLQNRSGAMSPMSWNSDASTSEAS
Sbjct: 181 QQARDLQNRSGAMSPMSWNSDASTSEAS 208


>gi|122056476 caspase 8 isoform G precursor [Homo sapiens]
          Length = 538

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 27/69 (39%), Positives = 38/69 (55%)

Query: 8   LHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELL 67
           L+ +   L S +L  LKFL L  + +RK E ++  L LF  L E+  LE  +   L+ELL
Sbjct: 66  LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 125

Query: 68  ASLRRHDLL 76
             + R DLL
Sbjct: 126 FRINRLDLL 134



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 29/109 (26%), Positives = 56/109 (51%), Gaps = 10/109 (9%)

Query: 4   FLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELL 63
           + V+L+ +S  +S SEL   KFL    + K KL+   + LD+F  + ++  L  G  ++L
Sbjct: 160 YRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDIL 219

Query: 64  RELLASLRRHDLLRRVDDF-----EAGAAAGAAPGE----EDLCAAFNV 103
           + + A + +  LL+ ++D+     E  ++   +P E    E+LC    +
Sbjct: 220 KRVCAQINK-SLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTI 267


>gi|122056474 caspase 8 isoform C precursor [Homo sapiens]
          Length = 464

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 27/69 (39%), Positives = 38/69 (55%)

Query: 8  LHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELL 67
          L+ +   L S +L  LKFL L  + +RK E ++  L LF  L E+  LE  +   L+ELL
Sbjct: 7  LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66

Query: 68 ASLRRHDLL 76
            + R DLL
Sbjct: 67 FRINRLDLL 75



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 7/100 (7%)

Query: 4   FLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELL 63
           + V+L+ +S  +S SEL   KFL    + K KL+   + LD+F  + ++  L  G  ++L
Sbjct: 101 YRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDIL 160

Query: 64  RELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNV 103
           + + A + +  LL+ ++D+E  +        E+LC    +
Sbjct: 161 KRVCAQINK-SLLKIINDYEEFSKG------EELCGVMTI 193


>gi|15718712 caspase 8 isoform E [Homo sapiens]
          Length = 235

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 27/69 (39%), Positives = 38/69 (55%)

Query: 8  LHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELL 67
          L+ +   L S +L  LKFL L  + +RK E ++  L LF  L E+  LE  +   L+ELL
Sbjct: 7  LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66

Query: 68 ASLRRHDLL 76
            + R DLL
Sbjct: 67 FRINRLDLL 75



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 24/80 (30%), Positives = 46/80 (57%), Gaps = 1/80 (1%)

Query: 4   FLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELL 63
           + V+L+ +S  +S SEL   KFL    + K KL+   + LD+F  + ++  L  G  ++L
Sbjct: 101 YRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDIL 160

Query: 64  RELLASLRRHDLLRRVDDFE 83
           + + A + +  LL+ ++D+E
Sbjct: 161 KRVCAQINK-SLLKIINDYE 179


>gi|15718708 caspase 8 isoform C precursor [Homo sapiens]
          Length = 464

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 27/69 (39%), Positives = 38/69 (55%)

Query: 8  LHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELL 67
          L+ +   L S +L  LKFL L  + +RK E ++  L LF  L E+  LE  +   L+ELL
Sbjct: 7  LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66

Query: 68 ASLRRHDLL 76
            + R DLL
Sbjct: 67 FRINRLDLL 75



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 7/100 (7%)

Query: 4   FLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELL 63
           + V+L+ +S  +S SEL   KFL    + K KL+   + LD+F  + ++  L  G  ++L
Sbjct: 101 YRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDIL 160

Query: 64  RELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNV 103
           + + A + +  LL+ ++D+E  +        E+LC    +
Sbjct: 161 KRVCAQINK-SLLKIINDYEEFSKG------EELCGVMTI 193


>gi|15718706 caspase 8 isoform B precursor [Homo sapiens]
          Length = 479

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 27/69 (39%), Positives = 38/69 (55%)

Query: 8  LHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELL 67
          L+ +   L S +L  LKFL L  + +RK E ++  L LF  L E+  LE  +   L+ELL
Sbjct: 7  LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66

Query: 68 ASLRRHDLL 76
            + R DLL
Sbjct: 67 FRINRLDLL 75



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 29/109 (26%), Positives = 56/109 (51%), Gaps = 10/109 (9%)

Query: 4   FLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELL 63
           + V+L+ +S  +S SEL   KFL    + K KL+   + LD+F  + ++  L  G  ++L
Sbjct: 101 YRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDIL 160

Query: 64  RELLASLRRHDLLRRVDDF-----EAGAAAGAAPGE----EDLCAAFNV 103
           + + A + +  LL+ ++D+     E  ++   +P E    E+LC    +
Sbjct: 161 KRVCAQINK-SLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCGVMTI 208


>gi|15718704 caspase 8 isoform A precursor [Homo sapiens]
          Length = 496

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 27/69 (39%), Positives = 38/69 (55%)

Query: 8  LHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELL 67
          L+ +   L S +L  LKFL L  + +RK E ++  L LF  L E+  LE  +   L+ELL
Sbjct: 7  LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66

Query: 68 ASLRRHDLL 76
            + R DLL
Sbjct: 67 FRINRLDLL 75



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 7/98 (7%)

Query: 6   VLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRE 65
           V+L+ +S  +S SEL   KFL    + K KL+   + LD+F  + ++  L  G  ++L+ 
Sbjct: 135 VMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKR 194

Query: 66  LLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNV 103
           + A + +  LL+ ++D+E  +        E+LC    +
Sbjct: 195 VCAQINK-SLLKIINDYEEFSKG------EELCGVMTI 225


>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
          Length = 1897

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 7/125 (5%)

Query: 89   GAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIW 148
            G+  G E       VI +++G  W  LAR+L+ S   I+ I    P +L E+    L +W
Sbjct: 1436 GSLSGTEQAEMKMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLW 1495

Query: 149  KNTEKENATVAHLVGALRSCQMNLVADLVQ-EVQQARDLQ------NRSGAMSPMSWNSD 201
               E +NA + +L  AL+S     + ++++   +Q+R+L+      +R  ++SP   N  
Sbjct: 1496 VIREGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLKPDRRHTDRDYSLSPSQMNGY 1555

Query: 202  ASTSE 206
            +S  +
Sbjct: 1556 SSLQD 1560


>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
          Length = 1881

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 7/125 (5%)

Query: 89   GAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIW 148
            G+  G E       VI +++G  W  LAR+L+ S   I+ I    P +L E+    L +W
Sbjct: 1395 GSLSGTEQAEMKMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLW 1454

Query: 149  KNTEKENATVAHLVGALRSCQMNLVADLVQ-EVQQARDLQ------NRSGAMSPMSWNSD 201
               E +NA + +L  AL+S     + ++++   +Q+R+L+      +R  ++SP   N  
Sbjct: 1455 VIREGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLKPDRRHTDRDYSLSPSQMNGY 1514

Query: 202  ASTSE 206
            +S  +
Sbjct: 1515 SSLQD 1519


>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
          Length = 1880

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 7/125 (5%)

Query: 89   GAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIW 148
            G+  G E       VI +++G  W  LAR+L+ S   I+ I    P +L E+    L +W
Sbjct: 1395 GSLSGTEQAEMKMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLW 1454

Query: 149  KNTEKENATVAHLVGALRSCQMNLVADLVQ-EVQQARDLQ------NRSGAMSPMSWNSD 201
               E +NA + +L  AL+S     + ++++   +Q+R+L+      +R  ++SP   N  
Sbjct: 1455 VIREGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLKPDRRHTDRDYSLSPSQMNGY 1514

Query: 202  ASTSE 206
            +S  +
Sbjct: 1515 SSLQD 1519


>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
          Length = 1856

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 7/125 (5%)

Query: 89   GAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIW 148
            G+  G E       VI +++G  W  LAR+L+ S   I+ I    P +L E+    L +W
Sbjct: 1395 GSLSGTEQAEMKMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLW 1454

Query: 149  KNTEKENATVAHLVGALRSCQMNLVADLVQ-EVQQARDLQ------NRSGAMSPMSWNSD 201
               E +NA + +L  AL+S     + ++++   +Q+R+L+      +R  ++SP   N  
Sbjct: 1455 VIREGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLKPDRRHTDRDYSLSPSQMNGY 1514

Query: 202  ASTSE 206
            +S  +
Sbjct: 1515 SSLQD 1519


>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
          Length = 1719

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 7/118 (5%)

Query: 89   GAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIW 148
            G+  G E       VI +++G  W  LAR+L+ S   I+ I    P +L E+    L +W
Sbjct: 1395 GSLSGTEQAEMKMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLW 1454

Query: 149  KNTEKENATVAHLVGALRSCQMNLVADLVQ-EVQQARDLQ------NRSGAMSPMSWN 199
               E +NA + +L  AL+S     + ++++   +Q+R+L+      +R  ++SP   N
Sbjct: 1455 VIREGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLKPDRRHTDRDYSLSPSQMN 1512


>gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]
          Length = 522

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 25/70 (35%), Positives = 40/70 (57%)

Query: 11 VSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELLASL 70
          + S+L   ++  LKFLC+G V  +KLE+  S  D+F  LL ++ L       L ELL  +
Sbjct: 27 IDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLYII 86

Query: 71 RRHDLLRRVD 80
          R+  LL+ ++
Sbjct: 87 RQKKLLQHLN 96


>gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]
          Length = 521

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 25/70 (35%), Positives = 40/70 (57%)

Query: 11 VSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELLASL 70
          + S+L   ++  LKFLC+G V  +KLE+  S  D+F  LL ++ L       L ELL  +
Sbjct: 27 IDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLYII 86

Query: 71 RRHDLLRRVD 80
          R+  LL+ ++
Sbjct: 87 RQKKLLQHLN 96


>gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]
          Length = 479

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 25/70 (35%), Positives = 40/70 (57%)

Query: 11 VSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELLASL 70
          + S+L   ++  LKFLC+G V  +KLE+  S  D+F  LL ++ L       L ELL  +
Sbjct: 27 IDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAELLYII 86

Query: 71 RRHDLLRRVD 80
          R+  LL+ ++
Sbjct: 87 RQKKLLQHLN 96


>gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinase 1
           [Homo sapiens]
          Length = 671

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 28/77 (36%), Positives = 47/77 (61%), Gaps = 3/77 (3%)

Query: 104 ICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRN-LTERVRESLRIWKNTEK-ENATVAHL 161
           I +N+GK W+  AR+L  + ++ID I+  Y R+ L E+V + L+ W   E  + ATV  L
Sbjct: 590 IRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKL 649

Query: 162 VGALRSC-QMNLVADLV 177
             AL  C +++L++ L+
Sbjct: 650 AQALHQCSRIDLLSSLI 666


>gi|187608585 CASP8 and FADD-like apoptosis regulator isoform 2
           [Homo sapiens]
          Length = 221

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 47/188 (25%), Positives = 75/188 (39%), Gaps = 16/188 (8%)

Query: 7   LLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLREL 66
           ++H V  +L + E   L FLC           V+   DL  +L E+  L  G    L EL
Sbjct: 5   VIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVR---DLLDILRERGKLSVGD---LAEL 58

Query: 67  LASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTK- 125
           L  +RR DLL+R+   +  A          L + + V+   +G+D       L  SD   
Sbjct: 59  LYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGED-------LDKSDVSS 111

Query: 126 -IDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNL-VADLVQEVQQA 183
            I  ++D   R    + +  L +    EK N      +  L  C  N+   DL  ++Q+ 
Sbjct: 112 LIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKY 171

Query: 184 RDLQNRSG 191
           +     +G
Sbjct: 172 KQSVQGAG 179


>gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1
           [Homo sapiens]
          Length = 480

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 47/188 (25%), Positives = 75/188 (39%), Gaps = 16/188 (8%)

Query: 7   LLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLREL 66
           ++H V  +L + E   L FLC           V+   DL  +L E+  L  G    L EL
Sbjct: 5   VIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVR---DLLDILRERGKLSVGD---LAEL 58

Query: 67  LASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTK- 125
           L  +RR DLL+R+   +  A          L + + V+   +G+D       L  SD   
Sbjct: 59  LYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGED-------LDKSDVSS 111

Query: 126 -IDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNL-VADLVQEVQQA 183
            I  ++D   R    + +  L +    EK N      +  L  C  N+   DL  ++Q+ 
Sbjct: 112 LIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKY 171

Query: 184 RDLQNRSG 191
           +     +G
Sbjct: 172 KQSVQGAG 179


>gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1
           [Homo sapiens]
          Length = 480

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 47/188 (25%), Positives = 75/188 (39%), Gaps = 16/188 (8%)

Query: 7   LLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLREL 66
           ++H V  +L + E   L FLC           V+   DL  +L E+  L  G    L EL
Sbjct: 5   VIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVR---DLLDILRERGKLSVGD---LAEL 58

Query: 67  LASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTK- 125
           L  +RR DLL+R+   +  A          L + + V+   +G+D       L  SD   
Sbjct: 59  LYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGED-------LDKSDVSS 111

Query: 126 -IDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNL-VADLVQEVQQA 183
            I  ++D   R    + +  L +    EK N      +  L  C  N+   DL  ++Q+ 
Sbjct: 112 LIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKY 171

Query: 184 RDLQNRSG 191
           +     +G
Sbjct: 172 KQSVQGAG 179


>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
          Length = 1863

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 19/62 (30%), Positives = 33/62 (53%)

Query: 104  ICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVG 163
            I D++G  W  LAR+L  ++ +I  I    P +L ++    L+ W   + ++AT  +LV 
Sbjct: 1482 IADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVE 1541

Query: 164  AL 165
             L
Sbjct: 1542 CL 1543


>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 19/62 (30%), Positives = 33/62 (53%)

Query: 104  ICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVG 163
            I D++G  W  LAR+L  ++ +I  I    P +L ++    L+ W   + ++AT  +LV 
Sbjct: 1491 IADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVE 1550

Query: 164  AL 165
             L
Sbjct: 1551 CL 1552


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 19/62 (30%), Positives = 33/62 (53%)

Query: 104  ICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVG 163
            I D++G  W  LAR+L  ++ +I  I    P +L ++    L+ W   + ++AT  +LV 
Sbjct: 3576 IADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVE 3635

Query: 164  AL 165
             L
Sbjct: 3636 CL 3637


>gi|32967599 ankyrin 3 isoform 2 [Homo sapiens]
          Length = 1001

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 19/63 (30%), Positives = 31/63 (49%)

Query: 103 VICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLV 162
           ++ D++G  W  LAR+L  S  +I+ I    P +L  +    L+ W   + +NAT   L 
Sbjct: 617 IVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALT 676

Query: 163 GAL 165
             L
Sbjct: 677 SVL 679


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 19/63 (30%), Positives = 31/63 (49%)

Query: 103  VICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLV 162
            ++ D++G  W  LAR+L  S  +I+ I    P +L  +    L+ W   + +NAT   L 
Sbjct: 4096 IVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDALT 4155

Query: 163  GAL 165
              L
Sbjct: 4156 SVL 4158


>gi|4503031 CASP2 and RIPK1 domain containing adaptor with death
           domain [Homo sapiens]
          Length = 199

 Score = 34.3 bits (77), Expect = 0.077
 Identities = 17/70 (24%), Positives = 33/70 (47%)

Query: 102 NVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHL 161
           N +   +G +W  +   L +S T I   +  +P N+  +V E+   W+    + AT   L
Sbjct: 121 NQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSL 180

Query: 162 VGALRSCQMN 171
              LR+ +++
Sbjct: 181 HNGLRAVEVD 190


>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
          Length = 4523

 Score = 33.9 bits (76), Expect = 0.10
 Identities = 22/89 (24%), Positives = 46/89 (51%), Gaps = 3/89 (3%)

Query: 115  LARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVA 174
            L   LK + T ++S   + P  +  ++ E    W+ T+K  ATV H V  L + ++ L+ 
Sbjct: 1189 LFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIR 1248

Query: 175  D--LVQEVQQARDLQNRSGAMSPMSWNSD 201
               ++ + +QA + + R    +P+ +N++
Sbjct: 1249 KKCILFDAKQA-EFRERFRHYAPLGFNAE 1276


>gi|19923050 death effector domain-containing  DNA binding protein
          2 [Homo sapiens]
          Length = 326

 Score = 33.9 bits (76), Expect = 0.10
 Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 11 VSSSLSSSELTELKFLCLGRVGKRK-LERVQSGLDLFSMLLEQNDLEPGHTELLRELLAS 69
          V   L+  EL  L FL     G    L R +SGL+L   L  +   +  +  LL +LL  
Sbjct: 33 VGGQLTECELELLAFLLDEAPGAAGGLARARSGLELLLELERRGQCDESNLRLLGQLLRV 92

Query: 70 LRRHDLL 76
          L RHDLL
Sbjct: 93 LARHDLL 99


>gi|122937416 hypothetical protein LOC85452 [Homo sapiens]
          Length = 762

 Score = 32.3 bits (72), Expect = 0.29
 Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 22/158 (13%)

Query: 44  DLFSMLLE-QNDLEPGHTELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFN 102
           D+  +L E ++D++PGH+  ++EL                +  A        ED   AF+
Sbjct: 33  DIKCLLQEAEDDVDPGHSSSVKEL----------------DTDADKLKKKTAEDRTQAFH 76

Query: 103 VICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLV 162
           +  +    D     ++L     + +    R  R+L ++ +E++     TE+E   +A  V
Sbjct: 77  LRQNLSALDKMHEEQELFTEKMRGELRACRQRRDLIDKQQEAVAAEIATEEEAGNMA-AV 135

Query: 163 GALRSCQMNLVADLVQEVQQARDLQNRSGAMSPMSWNS 200
           G L++    L A+L  E    RDLQ+R+ A+   S N+
Sbjct: 136 GRLQAVSRRLFAELENE----RDLQSRTEAVLKESENT 169


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score = 31.2 bits (69), Expect = 0.65
 Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 4/73 (5%)

Query: 112 WRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIW-KNTEKENATVAHLVGALRSCQM 170
           W+   R+L +SD +ID +E +  R L E     L  W + T +  AT+  L   LR   M
Sbjct: 371 WKEFVRRLGLSDHEIDRLELQNGRCLREAQYSMLATWRRRTPRREATLELLGRVLR--DM 428

Query: 171 NLVADLVQEVQQA 183
           +L+  L +++++A
Sbjct: 429 DLLGCL-EDIEEA 440


>gi|33946313 ninein isoform 4 [Homo sapiens]
          Length = 2096

 Score = 31.2 bits (69), Expect = 0.65
 Identities = 43/175 (24%), Positives = 82/175 (46%), Gaps = 15/175 (8%)

Query: 5   LVLLHSVSSSLSSSELTELKFLCLGRVGK--RKLERVQSGLDLFSML--LEQNDLEPGHT 60
           LV  +S+  +  +S   E++ L L RV +  R+ E+++S LD    L  L  ++++  H 
Sbjct: 357 LVTKNSIHQAALASFKAEIRHL-LERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHA 415

Query: 61  ELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLK 120
            + R    +LR+ D     ++++   AA     + +L      I    GK    L ++++
Sbjct: 416 AIERRNEYNLRKLD-----EEYKERIAAL----KNELRKEREQILQQAGKQRLELEQEIE 466

Query: 121 VSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVAD 175
            + T+ + I DR   +L E  R    + +N EK  A   +L   L+    N++A+
Sbjct: 467 KAKTEENYIRDRLALSLKENSRLENELLENAEK-LAEYENLTNKLQRNLENVLAE 520


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,112,272
Number of Sequences: 37866
Number of extensions: 276014
Number of successful extensions: 880
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 834
Number of HSP's gapped (non-prelim): 62
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.