Search of human proteins with 4505061

Search of human proteins with 4505061

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505061 cation-dependent mannose-6-phosphate receptor
precursor [Homo sapiens]
         (277 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505061 cation-dependent mannose-6-phosphate receptor precurs...   570   e-163
gi|119964726 insulin-like growth factor 2 receptor precursor [Ho...    51   1e-06
gi|116008447 CAP-GLY domain containing linker protein 2 isoform ...    32   0.80 
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]         29   3.9  
gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2...    29   5.2  
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    29   5.2  
gi|209862859 DEP domain containing 5 isoform 3 [Homo sapiens]          28   8.8  
gi|7662222 DEP domain containing 5 isoform 1 [Homo sapiens]            28   8.8  
gi|27734865 unc-5 homolog C-like [Homo sapiens]                        28   8.8  

>gi|4505061 cation-dependent mannose-6-phosphate receptor precursor
           [Homo sapiens]
          Length = 277

 Score =  570 bits (1468), Expect = e-163
 Identities = 277/277 (100%), Positives = 277/277 (100%)

Query: 1   MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF 60
           MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF
Sbjct: 1   MFPFYSCWRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSF 60

Query: 61  ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML 120
           ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML
Sbjct: 61  ESTVGQGSDTYIYIFRVCREAGNHTSGAGLVQINKSNGKETVVGRLNETHIFNGSNWIML 120

Query: 121 IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 180
           IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS
Sbjct: 121 IYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACS 180

Query: 181 PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC 240
           PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC
Sbjct: 181 PEISHLSVGSILLVTFASLVAVYVVGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGC 240

Query: 241 DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM 277
           DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM
Sbjct: 241 DFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM 277


>gi|119964726 insulin-like growth factor 2 receptor precursor [Homo
           sapiens]
          Length = 2491

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 48/167 (28%), Positives = 70/167 (41%), Gaps = 17/167 (10%)

Query: 28  EEKTCDLVGEKGKESEKELALVKRLKPLFNKSFESTVGQGSDTYIYIFRVCREAGN---H 84
           E KTC L GE+   S         L PL      S +  G + Y++   VC E      +
Sbjct: 324 ESKTCSLSGEQQDVSID-------LTPLAQSGGSSYISDGKE-YLFYLNVCGETEIQFCN 375

Query: 85  TSGAGLVQINKSNGKET-VVGRLNETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMI 143
              A + Q+ KS+  +    GR +   +      + LIY GGDE  +     QR +V+  
Sbjct: 376 KKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDECSSGF---QRMSVINF 432

Query: 144 SCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGS 190
            CN+ T  ++        G+V DC Y F  D+  AC  E   L  G+
Sbjct: 433 ECNK-TAGNDGKGTPVFTGEV-DCTYFFTWDTEYACVKEKEDLLCGA 477



 Score = 35.4 bits (80), Expect = 0.055
 Identities = 43/166 (25%), Positives = 63/166 (37%), Gaps = 22/166 (13%)

Query: 25   WQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSFESTVGQGSDTYIYIFRVCREAGNH 84
            W+T E  C +V  +G   E +      L  L       T+    + Y Y FRVC +  + 
Sbjct: 1211 WRTVE-ACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGE-YTYYFRVCGKLSSD 1268

Query: 85   ---TSGAGLV-----QINKSNGKETVVGRLNETHIFNGSNWIMLIYKGGDEYDNHCGKE- 135
               TS    V     +  +  G   V G L +   +  +  + + + GGD     C K  
Sbjct: 1269 VCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYE-NGLLKMNFTGGDT----CHKVY 1323

Query: 136  QRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSP 181
            QR   +   C+R T    F        +  DC YLFE  +  AC P
Sbjct: 1324 QRSTAIFFYCDRGTQRPVFLK------ETSDCSYLFEWRTQYACPP 1363


>gi|116008447 CAP-GLY domain containing linker protein 2 isoform 1
           [Homo sapiens]
          Length = 1046

 Score = 31.6 bits (70), Expect = 0.80
 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 4/87 (4%)

Query: 109 THIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCF 168
           +HI      I L+    ++Y     ++ +RA +++   R    D  N + EER KV+D  
Sbjct: 387 SHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVESVRKEKVDLSNQLEEERRKVEDLQ 446

Query: 169 YLFEMDS----SLACSPEISHLSVGSI 191
           +  E +S     L    ++ H  +G +
Sbjct: 447 FRVEEESITKGDLETQTQLEHARIGEL 473


>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
          Length = 3639

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 19/57 (33%), Positives = 28/57 (49%)

Query: 9    RTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALVKRLKPLFNKSFESTVG 65
            R   L  L  V + E+W  E++    VG+ G++ E  L L +RL+     S   TVG
Sbjct: 2219 RRNFLEFLQRVDLAEAWIQEKEVKMNVGDLGQDLEHCLQLRRRLREFRGNSAGDTVG 2275


>gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2
           [Homo sapiens]
          Length = 1011

 Score = 28.9 bits (63), Expect = 5.2
 Identities = 18/67 (26%), Positives = 32/67 (47%)

Query: 109 THIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQDCF 168
           +HI      I L+    ++Y     ++ +RA +++   R    D  N + EER KV+D  
Sbjct: 387 SHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVESVRKEKVDLSNQLEEERRKVEDLQ 446

Query: 169 YLFEMDS 175
           +  E +S
Sbjct: 447 FRVEEES 453


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 28.9 bits (63), Expect = 5.2
 Identities = 12/29 (41%), Positives = 19/29 (65%)

Query: 244 CRSKPRNVPAAYRGVGDDQLGEESEERDD 272
           C+++PR V A+  G G D+  +E EE +D
Sbjct: 57  CKAEPRPVAASGGGPGGDEEEDEEEEEED 85


>gi|209862859 DEP domain containing 5 isoform 3 [Homo sapiens]
          Length = 1594

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 14/42 (33%), Positives = 20/42 (47%)

Query: 8   WRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALV 49
           WRT  LLL   V   +     E  CD+ G++ +  E E  L+
Sbjct: 933 WRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLL 974


>gi|7662222 DEP domain containing 5 isoform 1 [Homo sapiens]
          Length = 1572

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 14/42 (33%), Positives = 20/42 (47%)

Query: 8   WRTGLLLLLLAVAVRESWQTEEKTCDLVGEKGKESEKELALV 49
           WRT  LLL   V   +     E  CD+ G++ +  E E  L+
Sbjct: 933 WRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLL 974


>gi|27734865 unc-5 homolog C-like [Homo sapiens]
          Length = 518

 Score = 28.1 bits (61), Expect = 8.8
 Identities = 21/85 (24%), Positives = 35/85 (41%), Gaps = 9/85 (10%)

Query: 106 LNETHIFNGSNWIMLIYKGGDEYDNHCGKEQRRAVVMISCNRHTLADNFNPVSEERGKVQ 165
           L E +   G++W     +G   +   CG + R     +SC R   A       E+ G +Q
Sbjct: 419 LLEPNSITGNDW-----RGLASHLGLCGMKIR----FLSCQRSPAAAILELFEEQNGSLQ 469

Query: 166 DCFYLFEMDSSLACSPEISHLSVGS 190
           +  YL  +   L C+  I +   G+
Sbjct: 470 ELHYLMTVMERLDCASAIQNYLSGT 494


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,872,203
Number of Sequences: 37866
Number of extensions: 474133
Number of successful extensions: 904
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 891
Number of HSP's gapped (non-prelim): 15
length of query: 277
length of database: 18,247,518
effective HSP length: 101
effective length of query: 176
effective length of database: 14,423,052
effective search space: 2538457152
effective search space used: 2538457152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.