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Search of human proteins with 4504725
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504725 interferon regulatory factor 3 [Homo sapiens]
(427 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504725 interferon regulatory factor 3 [Homo sapiens] 902 0.0
gi|148833515 interferon regulatory factor 5 isoform c [Homo sapi... 175 6e-44
gi|148833492 interferon regulatory factor 5 isoform c [Homo sapi... 175 6e-44
gi|148833488 interferon regulatory factor 5 isoform c [Homo sapi... 175 6e-44
gi|148833496 interferon regulatory factor 5 isoform b [Homo sapi... 171 9e-43
gi|14249182 interferon regulatory factor 5 isoform b [Homo sapiens] 171 9e-43
gi|4504727 interferon regulatory factor 5 isoform a [Homo sapiens] 171 2e-42
gi|148833494 interferon regulatory factor 5 isoform d [Homo sapi... 169 3e-42
gi|5453700 interferon regulatory factor 6 [Homo sapiens] 160 2e-39
gi|4809284 interferon regulatory factor 7 isoform b [Homo sapiens] 154 1e-37
gi|98985819 interferon regulatory factor 7 isoform d [Homo sapiens] 153 3e-37
gi|4758610 interferon regulatory factor 7 isoform a [Homo sapiens] 153 3e-37
gi|167555104 interferon regulatory factor 4 [Homo sapiens] 138 1e-32
gi|4504567 interferon regulatory factor 8 [Homo sapiens] 129 7e-30
gi|25282407 interferon-stimulated transcription factor 3, gamma ... 102 9e-22
gi|153082752 interferon regulatory factor 2 [Homo sapiens] 83 5e-16
gi|4504721 interferon regulatory factor 1 [Homo sapiens] 81 2e-15
gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens] 41 0.002
gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens] 41 0.002
gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo ... 41 0.002
gi|4505405 glycoprotein (transmembrane) nmb isoform b precursor ... 39 0.009
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 37 0.034
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 37 0.034
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 37 0.034
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 36 0.076
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 35 0.100
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 35 0.100
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 35 0.100
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 35 0.100
gi|4503893 beta-1,4-N-acetyl-galactosaminyl transferase 1 [Homo ... 35 0.13
>gi|4504725 interferon regulatory factor 3 [Homo sapiens]
Length = 427
Score = 902 bits (2331), Expect = 0.0
Identities = 427/427 (100%), Positives = 427/427 (100%)
Query: 1 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA 60
MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA
Sbjct: 1 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEA 60
Query: 61 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP 120
TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP
Sbjct: 61 TGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQP 120
Query: 121 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT 180
DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT
Sbjct: 121 DTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPT 180
Query: 181 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG 240
PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG
Sbjct: 181 PFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPG 240
Query: 241 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL 300
WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL
Sbjct: 241 WPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELL 300
Query: 301 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK 360
PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK
Sbjct: 301 PNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTK 360
Query: 361 RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD 420
RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD
Sbjct: 361 RLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMD 420
Query: 421 FQGPGES 427
FQGPGES
Sbjct: 421 FQGPGES 427
>gi|148833515 interferon regulatory factor 5 isoform c [Homo
sapiens]
Length = 488
Score = 175 bits (444), Expect = 6e-44
Identities = 143/446 (32%), Positives = 205/446 (45%), Gaps = 55/446 (12%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAEATGAYV 65
R+ PWLV+Q++ Q G+ WVN + F IPW+H R Q+ D IF+AWA+ TG Y
Sbjct: 16 RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD-PHDPHKIYEFVNSGVGDF-SQPDTS 123
G D+ D WK N R ALN+ RL D +D P P+KIYE ++G SQP
Sbjct: 76 EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQP--P 133
Query: 124 PDTNGGGSTSDTQEDILDELLGNMVLA---------PLPDPGPPSLAVAPEPCPQPLRSP 174
D + G + +E+ L +L ++ L P PP + P P P PL +P
Sbjct: 134 EDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLQPPVVLGPPAPDPSPL-AP 192
Query: 175 SLDNPTPFPNLGP---SENPLKRLLVPGEE---------------WEFEVTAFYRGRQVF 216
NP F L PL L P E + E+ YRGR
Sbjct: 193 PPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPR 252
Query: 217 QQTISCPEGLRLVGSEV---GDRTLPGWPVTL-----PDPGMSLTDRGVMSYVRHVLSCL 268
TIS P G RL S++ ++ P++L P P +D+ Y +L L
Sbjct: 253 ALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDK-QRFYTNQLLDVL 311
Query: 269 GGGLALWRAGQWLWAQRLGHCHTYW----AVSEELLPNSGHGPDGEVPKDKEGGVFDLGP 324
GL L GQ L+A RL C +W A + + PN + ++ + +F L
Sbjct: 312 DRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPN-------PIQREVKTKLFSLEH 364
Query: 325 FIVDLITFTEG-SGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGG 383
F+ +LI F +G + P + ++FC GE WP +P K+L+ V+VVP R L+EM G
Sbjct: 365 FLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFS-GE 423
Query: 384 ASSLENTVDLHISNSHPLSLTSDQYK 409
S +++ L ISN +Q+K
Sbjct: 424 LSWSADSIRLQISNPDLKDRMVEQFK 449
>gi|148833492 interferon regulatory factor 5 isoform c [Homo
sapiens]
Length = 488
Score = 175 bits (444), Expect = 6e-44
Identities = 143/446 (32%), Positives = 205/446 (45%), Gaps = 55/446 (12%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAEATGAYV 65
R+ PWLV+Q++ Q G+ WVN + F IPW+H R Q+ D IF+AWA+ TG Y
Sbjct: 16 RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD-PHDPHKIYEFVNSGVGDF-SQPDTS 123
G D+ D WK N R ALN+ RL D +D P P+KIYE ++G SQP
Sbjct: 76 EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQP--P 133
Query: 124 PDTNGGGSTSDTQEDILDELLGNMVLA---------PLPDPGPPSLAVAPEPCPQPLRSP 174
D + G + +E+ L +L ++ L P PP + P P P PL +P
Sbjct: 134 EDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLQPPVVLGPPAPDPSPL-AP 192
Query: 175 SLDNPTPFPNLGP---SENPLKRLLVPGEE---------------WEFEVTAFYRGRQVF 216
NP F L PL L P E + E+ YRGR
Sbjct: 193 PPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPR 252
Query: 217 QQTISCPEGLRLVGSEV---GDRTLPGWPVTL-----PDPGMSLTDRGVMSYVRHVLSCL 268
TIS P G RL S++ ++ P++L P P +D+ Y +L L
Sbjct: 253 ALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDK-QRFYTNQLLDVL 311
Query: 269 GGGLALWRAGQWLWAQRLGHCHTYW----AVSEELLPNSGHGPDGEVPKDKEGGVFDLGP 324
GL L GQ L+A RL C +W A + + PN + ++ + +F L
Sbjct: 312 DRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPN-------PIQREVKTKLFSLEH 364
Query: 325 FIVDLITFTEG-SGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGG 383
F+ +LI F +G + P + ++FC GE WP +P K+L+ V+VVP R L+EM G
Sbjct: 365 FLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFS-GE 423
Query: 384 ASSLENTVDLHISNSHPLSLTSDQYK 409
S +++ L ISN +Q+K
Sbjct: 424 LSWSADSIRLQISNPDLKDRMVEQFK 449
>gi|148833488 interferon regulatory factor 5 isoform c [Homo
sapiens]
Length = 488
Score = 175 bits (444), Expect = 6e-44
Identities = 143/446 (32%), Positives = 205/446 (45%), Gaps = 55/446 (12%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAEATGAYV 65
R+ PWLV+Q++ Q G+ WVN + F IPW+H R Q+ D IF+AWA+ TG Y
Sbjct: 16 RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD-PHDPHKIYEFVNSGVGDF-SQPDTS 123
G D+ D WK N R ALN+ RL D +D P P+KIYE ++G SQP
Sbjct: 76 EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQP--P 133
Query: 124 PDTNGGGSTSDTQEDILDELLGNMVLA---------PLPDPGPPSLAVAPEPCPQPLRSP 174
D + G + +E+ L +L ++ L P PP + P P P PL +P
Sbjct: 134 EDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLQPPVVLGPPAPDPSPL-AP 192
Query: 175 SLDNPTPFPNLGP---SENPLKRLLVPGEE---------------WEFEVTAFYRGRQVF 216
NP F L PL L P E + E+ YRGR
Sbjct: 193 PPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPR 252
Query: 217 QQTISCPEGLRLVGSEV---GDRTLPGWPVTL-----PDPGMSLTDRGVMSYVRHVLSCL 268
TIS P G RL S++ ++ P++L P P +D+ Y +L L
Sbjct: 253 ALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDK-QRFYTNQLLDVL 311
Query: 269 GGGLALWRAGQWLWAQRLGHCHTYW----AVSEELLPNSGHGPDGEVPKDKEGGVFDLGP 324
GL L GQ L+A RL C +W A + + PN + ++ + +F L
Sbjct: 312 DRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPN-------PIQREVKTKLFSLEH 364
Query: 325 FIVDLITFTEG-SGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGG 383
F+ +LI F +G + P + ++FC GE WP +P K+L+ V+VVP R L+EM G
Sbjct: 365 FLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFS-GE 423
Query: 384 ASSLENTVDLHISNSHPLSLTSDQYK 409
S +++ L ISN +Q+K
Sbjct: 424 LSWSADSIRLQISNPDLKDRMVEQFK 449
>gi|148833496 interferon regulatory factor 5 isoform b [Homo
sapiens]
Length = 498
Score = 171 bits (434), Expect = 9e-43
Identities = 143/456 (31%), Positives = 205/456 (44%), Gaps = 65/456 (14%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAEATGAYV 65
R+ PWLV+Q++ Q G+ WVN + F IPW+H R Q+ D IF+AWA+ TG Y
Sbjct: 16 RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD-PHDPHKIYEFVNSGVGDF-SQPDTS 123
G D+ D WK N R ALN+ RL D +D P P+KIYE ++G SQP
Sbjct: 76 EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQP--P 133
Query: 124 PDTNGGGSTSDTQEDILDELLGNMVLA-------------------PLPDPGPPSLAVAP 164
D + G + +E+ L +L ++ L P PP + P
Sbjct: 134 EDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQPPTLQPPVVLGPP 193
Query: 165 EPCPQPLRSPSLDNPTPFPNLGP---SENPLKRLLVPGEE---------------WEFEV 206
P P PL +P NP F L PL L P E + E+
Sbjct: 194 APDPSPL-APPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLPLTDLEI 252
Query: 207 TAFYRGRQVFQQTISCPEGLRLVGSEV---GDRTLPGWPVTL-----PDPGMSLTDRGVM 258
YRGR TIS P G RL S++ ++ P++L P P +D+
Sbjct: 253 KFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDK-QR 311
Query: 259 SYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYW----AVSEELLPNSGHGPDGEVPKD 314
Y +L L GL L GQ L+A RL C +W A + + PN + ++
Sbjct: 312 FYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPN-------PIQRE 364
Query: 315 KEGGVFDLGPFIVDLITFTEG-SGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLR 373
+ +F L F+ +LI F +G + P + ++FC GE WP +P K+L+ V+VVP R
Sbjct: 365 VKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAAR 424
Query: 374 ALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYK 409
L+EM G S +++ L ISN +Q+K
Sbjct: 425 LLLEMFS-GELSWSADSIRLQISNPDLKDRMVEQFK 459
>gi|14249182 interferon regulatory factor 5 isoform b [Homo sapiens]
Length = 498
Score = 171 bits (434), Expect = 9e-43
Identities = 143/456 (31%), Positives = 205/456 (44%), Gaps = 65/456 (14%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAEATGAYV 65
R+ PWLV+Q++ Q G+ WVN + F IPW+H R Q+ D IF+AWA+ TG Y
Sbjct: 16 RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD-PHDPHKIYEFVNSGVGDF-SQPDTS 123
G D+ D WK N R ALN+ RL D +D P P+KIYE ++G SQP
Sbjct: 76 EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQP--P 133
Query: 124 PDTNGGGSTSDTQEDILDELLGNMVLA-------------------PLPDPGPPSLAVAP 164
D + G + +E+ L +L ++ L P PP + P
Sbjct: 134 EDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQPPTLQPPVVLGPP 193
Query: 165 EPCPQPLRSPSLDNPTPFPNLGP---SENPLKRLLVPGEE---------------WEFEV 206
P P PL +P NP F L PL L P E + E+
Sbjct: 194 APDPSPL-APPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLPLTDLEI 252
Query: 207 TAFYRGRQVFQQTISCPEGLRLVGSEV---GDRTLPGWPVTL-----PDPGMSLTDRGVM 258
YRGR TIS P G RL S++ ++ P++L P P +D+
Sbjct: 253 KFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDK-QR 311
Query: 259 SYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYW----AVSEELLPNSGHGPDGEVPKD 314
Y +L L GL L GQ L+A RL C +W A + + PN + ++
Sbjct: 312 FYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPN-------PIQRE 364
Query: 315 KEGGVFDLGPFIVDLITFTEG-SGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLR 373
+ +F L F+ +LI F +G + P + ++FC GE WP +P K+L+ V+VVP R
Sbjct: 365 VKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAAR 424
Query: 374 ALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYK 409
L+EM G S +++ L ISN +Q+K
Sbjct: 425 LLLEMFS-GELSWSADSIRLQISNPDLKDRMVEQFK 459
>gi|4504727 interferon regulatory factor 5 isoform a [Homo sapiens]
Length = 504
Score = 171 bits (432), Expect = 2e-42
Identities = 143/462 (30%), Positives = 204/462 (44%), Gaps = 71/462 (15%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAEATGAYV 65
R+ PWLV+Q++ Q G+ WVN + F IPW+H R Q+ D IF+AWA+ TG Y
Sbjct: 16 RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD-PHDPHKIYEFVNSGVGDF-SQPDTS 123
G D+ D WK N R ALN+ RL D +D P P+KIYE ++G SQP
Sbjct: 76 EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPE- 134
Query: 124 PDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGP-------------------------P 158
D + G + +E+ L +L ++ L GP P
Sbjct: 135 -DYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVKWPPTLQPPTLQPP 193
Query: 159 SLAVAPEPCPQPLRSPSLDNPTPFPNLGPS---ENPLKRLLVPGEEW------------- 202
+ P P P PL P NP F L PL L P E
Sbjct: 194 VVLGPPAPDPSPLAPPP-GNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLP 252
Query: 203 --EFEVTAFYRGRQVFQQTISCPEGLRLVGSEVG---DRTLPGWPVTL-----PDPGMSL 252
+ E+ YRGR TIS P G RL S++ ++ P++L P P
Sbjct: 253 LTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIP 312
Query: 253 TDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYW----AVSEELLPNSGHGPD 308
+D+ Y +L L GL L GQ L+A RL C +W A + + PN
Sbjct: 313 SDKQRF-YTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNP----- 366
Query: 309 GEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPR-YALWFCVGESWPQDQPWTKRLVMVKV 367
+ ++ + +F L F+ +LI F +G +P + ++FC GE WP +P K+L+ V+V
Sbjct: 367 --IQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQV 424
Query: 368 VPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYK 409
VP R L+EM G S +++ L ISN +Q+K
Sbjct: 425 VPVAARLLLEMFS-GELSWSADSIRLQISNPDLKDRMVEQFK 465
>gi|148833494 interferon regulatory factor 5 isoform d [Homo
sapiens]
Length = 514
Score = 169 bits (429), Expect = 3e-42
Identities = 144/471 (30%), Positives = 207/471 (43%), Gaps = 79/471 (16%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAEATGAYV 65
R+ PWLV+Q++ Q G+ WVN + F IPW+H R Q+ D IF+AWA+ TG Y
Sbjct: 16 RLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYT 75
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD-PHDPHKIYEFVNSGVGDF-SQPDTS 123
G D+ D WK N R ALN+ RL D +D P P+KIYE ++G SQP
Sbjct: 76 EGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQP--P 133
Query: 124 PDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGP---------PSLAVAPEPCPQPLRSP 174
D + G + +E+ L +L ++ L GP + P P LR P
Sbjct: 134 EDYSFGAGEEEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVKWPPTLQPPTLRPP 193
Query: 175 SLDNPT-------------PFPNLGPSENP------LKRLLVPG---------------- 199
+L PT P P P NP L +L PG
Sbjct: 194 TLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPD 253
Query: 200 --------EEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEV---GDRTLPGWPVTL--- 245
+ E+ YRGR TIS P G RL S++ ++ P++L
Sbjct: 254 LLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQV 313
Query: 246 --PDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYW----AVSEEL 299
P P +D+ Y +L L GL L GQ L+A RL C +W A + +
Sbjct: 314 RFPSPEDIPSDK-QRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDS 372
Query: 300 LPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEG-SGRSPRYALWFCVGESWPQDQPW 358
PN + ++ + +F L F+ +LI F +G + P + ++FC GE WP +P
Sbjct: 373 CPN-------PIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPR 425
Query: 359 TKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYK 409
K+L+ V+VVP R L+EM G S +++ L ISN +Q+K
Sbjct: 426 EKKLITVQVVPVAARLLLEMFS-GELSWSADSIRLQISNPDLKDRMVEQFK 475
>gi|5453700 interferon regulatory factor 6 [Homo sapiens]
Length = 467
Score = 160 bits (406), Expect = 2e-39
Identities = 125/409 (30%), Positives = 191/409 (46%), Gaps = 49/409 (11%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFG-IFQAWAEATGAYV 65
R+ PWLV+Q+D G G+ W+++ RF+IPWKH R QQE+ IF+AWA TG Y
Sbjct: 9 RLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRHSPQQEEENTIFKAWAVETGKYQ 68
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKD-PHDPHKIYEFVNSGVGDFSQPDTS- 123
G D PD WK R ALN+ L D +K+ P +P KIY+ V D QP S
Sbjct: 69 EGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMNPVKIYQ-----VCDIPQPQGSI 123
Query: 124 --PDTNGGGSTSD-----TQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPLRSPSL 176
P + G + +ED DEL + P+ D P P + + S+
Sbjct: 124 INPGSTGSAPWDEKDNDVDEEDEEDELDQSQHHVPIQDTFPFLNINGSPMAPASVGNCSV 183
Query: 177 DNPTP---FPNLGPSE-----NPLKRLLVPGEEW-------EFEVTAFYRGRQVFQ-QTI 220
N +P +P P E P++ E W + ++ YRG++ Q T+
Sbjct: 184 GNCSPEAVWPKTEPLEMEVPQAPIQPFYSSPELWISSLPMTDLDIKFQYRGKEYGQTMTV 243
Query: 221 SCPEGLRLVGSEVG---DRTLPGWPVTLPD---PGMS-LTDRGVMSYVRHVLSCLGGGLA 273
S P+G RL ++G D+ PV+L PG +T+ + +L + GL
Sbjct: 244 SNPQGCRLFYGDLGPMPDQEELFGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLI 303
Query: 274 LWRAGQWLWAQRLGHCHTYWA---VSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLI 330
L +G ++A RL C YW+ + PN + + K+ +F L F+ DLI
Sbjct: 304 LEVSGHAIYAIRLCQCKVYWSGPCAPSLVAPNL-------IERQKKVKLFCLETFLSDLI 356
Query: 331 TFTEGS-GRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEM 378
+G + P + ++ C GE WP +P ++L++V+V+P R + EM
Sbjct: 357 AHQKGQIEKQPPFEIYLCFGEEWPDGKPLERKLILVQVIPVVARMIYEM 405
>gi|4809284 interferon regulatory factor 7 isoform b [Homo sapiens]
Length = 474
Score = 154 bits (390), Expect = 1e-37
Identities = 131/466 (28%), Positives = 196/466 (42%), Gaps = 61/466 (13%)
Query: 6 PRIL--PWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGA 63
PR+L WL+ ++ G EG+ W++++RT FR+PWKH R+D + D IF+AWA A G
Sbjct: 10 PRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIFKAWAVARGR 69
Query: 64 YVP----GRDKPDLPT-----WKRNFRSALNRKEGLRLAEDRSKDPHDPHKIY------- 107
+ P G P+ T WK NFR AL + D S DP DPHK+Y
Sbjct: 70 WPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHKVYALSRELC 129
Query: 108 --EFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAPLPDPGPPSLAVAPE 165
E + + P P GG + AP D G L +
Sbjct: 130 WREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKGDLLLQAVQQ 189
Query: 166 PC-------------PQPLRSP-------------------SLDNP-TPFPNLGPSENPL 192
C P P ++P + ++P P L PS +
Sbjct: 190 SCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGEAAAPESPHQAEPYLSPSPSAC 249
Query: 193 KRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVG-SEVGDRTLPGWPVTLPDPGMS 251
+ P +VT Y+GR V Q+ + P L G + R V P P
Sbjct: 250 TAVQEP-SPGALDVTIMYKGRTVLQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPA-E 307
Query: 252 LTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEV 311
L D+ + Y +L + GL L G LWA+R+G C YW V S P +
Sbjct: 308 LPDQKQLRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLL 367
Query: 312 PKDKEGGVFDLGPFIVDLITFTEGSGR-SPRYALWFCVGESWPQDQPWTKRLVMVKVVPT 370
P++ + +FD F +L+ F R SPRY ++ G+ +P K LV+VK+ P
Sbjct: 368 PRNCDTPIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVLVKLEPW 427
Query: 371 CLRALVEMARVGGASSLE-NTVDLHISNSHPLSLTSDQYKAYLQDL 415
R +E + G SSL+ +++ L +S+++ L D + +L +L
Sbjct: 428 LCRVHLEGTQREGVSSLDSSSLSLCLSSANSL---YDDIECFLMEL 470
>gi|98985819 interferon regulatory factor 7 isoform d [Homo sapiens]
Length = 516
Score = 153 bits (386), Expect = 3e-37
Identities = 138/495 (27%), Positives = 203/495 (41%), Gaps = 90/495 (18%)
Query: 6 PRIL--PWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGA 63
PR+L WL+ ++ G EG+ W++++RT FR+PWKH R+D + D IF+AWA A G
Sbjct: 23 PRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIFKAWAVARGR 82
Query: 64 YVP----GRDKPDLPT-----WKRNFRSALNRKEGLRLAEDRSKDPHDPHKIY------- 107
+ P G P+ T WK NFR AL + D S DP DPHK+Y
Sbjct: 83 WPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHKVYALSRELC 142
Query: 108 --EFVNSGVGDFSQPDTSPDTNGG-----------------------GSTSD------TQ 136
E + + P P GG G D Q
Sbjct: 143 WREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKGDLLLQAVQQ 202
Query: 137 EDILDELL-GNMVLAPLP-------------------DPGPP-------SLAVAPEPCPQ 169
+ D LL + P+P PG P ++ P P PQ
Sbjct: 203 SCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAVETTPSPGPQ 262
Query: 170 PLRSPSLDNPTP------FPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCP 223
P + + P P L PS + + P +VT Y+GR V Q+ + P
Sbjct: 263 PAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEP-SPGALDVTIMYKGRTVLQKVVGHP 321
Query: 224 EGLRLVG-SEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLW 282
L G + R V P P L D+ + Y +L + GL L G LW
Sbjct: 322 SCTFLYGPPDPAVRATDPQQVAFPSPA-ELPDQKQLRYTEELLRHVAPGLHLELRGPQLW 380
Query: 283 AQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGR-SPR 341
A+R+G C YW V S P +P++ + +FD F +L+ F R SPR
Sbjct: 381 ARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRARQRRGSPR 440
Query: 342 YALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGASSLE-NTVDLHISNSHP 400
Y ++ G+ +P K LV+VK+ P R +E + G SSL+ +++ L +S+++
Sbjct: 441 YTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSLCLSSANS 500
Query: 401 LSLTSDQYKAYLQDL 415
L D + +L +L
Sbjct: 501 L---YDDIECFLMEL 512
>gi|4758610 interferon regulatory factor 7 isoform a [Homo sapiens]
Length = 503
Score = 153 bits (386), Expect = 3e-37
Identities = 138/495 (27%), Positives = 203/495 (41%), Gaps = 90/495 (18%)
Query: 6 PRIL--PWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGA 63
PR+L WL+ ++ G EG+ W++++RT FR+PWKH R+D + D IF+AWA A G
Sbjct: 10 PRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIFKAWAVARGR 69
Query: 64 YVP----GRDKPDLPT-----WKRNFRSALNRKEGLRLAEDRSKDPHDPHKIY------- 107
+ P G P+ T WK NFR AL + D S DP DPHK+Y
Sbjct: 70 WPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHKVYALSRELC 129
Query: 108 --EFVNSGVGDFSQPDTSPDTNGG-----------------------GSTSD------TQ 136
E + + P P GG G D Q
Sbjct: 130 WREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLPAPAGDKGDLLLQAVQQ 189
Query: 137 EDILDELL-GNMVLAPLP-------------------DPGPP-------SLAVAPEPCPQ 169
+ D LL + P+P PG P ++ P P PQ
Sbjct: 190 SCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAVETTPSPGPQ 249
Query: 170 PLRSPSLDNPTP------FPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCP 223
P + + P P L PS + + P +VT Y+GR V Q+ + P
Sbjct: 250 PAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEP-SPGALDVTIMYKGRTVLQKVVGHP 308
Query: 224 EGLRLVG-SEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLW 282
L G + R V P P L D+ + Y +L + GL L G LW
Sbjct: 309 SCTFLYGPPDPAVRATDPQQVAFPSPA-ELPDQKQLRYTEELLRHVAPGLHLELRGPQLW 367
Query: 283 AQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGR-SPR 341
A+R+G C YW V S P +P++ + +FD F +L+ F R SPR
Sbjct: 368 ARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRARQRRGSPR 427
Query: 342 YALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGASSLE-NTVDLHISNSHP 400
Y ++ G+ +P K LV+VK+ P R +E + G SSL+ +++ L +S+++
Sbjct: 428 YTIYLGFGQDLSAGRPKEKSLVLVKLEPWLCRVHLEGTQREGVSSLDSSSLSLCLSSANS 487
Query: 401 LSLTSDQYKAYLQDL 415
L D + +L +L
Sbjct: 488 L---YDDIECFLMEL 499
>gi|167555104 interferon regulatory factor 4 [Homo sapiens]
Length = 451
Score = 138 bits (347), Expect = 1e-32
Identities = 121/427 (28%), Positives = 179/427 (41%), Gaps = 49/427 (11%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQD-AQQEDFGIFQAWAEATGAYV 65
++ WL+ Q+D G+ G+ W N+ ++ FRIPWKH +QD ++ED +F+AWA G +
Sbjct: 23 KLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALFKAWALFKGKFR 82
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSK-DPHDPHKIYEFVNSGVGDFSQPDTSP 124
G DKPD PTWK R ALN+ +RS+ D DP+K+Y V G ++ T
Sbjct: 83 EGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDPYKVYRIVPEGAKKGAKQLTLE 142
Query: 125 DTNGGGSTSDTQEDILDEL----LGNMVLAPL--------PDPGPPSLAVAPEPCPQPL- 171
D S T L + N ++ PL PD P + P CP
Sbjct: 143 DPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRSWRDYVPDQPHPEI---PYQCPMTFG 199
Query: 172 ------RSPSLDN----PTPFPNLGPSEN-----PLKRLLVPGEEWEF-----EVTAFYR 211
+ P+ +N F P E+ P + + E F + +YR
Sbjct: 200 PRGHHWQGPACENGCQVTGTFYACAPPESQAPGVPTEPSIRSAEALAFSDCRLHICLYYR 259
Query: 212 GRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGG 271
V + T S PEG R+ D + V P P D G + +LS L G
Sbjct: 260 EILVKELTTSSPEGCRISHGHTYDASNLD-QVLFPYP----EDNGQRKNIEKLLSHLERG 314
Query: 272 LALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLIT 331
+ LW A L+A+RL YW L + ++ +D+ +FD F+ +L
Sbjct: 315 VVLWMAPDGLYAKRLCQSRIYWDGPLALC----NDRPNKLERDQTCKLFDTQQFLSELQA 370
Query: 332 FTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGASSLEN-T 390
F PR+ + C GE +P Q ++L+ V P R L A+ L
Sbjct: 371 FAHHGRSLPRFQVTLCFGEEFPDPQR-QRKLITAHVEPLLARQLYYFAQQNSGHFLRGYD 429
Query: 391 VDLHISN 397
+ HISN
Sbjct: 430 LPEHISN 436
>gi|4504567 interferon regulatory factor 8 [Homo sapiens]
Length = 426
Score = 129 bits (323), Expect = 7e-30
Identities = 109/400 (27%), Positives = 172/400 (43%), Gaps = 54/400 (13%)
Query: 7 RILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAEATGAYV 65
R+ WL+ Q+D G+ W N+ ++ FRIPWKH +QD QE D IF+AWA G +
Sbjct: 9 RLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFK 68
Query: 66 PGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSK-DPHDPHKIYEFV-------NSGVGDF 117
G DK + TWK R ALN+ DRS+ D +P+K+Y V GV
Sbjct: 69 EG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGVATA 127
Query: 118 SQPDTSPDTNGGGSTSD--TQEDILDELLGNMVLAPLPDPGPPSLAVAPEPCPQPL---- 171
+ + G S D +E +D+ +G + +P P PE C L
Sbjct: 128 GCVNEVTEMECGRSEIDELIKEPSVDDYMGMIKRSPSP----------PEACRSQLLPDW 177
Query: 172 --RSPSLDNP--TPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLR 227
+ PS P T + + +++ ++ +Y G+ V Q T +CPEG R
Sbjct: 178 WAQQPSTGVPLVTGYTTYDAHHSAFSQMV---------ISFYYGGKLVGQATTTCPEGCR 228
Query: 228 LVGSEVGDRTLPGWPVTLPD--------PGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQ 279
L S+ G LPG + P+ P ++ R + L G+ L + Q
Sbjct: 229 LSLSQPG---LPGTKLYGPEGLELVRFPPADAIPSERQRQVTRKLFGHLERGVLLHSSRQ 285
Query: 280 WLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRS 339
++ +RL + + + + G ++ +D+ VFD F +L F GR
Sbjct: 286 GVFVKRLCQGRVFCSGNAVVC----KGRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRL 341
Query: 340 PRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMA 379
P + C GE +P P +L++V++ +R L E A
Sbjct: 342 PDGRVVLCFGEEFPDMAPLRSKLILVQIEQLYVRQLAEEA 381
>gi|25282407 interferon-stimulated transcription factor 3, gamma
48kDa [Homo sapiens]
Length = 393
Score = 102 bits (253), Expect = 9e-22
Identities = 103/394 (26%), Positives = 165/394 (41%), Gaps = 55/394 (13%)
Query: 11 WLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQD-AQQEDFGIFQAWAEATGAYVPGRD 69
W+V Q++ GQ GV W + ++T FRIPWKH +QD + +D F+AWA G Y G D
Sbjct: 15 WVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQDFREDQDAAFFKAWAIFKGKYKEG-D 73
Query: 70 KPDLPTWKRNFRSALNRKEGLRLAEDRSK-DPHDPHKIYEFVNSGVGDFSQPDTS--PDT 126
WK R ALN+ + +R + D +P+K+Y+ + G+ QP T P
Sbjct: 74 TGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAEPYKVYQLLPPGIVS-GQPGTQKVPSK 132
Query: 127 NGGGSTSDTQEDILDELLGNMVLAPL-------------------PDPGPPSLAVAPEPC 167
S S +++ ++ + N L+P D G S + +PEP
Sbjct: 133 RQHSSVSSERKE-EEDAMQNCTLSPSVLQDSLNNEEEGASGGAVHSDIGSSSSSSSPEP- 190
Query: 168 PQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQ---QTISCPE 224
+ + T P G + L+ LL P ++ +T Y GR V + Q++ C
Sbjct: 191 ------QEVTDTTEAPFQG-DQRSLEFLLPPEPDYSLLLTFIYNGRVVGEAQVQSLDC-- 241
Query: 225 GLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQ 284
RLV G + V P P G + + +LS L G+ + + L+ Q
Sbjct: 242 --RLVAEPSGSESSME-QVLFPKP-------GPLEPTQRLLSQLERGILVASNPRGLFVQ 291
Query: 285 RLGHCHTYWAVSEELLPNSGHGPDGE-VPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYA 343
RL W P + GP +P ++ +F F DL+ + +G G P++
Sbjct: 292 RLCPIPISWNA-----PQAPPGPGPHLLPSNECVELFRTAYFCRDLVRYFQGLGPPPKFQ 346
Query: 344 LWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVE 377
+ E + L+ VK+ R L+E
Sbjct: 347 VTLNFWEESHGSSHTPQNLITVKMEQAFARYLLE 380
>gi|153082752 interferon regulatory factor 2 [Homo sapiens]
Length = 349
Score = 82.8 bits (203), Expect = 5e-16
Identities = 41/112 (36%), Positives = 62/112 (55%), Gaps = 2/112 (1%)
Query: 1 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQE-DFGIFQAWAE 59
M + R+ PWL Q++ + G+ W+NK + F+IPW H R E D +F+ WA
Sbjct: 1 MPVERMRMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARHGWDVEKDAPLFRNWAI 60
Query: 60 ATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRS-KDPHDPHKIYEFV 110
TG + PG DKPD TWK NFR A+N + +D+S K ++ ++Y +
Sbjct: 61 HTGKHQPGVDKPDPKTWKANFRCAMNSLPDIEEVKDKSIKKGNNAFRVYRML 112
>gi|4504721 interferon regulatory factor 1 [Homo sapiens]
Length = 325
Score = 81.3 bits (199), Expect = 2e-15
Identities = 49/159 (30%), Positives = 74/159 (46%), Gaps = 21/159 (13%)
Query: 1 MGTPKPRILPWLVSQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQ-QEDFGIFQAWAE 59
M + R+ PWL Q++ Q+ G+ W+NK F+IPWKH + +D +F++WA
Sbjct: 1 MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAI 60
Query: 60 ATGAYVPGRDKPDLPTWKRNFRSALNRKEGLRLAEDRSKDP-HDPHKIYEFV-------- 110
TG Y G +PD TWK NFR A+N + +D+S++ ++Y +
Sbjct: 61 HTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTKNQR 120
Query: 111 -----------NSGVGDFSQPDTSPDTNGGGSTSDTQED 138
S S D+SPDT G +S T D
Sbjct: 121 KERKSKSSRDAKSKAKRKSCGDSSPDTFSDGLSSSTLPD 159
>gi|239757474 PREDICTED: similar to hCG1785205 [Homo sapiens]
Length = 362
Score = 40.8 bits (94), Expect = 0.002
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 8/61 (13%)
Query: 14 SQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDL 73
+Q++ G G+ W + +T FRIPWKH +Q +QAW G ++ G +K
Sbjct: 15 AQIESGCYVGLCWEDAGKTLFRIPWKHVAKQG--------YQAWMVHKGKHLEGTNKEAP 66
Query: 74 P 74
P
Sbjct: 67 P 67
>gi|239751984 PREDICTED: similar to hCG1785205 [Homo sapiens]
Length = 362
Score = 40.8 bits (94), Expect = 0.002
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 8/61 (13%)
Query: 14 SQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDL 73
+Q++ G G+ W + +T FRIPWKH +Q +QAW G ++ G +K
Sbjct: 15 AQIESGCYVGLCWEDAGKTLFRIPWKHVAKQG--------YQAWMVHKGKHLEGTNKEAP 66
Query: 74 P 74
P
Sbjct: 67 P 67
>gi|239746471 PREDICTED: hypothetical protein XP_002343764 [Homo
sapiens]
Length = 362
Score = 40.8 bits (94), Expect = 0.002
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 8/61 (13%)
Query: 14 SQLDLGQLEGVAWVNKSRTRFRIPWKHGLRQDAQQEDFGIFQAWAEATGAYVPGRDKPDL 73
+Q++ G G+ W + +T FRIPWKH +Q +QAW G ++ G +K
Sbjct: 15 AQIESGCYVGLCWEDAGKTLFRIPWKHVAKQG--------YQAWMVHKGKHLEGTNKEAP 66
Query: 74 P 74
P
Sbjct: 67 P 67
>gi|4505405 glycoprotein (transmembrane) nmb isoform b precursor
[Homo sapiens]
Length = 560
Score = 38.9 bits (89), Expect = 0.009
Identities = 33/96 (34%), Positives = 45/96 (46%), Gaps = 15/96 (15%)
Query: 161 AVAPEPCPQPLRSPSLDNPTPFPNLGPS-ENPLKRLLVPGEEWEFEVTAFYRGRQVFQQT 219
A AP PCP P P PT P+LGP+ +NPL+ +P E + FQ T
Sbjct: 317 AAAPGPCPPPPPPPRPSKPT--PSLGPAGDNPLELSRIPDENCQINRYGH------FQAT 368
Query: 220 ISCPEGLRLVG-SEVGDRTLPGWPVTLPDPGMSLTD 254
I+ EG+ V ++ D +P +P P SL D
Sbjct: 369 ITIVEGILEVNIIQMTDVLMP-----VPWPESSLID 399
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 37.0 bits (84), Expect = 0.034
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 148 VLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPF--PNLGPSENPL 192
+L +P P P S A +P PCP PL + + +P P P + PS +P+
Sbjct: 788 LLPTVPLPAPSSSA-SPHPCPSPLSNATAQSPLPILSPTVSPSPSPI 833
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 37.0 bits (84), Expect = 0.034
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 148 VLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPF--PNLGPSENPL 192
+L +P P P S A +P PCP PL + + +P P P + PS +P+
Sbjct: 989 LLPTVPLPAPSSSA-SPHPCPSPLSNATAQSPLPILSPTVSPSPSPI 1034
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 37.0 bits (84), Expect = 0.034
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 148 VLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPF--PNLGPSENPL 192
+L +P P P S A +P PCP PL + + +P P P + PS +P+
Sbjct: 989 LLPTVPLPAPSSSA-SPHPCPSPLSNATAQSPLPILSPTVSPSPSPI 1034
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 35.8 bits (81), Expect = 0.076
Identities = 27/100 (27%), Positives = 36/100 (36%), Gaps = 16/100 (16%)
Query: 92 LAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGNMVLAP 151
LAE ++K+ + N G GD P + GG+ ++D LL
Sbjct: 266 LAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRR----- 320
Query: 152 LPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENP 191
+L P PCP PL P P P GP P
Sbjct: 321 -----TETLLPGPRPCPSPL------PPPPAPPKGPPAPP 349
Score = 30.8 bits (68), Expect = 2.5
Identities = 19/50 (38%), Positives = 22/50 (44%), Gaps = 3/50 (6%)
Query: 151 PLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGE 200
PLP GP LA++PE P L + P GP E PL V E
Sbjct: 1115 PLPADGPERLALSPEDKPIRLSPSKITEPL---REGPEEEPLAEREVKAE 1161
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 35.4 bits (80), Expect = 0.100
Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 9/106 (8%)
Query: 86 RKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLG 145
R+E R ++R+K+ + E G G P T P G SD +L+
Sbjct: 517 REEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDP--LAGLVLSDNDRSLLERW-- 572
Query: 146 NMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENP 191
+ P P+L P P P P +P+ PT P GP P
Sbjct: 573 ----TRMARPAAPALTSVPAPAPAPTPTPTPVQPTS-PPPGPVAQP 613
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 35.4 bits (80), Expect = 0.100
Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 9/106 (8%)
Query: 86 RKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLG 145
R+E R ++R+K+ + E G G P T P G SD +L+
Sbjct: 517 REEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDP--LAGLVLSDNDRSLLERW-- 572
Query: 146 NMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENP 191
+ P P+L P P P P +P+ PT P GP P
Sbjct: 573 ----TRMARPAAPALTSVPAPAPAPTPTPTPVQPTS-PPPGPVAQP 613
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 35.4 bits (80), Expect = 0.100
Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 9/106 (8%)
Query: 86 RKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLG 145
R+E R ++R+K+ + E G G P T P G SD +L+
Sbjct: 517 REEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDP--LAGLVLSDNDRSLLERW-- 572
Query: 146 NMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENP 191
+ P P+L P P P P +P+ PT P GP P
Sbjct: 573 ----TRMARPAAPALTSVPAPAPAPTPTPTPVQPTS-PPPGPVAQP 613
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 35.4 bits (80), Expect = 0.100
Identities = 29/106 (27%), Positives = 41/106 (38%), Gaps = 9/106 (8%)
Query: 86 RKEGLRLAEDRSKDPHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLG 145
R+E R ++R+K+ + E G G P T P G SD +L+
Sbjct: 378 REEKRRRRQERAKEREKRRQERERKERGAGASGGPSTDP--LAGLVLSDNDRSLLERW-- 433
Query: 146 NMVLAPLPDPGPPSLAVAPEPCPQPLRSPSLDNPTPFPNLGPSENP 191
+ P P+L P P P P +P+ PT P GP P
Sbjct: 434 ----TRMARPAAPALTSVPAPAPAPTPTPTPVQPTS-PPPGPVAQP 474
>gi|4503893 beta-1,4-N-acetyl-galactosaminyl transferase 1 [Homo
sapiens]
Length = 533
Score = 35.0 bits (79), Expect = 0.13
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 9/99 (9%)
Query: 160 LAVAPEPCPQPLRSPSLDNPTPFPNLGPSENPLKRLLVPGEEWEFEVTAFYRGRQVFQQT 219
L+ + P Q L +P+ ++P +P G PL+ +LVPG + G++V+Q
Sbjct: 126 LSRSQSPADQLLIAPA-NSPLQYPLQGVEVQPLRSILVPGLSLQAA-----SGQEVYQVN 179
Query: 220 ISCPEGLRLVGSEVGDRTLPG---WPVTLPDPGMSLTDR 255
++ G V EV TL G +TL PG+ +R
Sbjct: 180 LTASLGTWDVAGEVTGVTLTGEGQADLTLVSPGLDQLNR 218
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.138 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,889,502
Number of Sequences: 37866
Number of extensions: 1214707
Number of successful extensions: 6592
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 148
Number of HSP's that attempted gapping in prelim test: 5836
Number of HSP's gapped (non-prelim): 760
length of query: 427
length of database: 18,247,518
effective HSP length: 105
effective length of query: 322
effective length of database: 14,271,588
effective search space: 4595451336
effective search space used: 4595451336
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.