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Search of human proteins with 4504489
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
(525 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 1174 0.0
gi|58331240 fetuin B [Homo sapiens] 79 8e-15
gi|197304786 IQ motif and Sec7 domain 1 isoform a [Homo sapiens] 76 7e-14
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 61 2e-09
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 61 2e-09
gi|59938776 cAMP responsive element binding protein 5 isoform de... 60 6e-09
gi|59938774 cAMP responsive element binding protein 5 isoform be... 60 6e-09
gi|59938772 cAMP responsive element binding protein 5 isoform ga... 60 6e-09
gi|59938770 cAMP responsive element binding protein 5 isoform al... 60 6e-09
gi|221316609 sperm-associated cation channel 1 [Homo sapiens] 59 1e-08
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 57 3e-08
gi|61966923 forkhead box B2 [Homo sapiens] 57 5e-08
gi|32698730 nuclear fragile X mental retardation protein interac... 56 7e-08
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 55 1e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 55 2e-07
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 54 3e-07
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 53 6e-07
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 53 6e-07
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens] 52 2e-06
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 52 2e-06
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 52 2e-06
gi|83977459 pleckstrin homology-like domain, family A, member 1 ... 52 2e-06
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 51 2e-06
gi|224548950 hypothetical protein LOC644844 [Homo sapiens] 51 2e-06
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 50 5e-06
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 50 5e-06
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 50 5e-06
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 50 5e-06
gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo... 50 5e-06
gi|9955927 acrosomal vesicle protein 1 isoform b precursor [Homo... 50 5e-06
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 1174 bits (3036), Expect = 0.0
Identities = 525/525 (100%), Positives = 525/525 (100%)
Query: 1 MKALIAALLLITLQYSCAVSPTDCSAVEPEAEKALDLINKRRRDGYLFQLLRIADAHLDR 60
MKALIAALLLITLQYSCAVSPTDCSAVEPEAEKALDLINKRRRDGYLFQLLRIADAHLDR
Sbjct: 1 MKALIAALLLITLQYSCAVSPTDCSAVEPEAEKALDLINKRRRDGYLFQLLRIADAHLDR 60
Query: 61 VENTTVYYLVLDVQESDCSVLSRKYWNDCEPPDSRRPSEIVIGQCKVIATRHSHESQDLR 120
VENTTVYYLVLDVQESDCSVLSRKYWNDCEPPDSRRPSEIVIGQCKVIATRHSHESQDLR
Sbjct: 61 VENTTVYYLVLDVQESDCSVLSRKYWNDCEPPDSRRPSEIVIGQCKVIATRHSHESQDLR 120
Query: 121 VIDFNCTTSSVSSALANTKDSPVLIDFFEDTERYRKQANKALEKYKEENDDFASFRVDRI 180
VIDFNCTTSSVSSALANTKDSPVLIDFFEDTERYRKQANKALEKYKEENDDFASFRVDRI
Sbjct: 121 VIDFNCTTSSVSSALANTKDSPVLIDFFEDTERYRKQANKALEKYKEENDDFASFRVDRI 180
Query: 181 ERVARVRGGEGTGYFVDFSVRNCPRHHFPRHPNVFGFCRADLFYDVEALDLESPKNLVIN 240
ERVARVRGGEGTGYFVDFSVRNCPRHHFPRHPNVFGFCRADLFYDVEALDLESPKNLVIN
Sbjct: 181 ERVARVRGGEGTGYFVDFSVRNCPRHHFPRHPNVFGFCRADLFYDVEALDLESPKNLVIN 240
Query: 241 CEVFDPQEHENINGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPP 300
CEVFDPQEHENINGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPP
Sbjct: 241 CEVFDPQEHENINGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPP 300
Query: 301 PDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQH 360
PDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQH
Sbjct: 301 PDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQH 360
Query: 361 PHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPP 420
PHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPP
Sbjct: 361 PHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPP 420
Query: 421 PHNQGHCCHGHGPPPGHLRRRGPGKGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANFPSF 480
PHNQGHCCHGHGPPPGHLRRRGPGKGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANFPSF
Sbjct: 421 PHNQGHCCHGHGPPPGHLRRRGPGKGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANFPSF 480
Query: 481 PLPHHKHPLKPDNQPFPQSVSESCPGKFKSGFPQVSMFFTHTFPK 525
PLPHHKHPLKPDNQPFPQSVSESCPGKFKSGFPQVSMFFTHTFPK
Sbjct: 481 PLPHHKHPLKPDNQPFPQSVSESCPGKFKSGFPQVSMFFTHTFPK 525
>gi|58331240 fetuin B [Homo sapiens]
Length = 382
Score = 79.3 bits (194), Expect = 8e-15
Identities = 61/176 (34%), Positives = 87/176 (49%), Gaps = 13/176 (7%)
Query: 34 ALDLINKRRRDGYLFQLLRIADAHLDRVENT-TVYYLVLDVQESDCSVLSRKYWNDCEPP 92
AL INK R+DGY+ +L R+ DA R +++YL LDV E+DC VL +K W DC
Sbjct: 48 ALRDINKDRKDGYVLRLNRVNDAQEYRRGGLGSLFYLTLDVLETDCHVLRKKAWQDC--- 104
Query: 93 DSRRPSEIVIGQCKVIATRHSHESQDLRVIDFNCTTSSVS--SALANTKDSPVLIDFFED 150
R E V GQCK I ++ S+ L + +NCT VS D P I
Sbjct: 105 GMRIFFESVYGQCKAIFYM-NNPSRVLYLAAYNCTLRPVSKKKIYMTCPDCPSSIPTDSS 163
Query: 151 TERYRKQANKALEKYKEEN--DDFASFRVDRIERVARVRGGEGTGYFVDFSVRNCP 204
+ + A ++L KY EN ++ F+V R A + G YFV++ ++ P
Sbjct: 164 NHQVLEAATESLAKYNNENTSKQYSLFKVTR----ASSQWVVGPSYFVEYLIKESP 215
>gi|197304786 IQ motif and Sec7 domain 1 isoform a [Homo sapiens]
Length = 1114
Score = 76.3 bits (186), Expect = 7e-14
Identities = 56/185 (30%), Positives = 72/185 (38%), Gaps = 42/185 (22%)
Query: 269 ERSSTTKPPFKPHGSRDHHHPHKPHE----------------HGPPPPPDERDHSHGPPL 312
E S + P + + P +PH+ G PPP +H P
Sbjct: 935 EGSIISSPHMRRRATSTRECPSRPHQTMPNSSSLLGSLFGSKRGKPPP-----QAHLPSA 989
Query: 313 PQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHG-HHPHAHHP 371
P PPP P+ QH+ G + + H H + H Q+P HH H HHP
Sbjct: 990 PALPPPHPPVVLPHLQHSVAGHHLGPPEGLPQAAMHGH-HTQYCHMQNPPPYHHHHHHHP 1048
Query: 372 HEHDTHRQHPHGHHPHGHHPHGHHP-HGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHG 430
+H QH H +H H PHG HP +G H HGH P P + GH H
Sbjct: 1049 PQHI---QHAHQYH---HGPHGGHPAYGAHAHGHPPL------------PSAHVGHTVHH 1090
Query: 431 HGPPP 435
HG PP
Sbjct: 1091 HGQPP 1095
Score = 33.1 bits (74), Expect = 0.64
Identities = 21/76 (27%), Positives = 27/76 (35%), Gaps = 17/76 (22%)
Query: 246 PQEHENINGVPPHL--GHPFHWGGHERSSTTKPPFKPHGSRDHHHP--------HKPHEH 295
P H + + P H+ H +H G H +G+ H HP H H H
Sbjct: 1039 PYHHHHHHHPPQHIQHAHQYHHGPHGGHPA-------YGAHAHGHPPLPSAHVGHTVHHH 1091
Query: 296 GPPPPPDERDHSHGPP 311
G PP P S P
Sbjct: 1092 GQPPAPPPPTSSKAKP 1107
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/96 (37%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
Query: 336 GAQRHSHNNNSSDLHPHKH-HSHEQHPHGH-HPHAH--------HPHEHDTHRQHPHGHH 385
G H++ D H H H HSHE HGH H H H H H HD H H
Sbjct: 29 GGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDL 88
Query: 386 PHGH-HPHGHHPHGHHPHGHHPHCHDFQDYGPCDPP 420
HGH H + H H HG H H H YG P
Sbjct: 89 HHGHSHGYSHESLYHRGHG-HDHEHSHGGYGESGAP 123
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/84 (35%), Positives = 33/84 (39%), Gaps = 16/84 (19%)
Query: 370 HPHEHDTHRQHPHGHHPHGHHPHGHHPHGH-HPHGH--------HPHCHDFQDYGPCDPP 420
H HD ++ HGH H H HGH H HGH H H HD D+G
Sbjct: 31 HDDLHDDLQEDFHGHSHR--HSHEDFHHGHSHAHGHGHTHESIWHGHTHD-HDHG----H 83
Query: 421 PHNQGHCCHGHGPPPGHLRRRGPG 444
H H H HG L RG G
Sbjct: 84 SHEDLHHGHSHGYSHESLYHRGHG 107
Score = 38.9 bits (89), Expect = 0.012
Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 20/71 (28%)
Query: 349 LHPHKHHSHEQHPHGHHPHAHHP------------------HEHDTHRQHPHGH-HPHGH 389
L PH HH+ EQ HGH P + H + HGH H HGH
Sbjct: 193 LEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGH 252
Query: 390 -HPHGHHPHGH 399
H H HGH
Sbjct: 253 AHSHTRGSHGH 263
Score = 36.6 bits (83), Expect = 0.058
Identities = 25/78 (32%), Positives = 26/78 (33%), Gaps = 30/78 (38%)
Query: 366 PHAHHPHEHDTHRQHPHGHHPHGHHP----------------------------HGH-HP 396
PHA PH H T Q HGH G P HGH H
Sbjct: 190 PHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHG 249
Query: 397 HGH-HPHGHHPHCHDFQD 413
HGH H H H H Q+
Sbjct: 250 HGHAHSHTRGSHGHGRQE 267
Score = 31.6 bits (70), Expect = 1.9
Identities = 22/73 (30%), Positives = 22/73 (30%), Gaps = 25/73 (34%)
Query: 357 HEQHPHGHHPHAHHPHEHDTHRQHP-----------------------HGHHPHGH-HPH 392
H PH HH H H Q P H HGH H H
Sbjct: 191 HALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGH 250
Query: 393 GH-HPHGHHPHGH 404
GH H H HGH
Sbjct: 251 GHAHSHTRGSHGH 263
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/96 (37%), Positives = 39/96 (40%), Gaps = 12/96 (12%)
Query: 336 GAQRHSHNNNSSDLHPHKH-HSHEQHPHGH-HPHAH--------HPHEHDTHRQHPHGHH 385
G H++ D H H H HSHE HGH H H H H H HD H H
Sbjct: 29 GGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDL 88
Query: 386 PHGH-HPHGHHPHGHHPHGHHPHCHDFQDYGPCDPP 420
HGH H + H H HG H H H YG P
Sbjct: 89 HHGHSHGYSHESLYHRGHG-HDHEHSHGGYGESGAP 123
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/84 (35%), Positives = 33/84 (39%), Gaps = 16/84 (19%)
Query: 370 HPHEHDTHRQHPHGHHPHGHHPHGHHPHGH-HPHGH--------HPHCHDFQDYGPCDPP 420
H HD ++ HGH H H HGH H HGH H H HD D+G
Sbjct: 31 HDDLHDDLQEDFHGHSHR--HSHEDFHHGHSHAHGHGHTHESIWHGHTHD-HDHG----H 83
Query: 421 PHNQGHCCHGHGPPPGHLRRRGPG 444
H H H HG L RG G
Sbjct: 84 SHEDLHHGHSHGYSHESLYHRGHG 107
Score = 38.9 bits (89), Expect = 0.012
Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 20/71 (28%)
Query: 349 LHPHKHHSHEQHPHGHHPHAHHP------------------HEHDTHRQHPHGH-HPHGH 389
L PH HH+ EQ HGH P + H + HGH H HGH
Sbjct: 193 LEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGH 252
Query: 390 -HPHGHHPHGH 399
H H HGH
Sbjct: 253 AHSHTRGSHGH 263
Score = 36.6 bits (83), Expect = 0.058
Identities = 25/78 (32%), Positives = 26/78 (33%), Gaps = 30/78 (38%)
Query: 366 PHAHHPHEHDTHRQHPHGHHPHGHHP----------------------------HGH-HP 396
PHA PH H T Q HGH G P HGH H
Sbjct: 190 PHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHG 249
Query: 397 HGH-HPHGHHPHCHDFQD 413
HGH H H H H Q+
Sbjct: 250 HGHAHSHTRGSHGHGRQE 267
Score = 31.6 bits (70), Expect = 1.9
Identities = 22/73 (30%), Positives = 22/73 (30%), Gaps = 25/73 (34%)
Query: 357 HEQHPHGHHPHAHHPHEHDTHRQHP-----------------------HGHHPHGH-HPH 392
H PH HH H H Q P H HGH H H
Sbjct: 191 HALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGH 250
Query: 393 GH-HPHGHHPHGH 404
GH H H HGH
Sbjct: 251 GHAHSHTRGSHGH 263
>gi|59938776 cAMP responsive element binding protein 5 isoform delta
[Homo sapiens]
Length = 369
Score = 59.7 bits (143), Expect = 6e-09
Identities = 48/152 (31%), Positives = 60/152 (39%), Gaps = 18/152 (11%)
Query: 333 GTNGAQRHSHNNNSSDLHPHKHHS---HEQHPHGHHPHAHHPHEHDTHRQ-HPHGHHPHG 388
G+ Q H+ +S HPH+H + H +PH H AHHPH H+Q HPH HH H
Sbjct: 124 GSRQDQTPHHHMHS---HPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPH-HHSHS 179
Query: 389 H-HPH-GHHPHGHHPHGH-------HPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLR 439
H H H HH HP H P Q PP G P R
Sbjct: 180 HLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERR 239
Query: 440 RRGPGKG-PRPFHCRQIGSVYRLPPLRKGEVL 470
R+ + CRQ V+ + +K E L
Sbjct: 240 RKFLERNRAAATRCRQKRKVWVMSLEKKAEEL 271
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 10/96 (10%)
Query: 321 PMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKH-HSHEQHPHGHHPHAHHPHEHDTHRQ 379
P + S+ T G S + + H H H H H+ P HHP+ H H+H H
Sbjct: 105 PAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPP-HHPYPHQ-HQHPAHHP 162
Query: 380 HPHGH----HPHGHHPHGH-HPH-GHHPHGHHPHCH 409
HP H HPH HH H H H H HH HP H
Sbjct: 163 HPQPHHQQNHPH-HHSHSHLHAHPAHHQTSPHPPLH 197
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 15/103 (14%)
Query: 350 HPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHP-HGHHPHGH-HPH-GHHP 406
HP + + GH + T H H H PH H HHP+ H H H HHP
Sbjct: 104 HPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSH-PHQHQTLPPHHPYPHQHQHPAHHP 162
Query: 407 HCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRP 449
H P PH+Q + H H H P P
Sbjct: 163 H-----------PQPHHQQNHPHHHSHSHLHAHPAHHQTSPHP 194
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/114 (27%), Positives = 38/114 (33%), Gaps = 28/114 (24%)
Query: 253 NGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHK-PHEHGPPPPPDERDHSHGPP 311
NG +GH G + T HHH H PH+H PP H H P
Sbjct: 110 NGNMNTMGHMMEMMGSRQDQTP-----------HHHMHSHPHQHQTLPPHHPYPHQHQHP 158
Query: 312 LPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPH-KHHSHEQHPHGH 364
H + Q H H+++ S LH H HH HP H
Sbjct: 159 ---------------AHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLH 197
>gi|59938774 cAMP responsive element binding protein 5 isoform beta
[Homo sapiens]
Length = 501
Score = 59.7 bits (143), Expect = 6e-09
Identities = 48/152 (31%), Positives = 60/152 (39%), Gaps = 18/152 (11%)
Query: 333 GTNGAQRHSHNNNSSDLHPHKHHS---HEQHPHGHHPHAHHPHEHDTHRQ-HPHGHHPHG 388
G+ Q H+ +S HPH+H + H +PH H AHHPH H+Q HPH HH H
Sbjct: 256 GSRQDQTPHHHMHS---HPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPH-HHSHS 311
Query: 389 H-HPH-GHHPHGHHPHGH-------HPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLR 439
H H H HH HP H P Q PP G P R
Sbjct: 312 HLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERR 371
Query: 440 RRGPGKG-PRPFHCRQIGSVYRLPPLRKGEVL 470
R+ + CRQ V+ + +K E L
Sbjct: 372 RKFLERNRAAATRCRQKRKVWVMSLEKKAEEL 403
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 10/96 (10%)
Query: 321 PMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKH-HSHEQHPHGHHPHAHHPHEHDTHRQ 379
P + S+ T G S + + H H H H H+ P HHP+ H H+H H
Sbjct: 237 PAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPP-HHPYPHQ-HQHPAHHP 294
Query: 380 HPHGH----HPHGHHPHGH-HPH-GHHPHGHHPHCH 409
HP H HPH HH H H H H HH HP H
Sbjct: 295 HPQPHHQQNHPH-HHSHSHLHAHPAHHQTSPHPPLH 329
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 15/103 (14%)
Query: 350 HPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHP-HGHHPHGH-HPH-GHHP 406
HP + + GH + T H H H PH H HHP+ H H H HHP
Sbjct: 236 HPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSH-PHQHQTLPPHHPYPHQHQHPAHHP 294
Query: 407 HCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRP 449
H P PH+Q + H H H P P
Sbjct: 295 H-----------PQPHHQQNHPHHHSHSHLHAHPAHHQTSPHP 326
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/114 (27%), Positives = 38/114 (33%), Gaps = 28/114 (24%)
Query: 253 NGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHK-PHEHGPPPPPDERDHSHGPP 311
NG +GH G + T HHH H PH+H PP H H P
Sbjct: 242 NGNMNTMGHMMEMMGSRQDQTP-----------HHHMHSHPHQHQTLPPHHPYPHQHQHP 290
Query: 312 LPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPH-KHHSHEQHPHGH 364
H + Q H H+++ S LH H HH HP H
Sbjct: 291 ---------------AHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLH 329
>gi|59938772 cAMP responsive element binding protein 5 isoform gamma
[Homo sapiens]
Length = 475
Score = 59.7 bits (143), Expect = 6e-09
Identities = 48/152 (31%), Positives = 60/152 (39%), Gaps = 18/152 (11%)
Query: 333 GTNGAQRHSHNNNSSDLHPHKHHS---HEQHPHGHHPHAHHPHEHDTHRQ-HPHGHHPHG 388
G+ Q H+ +S HPH+H + H +PH H AHHPH H+Q HPH HH H
Sbjct: 230 GSRQDQTPHHHMHS---HPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPH-HHSHS 285
Query: 389 H-HPH-GHHPHGHHPHGH-------HPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLR 439
H H H HH HP H P Q PP G P R
Sbjct: 286 HLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERR 345
Query: 440 RRGPGKG-PRPFHCRQIGSVYRLPPLRKGEVL 470
R+ + CRQ V+ + +K E L
Sbjct: 346 RKFLERNRAAATRCRQKRKVWVMSLEKKAEEL 377
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 10/96 (10%)
Query: 321 PMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKH-HSHEQHPHGHHPHAHHPHEHDTHRQ 379
P + S+ T G S + + H H H H H+ P HHP+ H H+H H
Sbjct: 211 PAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPP-HHPYPHQ-HQHPAHHP 268
Query: 380 HPHGH----HPHGHHPHGH-HPH-GHHPHGHHPHCH 409
HP H HPH HH H H H H HH HP H
Sbjct: 269 HPQPHHQQNHPH-HHSHSHLHAHPAHHQTSPHPPLH 303
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 15/103 (14%)
Query: 350 HPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHP-HGHHPHGH-HPH-GHHP 406
HP + + GH + T H H H PH H HHP+ H H H HHP
Sbjct: 210 HPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSH-PHQHQTLPPHHPYPHQHQHPAHHP 268
Query: 407 HCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRP 449
H P PH+Q + H H H P P
Sbjct: 269 H-----------PQPHHQQNHPHHHSHSHLHAHPAHHQTSPHP 300
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/114 (27%), Positives = 38/114 (33%), Gaps = 28/114 (24%)
Query: 253 NGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHK-PHEHGPPPPPDERDHSHGPP 311
NG +GH G + T HHH H PH+H PP H H P
Sbjct: 216 NGNMNTMGHMMEMMGSRQDQTP-----------HHHMHSHPHQHQTLPPHHPYPHQHQHP 264
Query: 312 LPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPH-KHHSHEQHPHGH 364
H + Q H H+++ S LH H HH HP H
Sbjct: 265 ---------------AHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLH 303
>gi|59938770 cAMP responsive element binding protein 5 isoform alpha
[Homo sapiens]
Length = 508
Score = 59.7 bits (143), Expect = 6e-09
Identities = 48/152 (31%), Positives = 60/152 (39%), Gaps = 18/152 (11%)
Query: 333 GTNGAQRHSHNNNSSDLHPHKHHS---HEQHPHGHHPHAHHPHEHDTHRQ-HPHGHHPHG 388
G+ Q H+ +S HPH+H + H +PH H AHHPH H+Q HPH HH H
Sbjct: 263 GSRQDQTPHHHMHS---HPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPH-HHSHS 318
Query: 389 H-HPH-GHHPHGHHPHGH-------HPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLR 439
H H H HH HP H P Q PP G P R
Sbjct: 319 HLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERR 378
Query: 440 RRGPGKG-PRPFHCRQIGSVYRLPPLRKGEVL 470
R+ + CRQ V+ + +K E L
Sbjct: 379 RKFLERNRAAATRCRQKRKVWVMSLEKKAEEL 410
Score = 57.0 bits (136), Expect = 4e-08
Identities = 35/96 (36%), Positives = 42/96 (43%), Gaps = 10/96 (10%)
Query: 321 PMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKH-HSHEQHPHGHHPHAHHPHEHDTHRQ 379
P + S+ T G S + + H H H H H+ P HHP+ H H+H H
Sbjct: 244 PAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPP-HHPYPHQ-HQHPAHHP 301
Query: 380 HPHGH----HPHGHHPHGH-HPH-GHHPHGHHPHCH 409
HP H HPH HH H H H H HH HP H
Sbjct: 302 HPQPHHQQNHPH-HHSHSHLHAHPAHHQTSPHPPLH 336
Score = 41.2 bits (95), Expect = 0.002
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 15/103 (14%)
Query: 350 HPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHP-HGHHPHGH-HPH-GHHP 406
HP + + GH + T H H H PH H HHP+ H H H HHP
Sbjct: 243 HPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSH-PHQHQTLPPHHPYPHQHQHPAHHP 301
Query: 407 HCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRP 449
H P PH+Q + H H H P P
Sbjct: 302 H-----------PQPHHQQNHPHHHSHSHLHAHPAHHQTSPHP 333
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/114 (27%), Positives = 38/114 (33%), Gaps = 28/114 (24%)
Query: 253 NGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHK-PHEHGPPPPPDERDHSHGPP 311
NG +GH G + T HHH H PH+H PP H H P
Sbjct: 249 NGNMNTMGHMMEMMGSRQDQTP-----------HHHMHSHPHQHQTLPPHHPYPHQHQHP 297
Query: 312 LPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPH-KHHSHEQHPHGH 364
H + Q H H+++ S LH H HH HP H
Sbjct: 298 ---------------AHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLH 336
>gi|221316609 sperm-associated cation channel 1 [Homo sapiens]
Length = 780
Score = 58.5 bits (140), Expect = 1e-08
Identities = 52/193 (26%), Positives = 67/193 (34%), Gaps = 36/193 (18%)
Query: 266 GGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPP------- 318
G H++S + HG + + H P E H G LP GP P
Sbjct: 134 GFHQQSDSHYHRGSHHGRPQYLGENLSHYSSGVPHHGEASHHGGSYLPHGPNPYSESFHH 193
Query: 319 -----LLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHE 373
L + QH G H ++ H+ H H + P HH PH
Sbjct: 194 SEASHLSGLQHDESQHHQVPHRGWPHHHQVHHHGRSRHHEAHQHGKSP--HHGETISPHS 251
Query: 374 ---------HDTHRQHPHG-HHPHGHHPHGHHPH--GHHPHGHHPH--CHDFQDYGPCDP 419
D H ++ G HHP +H HG HPH HH H H H H QD+
Sbjct: 252 SVGSYQRGISDYHSEYHQGDHHPSEYH-HGDHPHHTQHHYHQTHRHRDYHQHQDH----- 305
Query: 420 PPHNQGHCCHGHG 432
H H + HG
Sbjct: 306 --HGAYHSSYLHG 316
Score = 55.8 bits (133), Expect = 9e-08
Identities = 45/171 (26%), Positives = 59/171 (34%), Gaps = 43/171 (25%)
Query: 258 HLGHPFHWGG--HERSSTTKPPFK--PHGSRDHHHP----HKPHEHGPPPPPDERDHSHG 309
H H G H+ S + P + PH + HHH H+ H+HG P E H
Sbjct: 192 HHSEASHLSGLQHDESQHHQVPHRGWPHHHQVHHHGRSRHHEAHQHGKSPHHGETISPHS 251
Query: 310 PPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAH 369
+ G+ + ++ S+ H HH E H HG HPH
Sbjct: 252 ------------------------SVGSYQRGISDYHSEYHQGDHHPSEYH-HGDHPHHT 286
Query: 370 HPHEHDTHRQHP-HGHHPHGHHPHGHHPHGHH---------PHGHHPHCHD 410
H H THR H H H H + HG + PH HD
Sbjct: 287 QHHYHQTHRHRDYHQHQDHHGAYHSSYLHGDYVQSTSQLSIPHTSRSLIHD 337
Score = 48.9 bits (115), Expect = 1e-05
Identities = 59/233 (25%), Positives = 78/233 (33%), Gaps = 78/233 (33%)
Query: 270 RSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQH 329
RS ++ P +P SR HH ++ H HG P +R SH PP Q + SS H
Sbjct: 24 RSHSSPPHHRPGHSRALHH-YELHHHGVP---HQRGESHHPPEFQD---FHDQALSSHVH 76
Query: 330 ATFGTNGAQRH-------------------SHNNNSSDLHPH------KHHSHEQHPHGH 364
+ + A+ H SH + D H +HH Q+ H
Sbjct: 77 QSHHHSEARNHGRAHGPTGFGLAPSQGAVPSHRSYGEDYHDELQRDGRRHHDGSQYGGFH 136
Query: 365 -------HPHAHH-----------------PH----EHDTHRQHPHGHHPHG---HHPHG 393
H +HH PH H PHG +P+ HH
Sbjct: 137 QQSDSHYHRGSHHGRPQYLGENLSHYSSGVPHHGEASHHGGSYLPHGPNPYSESFHHSEA 196
Query: 394 HHPHG-------HH--PHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGH 437
H G HH PH PH H +G ++ H H HG P H
Sbjct: 197 SHLSGLQHDESQHHQVPHRGWPHHHQVHHHG------RSRHHEAHQHGKSPHH 243
Score = 35.8 bits (81), Expect = 0.099
Identities = 25/89 (28%), Positives = 29/89 (32%), Gaps = 11/89 (12%)
Query: 337 AQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHP--HEHDTHRQHPHGHHP-------- 386
AQ + NN+ D H S H GH HH H H Q HHP
Sbjct: 10 AQNEADTNNA-DRFFRSHSSPPHHRPGHSRALHHYELHHHGVPHQRGESHHPPEFQDFHD 68
Query: 387 HGHHPHGHHPHGHHPHGHHPHCHDFQDYG 415
H H H H +H H +G
Sbjct: 69 QALSSHVHQSHHHSEARNHGRAHGPTGFG 97
Score = 35.0 bits (79), Expect = 0.17
Identities = 37/139 (26%), Positives = 45/139 (32%), Gaps = 40/139 (28%)
Query: 334 TNGAQRHSHNNNSSDLHPHKH----HSHEQHPHGHHPH----AHHP-------------H 372
TN A R +++S H H H +E H HG PH +HHP H
Sbjct: 16 TNNADRFFRSHSSPPHHRPGHSRALHHYELHHHGV-PHQRGESHHPPEFQDFHDQALSSH 74
Query: 373 EHDTH-----RQHPHGHHPHG------------HHPHGHHPHGHHPHGHHPHCHDFQDYG 415
H +H R H H P G H +G H H HD YG
Sbjct: 75 VHQSHHHSEARNHGRAHGPTGFGLAPSQGAVPSHRSYGEDYHDELQRDGRRH-HDGSQYG 133
Query: 416 PCDPPPHNQGHCCHGHGPP 434
+ H HG P
Sbjct: 134 GFHQQSDSHYHRGSHHGRP 152
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 57.4 bits (137), Expect = 3e-08
Identities = 76/253 (30%), Positives = 81/253 (32%), Gaps = 97/253 (38%)
Query: 256 PPHLGHPFHW--------GGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERD-- 305
PP G PF W GG R P H R ++P PPPPP R
Sbjct: 672 PPRGGDPF-WDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEP----PPPPPPFRGAR 726
Query: 306 ---HSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNN----NSSDLHPHKHHSHE 358
GPP +G P G G + H NSS PH
Sbjct: 727 GGRSGGGPPNGRGGPG----------GGMVGGGGHRPHEGPGGGMGNSSGHRPH------ 770
Query: 359 QHPHGHHPHAHHPHEHDT--------HRQHP---------HGHHPH-----------GHH 390
+ P G H PHE HR H GH PH GH
Sbjct: 771 EGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHR 830
Query: 391 PH-----------GHHPH---GHH-PHGHHPHCHDFQDYGPCDPPPHNQGHCCHGH-GPP 434
PH GH PH GH PHGH PH D P GH H H GPP
Sbjct: 831 PHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPH----------DVP----GHRGHDHRGPP 876
Query: 435 P-GHLRRRGPGKG 446
P H GPG G
Sbjct: 877 PHEHRGHDGPGHG 889
Score = 56.6 bits (135), Expect = 5e-08
Identities = 61/213 (28%), Positives = 71/213 (33%), Gaps = 38/213 (17%)
Query: 254 GVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHE---------HGPPPPPDER 304
G PP+ G GG +P P G + H+PHE H P P
Sbjct: 732 GGPPN-GRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGS 790
Query: 305 DHSHGPPLP-QGPPPLLPMSCSSCQH----ATFGTNGAQRHSHNNNSSDLHPHKHHSHEQ 359
G P +GP + H G G R S H HE
Sbjct: 791 MGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEG 850
Query: 360 HPHGHHPHAHHPHEHDTHRQHPH-GHHPHGHHPH--------GHHPH-GHHPHG----HH 405
HG PH H PH+ HR H H G PH H H GH H G H HG +
Sbjct: 851 PGHGG-PHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGGDMSNR 909
Query: 406 PHCHDFQDYGPCDPPPHNQGHCCHGH----GPP 434
P C F G C + +C H GPP
Sbjct: 910 PVCRHFMMKGNC----RYENNCAFYHPGVNGPP 938
Score = 37.0 bits (84), Expect = 0.044
Identities = 36/136 (26%), Positives = 47/136 (34%), Gaps = 21/136 (15%)
Query: 252 INGVPPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHE---------HGPPPPPD 302
I+G H H GG +P P GS H+PHE H P P
Sbjct: 807 ISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPG 866
Query: 303 ERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQ-RHSHNNNSSDLHPHKHH------ 355
R H H +GPPP H G G HSH + S+ +H
Sbjct: 867 HRGHDH-----RGPPPHEHRGHDGPGHGGGGHRGHDGGHSHGGDMSNRPVCRHFMMKGNC 921
Query: 356 SHEQHPHGHHPHAHHP 371
+E + +HP + P
Sbjct: 922 RYENNCAFYHPGVNGP 937
Score = 30.8 bits (68), Expect = 3.2
Identities = 28/84 (33%), Positives = 31/84 (36%), Gaps = 2/84 (2%)
Query: 381 PHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGPPP-GHLR 439
P G H P G PHG + GP PPP G G P G
Sbjct: 634 PGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGP-PPPPRGGDPFWDGPGDPMRGGPM 692
Query: 440 RRGPGKGPRPFHCRQIGSVYRLPP 463
R GPG GP P+H + G PP
Sbjct: 693 RGGPGPGPGPYHRGRGGRGGNEPP 716
>gi|61966923 forkhead box B2 [Homo sapiens]
Length = 432
Score = 56.6 bits (135), Expect = 5e-08
Identities = 46/143 (32%), Positives = 54/143 (37%), Gaps = 39/143 (27%)
Query: 368 AHHPHEHDTHRQHPHGHHPHGH-HPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGH 426
A H H H + G P GH HPH HH H HH H HH H + P PPP
Sbjct: 114 ADHTHLHAGSTKSAPGAGPGGHLHPHHHH-HPHHHHHHHAAAHHHHHHHPPQPPP----- 167
Query: 427 CCHGHGPPPGHLRRRGPGKGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANFPSFPLPHHK 486
PPP P P H + ++ PP P P + PS P
Sbjct: 168 ------PPP-----------PPPPH--MVHYFHQQPP-----TAPQPPPHLPSQP----- 198
Query: 487 HPLKPDNQPFPQSVSESCPGKFK 509
P +P Q PQ S PGK +
Sbjct: 199 -PQQPPQQSQPQQPSH--PGKMQ 218
Score = 52.4 bits (124), Expect = 1e-06
Identities = 30/79 (37%), Positives = 31/79 (39%), Gaps = 7/79 (8%)
Query: 350 HPHKHHSHEQH-----PHGH-HPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHG 403
H H H + P GH HPH HH H H H H HH H HHP P P
Sbjct: 116 HTHLHAGSTKSAPGAGPGGHLHPHHHH-HPHHHHHHHAAAHHHHHHHPPQPPPPPPPPPP 174
Query: 404 HHPHCHDFQDYGPCDPPPH 422
H H Q PPPH
Sbjct: 175 HMVHYFHQQPPTAPQPPPH 193
Score = 44.3 bits (103), Expect = 3e-04
Identities = 25/70 (35%), Positives = 27/70 (38%), Gaps = 16/70 (22%)
Query: 256 PPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSH----GPP 311
P H HP H H H + HHH H P + PPPPP H PP
Sbjct: 138 PHHHHHPHHHHHH------------HAAAHHHHHHHPPQPPPPPPPPPPHMVHYFHQQPP 185
Query: 312 LPQGPPPLLP 321
PPP LP
Sbjct: 186 TAPQPPPHLP 195
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 14/89 (15%)
Query: 336 GAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHH 395
G H H+++ HPH HH H H HH H HHP + P H H+ H
Sbjct: 133 GGHLHPHHHH----HPHHHHHH--HAAAHHHHHHHPPQPPPPPPPPPPHMV--HYFHQQP 184
Query: 396 PHGHHPHGHHPHCHDFQDYGPCDPPPHNQ 424
P P H P P PP +Q
Sbjct: 185 PTAPQPPPHLP------SQPPQQPPQQSQ 207
Score = 43.1 bits (100), Expect = 6e-04
Identities = 29/107 (27%), Positives = 34/107 (31%), Gaps = 30/107 (28%)
Query: 268 HERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSC 327
H S+ + P P G HH H PH H H H PP P PPP P
Sbjct: 120 HAGSTKSAPGAGPGGHLHPHHHHHPHHHHHHHAAAHHHHHHHPPQPPPPPPPPP------ 173
Query: 328 QHATFGTNGAQRHSHNNNSSDLHPHK-HHSHEQHPHGHHPHAHHPHE 373
PH H+ H+Q P P H P +
Sbjct: 174 -----------------------PHMVHYFHQQPPTAPQPPPHLPSQ 197
>gi|32698730 nuclear fragile X mental retardation protein
interacting protein 2 [Homo sapiens]
Length = 695
Score = 56.2 bits (134), Expect = 7e-08
Identities = 34/92 (36%), Positives = 40/92 (43%), Gaps = 20/92 (21%)
Query: 351 PHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHD 410
P HHSH H HPH HHP + +Q PH HH H+ +H H HH H HH H
Sbjct: 10 PQHHHSH--H----HPH-HHPQQ---QQQQPHHHH---HYYFYNHSHNHHHHHHHQQPHQ 56
Query: 411 FQDYG-----PCDPPP--HNQGHCCHGHGPPP 435
+ +G P P H Q H H P
Sbjct: 57 YLQHGAEGSPKAQPKPLKHEQKHTLQQHQETP 88
Score = 36.2 bits (82), Expect = 0.075
Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 6/51 (11%)
Query: 339 RHSHNNNSSDLHPHK-----HHSHEQHPHGH-HPHAHHPHEHDTHRQHPHG 383
+H H+++ HP + HH H + + H H H HH H H+ HG
Sbjct: 11 QHHHSHHHPHHHPQQQQQQPHHHHHYYFYNHSHNHHHHHHHQQPHQYLQHG 61
Score = 32.7 bits (73), Expect = 0.83
Identities = 23/89 (25%), Positives = 27/89 (30%), Gaps = 32/89 (35%)
Query: 279 KPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQ 338
KP + HH H H P ++ H H H F
Sbjct: 4 KPGQPQPQHHHSHHHPHHHPQQQQQQPHHH-------------------HHYYF-----Y 39
Query: 339 RHSHNNNSSDLHPHKHHSHEQHPHGHHPH 367
HSHN H HH H Q PH + H
Sbjct: 40 NHSHN--------HHHHHHHQQPHQYLQH 60
Score = 29.3 bits (64), Expect = 9.2
Identities = 21/84 (25%), Positives = 26/84 (30%), Gaps = 25/84 (29%)
Query: 294 EHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHK 353
E P P + HSH P H Q H H++ H H
Sbjct: 2 EEKPGQPQPQHHHSHHHP-----------------HHHPQQQQQQPHHHHHYYFYNHSHN 44
Query: 354 HHSHEQHPHGHHPHAHHPHEHDTH 377
HH HH H PH++ H
Sbjct: 45 HH--------HHHHHQQPHQYLQH 60
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 55.5 bits (132), Expect = 1e-07
Identities = 56/228 (24%), Positives = 69/228 (30%), Gaps = 20/228 (8%)
Query: 228 ALDLESPKNLVINCEVFDPQE-----HENINGVPPHLGHPFHWGGHERSSTTKPPFKPHG 282
+L PK FDP +E + +PP G + +P P
Sbjct: 846 SLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPA 905
Query: 283 SRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSH 342
+ P PPPP + PP P P +P SS T G +
Sbjct: 906 MKFSRSLSVPGSEDIPPPP-----TTSPPEPPYSTPPVP---SSSGRLTPSPRGGPFNPG 957
Query: 343 NNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPH 402
+ P H H H PH HH H P HH H
Sbjct: 958 SGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHH 1017
Query: 403 GHHPHCHDFQDYG-PCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRP 449
H PH + + G P DPPP GP P RG G P P
Sbjct: 1018 AHPPHPPEMETGGSPDDPPPR------LALGPQPSLRGWRGGGPSPTP 1059
Score = 29.3 bits (64), Expect = 9.2
Identities = 33/117 (28%), Positives = 37/117 (31%), Gaps = 18/117 (15%)
Query: 396 PHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRPFHCRQI 455
PH H PH HH P DP G+ G G L P H
Sbjct: 1392 PHHHSPHAHHEPVLRLWGASPPDPARRELGYRA-GLGSQEKSLPASPPAARRSLLH---- 1446
Query: 456 GSVYRLPPLRKGEVLPL-------PEANFPSFPLP-HHKHPLKPDNQPFPQSVSESC 504
RLPP G V PL P A P P P +P+ P E+C
Sbjct: 1447 ----RLPPTAPG-VGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENC 1498
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 55.1 bits (131), Expect = 2e-07
Identities = 81/302 (26%), Positives = 98/302 (32%), Gaps = 42/302 (13%)
Query: 232 ESPKNLVINCEVFDPQEHENINGVPPHLGHPFH---WGGHERSSTTKPPFKPHG------ 282
ESP + N + PQ G P G P GG++ PP KP G
Sbjct: 27 ESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 86
Query: 283 SRDHHHPHKPHEHGPPPPPDERDHSHGPP-LPQGPPPLLPMSCSSCQHATFGTNGAQRHS 341
++ P GPPP D+ PP PQGPPP G
Sbjct: 87 NKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 146
Query: 342 HNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHP 401
N P K + P G+ P G P P G P
Sbjct: 147 GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206
Query: 402 HGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGPPP-----GHLRRRGPGK--GPRPFHCRQ 454
G + P PPP + GPPP R PGK GP P Q
Sbjct: 207 QGGNK---------PQGPPPPGKPQ-----GPPPQGDNKSQSARSPPGKPQGPPP----Q 248
Query: 455 IGSVYRLPPLRKGEVL-PLPEA-NFPSFPLPHHKHPLKPDNQPFPQSVSESCPGKFKSGF 512
G+ + PP G+ P P+ N P P P P KP P PQ S+S + G
Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPP-PQGGSKSRSSRSPPGK 303
Query: 513 PQ 514
PQ
Sbjct: 304 PQ 305
Score = 49.3 bits (116), Expect = 9e-06
Identities = 58/212 (27%), Positives = 70/212 (33%), Gaps = 27/212 (12%)
Query: 246 PQEHENINGVPP--HLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDE 303
PQ G PP P G ++ S+ PP KP G ++P GPPPPP +
Sbjct: 144 PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG-NQPQ--GPPPPPGK 200
Query: 304 RDHSHGPP-----LPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHE 358
GPP PQGPPP G N + S P
Sbjct: 201 ---PQGPPPQGGNKPQGPPP------------PGKPQGPPPQGDNKSQSARSPPGKPQGP 245
Query: 359 QHPHGHHPHAHHPHEHDTHRQHPHG-HHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPC 417
G+ P P P G + P G P G P G P G G
Sbjct: 246 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGGSKSRSSRSPPGKP 304
Query: 418 DPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRP 449
PP G+ G PPPG + P G +P
Sbjct: 305 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 336
Score = 37.4 bits (85), Expect = 0.034
Identities = 30/84 (35%), Positives = 32/84 (38%), Gaps = 12/84 (14%)
Query: 246 PQEHENINGVPPH---LGHPFHWGGHERSSTTKPPFKPHG-----SRDHHHPHKPHEHGP 297
PQ G PP G P G RSS + PP KP G P P
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS-PPGKPQGPPPQGGNQPQGPPPPPGKPQ 326
Query: 298 PPPPDERDHSHGPP---LPQGPPP 318
PPP + GPP PQGPPP
Sbjct: 327 GPPPQGGNKPQGPPPPGKPQGPPP 350
Score = 32.7 bits (73), Expect = 0.83
Identities = 25/85 (29%), Positives = 29/85 (34%), Gaps = 7/85 (8%)
Query: 246 PQEHENINGVPPHLGHPFHWG--GHERSSTTKPPFKPHGSRDHHHPHKPHEHGPP----- 298
PQ G PP G P G + PP KP G PP
Sbjct: 309 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQG 368
Query: 299 PPPDERDHSHGPPLPQGPPPLLPMS 323
PP E ++ GPP P G P P +
Sbjct: 369 PPQQEGNNPQGPPPPAGGNPQQPQA 393
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 53.9 bits (128), Expect = 3e-07
Identities = 63/234 (26%), Positives = 73/234 (31%), Gaps = 58/234 (24%)
Query: 286 HHHPHKPHEH------------------------GPPPPPDERDHSHG-PPLPQGPPPLL 320
HHH H H H GP PPP PP PQ PPPL
Sbjct: 1242 HHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPSLPPPPQQPPPLP 1301
Query: 321 PMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQH 380
+ A ++ + PH+H H HG P P + R
Sbjct: 1302 QLGSIPPPPA--------------SAPPVGPHRHF----HAHGPVP---GPQHYTLGRPG 1340
Query: 381 PHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQG--HCCHGHGPP--PG 436
G HP PHG HP P PP H QG H H P P
Sbjct: 1341 RAPRRGAGGHPQ-FAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPA 1399
Query: 437 HLRRRGPGKGP------RPFHCRQIGSVYR-LPPLRKGEVLPLPEANFPSFPLP 483
GPG P P H + S + +PP LP P + P PLP
Sbjct: 1400 AGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLP 1453
Score = 47.4 bits (111), Expect = 3e-05
Identities = 65/248 (26%), Positives = 80/248 (32%), Gaps = 45/248 (18%)
Query: 289 PHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSD 348
PH+ PPPPP E S P + SS + FG+ +
Sbjct: 1176 PHQRMPPPPPPPPPEEYKSQRP----------VSNSSSFLGSLFGSKRGKGPFQMPPPPT 1225
Query: 349 LHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHP----HGHHPHGHHPHGHHPHGH 404
S H HH H HH H H P G H + G P P +
Sbjct: 1226 GQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGP---APPPY 1282
Query: 405 HPHCHDFQDYGPCDPPPHNQGHCCHGHGPPP----------GHLRRRGPGKGPRPFHCRQ 454
P P PPP Q G PPP H GP GP+ +
Sbjct: 1283 LPPQQPSLPPPPQQPPPLPQ----LGSIPPPPASAPPVGPHRHFHAHGPVPGPQHY---T 1335
Query: 455 IGSVYRLPPLRKGEVLPLPEANFPSFPLPHHKHPLKPDNQPFP-QSVSESCPGKFKSGFP 513
+G R P R+G P F PH +HPL P P S + P K G P
Sbjct: 1336 LGRPGRAP--RRG------AGGHPQF-APHGRHPLHQPTSPLPLYSPAPQHPPAHKQG-P 1385
Query: 514 QVSMFFTH 521
+ +F H
Sbjct: 1386 KHFIFSHH 1393
Score = 42.0 bits (97), Expect = 0.001
Identities = 40/150 (26%), Positives = 53/150 (35%), Gaps = 15/150 (10%)
Query: 246 PQEHENINGVPPH-----LGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPP 300
P H + +G P LG P R + P F PHG H P P P P
Sbjct: 1318 PHRHFHAHGPVPGPQHYTLGRPGR--APRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAP 1375
Query: 301 PDERDHSHGPP--LPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHE 358
H GP + P ++P + ++ + G+ H H + S L PH
Sbjct: 1376 QHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPH-HPQSPLSPHS----P 1430
Query: 359 QHPHGHHPHAHHPHEHDTHRQHPHGHHPHG 388
PH +P P H H P PHG
Sbjct: 1431 IPPHPSYPPLPPPSPHTPHSPLP-PTSPHG 1459
Score = 34.7 bits (78), Expect = 0.22
Identities = 19/61 (31%), Positives = 22/61 (36%)
Query: 261 HPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLL 320
HP H + PP + PH PH PP P H+ GPP PP
Sbjct: 1417 HPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPPGTANPPSAN 1476
Query: 321 P 321
P
Sbjct: 1477 P 1477
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 53.1 bits (126), Expect = 6e-07
Identities = 52/172 (30%), Positives = 60/172 (34%), Gaps = 28/172 (16%)
Query: 297 PPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHK--- 353
PPP P G P P PPP +P + + GT GA H ++ HPH
Sbjct: 244 PPPVPPPGALPPGIP-PAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHS----HPHPFPP 298
Query: 354 --------------HHSHEQHPHG-HHPHAHHPHEHDTHRQHPHGHHPH-GHHPHGHHPH 397
HH PHG HPHA P P PH G P G P
Sbjct: 299 GGMPHPGMSQMQLAHHG----PHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPR 354
Query: 398 GHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRP 449
G H +G PPP H G PP + +RGP PRP
Sbjct: 355 GPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRP 406
Score = 38.5 bits (88), Expect = 0.015
Identities = 24/71 (33%), Positives = 26/71 (36%), Gaps = 2/71 (2%)
Query: 261 HPFHWGGHERSSTTKPPFKPHGSRDHHHPHK--PHEHGPPPPPDERDHSHGPPLPQGPPP 318
HPF GG ++ HG HPH P G PPP H P P G PP
Sbjct: 294 HPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPP 353
Query: 319 LLPMSCSSCQH 329
P S H
Sbjct: 354 RGPPFGSPMGH 364
Score = 33.1 bits (74), Expect = 0.64
Identities = 20/67 (29%), Positives = 24/67 (35%)
Query: 256 PPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQG 315
PP +G P P PHG R PH + PP P + GP P
Sbjct: 346 PPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPR 405
Query: 316 PPPLLPM 322
P P P+
Sbjct: 406 PTPRPPV 412
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 53.1 bits (126), Expect = 6e-07
Identities = 69/256 (26%), Positives = 88/256 (34%), Gaps = 47/256 (18%)
Query: 266 GGHERSSTTKPPFKPHG---SRDHHHPHKPHEHGPP--PPPDERDHSHGPP----LPQGP 316
GG++ T PP KP G + P G P PPP + S GPP P+G
Sbjct: 43 GGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQ 102
Query: 317 PPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDT 376
PP G N +Q + P + + Q P P
Sbjct: 103 PPQ-------------GGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG 149
Query: 377 HRQH---PHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHGP 433
++ P P G P G G+ G PH G + PP G+ GP
Sbjct: 150 NQSQGPPPRPGKPEGPPPQG----GNQSQGPPPH------PGKPEGPPPQGGN--QSQGP 197
Query: 434 PPGHLRRRGPGKGPRPFHCRQIGSVYRLPPLRKG--EVLPLPEANFPSFPLPHHKHPLKP 491
PP R G +GP P Q G+ + PP R G E P N P P PH P P
Sbjct: 198 PP----RPGKPEGPPP----QGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGP 249
Query: 492 DNQPFPQSVSESCPGK 507
Q + PG+
Sbjct: 250 PPQEGNKPQRPPPPGR 265
Score = 51.6 bits (122), Expect = 2e-06
Identities = 68/264 (25%), Positives = 86/264 (32%), Gaps = 44/264 (16%)
Query: 246 PQEHENINGVPPHLGHPFH---WGGHERSSTTKPPFKPHGSRD---HHHPHKPHEHGPP- 298
PQ G PP G P GG++ P KP G + P G P
Sbjct: 62 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPE 121
Query: 299 -PPPDERDHSHGPP----LPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHK 353
PPP + S GPP P+GPPP G N +Q + P +
Sbjct: 122 GPPPQGGNQSQGPPPRPGKPEGPPPQ-------------GGNQSQGPPPRPGKPEGPPPQ 168
Query: 354 HHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQD 413
+ Q P H P G+ G P P G P G +
Sbjct: 169 GGNQSQGPPPHPGKPEGPPPQG-------GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR 221
Query: 414 YGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGKGPRPFHCRQIGSVYRLPPLRKGEVLPLP 473
G + PP G+ G P PG + P +G +P R PP + + P P
Sbjct: 222 PGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKP---------QRPPPPGRPQGPPPP 272
Query: 474 EANFPSFPLPHHKHPLKPDNQPFP 497
N P PLP KP P P
Sbjct: 273 GGN-PQQPLPPPAG--KPQGPPPP 293
Score = 43.5 bits (101), Expect = 5e-04
Identities = 58/208 (27%), Positives = 70/208 (33%), Gaps = 23/208 (11%)
Query: 246 PQEHENINGVPPHLGHPFH---WGGHERSSTTKPPFKPHG------SRDHHHPHKPHEHG 296
PQ G PP G P GG++ P KP G ++ P +P +
Sbjct: 104 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE 163
Query: 297 PPPPPDERDHSHGPP----LPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPH 352
PPP + S GPP P+GPPP G N S P
Sbjct: 164 -GPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP--PQGGNQSQGPPP 220
Query: 353 KHHSHEQHPH--GHHPHAHHPHEHDTHRQHP-HGHHPHGHHPHGHHPHGHHPHGHHPHCH 409
+ E P G+ P PH P G+ P P G P G P G +P
Sbjct: 221 RPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPG-RPQGPPPPGGNPQQP 279
Query: 410 DFQDYG-PCDPPPHNQGHCCHGHGPPPG 436
G P PPP QG H PP G
Sbjct: 280 LPPPAGKPQGPPPPPQGG--RPHRPPQG 305
Score = 33.1 bits (74), Expect = 0.64
Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 12/74 (16%)
Query: 254 GVPPHLGHPFHWGGHERSSTTKPP--FKPHGSRDHH-HPHKP------HEHGPPPPPDER 304
G PPH G P E + +PP +P G +P +P GPPPPP +
Sbjct: 238 GPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPP-QG 296
Query: 305 DHSHGPPLPQGPPP 318
H P PQG PP
Sbjct: 297 GRPHRP--PQGQPP 308
>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
Length = 548
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/233 (28%), Positives = 83/233 (35%), Gaps = 43/233 (18%)
Query: 277 PFKPHGSRDHHHPHKPH-----EHGPPPPPDERDHSHGP---PLPQGPPPLLPMSCSSCQ 328
P P ++D K + E G P P + GP PL P P P + +
Sbjct: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPAN-NPPP 355
Query: 329 HATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHH-PHEHDTHRQHPHGHHPH 387
+ T ++ N+ S+ P+ H H P G H PH P H
Sbjct: 356 PSLMSTTQSRPPWMNSGPSESRPY-HGMHGGGPGGPGGGPHSFPHPL------PSLTGGH 408
Query: 388 GHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQG-HCCHGHGPPP--GHLRRRGPG 444
G HP H+P+G P P PPP NQG H HGPPP +L G
Sbjct: 409 GGHPMQHNPNGPPPPWMQP-----------PPPPMNQGPHPPGHHGPPPMDQYLGSTPVG 457
Query: 445 KGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANFPSFPLPHHKHPLKPDNQPFP 497
G VYRL KG + P P P P P P P + P P
Sbjct: 458 SG-----------VYRLHQ-GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498
Score = 31.6 bits (70), Expect = 1.9
Identities = 24/89 (26%), Positives = 27/89 (30%), Gaps = 28/89 (31%)
Query: 258 HLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPP------------------- 298
H GHP H + P +P + PH P HGPP
Sbjct: 408 HGGHPMQ---HNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464
Query: 299 ------PPPDERDHSHGPPLPQGPPPLLP 321
PPP PP P G PP P
Sbjct: 465 QGKGMMPPPPMGMMPPPPPPPSGQPPPPP 493
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/233 (28%), Positives = 83/233 (35%), Gaps = 43/233 (18%)
Query: 277 PFKPHGSRDHHHPHKPH-----EHGPPPPPDERDHSHGP---PLPQGPPPLLPMSCSSCQ 328
P P ++D K + E G P P + GP PL P P P + +
Sbjct: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPAN-NPPP 355
Query: 329 HATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHH-PHEHDTHRQHPHGHHPH 387
+ T ++ N+ S+ P+ H H P G H PH P H
Sbjct: 356 PSLMSTTQSRPPWMNSGPSESRPY-HGMHGGGPGGPGGGPHSFPHPL------PSLTGGH 408
Query: 388 GHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQG-HCCHGHGPPP--GHLRRRGPG 444
G HP H+P+G P P PPP NQG H HGPPP +L G
Sbjct: 409 GGHPMQHNPNGPPPPWMQP-----------PPPPMNQGPHPPGHHGPPPMDQYLGSTPVG 457
Query: 445 KGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANFPSFPLPHHKHPLKPDNQPFP 497
G VYRL KG + P P P P P P P + P P
Sbjct: 458 SG-----------VYRLHQ-GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498
Score = 31.6 bits (70), Expect = 1.9
Identities = 24/89 (26%), Positives = 27/89 (30%), Gaps = 28/89 (31%)
Query: 258 HLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPP------------------- 298
H GHP H + P +P + PH P HGPP
Sbjct: 408 HGGHPMQ---HNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464
Query: 299 ------PPPDERDHSHGPPLPQGPPPLLP 321
PPP PP P G PP P
Sbjct: 465 QGKGMMPPPPMGMMPPPPPPPSGQPPPPP 493
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/233 (28%), Positives = 83/233 (35%), Gaps = 43/233 (18%)
Query: 277 PFKPHGSRDHHHPHKPH-----EHGPPPPPDERDHSHGP---PLPQGPPPLLPMSCSSCQ 328
P P ++D K + E G P P + GP PL P P P + +
Sbjct: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPAN-NPPP 355
Query: 329 HATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHH-PHEHDTHRQHPHGHHPH 387
+ T ++ N+ S+ P+ H H P G H PH P H
Sbjct: 356 PSLMSTTQSRPPWMNSGPSESRPY-HGMHGGGPGGPGGGPHSFPHPL------PSLTGGH 408
Query: 388 GHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQG-HCCHGHGPPP--GHLRRRGPG 444
G HP H+P+G P P PPP NQG H HGPPP +L G
Sbjct: 409 GGHPMQHNPNGPPPPWMQP-----------PPPPMNQGPHPPGHHGPPPMDQYLGSTPVG 457
Query: 445 KGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANFPSFPLPHHKHPLKPDNQPFP 497
G VYRL KG + P P P P P P P + P P
Sbjct: 458 SG-----------VYRLHQ-GKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498
Score = 31.6 bits (70), Expect = 1.9
Identities = 24/89 (26%), Positives = 27/89 (30%), Gaps = 28/89 (31%)
Query: 258 HLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPP------------------- 298
H GHP H + P +P + PH P HGPP
Sbjct: 408 HGGHPMQ---HNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLH 464
Query: 299 ------PPPDERDHSHGPPLPQGPPPLLP 321
PPP PP P G PP P
Sbjct: 465 QGKGMMPPPPMGMMPPPPPPPSGQPPPPP 493
>gi|83977459 pleckstrin homology-like domain, family A, member 1
[Homo sapiens]
Length = 401
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/122 (29%), Positives = 42/122 (34%), Gaps = 38/122 (31%)
Query: 275 KPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGT 334
+PP +P P + P P P + S P PQ P
Sbjct: 306 QPPSQPQPQ-----PQLQPQPQPQPQPQPQPQSQPQPQPQPKP----------------- 343
Query: 335 NGAQRHSHNNNSSDLHPHKHHSHEQHPHGH-HPHAH-HPHEHDTHRQHPHGHHPHGHHPH 392
LHP+ H HPH H HPH+H HPH H Q PH H PH
Sbjct: 344 ----------QPQQLHPYPH----PHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQPH 389
Query: 393 GH 394
GH
Sbjct: 390 GH 391
Score = 45.4 bits (106), Expect = 1e-04
Identities = 28/65 (43%), Positives = 30/65 (46%), Gaps = 12/65 (18%)
Query: 371 PHEHDTHRQHPHGHHPHGH-HPHGH-HPHGH-HPHGHHPHCHDFQDYGPCDPPPHNQGHC 427
P + P HP+ H HPH H HPH H HPH HPH H P PH Q H
Sbjct: 335 PQPQPQPKPQPQQLHPYPHPHPHPHSHPHSHPHPH-PHPHPHQI-------PHPHPQPHS 386
Query: 428 -CHGH 431
HGH
Sbjct: 387 QPHGH 391
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 19/129 (14%)
Query: 267 GHERSSTTKPPFKPHGSRDHHHPHKPHEHGP----PPPPD----ERDHSHGPPLPQGPPP 318
G S+ T P H HHH H P P PP PD ER H PP P PPP
Sbjct: 645 GAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPP 704
Query: 319 -----------LLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPH 367
LL +SC + + ++ + D+ HK E+ G P
Sbjct: 705 PPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPD 764
Query: 368 AHHPHEHDT 376
+ +T
Sbjct: 765 DDEEEDEET 773
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/191 (27%), Positives = 54/191 (28%), Gaps = 42/191 (21%)
Query: 296 GPPPPPDERDHSHGPPLPQG-----------PPPLLPMSCSSCQH------ATFGTNGAQ 338
G PP GPP P G PP CS+ A G A
Sbjct: 530 GQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAA 589
Query: 339 RHSHNNNSSDLHPHKHHSHEQHPHG----HHPHAHHP-----------HEHDTHRQHPHG 383
S S PH H E G HH A P H PH
Sbjct: 590 AGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHS 649
Query: 384 HHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGP---CDPPPHNQGHCCHGHGPPPGHLRR 440
H HH H HPH HH H H P Q P P P G H PPP
Sbjct: 650 AQTHPHHHH--HPHHHHHHHHPP-----QPPSPLLLLPPQPDEPGSERHHPAPPPPPPPP 702
Query: 441 RGPGKGPRPFH 451
P P H
Sbjct: 703 PPPPLAQHPHH 713
>gi|224548950 hypothetical protein LOC644844 [Homo sapiens]
Length = 82
Score = 51.2 bits (121), Expect = 2e-06
Identities = 36/86 (41%), Positives = 37/86 (43%), Gaps = 26/86 (30%)
Query: 372 HEHDTHRQHPHGH--HPHGHHPHGHHPHGHH-------PHGHHPHCHDFQDYGPCDPPPH 422
H H HP GH P GH P P HH P GH P GPC PPPH
Sbjct: 8 HCHCGGHGHPPGHCGPPPGHGPGPCGPPPHHGPGPCGPPPGHGP--------GPCGPPPH 59
Query: 423 N-QGHCCHGHGPPPGHLRRRGPGKGP 447
+ G C GPPPGH GPG P
Sbjct: 60 HGPGPC----GPPPGH----GPGHPP 77
Score = 42.7 bits (99), Expect = 8e-04
Identities = 34/81 (41%), Positives = 34/81 (41%), Gaps = 21/81 (25%)
Query: 362 HGHHP-HAHHPHEHDTHRQHPHGHH---PHGHHP-HGHHPHGHHPHGHHPHCHDFQDYGP 416
HGH P H P H P HH P G P HG P G PH H P GP
Sbjct: 14 HGHPPGHCGPPPGHGPGPCGPPPHHGPGPCGPPPGHGPGPCGPPPH-HGP--------GP 64
Query: 417 CDPPP-HNQGHCCHGHGPPPG 436
C PPP H GH PPPG
Sbjct: 65 CGPPPGHGPGH------PPPG 79
Score = 36.2 bits (82), Expect = 0.075
Identities = 21/39 (53%), Positives = 22/39 (56%), Gaps = 7/39 (17%)
Query: 418 DPPPHNQGHC-CHGHGPPPGHL---RRRGPGK-GPRPFH 451
DP P +GHC C GHG PPGH GPG GP P H
Sbjct: 2 DPGP--KGHCHCGGHGHPPGHCGPPPGHGPGPCGPPPHH 38
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/67 (35%), Positives = 25/67 (37%), Gaps = 12/67 (17%)
Query: 253 NGVPP-HLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPP 311
+G PP H G P GH PP G H P GPPP H P
Sbjct: 14 HGHPPGHCGPP---PGHGPGPCGPPPHHGPGPCGPPPGHGPGPCGPPP--------HHGP 62
Query: 312 LPQGPPP 318
P GPPP
Sbjct: 63 GPCGPPP 69
Score = 29.6 bits (65), Expect = 7.1
Identities = 26/69 (37%), Positives = 26/69 (37%), Gaps = 7/69 (10%)
Query: 256 PPHLGHPFHWGGHERSSTTKPPFKPHGSRDHHHPHKPHEHGPPP---PPDERDHSHGPPL 312
P GH H GGH P HG P PH HGP P PP GPP
Sbjct: 3 PGPKGH-CHCGGHGHPPGHCGPPPGHGPGPCGPP--PH-HGPGPCGPPPGHGPGPCGPPP 58
Query: 313 PQGPPPLLP 321
GP P P
Sbjct: 59 HHGPGPCGP 67
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 50.1 bits (118), Expect = 5e-06
Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 19/129 (14%)
Query: 267 GHERSSTTKPPFKPHGSRDHHHPHKPHEHGP----PPPPD----ERDHSHGPPLPQGPPP 318
G S+ T P H HHH H P P PP PD ER H PP P PPP
Sbjct: 645 GAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPP 704
Query: 319 -----------LLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPH 367
LL +SC + + ++ + D+ HK E+ G P
Sbjct: 705 PPLAQHPHHRGLLSPGGTSCCYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPD 764
Query: 368 AHHPHEHDT 376
+ +T
Sbjct: 765 DDEEEDEET 773
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/191 (27%), Positives = 54/191 (28%), Gaps = 42/191 (21%)
Query: 296 GPPPPPDERDHSHGPPLPQG-----------PPPLLPMSCSSCQH------ATFGTNGAQ 338
G PP GPP P G PP CS+ A G A
Sbjct: 530 GQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAA 589
Query: 339 RHSHNNNSSDLHPHKHHSHEQHPHG----HHPHAHHP-----------HEHDTHRQHPHG 383
S S PH H E G HH A P H PH
Sbjct: 590 AGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHS 649
Query: 384 HHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGP---CDPPPHNQGHCCHGHGPPPGHLRR 440
H HH H HPH HH H H P Q P P P G H PPP
Sbjct: 650 AQTHPHHHH--HPHHHHHHHHPP-----QPPSPLLLLPPQPDEPGSERHHPAPPPPPPPP 702
Query: 441 RGPGKGPRPFH 451
P P H
Sbjct: 703 PPPPLAQHPHH 713
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 50.1 bits (118), Expect = 5e-06
Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 19/129 (14%)
Query: 267 GHERSSTTKPPFKPHGSRDHHHPHKPHEHGP----PPPPD----ERDHSHGPPLPQGPPP 318
G S+ T P H HHH H P P PP PD ER H PP P PPP
Sbjct: 645 GAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPP 704
Query: 319 -----------LLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPH 367
LL +SC + + ++ + D+ HK E+ G P
Sbjct: 705 PPLAQHPHHRGLLSPGGTSCCYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPD 764
Query: 368 AHHPHEHDT 376
+ +T
Sbjct: 765 DDEEEDEET 773
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/191 (27%), Positives = 54/191 (28%), Gaps = 42/191 (21%)
Query: 296 GPPPPPDERDHSHGPPLPQG-----------PPPLLPMSCSSCQH------ATFGTNGAQ 338
G PP GPP P G PP CS+ A G A
Sbjct: 530 GQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAA 589
Query: 339 RHSHNNNSSDLHPHKHHSHEQHPHG----HHPHAHHP-----------HEHDTHRQHPHG 383
S S PH H E G HH A P H PH
Sbjct: 590 AGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHS 649
Query: 384 HHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGP---CDPPPHNQGHCCHGHGPPPGHLRR 440
H HH H HPH HH H H P Q P P P G H PPP
Sbjct: 650 AQTHPHHHH--HPHHHHHHHHPP-----QPPSPLLLLPPQPDEPGSERHHPAPPPPPPPP 702
Query: 441 RGPGKGPRPFH 451
P P H
Sbjct: 703 PPPPLAQHPHH 713
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/216 (26%), Positives = 70/216 (32%), Gaps = 48/216 (22%)
Query: 282 GSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQ-RH 340
GS H H PPPPP H H PP H + G G Q +H
Sbjct: 1665 GSHIHSQTAGHHLPPPPPPPGPAPHHHPPP-----------------HPSTGLQGLQAQH 1707
Query: 341 SHNNNSSDLHPHKHHSHEQHPHGHHPHA----HHPHEHDTHRQHPHGHHP--------HG 388
H NS+ P GHH + HHP H P HP
Sbjct: 1708 QHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHP-PHQGPPLFPSSAHPTVPPYPSQAT 1766
Query: 389 HHPHGHHPHGHHPHGHHPHC------HDFQDYGPCD-PPPHNQGHCCHGHGPPPGHLRRR 441
HH H P G PHC Q GP P P G C P PG +
Sbjct: 1767 HHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFC-----PHPGSVALP 1821
Query: 442 GPGKGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANF 477
+GP +Q V P+ + +V P + N+
Sbjct: 1822 HGVQGP-----QQASPVPGQIPIHRAQVPPTFQNNY 1852
Score = 40.8 bits (94), Expect = 0.003
Identities = 62/249 (24%), Positives = 71/249 (28%), Gaps = 65/249 (26%)
Query: 278 FKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGA 337
F P + HH PPPPP + GP L Q P
Sbjct: 1609 FLPSQNPTIHHQTAAAVVPPPPPPPP---APGPHLVQQP--------------------- 1644
Query: 338 QRHSHNNNSSDLHPHKHHSHEQHPHGH---HPHAHHPHEHDTHRQHPHGHHPHGHHPHGH 394
+SH+QH H HA P H H Q H P P G
Sbjct: 1645 -----------------NSHQQHSVAHVVGPVHAVTPGSH-IHSQTAGHHLPPPPPPPGP 1686
Query: 395 HPHGHHPHGH---------HPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGK 445
PH HHP H H H P PPP GH P +
Sbjct: 1687 APH-HHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQ 1745
Query: 446 GPRPFHCRQIGSVYRLPPLRKGEVL------PLPEANFPSFPLP---HHKHPLKPDNQPF 496
GP F +V P P P PLP H P P++ P
Sbjct: 1746 GPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPT 1805
Query: 497 PQSVSESCP 505
P + S CP
Sbjct: 1806 P-TASGFCP 1813
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/216 (26%), Positives = 70/216 (32%), Gaps = 48/216 (22%)
Query: 282 GSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGAQ-RH 340
GS H H PPPPP H H PP H + G G Q +H
Sbjct: 1665 GSHIHSQTAGHHLPPPPPPPGPAPHHHPPP-----------------HPSTGLQGLQAQH 1707
Query: 341 SHNNNSSDLHPHKHHSHEQHPHGHHPHA----HHPHEHDTHRQHPHGHHP--------HG 388
H NS+ P GHH + HHP H P HP
Sbjct: 1708 QHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHP-PHQGPPLFPSSAHPTVPPYPSQAT 1766
Query: 389 HHPHGHHPHGHHPHGHHPHC------HDFQDYGPCD-PPPHNQGHCCHGHGPPPGHLRRR 441
HH H P G PHC Q GP P P G C P PG +
Sbjct: 1767 HHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFC-----PHPGSVALP 1821
Query: 442 GPGKGPRPFHCRQIGSVYRLPPLRKGEVLPLPEANF 477
+GP +Q V P+ + +V P + N+
Sbjct: 1822 HGVQGP-----QQASPVPGQIPIHRAQVPPTFQNNY 1852
Score = 40.8 bits (94), Expect = 0.003
Identities = 62/249 (24%), Positives = 71/249 (28%), Gaps = 65/249 (26%)
Query: 278 FKPHGSRDHHHPHKPHEHGPPPPPDERDHSHGPPLPQGPPPLLPMSCSSCQHATFGTNGA 337
F P + HH PPPPP + GP L Q P
Sbjct: 1609 FLPSQNPTIHHQTAAAVVPPPPPPPP---APGPHLVQQP--------------------- 1644
Query: 338 QRHSHNNNSSDLHPHKHHSHEQHPHGH---HPHAHHPHEHDTHRQHPHGHHPHGHHPHGH 394
+SH+QH H HA P H H Q H P P G
Sbjct: 1645 -----------------NSHQQHSVAHVVGPVHAVTPGSH-IHSQTAGHHLPPPPPPPGP 1686
Query: 395 HPHGHHPHGH---------HPHCHDFQDYGPCDPPPHNQGHCCHGHGPPPGHLRRRGPGK 445
PH HHP H H H P PPP GH P +
Sbjct: 1687 APH-HHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQ 1745
Query: 446 GPRPFHCRQIGSVYRLPPLRKGEVL------PLPEANFPSFPLP---HHKHPLKPDNQPF 496
GP F +V P P P PLP H P P++ P
Sbjct: 1746 GPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPT 1805
Query: 497 PQSVSESCP 505
P + S CP
Sbjct: 1806 P-TASGFCP 1813
>gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo
sapiens]
Length = 265
Score = 50.1 bits (118), Expect = 5e-06
Identities = 36/142 (25%), Positives = 48/142 (33%), Gaps = 7/142 (4%)
Query: 296 GPPPPPDERDHS--HGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHK 353
G P+E S H + Q P + S A + T+ + SS+ H
Sbjct: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSE-HGSS 76
Query: 354 HHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQD 413
H+ +H G H + H +H G H G P G P G H G P
Sbjct: 77 KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESG 136
Query: 414 YGPCDPPPHNQGHCCHGHGPPP 435
P D P + HG G P
Sbjct: 137 EQPSDEQPSGE----HGSGEQP 154
Score = 36.2 bits (82), Expect = 0.075
Identities = 19/81 (23%), Positives = 26/81 (32%), Gaps = 5/81 (6%)
Query: 331 TFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHH-----PHEHDTHRQHPHGHH 385
T G + H+ ++ H H+ + P G P H P + P
Sbjct: 84 TSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQ 143
Query: 386 PHGHHPHGHHPHGHHPHGHHP 406
P G H G P G G P
Sbjct: 144 PSGEHGSGEQPSGEQASGEQP 164
>gi|9955927 acrosomal vesicle protein 1 isoform b precursor [Homo
sapiens]
Length = 246
Score = 50.1 bits (118), Expect = 5e-06
Identities = 36/142 (25%), Positives = 48/142 (33%), Gaps = 7/142 (4%)
Query: 296 GPPPPPDERDHS--HGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHK 353
G P+E S H + Q P + S A + T+ + SS+ H
Sbjct: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSE-HGSS 76
Query: 354 HHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQD 413
H+ +H G H + H +H G H G P G P G H G P
Sbjct: 77 KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESG 136
Query: 414 YGPCDPPPHNQGHCCHGHGPPP 435
P D P + HG G P
Sbjct: 137 EQPSDEQPSGE----HGSGEQP 154
Score = 36.6 bits (83), Expect = 0.058
Identities = 24/112 (21%), Positives = 35/112 (31%), Gaps = 17/112 (15%)
Query: 331 TFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHH----------PHEHDTHRQH 380
T G + H+ ++ H H+ + P G P H +
Sbjct: 84 TSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQ 143
Query: 381 PHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHG 432
P G H G P G G P G +C+ ++QG C G G
Sbjct: 144 PSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYM-------NDQGKCLRGEG 188
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.139 0.471
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,027,534
Number of Sequences: 37866
Number of extensions: 2003518
Number of successful extensions: 20319
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 222
Number of HSP's successfully gapped in prelim test: 338
Number of HSP's that attempted gapping in prelim test: 11431
Number of HSP's gapped (non-prelim): 4374
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.