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Search of human proteins with 4504073
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504073 glycoprotein Ib, beta polypeptide precursor [Homo
sapiens]
(206 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504073 glycoprotein Ib, beta polypeptide precursor [Homo sap... 420 e-118
gi|4504077 glycoprotein IX (platelet) precursor [Homo sapiens] 94 8e-20
gi|61966761 leucine rich repeat containing 26 [Homo sapiens] 67 1e-11
gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens] 64 1e-10
gi|13194201 reticulon 4 receptor precursor [Homo sapiens] 62 3e-10
gi|198041768 synleurin [Homo sapiens] 60 1e-09
gi|157426829 leucine rich repeat and Ig domain containing 3 [Hom... 59 2e-09
gi|76880480 hypothetical protein LOC9865 [Homo sapiens] 58 5e-09
gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 57 8e-09
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens] 56 2e-08
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 56 2e-08
gi|194306623 immunoglobulin superfamily containing leucine-rich ... 56 2e-08
gi|194306621 immunoglobulin superfamily containing leucine-rich ... 56 2e-08
gi|39930401 immunoglobulin superfamily containing leucine-rich r... 56 2e-08
gi|194306618 immunoglobulin superfamily containing leucine-rich ... 56 2e-08
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 56 2e-08
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 55 5e-08
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 55 5e-08
gi|40217825 slit and trk like 6 [Homo sapiens] 54 9e-08
gi|27436867 slit and trk like 4 protein [Homo sapiens] 54 9e-08
gi|4759146 slit homolog 2 [Homo sapiens] 54 1e-07
gi|40217817 slit and trk like 1 protein [Homo sapiens] 54 1e-07
gi|52353306 leucine rich repeat containing 55 [Homo sapiens] 53 2e-07
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens] 52 3e-07
gi|51317373 netrin-G1 ligand [Homo sapiens] 52 4e-07
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 52 5e-07
gi|239752702 PREDICTED: leucine rich repeat containing 38, parti... 51 6e-07
gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo ... 51 6e-07
gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo ... 51 6e-07
gi|188528675 slit homolog 1 [Homo sapiens] 51 8e-07
>gi|4504073 glycoprotein Ib, beta polypeptide precursor [Homo
sapiens]
Length = 206
Score = 420 bits (1079), Expect = e-118
Identities = 206/206 (100%), Positives = 206/206 (100%)
Query: 1 MGSGPRGALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTEL 60
MGSGPRGALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTEL
Sbjct: 1 MGSGPRGALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTEL 60
Query: 61 VLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVA 120
VLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVA
Sbjct: 61 VLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVA 120
Query: 121 PPALRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLLCRLRRLRA 180
PPALRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLLCRLRRLRA
Sbjct: 121 PPALRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLLCRLRRLRA 180
Query: 181 RARARAAARLSLTDPLVAERAGTDES 206
RARARAAARLSLTDPLVAERAGTDES
Sbjct: 181 RARARAAARLSLTDPLVAERAGTDES 206
>gi|4504077 glycoprotein IX (platelet) precursor [Homo sapiens]
Length = 177
Score = 94.0 bits (232), Expect = 8e-20
Identities = 63/167 (37%), Positives = 80/167 (47%), Gaps = 16/167 (9%)
Query: 13 LLLLAPPSRPAAGCPAPCSCA-----GTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNL 67
L LL + CP+PC+C G VDC GLT +LP A P T L+L N+L
Sbjct: 7 LFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLT--ALP-ALPARTRHLLLANNSL 63
Query: 68 TALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVAPPALR-- 125
++PPG D LP L+T + NPW CDC L LR WL R A +RC +P
Sbjct: 64 QSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEA-LLQVRCASPSLAAHG 122
Query: 126 --GRLLPYLAED---ELRAACAPGPLCWGALAAQLALLGLGLLHALL 167
GRL Y +L+A+ + W +A LGL LL LL
Sbjct: 123 PLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLL 169
>gi|61966761 leucine rich repeat containing 26 [Homo sapiens]
Length = 334
Score = 67.0 bits (162), Expect = 1e-11
Identities = 70/187 (37%), Positives = 77/187 (41%), Gaps = 13/187 (6%)
Query: 7 GALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRR--GLTWASLPTAFPVDTTELVLTG 64
GAL LL L A G AP L G R L A+L A P+ L L
Sbjct: 119 GALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALG-ALPL-LRSLSLQD 176
Query: 65 NNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRD-LRCVAPPA 123
N L AL PGLL LPAL HL NPW C C L PL AWL P A + + CV P
Sbjct: 177 NELAALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHPLPASEAETVLCVWPGR 236
Query: 124 LRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLL------CRLRR 177
L L P A + + PL LA L L +L L L CR RR
Sbjct: 237 L--TLSPLTAFSDAAFSHCAQPLALRDLAVVYTLGPASFLVSLASCLALGSGLTACRARR 294
Query: 178 LRARARA 184
R R A
Sbjct: 295 RRLRTAA 301
Score = 38.1 bits (87), Expect = 0.005
Identities = 33/101 (32%), Positives = 41/101 (40%), Gaps = 16/101 (15%)
Query: 3 SGPRGALSLLLLLLAPP-------------SRPAAGCPAPCSCA-GTLVDCGRRGLTWAS 48
S PR L LLLLL P S A CP C+C G L C L+ +
Sbjct: 7 SRPRPLLLLLLLLSPWPVWAQVSATASPSGSLGAPDCPEVCTCVPGGLASCS--ALSLPA 64
Query: 49 LPTAFPVDTTELVLTGNNLTALPPGLLDALPALRTAHLGAN 89
+P + L+L N + ALPPG AL+ L N
Sbjct: 65 VPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLREN 105
>gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]
Length = 420
Score = 63.5 bits (153), Expect = 1e-10
Identities = 37/86 (43%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 58 TELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLR 117
T L L N+L +LP L LP+L L ANPW CDCR PL AW + R D+
Sbjct: 230 TILYLFNNSLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAWF--QRARVSSSDVT 287
Query: 118 CVAPPALRGRLLPYLAEDELRAACAP 143
C PP +GR L L E + + AC P
Sbjct: 288 CATPPERQGRDLRALREADFQ-ACPP 312
Score = 38.5 bits (88), Expect = 0.004
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 5 PRGALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTG 64
P A LL+LL P + P+ CP C+C + + ++S+P + P T L L
Sbjct: 12 PASACLLLMLLALPLAAPS--CPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQRLFLQN 69
Query: 65 NNLTALPPG 73
N + L PG
Sbjct: 70 NLIRTLRPG 78
>gi|13194201 reticulon 4 receptor precursor [Homo sapiens]
Length = 473
Score = 62.4 bits (150), Expect = 3e-10
Identities = 44/104 (42%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L NNL+ALP L L AL+ L NPW CDCR PL AWL + R ++ C
Sbjct: 231 LYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCRARPLWAWL--QKFRGSSSEVPCS 288
Query: 120 APPALRGRLLPYLAEDELR-AACAPGPL--CWGALAAQLALLGL 160
P L GR L LA ++L+ A A GP W A LGL
Sbjct: 289 LPQRLAGRDLKRLAANDLQGCAVATGPYHPIWTGRATDEEPLGL 332
>gi|198041768 synleurin [Homo sapiens]
Length = 622
Score = 60.5 bits (145), Expect = 1e-09
Identities = 32/73 (43%), Positives = 44/73 (60%), Gaps = 3/73 (4%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L+ NNLTAL P +L L +L +NPW C+C+L+ LR WLA A ++ C
Sbjct: 330 LNLSFNNLTALHPRVLKPLSSLIHLQANSNPWECNCKLLGLRDWLA---SSAITLNIYCQ 386
Query: 120 APPALRGRLLPYL 132
PP++RGR L Y+
Sbjct: 387 NPPSMRGRALRYI 399
Score = 41.2 bits (95), Expect = 6e-04
Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 12 LLLLLAPPSRPAAGCPAPCS-CAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTAL 70
LLLLL + GC + C C G ++C GL+ S+P FP T L LTGNN++ +
Sbjct: 21 LLLLL---HKEILGCSSVCQLCTGRQINCRNLGLS--SIPKNFPESTVFLYLTGNNISYI 75
Query: 71 PPGLLDALPALRTAHL 86
L L +L +L
Sbjct: 76 NESELTGLHSLVALYL 91
>gi|157426829 leucine rich repeat and Ig domain containing 3 [Homo
sapiens]
Length = 592
Score = 59.3 bits (142), Expect = 2e-09
Identities = 39/84 (46%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
Query: 8 ALSLLLLLLAPPSRPAAGCPAPCSCA--GTLVDCGRRGLTWASLPTAFPVDTTELVLTGN 65
+L LLLL APP PA GCPA C C V C RR LT ++P P +T L L+ N
Sbjct: 9 SLPLLLLPAAPP--PAGGCPARCECTVQTRAVACTRRRLT--AVPDGIPAETRLLELSRN 64
Query: 66 NLTALPPGLLDALPALRTAHLGAN 89
+ L PG L ALPAL L N
Sbjct: 65 RIRCLNPGDLAALPALEELDLSEN 88
Score = 35.0 bits (79), Expect = 0.045
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 6/80 (7%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPY--RDLR 117
L L+ N L+ L ++ L T + NP CDCRL+ W+ R + + R
Sbjct: 323 LNLSNNLLSTLEESTFHSVNTLETLRVDGNPLACDCRLL----WIVQRRKTLNFDGRLPA 378
Query: 118 CVAPPALRGRLLPYLAEDEL 137
C P +RG L L + L
Sbjct: 379 CATPAEVRGDALRNLPDSVL 398
>gi|76880480 hypothetical protein LOC9865 [Homo sapiens]
Length = 811
Score = 58.2 bits (139), Expect = 5e-09
Identities = 36/91 (39%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
Query: 59 ELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDL-- 116
EL L N L+AL + A PAL L N W CDCRL L+ W+ + +
Sbjct: 329 ELSLRNNALSALSGDIFAASPALYRLDLDGNGWTCDCRLRGLKRWMGDWHSQGRLLTVFV 388
Query: 117 RCVAPPALRGRLLPYLAEDELR-AACA-PGP 145
+C PPALRG+ L YL + +L+ +CA P P
Sbjct: 389 QCRHPPALRGKYLDYLDDQQLQNGSCADPSP 419
>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
Length = 513
Score = 57.4 bits (137), Expect = 8e-09
Identities = 39/84 (46%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Query: 9 LSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLT 68
L LLLLLL P R AAGCPA C C V+CG L +P P T L L NN+
Sbjct: 9 LPLLLLLL--PLR-AAGCPAACRCYSATVECG--ALRLRVVPLGIPPGTQTLFLQDNNIA 63
Query: 69 ALPPGLLDALPALRTAHLGANPWR 92
L PG L L ALR +L N R
Sbjct: 64 RLEPGALAPLAALRRLYLHNNSLR 87
Score = 43.1 bits (100), Expect = 2e-04
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPER---APYRDL 116
L L+ N L + L L +L+ L NPWRCDC L L AW+ +R + R +
Sbjct: 175 LDLSRNQLGTISREALQPLASLQVLRLTENPWRCDCALHWLGAWIKEGGQRLLTSRDRKI 234
Query: 117 RCVAPPAL 124
C PP L
Sbjct: 235 MCAEPPRL 242
Score = 33.5 bits (75), Expect = 0.13
Identities = 27/63 (42%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 121 PPALRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLLCRLRRLRA 180
PPA R E A A G A+AA +ALL L ALLLV ++CR RR R
Sbjct: 377 PPAARPAGSEPRPEAGSMAFRALGVATQTAIAAAIALLALT---ALLLVAMICRRRRRRK 433
Query: 181 RAR 183
+AR
Sbjct: 434 KAR 436
>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
Length = 545
Score = 56.2 bits (134), Expect = 2e-08
Identities = 30/78 (38%), Positives = 39/78 (50%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L+ N LT LP G+ D L L NPW+CDC L L WL +R C
Sbjct: 366 LSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTYCA 425
Query: 120 APPALRGRLLPYLAEDEL 137
P L+G+++P L E +L
Sbjct: 426 GPAYLKGQVVPALNEKQL 443
Score = 31.2 bits (69), Expect = 0.65
Identities = 22/69 (31%), Positives = 30/69 (43%), Gaps = 5/69 (7%)
Query: 13 LLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPP 72
LLLLA P++P CP C C V C L A++P P T ++ + T L
Sbjct: 12 LLLLARPAQP---CPMGCDCFVQEVFCSDEEL--ATVPLDIPPYTKNIIFVETSFTTLET 66
Query: 73 GLLDALPAL 81
+ P L
Sbjct: 67 RAFGSNPNL 75
Score = 28.5 bits (62), Expect = 4.2
Identities = 15/31 (48%), Positives = 17/31 (54%)
Query: 59 ELVLTGNNLTALPPGLLDALPALRTAHLGAN 89
+L L N L ALP GL L AL + HL N
Sbjct: 125 KLTLNFNMLEALPEGLFQHLAALESLHLQGN 155
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 55.8 bits (133), Expect = 2e-08
Identities = 36/84 (42%), Positives = 46/84 (54%), Gaps = 5/84 (5%)
Query: 9 LSLLLLLLAPPSR---PAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGN 65
L LLLL L P + P A C A C+CAG +DCG RGL A+LP P T L L+ N
Sbjct: 21 LWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLDCGGRGL--AALPGDLPSWTRSLNLSYN 78
Query: 66 NLTALPPGLLDALPALRTAHLGAN 89
L+ + P + LP L+ +L N
Sbjct: 79 KLSEIDPAGFEDLPNLQEVYLNNN 102
Score = 35.0 bits (79), Expect = 0.045
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 1/68 (1%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L GN + ++ + L+ H+ ++ + CDC+L L WL GR +A + C
Sbjct: 411 LNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWLIGRMLQA-FVTATCA 469
Query: 120 APPALRGR 127
P +L+G+
Sbjct: 470 HPESLKGQ 477
>gi|194306623 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 55.8 bits (133), Expect = 2e-08
Identities = 31/72 (43%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 56 DTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRD 115
D L + N L L PG DAL AL L NP+ C C LV L+AW A P D
Sbjct: 148 DLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPD 207
Query: 116 -LRCVAPPALRG 126
+ C +PPAL+G
Sbjct: 208 SIACASPPALQG 219
Score = 35.8 bits (81), Expect = 0.026
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 10/92 (10%)
Query: 5 PRGALSLLLLLLAPPSRPAAGCPAPCSC----AGTLVDCGRRGLTWASLPTAFPVDTTEL 60
P AL L+ LL A CP PC+C A DC + L +P P + T L
Sbjct: 3 PLRALWLVWALLGV----AGSCPEPCACVDKYAHQFADCAYKEL--REVPEGLPANVTTL 56
Query: 61 VLTGNNLTALPPGLLDALPALRTAHLGANPWR 92
L+ N +T L G + + + L N R
Sbjct: 57 SLSANKITVLRRGAFADVTQVTSLWLAHNEVR 88
>gi|194306621 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 55.8 bits (133), Expect = 2e-08
Identities = 31/72 (43%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 56 DTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRD 115
D L + N L L PG DAL AL L NP+ C C LV L+AW A P D
Sbjct: 148 DLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPD 207
Query: 116 -LRCVAPPALRG 126
+ C +PPAL+G
Sbjct: 208 SIACASPPALQG 219
Score = 35.8 bits (81), Expect = 0.026
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 10/92 (10%)
Query: 5 PRGALSLLLLLLAPPSRPAAGCPAPCSC----AGTLVDCGRRGLTWASLPTAFPVDTTEL 60
P AL L+ LL A CP PC+C A DC + L +P P + T L
Sbjct: 3 PLRALWLVWALLGV----AGSCPEPCACVDKYAHQFADCAYKEL--REVPEGLPANVTTL 56
Query: 61 VLTGNNLTALPPGLLDALPALRTAHLGANPWR 92
L+ N +T L G + + + L N R
Sbjct: 57 SLSANKITVLRRGAFADVTQVTSLWLAHNEVR 88
>gi|39930401 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 55.8 bits (133), Expect = 2e-08
Identities = 31/72 (43%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 56 DTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRD 115
D L + N L L PG DAL AL L NP+ C C LV L+AW A P D
Sbjct: 148 DLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPD 207
Query: 116 -LRCVAPPALRG 126
+ C +PPAL+G
Sbjct: 208 SIACASPPALQG 219
Score = 35.8 bits (81), Expect = 0.026
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 10/92 (10%)
Query: 5 PRGALSLLLLLLAPPSRPAAGCPAPCSC----AGTLVDCGRRGLTWASLPTAFPVDTTEL 60
P AL L+ LL A CP PC+C A DC + L +P P + T L
Sbjct: 3 PLRALWLVWALLGV----AGSCPEPCACVDKYAHQFADCAYKEL--REVPEGLPANVTTL 56
Query: 61 VLTGNNLTALPPGLLDALPALRTAHLGANPWR 92
L+ N +T L G + + + L N R
Sbjct: 57 SLSANKITVLRRGAFADVTQVTSLWLAHNEVR 88
>gi|194306618 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 55.8 bits (133), Expect = 2e-08
Identities = 31/72 (43%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 56 DTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRD 115
D L + N L L PG DAL AL L NP+ C C LV L+AW A P D
Sbjct: 148 DLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPD 207
Query: 116 -LRCVAPPALRG 126
+ C +PPAL+G
Sbjct: 208 SIACASPPALQG 219
Score = 35.8 bits (81), Expect = 0.026
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 10/92 (10%)
Query: 5 PRGALSLLLLLLAPPSRPAAGCPAPCSC----AGTLVDCGRRGLTWASLPTAFPVDTTEL 60
P AL L+ LL A CP PC+C A DC + L +P P + T L
Sbjct: 3 PLRALWLVWALLGV----AGSCPEPCACVDKYAHQFADCAYKEL--REVPEGLPANVTTL 56
Query: 61 VLTGNNLTALPPGLLDALPALRTAHLGANPWR 92
L+ N +T L G + + + L N R
Sbjct: 57 SLSANKITVLRRGAFADVTQVTSLWLAHNEVR 88
>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
sapiens]
Length = 674
Score = 55.8 bits (133), Expect = 2e-08
Identities = 30/67 (44%), Positives = 34/67 (50%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L+ NNLT LP GL D L L L NPW C C L+ LR W+ R R L C
Sbjct: 299 LDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQ 358
Query: 120 APPALRG 126
P +RG
Sbjct: 359 GPEKVRG 365
Score = 35.8 bits (81), Expect = 0.026
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 26 CPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNL 67
CP+ C C + C RGLT S+P P D T L L N +
Sbjct: 54 CPSVCRCDNGFIYCNDRGLT--SIPADIPDDATTLYLQNNQI 93
>gi|38202222 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 54.7 bits (130), Expect = 5e-08
Identities = 26/67 (38%), Positives = 36/67 (53%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L ++ NNL+ LP G+ D L + L NPW C C++ +R WL P + R L C
Sbjct: 276 LDMSNNNLSNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQ 335
Query: 120 APPALRG 126
AP +RG
Sbjct: 336 APEKVRG 342
Score = 42.7 bits (99), Expect = 2e-04
Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
Query: 12 LLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGN--NLTA 69
L L +AP S A CP+ C C + C R LT S+PT P D T L L N N
Sbjct: 17 LFLQVAPLSVMAKSCPSVCRCDAGFIYCNDRFLT--SIPTGIPEDATTLYLQNNQINNAG 74
Query: 70 LPPGLLDALPALR 82
+P L + L R
Sbjct: 75 IPSDLKNLLKVER 87
>gi|7019383 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 54.7 bits (130), Expect = 5e-08
Identities = 26/67 (38%), Positives = 36/67 (53%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L ++ NNL+ LP G+ D L + L NPW C C++ +R WL P + R L C
Sbjct: 276 LDMSNNNLSNLPQGIFDDLDNITQLILRNNPWYCGCKMKWVRDWLQSLPVKVNVRGLMCQ 335
Query: 120 APPALRG 126
AP +RG
Sbjct: 336 APEKVRG 342
Score = 42.7 bits (99), Expect = 2e-04
Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
Query: 12 LLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGN--NLTA 69
L L +AP S A CP+ C C + C R LT S+PT P D T L L N N
Sbjct: 17 LFLQVAPLSVMAKSCPSVCRCDAGFIYCNDRFLT--SIPTGIPEDATTLYLQNNQINNAG 74
Query: 70 LPPGLLDALPALR 82
+P L + L R
Sbjct: 75 IPSDLKNLLKVER 87
>gi|40217825 slit and trk like 6 [Homo sapiens]
Length = 841
Score = 53.9 bits (128), Expect = 9e-08
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 55 VDTTELVLTGNNLTALP-PGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPY 113
V T L L GN L LP G L+ + + L N W C+C L+ L+ WL P ++
Sbjct: 183 VPLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWLENMPPQSII 242
Query: 114 RDLRCVAPPALRGRLLPYLAEDEL 137
D+ C +PP +G +L L ++ +
Sbjct: 243 GDVVCNSPPFFKGSILSRLKKESI 266
Score = 43.1 bits (100), Expect = 2e-04
Identities = 28/84 (33%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Query: 55 VDTTELVLTGNNLTALP-PGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPY 113
V T++ L N T LP +LD L L L NPW C C LV L+ W+ +
Sbjct: 482 VPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNPWDCSCDLVGLQQWIQKLSKNTVT 541
Query: 114 RDLRCVAPPALRGRLLPYLAEDEL 137
D+ C +P L + L L + L
Sbjct: 542 DDILCTSPGHLDKKELKALNSEIL 565
Score = 37.4 bits (85), Expect = 0.009
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 5 PRGALSLLLLLLAPPSR-PAAGCPAPCSC-----AGTLVDCGRRGLTWASLPTAFPVDTT 58
P A L+ + P ++ P CP PC+C +G L+ C R + S P +
Sbjct: 307 PTKAPGLIPYITKPSTQLPGPYCPIPCNCKVLSPSGLLIHCQERNIESLSDLRPPPQNPR 366
Query: 59 ELVLTGNNLTALPPGLLDALPALRTAHLGAN 89
+L+L GN + +L L L HLG N
Sbjct: 367 KLILAGNIIHSLMKSDLVEYFTLEMLHLGNN 397
>gi|27436867 slit and trk like 4 protein [Homo sapiens]
Length = 837
Score = 53.9 bits (128), Expect = 9e-08
Identities = 30/81 (37%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 58 TELVLTGNNLTALPP-GLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDL 116
T L + GN + LP G+L+ + + L NPW C C L+PL+AWL P +
Sbjct: 181 THLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLPLKAWLENMPYNIYIGEA 240
Query: 117 RCVAPPALRGRLLPYLAEDEL 137
C P L GRLL + EL
Sbjct: 241 ICETPSDLYGRLLKETNKQEL 261
Score = 43.9 bits (102), Expect = 1e-04
Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 1/63 (1%)
Query: 60 LVLTGNNLTALP-PGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRC 118
L L N LP G+LD L +L L NPW C C LV L+ W+ + ++L+C
Sbjct: 501 LNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWVEKLSDGIVVKELKC 560
Query: 119 VAP 121
P
Sbjct: 561 ETP 563
Score = 33.1 bits (74), Expect = 0.17
Identities = 20/74 (27%), Positives = 31/74 (41%), Gaps = 6/74 (8%)
Query: 22 PAAGCPAPCSC------AGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGLL 75
P CPAPC C G V+C + + S P++ +L + GN++ +
Sbjct: 338 PLTPCPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKDVDVSDF 397
Query: 76 DALPALRTAHLGAN 89
L HLG+N
Sbjct: 398 TDFEGLDLLHLGSN 411
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 53.5 bits (127), Expect = 1e-07
Identities = 27/71 (38%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Query: 19 PSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGLLDAL 78
PS CPA C+C+ +VDC +GLT +PT P TE+ L N + +PPG
Sbjct: 266 PSCSVLHCPAACTCSNNIVDCRGKGLT--EIPTNLPETITEIRLEQNTIKVIPPGAFSPY 323
Query: 79 PALRTAHLGAN 89
LR L N
Sbjct: 324 KKLRRIDLSNN 334
Score = 50.4 bits (119), Expect = 1e-06
Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 8 ALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNL 67
+LSL L+L CPA CSC+G+ VDC GL S+P P +T L L GNN+
Sbjct: 10 SLSLGLVLAILNKVAPQACPAQCSCSGSTVDC--HGLALRSVPRNIPRNTERLDLNGNNI 67
Query: 68 TALPPGLLDALPALRTAHLGAN 89
T + L LR L N
Sbjct: 68 TRITKTDFAGLRHLRVLQLMEN 89
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/71 (39%), Positives = 34/71 (47%), Gaps = 2/71 (2%)
Query: 56 DTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRD 115
D L L NN+T L + +P LRT L +N CDC L L WL RP Y
Sbjct: 176 DLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQRPRVGLY-- 233
Query: 116 LRCVAPPALRG 126
+C+ P LRG
Sbjct: 234 TQCMGPSHLRG 244
Score = 47.4 bits (111), Expect = 9e-06
Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Query: 22 PAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGL 74
P + CP C+C T+V C +GL LP P D TEL L GN T +P L
Sbjct: 723 PLSRCPTECTCLDTVVRCSNKGL--KVLPKGIPRDVTELYLDGNQFTLVPKEL 773
Score = 44.3 bits (103), Expect = 7e-05
Identities = 26/66 (39%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L N +T + PG D L +L T +L ANP+ C+C L L WL R +R + RC
Sbjct: 635 LSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWL--RKKRIVTGNPRCQ 692
Query: 120 APPALR 125
P L+
Sbjct: 693 KPYFLK 698
Score = 43.5 bits (101), Expect = 1e-04
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 3/65 (4%)
Query: 26 CPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTAL-PPGLLDALPALRTA 84
CP C C GT VDC + L +P P T EL L N T L G+ LP LR
Sbjct: 506 CPEKCRCEGTTVDCSNQKLN--KIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKI 563
Query: 85 HLGAN 89
+ N
Sbjct: 564 NFSNN 568
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRD---L 116
L L GN+++ +P G + L AL +GANP CDC + L W+ ++ Y++
Sbjct: 830 LSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWV-----KSEYKEPGIA 884
Query: 117 RCVAPPALRGRLL 129
RC P + +LL
Sbjct: 885 RCAGPGEMADKLL 897
Score = 40.0 bits (92), Expect = 0.001
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L N L + G L A++T HL NP+ CDC L L +L P RC
Sbjct: 401 LSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLHTNPIET--SGARCT 458
Query: 120 APPALRGRLLPYLAEDELRAA 140
+P L + + + + R +
Sbjct: 459 SPRRLANKRIGQIKSKKFRCS 479
>gi|40217817 slit and trk like 1 protein [Homo sapiens]
Length = 696
Score = 53.5 bits (127), Expect = 1e-07
Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 55 VDTTELVLTGNNLTALP-PGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPY 113
V T L L GN L LP +L+ +P + L NPW C C L+ L+ WL P+ A
Sbjct: 177 VPITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLSLKEWLENIPKNALI 236
Query: 114 RDLRCVAPPALRGRLLPYLAEDEL 137
+ C AP L+G+ L E +L
Sbjct: 237 GRVVCEAPTRLQGKDLNETTEQDL 260
Score = 46.6 bits (109), Expect = 1e-05
Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 1/84 (1%)
Query: 55 VDTTELVLTGNNLTALP-PGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPY 113
V ++L L N LP G+LD L ++ L NPW C C +VP + W
Sbjct: 494 VSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWECSCTIVPFKQWAERLGSEVLM 553
Query: 114 RDLRCVAPPALRGRLLPYLAEDEL 137
DL+C P + L+ DE+
Sbjct: 554 SDLKCETPVNFFRKDFMLLSNDEI 577
>gi|52353306 leucine rich repeat containing 55 [Homo sapiens]
Length = 341
Score = 53.1 bits (126), Expect = 2e-07
Identities = 33/88 (37%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 5 PRGALSLLLLLLAPP---SRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELV 61
P A+ L+ LLLA S CP C+C +VDC + L S+P P+DT L
Sbjct: 57 PHPAMLLISLLLAAGLMHSDAGTSCPVLCTCRNQVVDCSSQRLF--SVPPDLPMDTRNLS 114
Query: 62 LTGNNLTALPPGLLDALPALRTAHLGAN 89
L N +TA+PPG L L+ L N
Sbjct: 115 LAHNRITAVPPGYLTCYMELQVLDLHNN 142
Score = 52.4 bits (124), Expect = 3e-07
Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 50 PTAFP--VDTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGR 107
P AF + +L L+ L L L+ LP L T +G NPW C C + PL WL R
Sbjct: 198 PQAFQGLMQLRDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNR 257
Query: 108 PER--APYRDLRCVAPPALRGRLLPYLAEDELRA 139
+R A + C PP + G L L E+ +A
Sbjct: 258 IQRCTADSQLAECRGPPEVEGAPLFSLTEESFKA 291
>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
Length = 958
Score = 52.4 bits (124), Expect = 3e-07
Identities = 32/84 (38%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 55 VDTTELVLTGNNLTALP-PGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPY 113
V T L L GN L LP GLL + + L NPW C C L+ L+ WL A
Sbjct: 200 VPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALV 259
Query: 114 RDLRCVAPPALRGRLLPYLAEDEL 137
D+ C P L GR L +++ EL
Sbjct: 260 GDVVCETPFRLHGRDLDEVSKQEL 283
Score = 39.7 bits (91), Expect = 0.002
Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Query: 60 LVLTGNNLTALP-PGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRC 118
L L N+ T+LP G+LD L +L L NPW C C +V ++ W+ ++ C
Sbjct: 533 LNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNPWDCTCDIVGMKLWVEQLKVGVLVDEVIC 592
Query: 119 VAP 121
AP
Sbjct: 593 KAP 595
Score = 27.3 bits (59), Expect = 9.4
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 8/70 (11%)
Query: 26 CPAPCSCA---GTL-VDCGRRGLTWAS--LPTAFPVDTTELVLTGNNLTALPPGLLDALP 79
C C C G L V C RG+ S P FP+ L+L+GN L L P
Sbjct: 48 CDNACPCEEKDGILTVSCENRGIISLSEISPPRFPI--YHLLLSGNLLNRLYPNEFVNYT 105
Query: 80 ALRTAHLGAN 89
HLG+N
Sbjct: 106 GASILHLGSN 115
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 52.0 bits (123), Expect = 4e-07
Identities = 28/77 (36%), Positives = 37/77 (48%)
Query: 59 ELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRC 118
E+ L NNLT LP L L L HL NPW C+C ++ L W+ RC
Sbjct: 271 EINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIKDMAPSNTACCARC 330
Query: 119 VAPPALRGRLLPYLAED 135
PP L+GR + L ++
Sbjct: 331 NTPPNLKGRYIGELDQN 347
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 51.6 bits (122), Expect = 5e-07
Identities = 28/71 (39%), Positives = 35/71 (49%)
Query: 59 ELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRC 118
EL L+ NNL +LP L L L HL NPW C+C ++ L WL RC
Sbjct: 281 ELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWLKETVPSNTTCCARC 340
Query: 119 VAPPALRGRLL 129
AP L+GR +
Sbjct: 341 HAPAGLKGRYI 351
Score = 40.8 bits (94), Expect = 8e-04
Identities = 35/106 (33%), Positives = 43/106 (40%), Gaps = 22/106 (20%)
Query: 3 SGPRGALSLLLLLLAPP-----------------SRPAAGCPAPCSCA--GTLVDCGRRG 43
S P GAL L L L +PP S PA CP CSC+ + V C RR
Sbjct: 18 SWPHGAL-LFLWLFSPPLGAGGGGVAVTSAAGGGSPPATSCPVACSCSNQASRVICTRRD 76
Query: 44 LTWASLPTAFPVDTTELVLTGNNLTALPPGLLDALPALRTAHLGAN 89
L A +P + PV+T L L N + + L L L N
Sbjct: 77 L--AEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKN 120
>gi|239752702 PREDICTED: leucine rich repeat containing 38, partial
[Homo sapiens]
Length = 254
Score = 51.2 bits (121), Expect = 6e-07
Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAP--YRDLR 117
L L NNL +L L ALPALR+ L NPW CDC L +W+ + P +++
Sbjct: 117 LELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQ 176
Query: 118 CVAPPALRGRLLPYLAE---DELRAACAPGPLC 147
C P R L L+E E R + + LC
Sbjct: 177 CSLPMESRRISLRELSEASFSECRFSLSLTDLC 209
Score = 31.2 bits (69), Expect = 0.65
Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 2/34 (5%)
Query: 38 DCGRRGLTWASLPTAFPVDTTELVLTGNNLTALP 71
DC RGL S+P FP+D +L++ GN + +P
Sbjct: 1 DCRDRGLP--SVPDPFPLDVRKLLVAGNRIQRIP 32
>gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo
sapiens]
Length = 408
Score = 51.2 bits (121), Expect = 6e-07
Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAP--YRDLR 117
L L NNL +L L ALPALR+ L NPW CDC L +W+ + P +++
Sbjct: 271 LELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQ 330
Query: 118 CVAPPALRGRLLPYLAE---DELRAACAPGPLC 147
C P R L L+E E R + + LC
Sbjct: 331 CSLPMESRRISLRELSEASFSECRFSLSLTDLC 363
Score = 28.9 bits (63), Expect = 3.2
Identities = 13/31 (41%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
Query: 41 RRGLTWASLPTAFPVDTTELVLTGNNLTALP 71
RRGL S+P FP+D +L++ GN + +P
Sbjct: 158 RRGLP--SVPDPFPLDVRKLLVAGNRIQRIP 186
>gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo
sapiens]
Length = 408
Score = 51.2 bits (121), Expect = 6e-07
Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAP--YRDLR 117
L L NNL +L L ALPALR+ L NPW CDC L +W+ + P +++
Sbjct: 271 LELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQ 330
Query: 118 CVAPPALRGRLLPYLAE---DELRAACAPGPLC 147
C P R L L+E E R + + LC
Sbjct: 331 CSLPMESRRISLRELSEASFSECRFSLSLTDLC 363
Score = 28.9 bits (63), Expect = 3.2
Identities = 13/31 (41%), Positives = 20/31 (64%), Gaps = 2/31 (6%)
Query: 41 RRGLTWASLPTAFPVDTTELVLTGNNLTALP 71
RRGL S+P FP+D +L++ GN + +P
Sbjct: 158 RRGLP--SVPDPFPLDVRKLLVAGNRIQRIP 186
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 50.8 bits (120), Expect = 8e-07
Identities = 33/87 (37%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
Query: 3 SGPRGALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVL 62
+GP LLL A A+ CPA C+C GT VDC GL ++P P +T L L
Sbjct: 11 AGPVRPELWLLLWAAAWRLGASACPALCTCTGTTVDCHGTGL--QAIPKNIPRNTERLEL 68
Query: 63 TGNNLTALPPGLLDALPALRTAHLGAN 89
GNN+T + L LR L N
Sbjct: 69 NGNNITRIHKNDFAGLKQLRVLQLMEN 95
Score = 49.7 bits (117), Expect = 2e-06
Identities = 33/95 (34%), Positives = 44/95 (46%), Gaps = 9/95 (9%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L N +T + PG D L +L T +L ANP+ C+C+L L WL R + + RC
Sbjct: 642 LSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWL--RKRKIVTGNPRCQ 699
Query: 120 APPALRGRLLPYLA-------EDELRAACAPGPLC 147
P LR L +A E + C P P C
Sbjct: 700 NPDFLRQIPLQDVAFPDFRCEEGQEEGGCLPRPQC 734
Score = 48.9 bits (115), Expect = 3e-06
Identities = 26/67 (38%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L NN+T +P + +P LRT L +N CDC L L WL RP + +C
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGLF--TQCS 243
Query: 120 APPALRG 126
P +LRG
Sbjct: 244 GPASLRG 250
Score = 48.9 bits (115), Expect = 3e-06
Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 2/67 (2%)
Query: 23 AAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGLLDALPALR 82
+ CPA C+C+ +VDC +GLT ++P P TE+ L N + ++PPG LR
Sbjct: 279 SGSCPAMCTCSNGIVDCRGKGLT--AIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLR 336
Query: 83 TAHLGAN 89
L N
Sbjct: 337 RIDLSNN 343
Score = 44.7 bits (104), Expect = 6e-05
Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 22 PAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGLLDALPAL 81
P CP C+C T+V C + L +LP P + TEL L GN T L PG L L
Sbjct: 730 PRPQCPQECACLDTVVRCSNKHLR--ALPKGIPKNVTELYLDGNQFT-LVPGQLSTFKYL 786
Query: 82 RTAHLGAN 89
+ L N
Sbjct: 787 QLVDLSNN 794
Score = 42.7 bits (99), Expect = 2e-04
Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRD---L 116
L L GN+++ L G+ + +L +GANP CDC L L +W+ + Y++
Sbjct: 837 LSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWV-----KTGYKEPGIA 891
Query: 117 RCVAPPALRGRLL 129
RC P + G+LL
Sbjct: 892 RCAGPQDMEGKLL 904
Score = 40.8 bits (94), Expect = 8e-04
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Query: 60 LVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCV 119
L L N + +L G +L A++T HL NP+ CDC L L +L P RC
Sbjct: 410 LSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLRTNPIET--SGARCA 467
Query: 120 APPALRGRLLPYLAEDELRAA 140
+P L + + + + R +
Sbjct: 468 SPRRLANKRIGQIKSKKFRCS 488
Score = 35.8 bits (81), Expect = 0.026
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 3/65 (4%)
Query: 26 CPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTAL-PPGLLDALPALRTA 84
CP C C +V+C LT +P P T EL L N ++ L G+ L L+
Sbjct: 513 CPHKCRCEANVVECSSLKLT--KIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKI 570
Query: 85 HLGAN 89
+L N
Sbjct: 571 NLSNN 575
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.141 0.458
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,188,663
Number of Sequences: 37866
Number of extensions: 458376
Number of successful extensions: 2757
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 2305
Number of HSP's gapped (non-prelim): 452
length of query: 206
length of database: 18,247,518
effective HSP length: 97
effective length of query: 109
effective length of database: 14,574,516
effective search space: 1588622244
effective search space used: 1588622244
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.