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Search of human proteins with 4504059
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504059 gonadotropin-releasing hormone receptor isoform 1
[Homo sapiens]
(328 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Ho... 671 0.0
gi|61676184 gonadotropin-releasing hormone receptor isoform 2 [H... 343 9e-95
gi|4502331 arginine vasopressin receptor 1A [Homo sapiens] 134 1e-31
gi|32307152 oxytocin receptor [Homo sapiens] 120 1e-27
gi|4502333 arginine vasopressin receptor 1B [Homo sapiens] 119 3e-27
gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens] 101 1e-21
gi|4503905 galanin receptor 2 [Homo sapiens] 100 2e-21
gi|46395496 G protein-coupled receptor for asthma susceptibility... 97 3e-20
gi|46391085 G protein-coupled receptor for asthma susceptibility... 97 3e-20
gi|4502455 bombesin-like receptor 3 [Homo sapiens] 94 1e-19
gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo sap... 92 8e-19
gi|21426829 prokineticin receptor 2 [Homo sapiens] 89 5e-18
gi|4885057 apelin receptor [Homo sapiens] 88 9e-18
gi|20373179 G protein-coupled receptor 73 [Homo sapiens] 87 2e-17
gi|167000885 galanin receptor 1 [Homo sapiens] 84 2e-16
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 82 7e-16
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 82 7e-16
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 82 7e-16
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 82 9e-16
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec... 82 9e-16
gi|4503907 galanin receptor 3 [Homo sapiens] 81 1e-15
gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 81 1e-15
gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens] 81 1e-15
gi|5453666 G protein-coupled receptor 19 [Homo sapiens] 80 3e-15
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 80 3e-15
gi|161484640 neuromedin B receptor [Homo sapiens] 80 3e-15
gi|21264324 trace amine associated receptor 1 [Homo sapiens] 78 1e-14
gi|223718066 opioid receptor, mu 1 isoform MOR-1G2 [Homo sapiens] 77 2e-14
gi|222080109 orexin receptor 2 [Homo sapiens] 76 4e-14
gi|222080095 orexin receptor 1 [Homo sapiens] 76 5e-14
>gi|4504059 gonadotropin-releasing hormone receptor isoform 1 [Homo
sapiens]
Length = 328
Score = 671 bits (1732), Expect = 0.0
Identities = 328/328 (100%), Positives = 328/328 (100%)
Query: 1 MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL 60
MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL
Sbjct: 1 MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL 60
Query: 61 QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL 120
QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
Sbjct: 61 QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL 120
Query: 121 KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRM 180
KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRM
Sbjct: 121 KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRM 180
Query: 181 IHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTR 240
IHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTR
Sbjct: 181 IHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTR 240
Query: 241 VLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRL 300
VLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRL
Sbjct: 241 VLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRL 300
Query: 301 SDPVNHFFFLFAFLNPCFDPLIYGYFSL 328
SDPVNHFFFLFAFLNPCFDPLIYGYFSL
Sbjct: 301 SDPVNHFFFLFAFLNPCFDPLIYGYFSL 328
>gi|61676184 gonadotropin-releasing hormone receptor isoform 2 [Homo
sapiens]
Length = 249
Score = 343 bits (881), Expect = 9e-95
Identities = 175/175 (100%), Positives = 175/175 (100%)
Query: 1 MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL 60
MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL
Sbjct: 1 MANSASPEQNQNHCSAINNSIPLMQGNLPTLTLSGKIRVTVTFFLFLLSATFNASFLLKL 60
Query: 61 QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL 120
QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL
Sbjct: 61 QKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYL 120
Query: 121 KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQL 175
KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQL
Sbjct: 121 KLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQL 175
>gi|4502331 arginine vasopressin receptor 1A [Homo sapiens]
Length = 418
Score = 134 bits (337), Expect = 1e-31
Identities = 85/313 (27%), Positives = 153/313 (48%), Gaps = 33/313 (10%)
Query: 36 KIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVM 95
K+ + V F ++ N+S LL L + +K SRM L ++HL+LA+L +
Sbjct: 52 KLEIAVLAVTFAVAVLGNSSVLLALHRTP------RKTSRMHLFIRHLSLADLAVAFFQV 105
Query: 96 PLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPL-ALKSNSK 154
W+IT ++ + LC+V+ +L++F M+A A+M+VV++ DR +A+ PL L+ ++
Sbjct: 106 LPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPAR 165
Query: 155 VGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFF 214
+ M+ AW+LS V + PQ ++F MI + + + ++ +F Q W Y +
Sbjct: 166 RSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWA------TFIQPWGSRAYVTW 219
Query: 215 TFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLN-------------------QSK 255
+F+ P+ I+ C I + + + Q S
Sbjct: 220 MTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSV 279
Query: 256 NNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDP-EMLNRLSDPVNHFFFLFAFL 314
+I RA+++T+KMT T++ VCW P++++ +W +DP + +P L L
Sbjct: 280 KSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSL 339
Query: 315 NPCFDPLIYGYFS 327
N C +P IY +FS
Sbjct: 340 NSCCNPWIYMFFS 352
>gi|32307152 oxytocin receptor [Homo sapiens]
Length = 389
Score = 120 bits (302), Expect = 1e-27
Identities = 86/311 (27%), Positives = 150/311 (48%), Gaps = 36/311 (11%)
Query: 36 KIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVM 95
++ V V + LL+ + NA LL L+ QK SR+ +KHL++A+L+ + +
Sbjct: 40 RVEVAVLCLILLLALSGNACVLLALRTTRQKH------SRLFFFMKHLSIADLVVAVFQV 93
Query: 96 PLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKV 155
+W+IT ++Y +LLC+++ YL++ M+A ++++++SLDR LAI +PL +
Sbjct: 94 LPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLR-SLRRRT 152
Query: 156 GQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFT 215
+ V W+ V + PQ++IF + +AD VF F Q W Y +
Sbjct: 153 DRLAVLATWLGCLVASAPQVHIFSLREVADG-----VFD---CWAVFIQPWGPKAYITWI 204
Query: 216 FSCLFIIPLFIMLICNAKIIFTLTRVLH---------QDPH----------ELQLNQSKN 256
++I+P+ ++ C I F + + L + P L S
Sbjct: 205 TLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVK 264
Query: 257 NIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNP 316
I +A+++T+KMT +F VCWTP++ + +W +D S + L A LN
Sbjct: 265 LISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFI--IVMLLASLNS 322
Query: 317 CFDPLIYGYFS 327
C +P IY F+
Sbjct: 323 CCNPWIYMLFT 333
>gi|4502333 arginine vasopressin receptor 1B [Homo sapiens]
Length = 424
Score = 119 bits (299), Expect = 3e-27
Identities = 86/324 (26%), Positives = 152/324 (46%), Gaps = 48/324 (14%)
Query: 36 KIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVM 95
K+ + V + +L+ N + LL L + G+K SRM L + HL L +L L +
Sbjct: 35 KVEIGVLATVLVLATGGNLAVLLTLG------QLGRKRSRMHLFVLHLALTDLAVALFQV 88
Query: 96 PLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSNSKV 155
+W+IT ++ +LLC+ + YL++ SM+A +M++ ++LDR LA+ P L+S +
Sbjct: 89 LPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHP--LRSLQQP 146
Query: 156 GQS---MVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYN 212
GQS ++ W+L+++F+ PQ++IF + + SG ++ F W Y
Sbjct: 147 GQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWA------DFGFPWGPRAYL 200
Query: 213 FFTFSCLFIIPLFIMLICNAKIIFTLTRVL------------------HQDPHELQLN-- 252
+T +F++P+ ++ C + I + + L P L
Sbjct: 201 TWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTR 260
Query: 253 ------QSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNH 306
S N I RA+++T+KMT ++ CW P++ + +W +D + D N
Sbjct: 261 GLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPD--EDSTNV 318
Query: 307 FF---FLFAFLNPCFDPLIYGYFS 327
F L LN C +P IY F+
Sbjct: 319 AFTISMLLGNLNSCCNPWIYMGFN 342
>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
Length = 371
Score = 101 bits (251), Expect = 1e-21
Identities = 81/298 (27%), Positives = 137/298 (45%), Gaps = 24/298 (8%)
Query: 45 LFLLSATFNASFL---LKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMW 101
L LLS F A L L L ++ +G + + + + HL LA+L L + W
Sbjct: 41 LALLSIVFVAVALSNGLVLAALARRGRRGH-WAPIHVFIGHLCLADLAVALFQVLPQLAW 99
Query: 102 NITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRP-LALKSNSKVGQSM- 159
T ++ + LC+ + YL++ MYA ++M++ ++LDR AI RP LA + S +
Sbjct: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
Query: 160 VGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCL 219
V +AW S + + PQL+IF ++ SG T ++ F++ W + Y + +
Sbjct: 160 VLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWA------CFAEPWGRRTYVTWIALMV 213
Query: 220 FIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKN----------NIPRARLKTLKMT 269
F+ P + C I + L P E + + ++ A KT++MT
Sbjct: 214 FVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
Query: 270 VAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFS 327
+ + +CW P++++ +W +DPE L L A LN C +P IY FS
Sbjct: 274 LVIVVVYVLCWAPFFLVQLWAAWDPEA--PLEGAPFVLLMLLASLNSCTNPWIYASFS 329
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 100 bits (249), Expect = 2e-21
Identities = 71/260 (27%), Positives = 124/260 (47%), Gaps = 19/260 (7%)
Query: 70 GKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPA 129
G+ +S L + +L +A+L L +P W G LLCK + +L +M+A +
Sbjct: 54 GQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASS 113
Query: 130 FMMVVISLDRSLAITRPLALKS--NSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSS 187
F + +SLDR LAI PL + + + +GL W LS +F+GP L +R LA+ +
Sbjct: 114 FTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLT 173
Query: 188 GQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPH 247
V H ++S +A + TF +++P+ ++ + A+ + L R + DP
Sbjct: 174 ---------VCHPAWSAPRRRAM-DICTFVFSYLLPVLVLGLTYARTLRYLWRAV--DP- 220
Query: 248 ELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHF 307
+ + RA+ K +M + A F +CW P++ L + WF L R + +
Sbjct: 221 ----VAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRIL 276
Query: 308 FFLFAFLNPCFDPLIYGYFS 327
L ++ N C +P++Y S
Sbjct: 277 SHLVSYANSCVNPIVYALVS 296
>gi|46395496 G protein-coupled receptor for asthma susceptibility
isoform A [Homo sapiens]
Length = 371
Score = 96.7 bits (239), Expect = 3e-20
Identities = 73/270 (27%), Positives = 125/270 (46%), Gaps = 26/270 (9%)
Query: 71 KKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAF 130
KK SRM + L + + L+ + D W T + A +L+C+V+ YL++ +YA +
Sbjct: 78 KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTY 137
Query: 131 MMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQT 190
++V +S+DR AI P+ K + ++ +AW LS +F+ P L IF L S+G+
Sbjct: 138 VLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTL--SNGEV 195
Query: 191 KVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTL--------TRVL 242
QC +W Y ++ IPL I+ I +I T+ T +
Sbjct: 196 ----QCWALWPDDSYWTP--YMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVIS 249
Query: 243 HQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSD 302
+ +L + ++ I +A++K +K ++ +F CW+PY++ I + N L D
Sbjct: 250 NCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDIL-----DNFNLLPD 304
Query: 303 PVNHFFFLFAF-----LNPCFDPLIYGYFS 327
F+ LN +PLIY FS
Sbjct: 305 TQERFYASVIIQNLPALNSAINPLIYCVFS 334
>gi|46391085 G protein-coupled receptor for asthma susceptibility
isoform B [Homo sapiens]
Length = 377
Score = 96.7 bits (239), Expect = 3e-20
Identities = 73/270 (27%), Positives = 125/270 (46%), Gaps = 26/270 (9%)
Query: 71 KKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAF 130
KK SRM + L + + L+ + D W T + A +L+C+V+ YL++ +YA +
Sbjct: 78 KKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLVCRVVRYLQVVLLYASTY 137
Query: 131 MMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQT 190
++V +S+DR AI P+ K + ++ +AW LS +F+ P L IF L S+G+
Sbjct: 138 VLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIPTLIIFGKRTL--SNGEV 195
Query: 191 KVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTL--------TRVL 242
QC +W Y ++ IPL I+ I +I T+ T +
Sbjct: 196 ----QCWALWPDDSYWTP--YMTIVAFLVYFIPLTIISIMYGIVIRTIWIKSKTYETVIS 249
Query: 243 HQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSD 302
+ +L + ++ I +A++K +K ++ +F CW+PY++ I + N L D
Sbjct: 250 NCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDIL-----DNFNLLPD 304
Query: 303 PVNHFFFLFAF-----LNPCFDPLIYGYFS 327
F+ LN +PLIY FS
Sbjct: 305 TQERFYASVIIQNLPALNSAINPLIYCVFS 334
>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
Length = 399
Score = 94.4 bits (233), Expect = 1e-19
Identities = 69/258 (26%), Positives = 123/258 (47%), Gaps = 15/258 (5%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
+ + L +LL L +P+D + W G + CKVLS+++L S+ F + ++S
Sbjct: 84 IFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSA 143
Query: 138 DRSLAITRPLALKSNSKVGQSMV--GLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQ 195
DR A+ +PL + ++ + ++ V G WI+S +FA P+ IF ++ + F
Sbjct: 144 DRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEA-IFSNVYTFRDPNKNMTFES 202
Query: 196 CVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSK 255
C ++ S+ Q ++ F +IIPL I+ + + I TL + P E Q + K
Sbjct: 203 CTSY-PVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARK 261
Query: 256 NNIPRARL-KTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFF----- 309
R R+ +T+ + VA F +CW P ++L +++ F + + HF F
Sbjct: 262 QIESRKRIARTVLVLVAL---FALCWLPNHLLYLYHSFTSQ--TYVDPSAMHFIFTIFSR 316
Query: 310 LFAFLNPCFDPLIYGYFS 327
+ AF N C +P + S
Sbjct: 317 VLAFSNSCVNPFALYWLS 334
>gi|225903385 arginine vasopressin receptor 2 isoform 2 [Homo
sapiens]
Length = 309
Score = 91.7 bits (226), Expect = 8e-19
Identities = 70/266 (26%), Positives = 125/266 (46%), Gaps = 22/266 (8%)
Query: 45 LFLLSATFNASFL---LKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMW 101
L LLS F A L L L ++ +G + + + + HL LA+L L + W
Sbjct: 41 LALLSIVFVAVALSNGLVLAALARRGRRGH-WAPIHVFIGHLCLADLAVALFQVLPQLAW 99
Query: 102 NITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRP-LALKSNSKVGQSM- 159
T ++ + LC+ + YL++ MYA ++M++ ++LDR AI RP LA + S +
Sbjct: 100 KATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRP 159
Query: 160 VGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCL 219
V +AW S + + PQL+IF ++ SG T ++ F++ W + Y + +
Sbjct: 160 VLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWA------CFAEPWGRRTYVTWIALMV 213
Query: 220 FIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKN----------NIPRARLKTLKMT 269
F+ P + C I + L P E + + ++ A KT++MT
Sbjct: 214 FVAPTLGIAACQVLIFREIHASLVPGPSERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMT 273
Query: 270 VAFATSFTVCWTPYYVLGIWYWFDPE 295
+ + +CW P++++ +W +DPE
Sbjct: 274 LVIVVVYVLCWAPFFLVQLWAAWDPE 299
>gi|21426829 prokineticin receptor 2 [Homo sapiens]
Length = 384
Score = 89.0 bits (219), Expect = 5e-18
Identities = 59/217 (27%), Positives = 102/217 (47%), Gaps = 9/217 (4%)
Query: 71 KKLSRM-KLLLKHLTLANLLETLIVMPLDGMWNITVQ--WYAGELLCKVLSYLKLFSMYA 127
KKL + LL+ +L +++ L +I P + + + Q W G +LC ++YL+ S+Y
Sbjct: 82 KKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYV 141
Query: 128 PAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSS 187
++ I++DR LAI PL + N + ++ L W++S + A P Y L
Sbjct: 142 STNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAIPSAYFATETVLFIVK 201
Query: 188 GQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPH 247
Q K+F C Q + Y F F F+ P+ M +C A+I + +
Sbjct: 202 SQEKIF--CGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMTLCYARI---SRELWFKAVP 256
Query: 248 ELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYY 284
Q Q + + R R KT+ + + T++ +CW P+Y
Sbjct: 257 GFQTEQIRKRL-RCRRKTVLVLMCILTAYVLCWAPFY 292
>gi|4885057 apelin receptor [Homo sapiens]
Length = 380
Score = 88.2 bits (217), Expect = 9e-18
Identities = 81/314 (25%), Positives = 135/314 (42%), Gaps = 49/314 (15%)
Query: 34 SGKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLI 93
SG + + +FLL T N L WT + +K + + L +A+L ++
Sbjct: 27 SGALIPAIYMLVFLLGTTGNGLVL-----WTVFRSSREKRRSADIFIASLAVADLT-FVV 80
Query: 94 VMPLDGMWNIT-VQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKSN 152
+PL + W G CK+ SYL +MYA F + +S DR LAI RP+A N
Sbjct: 81 TLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVA---N 137
Query: 153 SKV-----GQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSF----- 202
+++ G + W+L+++ A P + + D TKV QC S
Sbjct: 138 ARLRLRVSGAVATAVLWVLAALLAMP---VMVLRTTGDLENTTKV--QCYMDYSMVATVS 192
Query: 203 SQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRAR 262
S+W + + + F++P IML C I T+ ++ E R R
Sbjct: 193 SEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL---------RKR 243
Query: 263 LKTLKMTVAFATSFTVCWTPY------YVLG-IWYW---FDPEMLNRLSDPVNHFFFLFA 312
+ L + V +F +CW PY Y+LG + +W FD ++N + + +
Sbjct: 244 RRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMN-----IFPYCTCIS 298
Query: 313 FLNPCFDPLIYGYF 326
++N C +P +Y +F
Sbjct: 299 YVNSCLNPFLYAFF 312
>gi|20373179 G protein-coupled receptor 73 [Homo sapiens]
Length = 393
Score = 87.4 bits (215), Expect = 2e-17
Identities = 61/243 (25%), Positives = 109/243 (44%), Gaps = 9/243 (3%)
Query: 71 KKLSRM-KLLLKHLTLANLLETLIVMPLDGMWNITVQ--WYAGELLCKVLSYLKLFSMYA 127
KKL + LL+ +L +++ L ++ P + + + Q W G +LC ++YL+ S+Y
Sbjct: 91 KKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYV 150
Query: 128 PAFMMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSS 187
++ I++DR LAI PL + + ++ L W +S + A P Y L
Sbjct: 151 STNALLAIAIDRYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIPSAYFTTETVLVIVK 210
Query: 188 GQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPH 247
Q K+F C Q + Y F F F+ P+ M +C A+I + +
Sbjct: 211 SQEKIF--CGQIWPVDQQLYYKSYFLFIFGIEFVGPVVTMTLCYARI---SRELWFKAVP 265
Query: 248 ELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHF 307
Q Q + + R R KT+ + + T++ +CW P+Y I F P + + + F
Sbjct: 266 GFQTEQIRKRL-RCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAF 324
Query: 308 FFL 310
+ +
Sbjct: 325 YIV 327
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 84.0 bits (206), Expect = 2e-16
Identities = 67/267 (25%), Positives = 113/267 (42%), Gaps = 24/267 (8%)
Query: 66 KKEKGKKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSM 125
+ + GK S L + +L++A+L L +P W G +CK + Y SM
Sbjct: 60 RSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSM 119
Query: 126 YAPAFMMVVISLDRSLAI-----TRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRM 180
F + +S+DR +AI + L + N+ +G VG W LS A P Y +
Sbjct: 120 LVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLG---VGCIWALSIAMASPVAYHQGL 176
Query: 181 IHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTR 240
H +S QT + Q + H+ Y TF +++PL ++ C AK++ L
Sbjct: 177 FH-PRASNQTFCWEQ------WPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHL-- 227
Query: 241 VLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRL 300
H+ N SK + ++ KT + + F + W P++++ +W F L
Sbjct: 228 ------HKKLKNMSKKS-EASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPA 280
Query: 301 SDPVNHFFFLFAFLNPCFDPLIYGYFS 327
S A+ N +P+IY + S
Sbjct: 281 SFLFRITAHCLAYSNSSVNPIIYAFLS 307
>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
Length = 420
Score = 82.0 bits (201), Expect = 7e-16
Identities = 64/261 (24%), Positives = 122/261 (46%), Gaps = 16/261 (6%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + +L +++LL + MP+ + NI W G +CK+ ++ S+ A F +V I++
Sbjct: 82 LFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAV 141
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSS-GQTKVFSQC 196
DR + P K K ++ + W+L+ P M+H+ + + ++ SQ
Sbjct: 142 DRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAV---MLHVQEEKYYRVRLNSQN 198
Query: 197 VTHCSF---SQWWHQAFYNFFT---FSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQ 250
T + W +Q +T F+ +++ PL +++I +I +L R PH +
Sbjct: 199 KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRA--AVPHTGR 256
Query: 251 LNQSK-NNIPRARLKTLKMTVAFATSFTVCWTPYY---VLGIWYWFDPEMLNRLSDPVNH 306
NQ + + + R + K +KM + A F + W P + +L + P L ++ +
Sbjct: 257 KNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYP 316
Query: 307 FFFLFAFLNPCFDPLIYGYFS 327
F AF N +P+IYG+F+
Sbjct: 317 FAHWLAFGNSSVNPIIYGFFN 337
>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
Length = 522
Score = 82.0 bits (201), Expect = 7e-16
Identities = 64/261 (24%), Positives = 122/261 (46%), Gaps = 16/261 (6%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + +L +++LL + MP+ + NI W G +CK+ ++ S+ A F +V I++
Sbjct: 184 LFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAV 243
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSS-GQTKVFSQC 196
DR + P K K ++ + W+L+ P M+H+ + + ++ SQ
Sbjct: 244 DRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAV---MLHVQEEKYYRVRLNSQN 300
Query: 197 VTHCSF---SQWWHQAFYNFFT---FSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQ 250
T + W +Q +T F+ +++ PL +++I +I +L R PH +
Sbjct: 301 KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRA--AVPHTGR 358
Query: 251 LNQSK-NNIPRARLKTLKMTVAFATSFTVCWTPYY---VLGIWYWFDPEMLNRLSDPVNH 306
NQ + + + R + K +KM + A F + W P + +L + P L ++ +
Sbjct: 359 KNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYP 418
Query: 307 FFFLFAFLNPCFDPLIYGYFS 327
F AF N +P+IYG+F+
Sbjct: 419 FAHWLAFGNSSVNPIIYGFFN 439
>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
Length = 423
Score = 82.0 bits (201), Expect = 7e-16
Identities = 64/261 (24%), Positives = 122/261 (46%), Gaps = 16/261 (6%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + +L +++LL + MP+ + NI W G +CK+ ++ S+ A F +V I++
Sbjct: 85 LFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAV 144
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSS-GQTKVFSQC 196
DR + P K K ++ + W+L+ P M+H+ + + ++ SQ
Sbjct: 145 DRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAV---MLHVQEEKYYRVRLNSQN 201
Query: 197 VTHCSF---SQWWHQAFYNFFT---FSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQ 250
T + W +Q +T F+ +++ PL +++I +I +L R PH +
Sbjct: 202 KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRA--AVPHTGR 259
Query: 251 LNQSK-NNIPRARLKTLKMTVAFATSFTVCWTPYY---VLGIWYWFDPEMLNRLSDPVNH 306
NQ + + + R + K +KM + A F + W P + +L + P L ++ +
Sbjct: 260 KNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYP 319
Query: 307 FFFLFAFLNPCFDPLIYGYFS 327
F AF N +P+IYG+F+
Sbjct: 320 FAHWLAFGNSSVNPIIYGFFN 340
>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
Length = 384
Score = 81.6 bits (200), Expect = 9e-16
Identities = 62/250 (24%), Positives = 111/250 (44%), Gaps = 14/250 (5%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + L L +LL + P+D + +W G + CK++ +++L S+ F + +S
Sbjct: 77 LFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSA 136
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLA--WILSSVFAGPQLYIFRMIHLADSSGQTKVFSQ 195
DR AI RP+ ++++ + + + A WI+S + A P+ +F +H + F
Sbjct: 137 DRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEA-VFSDLHPFHEESTNQTFIS 195
Query: 196 CVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSK 255
C + S H ++ +F ++IPL I+ + I L + + P E ++ K
Sbjct: 196 CAPY-PHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKK 254
Query: 256 NNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFF-----L 310
R RL K + F F CW P +V+ Y + + + + HF L
Sbjct: 255 QIESRKRL--AKTVLVFVGLFAFCWLPNHVI---YLYRSYHYSEVDTSMLHFVTSICARL 309
Query: 311 FAFLNPCFDP 320
AF N C +P
Sbjct: 310 LAFTNSCVNP 319
>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
receptor [Homo sapiens]
Length = 368
Score = 81.6 bits (200), Expect = 9e-16
Identities = 62/250 (24%), Positives = 111/250 (44%), Gaps = 14/250 (5%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
L + L L +LL + P+D + +W G + CK++ +++L S+ F + +S
Sbjct: 61 LFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSA 120
Query: 138 DRSLAITRPLALKSNSKVGQSMVGLA--WILSSVFAGPQLYIFRMIHLADSSGQTKVFSQ 195
DR AI RP+ ++++ + + + A WI+S + A P+ +F +H + F
Sbjct: 121 DRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEA-VFSDLHPFHEESTNQTFIS 179
Query: 196 CVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSK 255
C + S H ++ +F ++IPL I+ + I L + + P E ++ K
Sbjct: 180 CAPY-PHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKK 238
Query: 256 NNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFF-----L 310
R RL K + F F CW P +V+ Y + + + + HF L
Sbjct: 239 QIESRKRL--AKTVLVFVGLFAFCWLPNHVI---YLYRSYHYSEVDTSMLHFVTSICARL 293
Query: 311 FAFLNPCFDP 320
AF N C +P
Sbjct: 294 LAFTNSCVNP 303
>gi|4503907 galanin receptor 3 [Homo sapiens]
Length = 368
Score = 81.3 bits (199), Expect = 1e-15
Identities = 65/298 (21%), Positives = 124/298 (41%), Gaps = 23/298 (7%)
Query: 35 GKIRVTVTFFLFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKHLTLANLLETLIV 94
G + V V F L L T +L + + S L + +L +A+L L
Sbjct: 16 GAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCC 75
Query: 95 MPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPLALKS--N 152
+P W G L+CK + L +MYA +F + +S+DR LA+ PL ++
Sbjct: 76 VPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRT 135
Query: 153 SKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQA--- 209
+ ++ VGL W+L+++F+ P L + + CV W A
Sbjct: 136 PRNARAAVGLVWLLAALFSAPYLSYYGTVRYG-------ALELCVPA------WEDARRR 182
Query: 210 FYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLKTLKMT 269
+ TF+ +++P+ ++ + + + L + P +++ RA + +
Sbjct: 183 ALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAV--GPAGAAAAEARR---RATGRAGRAM 237
Query: 270 VAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGYFS 327
+A A + +CW P++ L + +W+ + + A+ N C +PL+Y S
Sbjct: 238 LAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALAS 295
>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
Length = 431
Score = 81.3 bits (199), Expect = 1e-15
Identities = 57/256 (22%), Positives = 113/256 (44%), Gaps = 17/256 (6%)
Query: 83 LTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLA 142
L L++LL T +P+ + NI+ W G +CK++ +++ ++ M I+++R
Sbjct: 87 LALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQG 146
Query: 143 ITRPLALK--SNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHC 200
+ P +K ++ +M+G+ W+++ + P M H+ + + C
Sbjct: 147 LVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSP------MWHVQQLEIKYDFLYEKEHIC 200
Query: 201 SFSQWW---HQAFYNFFTFSCLFIIPLFIMLICNAKIIFTL---TRVLHQDPHELQLNQS 254
+W HQ Y F LF++PL +MLI +KI + L RV +
Sbjct: 201 CLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKE 260
Query: 255 KNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGI---WYWFDPEMLNRLSDPVNHFFFLF 311
+ I R + + + M V F VCW P++V+ + + F+ E + + +
Sbjct: 261 MSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQII 320
Query: 312 AFLNPCFDPLIYGYFS 327
F N +P++Y + +
Sbjct: 321 GFSNSICNPIVYAFMN 336
>gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens]
Length = 375
Score = 80.9 bits (198), Expect = 1e-15
Identities = 65/269 (24%), Positives = 117/269 (43%), Gaps = 25/269 (9%)
Query: 71 KKLSRMKLLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAF 130
+K + LL+ +L ++ L L+ PL ++ I W GE LCK+ ++++ S+
Sbjct: 71 EKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSIL 130
Query: 131 MMVVISLDRSLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQL---YIFRMIHLADSS 187
+V+++L+R I P K + + L W+++ V + P L + + H S
Sbjct: 131 SLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNHSK 190
Query: 188 GQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLT---RVLHQ 244
+ + V S+ H+ Y F + +PL +L+C A+I L RV H+
Sbjct: 191 ALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRRLQRQGRVFHK 250
Query: 245 DPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPV 304
+ L+ K + + + M VAFA V W P +V + E + P+
Sbjct: 251 GTYSLRAGHMK----QVNVVLVVMVVAFA----VLWLPLHVFNSLEDWHHEAI-----PI 297
Query: 305 NHFFFLF------AFLNPCFDPLIYGYFS 327
H +F A + C +P IYG+ +
Sbjct: 298 CHGNLIFLVCHLLAMASTCVNPFIYGFLN 326
>gi|5453666 G protein-coupled receptor 19 [Homo sapiens]
Length = 415
Score = 79.7 bits (195), Expect = 3e-15
Identities = 59/270 (21%), Positives = 117/270 (43%), Gaps = 27/270 (10%)
Query: 25 QGNLPTLTLSGKIRVTVTFF--LFLLSATFNASFLLKLQKWTQKKEKGKKLSRMKLLLKH 82
Q +L + G++ FF L+L S N+ L + + + + S +
Sbjct: 53 QTDLHYVLKPGEVATASIFFGILWLFSIFGNSLVCLVIHRSRRTQ------STTNYFVVS 106
Query: 83 LTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSLA 142
+ A+LL ++ P + T +W G CKV+ Y + + ++++ I +DR
Sbjct: 107 MACADLLISVASTPFVLLQFTTGRWTLGSATCKVVRYFQYLTPGVQIYVLLSICIDRFYT 166
Query: 143 ITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTHCSF 202
I PL+ K + + + M+ +WI + F P L+ + S +HC++
Sbjct: 167 IVYPLSFKVSREKAKKMIAASWIFDAGFVTPVLFFYG--------------SNWDSHCNY 212
Query: 203 --SQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIPR 260
W Y F F+IP ++++ K+I + R+ + ++ N +PR
Sbjct: 213 FLPSSWEGTAYTVIHFLVGFVIPSVLIILFYQKVIKYIWRI---GTDGRTVRRTMNIVPR 269
Query: 261 ARLKTLKMTVAFATSFTVCWTPYYVLGIWY 290
++KT+KM + F + W P++V +W+
Sbjct: 270 TKVKTIKMFLILNLLFLLSWLPFHVAQLWH 299
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 79.7 bits (195), Expect = 3e-15
Identities = 57/249 (22%), Positives = 115/249 (46%), Gaps = 9/249 (3%)
Query: 80 LKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDR 139
+ +L +A+LL + +P + + +W G +LC ++ Y + ++ + VI+LDR
Sbjct: 89 IANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDR 148
Query: 140 SLAITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQCVTH 199
I L K + ++ ++GLAW +S++ A P L IFR L + ++ +
Sbjct: 149 HRCIVYHLESKISKRISFLIIGLAWGISALLASP-LAIFREYSLIEIIPDFEIVACTEKW 207
Query: 200 CSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSKNNIP 259
+ + Y+ + L+++PL I I F+ TR+ + + + + ++
Sbjct: 208 PGEEKSIYGTVYSLSSLLILYVLPLGI-------ISFSYTRIWSKLKNHVSPGAANDHYH 260
Query: 260 RARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLN-RLSDPVNHFFFLFAFLNPCF 318
+ R KT KM V F V W P + + D ++L+ + + F + A +
Sbjct: 261 QRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFA 320
Query: 319 DPLIYGYFS 327
+PL+YG+ +
Sbjct: 321 NPLLYGWMN 329
>gi|161484640 neuromedin B receptor [Homo sapiens]
Length = 390
Score = 79.7 bits (195), Expect = 3e-15
Identities = 60/250 (24%), Positives = 112/250 (44%), Gaps = 15/250 (6%)
Query: 78 LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISL 137
+ + +L +LL L +P+D +W G++ CK++ ++L S+ F + +S
Sbjct: 80 IFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSA 139
Query: 138 DRSLAITRPLALKSNSKVGQSMVGL--AWILSSVFAGPQLYIFRMIHLADSSGQTKVFSQ 195
DR AI P+ ++++ + ++ V W++S + A P+ + + SS F+
Sbjct: 140 DRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARI--SSLDNSSFTA 197
Query: 196 CVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVLHQDPHELQLNQSK 255
C+ + + H ++ F F+IPL I+ I I TL + H P E + K
Sbjct: 198 CIPYPQTDE-LHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKK 256
Query: 256 NNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFF-----L 310
R RL K+ + F F CW P ++L ++ F+ N + + H +
Sbjct: 257 QMETRKRL--AKIVLVFVGCFIFCWFPNHILYMYRSFN---YNEIDPSLGHMIVTLVARV 311
Query: 311 FAFLNPCFDP 320
+F N C +P
Sbjct: 312 LSFGNSCVNP 321
>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
Length = 339
Score = 77.8 bits (190), Expect = 1e-14
Identities = 66/257 (25%), Positives = 115/257 (44%), Gaps = 19/257 (7%)
Query: 79 LLKHLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLD 138
L+ + + L +VMP + + WY GE+ CK+ + + A F + IS+D
Sbjct: 61 LIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISID 120
Query: 139 RSLAITRPLALKS--NSKVGQSMVGLAWILSSVFAGPQLYIFRMIHL-ADSSGQTKVFSQ 195
R A+ PL K+ N V M+ ++W + +VFA F MI L + G +++ +
Sbjct: 121 RYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFA------FGMIFLELNFKGAEEIYYK 174
Query: 196 CVTHC-SFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTL---TRVLHQDPHELQL 251
V HC + TF F IP IML +I R++ +LQ+
Sbjct: 175 HV-HCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQI 233
Query: 252 N-QSKNNIPRARLKTLKMTVAFATS-FTVCWTPYYVLGIWYWFDPEMLNRLSDPVNHFFF 309
+ KN I +++ + T+ F +CW P+++ + DP + + +N
Sbjct: 234 GLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTV---MDPFLHYIIPPTLNDVLI 290
Query: 310 LFAFLNPCFDPLIYGYF 326
F +LN F+P++Y +F
Sbjct: 291 WFGYLNSTFNPMVYAFF 307
>gi|223718066 opioid receptor, mu 1 isoform MOR-1G2 [Homo sapiens]
Length = 319
Score = 77.0 bits (188), Expect = 2e-14
Identities = 62/275 (22%), Positives = 116/275 (42%), Gaps = 22/275 (8%)
Query: 57 LLKLQKWTQKKEKGKKLSRMK----LLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEL 112
+++ + + K K + ++MK + + +L LA+ L T +P + + W G +
Sbjct: 1 MMRAKSISTKAGKPSRYTKMKTATNIYIFNLALADALATS-TLPFQSVNYLMGTWPFGTI 59
Query: 113 LCKVLSYLKLFSMYAPAFMMVVISLDRSLAITRPL-ALKSNSKVGQSMVGLA-WILSSVF 170
LCK++ + ++M+ F + +S+DR +A+ P+ AL + ++ + WILSS
Sbjct: 60 LCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAI 119
Query: 171 AGPQLYIFRMIHLADSSGQTKVFSQCVTHCSFSQWWHQAFYNFFTFSCLFIIPLFIMLIC 230
P +++ + S T FS W+ + F FI+P+ I+ +C
Sbjct: 120 GLPVMFMATTKYRQGSIDCTLTFSH-------PTWYWENLLKICVFIFAFIMPVLIITVC 172
Query: 231 NAKIIFTLTRVLHQDPHELQLNQSKNNIPRARLKTLKMTVAFATSFTVCWTPYYVLGIWY 290
+I L V L+ SK R + +M + F VCWTP ++ I
Sbjct: 173 YGLMILRLKSV-------RMLSGSKEKDRNLR-RITRMVLVVVAVFIVCWTPIHIYVIIK 224
Query: 291 WFDPEMLNRLSDPVNHFFFLFAFLNPCFDPLIYGY 325
HF + N C +P++Y +
Sbjct: 225 ALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAF 259
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 76.3 bits (186), Expect = 4e-14
Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 40/280 (14%)
Query: 82 HLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSL 141
+L+LA++L T+ +P + +IT W+ G+ LCKV+ YL+ S+ + I+LDR
Sbjct: 95 NLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWY 154
Query: 142 AITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIHLADS-SGQTKVFSQCVTHC 200
AI PL KS +K ++ + + WI+S + PQ + + + +T +F+ C
Sbjct: 155 AICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVC---- 210
Query: 201 SFSQWWHQAFYNFFTFSCLFII----PLFIMLICNAKIIFTL--------TRVLHQDPHE 248
+ W Y C F++ PL +M++ +I L + V+ +
Sbjct: 211 --DERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKP 268
Query: 249 LQL--------NQSKNNIP---------RARLKTLKMTVAFATSFTVCWTPYYVLGIWYW 291
LQ +K+ + RAR KT +M + F +C+ P +L +
Sbjct: 269 LQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKR 328
Query: 292 FDPEMLNRLSDPVNHFFFLFA----FLNPCFDPLIYGYFS 327
+ + +F F+ + N +P+IY + S
Sbjct: 329 VFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLS 368
>gi|222080095 orexin receptor 1 [Homo sapiens]
Length = 425
Score = 75.9 bits (185), Expect = 5e-14
Identities = 72/282 (25%), Positives = 109/282 (38%), Gaps = 42/282 (14%)
Query: 82 HLTLANLLETLIVMPLDGMWNITVQWYAGELLCKVLSYLKLFSMYAPAFMMVVISLDRSL 141
+L+LA++L T I +P + +IT W G LCKV+ YL+ S+ + I+LDR
Sbjct: 87 NLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWY 146
Query: 142 AITRPLALKSNSKVGQSMVGLAWILSSVFAGPQLYIFRMIH-LADSSGQTKVFSQCVTHC 200
AI PL KS ++ + + W +S PQ + L + + +T++FS C
Sbjct: 147 AICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFSVC---- 202
Query: 201 SFSQWWHQAFYNFFTFSCLFIIPLFIMLICNAKIIFTLTRVL--HQDPHEL--------- 249
+ W Y SC FI+ L A F + R L Q P
Sbjct: 203 --DERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALVRNWKR 260
Query: 250 ------QLNQSKNNIP--------------RARLKTLKMTVAFATSFTVCWTPYYVLGIW 289
L Q + P RAR KT KM + F +C+ P VL +
Sbjct: 261 PSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLPISVLNVL 320
Query: 290 YWFDPEMLNRLSDPVNHFFFLFA----FLNPCFDPLIYGYFS 327
+ F F+ + N +P+IY + S
Sbjct: 321 KRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLS 362
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.138 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,550,033
Number of Sequences: 37866
Number of extensions: 457706
Number of successful extensions: 2387
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 252
Number of HSP's successfully gapped in prelim test: 131
Number of HSP's that attempted gapping in prelim test: 1673
Number of HSP's gapped (non-prelim): 503
length of query: 328
length of database: 18,247,518
effective HSP length: 103
effective length of query: 225
effective length of database: 14,347,320
effective search space: 3228147000
effective search space used: 3228147000
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.