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Search of human proteins with 4503113
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503113 cystatin M precursor [Homo sapiens]
(149 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503113 cystatin M precursor [Homo sapiens] 300 3e-82
gi|4503107 cystatin C precursor [Homo sapiens] 84 3e-17
gi|19882251 cystatin SN precursor [Homo sapiens] 76 1e-14
gi|4503109 cystatin S precursor [Homo sapiens] 70 5e-13
gi|4503105 cystatin SA precursor [Homo sapiens] 70 7e-13
gi|20302139 cystatin F [Homo sapiens] 66 1e-11
gi|19882259 cystatin-like 1 precursor [Homo sapiens] 64 5e-11
gi|19882256 cystatin D precursor [Homo sapiens] 62 2e-10
gi|4504893 kininogen 1 isoform 2 [Homo sapiens] 55 2e-08
gi|156231037 kininogen 1 isoform 1 [Homo sapiens] 55 2e-08
gi|4885163 cystatin 8 precursor [Homo sapiens] 54 4e-08
gi|19882249 cystatin 11 isoform 1 precursor [Homo sapiens] 54 6e-08
gi|18104940 cystatin 9-like precursor [Homo sapiens] 33 0.089
gi|58331240 fetuin B [Homo sapiens] 29 1.3
gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precurso... 28 2.2
gi|18644732 cystatin 11 isoform 2 precursor [Homo sapiens] 27 4.9
gi|52145312 hypothetical protein LOC118611 [Homo sapiens] 27 6.4
gi|38201702 telomerase reverse transcriptase isoform 2 [Homo sap... 27 8.3
gi|109633031 telomerase reverse transcriptase isoform 1 [Homo sa... 27 8.3
gi|62865885 connexin 37 [Homo sapiens] 27 8.3
>gi|4503113 cystatin M precursor [Homo sapiens]
Length = 149
Score = 300 bits (768), Expect = 3e-82
Identities = 149/149 (100%), Positives = 149/149 (100%)
Query: 1 MARSNLPLALGLALVAFCLLALPRDARARPQERMVGELRDLSPDDPQVQKAAQAAVASYN 60
MARSNLPLALGLALVAFCLLALPRDARARPQERMVGELRDLSPDDPQVQKAAQAAVASYN
Sbjct: 1 MARSNLPLALGLALVAFCLLALPRDARARPQERMVGELRDLSPDDPQVQKAAQAAVASYN 60
Query: 61 MGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQ 120
MGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQ
Sbjct: 61 MGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQ 120
Query: 121 QEKLRCDFEVLVVPWQNSSQLLKHNCVQM 149
QEKLRCDFEVLVVPWQNSSQLLKHNCVQM
Sbjct: 121 QEKLRCDFEVLVVPWQNSSQLLKHNCVQM 149
>gi|4503107 cystatin C precursor [Homo sapiens]
Length = 146
Score = 84.3 bits (207), Expect = 3e-17
Identities = 52/143 (36%), Positives = 77/143 (53%), Gaps = 10/143 (6%)
Query: 7 PLALGLALVAFCLLALPRDARARPQE--RMVGELRDLSPDDPQVQKAAQAAVASYNMGSN 64
PL L LA++A L P A + P + R+VG D S ++ V++A AV YN SN
Sbjct: 8 PLLL-LAILAVALAVSPA-AGSSPGKPPRLVGGPMDASVEEEGVRRALDFAVGEYNKASN 65
Query: 65 SIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQ-QEK 123
+Y+ R +++A+ Q+VAG+ YFL +E+G T C KT+ +L CP + K
Sbjct: 66 DMYHSRALQVVRARKQIVAGVNYFLDVELGRTTCTKTQ-----PNLDNCPFHDQPHLKRK 120
Query: 124 LRCDFEVLVVPWQNSSQLLKHNC 146
C F++ VPWQ + L K C
Sbjct: 121 AFCSFQIYAVPWQGTMTLSKSTC 143
>gi|19882251 cystatin SN precursor [Homo sapiens]
Length = 141
Score = 75.9 bits (185), Expect = 1e-14
Identities = 47/148 (31%), Positives = 77/148 (52%), Gaps = 12/148 (8%)
Query: 1 MARSNLPLALGLALVAFCLLALPRDARARPQERMV-GELRDLSPDDPQVQKAAQAAVASY 59
MA+ L L LA +A L P++ ++R++ G + + +D VQ+A A++ Y
Sbjct: 1 MAQYLSTLLLLLATLAVALAWSPKE-----EDRIIPGGIYNADLNDEWVQRALHFAISEY 55
Query: 60 NMGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGA 119
N + YY R +++A+ Q V G+ YF +E+G T C K++ +L TC
Sbjct: 56 NKATKDDYYRRPLRVLRARQQTVGGVNYFFDVEVGRTICTKSQ-----PNLDTCAFHEQP 110
Query: 120 Q-QEKLRCDFEVLVVPWQNSSQLLKHNC 146
+ Q+K C FE+ VPW+N L+K C
Sbjct: 111 ELQKKQLCSFEIYEVPWENRRSLVKSRC 138
>gi|4503109 cystatin S precursor [Homo sapiens]
Length = 141
Score = 70.5 bits (171), Expect = 5e-13
Identities = 44/148 (29%), Positives = 74/148 (50%), Gaps = 12/148 (8%)
Query: 1 MARSNLPLALGLALVAFCLLALPRDARARPQERMV-GELRDLSPDDPQVQKAAQAAVASY 59
MAR L L +A +A L + ++ + R++ G + D +D VQ+A A++ Y
Sbjct: 1 MARPLCTLLLLMATLAGALASSSKE-----ENRIIPGGIYDADLNDEWVQRALHFAISEY 55
Query: 60 NMGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGA 119
N + YY R +++A+ Q G+ YF +E+G T C K++ +L TC
Sbjct: 56 NKATEDEYYRRPLQVLRAREQTFGGVNYFFDVEVGRTICTKSQ-----PNLDTCAFHEQP 110
Query: 120 Q-QEKLRCDFEVLVVPWQNSSQLLKHNC 146
+ Q+K C FE+ VPW++ L+ C
Sbjct: 111 ELQKKQLCSFEIYEVPWEDRMSLVNSRC 138
>gi|4503105 cystatin SA precursor [Homo sapiens]
Length = 141
Score = 70.1 bits (170), Expect = 7e-13
Identities = 42/141 (29%), Positives = 73/141 (51%), Gaps = 12/141 (8%)
Query: 8 LALGLALVAFCLLALPRDARARPQERMV-GELRDLSPDDPQVQKAAQAAVASYNMGSNSI 66
L L LA A L P++ ++R++ G + D +D +VQ+A ++ YN +
Sbjct: 8 LLLLLATQAVALAWSPQE-----EDRIIEGGIYDADLNDERVQRALHFVISEYNKATEDE 62
Query: 67 YYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQ-QEKLR 125
YY R +++A+ Q+V G+ YF +E+G T C K++ +L TC + Q+K
Sbjct: 63 YYRRLLRVLRAREQIVGGVNYFFDIEVGRTICTKSQ-----PNLDTCAFHEQPELQKKQL 117
Query: 126 CDFEVLVVPWQNSSQLLKHNC 146
C F++ VPW++ L+ C
Sbjct: 118 CSFQIYEVPWEDRMSLVNSRC 138
>gi|20302139 cystatin F [Homo sapiens]
Length = 167
Score = 65.9 bits (159), Expect = 1e-11
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 13/131 (9%)
Query: 14 LVAFCLLALPRDARARPQ--------ERMVGELRDLSPDDPQVQKAAQAAVASYNMGSNS 65
L+AFC L L P G + + +DP V +AA+ +V +N +N
Sbjct: 29 LLAFCCLVLSTTGGPSPDTCSQDLNSRVKPGFPKTIKTNDPGVLQAARYSVEKFNNCTND 88
Query: 66 IYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAG-AQQEKL 124
++ F+++ I +A Q+V G+KY L +E+G T C+K + H+ L C ++ L
Sbjct: 89 MFLFKESRITRALVQIVKGLKYMLEVEIGRTTCKKNQ----HLRLDDCDFQTNHTLKQTL 144
Query: 125 RCDFEVLVVPW 135
C EV VVPW
Sbjct: 145 SCYSEVWVVPW 155
>gi|19882259 cystatin-like 1 precursor [Homo sapiens]
Length = 145
Score = 63.9 bits (154), Expect = 5e-11
Identities = 28/93 (30%), Positives = 54/93 (58%), Gaps = 5/93 (5%)
Query: 56 VASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPL 115
+ SYN SN Y +R +I++Q QL G++Y +T+++G T C++ + ++CPL
Sbjct: 49 IQSYNNASNDTYLYRVQRLIRSQMQLTTGVEYIVTVKIGWTKCKRNDTSN-----SSCPL 103
Query: 116 AAGAQQEKLRCDFEVLVVPWQNSSQLLKHNCVQ 148
+ ++ L C+ + +PW N QL ++C++
Sbjct: 104 QSKKLRKSLICESLIYTMPWINYFQLWNNSCLE 136
>gi|19882256 cystatin D precursor [Homo sapiens]
Length = 142
Score = 61.6 bits (148), Expect = 2e-10
Identities = 40/145 (27%), Positives = 69/145 (47%), Gaps = 14/145 (9%)
Query: 7 PLALGLALVAFCLLALPRDARARPQERMVGELRDLSPDDPQVQKAAQAAVASYNMGSNSI 66
P+ L L+ ++A+ A A+ + + G + +D VQ A A++ YN N
Sbjct: 4 PMHTPLLLLTALMVAVAGSASAQSRT-LAGGIHATDLNDKSVQCALDFAISEYNKVINKD 62
Query: 67 -YYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQQEKLR 125
YY R ++ A Q+V G+ Y+ ++ G T C K++ +L CP Q KL+
Sbjct: 63 EYYSRPLQVMAAYQQIVGGVNYYFNVKFGRTTCTKSQ-----PNLDNCPF---NDQPKLK 114
Query: 126 ----CDFEVLVVPWQNSSQLLKHNC 146
C F++ VPW++ +L + C
Sbjct: 115 EEEFCSFQINEVPWEDKISILNYKC 139
>gi|4504893 kininogen 1 isoform 2 [Homo sapiens]
Length = 427
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 7/108 (6%)
Query: 30 PQERMVGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFL 89
P + VG RD+ + P++++ + N +N+ +YF+ ++ KA+ Q+VAG KYF+
Sbjct: 260 PTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFI 319
Query: 90 TMEMGSTDCRKTRVTGDHVDLT-TCPLAAGAQQEKLRCDFEVLVVPWQ 136
T C K + +LT +C Q L C+ EV VVPW+
Sbjct: 320 DFVARETTCSKE----SNEELTESCETKKLGQ--SLDCNAEVYVVPWE 361
Score = 32.3 bits (72), Expect = 0.15
Identities = 15/66 (22%), Positives = 32/66 (48%)
Query: 35 VGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMG 94
+G + +S P ++ + + +N + F + +AQ Q+VAG+ + +T +
Sbjct: 143 LGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLNFRITYSIV 202
Query: 95 STDCRK 100
T+C K
Sbjct: 203 QTNCSK 208
>gi|156231037 kininogen 1 isoform 1 [Homo sapiens]
Length = 644
Score = 55.5 bits (132), Expect = 2e-08
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 7/108 (6%)
Query: 30 PQERMVGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFL 89
P + VG RD+ + P++++ + N +N+ +YF+ ++ KA+ Q+VAG KYF+
Sbjct: 260 PTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFKIDNVKKARVQVVAGKKYFI 319
Query: 90 TMEMGSTDCRKTRVTGDHVDLT-TCPLAAGAQQEKLRCDFEVLVVPWQ 136
T C K + +LT +C Q L C+ EV VVPW+
Sbjct: 320 DFVARETTCSKE----SNEELTESCETKKLGQ--SLDCNAEVYVVPWE 361
Score = 32.3 bits (72), Expect = 0.15
Identities = 15/66 (22%), Positives = 32/66 (48%)
Query: 35 VGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMG 94
+G + +S P ++ + + +N + F + +AQ Q+VAG+ + +T +
Sbjct: 143 LGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLNEVKRAQRQVVAGLNFRITYSIV 202
Query: 95 STDCRK 100
T+C K
Sbjct: 203 QTNCSK 208
>gi|4885163 cystatin 8 precursor [Homo sapiens]
Length = 142
Score = 54.3 bits (129), Expect = 4e-08
Identities = 37/138 (26%), Positives = 64/138 (46%), Gaps = 11/138 (7%)
Query: 15 VAFCLLALPRD--ARARPQERMVGELRDLSP---DDPQVQKAAQAAVASYNMGSNSIYYF 69
++ LL +P AR P++ G LR L P + V++ A+ YN S Y F
Sbjct: 7 LSLILLTIPLALVARKDPKKNETGVLRKLKPVNASNANVKQCLWFAMQEYNKESEDKYVF 66
Query: 70 RDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQ-QEKLRCDF 128
++AQ Q+ ++Y + +E+ +DCRK T + C + ++ + KL C F
Sbjct: 67 LVVKTLQAQLQVTNLLEYLIDVEIARSDCRKPLSTNE-----ICAIQENSKLKRKLSCSF 121
Query: 129 EVLVVPWQNSSQLLKHNC 146
V +PW +++ C
Sbjct: 122 LVGALPWNGEFTVMEKKC 139
>gi|19882249 cystatin 11 isoform 1 precursor [Homo sapiens]
Length = 138
Score = 53.5 bits (127), Expect = 6e-08
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 11/135 (8%)
Query: 12 LALVAFCLLALPRDARARPQERMVGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRD 71
L + L+ALP AR ++ + ++ + + + Q YN S+ Y+FR
Sbjct: 12 LLAILLTLMALPYQAR----KKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKYHFRI 67
Query: 72 THIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVDLTTCPLAAGAQQEKLRCDFEVL 131
++K Q Q+ ++Y L +EM T C+K + T C +++ C F V
Sbjct: 68 FRVLKVQRQVTDHLEYHLNVEMQWTTCQKP-------ETTNCVPQERELHKQVNCFFSVF 120
Query: 132 VVPWQNSSQLLKHNC 146
VPW ++L +C
Sbjct: 121 AVPWFEQYKILNKSC 135
>gi|18104940 cystatin 9-like precursor [Homo sapiens]
Length = 147
Score = 33.1 bits (74), Expect = 0.089
Identities = 23/96 (23%), Positives = 37/96 (38%), Gaps = 7/96 (7%)
Query: 55 AVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYF-LTMEMGSTDCRKTRVTGDHVDLTTC 113
AV ++N S Y +R HI+ + + V F + + +G T C K D+ C
Sbjct: 54 AVHTFNQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFED-----DIDNC 108
Query: 114 PLAAGAQ-QEKLRCDFEVLVVPWQNSSQLLKHNCVQ 148
+ C F + PW LL C++
Sbjct: 109 HFQESTELNNTFTCFFTISTRPWMTQFSLLNKTCLE 144
>gi|58331240 fetuin B [Homo sapiens]
Length = 382
Score = 29.3 bits (64), Expect = 1.3
Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Query: 47 QVQKAAQAAVASYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVT 104
QV +AA ++A YN + S Y + +A SQ V G YF+ + + C K++ +
Sbjct: 166 QVLEAATESLAKYNNENTSKQYSL-FKVTRASSQWVVGPSYFVEYLIKESPCTKSQAS 222
>gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precursor
[Homo sapiens]
Length = 358
Score = 28.5 bits (62), Expect = 2.2
Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 5/52 (9%)
Query: 19 LLALPRDARARPQERMVGELR-----DLSPDDPQVQKAAQAAVASYNMGSNS 65
+L +PR A + ++ +L D +PDDPQ Q+ Q A+Y + S+S
Sbjct: 29 ILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDS 80
>gi|18644732 cystatin 11 isoform 2 precursor [Homo sapiens]
Length = 103
Score = 27.3 bits (59), Expect = 4.9
Identities = 9/27 (33%), Positives = 16/27 (59%)
Query: 120 QQEKLRCDFEVLVVPWQNSSQLLKHNC 146
Q++++ C F V VPW ++L +C
Sbjct: 74 QRQQVNCFFSVFAVPWFEQYKILNKSC 100
Score = 26.9 bits (58), Expect = 6.4
Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 12 LALVAFCLLALPRDARARPQERMVGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRD 71
L + L+ALP AR ++ + ++ + + + Q YN S+ Y+FR
Sbjct: 12 LLAILLTLMALPYQAR----KKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKYHFRI 67
Query: 72 THIIKAQSQLV 82
++K Q Q V
Sbjct: 68 FRVLKVQRQQV 78
>gi|52145312 hypothetical protein LOC118611 [Homo sapiens]
Length = 699
Score = 26.9 bits (58), Expect = 6.4
Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 2/79 (2%)
Query: 64 NSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDHVD--LTTCPLAAGAQQ 121
+SIYY + + + +A K ++ + +C R+T D VD + P++ +Q
Sbjct: 262 DSIYYVDKSLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQ 321
Query: 122 EKLRCDFEVLVVPWQNSSQ 140
E L D +++ W Q
Sbjct: 322 ELLEGDQDLVGQRWNPGLQ 340
>gi|38201702 telomerase reverse transcriptase isoform 2 [Homo
sapiens]
Length = 1120
Score = 26.6 bits (57), Expect = 8.3
Identities = 16/32 (50%), Positives = 20/32 (62%), Gaps = 3/32 (9%)
Query: 13 ALVAFCLLALPRDAR---ARPQERMVGELRDL 41
ALVA CL+ +P DAR A P R V L++L
Sbjct: 49 ALVAQCLVCVPWDARPPPAAPSFRQVSCLKEL 80
>gi|109633031 telomerase reverse transcriptase isoform 1 [Homo
sapiens]
Length = 1132
Score = 26.6 bits (57), Expect = 8.3
Identities = 16/32 (50%), Positives = 20/32 (62%), Gaps = 3/32 (9%)
Query: 13 ALVAFCLLALPRDAR---ARPQERMVGELRDL 41
ALVA CL+ +P DAR A P R V L++L
Sbjct: 49 ALVAQCLVCVPWDARPPPAAPSFRQVSCLKEL 80
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 26.6 bits (57), Expect = 8.3
Identities = 15/31 (48%), Positives = 19/31 (61%), Gaps = 3/31 (9%)
Query: 24 RDARARPQERMVGELRDLSPDDPQVQKAAQA 54
R+ R R +E GELR L DPQV++A A
Sbjct: 102 REERLRQKE---GELRALPAKDPQVERALAA 129
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,050,669
Number of Sequences: 37866
Number of extensions: 184557
Number of successful extensions: 460
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 431
Number of HSP's gapped (non-prelim): 25
length of query: 149
length of database: 18,247,518
effective HSP length: 93
effective length of query: 56
effective length of database: 14,725,980
effective search space: 824654880
effective search space used: 824654880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.