Search of human proteins with 4501989

Search of human proteins with 4501989

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4501989 alpha-fetoprotein precursor [Homo sapiens]
         (609 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4501989 alpha-fetoprotein precursor [Homo sapiens]                1236   0.0  
gi|4502027 albumin preproprotein [Homo sapiens]                       500   e-141
gi|4501987 afamin precursor [Homo sapiens]                            480   e-135
gi|32483410 vitamin D-binding protein precursor [Homo sapiens]        106   7e-23
gi|239750077 PREDICTED: hypothetical protein [Homo sapiens]            33   0.76 
gi|223029410 talin 1 [Homo sapiens]                                    32   1.3  
gi|117500790 FERM domain containing 3 [Homo sapiens]                   30   6.5  
gi|4502263 activating transcription factor 3 isoform 1 [Homo sap...    30   8.4  
gi|71902536 activating transcription factor 3 isoform 1 [Homo sa...    30   8.4  
gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precurs...    30   8.4  
gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precurs...    30   8.4  

>gi|4501989 alpha-fetoprotein precursor [Homo sapiens]
          Length = 609

 Score = 1236 bits (3198), Expect = 0.0
 Identities = 609/609 (100%), Positives = 609/609 (100%)

Query: 1   MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATY 60
           MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATY
Sbjct: 1   MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATY 60

Query: 61  KEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEG 120
           KEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEG
Sbjct: 61  KEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEG 120

Query: 121 RHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILL 180
           RHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILL
Sbjct: 121 RHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILL 180

Query: 181 WAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITV 240
           WAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITV
Sbjct: 181 WAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITV 240

Query: 241 TKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKIT 300
           TKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKIT
Sbjct: 241 TKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKIT 300

Query: 301 ECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSR 360
           ECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSR
Sbjct: 301 ECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSR 360

Query: 361 RHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQ 420
           RHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQ
Sbjct: 361 RHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQ 420

Query: 421 KLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADII 480
           KLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADII
Sbjct: 421 KLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADII 480

Query: 481 IGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQA 540
           IGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQA
Sbjct: 481 IGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQA 540

Query: 541 QGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLI 600
           QGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLI
Sbjct: 541 QGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLI 600

Query: 601 SKTRAALGV 609
           SKTRAALGV
Sbjct: 601 SKTRAALGV 609


>gi|4502027 albumin preproprotein [Homo sapiens]
          Length = 609

 Score =  500 bits (1288), Expect = e-141
 Identities = 244/610 (40%), Positives = 363/610 (59%), Gaps = 2/610 (0%)

Query: 1   MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATY 60
           MKWV  I L+FL +   SR + R +   + +   ++   E +   L  I FAQ++Q+  +
Sbjct: 1   MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF 60

Query: 61  KEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGH-SDCCSQSEE 119
           ++  K+V +     +    DE +  C ++    F ++LC    + E YG  +DCC++ E 
Sbjct: 61  EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP 120

Query: 120 GRHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTIL 179
            R+ CFL HK   P ++P    PE    C A+ ++ ETF+ K++YEIARRHP+ YAP +L
Sbjct: 121 ERNECFLQHKDDNP-NLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELL 179

Query: 180 LWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAIT 239
            +A RY      CC+A +   C   K   +  E + SS   +  CA ++ FG R F+A  
Sbjct: 180 FFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWA 239

Query: 240 VTKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKI 299
           V +LSQ+F K  F E+ KLV D+  VH  CC GD+L+C  D   +  YIC  QD++S+K+
Sbjct: 240 VARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKL 299

Query: 300 TECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYS 359
            ECC+   LE+  CI   ENDE P  L      F+  +D  +  +  K++FL  F++EY+
Sbjct: 300 KECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYA 359

Query: 360 RRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLF 419
           RRHP  +V ++LR+AK Y+  LEKC    +P EC  K  +E +  ++E Q L K++C LF
Sbjct: 360 RRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELF 419

Query: 420 QKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADI 479
           ++LGEY  QNA LV YTKK PQ+++  L+ ++R +    + CC+  E K + C E    +
Sbjct: 420 EQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSV 479

Query: 480 IIGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQ 539
           ++  LC+ HE TPV+  V +CCT S  NRRPCFS+L VDETYVP  F+ + F FH D+C 
Sbjct: 480 VLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICT 539

Query: 540 AQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKL 599
                 Q  KQ  L+ LVK KP+ T+EQL+AV+ DF+  +EKCC+  ++E CFAEEG+KL
Sbjct: 540 LSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKL 599

Query: 600 ISKTRAALGV 609
           ++ ++AALG+
Sbjct: 600 VAASQAALGL 609


>gi|4501987 afamin precursor [Homo sapiens]
          Length = 599

 Score =  480 bits (1236), Expect = e-135
 Identities = 234/592 (39%), Positives = 361/592 (60%), Gaps = 3/592 (0%)

Query: 8   FLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMV 67
           F+ FL   TES TL      I +  +S Q   E ++  +  I FAQ+VQEAT++E+ K+V
Sbjct: 9   FIFFLFFLTESLTLPTQPRDIENF-NSTQKFIEDNIEYITIIAFAQYVQEATFEEMEKLV 67

Query: 68  KDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLA 127
           KD +   ++   D+    C +       E++C  + + +K+  S CCS+ +  R  CF  
Sbjct: 68  KDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFY 127

Query: 128 HKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDK 187
           +KK     +P F   +P   C+AYE +RE+ +N F+YE+ARR+PF++APT+L  A  +++
Sbjct: 128 NKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLTVAVHFEE 187

Query: 188 IIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKF 247
           +  SCC+ +N V C QT+A  VT+ L+  S   +H C  +  FGT+    I +  LSQKF
Sbjct: 188 VAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQKF 247

Query: 248 TKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKITECCKLTT 307
            K+ F E+  LV DV+  ++ CC GDV+ C++D  K+M++ICS+QD++S+KI ECC+   
Sbjct: 248 PKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIKECCEKKI 307

Query: 308 LERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAV 367
            ERGQCII++  D++P+ LS    +F    +  Q    + + F A F  EYSRRHP L++
Sbjct: 308 PERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPDLSI 367

Query: 368 SVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYL 427
             +LR+ + Y++LL  C  TENP  C    E++  +  ++S  + ++ C  FQ LG+  L
Sbjct: 368 PELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQNLGKDGL 427

Query: 428 QNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIR 487
           +  +L+  TK APQL++ EL+++  KM     TCC LSE+   AC +  AD++ G LC  
Sbjct: 428 KYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEE--FACVDNLADLVFGELCGV 485

Query: 488 HEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQT 547
           +E   +NP V  CC +++A RRPCF SL  D+TYVPP FS D F FH D+CQ+Q   LQ 
Sbjct: 486 NENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQNEELQR 545

Query: 548 MKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKL 599
               FL+NLVK K ++T+E+L+++  +F+ +++KCC+ +  EVCF EE  K+
Sbjct: 546 KTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKI 597



 Score =  110 bits (274), Expect = 5e-24
 Identities = 78/409 (19%), Positives = 169/409 (41%), Gaps = 17/409 (4%)

Query: 202 FQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLD 261
           F T++ T+  + R+    N       + F     + IT+   +Q   +  F E++KLV D
Sbjct: 15  FLTESLTLPTQPRDIENFNS-----TQKFIEDNIEYITIIAFAQYVQEATFEEMEKLVKD 69

Query: 262 VAHVHEHCCRGDVL-DCLQDGEKIMSYICSQQDTLSNK--ITECCKLTTLERGQCIIHAE 318
           +    + C     L +C +    ++       + L  K   + CC     +R  C  +  
Sbjct: 70  MVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQRRLCFFY-- 127

Query: 319 NDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQ 378
           N +   G  P       +     + S  +++ L  F++E +RR+P +    +L VA  ++
Sbjct: 128 NKKSDVGFLPPFPTLDPEEKCQAYESNRESL-LNHFLYEVARRNPFVFAPTLLTVAVHFE 186

Query: 379 ELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKK 438
           E+ + C + +N + C       + +Y++   +  K  CG   K G   +   ++   ++K
Sbjct: 187 EVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYIAILSQK 246

Query: 439 APQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNPGVG 498
            P++   EL+++   +++    CC   E  ++ C    + ++  H+C + +   ++  + 
Sbjct: 247 FPKIEFKELISLVEDVSSNYDGCC---EGDVVQCIRDTSKVM-NHICSKQDS--ISSKIK 300

Query: 499 QCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVK 558
           +CC      R  C  +   D+     +  + KF   +++CQ +     T   +F     +
Sbjct: 301 ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSR 360

Query: 559 QKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLISKTRAAL 607
           + P ++  +L  ++  +  LL  CC  +    C+     K    T  +L
Sbjct: 361 RHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSL 409


>gi|32483410 vitamin D-binding protein precursor [Homo sapiens]
          Length = 474

 Score =  106 bits (264), Expect = 7e-23
 Identities = 98/481 (20%), Positives = 195/481 (40%), Gaps = 25/481 (5%)

Query: 9   LIFLLNFTESRTLHRN-EYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMV 67
           L+ LL       L R  +Y    +   +    +     L+ + +++     T+++VS++V
Sbjct: 5   LVLLLAVAFGHALERGRDYEKNKVCKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLV 64

Query: 68  KDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKY-GHSDCCSQSEEGRHNCFL 126
           K+ ++  E    +     C + +  A   + C        + G ++CC++    R  C +
Sbjct: 65  KEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAECCTKEGLERKLC-M 123

Query: 127 AHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYD 186
           A  K  P   P +  P     CEA+ +D + + N+F++E +  +       ++ +   Y 
Sbjct: 124 AALKHQPQEFPTYVEPTNDEICEAFRKDPKEYANQFMWEYSTNYGQAPLSLLVSYTKSYL 183

Query: 187 KIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQK 246
            ++ SCC + +   CF  K     K L   + L+   C+    +G +  +   + KL+QK
Sbjct: 184 SMVGSCCTSASPTVCF-LKERLQLKHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQK 242

Query: 247 FTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCL-QDGEKIMSYICSQQDTLSNKITECC-K 304
               +  ++  L  D+ ++   CC     DC+ ++  +    +C    T ++K  +CC +
Sbjct: 243 VPTADLEDVLPLAEDITNILSKCCESASEDCMAKELPEHTVKLCDNLSTKNSKFEDCCQE 302

Query: 305 LTTLERGQCIIHAENDEKPEGLSPNL--NRFLGDRDFNQFSSGEKNIFLASFVHEYSRRH 362
            T ++   C       + PE     L  N+ + D        G   + +  +  E SRR 
Sbjct: 303 KTAMDVFVCTYFMPAAQLPELPDVELPTNKDVCD-------PGNTKV-MDKYTFELSRR- 353

Query: 363 PQLAVSVILRVAKGYQELLEKCFQTENPLEC-QDKG---EEELQKYIQESQALAKRSCGL 418
             L    + +V +   + L +C   E+   C   KG   ++EL  +I + Q L    C  
Sbjct: 354 THLPEVFLSKVLEPTLKSLGECCDVEDSTTCFNAKGPLLKKELSSFIDKGQEL----CAD 409

Query: 419 FQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAAD 478
           + +      +         K P  T +EL  +  K +  A+ CC ++   L    E  A+
Sbjct: 410 YSENTFTEYKKKLAERLKAKLPDATPTELAKLVNKHSDFASNCCSINSPPLYCDSEIDAE 469

Query: 479 I 479
           +
Sbjct: 470 L 470



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 80/386 (20%), Positives = 150/386 (38%), Gaps = 32/386 (8%)

Query: 224 CAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLDVAHVHEHCC-RGDVLDCLQDGE 282
           C    + G   F ++++   S+KF    F ++ +LV +V  + E CC  G   DC     
Sbjct: 29  CKEFSHLGKEDFTSLSLVLYSRKFPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRT 88

Query: 283 KIMSYICSQQDT---LSNKITECCKLTTLERGQCI--IHAENDEKPEGLSPNLNRFLGDR 337
             +S    + ++   +     ECC    LER  C+  +  +  E P  + P       D 
Sbjct: 89  SALSAKSCESNSPFPVHPGTAECCTKEGLERKLCMAALKHQPQEFPTYVEPT-----NDE 143

Query: 338 DFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKG 397
               F    K  +   F+ EYS  + Q  +S+++   K Y  ++  C  + +P  C  K 
Sbjct: 144 ICEAFRKDPKE-YANQFMWEYSTNYGQAPLSLLVSYTKSYLSMVGSCCTSASPTVCFLKE 202

Query: 398 EEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAAT 457
             +L K++     L+ R C  +   GE   + + L+   +K P     +++ +   +   
Sbjct: 203 RLQL-KHLSLLTTLSNRVCSQYAAYGEKKSRLSNLIKLAQKVPTADLEDVLPLAEDITNI 261

Query: 458 AATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVV 517
            + CC+ + +  +A       +    LC    ++  N     CC    A        + V
Sbjct: 262 LSKCCESASEDCMAKELPEHTV---KLC--DNLSTKNSKFEDCCQEKTA------MDVFV 310

Query: 518 DETYVP----PAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIA 573
              ++P    P   D +   +KD+C      +   K  F ++   ++  + E  L  V+ 
Sbjct: 311 CTYFMPAAQLPELPDVELPTNKDVCDPGNTKVMD-KYTFELS---RRTHLPEVFLSKVLE 366

Query: 574 DFSGLLEKCCQGQEQEVCFAEEGQKL 599
                L +CC  ++   CF  +G  L
Sbjct: 367 PTLKSLGECCDVEDSTTCFNAKGPLL 392


>gi|239750077 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 903

 Score = 33.1 bits (74), Expect = 0.76
 Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 60  YKEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDC 113
           ++ +S++   +  ++EKP G+E+ S      LP+F   LC  + I +  G  DC
Sbjct: 254 WRFLSRIFCSSFFSLEKPAGEEEGSAAEAQTLPSFC--LCLSQAIQQAAGEGDC 305


>gi|223029410 talin 1 [Homo sapiens]
          Length = 2541

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 42/195 (21%), Positives = 77/195 (39%), Gaps = 29/195 (14%)

Query: 315 IHAENDEKPEGLSPNLNRFLGDRDFNQFSS-GEKNIFLASFVHEYSRRHPQLAVSV---- 369
           IH++ D    G +  +N   GD     +++ G     ++S + E SR    LA  +    
Sbjct: 543 IHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEG 602

Query: 370 -----ILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGE 424
                +L+ AKG    + +  ++  P   + +     Q  +Q +  + + S  L Q++GE
Sbjct: 603 GSGRPLLQAAKGLAGAVSELLRSAQPASAEPR-----QNLLQAAGNVGQASGELLQQIGE 657

Query: 425 YYLQNAFLVAYTKKAPQLTSSELMAITRKMAAT--------------AATCCQLSEDKLL 470
                 F  A  + A  + S+    + +  +                AAT C LS  +L+
Sbjct: 658 SDTDPHFQDALMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLV 717

Query: 471 ACGEGAADIIIGHLC 485
           AC +  A  I   +C
Sbjct: 718 ACTKVVAPTISSPVC 732


>gi|117500790 FERM domain containing 3 [Homo sapiens]
          Length = 597

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 30/133 (22%), Positives = 53/133 (39%), Gaps = 16/133 (12%)

Query: 277 CLQDGEKIMSYICSQQDTLSNKITEC-CKLTTLERGQCIIHAENDEKPEGLSPNLNRFLG 335
           C+  G + M  I  +  ++ +   E  C +  L+  +   H + + K         +FL 
Sbjct: 7   CVPRGRRTMKMIHFRSSSVKSLSQEMRCTIRLLDDSEISCHIQRETK--------GQFLI 58

Query: 336 DRDFNQFSSGEKNIFLASFVHEYSRRH---PQLAVSVILRVAKGYQELLEKCFQTENPLE 392
           D   N +S  EK+ F   +V    +RH   P  ++   ++    Y       F    PL 
Sbjct: 59  DHICNYYSLLEKDYFGIRYVDPEKQRHWLEPNKSIFKQMKTHPPYTMCFRVKFYPHEPL- 117

Query: 393 CQDKGEEELQKYI 405
              K +EEL +Y+
Sbjct: 118 ---KIKEELTRYL 127


>gi|4502263 activating transcription factor 3 isoform 1 [Homo
           sapiens]
          Length = 181

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 36/138 (26%), Positives = 59/138 (42%), Gaps = 18/138 (13%)

Query: 200 ECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTK--LSQKFTKVNFT---- 253
           E F      V +ELR  ++ N+H C  M +      +++TV+   L    TK        
Sbjct: 32  EDFANLTPFVKEELR-FAIQNKHLCHRMSS----ALESVTVSDRPLGVSITKAEVAPEED 86

Query: 254 EIQKLVLDVAHVHEHCCRG---DVLDCLQ-DGEKIMSY---ICSQQDTLSNKITECCKLT 306
           E +K   +   +    CR    +  +CLQ + EK+ S    + +Q + L N+      + 
Sbjct: 87  ERKKRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYML 146

Query: 307 TLERGQCIIHAENDEKPE 324
            L R  CI+ A+N   PE
Sbjct: 147 NLHRPTCIVRAQNGRTPE 164


>gi|71902536 activating transcription factor 3 isoform 1 [Homo
           sapiens]
          Length = 181

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 36/138 (26%), Positives = 59/138 (42%), Gaps = 18/138 (13%)

Query: 200 ECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTK--LSQKFTKVNFT---- 253
           E F      V +ELR  ++ N+H C  M +      +++TV+   L    TK        
Sbjct: 32  EDFANLTPFVKEELR-FAIQNKHLCHRMSS----ALESVTVSDRPLGVSITKAEVAPEED 86

Query: 254 EIQKLVLDVAHVHEHCCRG---DVLDCLQ-DGEKIMSY---ICSQQDTLSNKITECCKLT 306
           E +K   +   +    CR    +  +CLQ + EK+ S    + +Q + L N+      + 
Sbjct: 87  ERKKRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYML 146

Query: 307 TLERGQCIIHAENDEKPE 324
            L R  CI+ A+N   PE
Sbjct: 147 NLHRPTCIVRAQNGRTPE 164


>gi|14270499 protocadherin gamma subfamily B, 4 isoform 2 precursor
           [Homo sapiens]
          Length = 803

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 8/72 (11%)

Query: 516 VVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADF 575
           V  E+ VPP +S+    +  +LC A      T K EF  N +K   Q++  Q + +  D 
Sbjct: 731 VKSESVVPPNYSEGTLPYSYNLCVA-----HTGKTEF--NFLKCSEQLSSGQ-DILCGDS 782

Query: 576 SGLLEKCCQGQE 587
           SG L   C   E
Sbjct: 783 SGALFPLCNSSE 794


>gi|13470082 protocadherin gamma subfamily B, 4 isoform 1 precursor
           [Homo sapiens]
          Length = 923

 Score = 29.6 bits (65), Expect = 8.4
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 8/72 (11%)

Query: 516 VVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADF 575
           V  E+ VPP +S+    +  +LC A      T K EF  N +K   Q++  Q + +  D 
Sbjct: 731 VKSESVVPPNYSEGTLPYSYNLCVA-----HTGKTEF--NFLKCSEQLSSGQ-DILCGDS 782

Query: 576 SGLLEKCCQGQE 587
           SG L   C   E
Sbjct: 783 SGALFPLCNSSE 794


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,825,078
Number of Sequences: 37866
Number of extensions: 1046528
Number of successful extensions: 2777
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2721
Number of HSP's gapped (non-prelim): 18
length of query: 609
length of database: 18,247,518
effective HSP length: 108
effective length of query: 501
effective length of database: 14,157,990
effective search space: 7093152990
effective search space used: 7093152990
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.