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Search of human proteins with 126131104
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|126131104 fibrocystin isoform 2 [Homo sapiens]
(3396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|126131104 fibrocystin isoform 2 [Homo sapiens] 6893 0.0
gi|126131102 fibrocystin isoform 1 [Homo sapiens] 6875 0.0
gi|126116589 fibrocystin L [Homo sapiens] 694 0.0
gi|7019555 transmembrane protein 2 isoform a [Homo sapiens] 66 5e-10
gi|209447096 transmembrane protein 2 isoform b [Homo sapiens] 65 9e-10
gi|38638698 KIAA1199 [Homo sapiens] 61 2e-08
gi|157694524 plexin D1 [Homo sapiens] 52 1e-05
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 44 0.003
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 41 0.023
gi|49355818 plexin A1 [Homo sapiens] 40 0.030
gi|194272180 plexin B1 [Homo sapiens] 39 0.067
gi|40254442 plexin B1 [Homo sapiens] 39 0.067
gi|23308722 TTK protein kinase [Homo sapiens] 38 0.20
gi|149363636 plexin B2 [Homo sapiens] 37 0.26
gi|113722116 plexin A2 [Homo sapiens] 36 0.57
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 35 0.97
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 35 0.97
gi|59710104 plexin A3 [Homo sapiens] 35 0.97
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s... 33 4.8
gi|217416372 coiled-coil domain containing 142 [Homo sapiens] 33 4.8
gi|223029410 talin 1 [Homo sapiens] 33 6.3
>gi|126131104 fibrocystin isoform 2 [Homo sapiens]
Length = 3396
Score = 6893 bits (17884), Expect = 0.0
Identities = 3396/3396 (100%), Positives = 3396/3396 (100%)
Query: 1 MTAWLISLMSIEVLLLAVRHLSLHIEPEEGSLAGGTWITVIFDGLELGVLYPNNGSQLEI 60
MTAWLISLMSIEVLLLAVRHLSLHIEPEEGSLAGGTWITVIFDGLELGVLYPNNGSQLEI
Sbjct: 1 MTAWLISLMSIEVLLLAVRHLSLHIEPEEGSLAGGTWITVIFDGLELGVLYPNNGSQLEI 60
Query: 61 HLVNVNMVVPALRSVPCDVFPVFLDLPVVTCRTRSVLSEAHEGLYFLEAYFGGQLVSSPN 120
HLVNVNMVVPALRSVPCDVFPVFLDLPVVTCRTRSVLSEAHEGLYFLEAYFGGQLVSSPN
Sbjct: 61 HLVNVNMVVPALRSVPCDVFPVFLDLPVVTCRTRSVLSEAHEGLYFLEAYFGGQLVSSPN 120
Query: 121 PGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLETFDFDAEYIDSPVIL 180
PGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLETFDFDAEYIDSPVIL
Sbjct: 121 PGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLETFDFDAEYIDSPVIL 180
Query: 181 EAQGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCHVEGDYIGSQNVSFSVFNKGKSMVH 240
EAQGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCHVEGDYIGSQNVSFSVFNKGKSMVH
Sbjct: 181 EAQGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCHVEGDYIGSQNVSFSVFNKGKSMVH 240
Query: 241 KKAWLISAKQDLFLYQTHSEILSVFPETGSLGGRTNITITGDFFDNSAQVTIAGIPCDIR 300
KKAWLISAKQDLFLYQTHSEILSVFPETGSLGGRTNITITGDFFDNSAQVTIAGIPCDIR
Sbjct: 241 KKAWLISAKQDLFLYQTHSEILSVFPETGSLGGRTNITITGDFFDNSAQVTIAGIPCDIR 300
Query: 301 HVSPRKIECTTRAPGKDVRLTTPQPGNRGLLFEVGDAVEGLELTEATPGYRWQIVPNASS 360
HVSPRKIECTTRAPGKDVRLTTPQPGNRGLLFEVGDAVEGLELTEATPGYRWQIVPNASS
Sbjct: 301 HVSPRKIECTTRAPGKDVRLTTPQPGNRGLLFEVGDAVEGLELTEATPGYRWQIVPNASS 360
Query: 361 PFGFWSQEGQPFRARLSGFFVAPETNNYTFWIQADSQASLHFSWSEEPRTKVKVASISVG 420
PFGFWSQEGQPFRARLSGFFVAPETNNYTFWIQADSQASLHFSWSEEPRTKVKVASISVG
Sbjct: 361 PFGFWSQEGQPFRARLSGFFVAPETNNYTFWIQADSQASLHFSWSEEPRTKVKVASISVG 420
Query: 421 TADWFDSWEQNRDEGTWQQKTPKLELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNP 480
TADWFDSWEQNRDEGTWQQKTPKLELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNP
Sbjct: 421 TADWFDSWEQNRDEGTWQQKTPKLELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNP 480
Query: 481 DVVTTYLREKHQIRVRAQRLPEVQVLNVSGRGNFFLTWDNVSSQPIPANATAHLIQTTIE 540
DVVTTYLREKHQIRVRAQRLPEVQVLNVSGRGNFFLTWDNVSSQPIPANATAHLIQTTIE
Sbjct: 481 DVVTTYLREKHQIRVRAQRLPEVQVLNVSGRGNFFLTWDNVSSQPIPANATAHLIQTTIE 540
Query: 541 ELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPA 600
ELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPA
Sbjct: 541 ELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPA 600
Query: 601 AQKGYRLDQYTHLCLAYKGHMNKILKMIVSFTIGFQNMVKNTTCDWSLTRTSPESWQFDC 660
AQKGYRLDQYTHLCLAYKGHMNKILKMIVSFTIGFQNMVKNTTCDWSLTRTSPESWQFDC
Sbjct: 601 AQKGYRLDQYTHLCLAYKGHMNKILKMIVSFTIGFQNMVKNTTCDWSLTRTSPESWQFDC 660
Query: 661 TDLWETCVRCFGDLQPPPANSPVLVHQINLLPLAQETGLFYVDEIIIADTNVTVSQADSG 720
TDLWETCVRCFGDLQPPPANSPVLVHQINLLPLAQETGLFYVDEIIIADTNVTVSQADSG
Sbjct: 661 TDLWETCVRCFGDLQPPPANSPVLVHQINLLPLAQETGLFYVDEIIIADTNVTVSQADSG 720
Query: 721 TARPGGNLVESVSVVGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEEGSGLVLVTTQR 780
TARPGGNLVESVSVVGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEEGSGLVLVTTQR
Sbjct: 721 TARPGGNLVESVSVVGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEEGSGLVLVTTQR 780
Query: 781 RQRTSPPLGGHFRIQLPNTVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDL 840
RQRTSPPLGGHFRIQLPNTVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDL
Sbjct: 781 RQRTSPPLGGHFRIQLPNTVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDL 840
Query: 841 YTCYEHVWTLSWSTQIGDLPNFIRVSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATA 900
YTCYEHVWTLSWSTQIGDLPNFIRVSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATA
Sbjct: 841 YTCYEHVWTLSWSTQIGDLPNFIRVSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATA 900
Query: 901 NQHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDGDINLMIYITGTGFSGDSQ 960
NQHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDGDINLMIYITGTGFSGDSQ
Sbjct: 901 NQHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDGDINLMIYITGTGFSGDSQ 960
Query: 961 FLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISATGEDLFLNVKPR 1020
FLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISATGEDLFLNVKPR
Sbjct: 961 FLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISATGEDLFLNVKPR 1020
Query: 1021 LDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPRGKDG 1080
LDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPRGKDG
Sbjct: 1021 LDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPRGKDG 1080
Query: 1081 RIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLD 1140
RIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLD
Sbjct: 1081 RIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLD 1140
Query: 1141 VEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFS 1200
VEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFS
Sbjct: 1141 VEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFS 1200
Query: 1201 IEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQIPDA 1260
IEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQIPDA
Sbjct: 1201 IEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQIPDA 1260
Query: 1261 GAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEITNSSLSLHVG 1320
GAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEITNSSLSLHVG
Sbjct: 1261 GAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEITNSSLSLHVG 1320
Query: 1321 GSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSV 1380
GSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSV
Sbjct: 1321 GSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSV 1380
Query: 1381 VLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDHT 1440
VLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDHT
Sbjct: 1381 VLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDHT 1440
Query: 1441 ILCQVSLEGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLT 1500
ILCQVSLEGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLT
Sbjct: 1441 ILCQVSLEGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLT 1500
Query: 1501 TVLIRGQRLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLAPGPHYLSVFYTRNGYA 1560
TVLIRGQRLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLAPGPHYLSVFYTRNGYA
Sbjct: 1501 TVLIRGQRLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLAPGPHYLSVFYTRNGYA 1560
Query: 1561 CSGNVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGA 1620
CSGNVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGA
Sbjct: 1561 CSGNVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGA 1620
Query: 1621 ELIRCIVPTGNGSVALEIEVDGLWYHIGVIGYNKAFTPELISISQSDDILTFAVAQISGA 1680
ELIRCIVPTGNGSVALEIEVDGLWYHIGVIGYNKAFTPELISISQSDDILTFAVAQISGA
Sbjct: 1621 ELIRCIVPTGNGSVALEIEVDGLWYHIGVIGYNKAFTPELISISQSDDILTFAVAQISGA 1680
Query: 1681 ANIDIFIGMSPCVGVSGNHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITA 1740
ANIDIFIGMSPCVGVSGNHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITA
Sbjct: 1681 ANIDIFIGMSPCVGVSGNHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITA 1740
Query: 1741 VTENFGCLGGRLVHVFGAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLC 1800
VTENFGCLGGRLVHVFGAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLC
Sbjct: 1741 VTENFGCLGGRLVHVFGAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLC 1800
Query: 1801 GLKREEDSCEAARHTYVQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAESMFPS 1860
GLKREEDSCEAARHTYVQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAESMFPS
Sbjct: 1801 GLKREEDSCEAARHTYVQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAESMFPS 1860
Query: 1861 FSGLFISPKLERDEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNF 1920
FSGLFISPKLERDEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNF
Sbjct: 1861 FSGLFISPKLERDEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNF 1920
Query: 1921 SLQFCRRWSRTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPGP 1980
SLQFCRRWSRTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPGP
Sbjct: 1921 SLQFCRRWSRTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPGP 1980
Query: 1981 IELRAHAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLH 2040
IELRAHAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLH
Sbjct: 1981 IELRAHAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLH 2040
Query: 2041 GSLPEVIVTCLRATAHALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQ 2100
GSLPEVIVTCLRATAHALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQ
Sbjct: 2041 GSLPEVIVTCLRATAHALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQ 2100
Query: 2101 DTDLYLKSPLRYSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEAN 2160
DTDLYLKSPLRYSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEAN
Sbjct: 2101 DTDLYLKSPLRYSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEAN 2160
Query: 2161 APEGNLQHCLYSMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSL 2220
APEGNLQHCLYSMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSL
Sbjct: 2161 APEGNLQHCLYSMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSL 2220
Query: 2221 TLVGAMRESFIQGCTVRNSFSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISW 2280
TLVGAMRESFIQGCTVRNSFSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISW
Sbjct: 2221 TLVGAMRESFIQGCTVRNSFSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISW 2280
Query: 2281 EAIHGRKDDWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAG 2340
EAIHGRKDDWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAG
Sbjct: 2281 EAIHGRKDDWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAG 2340
Query: 2341 YGYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWES 2400
YGYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWES
Sbjct: 2341 YGYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWES 2400
Query: 2401 AGGAQIFRSSNLRLKNFKVYSCRDFGIDVLESDANTSVTDSLLLGHFAHKGSLCMSSGIK 2460
AGGAQIFRSSNLRLKNFKVYSCRDFGIDVLESDANTSVTDSLLLGHFAHKGSLCMSSGIK
Sbjct: 2401 AGGAQIFRSSNLRLKNFKVYSCRDFGIDVLESDANTSVTDSLLLGHFAHKGSLCMSSGIK 2460
Query: 2461 TPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQLKFTNSSNLVAFPFPH 2520
TPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQLKFTNSSNLVAFPFPH
Sbjct: 2461 TPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQLKFTNSSNLVAFPFPH 2520
Query: 2521 AAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMSIGLAN 2580
AAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMSIGLAN
Sbjct: 2521 AAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMSIGLAN 2580
Query: 2581 TPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSLQYSA 2640
TPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSLQYSA
Sbjct: 2581 TPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSLQYSA 2640
Query: 2641 TFDNFAPGNYLLLVHTDLPPYPDILLRCGSRVGLSFPFLPSPGQNQGCDWFFNSQLRQLT 2700
TFDNFAPGNYLLLVHTDLPPYPDILLRCGSRVGLSFPFLPSPGQNQGCDWFFNSQLRQLT
Sbjct: 2641 TFDNFAPGNYLLLVHTDLPPYPDILLRCGSRVGLSFPFLPSPGQNQGCDWFFNSQLRQLT 2700
Query: 2701 YLVSGEGQVQVILRVKEGMPPTISASTSAPESALKWSLPETWQGVEEGWGGYNNTIPGPG 2760
YLVSGEGQVQVILRVKEGMPPTISASTSAPESALKWSLPETWQGVEEGWGGYNNTIPGPG
Sbjct: 2701 YLVSGEGQVQVILRVKEGMPPTISASTSAPESALKWSLPETWQGVEEGWGGYNNTIPGPG 2760
Query: 2761 DDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVIAGGELKVGTLENPL 2820
DDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVIAGGELKVGTLENPL
Sbjct: 2761 DDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVIAGGELKVGTLENPL 2820
Query: 2821 EKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVHLYSAYPKNSWTHLGADIASGNE 2880
EKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVHLYSAYPKNSWTHLGADIASGNE
Sbjct: 2821 EKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVHLYSAYPKNSWTHLGADIASGNE 2880
Query: 2881 RIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIYERLKHRHIGSVHVTED 2940
RIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIYERLKHRHIGSVHVTED
Sbjct: 2881 RIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIYERLKHRHIGSVHVTED 2940
Query: 2941 GRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSGVLQLLNVEIQNFGSPL 3000
GRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSGVLQLLNVEIQNFGSPL
Sbjct: 2941 GRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSGVLQLLNVEIQNFGSPL 3000
Query: 3001 YSSVEFSNVSAGSWIISSTLHQSCGGGIHAAASHGVLLNDNIVFGTAGHGIDLEGQAYTV 3060
YSSVEFSNVSAGSWIISSTLHQSCGGGIHAAASHGVLLNDNIVFGTAGHGIDLEGQAYTV
Sbjct: 3001 YSSVEFSNVSAGSWIISSTLHQSCGGGIHAAASHGVLLNDNIVFGTAGHGIDLEGQAYTV 3060
Query: 3061 TNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHKCSSCELLWSD 3120
TNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHKCSSCELLWSD
Sbjct: 3061 TNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHKCSSCELLWSD 3120
Query: 3121 NVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGLL 3180
NVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGLL
Sbjct: 3121 NVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGLL 3180
Query: 3181 AVVYVFSAPQNSVKKVQIVLRNSVIVATSSSFDCIQDKVKPHSANLTSTDRAPSNPRGGR 3240
AVVYVFSAPQNSVKKVQIVLRNSVIVATSSSFDCIQDKVKPHSANLTSTDRAPSNPRGGR
Sbjct: 3181 AVVYVFSAPQNSVKKVQIVLRNSVIVATSSSFDCIQDKVKPHSANLTSTDRAPSNPRGGR 3240
Query: 3241 IGILWPVFTSEPNQWPQEPWHKVRNDHSISGIMKLQDVTFSSFVKSCYSDDLDVCILPNA 3300
IGILWPVFTSEPNQWPQEPWHKVRNDHSISGIMKLQDVTFSSFVKSCYSDDLDVCILPNA
Sbjct: 3241 IGILWPVFTSEPNQWPQEPWHKVRNDHSISGIMKLQDVTFSSFVKSCYSDDLDVCILPNA 3300
Query: 3301 ENSGIMHPITAERTRMLKIKDKNKFYFPSLQPRKDLGKVVCPELDCASPRKYLFKDLDGR 3360
ENSGIMHPITAERTRMLKIKDKNKFYFPSLQPRKDLGKVVCPELDCASPRKYLFKDLDGR
Sbjct: 3301 ENSGIMHPITAERTRMLKIKDKNKFYFPSLQPRKDLGKVVCPELDCASPRKYLFKDLDGR 3360
Query: 3361 ALGLPPPVSVFPKTEAEWTASFFNAVTTEQALKISE 3396
ALGLPPPVSVFPKTEAEWTASFFNAVTTEQALKISE
Sbjct: 3361 ALGLPPPVSVFPKTEAEWTASFFNAVTTEQALKISE 3396
>gi|126131102 fibrocystin isoform 1 [Homo sapiens]
Length = 4074
Score = 6875 bits (17838), Expect = 0.0
Identities = 3387/3393 (99%), Positives = 3388/3393 (99%)
Query: 1 MTAWLISLMSIEVLLLAVRHLSLHIEPEEGSLAGGTWITVIFDGLELGVLYPNNGSQLEI 60
MTAWLISLMSIEVLLLAVRHLSLHIEPEEGSLAGGTWITVIFDGLELGVLYPNNGSQLEI
Sbjct: 1 MTAWLISLMSIEVLLLAVRHLSLHIEPEEGSLAGGTWITVIFDGLELGVLYPNNGSQLEI 60
Query: 61 HLVNVNMVVPALRSVPCDVFPVFLDLPVVTCRTRSVLSEAHEGLYFLEAYFGGQLVSSPN 120
HLVNVNMVVPALRSVPCDVFPVFLDLPVVTCRTRSVLSEAHEGLYFLEAYFGGQLVSSPN
Sbjct: 61 HLVNVNMVVPALRSVPCDVFPVFLDLPVVTCRTRSVLSEAHEGLYFLEAYFGGQLVSSPN 120
Query: 121 PGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLETFDFDAEYIDSPVIL 180
PGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLETFDFDAEYIDSPVIL
Sbjct: 121 PGPRDSCTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLETFDFDAEYIDSPVIL 180
Query: 181 EAQGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCHVEGDYIGSQNVSFSVFNKGKSMVH 240
EAQGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCHVEGDYIGSQNVSFSVFNKGKSMVH
Sbjct: 181 EAQGDKWVTPCSLINRQMGSCYPIQEDHGLGTLQCHVEGDYIGSQNVSFSVFNKGKSMVH 240
Query: 241 KKAWLISAKQDLFLYQTHSEILSVFPETGSLGGRTNITITGDFFDNSAQVTIAGIPCDIR 300
KKAWLISAKQDLFLYQTHSEILSVFPETGSLGGRTNITITGDFFDNSAQVTIAGIPCDIR
Sbjct: 241 KKAWLISAKQDLFLYQTHSEILSVFPETGSLGGRTNITITGDFFDNSAQVTIAGIPCDIR 300
Query: 301 HVSPRKIECTTRAPGKDVRLTTPQPGNRGLLFEVGDAVEGLELTEATPGYRWQIVPNASS 360
HVSPRKIECTTRAPGKDVRLTTPQPGNRGLLFEVGDAVEGLELTEATPGYRWQIVPNASS
Sbjct: 301 HVSPRKIECTTRAPGKDVRLTTPQPGNRGLLFEVGDAVEGLELTEATPGYRWQIVPNASS 360
Query: 361 PFGFWSQEGQPFRARLSGFFVAPETNNYTFWIQADSQASLHFSWSEEPRTKVKVASISVG 420
PFGFWSQEGQPFRARLSGFFVAPETNNYTFWIQADSQASLHFSWSEEPRTKVKVASISVG
Sbjct: 361 PFGFWSQEGQPFRARLSGFFVAPETNNYTFWIQADSQASLHFSWSEEPRTKVKVASISVG 420
Query: 421 TADWFDSWEQNRDEGTWQQKTPKLELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNP 480
TADWFDSWEQNRDEGTWQQKTPKLELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNP
Sbjct: 421 TADWFDSWEQNRDEGTWQQKTPKLELLGGAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNP 480
Query: 481 DVVTTYLREKHQIRVRAQRLPEVQVLNVSGRGNFFLTWDNVSSQPIPANATAHLIQTTIE 540
DVVTTYLREKHQIRVRAQRLPEVQVLNVSGRGNFFLTWDNVSSQPIPANATAHLIQTTIE
Sbjct: 481 DVVTTYLREKHQIRVRAQRLPEVQVLNVSGRGNFFLTWDNVSSQPIPANATAHLIQTTIE 540
Query: 541 ELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPA 600
ELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPA
Sbjct: 541 ELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGDLTSGTEPFCGRFSLRQPRHLVLTPPA 600
Query: 601 AQKGYRLDQYTHLCLAYKGHMNKILKMIVSFTIGFQNMVKNTTCDWSLTRTSPESWQFDC 660
AQKGYRLDQYTHLCLAYKGHMNKILKMIVSFTIGFQNMVKNTTCDWSLTRTSPESWQFDC
Sbjct: 601 AQKGYRLDQYTHLCLAYKGHMNKILKMIVSFTIGFQNMVKNTTCDWSLTRTSPESWQFDC 660
Query: 661 TDLWETCVRCFGDLQPPPANSPVLVHQINLLPLAQETGLFYVDEIIIADTNVTVSQADSG 720
TDLWETCVRCFGDLQPPPANSPVLVHQINLLPLAQETGLFYVDEIIIADTNVTVSQADSG
Sbjct: 661 TDLWETCVRCFGDLQPPPANSPVLVHQINLLPLAQETGLFYVDEIIIADTNVTVSQADSG 720
Query: 721 TARPGGNLVESVSVVGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEEGSGLVLVTTQR 780
TARPGGNLVESVSVVGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEEGSGLVLVTTQR
Sbjct: 721 TARPGGNLVESVSVVGSPPVYSVTSWLAGCGTELPLITARSVPTEGTEEGSGLVLVTTQR 780
Query: 781 RQRTSPPLGGHFRIQLPNTVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDL 840
RQRTSPPLGGHFRIQLPNTVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDL
Sbjct: 781 RQRTSPPLGGHFRIQLPNTVISDVPVQISAHHLHQLLQNNADDFTSRYLNASDFTVKEDL 840
Query: 841 YTCYEHVWTLSWSTQIGDLPNFIRVSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATA 900
YTCYEHVWTLSWSTQIGDLPNFIRVSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATA
Sbjct: 841 YTCYEHVWTLSWSTQIGDLPNFIRVSDENLTGVNPAAATRVVYDGGVFLGPIFGDMLATA 900
Query: 901 NQHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDGDINLMIYITGTGFSGDSQ 960
NQHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDGDINLMIYITGTGFSGDSQ
Sbjct: 901 NQHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDGDINLMIYITGTGFSGDSQ 960
Query: 961 FLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISATGEDLFLNVKPR 1020
FLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISATGEDLFLNVKPR
Sbjct: 961 FLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISATGEDLFLNVKPR 1020
Query: 1021 LDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPRGKDG 1080
LDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPRGKDG
Sbjct: 1021 LDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQCKVPPRGKDG 1080
Query: 1081 RIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLD 1140
RIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLD
Sbjct: 1081 RIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLD 1140
Query: 1141 VEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFS 1200
VEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFS
Sbjct: 1141 VEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFS 1200
Query: 1201 IEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQIPDA 1260
IEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQIPDA
Sbjct: 1201 IEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQIPDA 1260
Query: 1261 GAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEITNSSLSLHVG 1320
GAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEITNSSLSLHVG
Sbjct: 1261 GAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEITNSSLSLHVG 1320
Query: 1321 GSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSV 1380
GSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSV
Sbjct: 1321 GSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSV 1380
Query: 1381 VLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDHT 1440
VLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDHT
Sbjct: 1381 VLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDHT 1440
Query: 1441 ILCQVSLEGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLT 1500
ILCQVSLEGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLT
Sbjct: 1441 ILCQVSLEGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLT 1500
Query: 1501 TVLIRGQRLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLAPGPHYLSVFYTRNGYA 1560
TVLIRGQRLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLAPGPHYLSVFYTRNGYA
Sbjct: 1501 TVLIRGQRLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLAPGPHYLSVFYTRNGYA 1560
Query: 1561 CSGNVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGA 1620
CSGNVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGA
Sbjct: 1561 CSGNVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGA 1620
Query: 1621 ELIRCIVPTGNGSVALEIEVDGLWYHIGVIGYNKAFTPELISISQSDDILTFAVAQISGA 1680
ELIRCIVPTGNGSVALEIEVDGLWYHIGVIGYNKAFTPELISISQSDDILTFAVAQISGA
Sbjct: 1621 ELIRCIVPTGNGSVALEIEVDGLWYHIGVIGYNKAFTPELISISQSDDILTFAVAQISGA 1680
Query: 1681 ANIDIFIGMSPCVGVSGNHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITA 1740
ANIDIFIGMSPCVGVSGNHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITA
Sbjct: 1681 ANIDIFIGMSPCVGVSGNHTVLQCVVPSLPAGEYHVRGYDCIRGWASSALVFTSRVIITA 1740
Query: 1741 VTENFGCLGGRLVHVFGAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLC 1800
VTENFGCLGGRLVHVFGAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLC
Sbjct: 1741 VTENFGCLGGRLVHVFGAGFSPGNVSAAVCGAPCRVLANATVSAFSCLVLPLDVSLAFLC 1800
Query: 1801 GLKREEDSCEAARHTYVQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAESMFPS 1860
GLKREEDSCEAARHTYVQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAESMFPS
Sbjct: 1801 GLKREEDSCEAARHTYVQCDLTVAMATEQLLESWPYLYICEESSQCLFVPDHWAESMFPS 1860
Query: 1861 FSGLFISPKLERDEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNF 1920
FSGLFISPKLERDEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNF
Sbjct: 1861 FSGLFISPKLERDEVLIYNSSCNITMETEAEMECETPNQPITVKITEIRKRWGQNTQGNF 1920
Query: 1921 SLQFCRRWSRTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPGP 1980
SLQFCRRWSRTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPGP
Sbjct: 1921 SLQFCRRWSRTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPGP 1980
Query: 1981 IELRAHAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLH 2040
IELRAHAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLH
Sbjct: 1981 IELRAHAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLH 2040
Query: 2041 GSLPEVIVTCLRATAHALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQ 2100
GSLPEVIVTCLRATAHALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQ
Sbjct: 2041 GSLPEVIVTCLRATAHALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQ 2100
Query: 2101 DTDLYLKSPLRYSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEAN 2160
DTDLYLKSPLRYSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEAN
Sbjct: 2101 DTDLYLKSPLRYSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEAN 2160
Query: 2161 APEGNLQHCLYSMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSL 2220
APEGNLQHCLYSMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSL
Sbjct: 2161 APEGNLQHCLYSMSEKMLGSRDMGARVIVQSFPEEPSQVQLKGVQFQVLGQAFHKHLSSL 2220
Query: 2221 TLVGAMRESFIQGCTVRNSFSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISW 2280
TLVGAMRESFIQGCTVRNSFSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISW
Sbjct: 2221 TLVGAMRESFIQGCTVRNSFSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISW 2280
Query: 2281 EAIHGRKDDWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAG 2340
EAIHGRKDDWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAG
Sbjct: 2281 EAIHGRKDDWSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAG 2340
Query: 2341 YGYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWES 2400
YGYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWES
Sbjct: 2341 YGYFFHLMTNQTSQAPLLSFTQNIAHSCTRYGLFVYPKFQPPWDNVTGTTLFQSFTVWES 2400
Query: 2401 AGGAQIFRSSNLRLKNFKVYSCRDFGIDVLESDANTSVTDSLLLGHFAHKGSLCMSSGIK 2460
AGGAQIFRSSNLRLKNFKVYSCRDFGIDVLESDANTSVTDSLLLGHFAHKGSLCMSSGIK
Sbjct: 2401 AGGAQIFRSSNLRLKNFKVYSCRDFGIDVLESDANTSVTDSLLLGHFAHKGSLCMSSGIK 2460
Query: 2461 TPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQLKFTNSSNLVAFPFPH 2520
TPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQLKFTNSSNLVAFPFPH
Sbjct: 2461 TPKRWELMVSNTTFVNFDLINCVAIRTCSDCSQGQGGFTVKTSQLKFTNSSNLVAFPFPH 2520
Query: 2521 AAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMSIGLAN 2580
AAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMSIGLAN
Sbjct: 2521 AAILEDLDGSLSGKNRSHILASMETLSASCLVNSSFGRVVHGSACGGGVLFHRMSIGLAN 2580
Query: 2581 TPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSLQYSA 2640
TPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSLQYSA
Sbjct: 2581 TPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSLQYSA 2640
Query: 2641 TFDNFAPGNYLLLVHTDLPPYPDILLRCGSRVGLSFPFLPSPGQNQGCDWFFNSQLRQLT 2700
TFDNFAPGNYLLLVHTDLPPYPDILLRCGSRVGLSFPFLPSPGQNQGCDWFFNSQLRQLT
Sbjct: 2641 TFDNFAPGNYLLLVHTDLPPYPDILLRCGSRVGLSFPFLPSPGQNQGCDWFFNSQLRQLT 2700
Query: 2701 YLVSGEGQVQVILRVKEGMPPTISASTSAPESALKWSLPETWQGVEEGWGGYNNTIPGPG 2760
YLVSGEGQVQVILRVKEGMPPTISASTSAPESALKWSLPETWQGVEEGWGGYNNTIPGPG
Sbjct: 2701 YLVSGEGQVQVILRVKEGMPPTISASTSAPESALKWSLPETWQGVEEGWGGYNNTIPGPG 2760
Query: 2761 DDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVIAGGELKVGTLENPL 2820
DDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVIAGGELKVGTLENPL
Sbjct: 2761 DDVLILPNRTVLVDTDLPFFKGLYVMGTLDFPVDRSNVLSVACMVIAGGELKVGTLENPL 2820
Query: 2821 EKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVHLYSAYPKNSWTHLGADIASGNE 2880
EKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVHLYSAYPKNSWTHLGADIASGNE
Sbjct: 2821 EKEQKLLILLRASEGVFCDRMNGIHIDPGTIGVYGKVHLYSAYPKNSWTHLGADIASGNE 2880
Query: 2881 RIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIYERLKHRHIGSVHVTED 2940
RIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIYERLKHRHIGSVHVTED
Sbjct: 2881 RIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHHVRIYERLKHRHIGSVHVTED 2940
Query: 2941 GRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSGVLQLLNVEIQNFGSPL 3000
GRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSGVLQLLNVEIQNFGSPL
Sbjct: 2941 GRHIRLAAEVGLLTRNIQIQPDVSCRGRLFVGSFRKSSREEFSGVLQLLNVEIQNFGSPL 3000
Query: 3001 YSSVEFSNVSAGSWIISSTLHQSCGGGIHAAASHGVLLNDNIVFGTAGHGIDLEGQAYTV 3060
YSSVEFSNVSAGSWIISSTLHQSCGGGIHAAASHGVLLNDNIVFGTAGHGIDLEGQAYTV
Sbjct: 3001 YSSVEFSNVSAGSWIISSTLHQSCGGGIHAAASHGVLLNDNIVFGTAGHGIDLEGQAYTV 3060
Query: 3061 TNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHKCSSCELLWSD 3120
TNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHKCSSCELLWSD
Sbjct: 3061 TNNLVVLMTQPAWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHKCSSCELLWSD 3120
Query: 3121 NVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGLL 3180
NVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGLL
Sbjct: 3121 NVAHSSLHGLHLYKESGLDNCTRISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGLL 3180
Query: 3181 AVVYVFSAPQNSVKKVQIVLRNSVIVATSSSFDCIQDKVKPHSANLTSTDRAPSNPRGGR 3240
AVVYVFSAPQNSVKKVQIVLRNSVIVATSSSFDCIQDKVKPHSANLTSTDRAPSNPRGGR
Sbjct: 3181 AVVYVFSAPQNSVKKVQIVLRNSVIVATSSSFDCIQDKVKPHSANLTSTDRAPSNPRGGR 3240
Query: 3241 IGILWPVFTSEPNQWPQEPWHKVRNDHSISGIMKLQDVTFSSFVKSCYSDDLDVCILPNA 3300
IGILWPVFTSEPNQWPQEPWHKVRNDHSISGIMKLQDVTFSSFVKSCYSDDLDVCILPNA
Sbjct: 3241 IGILWPVFTSEPNQWPQEPWHKVRNDHSISGIMKLQDVTFSSFVKSCYSDDLDVCILPNA 3300
Query: 3301 ENSGIMHPITAERTRMLKIKDKNKFYFPSLQPRKDLGKVVCPELDCASPRKYLFKDLDGR 3360
ENSGIMHPITAERTRMLKIKDKNKFYFPSLQPRKDLGKVVCPELDCASPRKYLFKDLDGR
Sbjct: 3301 ENSGIMHPITAERTRMLKIKDKNKFYFPSLQPRKDLGKVVCPELDCASPRKYLFKDLDGR 3360
Query: 3361 ALGLPPPVSVFPKTEAEWTASFFNAVTTEQALK 3393
ALGLPPPVSVFPKTEAEWTASFFNA T + K
Sbjct: 3361 ALGLPPPVSVFPKTEAEWTASFFNAGTFREEQK 3393
>gi|126116589 fibrocystin L [Homo sapiens]
Length = 4243
Score = 694 bits (1790), Expect = 0.0
Identities = 606/2223 (27%), Positives = 1007/2223 (45%), Gaps = 233/2223 (10%)
Query: 1303 VTAMQGEITNSSLSLHVGGSNLS-NSVILLGNLNCDVETQSFQGNVSLSGCSI-PLHSLE 1360
+T G + + G SNL + + +G+ C VE +S + +++ C I P +S++
Sbjct: 1571 ITPSTGTVNELITIIGHGFSNLPWANKVTIGSYPCVVE-ESSEDSIT---CHIDPQNSMD 1626
Query: 1361 AGI---YPLQVRQKQMGFANMSVVL-QQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNS 1416
GI L V +S ++F ++P I + P+ GS G T +T++G
Sbjct: 1627 VGIRETVTLTVYNLGTAINTLSNEFDRRFVLLPNIDLVLPNAGSTTGMTSVTIKGSGFAV 1686
Query: 1417 RRRSVRVDLSGPFTCVILSLGDHTILCQVSLEGDPLPGASFSLNVTVLVNGLTSECQGNC 1476
V+V L G F C +LS+ I C+ S P A ++V +L++G+ ++CQGNC
Sbjct: 1687 SSAGVKV-LMGHFPCKVLSVNYTAIECETS------PAAQQLVDVDLLIHGVPAQCQGNC 1739
Query: 1477 TLFIREEASPVMDALSTNTSGSLTTVLIRGQRLATTADEPMVFVDDQLPCNVTFFNASHV 1536
T E +P + + N+ VLI G+ L T ++ VF+ +Q N +++
Sbjct: 1740 TFSYLESITPYITGVFPNSVIGSVKVLIEGEGLGTVLEDIAVFIGNQ-QFRAIEVNENNI 1798
Query: 1537 VCQTRDLAPGPHYLSVFYTRNGYACSGNVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGT 1596
L G H +SV G A GN++ P V P + S+ GG+ L I G
Sbjct: 1799 TALVTPLPVGHHSVSVVVGSKGLAL-GNLT---VSSPPVASLSPTSGSIGGGTTLVITGN 1854
Query: 1597 GLRGQNTTSVYIDQQTCLTVNIGAELIRCIVPTGN-GSVALEIEVDGLWYHIGVIGYNKA 1655
G NTT V I + C ++I + C P G G V ++I V+ + Y + Y
Sbjct: 1855 GFYPGNTT-VTIGDEPCQIISINPNEVYCRTPAGTTGMVDVKIFVNTIAYPPLLFTYALE 1913
Query: 1656 FTPELISISQSDDILTFAVAQISGA------ANIDIFIGMSPCVGVSGNHTVLQCVVPSL 1709
TP L I S + +I+G+ I + I C N +V+QC+V
Sbjct: 1914 DTPFLRGIIPSRGPPGTEI-EITGSNFGFEILEISVMINNIQCNVTMANDSVVQCIVGDH 1972
Query: 1710 PAGEYHVRGYDCIRGWASSALVFTSRVIITAVTENFGCLGG-RLVHVFGAGFSPGNVSAA 1768
G + V + +G A S +VF + I + + G GG + + V G GF+P N
Sbjct: 1973 AGGTFPVMMHHKTKGSAMSTVVFEYPLNIQNINPSQGSFGGGQTMTVTGTGFNPQNSIIL 2032
Query: 1769 VCGAPCRVLANATVSAFSCLVLPLDVSLAFLCGLKREEDS-CEAARHTYVQCDLTVAMAT 1827
VCG+ C + + S ++ L LC + + E A C+++V
Sbjct: 2033 VCGSECAI--DRLRSDYTTL----------LCEIPSNNGTGAEQA------CEVSVVNGK 2074
Query: 1828 EQLLESWPYLYICEESSQCLFVPDH---WAESMFPSFSGLFISPKLERDEVLIYNSSCNI 1884
+ P+ Y + V A + G S +E + I + C++
Sbjct: 2075 DLSQSMTPFTYAVSLTPLITAVSPKRGSTAGGTRLTVVGSGFSENMEDVHITIAEAKCDV 2134
Query: 1885 TMETEAEMECETPNQ------PITVKITEIRKRWGQNTQGNFSLQFCRRWSRTHSWFPER 1938
+ + C T P+ V I + G N + WS SW +
Sbjct: 2135 EYSNKTHIICMTDAHTLSGWAPVCVHIRGV----GMAKLDNADFLYVDAWSSNFSWGGKS 2190
Query: 1939 LPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPGPIELRAHAILVSDGGELRI 1998
P++G V + GQ +LLD +T IL +L I+GG LIF IEL+A IL++DGG L+I
Sbjct: 2191 PPEEGSLVVITKGQTILLDQSTPILKMLLIQGGTLIF-DEADIELQAENILITDGGVLQI 2249
Query: 1999 GSEDKPFQGRAQITLYGSSYSTPFFPYGVKFLAVRNGTLSLHGSLPEVIVTCLRATAHAL 2058
G+E PFQ +A ITL+G S YG K LAVR G L LHG V T L TA A
Sbjct: 2250 GTETSPFQHKAVITLHGHLRSPELPVYGAKTLAVREGILDLHGVPVPVTWTRLAHTAKAG 2309
Query: 2059 DTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETV--QDTDLYLKSPLRYSH-N 2115
+ +L L++AV W PGD +VI S TG + ++ E +T+ +V ++ L +PL Y+H
Sbjct: 2310 ERILILQEAVTWKPGDNIVIAS-TGHRHSQGENEKMTIASVSADGINITLSNPLNYTHLG 2368
Query: 2116 FTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEA-NAPEGNLQHCLYSMS 2174
T G +A V +L+R+I I+G+ E + +C + + E Q CL
Sbjct: 2369 ITVTLPDGTLFEARAEVGILTRNILIRGSDNVEWNNKIPACPDGFDTGEFATQTCLQGKF 2428
Query: 2175 EKMLGSRDMGARVIVQSFPEEPSQV--QLKGVQFQVLGQAFH--KHLSSLTLVGAMR-ES 2229
+ +GS G V+ + + V +++ V+ GQAF ++ L+G ++ +S
Sbjct: 2429 GEEIGSDQFGGCVMFHAPVPGANMVTGRIEYVEVFHAGQAFRLGRYPIHWHLLGDLQFKS 2488
Query: 2230 FIQGCTVRNSFSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDD 2289
+++GC + +++R +++ T L V+ N+ Y+I G A + +D
Sbjct: 2489 YVRGCAIHQAYNRAVTIHNTHHLLVERNIIYDIKGGAFFI------------------ED 2530
Query: 2290 WSGHGNIIRNNVIIQVSGAEGLSNPEMLTPSGIYICSPTNVIEGNRVCGAGYGYFFHLMT 2349
HGNI++ N+ + V + L N + +TP+ ++ +P N I N V G + F++ M
Sbjct: 2531 GIEHGNILQYNLAVFVQQSTSLLNDD-VTPAAFWVTNPNNTIRHNAVAGGTHFGFWYRMN 2589
Query: 2350 NQ-----------TSQAPLLSFTQNIAHSCTRYGLFVYPKFQPP-----WDNVTGTTLFQ 2393
N + PL F N HS +G++++ ++ P V +F
Sbjct: 2590 NHPDGPSYDRNICQKRVPLGEFFNNTVHSQGWFGMWIFEEYFPMQTGSCTSTVPAPAIFN 2649
Query: 2394 SFTVWESAGGAQIFRSSNLRLKNFKVYSCRDFGIDVLE---------SDANTSV-TDSLL 2443
S T W GA+ L+ NF + + + GI+ + N +V ++ +
Sbjct: 2650 SLTTWNCQKGAEWVNGGALQFHNFVMVNNYEAGIETKRILAPYVGGWGETNGAVIKNAKI 2709
Query: 2444 LGHFAHKG---SLCMSSGIKTPKRWELMVSNTTFVNFDLINCVAIRTCS---DCSQGQGG 2497
+GH G + C + G+ P L VS+ F+NFD NCVA+ S C+ GG
Sbjct: 2710 VGHLDELGMGSAFCTAKGLVLPFSEGLTVSSVHFMNFDRPNCVALGVTSISGVCNDRCGG 2769
Query: 2498 FTVKTSQLKFTNSSNLVAFPFPHAAILEDLDGSLSGKNRSHILASMETLSAS-CLVNSSF 2556
++ K ++++++ N F + H ++ D+DGSL+G ++ L S C + +
Sbjct: 2770 WSAKFVDVQYSHTPNKAGFRWEHEMVMIDVDGSLTGHKGHTVIPHSSLLDPSHCTQEAEW 2829
Query: 2557 GRVVHGSACGGGVLFHRMSIGLANTPE----VSYDLTMTDSRNKTTTVNYVRDTLSNPRG 2612
GS C V FHR++ N P + D+ ++DS T+ + + + L++ G
Sbjct: 2830 SIGFPGSVCDASVSFHRLAF---NQPSPVSLLEKDVVLSDSFG-TSIIPFQKKRLTHMSG 2885
Query: 2613 WMALLLDQETYSLQSENLWINRSLQYSATFDNFAPGNYLLLVHTDLPPYPDILLRCGSRV 2672
WMAL+ + + + + ++ Y++TF F +Y+++ H + PD+ R
Sbjct: 2886 WMALIPNANHINWYFKGVDHITNISYTSTFYGFKEEDYVIISH-NFTQNPDMFNIIDMRN 2944
Query: 2673 GLSFPFLPSPGQNQGCDWFFNSQLRQLTYLVSGEGQVQVILRVKEGMPPTIS-------- 2724
G S P + +N DW + L YLVSG + + + P +
Sbjct: 2945 GSSNPLNWNTSKNG--DWHLEANTSTLYYLVSGRNDLHQSQLISGNLDPDVKDVVINFQA 3002
Query: 2725 ------------------ASTSAPESALKWSLPETWQGVEEGWGGYNNTIPGPGDDVLIL 2766
P + WS WQ E N T+P PG +V+I
Sbjct: 3003 YCCILQDCFPVHPPSRKPIPKKRPATYNLWSNDSFWQSSREN----NYTVPHPGANVIIP 3058
Query: 2767 PNRTVLVDTDLPFFKGLYVMGTLDFPVDRSN-----------VLSVACMVIAGGELKVGT 2815
++ D D+P + L + G L+ D+ N VL+ + + GG L G
Sbjct: 3059 EGTWIVADIDMPSMERLIIWGVLELE-DKYNVGAAESSYREVVLNATYISLQGGRLIGGW 3117
Query: 2816 LENPLEKEQKLLILLRASEGVFCDRM-NGIHIDPGTIGVYGKVHLYSAYPKNSWTHLGAD 2874
+NP + + K I+LR + + G + +GV+G++ L+ T L
Sbjct: 3118 EDNPFKGDLK--IVLRGNHTTQDWALPEGPNQGAKVLGVFGELDLHGIPHSIYKTKLSET 3175
Query: 2875 IASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTVKEVKGHH--VRIYERLKHRHI 2932
+G++ + + DAVDW+ ++IV++++SY+ H+ E ++ ++ H + + + L + H
Sbjct: 3176 AFAGSKVLSLMDAVDWQEGEEIVITTTSYDFHQTETRSIVKILHDHKILILNDSLSYTHF 3235
Query: 2933 G-SVHVTEDGRHIRLAAEVGLLTRNIQI-------QPDVSCRGRLFVGSFRKSSREEFSG 2984
HV G LAA+VG+L+RNI+I + S R+ VGSF ++ F G
Sbjct: 3236 AEKYHVPGTGESYTLAADVGILSRNIKIVGEDYPGWSEDSFGARVLVGSFTENMM-TFKG 3294
Query: 2985 VLQLLNVEIQNFG--------SPLYSSVEFSNVS-----AGSWIISSTLHQSCGGGIHAA 3031
++ NVE + G P Y +V F N+ S+I H I
Sbjct: 3295 NARISNVEFYHSGQEGFRDSTDPRY-AVTFLNLGQIQEHGSSYIRGCAFHHGFSPAIGVF 3353
Query: 3032 ASHGVLLNDNIVFGTAGHGIDLEGQAYTVTNNLVVLMTQPAW--------STIWVAGIKV 3083
+ G+ ++DNI+ T G GI + G A V NL+ L P ST+W A I++
Sbjct: 3354 GTDGLDIDDNIIHFTVGEGIRIWGNANRVRGNLIALSVWPGTYQNRKDLSSTLWHAAIEI 3413
Query: 3084 NQVKDINLHGNVVAGSERLGFHIRGHKCS---SCELLWSDNVAHSSLHGLHLYKESGLDN 3140
N+ + L NVVAG R G+ I G C + W DN AH L+G+++ + GL
Sbjct: 3414 NRGTNTVLQNNVVAGFGRAGYRIDGEPCPGQFNPVEKWFDNEAHGGLYGIYM-NQDGLPG 3472
Query: 3141 CTRISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGLLAVVYVFSAPQNSVKKVQIVL 3200
C+ I GF + +DYG SV I N+TLVDN + + ++Y+ +A + + + +
Sbjct: 3473 CSLIQGFTIWTCWDYGIYFQTTESVHIYNVTLVDNGMAIFPMIYMPAAISHKISSKNVQI 3532
Query: 3201 RNSVIVATSSSFDCIQDKVKPHSAN--LTSTDRAPSNPRGGRIGILWPVFTSEPNQWPQE 3258
++S+IV +S F+C D + N LT+ R+P +P GGR GI WP F S N P++
Sbjct: 3533 KSSLIVGSSPGFNC-SDVLTNDDPNIELTAAHRSPRSPSGGRSGICWPTFASAHNMAPRK 3591
Query: 3259 PWHKVRNDHSISGIMKLQDVTFSSFVKSCYSDDLDVCILPNAENSGIMHPITAERTRMLK 3318
P + + ++ISG++ + TF F C S + +V + N N + HPI + +++
Sbjct: 3592 PHAGIMSYNAISGLLDISGSTFVGFKNVC-SGETNVIFITNPLNEDLQHPIHVKNIKLVD 3650
Query: 3319 IKDKNKFYFPSLQPRKDLGKV---VCPELDCASPRKYLFKDLDGRALGLPPPVSVFPKTE 3375
+++K + R D+ KV C ++ C + RK +D+DG LG SV P+ E
Sbjct: 3651 TTEQSKIFI----HRPDISKVNPSDCVDMVCDAKRKSFLRDIDGSFLG--NAGSVIPQAE 3704
Query: 3376 AEW 3378
EW
Sbjct: 3705 YEW 3707
Score = 257 bits (656), Expect = 2e-67
Identities = 322/1329 (24%), Positives = 532/1329 (40%), Gaps = 195/1329 (14%)
Query: 514 FFLTWDNVSSQPIPANATAHLIQTTIEELLAVKCKLEPLWSNILLRLGFERGPEVSN--- 570
F L WD ++S+P+ ++ Q +EE+++ KC P +N FE G V
Sbjct: 637 FTLNWDGIASKPLTLWSSEAEFQGAVEEMVSTKCP--PQIAN------FEEGFVVKYFRD 688
Query: 571 ----------SDGDLTSGTEPFCGRFSLRQPRHLVLTPPAAQKGYR-------LDQYTHL 613
+ G T+ T+ +CGR+SL+ P VL A K R L Y L
Sbjct: 689 YETDFNLEHINRGQKTAETDAYCGRYSLKNPA--VLFDSADVKPNRRPYGDILLFPYNQL 746
Query: 614 CLAYKGHMNKILKMIVSFTIGFQNMVKNTTCDWSLTRTSPESWQFDCTDLWETCVRCFGD 673
CLAYKG + + + + + ++T ++ +W + C DL +
Sbjct: 747 CLAYKGFLANYIGLKFQYQDN-SKITRSTDTQFTYNFAYGNNWTYTCIDLLDL------- 798
Query: 674 LQPPPANSPVLVHQINLLPLAQETGLFYVDEIIIADTNVTVSQADSGTARP------GGN 727
++ + V + +I+L A E+ FYVD + I T+ T+S D R G
Sbjct: 799 VRTKYTGTNVSLQRISLHK-ASESQSFYVDVVYIGHTS-TISTLDEMPKRRLPALANKGI 856
Query: 728 LVESVSV----VGSPPV---YSVTSWLAGCGTELPLITAR--SVPTEGTEEG-------- 770
+E V P + YSVT C +P++ + T TE
Sbjct: 857 FLEHFQVNQTKTNGPTMTNQYSVTMTSYNCSYNIPMMAVSFGQIITHETENEFVYRGNNW 916
Query: 771 SGLVLVTTQRRQRTSPPLGGHFRIQLPNTVISDVPVQISAHHLHQLLQNNADDFTSRYLN 830
G + QR Q SPPL G F IQ ++ +P +SA L LQ+
Sbjct: 917 PGESKIHIQRIQAASPPLSGSFDIQAYGHILKGLPAAVSAADLQFALQSLE--------G 968
Query: 831 ASDFTVKEDLYTCYEHVWTLSWSTQIGDLPNFIRVSDENLTGVNPAAATRVVYDGGVFLG 890
+V + TC + W + W + G N ++++D N+ G + +GG+F
Sbjct: 969 MGRISVTRE-GTCAGYAWNIKWRSTCGK-QNLLQINDSNIIGEKANMTVTRIKEGGLFRQ 1026
Query: 891 PIFGDMLATANQHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVWYSIDG-DINLMIY 949
+ GD+L T +Q QV V VN +PA C G C F + TP V ++ S + ++
Sbjct: 1027 HVLGDLLRTPSQQPQVEVYVNGIPAKCSGDCGFTWDSNITPLVLAISPSQGSYEEGTILT 1086
Query: 950 ITGTGFSGDSQFLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISAT 1009
I G+GFS S + V+V C ++ ++ + CQ G + + + GLA +
Sbjct: 1087 IVGSGFS-PSSAVTVSVGPVGCSLLSVDEKELKCQILNGSAGHAPVAVSMADVGLAQNVG 1145
Query: 1010 GEDLFLNVKPRLDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRI 1069
GE+ + + ++ + P + GG T+ G S +L G+ +C NV + +RI
Sbjct: 1146 GEEFYFVYQSQISHIWPDSGSIAGGTLLTLSGFGFNENSKVLVGNETC--NVIEGDLNRI 1203
Query: 1070 QCKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIG 1129
C+ P K V+++V + A AF+Y P+I S + I G L I
Sbjct: 1204 TCRTPK--KTEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPKVRTILGEVNLTIK 1261
Query: 1130 VARLMNYTDLDVEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSIN--GVSIHSQG 1187
N ++ V+V + + + LP L G H I V + G +
Sbjct: 1262 GYNFGNELTQNMAVYVGGKTCQILHWNFTDIRCLLPKLSPGKHDIYVEVRNWGFASTRDK 1321
Query: 1188 VDLHIQYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASI 1247
++ IQY+ EV S+ P GSL GGT ++I G GFS PA VL+G+ C++ + +E I
Sbjct: 1322 LNSSIQYVLEVTSMFPQRGSLFGGTEITIRGFGFSTIPAENTVLLGSIPCNVTSSSENVI 1381
Query: 1248 WC---ETLPAPQIPDAGAPTVPAAVEVWA-------------------------GNRFFA 1279
C T +I + G +V W+ G R F+
Sbjct: 1382 KCILHSTGNIFRITNNGKDSVHGLGYAWSPPVLNVSVGDTVAWHWQTHPFLRGIGYRIFS 1441
Query: 1280 RGPSPSLV--GKGFT----------FMYEAAA-------------------TPVVTAMQG 1308
S++ GKGFT F Y+ + V+ +
Sbjct: 1442 VSSPGSVIYDGKGFTSGRQKSTSGSFSYQFTSPGIHYYSSGYVDEAHSIFLQGVINVLPA 1501
Query: 1309 EITNSSLSLHVGGSNLSNSVILLGNLNCDVETQSFQGNVSLSGC--SIPLHSLEAGIYPL 1366
E + L L VG S + + NL+ S++GC + PL SL
Sbjct: 1502 ETRHIPLHLFVGRSEATYAYGGPENLHL---------GSSVAGCLATEPLCSLN----NT 1548
Query: 1367 QVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLS 1426
+V+ + +S P I I PS G+ ++T+ G ++ + +V +
Sbjct: 1549 RVKNSKRLLFEVSSCFS-----PSISNITPSTGTV--NELITIIGHGFSNLPWANKVTI- 1600
Query: 1427 GPFTCVILSLGDHTILCQVSLEGDPLPGASFSLNVTV-----LVNGLTSECQGNCTLFIR 1481
G + CV+ + +I C + + G ++ +TV +N L++E L
Sbjct: 1601 GSYPCVVEESSEDSITCHIDPQNSMDVGIRETVTLTVYNLGTAINTLSNEFDRRFVLL-- 1658
Query: 1482 EEASPVMDALSTNTSGS--LTTVLIRGQRLATTADEPMVFVDDQLPCNVTFFNASHVVCQ 1539
P +D + N + +T+V I+G A ++ V + PC V N + + C+
Sbjct: 1659 ----PNIDLVLPNAGSTTGMTSVTIKGSGFAVSSAGVKVLM-GHFPCKVLSVNYTAIECE 1713
Query: 1540 TRDLAPGPHYLSVFYTRNGYACSGNVSRHFY--IMPQVFHYFPKNFSLHGGSLLTIEGTG 1597
T A + + C GN + + I P + FP S+ G + IEG G
Sbjct: 1714 TSPAAQQLVDVDLLIHGVPAQCQGNCTFSYLESITPYITGVFPN--SVIGSVKVLIEGEG 1771
Query: 1598 L-RGQNTTSVYIDQQTCLTVNIGAELIRCIV---PTGNGSVALEIEVDGLWYHIGVIGYN 1653
L +V+I Q + + I +V P G+ SV++ + GL +G
Sbjct: 1772 LGTVLEDIAVFIGNQQFRAIEVNENNITALVTPLPVGHHSVSVVVGSKGL-----ALGNL 1826
Query: 1654 KAFTPELISISQSDDIL---TFAVAQISG--AANIDIFIGMSPCVGVSGNHTVLQCVVPS 1708
+P + S+S + + T V +G N + IG PC +S N + C P+
Sbjct: 1827 TVSSPPVASLSPTSGSIGGGTTLVITGNGFYPGNTTVTIGDEPCQIISINPNEVYCRTPA 1886
Query: 1709 LPAGEYHVR 1717
G V+
Sbjct: 1887 GTTGMVDVK 1895
Score = 188 bits (477), Expect = 9e-47
Identities = 156/540 (28%), Positives = 244/540 (45%), Gaps = 64/540 (11%)
Query: 4 WLISLMSIEVLLLAVRHLSL----------HIEPEEGSLAGGTWITVIFDGLELGVLYPN 53
WL+ + + LLL S I P+ GS+ G T +T+ +G +
Sbjct: 5 WLLGIWGLCGLLLCAADPSTDGSQIIPKVTEIIPKYGSINGATRLTIRGEGFSQANQFNY 64
Query: 54 NGSQLEIHLVNVNMVVPALRSVPCDVFPVFLDLPVVTCRTRSVLSEAHEGLYFLEAYFGG 113
E L N ++ + +S+ CDV +TC TR++ ++ Y + G
Sbjct: 65 GVDNAE--LGNSVQLISSFQSITCDVEKDASHSTQITCYTRAMPEDS----YTVRVSVDG 118
Query: 114 QLVSSPNP--GPRDS--CTFKFSKAQTPIVHQVYPPSGVPGKLIHVYGWIITGRLETFDF 169
V+ N G +S CTF +TP + + P SG PG LI + G I T
Sbjct: 119 VPVTENNTCKGHINSWECTFNAKSFRTPTIRSITPLSGTPGTLITIQGRIFT-------- 170
Query: 170 DAEYIDSPVILEAQGDK--------WVTPCSLINRQMGSCYPIQEDH---GLGTLQCHVE 218
+ S + L + G PC L+ Q + Y ++ DH +G++ C
Sbjct: 171 --DVYGSNIALSSNGKNVRILRVYIGGMPCELLIPQSDNLYGLKLDHPNGDMGSMVCKTT 228
Query: 219 GDYIGSQNVSFSVFNK-GKSMVHKKAWLISAKQDLFLYQTHSEILSVFPETGSLGGRTNI 277
G +IG NVSF + N G+S K A+ +S+ + ++QT++E+ +FP GS+ G T +
Sbjct: 229 GTFIGHHNVSFILDNDYGRSFPQKMAYFVSSLNKIAMFQTYAEVTMIFPSQGSIRGGTTL 288
Query: 278 TITGDFFDNS---AQVTIAGIPCDIRHVSPRKIECTTRAPGKDVRLTTPQPGNRGLLFEV 334
TI+G FFD + +V + G PCDI +V+ I C T P K L T PG RGL EV
Sbjct: 289 TISGRFFDQTDFPVRVLVGGEPCDILNVTENSICCKT--PPKPHILKTVYPGGRGLKLEV 346
Query: 335 GD------AVEGLELTEATPGYRWQIVPNASSPFGFWSQEGQPFRARLSGFFVAPETNNY 388
+ E LE E TPGY +++S W E F AR SGF VAP+++ Y
Sbjct: 347 WNNSRPIRLEEILEYNEKTPGYMGASWVDSASYI--WLMEQDTFVARFSGFLVAPDSDVY 404
Query: 389 TFWIQADSQASLHFSWSEEPRTKVKVASISVGTADWFDSWEQNRDEGTWQQKTPKLELLG 448
F+I+ D + +++FS + P KV++A S +F S Q D+ + L
Sbjct: 405 RFYIKGDDRYAIYFSQTGLPEDKVRIAYHSANANSYFSSPTQRSDD---------IHLQK 455
Query: 449 GAMYYLEAEHHGIAPSRGMRIGVQIHNTWLNPDVVTTYLREKHQIRVRAQRLPEVQVLNV 508
G YY+E S + +G+ + + E+ I+ ++ L EVQV+ +
Sbjct: 456 GKEYYIEILLQEYRLSAFVDVGLYQYRNVYTEQQTGDAVNEEQVIKSQSTILQEVQVITL 515
Score = 123 bits (308), Expect = 4e-27
Identities = 156/622 (25%), Positives = 262/622 (42%), Gaps = 74/622 (11%)
Query: 942 GDINLMIYITGTGFSGDSQFLQVTVNKTSCKVIFSNQTNVVCQTD---LLPVGMHR-ILM 997
G +N +I I G GFS +VT+ C V S++ ++ C D + VG+ + +
Sbjct: 1576 GTVNELITIIGHGFSNLPWANKVTIGSYPCVVEESSEDSITCHIDPQNSMDVGIRETVTL 1635
Query: 998 LVRPSGLAISATGE--DLFLNVKPRLDMVEPSRAADIGGLWATIRGS----SLEGVSLIL 1051
V G AI+ D + P +D+V P+ + G TI+GS S GV +L
Sbjct: 1636 TVYNLGTAINTLSNEFDRRFVLLPNIDLVLPNAGSTTGMTSVTIKGSGFAVSSAGVK-VL 1694
Query: 1052 FGSYSCAINVATSNSSRIQCKVPPRGKDGRIVNVTVIRGDYSAVLPR--AFTYVSSLNPV 1109
G + C V + N + I+C+ P + ++V+V ++ A F+Y+ S+ P
Sbjct: 1695 MGHFPC--KVLSVNYTAIECETSPAAQ--QLVDVDLLIHGVPAQCQGNCTFSYLESITPY 1750
Query: 1110 IVTLSRNISNIAGGETLVIGVARLMNYTDLDVEVHVQDALAPVHTQSAWGLEVALPPLPA 1169
I + N S I + L+ G D+ V + Q A ++ + + PLP
Sbjct: 1751 ITGVFPN-SVIGSVKVLIEGEGLGTVLEDIAVFIGNQQFRAIEVNEN--NITALVTPLPV 1807
Query: 1170 GLHRISVSINGVSIHSQGVDLHIQYLTE--VFSIEPCCGSLLGGTILSISGIGFSRDPAL 1227
G H +SV + S+G+ L ++ V S+ P GS+ GGT L I+G GF P
Sbjct: 1808 GHHSVSVVVG-----SKGLALGNLTVSSPPVASLSPTSGSIGGGTTLVITGNGFY--PGN 1860
Query: 1228 VWVLVGNRSCDIVNLTEASIWCETLPAPQIPDAGAPTVPAAVEVWAGNRFFARGPSPSLV 1287
V +G+ C I+++ ++C T PA + F ++
Sbjct: 1861 TTVTIGDEPCQIISINPNEVYCRT--------------PAGTTGMVDVKIFVN----TIA 1902
Query: 1288 GKGFTFMYEAAATPVVTAMQGEITNSSLSLHVGGSNLSNSV----ILLGNLNCDVETQSF 1343
F Y TP + + + + GSN + +++ N+ C+V
Sbjct: 1903 YPPLLFTYALEDTPFLRGIIPSRGPPGTEIEITGSNFGFEILEISVMINNIQCNVT---- 1958
Query: 1344 QGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACG 1403
N S+ C + H+ G +P+ + K G A +VV F I I PSQGS G
Sbjct: 1959 MANDSVVQCIVGDHA--GGTFPVMMHHKTKGSAMSTVV---FEYPLNIQNINPSQGSFGG 2013
Query: 1404 GTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDH--TILCQVSLEGDPLPGASFSLNV 1461
G +TV G N + + V S C I L T+LC++ GA + V
Sbjct: 2014 GQTMTVTGTGFNPQNSIILVCGS---ECAIDRLRSDYTTLLCEIPSNNG--TGAEQACEV 2068
Query: 1462 TVLVNGLTSECQGNCTLFIREEASPVMDALST---NTSGSLTTVLIRGQRLATTADEPMV 1518
+V VNG Q +P++ A+S +T+G T + + G + ++ +
Sbjct: 2069 SV-VNG-KDLSQSMTPFTYAVSLTPLITAVSPKRGSTAGG-TRLTVVGSGFSENMEDVHI 2125
Query: 1519 FVDDQLPCNVTFFNASHVVCQT 1540
+ + C+V + N +H++C T
Sbjct: 2126 TI-AEAKCDVEYSNKTHIICMT 2146
Score = 89.4 bits (220), Expect = 6e-17
Identities = 123/544 (22%), Positives = 214/544 (39%), Gaps = 71/544 (13%)
Query: 1105 SLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLDVEVHVQDALAPVHTQSAWGLEVAL 1164
++N +I + SN+ + IG + VE +D++ H ++V +
Sbjct: 1577 TVNELITIIGHGFSNLPWANKVTIGSYPCV------VEESSEDSIT-CHIDPQNSMDVGI 1629
Query: 1165 -PPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFSIEPCCGSLLGGTILSISGIGFSR 1223
+ ++ + +IN +S D L + + P GS G T ++I G GF+
Sbjct: 1630 RETVTLTVYNLGTAINTLS---NEFDRRFVLLPNIDLVLPNAGSTTGMTSVTIKGSGFAV 1686
Query: 1224 DPALVWVLVGNRSCDIVNLTEASIWCETLPAPQ---IPDAGAPTVPAAVEVWAGNRFFAR 1280
A V VL+G+ C ++++ +I CET PA Q D VPA + GN
Sbjct: 1687 SSAGVKVLMGHFPCKVLSVNYTAIECETSPAAQQLVDVDLLIHGVPAQCQ---GN----- 1738
Query: 1281 GPSPSLVGKGFTFMYEAAATPVVTAMQGEITNSSLSLHVGGSNLSNSVILLGNLNCDVET 1340
TF Y + TP +T + S+ + + G LG + D+
Sbjct: 1739 ----------CTFSYLESITPYITGVFPNSVIGSVKVLIEGEG-------LGTVLEDIAV 1781
Query: 1341 QSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSVVLQQFAV--------MPRIM 1392
F GN + +++ A + PL V G ++SVV+ + P +
Sbjct: 1782 --FIGNQQFRAIEVNENNITALVTPLPV-----GHHSVSVVVGSKGLALGNLTVSSPPVA 1834
Query: 1393 AIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDHTILCQVSLEGDPL 1452
++ P+ GS GGT L + G +V + G C I+S+ + + C+
Sbjct: 1835 SLSPTSGSIGGGTTLVITGNGFYPGNTTVTI---GDEPCQIISINPNEVYCRTP------ 1885
Query: 1453 PGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLTTVLIRGQRLATT 1512
G + ++V + VN + E +P + + + T + I G
Sbjct: 1886 AGTTGMVDVKIFVNTI---AYPPLLFTYALEDTPFLRGIIPSRGPPGTEIEITGSNFGFE 1942
Query: 1513 ADEPMVFVDDQLPCNVTFFNASHVVCQTRDLAPGPHYLSVFYTRNGYACSGNVSRHFYIM 1572
E V +++ + CNVT N S V C D A G + + + G A S V F
Sbjct: 1943 ILEISVMINN-IQCNVTMANDSVVQCIVGDHAGGTFPVMMHHKTKGSAMSTVV---FEYP 1998
Query: 1573 PQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCL-TVNIGAELIRCIVPTGN 1631
+ + P S GG +T+ GTG QN+ + + + + + C +P+ N
Sbjct: 1999 LNIQNINPSQGSFGGGQTMTVTGTGFNPQNSIILVCGSECAIDRLRSDYTTLLCEIPSNN 2058
Query: 1632 GSVA 1635
G+ A
Sbjct: 2059 GTGA 2062
Score = 88.2 bits (217), Expect = 1e-16
Identities = 114/488 (23%), Positives = 201/488 (41%), Gaps = 45/488 (9%)
Query: 900 ANQHTQVVVRVNDVPAHCPGSCSFQYLQGSTPCVHSVW-YSIDGDINLMIYITGTGFSGD 958
A Q V + ++ VPA C G+C+F YL+ TP + V+ S+ G + ++ I G G
Sbjct: 1718 AQQLVDVDLLIHGVPAQCQGNCTFSYLESITPYITGVFPNSVIGSVKVL--IEGEGLGTV 1775
Query: 959 SQFLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILMLVRPSGLAISATGEDLFLNVK 1018
+ + V + + I N+ N+ LPVG H + ++V GLA+ +L ++
Sbjct: 1776 LEDIAVFIGNQQFRAIEVNENNITALVTPLPVGHHSVSVVVGSKGLALG----NLTVS-S 1830
Query: 1019 PRLDMVEPSRAADIGGLWATIRGSSL-EGVSLILFGSYSCAINVATSNSSRIQCKVPPRG 1077
P + + P+ + GG I G+ G + + G C + + N + + C+ P G
Sbjct: 1831 PPVASLSPTSGSIGGGTTLVITGNGFYPGNTTVTIGDEPC--QIISINPNEVYCRT-PAG 1887
Query: 1078 KDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGV-ARLMNY 1136
G +V+V + A P FTY P + R I G I + +
Sbjct: 1888 TTG-MVDVKIFVNTI-AYPPLLFTYALEDTPFL----RGIIPSRGPPGTEIEITGSNFGF 1941
Query: 1137 TDLDVEVHVQDALAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLT 1196
L++ V + + V + ++ + G V ++ + S + +Y
Sbjct: 1942 EILEISVMINNIQCNVTMANDSVVQCIVGDHAGG--TFPVMMHHKTKGSAMSTVVFEYPL 1999
Query: 1197 EVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQ 1256
+ +I P GS GG ++++G GF+ +++ V + D + ++ CE
Sbjct: 2000 NIQNINPSQGSFGGGQTMTVTGTGFNPQNSIILVCGSECAIDRLRSDYTTLLCE------ 2053
Query: 1257 IPDAGAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGE--ITNSS 1314
IP A EV N + S S+ F Y + TP++TA+ + T
Sbjct: 2054 IPSNNGTGAEQACEVSVVN---GKDLSQSMT----PFTYAVSLTPLITAVSPKRGSTAGG 2106
Query: 1315 LSLHVGGSNLSNSV----ILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQ 1370
L V GS S ++ I + CDVE N + C H+L +G P+ V
Sbjct: 2107 TRLTVVGSGFSENMEDVHITIAEAKCDVE----YSNKTHIICMTDAHTL-SGWAPVCVHI 2161
Query: 1371 KQMGFANM 1378
+ +G A +
Sbjct: 2162 RGVGMAKL 2169
Score = 77.0 bits (188), Expect = 3e-13
Identities = 82/356 (23%), Positives = 149/356 (41%), Gaps = 32/356 (8%)
Query: 1449 GDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTN----TSGSLTTVLI 1504
GD L S V V VNG+ ++C G+C +P++ A+S + G++ T++
Sbjct: 1030 GDLLRTPSQQPQVEVYVNGIPAKCSGDCGFTWDSNITPLVLAISPSQGSYEEGTILTIVG 1089
Query: 1505 RGQRLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLAPGPHYLSVFYTRNGYACS-G 1563
G + + + C++ + + CQ + + G ++V G A + G
Sbjct: 1090 SG----FSPSSAVTVSVGPVGCSLLSVDEKELKCQILNGSAGHAPVAVSMADVGLAQNVG 1145
Query: 1564 NVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGAELI 1623
+F Q+ H +P + S+ GG+LLT+ G G + V + +TC + I
Sbjct: 1146 GEEFYFVYQSQISHIWPDSGSIAGGTLLTLSGFGF--NENSKVLVGNETCNVIEGDLNRI 1203
Query: 1624 RCIVP-TGNGSVALEIEVDGLWYHI-GVIGYNKAFTPELISIS-QSDDILTFAVAQISG- 1679
C P G+V + + +G YN TP + S + IL I G
Sbjct: 1204 TCRTPKKTEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPKVRTILGEVNLTIKGY 1263
Query: 1680 ------AANIDIFIGMSPCVGVSGNHTVLQCVVPSLPAGEYHVRGYDCIRGWASSAL--- 1730
N+ +++G C + N T ++C++P L G++ + Y +R W ++
Sbjct: 1264 NFGNELTQNMAVYVGGKTCQILHWNFTDIRCLLPKLSPGKHDI--YVEVRNWGFASTRDK 1321
Query: 1731 VFTSRVIITAVTENF----GCLGGRLVHVFGAGFS--PGNVSAAVCGAPCRVLANA 1780
+ +S + VT F GG + + G GFS P + + PC V +++
Sbjct: 1322 LNSSIQYVLEVTSMFPQRGSLFGGTEITIRGFGFSTIPAENTVLLGSIPCNVTSSS 1377
Score = 59.3 bits (142), Expect = 6e-08
Identities = 38/85 (44%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 1193 QYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETL 1252
Q EV I P GS+ GGT L+ISG F + V VLVG CDI+N+TE SI C+T
Sbjct: 267 QTYAEVTMIFPSQGSIRGGTTLTISGRFFDQTDFPVRVLVGGEPCDILNVTENSICCKTP 326
Query: 1253 PAPQIPDAGAPTVPA-AVEVWAGNR 1276
P P I P +EVW +R
Sbjct: 327 PKPHILKTVYPGGRGLKLEVWNNSR 351
Score = 47.4 bits (111), Expect = 2e-04
Identities = 110/460 (23%), Positives = 166/460 (36%), Gaps = 98/460 (21%)
Query: 939 SIDGDINLMIYITGTGFSGDSQFLQVTVNKTSCKVIFSNQTNVVCQTDLLPVGMHRILML 998
SI G L+I TG GF + VT+ C++I N V C+T GM + +
Sbjct: 1842 SIGGGTTLVI--TGNGFYPGNT--TVTIGDEPCQIISINPNEVYCRTPAGTTGMVDVKIF 1897
Query: 999 VRPSGLAISATGEDLFLNVKPRLDMVEPSRAADIGGLWATIRGSSLEGVSL---ILFGSY 1055
V +A L P L + PSR G I GS+ L ++ +
Sbjct: 1898 VNT--IAYPPLLFTYALEDTPFLRGIIPSRGPP--GTEIEITGSNFGFEILEISVMINNI 1953
Query: 1056 SCAINVATSNSSRIQCKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSR 1115
C NV +N S +QC V G V+ T S+++ V+
Sbjct: 1954 QC--NVTMANDSVVQCIVGDHA------------GGTFPVMMHHKTKGSAMSTVVFEYPL 1999
Query: 1116 NISNI-------AGGETLVI-------------------GVARLMN-YTDLDVEVHVQDA 1148
NI NI GG+T+ + + RL + YT L
Sbjct: 2000 NIQNINPSQGSFGGGQTMTVTGTGFNPQNSIILVCGSECAIDRLRSDYTTL--------- 2050
Query: 1149 LAPVHTQSAWGLEVALPPLPAGLHRISVSINGVSIHSQGVDLH--IQYLTEVFSIEPCCG 1206
L + + + G E A +SV +NG + + + ++ P G
Sbjct: 2051 LCEIPSNNGTGAEQAC--------EVSV-VNGKDLSQSMTPFTYAVSLTPLITAVSPKRG 2101
Query: 1207 SLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLP------AP---QI 1257
S GGT L++ G GFS + V + + CD+ + I C T AP I
Sbjct: 2102 STAGGTRLTVVGSGFSENMEDVHITIAEAKCDVEYSNKTHIICMTDAHTLSGWAPVCVHI 2161
Query: 1258 PDAGAPTVPAA----VEVWAGNRFFARGPSPS------LVGKGFTFMYEAAATPVVTAMQ 1307
G + A V+ W+ N F G SP ++ KG T + + +TP++ +
Sbjct: 2162 RGVGMAKLDNADFLYVDAWSSN-FSWGGKSPPEEGSLVVITKGQTILLD-QSTPILKMLL 2219
Query: 1308 GEITNSSLSLHVGGSNLSNSVILL---GNLNCDVETQSFQ 1344
I +L L IL+ G L ET FQ
Sbjct: 2220 --IQGGTLIFDEADIELQAENILITDGGVLQIGTETSPFQ 2257
Score = 46.6 bits (109), Expect = 4e-04
Identities = 36/131 (27%), Positives = 59/131 (45%), Gaps = 13/131 (9%)
Query: 195 NRQMGSCYPIQEDHGLGTLQCHVEGDYIGSQNVSFSVFNKGKSMV--------HKKAWLI 246
N +GS + E GLGT+ + +IG+Q N+ H ++
Sbjct: 1757 NSVIGSVKVLIEGEGLGTVLEDI-AVFIGNQQFRAIEVNENNITALVTPLPVGHHSVSVV 1815
Query: 247 SAKQDLFLYQ---THSEILSVFPETGSLGGRTNITITGD-FFDNSAQVTIAGIPCDIRHV 302
+ L L + + S+ P +GS+GG T + ITG+ F+ + VTI PC I +
Sbjct: 1816 VGSKGLALGNLTVSSPPVASLSPTSGSIGGGTTLVITGNGFYPGNTTVTIGDEPCQIISI 1875
Query: 303 SPRKIECTTRA 313
+P ++ C T A
Sbjct: 1876 NPNEVYCRTPA 1886
Score = 45.4 bits (106), Expect = 0.001
Identities = 80/332 (24%), Positives = 128/332 (38%), Gaps = 84/332 (25%)
Query: 24 HIEPEEGSLAGGTWITVIFDGLELGVLYPNNGSQLEIHLVNVNMVVPALRSVPCDVFPVF 83
HI P+ GS+AGGT +T+ G N S++ + N++
Sbjct: 1159 HIWPDSGSIAGGTLLTLSGFGF-------NENSKVLVGNETCNVIEG------------- 1198
Query: 84 LDLPVVTCRTRSVLSEAHEGLYFLEAYFGGQLVSSPNPGPRDSCTFKFSKAQTPIVHQVY 143
DL +TCRT + EG + G ++ RD+ F ++ QTPI+
Sbjct: 1199 -DLNRITCRT----PKKTEGTVDISVTTNGFQATA-----RDA--FSYNCLQTPIITDFS 1246
Query: 144 PPSGVPGKLIHVYGWIITGRLETFDFDAEYIDSPVILEAQGDKWVTPCSLINRQMGSCYP 203
P K+ + G + ++ ++F E + + G K C +++
Sbjct: 1247 P------KVRTILGEVNL-TIKGYNFGNELTQNMAVYV--GGK---TCQILHWNFTD--- 1291
Query: 204 IQEDHGLGTLQCHVEGDYIGSQNVSFSVFNKGKSMVHKKAWLISAKQDLFLYQTHSEILS 263
++C + G ++ V N G + K L S+ Q + E+ S
Sbjct: 1292 ---------IRCLLPKLSPGKHDIYVEVRNWGFASTRDK--LNSSIQYVL------EVTS 1334
Query: 264 VFPETGSLGGRTNITITGDFFDN---SAQVTIAGIPCDIRHVSPRKIECTTRAPGKDVRL 320
+FP+ GSL G T ITI G F V + IPC++ S I+C + G R+
Sbjct: 1335 MFPQRGSLFGGTEITIRGFGFSTIPAENTVLLGSIPCNVTSSSENVIKCILHSTGNIFRI 1394
Query: 321 TTPQPGNRGLLFEVGDAVEGLELTEATPGYRW 352
T N G D+V GL GY W
Sbjct: 1395 T-----NNG-----KDSVHGL-------GYAW 1409
Score = 45.1 bits (105), Expect = 0.001
Identities = 69/303 (22%), Positives = 115/303 (37%), Gaps = 57/303 (18%)
Query: 1193 QYLTEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVL----VGNR----------SCD 1238
Q + +V I P GS+ G T L+I G GFS+ + + +GN +CD
Sbjct: 28 QIIPKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAELGNSVQLISSFQSITCD 87
Query: 1239 IVNLTEAS--IWCETLPAPQ-----------IPDAGAPTVPAAVEVWAGNRFFARGPSPS 1285
+ S I C T P+ +P T + W +P+
Sbjct: 88 VEKDASHSTQITCYTRAMPEDSYTVRVSVDGVPVTENNTCKGHINSWECTFNAKSFRTPT 147
Query: 1286 LVGKGFTFMYEAAATP-VVTAMQG----EITNSSLSLHVGGSNLSNSVILLGNLNCDVET 1340
+ + + TP + +QG ++ S+++L G N+ + +G + C++
Sbjct: 148 IRS-----ITPLSGTPGTLITIQGRIFTDVYGSNIALSSNGKNVRILRVYIGGMPCELLI 202
Query: 1341 QSFQGNVSL----------------SGCSIPLHSLEAGI---YPLQVRQKQMGFANMSVV 1381
L +G I H++ + Y QK F +
Sbjct: 203 PQSDNLYGLKLDHPNGDMGSMVCKTTGTFIGHHNVSFILDNDYGRSFPQKMAYFVSSLNK 262
Query: 1382 LQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCVILSLGDHTI 1441
+ F + IFPSQGS GGT LT+ G + VRV L G C IL++ +++I
Sbjct: 263 IAMFQTYAEVTMIFPSQGSIRGGTTLTISGRFFDQTDFPVRV-LVGGEPCDILNVTENSI 321
Query: 1442 LCQ 1444
C+
Sbjct: 322 CCK 324
Score = 41.6 bits (96), Expect = 0.014
Identities = 30/115 (26%), Positives = 58/115 (50%), Gaps = 15/115 (13%)
Query: 213 LQCHVEGDYIGSQNVSFSVFNKGKSMVHKKAWLISAKQDLFLYQTHSEILSVFPETGSLG 272
L+C + G V+ S+ + G A + ++ F+YQ S+I ++P++GS+
Sbjct: 1117 LKCQILNGSAGHAPVAVSMADVGL------AQNVGGEEFYFVYQ--SQISHIWPDSGSIA 1168
Query: 273 GRTNITITGDFFDNSAQVTIAGIPCDIRHVSPRKIECTTRAPGK-----DVRLTT 322
G T +T++G F+ +++V + C++ +I C R P K D+ +TT
Sbjct: 1169 GGTLLTLSGFGFNENSKVLVGNETCNVIEGDLNRITC--RTPKKTEGTVDISVTT 1221
Score = 39.7 bits (91), Expect = 0.051
Identities = 65/299 (21%), Positives = 115/299 (38%), Gaps = 58/299 (19%)
Query: 1387 VMPRIMAIFPSQGSACGGTILTVRGL-LLNSRRRSVRVDLSGPFTCVILSLGDHTILCQV 1445
++P++ I P GS G T LT+RG + + + VD + V L +I C V
Sbjct: 29 IIPKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAELGNSVQLISSFQSITCDV 88
Query: 1446 SLEGD----------PLPGASFSLNVTVLVNGLT--SECQGN-----CTLFIREEASPVM 1488
+ +P S+++ V+V +T + C+G+ CT + +P +
Sbjct: 89 EKDASHSTQITCYTRAMPEDSYTVRVSVDGVPVTENNTCKGHINSWECTFNAKSFRTPTI 148
Query: 1489 DALS--TNTSGSLTTVL------IRGQRLATTADEPMVFV----DDQLPCNVTFFNASH- 1535
+++ + T G+L T+ + G +A +++ V + +PC + + +
Sbjct: 149 RSITPLSGTPGTLITIQGRIFTDVYGSNIALSSNGKNVRILRVYIGGMPCELLIPQSDNL 208
Query: 1536 --------------VVCQTRDLAPGPHYLSVFYTRNGY-----------ACSGNVSRHFY 1570
+VC+T G H +S F N Y S N F
Sbjct: 209 YGLKLDHPNGDMGSMVCKTTGTFIGHHNVS-FILDNDYGRSFPQKMAYFVSSLNKIAMFQ 267
Query: 1571 IMPQVFHYFPKNFSLHGGSLLTIEGTGL-RGQNTTSVYIDQQTCLTVNIGAELIRCIVP 1628
+V FP S+ GG+ LTI G + V + + C +N+ I C P
Sbjct: 268 TYAEVTMIFPSQGSIRGGTTLTISGRFFDQTDFPVRVLVGGEPCDILNVTENSICCKTP 326
Score = 36.2 bits (82), Expect = 0.57
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 261 ILSVFPETGSLGGRTNITITGDFFDNSAQ---VTIAGIPCDIRHVSPRKIECTTRA 313
I +V P+ GS G T +T+ G F + + +TIA CD+ + + I C T A
Sbjct: 2093 ITAVSPKRGSTAGGTRLTVVGSGFSENMEDVHITIAEAKCDVEYSNKTHIICMTDA 2148
Score = 35.0 bits (79), Expect = 1.3
Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 13/121 (10%)
Query: 198 MGSCYPIQEDHGLGTLQCHVEG----DYIGSQNVSFSVFNKGKSMVHKKAWLISAKQDLF 253
+GS + E+ ++ CH++ D + V+ +V+N G ++ L + F
Sbjct: 1600 IGSYPCVVEESSEDSITCHIDPQNSMDVGIRETVTLTVYNLGTAI----NTLSNEFDRRF 1655
Query: 254 LYQTHSEILSVFPETGSLGGRTNITITGDFFDNSA---QVTIAGIPCDIRHVSPRKIECT 310
+ + ++ V P GS G T++TI G F S+ +V + PC + V+ IEC
Sbjct: 1656 VLLPNIDL--VLPNAGSTTGMTSVTIKGSGFAVSSAGVKVLMGHFPCKVLSVNYTAIECE 1713
Query: 311 T 311
T
Sbjct: 1714 T 1714
>gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
Length = 1383
Score = 66.2 bits (160), Expect = 5e-10
Identities = 101/415 (24%), Positives = 160/415 (38%), Gaps = 126/415 (30%)
Query: 2874 DIASGNERIIVEDAVDWRPHDKIVLSSSSYEPHEAEVLTV---KEVKGHHVRIYERLKHR 2930
++ G + +++D W+P D+IV++S+ Y ++AE T+ E V++ E +
Sbjct: 411 EVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFL 470
Query: 2931 HIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQL 2988
H+G + DG + + AEVG+LTRNI IQ +V SC F + F G + +
Sbjct: 471 HMGEI---IDG--VDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMI 522
Query: 2989 LN---------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGI 3028
+ VE+++ G L V++ +++ ++H S I
Sbjct: 523 MKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCI 582
Query: 3029 HAAASHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP-------------- 3071
++G+L+ D I F T GH LE Q T+ +NL L+T+P
Sbjct: 583 TVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCT 641
Query: 3072 -------------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-- 3110
A ST W+A + NL N AGS+ G HK
Sbjct: 642 TMRDKVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEP 695
Query: 3111 ---CSSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNC 3141
S +LL + +N HS+ L+ + G LDN
Sbjct: 696 TGESSGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNS 754
Query: 3142 TR-----------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179
R I +AFKN D GA + + ++N DN IGL
Sbjct: 755 ARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 808
Score = 65.5 bits (158), Expect = 9e-10
Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%)
Query: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985
R +W P + V ++ G +L L ++ ++ +++ GG L+F I LR
Sbjct: 119 RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176
Query: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042
H IL+ DGG L IG+E ++ +A ITLYG S P +G KF+ V GTL LHG+
Sbjct: 177 HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235
Score = 56.2 bits (134), Expect = 5e-07
Identities = 80/338 (23%), Positives = 138/338 (40%), Gaps = 53/338 (15%)
Query: 2064 LEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTDLYLKSPLRYSHNFTENWVAG 2123
L+D W PGD++V+ S EE + + + +K ++ + F
Sbjct: 421 LDDVSSWKPGDQIVVASTD--YSMYQAEEFTLLPCSECSHFQVK--VKETPQFLHMGEII 476
Query: 2124 EHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDM 2183
+ ++A V +L+R+I IQG + + SC N C + + G
Sbjct: 477 DGVDMRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-- 520
Query: 2184 GARVIVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNS 2239
+I+++F S V+LK + Q +G+ H HL + G R + F+ G ++ +S
Sbjct: 521 ---MIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHS 577
Query: 2240 FSRGLSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII-- 2297
FSR +++ GT GL + + ++ LGH + E R + + G ++
Sbjct: 578 FSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPT 633
Query: 2298 -RNNVIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL 2347
RNN + + N + + S +I P N + N G AG Y FH
Sbjct: 634 DRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHK 693
Query: 2348 -MTNQTSQAPLLS---------FTQNIAHSCTRYGLFV 2375
T ++S LL+ F N HS + GLF+
Sbjct: 694 EPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 731
>gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]
Length = 1320
Score = 65.5 bits (158), Expect = 9e-10
Identities = 42/119 (35%), Positives = 63/119 (52%), Gaps = 8/119 (6%)
Query: 1930 RTHSWFPERLPQDGDNVTVENGQLLLLDTNTSILNLLHIKGGKLIFM----APGPIELRA 1985
R +W P + V ++ G +L L ++ ++ +++ GG L+F I LR
Sbjct: 119 RLRNWDPGQ--DSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRT 176
Query: 1986 HAILVSDGGELRIGSEDKPFQGRAQITLYGSSYSTPFFP-YGVKFLAVR-NGTLSLHGS 2042
H IL+ DGG L IG+E ++ +A ITLYG S P +G KF+ V GTL LHG+
Sbjct: 177 HYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGA 235
Score = 49.7 bits (117), Expect = 5e-05
Identities = 68/274 (24%), Positives = 114/274 (41%), Gaps = 49/274 (17%)
Query: 2128 LKATVALLSRSITIQGNLTNEREKLLVSCQEANAPEGNLQHCLYSMSEKMLGSRDMGARV 2187
++A V +L+R+I IQG + + SC N C + + G +
Sbjct: 418 MRAEVGILTRNIVIQGEVED-------SCYAEN-------QCQFFDYDTFGGHI-----M 458
Query: 2188 IVQSFPE-EPSQVQLKGVQFQVLGQ-AFHKHL-SSLTLVGAMRES-FIQGCTVRNSFSRG 2243
I+++F S V+LK + Q +G+ H HL + G R + F+ G ++ +SFSR
Sbjct: 459 IMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRC 518
Query: 2244 LSMCGTLGLKVDSNVFYNILGHALLVGTCTEMRYISWEAIHGRKDDWSGHGNII---RNN 2300
+++ GT GL + + ++ LGH + E R + + G ++ RNN
Sbjct: 519 ITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQR----NTLFHNLGLLTKPGTLLPTDRNN 574
Query: 2301 VIIQVSGAEGLSN------PEMLTPSGIYICSPTNVIEGNRVCG---AGYGYFFHL-MTN 2350
+ + N + + S +I P N + N G AG Y FH T
Sbjct: 575 SMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTG 634
Query: 2351 QTSQAPLLS---------FTQNIAHSCTRYGLFV 2375
++S LL+ F N HS + GLF+
Sbjct: 635 ESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFI 668
Score = 40.8 bits (94), Expect = 0.023
Identities = 84/351 (23%), Positives = 126/351 (35%), Gaps = 118/351 (33%)
Query: 2935 VHVTEDGRHIRLAAEVGLLTRNIQIQPDV--SCRGRLFVGSFRKSSREEFSGVLQLLN-- 2990
+H+ E + + AEVG+LTRNI IQ +V SC F + F G + ++
Sbjct: 407 LHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFF---DYDTFGGHIMIMKNF 463
Query: 2991 -------VEIQNFGSP----------LYSSVEF-SNVSAGSWIISSTLHQSCGGGIHAAA 3032
VE+++ G L V++ +++ ++H S I
Sbjct: 464 TSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHG 523
Query: 3033 SHGVLLNDNIVFGTAGHGIDLEG---QAYTVTNNLVVLMTQP------------------ 3071
++G+L+ D I F T GH LE Q T+ +NL L+T+P
Sbjct: 524 TNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNL-GLLTKPGTLLPTDRNNSMCTTMRD 582
Query: 3072 ---------------AWSTIWVAGIKVNQVKDINLHGNVVAGSERLGFHIRGHK-----C 3111
A ST W+A + NL N AGS+ G HK
Sbjct: 583 KVFGNYIPVPATDCMAVSTFWIAH------PNNNLINNAAAGSQDAGIWYLFHKEPTGES 636
Query: 3112 SSCELL----------WSDNVAHSSLHGLHLYKESG----------------LDNCTR-- 3143
S +LL + +N HS+ L+ + G LDN R
Sbjct: 637 SGLQLLAKPELTPLGIFYNNRVHSNFKA-GLFIDKGVKTTNSSAADPREYLCLDNSARFR 695
Query: 3144 ---------------ISGFLAFKNFDYGAMLHVENSVEIENITLVDNTIGL 3179
I +AFKN D GA + + ++N DN IGL
Sbjct: 696 PHQDANPEKPRVAALIDRLIAFKNNDNGAWVR-GGDIIVQNSAFADNGIGL 745
>gi|38638698 KIAA1199 [Homo sapiens]
Length = 1361
Score = 61.2 bits (147), Expect = 2e-08
Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 5/116 (4%)
Query: 1945 NVTVENGQLLLLDTNTSILNLLHIKGGKLIFMAPG-PIELRAHAILVSDGGELRIGSEDK 2003
+V + G+ LLL ++ ++ ++ +GGKL+ PI LR IL+ +GGEL GS
Sbjct: 55 HVHIGQGKTLLLTSSATVYSIHISEGGKLVIKDHDEPIVLRTRHILIDNGGELHAGSALC 114
Query: 2004 PFQGRAQITLYGSSYS--TPFFPYGVKFLAV-RNGTLSLHGSLPEVIVTCLRATAH 2056
PFQG I LYG + P YG+K++ V + G L LHG ++ T L T H
Sbjct: 115 PFQGNFTIILYGRADEGIQPDPYYGLKYIGVGKGGALELHGQ-KKLSWTFLNKTLH 169
Score = 44.3 bits (103), Expect = 0.002
Identities = 57/278 (20%), Positives = 115/278 (41%), Gaps = 59/278 (21%)
Query: 2824 QKLLILLRASEGVFCDR--------MNGIHIDPGTIGVYGKVHLYSAY------------ 2863
+K+ L +A G C+R M+G+++ + G+ + ++ Y
Sbjct: 341 EKISDLWKAHPGKICNRPIDIQATTMDGVNLSTEVVYKKGQDYRFACYDRGRACRSYRVR 400
Query: 2864 -----PKNSWTHLGADIASGNERIIVEDAVD-WRPHDKIVLSSSSYEPHEAE---VLTVK 2914
P + D + + +ED V W+P D +V++S+ Y ++AE VL +
Sbjct: 401 FLCGKPVRPKLTVTIDTNVNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCR 460
Query: 2915 EVKGHHVRIYERLKHRHIGSVHVTEDGRHIRLAAEVGLLTRNIQIQPDVSCR---GRLFV 2971
+ V++ + + HIG E+ + + AEVGLL+RNI + ++ + R +
Sbjct: 461 SCAPNQVKVAGKPMYLHIG-----EEIDGVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHI 515
Query: 2972 GSFRKSSREEFSGVLQ---------LLNVEIQNFGSPLYSSVEFSNVSAG---------- 3012
+F + F G ++ L E+++ G L AG
Sbjct: 516 CNF--FDFDTFGGHIKFALGFKAAHLEGTELKHMGQQLVGQYPIHFHLAGDVDERGGYDP 573
Query: 3013 -SWIISSTLHQSCGGGIHAAASHGVLLNDNIVFGTAGH 3049
++I ++H + + S+G+L+ D + + + GH
Sbjct: 574 PTYIRDLSIHHTFSRCVTVHGSNGLLIKDVVGYNSLGH 611
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 51.6 bits (122), Expect = 1e-05
Identities = 67/278 (24%), Positives = 106/278 (38%), Gaps = 15/278 (5%)
Query: 1389 PRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDL-SGPFTCVILSLGDHTILCQVSL 1447
P I AI P G GGT+LT+RG L R V + G C L +T+ ++
Sbjct: 891 PEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLP-DRYTVSEEIVC 949
Query: 1448 EGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLTTVLIRGQ 1507
P PG L+ V VN + ++ + + G T + I G
Sbjct: 950 VTGPAPG---PLSGVVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGG--TRITIHGN 1004
Query: 1508 RLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLA-PGPHYLSVFYTRNGYACSGNVS 1566
L E V V+D PC + + C + A P P + V + R G GN++
Sbjct: 1005 DL-HVGSELQVLVNDTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRG-CVHGNLT 1062
Query: 1567 RHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSV---YIDQQTCLTVNIGAELI 1623
+ P + P+ + GG +T+ G S+ +I ++ L + + LI
Sbjct: 1063 FWYMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKVLNSTLI 1122
Query: 1624 RCIVP--TGNGSVALEIEVDGLWYHIGVIGYNKAFTPE 1659
C P N S ++ ++G Y V + PE
Sbjct: 1123 TCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPE 1160
Score = 48.9 bits (115), Expect = 8e-05
Identities = 77/281 (27%), Positives = 121/281 (43%), Gaps = 39/281 (13%)
Query: 1197 EVFSIEPCCGSLLGGTILSISGIGFSRDPALV--WVLVGNRSCDIV---NLTEASIWCET 1251
E+ +IEP G L GGT+L+I G R + V V +G +C+ + I C T
Sbjct: 892 EIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVT 951
Query: 1252 LPAPQIPDAGAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEIT 1311
PAP P +G TV A+ E + +RF P ++ T A IT
Sbjct: 952 GPAPG-PLSGVVTVNASKEGKSRDRFSYVLP----------LVHSLEPTMGPKAGGTRIT 1000
Query: 1312 NSSLSLHVGGSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQK 1371
LHVG S +L+ + D T+ + + S++ C++P +L A + P+ VR +
Sbjct: 1001 IHGNDLHVG----SELQVLVN--DTDPCTELMRTDTSIA-CTMPEGALPAPV-PVCVRFE 1052
Query: 1372 QMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTC 1431
+ G + ++ + P I AI P + GG +TV G R + +
Sbjct: 1053 RRGCVHGNLTF-WYMQNPVITAISPRRSPVSGGRTITVAG---------ERFHMVQNVSM 1102
Query: 1432 VILSLGDHTILCQV---SLEGDPLPGA--SFSLNVTVLVNG 1467
+ +G LC+V +L P PGA + S V +NG
Sbjct: 1103 AVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFFING 1143
Score = 37.4 bits (85), Expect = 0.26
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 7/136 (5%)
Query: 1012 DLFLNVKPRLDMVEPSRAADIGGLWATIRGSSLE---GVSLILFGSYSCAINVATSNSSR 1068
D F V P + +EP+ GG TI G+ L + +++ + C + T S
Sbjct: 974 DRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTS-- 1031
Query: 1069 IQCKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVI 1128
I C +P + +R + + T+ NPVI +S S ++GG T+ +
Sbjct: 1032 IACTMPEGALPAPVP--VCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITV 1089
Query: 1129 GVARLMNYTDLDVEVH 1144
R ++ + VH
Sbjct: 1090 AGERFHMVQNVSMAVH 1105
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 43.9 bits (102), Expect = 0.003
Identities = 77/346 (22%), Positives = 145/346 (41%), Gaps = 55/346 (15%)
Query: 1323 NLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSVVL 1382
+L + +LLGN +C +L+ +++L+ + P + NMS+++
Sbjct: 597 DLKKTRVLLGNESC-----------TLTLSESTMNTLKCTVGPAMNKH-----FNMSIII 640
Query: 1383 Q------QFA----VMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCV 1432
Q++ V P I +I P G GGT+LT+ G LNS S + + G TC
Sbjct: 641 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNS-GNSRHISIGGK-TCT 698
Query: 1433 ILSLGDHTILCQVSLEGDPLPGASFSLNVTV-LVNGLTSECQGNCTLFIREEASPVMDAL 1491
+ S+ + + C + F++ + + L N TS +F E V +
Sbjct: 699 LKSVSNSILECYTPAQ---TISTEFAVKLKIDLANRETS-------IFSYREDPIVYEIH 748
Query: 1492 STNT--SGSLTTVLIRGQRLATTADEPMVFVDDQLPCNVTFF----NASHVVCQTRDLAP 1545
T + SG +T+ G+ L + + MV + N T + S ++C T
Sbjct: 749 PTKSFISGG-STITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQ 807
Query: 1546 GPHYLSVFYTRNGYACSGNVSRHF---YIMPQVFHYF--PKNFSLHGGSLLTIEGTGLRG 1600
+ T+ + G +S++F Y+ VF F P S+ ++L I+G +
Sbjct: 808 QLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDP 867
Query: 1601 QNTTS--VYIDQQTCLTVNIGAELIRCIVPTGNGSVALEIEVDGLW 1644
+ + + ++C +++ +E + C VP N + L E++ W
Sbjct: 868 EAVKGEVLKVGNKSCENIHLHSEAVLCTVP--NDLLKLNSELNIEW 911
Score = 33.9 bits (76), Expect = 2.8
Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 1050 ILFGSYSCAINVATSNSSRIQCKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPV 1109
+L G+ SC + ++ S + ++C V P +++ + G + F+YV +PV
Sbjct: 603 VLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNG-HGTTQYSTFSYV---DPV 658
Query: 1110 IVTLSRNISNIAGGETLVI 1128
I ++S +AGG L +
Sbjct: 659 ITSISPKYGPMAGGTLLTL 677
Score = 33.5 bits (75), Expect = 3.7
Identities = 69/349 (19%), Positives = 140/349 (40%), Gaps = 40/349 (11%)
Query: 931 PCVHSVWYS---IDGDINLMIYITGTGFSGDSQF----LQVTVNKTSCKVIFSNQTNVVC 983
P ++ V+ + ++G L I GF +++F +V + SC + S T
Sbjct: 563 PAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTL 622
Query: 984 QTDLLP-VGMHRILMLVRPSGLAISATGEDLFLNVKPRLDMVEPSRAADIGGLWATIRGS 1042
+ + P + H + ++ +G T F V P + + P GG T+ G+
Sbjct: 623 KCTVGPAMNKHFNMSIIISNGHG--TTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGN 680
Query: 1043 SLEGVSL--ILFGSYSCAINVATSNSSRIQCKVPPRGKDGRIVNVTVIRGDYSAVLPRAF 1100
L + I G +C + + ++S ++C P + ++ D + F
Sbjct: 681 YLNSGNSRHISIGGKTCTLK--SVSNSILECYTPAQTISTEFA--VKLKIDLANRETSIF 736
Query: 1101 TYVSSLNPVIVTLSRNISNIAGGETLVIGVARLMNYTDLD---VEVHVQDALAPVHTQSA 1157
+Y +P++ + S I+GG T+ GV + +N + + VH V Q
Sbjct: 737 SYRE--DPIVYEIHPTKSFISGGSTIT-GVGKNLNSVSVPRMVINVHEAGRNFTVACQHR 793
Query: 1158 WGLEVALPPLPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFSI------------EPCC 1205
E+ P+ L ++++ + + ++ + L++ F + +P
Sbjct: 794 SNSEIICCTTPS-LQQLNLQL---PLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVM 849
Query: 1206 GSLLGGTILSISGIGFSRDPALVWVL-VGNRSCDIVNLTEASIWCETLP 1253
S+ +L I G + VL VGN+SC+ ++L ++ C T+P
Sbjct: 850 ISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLC-TVP 897
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 40.8 bits (94), Expect = 0.023
Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 3/100 (3%)
Query: 1544 APGPHYLSVFYTRNGYACSGNVSRHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNT 1603
A H+ NG+ + S Y+ P + PK + GG+LLT+ G L N+
Sbjct: 629 AMNKHFNMSIIISNGHGTT-QYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNS 687
Query: 1604 TSVYIDQQTCLTVNIGAELIRCIVP--TGNGSVALEIEVD 1641
+ I +TC ++ ++ C P T + A+++++D
Sbjct: 688 RHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKID 727
Score = 39.3 bits (90), Expect = 0.067
Identities = 76/357 (21%), Positives = 144/357 (40%), Gaps = 59/357 (16%)
Query: 1323 NLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQMGFANMSVVL 1382
+L + +LLGN +C +L+ +++L+ + P + NMS+++
Sbjct: 597 DLKKTRVLLGNESC-----------TLTLSESTMNTLKCTVGPAMNKH-----FNMSIII 640
Query: 1383 Q------QFA----VMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTCV 1432
Q++ V P I +I P G GGT+LT+ G LNS S + + G TC
Sbjct: 641 SNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNS-GNSRHISIGGK-TCT 698
Query: 1433 ILSLGDHTILCQVSLEGDPLPGASFSLNVTV-LVNGLTSECQGNCTLFIRE--------- 1482
+ S+ + + C + F++ + + L N TS + E
Sbjct: 699 LKSVSNSILECYTPAQ---TISTEFAVKLKIDLANRETSIFSYREDPIVYEIHPTKSFIS 755
Query: 1483 ----EASPVMDALSTNTSGSLTTVLIRGQRLATTADEPMVFVDDQLPCNVTFF----NAS 1534
E ++ L SG +T+ G+ L + + MV + N T + S
Sbjct: 756 TWWKEPLNIVSFLFCFASGG-STITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNS 814
Query: 1535 HVVCQTRDLAPGPHYLSVFYTRNGYACSGNVSRHF---YIMPQVFHYF--PKNFSLHGGS 1589
++C T + T+ + G +S++F Y+ VF F P S+ +
Sbjct: 815 EIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNEN 874
Query: 1590 LLTIEGTGLRGQNTTS--VYIDQQTCLTVNIGAELIRCIVPTGNGSVALEIEVDGLW 1644
+L I+G + + + + ++C +++ +E + C VP N + L E++ W
Sbjct: 875 VLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVP--NDLLKLNSELNIEW 929
Score = 33.9 bits (76), Expect = 2.8
Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 1050 ILFGSYSCAINVATSNSSRIQCKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPV 1109
+L G+ SC + ++ S + ++C V P +++ + G + F+YV +PV
Sbjct: 603 VLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSIIISNG-HGTTQYSTFSYV---DPV 658
Query: 1110 IVTLSRNISNIAGGETLVI 1128
I ++S +AGG L +
Sbjct: 659 ITSISPKYGPMAGGTLLTL 677
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 40.4 bits (93), Expect = 0.030
Identities = 49/193 (25%), Positives = 69/193 (35%), Gaps = 8/193 (4%)
Query: 942 GDINLMIYITGTGFSGDSQFLQVTVNKTSCKVIFSNQTN---VVCQT-DLLPVGMHRILM 997
G L I G + L V V K C + S + +VC+ D V H L+
Sbjct: 855 GGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCEIGDASSVRAHDALV 914
Query: 998 --LVRPSGLAISATGEDLFLNVKPRLDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSY 1055
VR A F V P V PSR GG W I GS L S +
Sbjct: 915 EVCVRDCSPHYRALSPKRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVG 974
Query: 1056 SCAINVATSNSSRIQCKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSR 1115
+ + NS I+C PP G +I + + + Y + +P I+ +
Sbjct: 975 GRPCSFSWRNSREIRCLTPPGQSPGSA--PIIININRAQLTNPEVKYNYTEDPTILRIDP 1032
Query: 1116 NISNIAGGETLVI 1128
S +GG L +
Sbjct: 1033 EWSINSGGTLLTV 1045
Score = 38.1 bits (87), Expect = 0.15
Identities = 32/156 (20%), Positives = 58/156 (37%), Gaps = 28/156 (17%)
Query: 1525 PCNVTFFNASHVVCQTRDLAP---------------GPHYLSVFYTRNGYACSGNVSRHF 1569
P + +A +VC+ D + PHY ++ + R
Sbjct: 886 PVESEYISAEQIVCEIGDASSVRAHDALVEVCVRDCSPHYRAL-----------SPKRFT 934
Query: 1570 YIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGAELIRCIVPT 1629
++ P + P L GG+ + IEG+ L + +V + + C + IRC+ P
Sbjct: 935 FVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGRPCSFSWRNSREIRCLTPP 994
Query: 1630 GN--GSVALEIEVDGLWYHIGVIGYNKAFTPELISI 1663
G GS + I ++ + YN P ++ I
Sbjct: 995 GQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRI 1030
Score = 33.1 bits (74), Expect = 4.8
Identities = 51/223 (22%), Positives = 93/223 (41%), Gaps = 19/223 (8%)
Query: 1019 PRLDMVEPSRAADIGGLWATIRGSSL----EGVSL-ILFGSYSCA-INVATSNSSRIQCK 1072
P++ + P GG TI G +L E V L + G C+ + ++ +I C+
Sbjct: 841 PKILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCE 900
Query: 1073 VPP----RGKDGRI-VNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLV 1127
+ R D + V V Y A+ P+ FT+V+ P +S + ++GG +
Sbjct: 901 IGDASSVRAHDALVEVCVRDCSPHYRALSPKRFTFVT---PTFYRVSPSRGPLSGGTWIG 957
Query: 1128 IGVARLMNYTDLDVEVHVQDALAPVHTQSAWGLEVALPPLPA-GLHRISVSINGVSIHSQ 1186
I + L DV V V +++ + PP + G I ++IN + +
Sbjct: 958 IEGSHLN--AGSDVAVSVGGRPCSFSWRNSREIRCLTPPGQSPGSAPIIININRAQLTNP 1015
Query: 1187 GVDLHIQYLTEVFSIEPCCGSLLGGTILSISGIGFS--RDPAL 1227
V + + I+P GGT+L+++G + R+P +
Sbjct: 1016 EVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPRI 1058
Score = 32.7 bits (73), Expect = 6.3
Identities = 69/275 (25%), Positives = 113/275 (41%), Gaps = 45/275 (16%)
Query: 1197 EVFSIEPCCGSLLGGTILSISG--IGFSRDPALVWVLVGNRSCDIVN---LTEASIWCET 1251
++ + P G GGT L+I+G +G + + V VG C V ++ I CE
Sbjct: 842 KILKLSPETGPRQGGTRLTITGENLGLRFEDVRLGVRVGKVLCSPVESEYISAEQIVCE- 900
Query: 1252 LPAPQIPDAGAPTV-PAAVEVWAGNRFFARGPSP---SLVGKGFTFMYEAAATPV---VT 1304
I DA + A VEV R SP +L K FTF+ TP V+
Sbjct: 901 -----IGDASSVRAHDALVEVCV------RDCSPHYRALSPKRFTFV-----TPTFYRVS 944
Query: 1305 AMQGEITNSSLSLHVGGSNL---SNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEA 1361
+G ++ + + + GS+L S+ + +G C S++ + + + P S
Sbjct: 945 PSRGPLSGGTW-IGIEGSHLNAGSDVAVSVGGRPCSF---SWRNSREIRCLTPPGQS--P 998
Query: 1362 GIYPLQVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGL-LLNSRRRS 1420
G P+ + + N V + P I+ I P GGT+LTV G L R
Sbjct: 999 GSAPIIININRAQLTNPEVKYN-YTEDPTILRIDPEWSINSGGTLLTVTGTNLATVREPR 1057
Query: 1421 VRVDLSG---PFTCVILSLGDHTILCQVSLEGDPL 1452
+R G C++ + D T++C+ +P+
Sbjct: 1058 IRAKYGGIERENGCLVYN--DTTMVCRAPSVANPV 1090
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 39.3 bits (90), Expect = 0.067
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 11/112 (9%)
Query: 1319 VGGSNLSNSV------ILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQ 1372
+ GSNL V + + + C V+ Q ++ + SL + AG ++V +
Sbjct: 1090 IRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRG 1149
Query: 1373 MGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRG-LLLNSRRRSVRV 1423
G + Q P++ +IFP++G GGT LT+ G LL R +RV
Sbjct: 1150 RGVSEHDFAYQD----PKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRV 1197
Score = 35.8 bits (81), Expect = 0.74
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 261 ILSVFPETGSLGGRTNITITGDFFDNSAQ-----VTIAGIPCDI---RHVSPRKIECTTR 312
I SV P TG + G T +TI G Q VT+AG+PC + + + C T
Sbjct: 1072 IHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG 1131
Query: 313 APGKDV 318
A G++V
Sbjct: 1132 ASGEEV 1137
Score = 32.7 bits (73), Expect = 6.3
Identities = 39/162 (24%), Positives = 61/162 (37%), Gaps = 12/162 (7%)
Query: 1019 PRLDMVEPSRAADIGGLWATIRGSSL-----EGVSLILFGSYSCAINVATSN-SSRIQCK 1072
P + VEP GG TIRGS+L + + ++ CA++ SS + C
Sbjct: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129
Query: 1073 VPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVAR 1132
G++ + G V F Y +P + ++ AGG L + ++
Sbjct: 1130 TGASGEEVAGATAVEVPGRGRGVSEHDFAY---QDPKVHSIFPARGPRAGGTRLTLNGSK 1186
Query: 1133 LMNYTDLDVEVHVQDA---LAPVHTQSAWGLEVALPPLPAGL 1171
L+ D+ V V D L P E + P PA L
Sbjct: 1187 LLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATL 1228
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 39.3 bits (90), Expect = 0.067
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 11/112 (9%)
Query: 1319 VGGSNLSNSV------ILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQKQ 1372
+ GSNL V + + + C V+ Q ++ + SL + AG ++V +
Sbjct: 1090 IRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRG 1149
Query: 1373 MGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRG-LLLNSRRRSVRV 1423
G + Q P++ +IFP++G GGT LT+ G LL R +RV
Sbjct: 1150 RGVSEHDFAYQD----PKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRV 1197
Score = 35.8 bits (81), Expect = 0.74
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 261 ILSVFPETGSLGGRTNITITGDFFDNSAQ-----VTIAGIPCDI---RHVSPRKIECTTR 312
I SV P TG + G T +TI G Q VT+AG+PC + + + C T
Sbjct: 1072 IHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITG 1131
Query: 313 APGKDV 318
A G++V
Sbjct: 1132 ASGEEV 1137
Score = 32.7 bits (73), Expect = 6.3
Identities = 39/162 (24%), Positives = 61/162 (37%), Gaps = 12/162 (7%)
Query: 1019 PRLDMVEPSRAADIGGLWATIRGSSL-----EGVSLILFGSYSCAINVATSN-SSRIQCK 1072
P + VEP GG TIRGS+L + + ++ CA++ SS + C
Sbjct: 1070 PLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCI 1129
Query: 1073 VPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGVAR 1132
G++ + G V F Y +P + ++ AGG L + ++
Sbjct: 1130 TGASGEEVAGATAVEVPGRGRGVSEHDFAY---QDPKVHSIFPARGPRAGGTRLTLNGSK 1186
Query: 1133 LMNYTDLDVEVHVQDA---LAPVHTQSAWGLEVALPPLPAGL 1171
L+ D+ V V D L P E + P PA L
Sbjct: 1187 LLTGRLEDIRVVVGDQPCHLLPEQQSEQLRCETSPRPTPATL 1228
>gi|23308722 TTK protein kinase [Homo sapiens]
Length = 857
Score = 37.7 bits (86), Expect = 0.20
Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Query: 2581 TPEVSYDLTMTDSRNKTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSL-QYS 2639
T E+S + D+ + + TVN + +NP W++LLL E S+ + +N+ + +YS
Sbjct: 33 TDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGRYS 92
Query: 2640 ATFDNFAPGNY 2650
+ P Y
Sbjct: 93 QAIEALPPDKY 103
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 37.4 bits (85), Expect = 0.26
Identities = 33/100 (33%), Positives = 44/100 (44%), Gaps = 23/100 (23%)
Query: 23 LHIEPEEGSLAGGTWITVIFDGLELGVLYPNNGSQLEIHLVNVNMVVPALRSVPCDVFPV 82
L +EP++G AGGT +T+ G L + GSQ ++ + L VPC V
Sbjct: 898 LSVEPQQGPQAGGTTLTI--HGTHL-----DTGSQEDVRV--------TLNGVPCKVTKF 942
Query: 83 FLDLPVVTCRTRSVLSEAHEGLYFLEAYFGGQLVSSPNPG 122
L VT +A G LE +GG V PNPG
Sbjct: 943 GAQLQCVTG------PQATRGQMLLEVSYGGSPV--PNPG 974
Score = 36.2 bits (82), Expect = 0.57
Identities = 46/176 (26%), Positives = 70/176 (39%), Gaps = 30/176 (17%)
Query: 1301 PVVTAMQGEI--TNSSLSLHVGGSNLSNSV-----ILLGNLNCDVETQSFQGNVSLSGCS 1353
PV+T +Q E + + + GSNL I + NC + + + + + C
Sbjct: 803 PVITRIQPETGPLGGGIRITILGSNLGVQAGDIQRISVAGRNCSFQPERYSVSTRIV-CV 861
Query: 1354 IPLHSLEAGIYPLQ--VRQKQMGFANMSVVLQQFAVM-PRIMAIFPSQGSACGGTILTVR 1410
I EA P V G S QF P+ +++ P QG GGT LT+
Sbjct: 862 I-----EAAETPFTGGVEVDVFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIH 916
Query: 1411 GLLLNS-RRRSVRVDLSGPFTCVILSLGDH------------TILCQVSLEGDPLP 1453
G L++ + VRV L+G C + G +L +VS G P+P
Sbjct: 917 GTHLDTGSQEDVRVTLNG-VPCKVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVP 971
Score = 34.7 bits (78), Expect = 1.7
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 262 LSVFPETGSLGGRTNITITGDFFDNSAQ----VTIAGIPCDIRHVSPRKIECTT 311
LSV P+ G G T +TI G D +Q VT+ G+PC + +++C T
Sbjct: 898 LSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVPCKVTKFG-AQLQCVT 950
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 36.2 bits (82), Expect = 0.57
Identities = 22/78 (28%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 1567 RHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGAELIRCI 1626
++ ++ P V P GG+++TI G L ++ +VY+ QTC I C+
Sbjct: 948 QYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYLGNQTCEFYGRSMSEIVCV 1007
Query: 1627 VP---TGNGSVALEIEVD 1641
P G G V + + VD
Sbjct: 1008 SPPSSNGLGPVPVSVSVD 1025
Score = 32.3 bits (72), Expect = 8.2
Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 8/84 (9%)
Query: 1191 HIQYL---TEVFSIEPCCGSLLGGTILSISGIGFSRDPALVWVLVGNRSCDIVNLTEASI 1247
H QY V S+ P G GGT+++I+G + + V V +GN++C+ + + I
Sbjct: 946 HQQYTFVNPSVLSLNPIRGPESGGTMVTITG-HYLGAGSSVAVYLGNQTCEFYGRSMSEI 1004
Query: 1248 WCETLPAPQIPDAGAPTVPAAVEV 1271
C + P+ G VP +V V
Sbjct: 1005 VCVSPPSSN----GLGPVPVSVSV 1024
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 35.4 bits (80), Expect = 0.97
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 21/122 (17%)
Query: 1019 PRLDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVAT----------SNSSR 1068
P +D VEP GGL TI GS+L F A++VA+ S+R
Sbjct: 858 PSIDAVEPLTGPPEGGLALTILGSNLGRA----FADVQYAVSVASRPCNPEPSLYRTSAR 913
Query: 1069 IQC--KVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETL 1126
I C P G G + I+ + + FTY +PV+++LS AGG L
Sbjct: 914 IVCVTSPAPNGTTGPV--RVAIKSQPPGISSQHFTY---QDPVLLSLSPRWGPQAGGTQL 968
Query: 1127 VI 1128
I
Sbjct: 969 TI 970
Score = 33.1 bits (74), Expect = 4.8
Identities = 39/182 (21%), Positives = 72/182 (39%), Gaps = 37/182 (20%)
Query: 1237 CDIVNLTEASIWC-ETLPAPQIPDAGAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMY 1295
C N + +WC + PA + G P AVE+ P+PS+
Sbjct: 821 CQAANRSLGCLWCADGQPACRY---GPLCPPGAVELLC--------PAPSI--------- 860
Query: 1296 EAAATPVVTAMQGEITNSSLSLHVGGSNLSNS------VILLGNLNCDVETQSFQGNVSL 1349
A P+ +G L+L + GSNL + + + + C+ E ++ + +
Sbjct: 861 -DAVEPLTGPPEG-----GLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARI 914
Query: 1350 SGCSIPLHSLEAGIYPLQVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTV 1409
+ P + G + ++ + G ++ Q P ++++ P G GGT LT+
Sbjct: 915 VCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQD----PVLLSLSPRWGPQAGGTQLTI 970
Query: 1410 RG 1411
RG
Sbjct: 971 RG 972
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 35.4 bits (80), Expect = 0.97
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 21/122 (17%)
Query: 1019 PRLDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVAT----------SNSSR 1068
P +D VEP GGL TI GS+L F A++VA+ S+R
Sbjct: 835 PSIDAVEPLTGPPEGGLALTILGSNLGRA----FADVQYAVSVASRPCNPEPSLYRTSAR 890
Query: 1069 IQC--KVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETL 1126
I C P G G + I+ + + FTY +PV+++LS AGG L
Sbjct: 891 IVCVTSPAPNGTTGPV--RVAIKSQPPGISSQHFTY---QDPVLLSLSPRWGPQAGGTQL 945
Query: 1127 VI 1128
I
Sbjct: 946 TI 947
Score = 33.1 bits (74), Expect = 4.8
Identities = 39/182 (21%), Positives = 72/182 (39%), Gaps = 37/182 (20%)
Query: 1237 CDIVNLTEASIWC-ETLPAPQIPDAGAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMY 1295
C N + +WC + PA + G P AVE+ P+PS+
Sbjct: 798 CQAANRSLGCLWCADGQPACRY---GPLCPPGAVELLC--------PAPSI--------- 837
Query: 1296 EAAATPVVTAMQGEITNSSLSLHVGGSNLSNS------VILLGNLNCDVETQSFQGNVSL 1349
A P+ +G L+L + GSNL + + + + C+ E ++ + +
Sbjct: 838 -DAVEPLTGPPEG-----GLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARI 891
Query: 1350 SGCSIPLHSLEAGIYPLQVRQKQMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTV 1409
+ P + G + ++ + G ++ Q P ++++ P G GGT LT+
Sbjct: 892 VCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQD----PVLLSLSPRWGPQAGGTQLTI 947
Query: 1410 RG 1411
RG
Sbjct: 948 RG 949
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 35.4 bits (80), Expect = 0.97
Identities = 29/124 (23%), Positives = 45/124 (36%), Gaps = 1/124 (0%)
Query: 1011 EDLFLNVKPRLDMVEPSRAADIGGLWATIRGSSLEGVSLILFGSYSCAINVATSNSSRIQ 1070
E ++ V P D V PSR GG TI GSSL+ S + ++ I
Sbjct: 927 EQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQFVRRDAKAIV 986
Query: 1071 CKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVIGV 1130
C + P G + D + + Y + +P + L S I G + +
Sbjct: 987 C-ISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSG 1045
Query: 1131 ARLM 1134
L+
Sbjct: 1046 THLL 1049
Score = 33.9 bits (76), Expect = 2.8
Identities = 37/142 (26%), Positives = 54/142 (38%), Gaps = 20/142 (14%)
Query: 1500 TTVLIRGQRLATTADEPMVFVDDQLPCN---VTFFNASHVVCQTRD-LAPGPHYLSVFYT 1555
T V I G L + E + V + CN + +A +VC+ + L P P V
Sbjct: 856 TRVTIVGDNLGLLSREVGLRVAG-VRCNSIPAEYISAERIVCEMEESLVPSPPPGPV--- 911
Query: 1556 RNGYACSGNVSRHF---------YIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSV 1606
C G+ S F ++ P P GG+ LTI G+ L + +V
Sbjct: 912 ---ELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTV 968
Query: 1607 YIDQQTCLTVNIGAELIRCIVP 1628
+ C V A+ I CI P
Sbjct: 969 TVRDSECQFVRRDAKAIVCISP 990
>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
sapiens]
Length = 1400
Score = 33.1 bits (74), Expect = 4.8
Identities = 35/129 (27%), Positives = 57/129 (44%), Gaps = 23/129 (17%)
Query: 1149 LAPVHTQSAWGLEVALPP--LPAGLHRISVSINGVSIHSQGVDLHIQYLTEVFSIEPCCG 1206
L P+ TQ+ V+L +P G H ++G S+ +G L +++P G
Sbjct: 642 LEPLGTQAVGPTNVSLTVTNMPPGKH---FRVDGTSV-LRGFSFMEPVL---IAVQPLFG 694
Query: 1207 SLLGGTILSISG----IGFSRDPALVWVLVGNRSCDIVNLTEASIWCETLPAPQIPDAGA 1262
GGT L++ G +G SR VLV C + ++E + C T P A
Sbjct: 695 PRAGGTCLTLEGQSLSVGTSRA-----VLVNGTECLLARVSEGQLLCATPPG-----ATV 744
Query: 1263 PTVPAAVEV 1271
+VP +++V
Sbjct: 745 ASVPLSLQV 753
Score = 33.1 bits (74), Expect = 4.8
Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 1587 GGSLLTIEGTGLRGQNTTSVYIDQQTCLTVNIGAELIRCIVPTGN--GSVALEIEVDG 1642
GG+ LT+EG L + +V ++ CL + + C P G SV L ++V G
Sbjct: 698 GGTCLTLEGQSLSVGTSRAVLVNGTECLLARVSEGQLLCATPPGATVASVPLSLQVGG 755
>gi|217416372 coiled-coil domain containing 142 [Homo sapiens]
Length = 743
Score = 33.1 bits (74), Expect = 4.8
Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 2605 DTLSNPRGWMALLLDQETYSLQSENLW-INRSLQYSATFDNFAPGNYLLLVHTDLPP 2660
D L PR +LQ+ LW + R+ QY A +D P ++LLL+ DLPP
Sbjct: 404 DALREPRLRRIFCQPAGLCTLQTTLLWFLGRAQQYLAAWD---PASFLLLIQKDLPP 457
>gi|223029410 talin 1 [Homo sapiens]
Length = 2541
Score = 32.7 bits (73), Expect = 6.3
Identities = 47/206 (22%), Positives = 77/206 (37%), Gaps = 19/206 (9%)
Query: 1989 LVSDGGELRIGSEDKPFQGRAQITLYGS--SYSTPFFPYGVKFLAVRNGTLSLHGS---L 2043
L SD G R+ SE KP A+ GS + +G L + G L S
Sbjct: 1889 LTSDYG--RLASEAKPAAVAAENEEIGSHIKHRVQELGHGCAALVTKAGALQCSPSDAYT 1946
Query: 2044 PEVIVTCLRATAHALDTVLALEDAVDWNPGDEVVIISGTGVKGAKPMEEIVTVETVQDTD 2103
+ ++ C R + + VLA A N G + I + + V G + DT
Sbjct: 1947 KKELIECARRVSEKVSHVLAALQA--GNRGTQACITAASAVSG---------IIADLDTT 1995
Query: 2104 LYLKSPLRYSHNFTENWVAGEHHILKATVALLSRSITIQGNLTNEREKLLVSCQEANAPE 2163
+ + + TE + ILK L+ + + N +EKL + Q + A
Sbjct: 1996 IMFATAGTLNREGTETFADHREGILKTAKVLVEDTKVLVQNAAGSQEKLAQAAQSSVATI 2055
Query: 2164 GNLQHCLYSMSEKMLGSRDMGARVIV 2189
L + + LG+ D +V++
Sbjct: 2056 TRLAD-VVKLGAASLGAEDPETQVVL 2080
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 136,599,598
Number of Sequences: 37866
Number of extensions: 6454492
Number of successful extensions: 12966
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 12576
Number of HSP's gapped (non-prelim): 193
length of query: 3396
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3275
effective length of database: 13,665,732
effective search space: 44755272300
effective search space used: 44755272300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.