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Search of human proteins with 42544132
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
(586 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 1210 0.0
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 849 0.0
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 753 0.0
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 735 0.0
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 652 0.0
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 644 0.0
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 644 0.0
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 628 e-180
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 592 e-169
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 592 e-169
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 429 e-120
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 186 5e-47
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 182 6e-46
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 174 3e-43
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 162 1e-39
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 130 3e-30
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 130 3e-30
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 101 2e-21
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 75 2e-13
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 73 6e-13
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 67 5e-11
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 67 5e-11
gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo... 60 4e-09
gi|57165412 acyl-CoA synthetase long-chain family member 6 isofo... 59 2e-08
gi|57165410 acyl-CoA synthetase long-chain family member 6 isofo... 59 2e-08
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 58 3e-08
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 53 7e-07
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 53 7e-07
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 51 3e-06
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 51 3e-06
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 1210 bits (3131), Expect = 0.0
Identities = 586/586 (100%), Positives = 586/586 (100%)
Query: 1 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF 60
MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
Sbjct: 1 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF 60
Query: 61 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG 120
AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
Sbjct: 61 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG 120
Query: 121 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA 180
DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
Sbjct: 121 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA 180
Query: 181 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG 240
VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
Sbjct: 181 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG 240
Query: 241 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT 300
YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
Sbjct: 241 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT 300
Query: 301 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV 360
HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
Sbjct: 301 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV 360
Query: 361 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPG 420
TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPG
Sbjct: 361 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPG 420
Query: 421 QEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDV 480
QEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDV
Sbjct: 421 QEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWFVARADDV 480
Query: 481 ILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIK 540
ILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIK
Sbjct: 481 ILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIK 540
Query: 541 EIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWKTI 586
EIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWKTI
Sbjct: 541 EIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWKTI 586
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 849 bits (2194), Expect = 0.0
Identities = 408/409 (99%), Positives = 409/409 (100%)
Query: 1 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF 60
MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF
Sbjct: 1 MLARVTRKMLRHAKCFQRLAIFGSVRALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNF 60
Query: 61 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG 120
AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG
Sbjct: 61 AKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRG 120
Query: 121 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA 180
DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA
Sbjct: 121 DRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPA 180
Query: 181 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG 240
VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG
Sbjct: 181 VDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSG 240
Query: 241 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT 300
YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT
Sbjct: 241 YPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFT 300
Query: 301 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV 360
HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV
Sbjct: 301 HHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDV 360
Query: 361 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKI 409
TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVK+
Sbjct: 361 TEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKV 409
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 753 bits (1944), Expect = 0.0
Identities = 343/559 (61%), Positives = 446/559 (79%), Gaps = 1/559 (0%)
Query: 26 RALHKDNRTATPQNFSNYESMKQDFKLGIPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWW 85
R LHKD++ TP +++E++ + + +P+ FNFA DVLDQW+ KEK G++P+NPA WW
Sbjct: 21 RRLHKDHQLWTPLTLADFEAINRCNR-PLPKNFNFAADVLDQWSQKEKTGERPANPALWW 79
Query: 86 INRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGT 145
+N G+E++WSF ELGSLSRK AN+L++ C LQRGDR+ +ILPR+PEWWL NVAC+RTG
Sbjct: 80 VNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGI 139
Query: 146 VLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAVASKCENLHSKLIVSENSREGW 205
+ +PGT QLT KDILYRL++SKA CI+ ++ +APAV+++ +C +L +KL+VS S GW
Sbjct: 140 IFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGW 199
Query: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265
+ +EL + AS+ H+CV+T E M I+FTSGT+G+PKM H+ SS G+G ++ GR+WLD
Sbjct: 200 LSFQELFQFASEEHSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLD 259
Query: 266 LTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCS 325
L SD++WN SDTGW K+A SVFS W+ GACVF H + +F+ + L TL+ YPIT CS
Sbjct: 260 LKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCS 319
Query: 326 APTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLIC 385
PTVYRMLVQ D+ YKFKSL+HC++ GEP+ P+V E+WR +TGL++YEGYGQTE +IC
Sbjct: 320 PPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMIC 379
Query: 386 GNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNP 445
N KG +IKPGSMGK +DV+I+D NGNVLPPG+EG+I +++ P RPF F+ YVDNP
Sbjct: 380 ANQKGQEIKPGSMGKGMLPYDVQIIDENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNP 439
Query: 446 SKTASTLRGNFYITGDRGYMDKDGYFWFVARADDVILSSGYRIGPFEVENALNEHPSVAE 505
KTA+T+RG+FY+TGDRG MD DGYFWFV RADDVI+SSGYRIGPFEVE+AL EHP+V E
Sbjct: 440 QKTAATIRGDFYVTGDRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVE 499
Query: 506 SAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQEL 565
SAVVSSPD IRGEVVKAFVVL +KS++ E+L E+Q+HVKK+TAPYKYPRKVEF+QEL
Sbjct: 500 SAVVSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQEL 559
Query: 566 PKTISGKTKRNELRKKEWK 584
PKTI+GK KRN LR +EW+
Sbjct: 560 PKTITGKIKRNVLRDQEWR 578
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 735 bits (1897), Expect = 0.0
Identities = 331/530 (62%), Positives = 426/530 (80%), Gaps = 1/530 (0%)
Query: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
+PEYFNFA DVLD W+ E+AG +P NPAFWW+N G E++WSFEELG SRK AN+L
Sbjct: 49 VPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGG 108
Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
AC LQ GDR++L+LPR+PEWWL +VAC+RTGTV+IPG TQLT+KD+ YRLQ+S+A IIT
Sbjct: 109 ACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIIT 168
Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
+D LAP VDA++++C +L +KL+VS++SR GW N +EL++ AS H C++TK + +AI+
Sbjct: 169 SDSLAPRVDAISAECPSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSRDPLAIY 228
Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
FTSGT+G PKM H+ SS+GLG +GR W+ LT SD+ WNT+DTGW K+AW+ +FS W
Sbjct: 229 FTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDIFWNTTDTGWVKAAWT-LFSAWP 287
Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
G+C+F H LPR + IL TLSK+PIT C PT++R+LVQ D+T Y+F+SL+HC++ G
Sbjct: 288 NGSCIFVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGG 347
Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413
E + PDV EKW+++TG+++YEGYGQ+ETV+IC N KGMKIK GSMGK SP +DV+IVD
Sbjct: 348 EALNPDVREKWKHQTGVELYEGYGQSETVVICANPKGMKIKSGSMGKASPPYDVQIVDDE 407
Query: 414 GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWF 473
GNVLPPG+EG++ +++ P RPF F Y+DNP KTA++ +G+FYITGDR MDKDGYFWF
Sbjct: 408 GNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWF 467
Query: 474 VARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSH 533
+ R DDVI SS YRIGP EVE+AL EHP+V ESAVVSSPDPIRGEVVKAF+VL P Y SH
Sbjct: 468 MGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSH 527
Query: 534 DQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEW 583
D E L +E+QEHVK+ TAPYKYPRKV F+ ELPKT+SGK +R++LR +EW
Sbjct: 528 DPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEW 577
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 652 bits (1682), Expect = 0.0
Identities = 309/531 (58%), Positives = 384/531 (72%), Gaps = 1/531 (0%)
Query: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
+P FNFA DVLD W D EKAGK+ +PA WW+N G+E+ W+F EL S++ AN+LS
Sbjct: 40 VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99
Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
AC LQRGDRV ++LPRVPEWWL + C+R G + +PGT Q+ DILYRLQ SKA I+
Sbjct: 100 ACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159
Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
D + VD VAS+C +L KL+VSE S +GW N K+L+ AS +H CV+T E AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219
Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
FTSGTSG PKM H++SS GL ++ W L SD+MW SDTGW + S+ PW
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILCSLMEPWA 278
Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
GAC F H LP+F+P IL+TLS YPI AP VYRML+Q D++SYKF L++CV+ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVG 338
Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413
E + P+ E WR +TGLDI E YGQTET L C K MKIKPG MG + +DV+I+D
Sbjct: 339 ESLLPETLENWRAQTGLDIRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIIDDK 398
Query: 414 GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWF 473
GNVLPPG EGDIGI+V P RP G+F+ YVDNP KTA+ +RG+F++ GDRG D+DGYF F
Sbjct: 399 GNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQF 458
Query: 474 VARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSH 533
+ RADD+I SSGYRIGP EVENAL EHP+V E+AV+SSPDP+RGEVVKAFVVL + SH
Sbjct: 459 MGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSH 518
Query: 534 DQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWK 584
D EQL KE+Q+HVK TAPYKYPRK+EF+ LPKT++GK +R +LR KEWK
Sbjct: 519 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWK 569
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 644 bits (1660), Expect = 0.0
Identities = 304/531 (57%), Positives = 383/531 (72%), Gaps = 1/531 (0%)
Query: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
+P FNFA DVLD W D EKAGK+ +PA WW+N G+E+ W+F EL S++ ANILS
Sbjct: 40 VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANILSG 99
Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
AC LQRGDRV ++LPRVPEWWL + C+R G + +PGT Q+ DILYRLQ SKA I+
Sbjct: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159
Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
D + VD VAS+C +L KL+VSE S +GW N K+L+ AS +H CV+T E AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219
Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
FTSGTSG PKM H++SS GL ++ W L SD+MW SDTGW + S+ W
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278
Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
GAC F H LP+F+P IL+TLS YPI AP VYRML+Q D++SYKF L++C++ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338
Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413
E + P+ E WR +TGLDI E YGQTET L C K MKIKPG MG + +DV+++D
Sbjct: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIDDK 398
Query: 414 GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWF 473
GNVLPPG EGDIGI+V P RP G+F+ YV+NP KTA+ +RG+F++ GDRG D+DGYF F
Sbjct: 399 GNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQF 458
Query: 474 VARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSH 533
+ RADD+I SSGYRIGP EVENAL +HP+V E+AV+SSPDP+RGEVVKAFV+L + SH
Sbjct: 459 MGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSH 518
Query: 534 DQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWK 584
D EQL KE+Q+HVK TAPYKYPRK+EF+ LPKT++GK +R +LR KEWK
Sbjct: 519 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEWK 569
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 644 bits (1660), Expect = 0.0
Identities = 304/531 (57%), Positives = 383/531 (72%), Gaps = 1/531 (0%)
Query: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
+P FNFA DVLD W D EKAGK+ +PA WW+N G+E+ W+F EL S++ ANILS
Sbjct: 40 VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANILSG 99
Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
AC LQRGDRV ++LPRVPEWWL + C+R G + +PGT Q+ DILYRLQ SKA I+
Sbjct: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159
Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
D + VD VAS+C +L KL+VSE S +GW N K+L+ AS +H CV+T E AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219
Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
FTSGTSG PKM H++SS GL ++ W L SD+MW SDTGW + S+ W
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278
Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
GAC F H LP+F+P IL+TLS YPI AP VYRML+Q D++SYKF L++C++ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338
Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413
E + P+ E WR +TGLDI E YGQTET L C K MKIKPG MG + +DV+++D
Sbjct: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIDDK 398
Query: 414 GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWF 473
GNVLPPG EGDIGI+V P RP G+F+ YV+NP KTA+ +RG+F++ GDRG D+DGYF F
Sbjct: 399 GNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQF 458
Query: 474 VARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSH 533
+ RADD+I SSGYRIGP EVENAL +HP+V E+AV+SSPDP+RGEVVKAFV+L + SH
Sbjct: 459 MGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSH 518
Query: 534 DQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWK 584
D EQL KE+Q+HVK TAPYKYPRK+EF+ LPKT++GK +R +LR KEWK
Sbjct: 519 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEWK 569
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 628 bits (1620), Expect = e-180
Identities = 299/532 (56%), Positives = 385/532 (72%), Gaps = 6/532 (1%)
Query: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
+PE FNFA VLD W KEK GK+ NPAFWW+N G+E++WSF E+G L+R+ AN+ ++
Sbjct: 45 VPEEFNFASYVLDYWAQKEKEGKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQ 104
Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
C LQ+GD + L+LPRVPEWWL V C+RTG + IP T L KDILYRLQ SKA I+T
Sbjct: 105 TCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVT 164
Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
D LA VD++AS+C +L +KL+VS++SREGW + + L+K AS HTCVK+K + M IF
Sbjct: 165 IDALASEVDSIASQCPSLKTKLLVSDHSREGWLDFRSLVKSASPEHTCVKSKTLDPMVIF 224
Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVN---GRFWLDLTPSDVMWNTSDTGWAKSAWSSVFS 290
FTSGT+G+PKM H+H GL L + R L SDV W SD+GW + ++
Sbjct: 225 FTSGTTGFPKMAKHSH---GLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVE 281
Query: 291 PWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCV 350
PW G VF HHLP+F+ I+QTL KYPI F ++YRM++Q D TS +F +L+HC
Sbjct: 282 PWTAGCTVFIHHLPQFDTKVIIQTLLKYPINHFWGVSSIYRMILQQDFTSIRFPALEHCY 341
Query: 351 SAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIV 410
+ GE + P E+W+ +TGL +YE YGQ+ET LIC + GMKIKPG MGK +P +DV+++
Sbjct: 342 TGGEVVLPKDQEEWKRRTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVI 401
Query: 411 DVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGY 470
D G++LPP EG+IGI++ P RP LF Y +P KTA G+FY TGDRG MD++GY
Sbjct: 402 DDKGSILPPNTEGNIGIRIKPVRPVSLFMCYEGDPEKTAKVECGDFYNTGDRGKMDEEGY 461
Query: 471 FWFVARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDY 530
F+ R+DD+I +SGYRIGP EVE+AL EHP+VAESAVV SPDPIRGEVVKAF+VL P +
Sbjct: 462 ICFLGRSDDIINASGYRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQF 521
Query: 531 KSHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKE 582
SHD++QL KE+Q+HVK TAPYKYPRKVEF+ ELPKTI+GK +R ELRKKE
Sbjct: 522 LSHDKDQLTKELQQHVKSVTAPYKYPRKVEFVSELPKTITGKIERKELRKKE 573
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 592 bits (1526), Expect = e-169
Identities = 286/531 (53%), Positives = 364/531 (68%), Gaps = 7/531 (1%)
Query: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
+P FNFA DVLD W D EKAGK+ +PA WW+N G+E+ W+F EL S++ AN+LS
Sbjct: 40 VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99
Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
AC LQRGDRV ++LPRVPEWWL + C+R G + +PGT Q+ DILYRLQ SKA I+
Sbjct: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159
Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
D + VD VAS+C +L KL+VSE S +GW N K+L+ AS +H CV+T E AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219
Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
FTSGTSG PKM H++SS GL ++ W L SD+MW SDTGW + S+ W
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278
Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
GAC F H LP+F+P IL+TLS YPI AP VYRML+Q D++SYKF L++C++ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338
Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413
E + P+ E WR +TGLDI E YGQTET L C K MKIKPG MG + +DV+++
Sbjct: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIAFV 398
Query: 414 GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWF 473
G G G L F + +NP KTA+ +RG+F++ GDRG D+DGYF F
Sbjct: 399 HGSPRAGDLGFAGTMTLS------FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQF 452
Query: 474 VARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSH 533
+ RADD+I SSGYRIGP EVENAL +HP+V E+AV+SSPDP+RGEVVKAFV+L + SH
Sbjct: 453 MGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSH 512
Query: 534 DQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWK 584
D EQL KE+Q+HVK TAPYKYPRK+EF+ LPKT++GK +R +LR KEWK
Sbjct: 513 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEWK 563
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 592 bits (1526), Expect = e-169
Identities = 286/531 (53%), Positives = 364/531 (68%), Gaps = 7/531 (1%)
Query: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
+P FNFA DVLD W D EKAGK+ +PA WW+N G+E+ W+F EL S++ AN+LS
Sbjct: 40 VPAKFNFASDVLDHWADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANVLSG 99
Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
AC LQRGDRV ++LPRVPEWWL + C+R G + +PGT Q+ DILYRLQ SKA I+
Sbjct: 100 ACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA 159
Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
D + VD VAS+C +L KL+VSE S +GW N K+L+ AS +H CV+T E AI+
Sbjct: 160 GDEVIQEVDTVASECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIY 219
Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
FTSGTSG PKM H++SS GL ++ W L SD+MW SDTGW + S+ W
Sbjct: 220 FTSGTSGLPKMAEHSYSSLGLKAKMDAG-WTGLQASDIMWTISDTGWILNILGSLLESWT 278
Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAG 353
GAC F H LP+F+P IL+TLS YPI AP VYRML+Q D++SYKF L++C++ G
Sbjct: 279 LGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGG 338
Query: 354 EPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413
E + P+ E WR +TGLDI E YGQTET L C K MKIKPG MG + +DV+++
Sbjct: 339 ESLLPETLENWRAQTGLDIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIAFV 398
Query: 414 GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFWF 473
G G G L F + +NP KTA+ +RG+F++ GDRG D+DGYF F
Sbjct: 399 HGSPRAGDLGFAGTMTLS------FCGHQENPDKTAANIRGDFWLLGDRGIKDEDGYFQF 452
Query: 474 VARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSH 533
+ RADD+I SSGYRIGP EVENAL +HP+V E+AV+SSPDP+RGEVVKAFV+L + SH
Sbjct: 453 MGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSH 512
Query: 534 DQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKKEWK 584
D EQL KE+Q+HVK TAPYKYPRK+EF+ LPKT++GK +R +LR KEWK
Sbjct: 513 DPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKEWK 563
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 429 bits (1102), Expect = e-120
Identities = 206/436 (47%), Positives = 290/436 (66%), Gaps = 1/436 (0%)
Query: 54 IPEYFNFAKDVLDQWTDKEKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSE 113
+ + FNFAKDVLDQW+ EK G + PA W ++ GEE +WSFE + LS+K A+ILS+
Sbjct: 45 VSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSD 104
Query: 114 ACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIIT 173
C+L GDR+++ILP PE + +AC+R G +PG+ QLT K I Y+L+ SKA CI+
Sbjct: 105 TCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGSPQLTAKKIRYQLRMSKAQCIVA 164
Query: 174 NDVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIF 233
N+ +AP V++ S C L +KL+VS+ S +GW + K+L++ A T ++TK + MAIF
Sbjct: 165 NEAMAPVVNSAVSDCPTLKTKLLVSDKSYDGWLDFKKLIQVAPPKQTYMRTKSQDPMAIF 224
Query: 234 FTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWI 293
FT GT+G PKM ++ G+G S R W+DL P+DV+W+ D + S+V W
Sbjct: 225 FTKGTTGAPKMVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWF 284
Query: 294 QGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQND-ITSYKFKSLKHCVSA 352
QGACVF H+P F P ++L LS++PIT + P +Y+ L+Q+ TSY+FKSLK CV+A
Sbjct: 285 QGACVFLCHMPTFCPETVLNVLSRFPITTLSANPEMYQELLQHKCFTSYRFKSLKQCVAA 344
Query: 353 GEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKIVDV 412
G PI+P V E W+ T LDIYEGYGQTET L+C K +K+KP S+GKP P + V+IVD
Sbjct: 345 GGPISPGVIEDWKRITKLDIYEGYGQTETGLLCATSKTIKLKPSSLGKPLPPYIVQIVDE 404
Query: 413 NGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDKDGYFW 472
N N+LPPG+EG+I I++ N+P L+ ++ + + AS Y+TGDRG MD+DGYFW
Sbjct: 405 NSNLLPPGEEGNIAIRIKLNQPASLYCPHMVSWEEYASARGHMLYLTGDRGIMDEDGYFW 464
Query: 473 FVARADDVILSSGYRI 488
+ R DDV + G R+
Sbjct: 465 WSGRVDDVANALGQRL 480
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 186 bits (472), Expect = 5e-47
Identities = 159/578 (27%), Positives = 260/578 (44%), Gaps = 66/578 (11%)
Query: 59 NFAKDVLDQWTDKEKAGKKPSNPAFWWI-NRNGEEMRWSFEELGSLSRKFANILSEACSL 117
N +VLD+ ++K G K AF+W N GE + ++ +L +F+N+L + +
Sbjct: 102 NICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GI 157
Query: 118 QRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDV- 176
Q+GDRV + +P +PE +A +AC R G + + + + R+ S + +IT D
Sbjct: 158 QKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF 217
Query: 177 --------LAPAVDAVASKCEN----LHSKLIVSENSRE--GWGNLK------------- 209
L D KC+ + ++V R G G+
Sbjct: 218 YRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277
Query: 210 -------------ELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGL 256
ELM+ A D + + I +TSG++G PK HT + L +
Sbjct: 278 QISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYV 337
Query: 257 SVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGAC-VFTHHLPRFEPTSILQTL 315
+ ++ D DV W T+D GW + P GA V +P + + L ++
Sbjct: 338 ATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSI 397
Query: 316 -SKYPITVFCSAPTVYRMLVQ---NDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLD 371
KY +T F +APT R+L++ +T + SL+ + GEPI P+ + G
Sbjct: 398 VDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQ 457
Query: 372 ---IYEGYGQTETV--LICGNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPGQEGDIG 426
I + + QTET ++ +KPGS P I++ +G L EG+
Sbjct: 458 RCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEEL----EGEAE 513
Query: 427 IQVLPNRPF-GLFTHYVDNPSKTASTLRGNF---YITGDRGYMDKDGYFWFVARADDVIL 482
++ +P+ G+ N + +T F Y+TGD D+DGY+W R DD++
Sbjct: 514 GYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLN 573
Query: 483 SSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEI 542
SG+ + EVE+AL EH +VAE+AVV P P++GE + FV L + +L +E+
Sbjct: 574 VSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTF--SPKLTEEL 631
Query: 543 QEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRK 580
++ +++ P P ++ LPKT SGK R LRK
Sbjct: 632 KKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRK 669
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 182 bits (463), Expect = 6e-46
Identities = 160/591 (27%), Positives = 261/591 (44%), Gaps = 79/591 (13%)
Query: 59 NFAKDVLDQWTDKEKAGKKPSNPAFWWI-NRNGEEMRWSFEELGSLSRKFANILSEACSL 117
N +VLD+ ++K G K AF+W N GE + ++ +L +F+N+L + +
Sbjct: 102 NICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GI 157
Query: 118 QRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDV- 176
Q+GDRV + +P +PE +A +AC R G + + + + R+ S + +IT D
Sbjct: 158 QKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF 217
Query: 177 --------LAPAVDAVASKCEN----LHSKLIVSENSR--------------------EG 204
L D KC+ + ++V R +
Sbjct: 218 YRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277
Query: 205 WGNLKE---------------------LMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPK 243
G LKE LM+ A D + + I +TSG++G PK
Sbjct: 278 QGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPK 337
Query: 244 MTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGAC-VFTHH 302
HT + L ++ ++ D DV W T+D GW + P GA V
Sbjct: 338 GVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEG 397
Query: 303 LPRFEPTSILQTL-SKYPITVFCSAPTVYRMLVQ---NDITSYKFKSLKHCVSAGEPITP 358
+P + + L ++ KY +T F +APT R+L++ +T + SL+ + GEPI P
Sbjct: 398 IPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINP 457
Query: 359 DVTEKWRNKTGLD---IYEGYGQTETV--LICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413
+ + G I + + QTET ++ +KPGS P I++ +
Sbjct: 458 EAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNES 517
Query: 414 GNVLPPGQEGDIGIQVLPNRPF-GLFTHYVDNPSKTASTLRGNF---YITGDRGYMDKDG 469
G L EG+ ++ +P+ G+ N + +T F Y+TGD D+DG
Sbjct: 518 GEEL----EGEAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDG 573
Query: 470 YFWFVARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPD 529
Y+W R DD++ SG+ + EVE+AL EH +VAE+AVV P P++GE + FV L
Sbjct: 574 YYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDG 633
Query: 530 YKSHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRK 580
+ +L +E+++ +++ P P ++ LPKT SGK R LRK
Sbjct: 634 HTF--SPKLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRK 682
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 174 bits (440), Expect = 3e-43
Identities = 153/567 (26%), Positives = 251/567 (44%), Gaps = 45/567 (7%)
Query: 49 DFKLGIPEYF-----NFAKDVLDQWTDKEKAGKKPSNPAFWWI-NRNGEEMRWSFEELGS 102
DF G +F N + + LDQ K P + A W + G E+R ++ EL
Sbjct: 94 DFSTGKIGWFLGGQLNVSVNCLDQ-----HVRKSPESVALIWERDEPGTEVRITYRELLE 148
Query: 103 LSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYR 162
+ + AN L + RGDRV + +P P A +AC R G V + + + R
Sbjct: 149 TTCRLANTLKRH-GVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGR 207
Query: 163 LQSSKANCIITNDV---------LAPAVDAVASKCENLHSKLIVSE-NSREGWGNLKELM 212
+ +K +IT + L VD C + L+ +++ G+L +
Sbjct: 208 INDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPL 267
Query: 213 KH--ASDSHTCVKTK--HNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
+ A + C +++ + +TSG++G PK HT + + L ++ + D P
Sbjct: 268 EQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQP 327
Query: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTS--ILQTLSKYPITVFCSA 326
D+ +D GW V+ P GA P + +T+ + I F A
Sbjct: 328 GDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGA 387
Query: 327 PTVYRMLVQND---ITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLD----IYEGYGQT 379
PT R+L++ + Y SL+ S GEPI + E W ++ D + + + QT
Sbjct: 388 PTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWE-WLHRVVGDSRCTLVDTWWQT 446
Query: 380 ETVLIC----GNFKGMKIKPGSMGKPSPAFDVKIVDVNGNVLPPGQEGDIGIQVLPNRPF 435
ET IC + +G +I P +P ++D G+V+ G + + P
Sbjct: 447 ETGGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSVVE-GSNVSGALCISQAWPG 505
Query: 436 GLFTHYVDNPSKTASTLRG--NFYITGDRGYMDKDGYFWFVARADDVILSSGYRIGPFEV 493
T Y D+ + + +Y TGD Y + GY+ R DDVI SG+R+G E+
Sbjct: 506 MARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEI 565
Query: 494 ENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKTTAPY 553
E+A+ +HP+V ESAV+ P I+GE AF+V+ + D + +++E++ V A Y
Sbjct: 566 EDAIADHPAVPESAVIGYPHDIKGEAAFAFIVVKD--SAGDSDVVVQELKSMVATKIAKY 623
Query: 554 KYPRKVEFIQELPKTISGKTKRNELRK 580
P ++ ++ LPKT SGK R LRK
Sbjct: 624 AVPDEILVVKRLPKTRSGKVMRRLLRK 650
>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
sapiens]
Length = 686
Score = 162 bits (409), Expect = 1e-39
Identities = 138/518 (26%), Positives = 226/518 (43%), Gaps = 40/518 (7%)
Query: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
++++E+ K A +L + +++GD V++ +P +P+ +AC R G +
Sbjct: 144 FTYKEVLEQVSKLAGVLVKH-GIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFGGF 202
Query: 155 TQKDILYRLQSSKANCIITNDV---------LAPAVDAVASKCENLHSKLIVSENSREGW 205
K++ R+ K ++T P V+ ++ K+++
Sbjct: 203 ASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHKPDKILIYNRPNMEA 262
Query: 206 GNL---------KELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGL 256
L +E+ K + SH CV + I +TSGT+G PK + + L
Sbjct: 263 VPLAPGRDLDWDEEMAK--AQSHDCVPVLSEHPLYILYTSGTTGLPKGVIRPTGGYAVML 320
Query: 257 SVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQG-ACVFTHHLPRFEPTS--ILQ 313
+ L P +V W SD GW + P + G V P P + +
Sbjct: 321 HWSMSSIYGLQPGEVWWAASDLGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFR 380
Query: 314 TLSKYPITVFCSAPTVYRMLVQNDITS-----YKFKSLKHCVSAGEPITPDVTEKWRNKT 368
L+++ + +APT R + Q D + Y K AGE + E +N
Sbjct: 381 VLAEHGVAALFTAPTAIRAIRQQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSKNVF 440
Query: 369 GLDIYEGYGQTET----VLICGNFKGMKIKP-GSMGKPSPAFDVKIVDVNGNVLPPGQEG 423
+ + + + QTET C K P G GK P ++V I+D N L G
Sbjct: 441 RVPVLDHWWQTETGSPITASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCLG 500
Query: 424 DIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNF---YITGDRGYMDKDGYFWFVARADDV 480
+I ++ LP P G F+ N F Y T D GYMD++GY + ++R DDV
Sbjct: 501 NIVVK-LPLPP-GAFSGLWKNQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDV 558
Query: 481 ILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQLIK 540
I +G+RI +E ++ H +VA+ AVV DP++G V A VL D + +EQ+++
Sbjct: 559 INVAGHRISAGAIEESILSHGTVADCAVVGKEDPLKGHVPLALCVLRKDINA-TEEQVLE 617
Query: 541 EIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578
EI +HV++ P R F+++LPKT SGK R+ L
Sbjct: 618 EIVKHVRQNIGPVAAFRNAVFVKQLPKTRSGKIPRSAL 655
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 130 bits (327), Expect = 3e-30
Identities = 134/531 (25%), Positives = 225/531 (42%), Gaps = 72/531 (13%)
Query: 94 RWSFEELGSLSRKFANILSEACSLQRGD----RVILILPRVPEWWLANVACLRTGTVLIP 149
R ++ EL S S + + + C GD RV + + +A A +G V +P
Sbjct: 65 RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124
Query: 150 GTTQLTQKDILYRLQSSKANCIITN----DVLAPAVDAVASKCENLHSKLIVSENSREGW 205
+ + Y + S+++ ++ + ++L+P V + L +
Sbjct: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGA------ 178
Query: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265
++ ++ + N+ I +TSGT+G PK TH + ++ W
Sbjct: 179 ------VEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA- 231
Query: 266 LTPSDVMWNTSDTGWAKSAWSSVFSP-WIQGACVFTHHLPRFEPTSILQTL--SKYP-IT 321
T DV+ + +++ P W+ CV +P F P + + S+ P I
Sbjct: 232 WTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRIN 288
Query: 322 VFCSAPTVYRMLV------------QNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG 369
VF + PT+Y L+ Q+ + + + ++ VS + V EKW+N TG
Sbjct: 289 VFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITG 348
Query: 370 LDIYEGYGQTET-VLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN--------------- 413
+ E YG TE + + G PGS+G P P V+IV N
Sbjct: 349 HTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGD 408
Query: 414 --GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTAS--TLRGNFYITGDRGYMDKDG 469
G + PG E G ++L P +F Y + P +T S TL G ++ TGD + KDG
Sbjct: 409 ERGTKVTPGFEEKEG-ELLVRGP-SVFREYWNKPEETKSAFTLDG-WFKTGDT-VVFKDG 464
Query: 470 YFWFVARAD-DVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNP 528
+W R D+I + GY++ EVE L HPS+ + AV+ PD G+ V A V L
Sbjct: 465 QYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLRE 524
Query: 529 DYK-SHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578
+ SH +E++E + APY P ++ ++E+P+ GK + L
Sbjct: 525 GHSLSH------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 130 bits (327), Expect = 3e-30
Identities = 134/531 (25%), Positives = 225/531 (42%), Gaps = 72/531 (13%)
Query: 94 RWSFEELGSLSRKFANILSEACSLQRGD----RVILILPRVPEWWLANVACLRTGTVLIP 149
R ++ EL S S + + + C GD RV + + +A A +G V +P
Sbjct: 65 RHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVP 124
Query: 150 GTTQLTQKDILYRLQSSKANCIITN----DVLAPAVDAVASKCENLHSKLIVSENSREGW 205
+ + Y + S+++ ++ + ++L+P V + L +
Sbjct: 125 LYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGA------ 178
Query: 206 GNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLD 265
++ ++ + N+ I +TSGT+G PK TH + ++ W
Sbjct: 179 ------VEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWA- 231
Query: 266 LTPSDVMWNTSDTGWAKSAWSSVFSP-WIQGACVFTHHLPRFEPTSILQTL--SKYP-IT 321
T DV+ + +++ P W+ CV +P F P + + S+ P I
Sbjct: 232 WTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVM---MPEFSPQQVWEKFLSSETPRIN 288
Query: 322 VFCSAPTVYRMLV------------QNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG 369
VF + PT+Y L+ Q+ + + + ++ VS + V EKW+N TG
Sbjct: 289 VFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITG 348
Query: 370 LDIYEGYGQTET-VLICGNFKGMKIKPGSMGKPSPAFDVKIVDVN--------------- 413
+ E YG TE + + G PGS+G P P V+IV N
Sbjct: 349 HTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGD 408
Query: 414 --GNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTAS--TLRGNFYITGDRGYMDKDG 469
G + PG E G ++L P +F Y + P +T S TL G ++ TGD + KDG
Sbjct: 409 ERGTKVTPGFEEKEG-ELLVRGP-SVFREYWNKPEETKSAFTLDG-WFKTGDT-VVFKDG 464
Query: 470 YFWFVARAD-DVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNP 528
+W R D+I + GY++ EVE L HPS+ + AV+ PD G+ V A V L
Sbjct: 465 QYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLRE 524
Query: 529 DYK-SHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578
+ SH +E++E + APY P ++ ++E+P+ GK + L
Sbjct: 525 GHSLSH------RELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKAL 569
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 101 bits (251), Expect = 2e-21
Identities = 124/525 (23%), Positives = 221/525 (42%), Gaps = 46/525 (8%)
Query: 91 EEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPG 150
E++R +F +L K A+ L + L +GDR+ + P W L +A + G +L+
Sbjct: 96 EDVRLTFAQLKEEVDKAASGLL-SIGLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSV 154
Query: 151 TTQLTQKDILYRLQSSKANCII-----TNDVLAPAVDAVASKCENLHSKLIVSENSRE-- 203
++ Y L+ ++ + + + EN + S+ +
Sbjct: 155 NPAYQAMELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEVENAQPGALKSQRLPDLT 214
Query: 204 ----------GWGNLKELMKHASDSHTCVKTKHNEIMA-------IFFTSGTSGYPKMTA 246
G L E++ S + ++N+ I FTSGT+G PK
Sbjct: 215 TVISVDAPLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGAT 274
Query: 247 HTHSSFGLGLSVNG-RFWL-DLTPSDV-MWNTSDTGWAKSAWSSVFSPWIQGACVFTHHL 303
+H + ++ G R L + TP + M + + + + GA +
Sbjct: 275 LSHYNIVNNSNILGERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLILAS- 333
Query: 304 PRFEPTSILQTLSKYPITVFCSAPTVY-RMLVQNDITSYKFKSLKHCVSAGEPITPDVTE 362
P F L+ +S+ T PT++ +L Q D +SY ++ V AG P P++
Sbjct: 334 PIFNGKKALEAISRERGTFLYGTPTMFVDILNQPDFSSYDISTMCGGVIAGSPAPPELIR 393
Query: 363 KWRNKTGL-DIYEGYGQTETVLIC-GNFKGMKI--KPGSMGKPSPAFDVKIVDVNGNVLP 418
NK + D+ YG TE + +F + K S+G+ P + +I+++ L
Sbjct: 394 AIINKINMKDLVVAYGTTENSPVTFAHFPEDTVEQKAESVGRIMPHTEARIMNMEAGTLA 453
Query: 419 P-GQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTL-RGNFYITGDRGYMDKDGYFWFVAR 476
G++ I R + + Y P KT + + +Y TGD M++ G+ V R
Sbjct: 454 KLNTPGELCI-----RGYCVMLGYWGEPQKTEEAVDQDKWYWTGDVATMNEQGFCKIVGR 508
Query: 477 ADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQE 536
+ D+I+ G I P E+E+ + HP V E VV D GE + A + L +E
Sbjct: 509 SKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDRMGEEICACIRL-----KDGEE 563
Query: 537 QLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKK 581
++EI+ K + +K P+ + F+ P TISGK ++ +LR++
Sbjct: 564 TTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 75.1 bits (183), Expect = 2e-13
Identities = 115/520 (22%), Positives = 202/520 (38%), Gaps = 49/520 (9%)
Query: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
W+F +L + S AN+ + GD V + L PE+ + + G L
Sbjct: 104 WTFAQLDAYSNAVANLFRQL-GFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNL 162
Query: 155 TQKDILYRLQSSKANCIITNDVLAPAVDAVASKCENLHSKLIVSENSREG----WGNLKE 210
++ + + L +S A +I + AV V+ K + EG L
Sbjct: 163 RREPLAFCLGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDP 222
Query: 211 LMKHASDSHTC-VKTKH-NEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
L+K AS + + +K ++ + +TSGT+G PK HS + ++ G +
Sbjct: 223 LLKEASTAPLAQIPSKGMDDRLFYIYTSGTTGLPKAAIVVHSRY-YRMAAFGHHAYRMQA 281
Query: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPT 328
+DV+++ + V I G V +F + KY TV
Sbjct: 282 ADVLYDCLPLYHSAGNIIGVGQCLIYGLTVVLRK--KFSASRFWDDCIKYNCTVVQYIGE 339
Query: 329 VYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGL-DIYEGYGQTETVLICGN 387
+ R L++ + + + ++ G + P + E++ + G+ I E YG TE N
Sbjct: 340 ICRYLLKQPVREAERRHRVR-LAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIAN 398
Query: 388 FKGMKIKPGSMGKPSP----AFDVKIVDVNGNVLP----------PGQEGDIGI---QVL 430
G K GS G S + +++V VN + + P Q G+ G+ Q+
Sbjct: 399 MDG---KVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQIN 455
Query: 431 PNRPFGLFTHYVDNPSKTASTLRGNF------YITGDRGYMDKDGYFWFVARADDVILSS 484
P F YV + + F Y++GD MD+ GY +F R+ D
Sbjct: 456 QQDPLRRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWR 515
Query: 485 GYRIGPFEVENALNEHPSVAESAVVSSPDP-IRGEVVKAFVVLNPDYKSHDQEQLI--KE 541
G + EVE L+ + AV P + G+ A V D L+
Sbjct: 516 GENVSTTEVEGVLSRLLGQTDVAVYGVAVPGVEGKAGMAAVA--------DPHSLLDPNA 567
Query: 542 IQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKK 581
I + ++K APY P + + ++ T + K ++ L+++
Sbjct: 568 IYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQKTRLQRE 607
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 73.2 bits (178), Expect = 6e-13
Identities = 109/524 (20%), Positives = 199/524 (37%), Gaps = 48/524 (9%)
Query: 90 GEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEW---WLANVACLRTGTV 146
G + W+F +L S AN L +A L GD + + E+ WL +A L
Sbjct: 97 GTDTHWTFRQLDEYSSSVANFL-QARGLASGDVAAIFMENRNEFVGLWLG-MAKLGVEAA 154
Query: 147 LIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAVASK--------CENLHSKLIVS 198
LI T L + +L+ L +S+A ++ +A A+ V + C V
Sbjct: 155 LI--NTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWEPGAVP 212
Query: 199 ENSREGWGNLKELMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSV 258
++ LK+ KH +C + + +TSGT+G PK HS + ++
Sbjct: 213 PSTEHLDPLLKDAPKHLP---SCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRY-YRMAA 268
Query: 259 NGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKY 318
+ + P+D++++ + + + G V +F + KY
Sbjct: 269 LVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRK--KFSASRFWDDCIKY 326
Query: 319 PITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGL-DIYEGYG 377
T+ + R L+ + + ++ G + + + ++ + + E YG
Sbjct: 327 NCTIVQYIGELCRYLLNQPPREAENQHQVR-MALGNGLRQSIWTNFSSRFHIPQVAEFYG 385
Query: 378 QTETVLICGNFKGMKIKPGSMGKP-SPAFDVKIVDVNGNVLP-------------PGQEG 423
TE GNF G + S + +++V VN + + PG+ G
Sbjct: 386 ATECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPG 445
Query: 424 DIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNF------YITGDRGYMDKDGYFWFVARA 477
+ +++ P F Y++ + + F Y+TGD MD+ GY +F R
Sbjct: 446 QLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRT 505
Query: 478 DDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPDYKSHDQEQ 537
D G + EVE L+ +A+ AV P V +P
Sbjct: 506 GDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGNCD---- 561
Query: 538 LIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRKK 581
++ + ++K Y P + + EL KT + K ++ ELRK+
Sbjct: 562 -LERFAQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKE 604
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 67.0 bits (162), Expect = 5e-11
Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 46/514 (8%)
Query: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
++++++ S + A++ SL++GD V L++ P++ + G V+ T +
Sbjct: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
Query: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213
+L +++ ++ D+L + + S EN+ S + ++ +G +LKE +
Sbjct: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198
Query: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
+ D SH V + + IF TSGT+G PK + G +V F T
Sbjct: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255
Query: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327
D+++ T + +A + GA CV +F + KY +TVF
Sbjct: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLKK---KFSASQFWSDCKKYDVTVFQYIG 312
Query: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386
+ R L + + K K ++ G I DV ++ ++ G + + E Y TE+ +
Sbjct: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371
Query: 387 NFKGMKIKPGSMGKPS------PAFDVKIVDVNGNV-----------LPPGQEGDIGIQV 429
N+ G + G++G+ + FD+ D + + G+ G + +V
Sbjct: 372 NYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRV 428
Query: 430 LPNRPF-GLFTHYVDNPSKTASTL--RGNFYI-TGDRGYMDKDGYFWFVARADDVILSSG 485
PF G Y K + +G+ Y+ TGD D+D + +F R D G
Sbjct: 429 NAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKG 488
Query: 486 YRIGPFEVENALNEHPSVAESAVVS-SPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQE 544
+ EV + + + E+ V + G A ++L P+ ++++ E
Sbjct: 489 ENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLD-----LEKVYE 543
Query: 545 HVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578
V Y PR + +++ T + K +++L
Sbjct: 544 QVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 67.0 bits (162), Expect = 5e-11
Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 46/514 (8%)
Query: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
++++++ S + A++ SL++GD V L++ P++ + G V+ T +
Sbjct: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
Query: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213
+L +++ ++ D+L + + S EN+ S + ++ +G +LKE +
Sbjct: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198
Query: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
+ D SH V + + IF TSGT+G PK + G +V F T
Sbjct: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255
Query: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327
D+++ T + +A + GA CV +F + KY +TVF
Sbjct: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLKK---KFSASQFWSDCKKYDVTVFQYIG 312
Query: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386
+ R L + + K K ++ G I DV ++ ++ G + + E Y TE+ +
Sbjct: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371
Query: 387 NFKGMKIKPGSMGKPS------PAFDVKIVDVNGNV-----------LPPGQEGDIGIQV 429
N+ G + G++G+ + FD+ D + + G+ G + +V
Sbjct: 372 NYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRV 428
Query: 430 LPNRPF-GLFTHYVDNPSKTASTL--RGNFYI-TGDRGYMDKDGYFWFVARADDVILSSG 485
PF G Y K + +G+ Y+ TGD D+D + +F R D G
Sbjct: 429 NAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKG 488
Query: 486 YRIGPFEVENALNEHPSVAESAVVS-SPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQE 544
+ EV + + + E+ V + G A ++L P+ ++++ E
Sbjct: 489 ENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLD-----LEKVYE 543
Query: 545 HVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578
V Y PR + +++ T + K +++L
Sbjct: 544 QVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
>gi|40807491 acyl-CoA synthetase long-chain family member 1 [Homo
sapiens]
Length = 698
Score = 60.5 bits (145), Expect = 4e-09
Identities = 53/179 (29%), Positives = 81/179 (45%), Gaps = 15/179 (8%)
Query: 350 VSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKI 409
V+ P++ V R G YEGYGQTE C G +G P P +K+
Sbjct: 432 VTGAAPVSATVLTFLRAALGCQFYEGYGQTECTAGCCLTMPGDWTAGHVGAPMPCNLIKL 491
Query: 410 VDVNG-NVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTL-RGNFYITGDRGYMDK 467
VDV N + EG++ ++ PN +F Y+ +P+KTA L + + TGD G
Sbjct: 492 VDVEEMNYMAAEGEGEVCVKG-PN----VFQGYLKDPAKTAEALDKDGWLHTGDIGKWLP 546
Query: 468 DGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVV 525
+G + R + L+ G I P ++EN VA+ V GE ++AF++
Sbjct: 547 NGTLKIIDRKKHIFKLAQGEYIAPEKIENIYMRSEPVAQVFV-------HGESLQAFLI 598
>gi|57165412 acyl-CoA synthetase long-chain family member 6 isoform
b [Homo sapiens]
Length = 722
Score = 58.5 bits (140), Expect = 2e-08
Identities = 56/201 (27%), Positives = 88/201 (43%), Gaps = 15/201 (7%)
Query: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGN 387
+++ L N I + ++ V+ P +P V R G +YEGYGQTE C
Sbjct: 435 SIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTF 494
Query: 388 FKGMKIKPGSMGKPSPAFDVKIVDVNG-NVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPS 446
G +G P P +K+VDV N EG+I ++ PN +F Y+ +P
Sbjct: 495 TTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRG-PN----VFKGYLKDPD 549
Query: 447 KTASTLRGNFYI-TGDRGYMDKDGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVA 504
+T L + ++ TGD G G + R + L+ G + P ++EN VA
Sbjct: 550 RTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVA 609
Query: 505 ESAVVSSPDPIRGEVVKAFVV 525
+ V G+ +KAF+V
Sbjct: 610 QIYV-------HGDSLKAFLV 623
Score = 34.7 bits (78), Expect = 0.25
Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 25/191 (13%)
Query: 76 KKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWL 135
+KP P W + +E+ E LGS +L C + + PEW +
Sbjct: 137 RKPKQPYQWL---SYQEVADRAEFLGS------GLLQHNCKACTDQFIGVFAQNRPEWII 187
Query: 136 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAV--DAVASKCENLHS 193
+AC V++P L I Y + ++ + +I + + + V K E
Sbjct: 188 VELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK-ETPGL 246
Query: 194 KLIV-----SENSREGWGNLKELMKHASDSHTCVKTKH--------NEIMAIFFTSGTSG 240
KLI+ E +E ++K C + H +++ + FTSGT+G
Sbjct: 247 KLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTG 306
Query: 241 YPKMTAHTHSS 251
PK TH +
Sbjct: 307 NPKGAMLTHGN 317
>gi|57165410 acyl-CoA synthetase long-chain family member 6 isoform
a [Homo sapiens]
Length = 722
Score = 58.5 bits (140), Expect = 2e-08
Identities = 56/201 (27%), Positives = 88/201 (43%), Gaps = 15/201 (7%)
Query: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGN 387
+++ L N I + ++ V+ P +P V R G +YEGYGQTE C
Sbjct: 435 SIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTF 494
Query: 388 FKGMKIKPGSMGKPSPAFDVKIVDVNG-NVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPS 446
G +G P P +K+VDV N EG+I ++ PN +F Y+ +P
Sbjct: 495 TTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRG-PN----VFKGYLKDPD 549
Query: 447 KTASTLRGNFYI-TGDRGYMDKDGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVA 504
+T L + ++ TGD G G + R + L+ G + P ++EN VA
Sbjct: 550 RTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVA 609
Query: 505 ESAVVSSPDPIRGEVVKAFVV 525
+ V G+ +KAF+V
Sbjct: 610 QIYV-------HGDSLKAFLV 623
Score = 34.7 bits (78), Expect = 0.25
Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 25/191 (13%)
Query: 76 KKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWL 135
+KP P W + +E+ E LGS +L C + + PEW +
Sbjct: 137 RKPKQPYQWL---SYQEVADRAEFLGS------GLLQHNCKACTDQFIGVFAQNRPEWII 187
Query: 136 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAV--DAVASKCENLHS 193
+AC V++P L I Y + ++ + +I + + + V K E
Sbjct: 188 VELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERK-ETPGL 246
Query: 194 KLIV-----SENSREGWGNLKELMKHASDSHTCVKTKH--------NEIMAIFFTSGTSG 240
KLI+ E +E ++K C + H +++ + FTSGT+G
Sbjct: 247 KLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTG 306
Query: 241 YPKMTAHTHSS 251
PK TH +
Sbjct: 307 NPKGAMLTHGN 317
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 57.8 bits (138), Expect = 3e-08
Identities = 115/499 (23%), Positives = 177/499 (35%), Gaps = 58/499 (11%)
Query: 114 ACSLQRGDRVILILPRVPE--WWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCI 171
A L G V L+LP PE W +A T +P T L + +L+ L+S A +
Sbjct: 208 AAPLSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVP--TALRRGPLLHCLRSCGARAL 265
Query: 172 ITNDVLAPAV------DAVASKCENLHSKLIVSENSREGWGNLKELMKHASDS----HTC 221
VLAP D A + LH G +L + D +
Sbjct: 266 ----VLAPEFLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLS 321
Query: 222 VKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWL-DLTPSDVMWNTSDTGW 280
+ FTSGT+G PK +H L G + L + DV++
Sbjct: 322 SPQSITDTCLYIFTSGTTGLPKAARISHLKI---LQCQGFYQLCGVHQEDVIYLALPLYH 378
Query: 281 AKSAWSSVFSPWIQGACVFTHHLPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITS 340
+ + GA V +F + ++ +TVF + R LV N S
Sbjct: 379 MSGSLLGIVGCMGIGATVVLK--SKFSAGQFWEDCQQHRVTVFQYIGELCRYLV-NQPPS 435
Query: 341 YKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICGNFKGMKIKPGSMG 399
+ K ++ G + PD E++ + G L + E YG TE + N+ G + G++G
Sbjct: 436 KAERGHKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQR---GAVG 492
Query: 400 KPS-----------PAFDV----KIVDVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDN 444
+ S +DV I D G+ + G+ G+ V P F Y
Sbjct: 493 RASWLYKHIFPFSLIRYDVTTGEPIRDPQGHCMAT-SPGEPGLLVAPVSQQSPFLGYAGG 551
Query: 445 PSKTASTLRGN-------FYITGDRGYMDKDGYFWFVARADDVILSSGYRIGPFEVENAL 497
P L + F+ TGD D G+ F R D G + EV
Sbjct: 552 PELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVF 611
Query: 498 NEHPSVAESAVVSSPDP-IRGEVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKTTAPYKYP 556
+ E V P G A +VL P + + ++ HV + PY P
Sbjct: 612 EALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALD-----LMQLYTHVSENLPPYARP 666
Query: 557 RKVEFIQELPKTISGKTKR 575
R + + L T + K ++
Sbjct: 667 RFLRLQESLATTETFKQQK 685
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 53.1 bits (126), Expect = 7e-07
Identities = 102/515 (19%), Positives = 204/515 (39%), Gaps = 53/515 (10%)
Query: 72 EKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVP 131
EKA + P P + + ++ ++ S + A L + L++GD V L++ P
Sbjct: 61 EKARQTPHKPFLLF-----RDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEP 115
Query: 132 EWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAV--ASKCE 189
+ + ++ G + + K +L+ Q A ++ + L AV+ + + K +
Sbjct: 116 AYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKD 175
Query: 190 NLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIM-----AIFFTSGTSGYPKM 244
++ + ++ +G + + + S + ++ +E+ +TSGT+G PK
Sbjct: 176 DVSIYYVSRTSNTDGIDSFLDKVDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKA 234
Query: 245 TAHTHSS--FGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHH 302
TH +G GL+ F L DV++ T + + + + GA +
Sbjct: 235 AMITHQRIWYGTGLT----FVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALR- 289
Query: 303 LPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTE 362
+F + KY +TV + R L N + K ++ G + DV
Sbjct: 290 -TKFSASQFWDDCRKYNVTVIQYIGELLRYLC-NSPQKPNDRDHKVRLALGNGLRGDVWR 347
Query: 363 KWRNKTG-LDIYEGYGQTETVLICGNFKGMKIKPGSMGKPS-----------PAFDVK-- 408
++ + G + IYE Y TE + F K G++G+ + +DV+
Sbjct: 348 QFVKRFGDICIYEFYAATEGNI---GFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKD 404
Query: 409 --IVDVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTAST------LRGNFYI-T 459
+ D NG + +G++G+ V F Y ++T +G+ Y +
Sbjct: 405 EPVRDENGYCVRV-PKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNS 463
Query: 460 GDRGYMDKDGYFWFVARADDVILSSGYRIGPFEVENALNEHPSVAESAV--VSSPDPIRG 517
GD +D + + +F R D G + EV + + V E V V PD G
Sbjct: 464 GDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDH-EG 522
Query: 518 EVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKTTAP 552
+ A + + +++ D ++L + I +++ P
Sbjct: 523 RIGMASIKMKENHE-FDGKKLFQHIADYLPSYARP 556
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 53.1 bits (126), Expect = 7e-07
Identities = 106/456 (23%), Positives = 181/456 (39%), Gaps = 56/456 (12%)
Query: 159 ILYRLQSSKANCIITNDVLAPAVDAVASK--CENLHSKLIVSENSREGWGNLKELMKHAS 216
+ + + SS A ++ + L +++ + K EN+ + + G G L + A+
Sbjct: 213 LAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD-AA 271
Query: 217 DSHTCVKTKHNEIM----AIF-FTSGTSGYPKMTAHTHS---SFGLGLSVNGRFWLDLTP 268
SH I A+F +TSGT+G PK TH LS++G T
Sbjct: 272 PSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGA-----TA 326
Query: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327
DV++ + GA CV P+F + ++ +TV
Sbjct: 327 DDVVYTVLPLYHVMGLVVGILGCLDLGATCVLA---PKFSTSCFWDDCRQHGVTVILYVG 383
Query: 328 TVYRMLVQNDITSYKFKSLKHCV--SAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLI 384
+ R L + + H V + G + DV E ++ + G + I+E YG TE +
Sbjct: 384 ELLRYLCN---IPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMG 440
Query: 385 CGNFKGMKIKPGSMGKPS-----------PAFDVK----IVDVNGNVLPPG--QEGDIGI 427
N+ G + G++GK S FD++ + D G +P G + G +
Sbjct: 441 LVNYVG---RCGALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLT 497
Query: 428 QVLPNRPF-GLFTHYVDNPSKTASTLRGN---FYITGDRGYMDKDGYFWFVARADDVILS 483
+V+ +PF G + K +R + +Y TGD MD++G+ +F R D
Sbjct: 498 KVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRW 557
Query: 484 SGYRIGPFEVENALNEHPSVAESAVVSSPDP-IRGEVVKAFVVLNPDYKSHDQEQLIKEI 542
G + EVE L++ + + V P G+V A V L P ++ D E+L
Sbjct: 558 KGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPG-QTFDGEKL---- 612
Query: 543 QEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578
+HV+ Y P + + T + K + L
Sbjct: 613 YQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRL 648
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 51.2 bits (121), Expect = 3e-06
Identities = 44/159 (27%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 350 VSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKI 409
V+ P++ V +R G +YE YGQTE C G +G P VK+
Sbjct: 417 VTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKL 476
Query: 410 VDV-NGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYI-TGDRGYMDK 467
DV + N EG++ I + +F Y+ +P KT L + ++ TGD G
Sbjct: 477 EDVADMNYFTVNNEGEVCI-----KGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLP 531
Query: 468 DGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVAE 505
+G + R ++ L+ G I P ++EN N V +
Sbjct: 532 NGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQ 570
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 51.2 bits (121), Expect = 3e-06
Identities = 44/159 (27%), Positives = 69/159 (43%), Gaps = 8/159 (5%)
Query: 350 VSAGEPITPDVTEKWRNKTGLDIYEGYGQTETVLICGNFKGMKIKPGSMGKPSPAFDVKI 409
V+ P++ V +R G +YE YGQTE C G +G P VK+
Sbjct: 417 VTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKL 476
Query: 410 VDV-NGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTASTLRGNFYI-TGDRGYMDK 467
DV + N EG++ I + +F Y+ +P KT L + ++ TGD G
Sbjct: 477 EDVADMNYFTVNNEGEVCI-----KGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLP 531
Query: 468 DGYFWFVARADDVI-LSSGYRIGPFEVENALNEHPSVAE 505
+G + R ++ L+ G I P ++EN N V +
Sbjct: 532 NGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQ 570
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,370,579
Number of Sequences: 37866
Number of extensions: 1086753
Number of successful extensions: 3112
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 2677
Number of HSP's gapped (non-prelim): 427
length of query: 586
length of database: 18,247,518
effective HSP length: 108
effective length of query: 478
effective length of database: 14,157,990
effective search space: 6767519220
effective search space used: 6767519220
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.