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Search of human proteins with 42476066
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]
(1049 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens] 2134 0.0
gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens] 2134 0.0
gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens] 2112 0.0
gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor ... 93 1e-18
gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [H... 77 7e-14
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 60 8e-09
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 60 8e-09
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 60 1e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 57 7e-08
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 55 3e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 1e-06
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 54 1e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 54 1e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 54 1e-06
gi|93141033 PAX interacting protein 1 [Homo sapiens] 52 2e-06
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 52 3e-06
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 52 4e-06
gi|209862789 microtubule associated monoxygenase, calponin and L... 52 4e-06
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 51 7e-06
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 51 7e-06
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 51 7e-06
gi|19924099 synapsin I isoform Ia [Homo sapiens] 50 1e-05
gi|50345997 E1A binding protein p300 [Homo sapiens] 50 1e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 50 1e-05
gi|33286444 mastermind-like 2 [Homo sapiens] 50 1e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 50 1e-05
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 49 2e-05
gi|73808090 zinc finger protein 207 isoform b [Homo sapiens] 49 2e-05
gi|50345881 cytoplasmic polyadenylation element binding protein ... 49 3e-05
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 49 3e-05
>gi|42476066 SMG-7 homolog isoform 4 [Homo sapiens]
Length = 1049
Score = 2134 bits (5530), Expect = 0.0
Identities = 1049/1049 (100%), Positives = 1049/1049 (100%)
Query: 1 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 60
MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY
Sbjct: 1 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 60
Query: 61 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 120
TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA
Sbjct: 61 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 120
Query: 121 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 180
RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA
Sbjct: 121 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 180
Query: 181 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 240
STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR
Sbjct: 181 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 240
Query: 241 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 300
LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL
Sbjct: 241 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 300
Query: 301 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 360
CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP
Sbjct: 301 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 360
Query: 361 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 420
HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI
Sbjct: 361 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 420
Query: 421 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 480
GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG
Sbjct: 421 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 480
Query: 481 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE 540
LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE
Sbjct: 481 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE 540
Query: 541 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 600
ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG
Sbjct: 541 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 600
Query: 601 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP 660
VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP
Sbjct: 601 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP 660
Query: 661 AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG 720
AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG
Sbjct: 661 AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG 720
Query: 721 PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE 780
PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE
Sbjct: 721 PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE 780
Query: 781 FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS 840
FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS
Sbjct: 781 FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS 840
Query: 841 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 900
SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP
Sbjct: 841 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 900
Query: 901 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT 960
SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT
Sbjct: 901 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT 960
Query: 961 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM 1020
DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM
Sbjct: 961 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM 1020
Query: 1021 HPGPSALEQLLMQQKQKQQRGQGTMNPPH 1049
HPGPSALEQLLMQQKQKQQRGQGTMNPPH
Sbjct: 1021 HPGPSALEQLLMQQKQKQQRGQGTMNPPH 1049
>gi|42476070 SMG-7 homolog isoform 2 [Homo sapiens]
Length = 1091
Score = 2134 bits (5530), Expect = 0.0
Identities = 1049/1049 (100%), Positives = 1049/1049 (100%)
Query: 1 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 60
MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY
Sbjct: 43 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 102
Query: 61 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 120
TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA
Sbjct: 103 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 162
Query: 121 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 180
RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA
Sbjct: 163 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 222
Query: 181 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 240
STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR
Sbjct: 223 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 282
Query: 241 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 300
LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL
Sbjct: 283 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 342
Query: 301 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 360
CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP
Sbjct: 343 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 402
Query: 361 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 420
HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI
Sbjct: 403 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 462
Query: 421 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 480
GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG
Sbjct: 463 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 522
Query: 481 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE 540
LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE
Sbjct: 523 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSE 582
Query: 541 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 600
ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG
Sbjct: 583 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 642
Query: 601 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP 660
VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP
Sbjct: 643 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLP 702
Query: 661 AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG 720
AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG
Sbjct: 703 AQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQG 762
Query: 721 PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE 780
PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE
Sbjct: 763 PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE 822
Query: 781 FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS 840
FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS
Sbjct: 823 FYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHS 882
Query: 841 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 900
SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP
Sbjct: 883 SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSP 942
Query: 901 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT 960
SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT
Sbjct: 943 SLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKT 1002
Query: 961 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM 1020
DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM
Sbjct: 1003 DKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMM 1062
Query: 1021 HPGPSALEQLLMQQKQKQQRGQGTMNPPH 1049
HPGPSALEQLLMQQKQKQQRGQGTMNPPH
Sbjct: 1063 HPGPSALEQLLMQQKQKQQRGQGTMNPPH 1091
>gi|42475558 SMG-7 homolog isoform 1 [Homo sapiens]
Length = 1137
Score = 2112 bits (5473), Expect = 0.0
Identities = 1049/1095 (95%), Positives = 1049/1095 (95%), Gaps = 46/1095 (4%)
Query: 1 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 60
MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY
Sbjct: 43 MLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFY 102
Query: 61 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 120
TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA
Sbjct: 103 TQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIA 162
Query: 121 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 180
RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA
Sbjct: 163 RYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAA 222
Query: 181 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 240
STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR
Sbjct: 223 STNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKR 282
Query: 241 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 300
LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL
Sbjct: 283 LLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGIL 342
Query: 301 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 360
CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP
Sbjct: 343 CKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHP 402
Query: 361 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 420
HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI
Sbjct: 403 HEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISI 462
Query: 421 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 480
GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG
Sbjct: 463 GKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPG 522
Query: 481 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEV------------- 527
LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEV
Sbjct: 523 LKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKN 582
Query: 528 ---------------------------------KSQTELRKTPVSEARKTPVTQTPTQAS 554
KSQTELRKTPVSEARKTPVTQTPTQAS
Sbjct: 583 DGKKDNNKRKTETKKCTLEKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQAS 642
Query: 555 NSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS 614
NSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS
Sbjct: 643 NSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS 702
Query: 615 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 674
PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ
Sbjct: 703 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 762
Query: 675 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 734
ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL
Sbjct: 763 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 822
Query: 735 QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS 794
QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS
Sbjct: 823 QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS 882
Query: 795 VMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQE 854
VMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQE
Sbjct: 883 VMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQE 942
Query: 855 RYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQ 914
RYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQ
Sbjct: 943 RYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQ 1002
Query: 915 SPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLS 974
SPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLS
Sbjct: 1003 SPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLS 1062
Query: 975 ATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQ 1034
ATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQ
Sbjct: 1063 ATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQ 1122
Query: 1035 KQKQQRGQGTMNPPH 1049
KQKQQRGQGTMNPPH
Sbjct: 1123 KQKQQRGQGTMNPPH 1137
>gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor
[Homo sapiens]
Length = 1419
Score = 92.8 bits (229), Expect = 1e-18
Identities = 58/206 (28%), Positives = 98/206 (47%), Gaps = 15/206 (7%)
Query: 2 LVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYT 61
++ D+E++ ++ V+Q LW +AF I + K+ N +++ L L+ S F+
Sbjct: 627 ILLDIEFSDNQNVDQILWKNAFYQVIEKFRQLVKDPNVENPEQIRNRLLELLDEGSDFFD 686
Query: 62 QLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIAR 121
LLQ+L + L + + ++T A++ Q C++ GDIAR
Sbjct: 687 SLLQKLQVTYKFKLEDYMDGLAIRSKPLRKTVKYALIS---------AQRCMICQGDIAR 737
Query: 122 YRNQTS------QAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKF 175
YR Q S +A S+Y A + P NG+PYNQLA+LA L ++YY RS+A
Sbjct: 738 YREQASDTANYGKARSWYLKAQHIAPKNGRPYNQLALLAVYTRRKLDAVYYYMRSLAASN 797
Query: 176 PFPAASTNLQKALSKALESRDEVKTK 201
P A +L + ++++ K
Sbjct: 798 PILTAKESLMSLFEETKRKAEQMEKK 823
Score = 36.6 bits (83), Expect = 0.13
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 29/147 (19%)
Query: 207 FIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLL--FQKAFNSQQLVHVTVINLFQLH 264
FI +F+ HG ++ +E + EK+ ++F+ LL S +++ + IN+F +H
Sbjct: 892 FILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVH 951
Query: 265 H--LRD-FSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPL-------------QNE 308
+ L+D FS E Q L LA+F S L C C L Q++
Sbjct: 952 NSQLKDCFSEECRSVIQEQAAALG----LAMF-SLLVRRCTCLLKESAKAQLSSPEDQDD 1006
Query: 309 SQEESYNAYP------LPAVKVSMDWL 329
+ +++ LP+VKV DW+
Sbjct: 1007 QDDIKVSSFVPDLKELLPSVKVWSDWM 1033
>gi|187960090 SMG5 homolog nonsense mediated mRNA decay factor [Homo
sapiens]
Length = 1016
Score = 77.4 bits (189), Expect = 7e-14
Identities = 56/203 (27%), Positives = 95/203 (46%), Gaps = 26/203 (12%)
Query: 12 KKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVF 71
+K E+ LW + I ++ K+ + RS ++ L A GFY LL + + +
Sbjct: 76 RKAEELLWRKVYYEVIQLIKTNKKHIHS--RSTLECAYRTHLVAGIGFYQHLLLYIQSHY 133
Query: 72 NVDLPCRVKSSQLGIISNKQTHTSAIV---KPQSSS------CSYICQHCLVHLGDIARY 122
++L C + + + T ++ KP S+S C CLV+LGD++RY
Sbjct: 134 QLELQCCIDWTHV---------TDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGDLSRY 184
Query: 123 RNQTSQ------AESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFP 176
+N+ + AE +Y A + P G P+NQL LA SK ++ ++ Y R I +
Sbjct: 185 QNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYNVEAMYCYLRCIQSEVS 244
Query: 177 FPAASTNLQKALSKALESRDEVK 199
F A NL++ KA + ++K
Sbjct: 245 FEGAYGNLKRLYDKAAKMYHQLK 267
Score = 41.6 bits (96), Expect = 0.004
Identities = 44/168 (26%), Positives = 69/168 (41%), Gaps = 24/168 (14%)
Query: 319 LPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLN-------------SFHPHEEDL 365
LPAVKV +DWLR P + Q +W L LLN + P +DL
Sbjct: 655 LPAVKVFLDWLRTNPDLI-IVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDL 713
Query: 366 SSISATP-------LPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLI 418
P LPE+ L+ LR + R +F ++ +E +R +
Sbjct: 714 LEGCELPDLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESV---VRICCIR 770
Query: 419 SIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQE 466
S G +IA Q ++Q EVG + I + + L ++A+ + +E
Sbjct: 771 SFGHFIARLQGSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEE 818
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 60.5 bits (145), Expect = 8e-09
Identities = 115/475 (24%), Positives = 159/475 (33%), Gaps = 85/475 (17%)
Query: 545 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF-PAGVSV 603
P+ +TP +S P+ G P P G P + PP G GY P G
Sbjct: 373 PLARTPQPSS-----PMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426
Query: 604 PGTF---LQPTAHSPAGNQVQAGKQSHIPYSQQRPSG--------------PGPMNQGPQ 646
P + +Q A S G Q PY QQ PSG P P Q P
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYT--QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484
Query: 647 QS-QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQ 705
S QPPSQ P AQP+ Q Q Q L Q Q P P+ PPH Y
Sbjct: 485 YSQQPPSQTP----HAQPSYQQQPQSQPPQL-QSSQPPYSQQPS---QPPHQQSPAPYPS 536
Query: 706 ADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFP 765
++ Q P QP Y Q P Q P QQQP + P
Sbjct: 537 QQSTTQQ-------------HPQSQPPYSQ---------PQAQSPYQQQQPQQ------P 568
Query: 766 MEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPF 825
+ P+ + + R Q+ + D G ++ P M
Sbjct: 569 APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA--------SSAPSMTS 620
Query: 826 EKSLLEKPS-ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAP 884
K E + L S SS L+G + ++ V ++SS + +P+ +P
Sbjct: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680
Query: 885 ----QETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV--PF 938
L + +P PAS S SP + + +P PP+ +S+ P
Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740
Query: 939 SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTW 993
N I +R + P G SA S + S Q T G++
Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPG-------SALSPRQPSGGQIHTGMGSY 788
Score = 36.2 bits (82), Expect = 0.17
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 19/121 (15%)
Query: 550 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPAGVSVPGTF 607
P Q S+ P H ++ P+R +PPP Y + P + GSG AG P
Sbjct: 198 PQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP--- 252
Query: 608 LQPTAHSPAGNQVQAGKQSHIPYSQQR---PSGPGPMNQGPQQSQPPSQQPLTSLPAQPT 664
P++ + A + S ++QQR G GP G QP + L L P+
Sbjct: 253 --PSSSASASS-------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS 303
Query: 665 A 665
+
Sbjct: 304 S 304
Score = 33.1 bits (74), Expect = 1.4
Identities = 91/420 (21%), Positives = 139/420 (33%), Gaps = 54/420 (12%)
Query: 516 RDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPG 575
+ Q +S PP+ SQ + P + P+Q S +Q HP + PP S+P
Sbjct: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ----QHPQSQPPY-SQPQ 555
Query: 576 FPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRP 635
P P PA P T Q A+ Q Q+ + YSQQR
Sbjct: 556 AQSPYQQQQPQQ----------PA----PSTLSQQAAYP----QPQSQQSQQTAYSQQRF 597
Query: 636 SGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL--GKS 693
P ++Q SQ S +TS Q L +Q+ + ++ L G
Sbjct: 598 PPPQELSQDSFGSQASSAPSMTS---SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE 654
Query: 694 PPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS-LQPPVM 752
G + + + NP Q P P+ + P PS + P
Sbjct: 655 GALSPGVSTSGISSSQGEQSNPAQ-----SPFSPHTSPHLPGIRGP----SPSPVGSPAS 705
Query: 753 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 812
Q + P + P N P + P DS + N+S +AQ +R + P
Sbjct: 706 VAQSRSGPLSPAAV-PGNQMPP--RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762
Query: 813 FRPEQDPV--PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLN-QERYPNNSMFNEVYGKN 869
P+ PR P + +S G Q YP +N + N
Sbjct: 763 SSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNAN 822
Query: 870 LTSSSKA-ELSPSMAPQETSLYSLFEGTPWSP---SLPASSDHSTPASQSPHSSNPSSLP 925
S+ A ++P A + G P P +LP P+ N +++P
Sbjct: 823 YPSAGMAGGINPMGAGGQ------MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMP 876
Score = 31.6 bits (70), Expect = 4.1
Identities = 37/186 (19%), Positives = 64/186 (34%), Gaps = 21/186 (11%)
Query: 600 GVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSL 659
G + P T T PAG G Q+ P+ R P QQ+ PP
Sbjct: 1432 GNAYPATATAATERRPAG-----GPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQ 1486
Query: 660 PAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQL-----W- 713
+ AQ + Q + + ++ + + P +H + + ++ W
Sbjct: 1487 ASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWP 1546
Query: 714 -----NPPQVQGPLGKIMPVKQPYYLQTQDPIKLFE--PSLQPPVMQQQPLEKKMKPFPM 766
PP GP + P+ +P Q P + P + P +P+E + P
Sbjct: 1547 SHGTRQPP--YGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSP-SK 1603
Query: 767 EPYNHN 772
P+ H+
Sbjct: 1604 SPFLHS 1609
Score = 31.2 bits (69), Expect = 5.3
Identities = 48/226 (21%), Positives = 79/226 (34%), Gaps = 20/226 (8%)
Query: 629 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 688
PYS+ G G + GP+Q P P + +P + A Q P+
Sbjct: 1259 PYSRAAGPGLGNVAMGPRQHYPYG-GPYDRVRTEPGIGPEGNMSTGA-PQPNLMPSNPDS 1316
Query: 689 ALGKSPPHHSGFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQP--YYLQTQDPIKLFEP 745
+ SP + QQ QQ N QG P G P +Q Y Q Q+ + +
Sbjct: 1317 GM-YSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDG 1375
Query: 746 SLQPPVM--------------QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMAD 791
+ PP Q QP ++++ P +P + + P+ + Y A
Sbjct: 1376 TYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAY 1435
Query: 792 NRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELM 837
+ A G ++ F+ +D V P + P ++M
Sbjct: 1436 PATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMM 1481
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 60.5 bits (145), Expect = 8e-09
Identities = 115/475 (24%), Positives = 159/475 (33%), Gaps = 85/475 (17%)
Query: 545 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTF-PAGVSV 603
P+ +TP +S P+ G P P G P + PP G GY P G
Sbjct: 373 PLARTPQPSS-----PMDQMGKMRPQPYG-GTNPYSQQQGPPSGPQQGHGYPGQPYGSQT 426
Query: 604 PGTF---LQPTAHSPAGNQVQAGKQSHIPYSQQRPSG--------------PGPMNQGPQ 646
P + +Q A S G Q PY QQ PSG P P Q P
Sbjct: 427 PQRYPMTMQGRAQSAMGGLSYT--QQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484
Query: 647 QS-QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQ 705
S QPPSQ P AQP+ Q Q Q L Q Q P P+ PPH Y
Sbjct: 485 YSQQPPSQTP----HAQPSYQQQPQSQPPQL-QSSQPPYSQQPS---QPPHQQSPAPYPS 536
Query: 706 ADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFP 765
++ Q P QP Y Q P Q P QQQP + P
Sbjct: 537 QQSTTQQ-------------HPQSQPPYSQ---------PQAQSPYQQQQPQQ------P 568
Query: 766 MEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPF 825
+ P+ + + R Q+ + D G ++ P M
Sbjct: 569 APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQA--------SSAPSMTS 620
Query: 826 EKSLLEKPS-ELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAP 884
K E + L S SS L+G + ++ V ++SS + +P+ +P
Sbjct: 621 SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680
Query: 885 ----QETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV--PF 938
L + +P PAS S SP + + +P PP+ +S+ P
Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740
Query: 939 SNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTW 993
N I +R + P G SA S + S Q T G++
Sbjct: 741 MNQSSIAQDRGYMQRNPQMPQYSSPQPG-------SALSPRQPSGGQIHTGMGSY 788
Score = 36.2 bits (82), Expect = 0.17
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 19/121 (15%)
Query: 550 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPAGVSVPGTF 607
P Q S+ P H ++ P+R +PPP Y + P + GSG AG P
Sbjct: 198 PQQNSHDHGFPNHQYNSY--YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPP--- 252
Query: 608 LQPTAHSPAGNQVQAGKQSHIPYSQQR---PSGPGPMNQGPQQSQPPSQQPLTSLPAQPT 664
P++ + A + S ++QQR G GP G QP + L L P+
Sbjct: 253 --PSSSASASS-------SSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPS 303
Query: 665 A 665
+
Sbjct: 304 S 304
Score = 33.1 bits (74), Expect = 1.4
Identities = 91/420 (21%), Positives = 139/420 (33%), Gaps = 54/420 (12%)
Query: 516 RDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPG 575
+ Q +S PP+ SQ + P + P+Q S +Q HP + PP S+P
Sbjct: 501 QQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQ----QHPQSQPPY-SQPQ 555
Query: 576 FPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRP 635
P P PA P T Q A+ Q Q+ + YSQQR
Sbjct: 556 AQSPYQQQQPQQ----------PA----PSTLSQQAAYP----QPQSQQSQQTAYSQQRF 597
Query: 636 SGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPAL--GKS 693
P ++Q SQ S +TS Q L +Q+ + ++ L G
Sbjct: 598 PPPQELSQDSFGSQASSAPSMTS---SKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTE 654
Query: 694 PPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS-LQPPVM 752
G + + + NP Q P P+ + P PS + P
Sbjct: 655 GALSPGVSTSGISSSQGEQSNPAQ-----SPFSPHTSPHLPGIRGP----SPSPVGSPAS 705
Query: 753 QQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGV 812
Q + P + P N P + P DS + N+S +AQ +R + P
Sbjct: 706 VAQSRSGPLSPAAV-PGNQMPP--RPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQY 762
Query: 813 FRPEQDPV--PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLN-QERYPNNSMFNEVYGKN 869
P+ PR P + +S G Q YP +N + N
Sbjct: 763 SSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNAN 822
Query: 870 LTSSSKA-ELSPSMAPQETSLYSLFEGTPWSP---SLPASSDHSTPASQSPHSSNPSSLP 925
S+ A ++P A + G P P +LP P+ N +++P
Sbjct: 823 YPSAGMAGGINPMGAGGQ------MHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMP 876
Score = 33.1 bits (74), Expect = 1.4
Identities = 46/199 (23%), Positives = 73/199 (36%), Gaps = 16/199 (8%)
Query: 629 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 688
PYS+ G G + GP+Q P P + +P + A Q P+
Sbjct: 1259 PYSRAAGPGLGNVAMGPRQHYPYG-GPYDRVRTEPGIGPEGNMSTGA-PQPNLMPSNPDS 1316
Query: 689 ALGKSPPHHSGFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQPYYLQTQDPIKLFEPSL 747
+ SP + QQ QQ N QG P G P +Q Q Q + P
Sbjct: 1317 GM-YSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQVSSPAPLP 1375
Query: 748 QPPVMQQQPLE--------KKMKPFPMEPYNH-NPSEVKVPEFYWDSSY---SMADNRSV 795
+P + P + K K P P +H P+ V+ P D ++ S+ + V
Sbjct: 1376 RPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPV 1435
Query: 796 MAQQANIDRRGKRSPGVFR 814
+ Q+ + + +P +R
Sbjct: 1436 LKQRRRLTMKDIGTPEAWR 1454
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 60.1 bits (144), Expect = 1e-08
Identities = 93/385 (24%), Positives = 144/385 (37%), Gaps = 58/385 (15%)
Query: 584 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 643
PPP M + P T LQ A Q Q +Q + QQ+ + Q
Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQTQLQ--LQQVALQQQQQQQQ----FQQQQQAALQQQQQ 182
Query: 644 GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQY 703
QQ Q +QQ Q Q QLQ Q QQQQ K HH QQ
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ--QQQQQHLIKL---------HHQNQQQI 231
Query: 704 QQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 763
QQ +QL Q+Q L + +Q Q Q ++ P QPP+ Q QP + P
Sbjct: 232 QQ--QQQQLQRIAQLQ--LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287
Query: 764 FPMEPYNHNPSEVKVPEFYWDSSYSMADNR----SVMAQQANIDRRGKRSPGVFRPEQDP 819
++ +H P+ +A N+ +Q + + + PG Q P
Sbjct: 288 QQLQQMHHTQHHQPPPQ---PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344
Query: 820 ---------VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNL 870
V + P + + ++ + + + ++ + G ++Q P + + G+ +
Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLP--MLSSPSPGQQV 402
Query: 871 TSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHS--SNPSSLPSSP 928
+ P +PQ P PS +S+ S+ + SP S +PS PS
Sbjct: 403 QTPQSMPPPPQPSPQ-----------PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 451
Query: 929 P----THNHNSVPFSNFGPIGTPDN 949
P T + SVP + GP+ TP N
Sbjct: 452 PVTARTPQNFSVP--SPGPLNTPVN 474
Score = 37.7 bits (86), Expect = 0.057
Identities = 62/268 (23%), Positives = 97/268 (36%), Gaps = 39/268 (14%)
Query: 509 IKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFP 568
++ ++ + Q + + +++Q +++ P+ + + P P Q H P P
Sbjct: 246 LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQP 305
Query: 569 PLP----SRPGFPPPTYVIPPPVAFSMGSG----YTFP--AGVSVPGTFLQPTAH----- 613
P ++P PP P V+ + YT P V P QP
Sbjct: 306 QQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Query: 614 -------SPAGNQVQAG---KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQP 663
+ A V G QS +P PS PG Q P QS PP QP + P QP
Sbjct: 366 QQTAVQTAQAAQMVAPGVQVSQSSLPMLSS-PS-PGQQVQTP-QSMPPPPQP-SPQPGQP 421
Query: 664 TAQSTSQLQVQALTQQQQSPTKAVPALGKSP---PHHSGFQQYQQADASKQL---WNPPQ 717
++Q S + + SP+ +P+ P P + Q + L NP
Sbjct: 422 SSQPNSNVS----SGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSS 477
Query: 718 VQGPLGKIMPVKQPYYLQTQDPIKLFEP 745
V P G +Q Y + + K EP
Sbjct: 478 VMSPAGSSQAEEQQYLDKLKQLSKYIEP 505
Score = 33.5 bits (75), Expect = 1.1
Identities = 48/225 (21%), Positives = 80/225 (35%), Gaps = 14/225 (6%)
Query: 523 PPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYV 582
PP V+ Q + ++T V A+ + Q S S + P + + PPP
Sbjct: 357 PP--VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP 414
Query: 583 IPPPVAFSMGSGYTFPAG-VSVPGTFLQPTAHSPAGNQVQAGKQSHI----PYSQQRPSG 637
P P S +G P +FL + P+ + V A + P P
Sbjct: 415 SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVN 474
Query: 638 PGPMNQGPQQSQPPSQQPLTSLP-----AQPTAQSTSQLQVQALTQQQQSPTKAVPALGK 692
P + SQ QQ L L +P + +++ ++ S K++ +
Sbjct: 475 PSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILT 534
Query: 693 SPPHHSGFQQYQQAD-ASKQLWNPPQV-QGPLGKIMPVKQPYYLQ 735
P + Q+ + A ++L N V P + P KQ Y Q
Sbjct: 535 DPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQ 579
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 57.4 bits (137), Expect = 7e-08
Identities = 147/619 (23%), Positives = 220/619 (35%), Gaps = 122/619 (19%)
Query: 391 NLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPEL 450
+LD +K + G+K G+ I Q R S+ ++ P I+ + E K + E+
Sbjct: 619 SLDINK----LPGEKLGRVVHIIQSREPSL----KNSNPDEIEIDFETLKPSTLRELERY 670
Query: 451 ILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIK 510
+ + ++ + ++ +A GS +K S+ S+ + + E+ +
Sbjct: 671 VTSCLRKKRK----PQAEKVDVIA--GSSKMKGFSSSESESSSESSSSDS------EDSE 718
Query: 511 TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL 570
T + + + P +E K + +A PV Q P PP
Sbjct: 719 TEMAPKSKKKGHPGREQKKHHHHHHQQMQQA-PAPVPQQP-----------------PPP 760
Query: 571 PSRPGFPPP----TYVIPPPVAFSMGSGYTFPAGVSVPGTF-------LQP----TAHSP 615
P +P PPP PPP SM PA S P F L+P + P
Sbjct: 761 PQQPPPPPPPQQQQQPPPPPPPPSMPQ-QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDP 819
Query: 616 AGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPP--SQQPLTSLP----AQPTAQSTS 669
G+ Q H+P +P P + Q P+ S PP +Q + S P A P S
Sbjct: 820 IGHFTQ--PILHLP----QPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRP 873
Query: 670 QLQVQALTQQQQSPTKAVPALGKSP--PHHSGFQQYQQADASKQLWNPP----QVQGPLG 723
+ AL + P PAL ++P P Q Q ++ PP Q+Q L
Sbjct: 874 SNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQ 933
Query: 724 KIMPVKQPYYL------QTQDPIKL---FEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPS 774
++ V+ P L Q+Q P L PS+Q + QQ P +P P H P
Sbjct: 934 QLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPP 993
Query: 775 EVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEK------- 827
V S + QQ G++ P P Q P+ +
Sbjct: 994 PRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPP----PPQPAKPQQVIQHHHSPRHH 1049
Query: 828 --------SLLEKPSELMSHS---SSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKA 876
L E PS LM HS S F SLT S Q+ + L ++S
Sbjct: 1050 KSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKK-------QELRAASVV 1102
Query: 877 ELSPSMAPQETSLYS-LFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP---PTHN 932
+ P + +E ++S + P+SPSL P P LP P P
Sbjct: 1103 QPQPLVVVKEEKIHSPIIRSEPFSPSL-----RPEPPKHPESIKAPVHLPQRPEMKPVDV 1157
Query: 933 HNSV---PFSNFGPIGTPD 948
V P N P G PD
Sbjct: 1158 GRPVIRPPEQNAPPPGAPD 1176
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 [Homo
sapiens]
Length = 2191
Score = 55.1 bits (131), Expect = 3e-07
Identities = 130/536 (24%), Positives = 191/536 (35%), Gaps = 88/536 (16%)
Query: 565 GAFPPLPSRPGFPPPTYVIPPPVAFSMGS---GYTFPAGVSVPGTF-LQPTAHSPAGNQV 620
G++P S P PPP P A + G+ G AG+ + Q A SPA
Sbjct: 377 GSYPEYSS-PSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAA 435
Query: 621 QAGKQSHIPYSQQRPSGPGPM---NQGPQQSQPPSQQP-LTSLPAQPTAQSTSQLQVQAL 676
Q ++SH S P PGP +QG ++P L + + P +Q
Sbjct: 436 Q--QRSHPAMS---PGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGG 490
Query: 677 TQQQQSPTK-AVPALGKSPPHHSGFQQYQQADASKQLWN------PPQV--QGPLGKIMP 727
+ P + + G++P +G Q QQ D+ W PPQ QG G
Sbjct: 491 SYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQ 550
Query: 728 VKQPYYLQTQDPIKL-----FEPS-----LQPPV-MQQQPLEKKMKPFPMEPYNHNPSEV 776
+QPYY Q P L + PS QP M Q+ + +P P+ P N ++
Sbjct: 551 GQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQP-PLAPGKPNHEDL 609
Query: 777 KV-----PEFYWDSSYSMAD---------NRSVMAQQANIDRRGKRSP--GVFRPEQDP- 819
+ P D S S+ D + +V A + + + +P F P P
Sbjct: 610 NLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPH 669
Query: 820 ---VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKA 876
+P P PS + S S S +G ++ P + M + G SSS
Sbjct: 670 LSSIPGGP-------SPSPVGSPVGSNQSRSG-PISPASIPGSQMPPQPPGSQSESSSHP 721
Query: 877 ELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSV 936
LS S PQE + GT +P + T S SPH S P + + S
Sbjct: 722 ALSQSPMPQERGFMA---GTQRNPQMAQYGPQQTGPSMSPHPS-PGGQMHAGISSFQQSN 777
Query: 937 PFSNFGP----IGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGT 992
+GP G N R PA G + + S S + +
Sbjct: 778 SSGTYGPQMSQYGPQGNYSR---------PPAYSG-----VPSASYSGPGPGMGISANNQ 823
Query: 993 WTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPP 1048
G GPS + AV + + S + P P + + Q+G M PP
Sbjct: 824 MHGQGPS-QPCGAVPLGRMPS--AGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPP 876
Score = 44.7 bits (104), Expect = 5e-04
Identities = 80/319 (25%), Positives = 115/319 (36%), Gaps = 37/319 (11%)
Query: 397 GHQGITGD-KEGQQRRIRQQ----RLISIGKWIADNQPRLIQCENEVGKLLFITEI-PEL 450
G QG++G ++GQQ QQ L +++ + Q + ++ + + T P L
Sbjct: 540 GQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPL 599
Query: 451 ILEDPSEAKENLILQE--------TSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPV 502
P+ NLI QE + I+ L L S +S S + S+ D
Sbjct: 600 APGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQ 659
Query: 503 VTFKENIKTREVNRDQGRSFPPKEVKS---QTELRKTPVSEARKTPVTQTPTQASNSQFI 559
F + + G S P V S + R P+S A P +Q P Q SQ
Sbjct: 660 SPFSPHASPHLSSIPGGPS--PSPVGSPVGSNQSRSGPISPA-SIPGSQMPPQPPGSQSE 716
Query: 560 PIHHPG-AFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGN 618
HP + P+P GF T P + G G + P H G
Sbjct: 717 SSSHPALSQSPMPQERGFMAGTQRNPQMAQY----------GPQQTGPSMSP--HPSPGG 764
Query: 619 QVQAGKQSHIPYSQQRPSGPGPMNQGPQ--QSQPPSQQPLTSLP-AQPTAQSTSQLQVQA 675
Q+ AG S + GP GPQ S+PP+ + S + P Q
Sbjct: 765 QMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQM 824
Query: 676 LTQQQQSPTKAVPALGKSP 694
Q P AVP LG+ P
Sbjct: 825 HGQGPSQPCGAVP-LGRMP 842
Score = 33.1 bits (74), Expect = 1.4
Identities = 52/225 (23%), Positives = 72/225 (32%), Gaps = 39/225 (17%)
Query: 562 HHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ 621
H PG +P P+ Y PP G Y + Q ++
Sbjct: 1303 HQPGLYPQQPNYKRHMDGMY--GPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRP 1360
Query: 622 AGKQSHIPYSQQRPSGPGPMNQ---GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 678
Q PYS++R GPG + PQ P Q + P Q + + + +
Sbjct: 1361 IQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNR 1420
Query: 679 Q-QQSPTKAVPALGKS------------------PPHHSGFQQYQQADASKQ-LWNPPQV 718
Q PT+A P G + P H S Q Y + AS Q + PP
Sbjct: 1421 QGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPP-- 1478
Query: 719 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 763
QP Y QT + P Q+ LE +M P
Sbjct: 1479 -----------QPSY-QTPPSLPNHISRAPSPASFQRSLENRMSP 1511
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 53.5 bits (127), Expect = 1e-06
Identities = 119/459 (25%), Positives = 169/459 (36%), Gaps = 86/459 (18%)
Query: 529 SQTELRKTPVSEARKTPVTQT-PTQASNSQFIPIHHPGAFPP-----LPSRPGFPP---- 578
S T+ R P + TP+ T P + +P+ P P LPS P PP
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 579 PTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSP----AGNQVQAGKQSHIPYSQQR 634
P+ PP A S T P + VP + P+ +P A + +QA P Q
Sbjct: 370 PSMTTPPMQA--PPSLQTIPP-IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
Query: 635 PSGPGPMNQGPQQSQ----------------PPSQQPLTSLPAQPTAQSTSQLQVQALTQ 678
S + P+Q+Q PP Q PL SLPA P Q++ V L+
Sbjct: 427 HSF---LTMSPRQTQASLTSPSRPASTPPDSPPLQAPL-SLPASPPLQTSLSPAVSPLSS 482
Query: 679 QQQ-SPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQ 737
P +A+ +L P QA S + P + Q L P L T
Sbjct: 483 PLTIHPLQALSSLASHSP---------QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 738 DPIKLFEPSLQPPVMQQQP-------LEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMA 790
L PSL PP +Q LE P P P PS + P SS +
Sbjct: 534 PLENL--PSLAPPPLQTASAPLTTPHLETPPCPAPC-PLQAPPSPLTTPPPETPSSIATP 590
Query: 791 DNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFS 850
++ A A+ +G SP + P P P+ P +L P + + L+ +
Sbjct: 591 PPQAPPAL-ASPPLQGLPSPPL-SPLATPPPQAPPXLAL--PPLQAPPSPPASPPLSPLA 646
Query: 851 LNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHST 910
+ PN + + +A SP +P + +S P+ P S +T
Sbjct: 647 TPSPQAPNALAVHLL---------QAPFSPPPSPPVQAPFS-------PPASPPVSPSAT 690
Query: 911 PASQSPHS--SNPSSLPSSPPTHNHNSVPFSNFGPIGTP 947
P SQ+P S + P +P SPP S P S P TP
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPA----SPPMS---PSATP 722
Score = 43.1 bits (100), Expect = 0.001
Identities = 83/378 (21%), Positives = 127/378 (33%), Gaps = 61/378 (16%)
Query: 586 PVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGP 645
P ++ +G PGT A + G P ++ RP GP
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210
Query: 646 QQSQPPSQQPLTSLPAQPTA----QSTSQLQVQALTQQQQSPTKAVPALGKSP--PHHSG 699
S+ + +P + +P+A Q + + + SP ++ P+ +P P H
Sbjct: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270
Query: 700 FQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYY---LQTQDPIKLFEPSLQPPVMQQQP 756
Q Q PPQV P P P L T P + PP P
Sbjct: 271 ----QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP 326
Query: 757 LEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPE 816
L + P P P +P + + A + SP P
Sbjct: 327 LPATLPPSP-------PLATPLP-------------LAPPSPSAPPSLQTLPSPPATPPS 366
Query: 817 QDP----VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTS 872
Q P P M SL P + HS + SL + P+ + +
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL-------QAPPSPLALSSLQATTSLG 419
Query: 873 SSKAELSPS---MAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPP 929
S + + S M+P++T + + SPS PAS+ +P Q+ P SLP+SPP
Sbjct: 420 SPTLQATHSFLTMSPRQT------QASLTSPSRPASTPPDSPPLQA-----PLSLPASPP 468
Query: 930 THNHNSVPFSNFGPIGTP 947
S S P+ +P
Sbjct: 469 LQTSLSPAVS---PLSSP 483
Score = 35.4 bits (80), Expect = 0.28
Identities = 65/245 (26%), Positives = 86/245 (35%), Gaps = 39/245 (15%)
Query: 535 KTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPP------PVA 588
+TP S A TP Q P ++ + P PL + P PP +PP P A
Sbjct: 582 ETPSSIA--TPPPQAPPALASPPLQGLPSP-PLSPLATPPPQAPPXLALPPLQAPPSPPA 638
Query: 589 FSMGSGYTFP---AGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQR-----PSGPGP 640
S P A ++ LQ P VQA P+S PS P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA------PFSPPASPPVSPSATPP 692
Query: 641 MNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGF 700
P + PP Q P S PA P ++ QA P + P+ SPP
Sbjct: 693 SQAPPSLAAPPLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP----- 746
Query: 701 QQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIK-LFEPSLQ-PPVMQQQPLE 758
S PP+V PL P++ P P+ L +P Q PP + PL+
Sbjct: 747 -------MSPSATPPPRVP-PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798
Query: 759 KKMKP 763
P
Sbjct: 799 ALPSP 803
Score = 35.4 bits (80), Expect = 0.28
Identities = 36/142 (25%), Positives = 47/142 (33%), Gaps = 11/142 (7%)
Query: 537 PVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFP--------PPTYVIPPPVA 588
P+S + P P A+ +P P + P PS P PP V P P A
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
Query: 589 FSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQS 648
S P + P P P+ A P+S P+ P Q+
Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSP---PASFPGQAPFSPSASLPMSPLATPPPQA 831
Query: 649 QPPSQQPLTSLPAQPTAQSTSQ 670
P PL +P P A T Q
Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQ 853
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 53.5 bits (127), Expect = 1e-06
Identities = 102/436 (23%), Positives = 138/436 (31%), Gaps = 106/436 (24%)
Query: 515 NRDQGRSFP-PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 573
NR S P P++ +S ++ + P Q PT + + P P P LP+
Sbjct: 154 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA---PSSAPPGTPQLPT- 209
Query: 574 PGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQ 633
PG P +PP GS P P PTA P +Q H Q
Sbjct: 210 PGPTPSATAVPP-----QGS----PTASQAPNQPQAPTAPVPH-THIQQAPALH----PQ 255
Query: 634 RPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKS 693
RP P P P S P QPLT QP+A S +Q P G+
Sbjct: 256 RPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQ----------------PPLHGQG 296
Query: 694 PPHHSGFQQ---YQQADASKQLWNPPQV---QGPLGKIMPVKQPYYLQTQDPIKLFEPSL 747
PP Q Q + PPQ Q PLG P+ T + + +L
Sbjct: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH---TSLQLPASQSAL 353
Query: 748 QPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGK 807
Q QQ P E+ + P P+
Sbjct: 354 QS---QQPPREQPLPPAPLA---------------------------------------- 370
Query: 808 RSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYG 867
P + P P+P++P ++ H + FS+N P ++
Sbjct: 371 -MPHIKPPPTTPIPQLPAPQA--------HKHPPHLSGPSPFSMNANLPPPPAL------ 415
Query: 868 KNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSS 927
K L+S S PS P L + P SP+ P S P S P+ L
Sbjct: 416 KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474
Query: 928 PPTHNHNSVPFSNFGP 943
P PF GP
Sbjct: 475 APQPPFAQHPFVPGGP 490
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 53.5 bits (127), Expect = 1e-06
Identities = 102/436 (23%), Positives = 138/436 (31%), Gaps = 106/436 (24%)
Query: 515 NRDQGRSFP-PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 573
NR S P P++ +S ++ + P Q PT + + P P P LP+
Sbjct: 708 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA---PSSAPPGTPQLPT- 763
Query: 574 PGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQ 633
PG P +PP GS P P PTA P +Q H Q
Sbjct: 764 PGPTPSATAVPP-----QGS----PTASQAPNQPQAPTAPVPH-THIQQAPALH----PQ 809
Query: 634 RPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKS 693
RP P P P S P QPLT QP+A S +Q P G+
Sbjct: 810 RPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQ----------------PPLHGQG 850
Query: 694 PPHHSGFQQ---YQQADASKQLWNPPQV---QGPLGKIMPVKQPYYLQTQDPIKLFEPSL 747
PP Q Q + PPQ Q PLG P+ T + + +L
Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH---TSLQLPASQSAL 907
Query: 748 QPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGK 807
Q QQ P E+ + P P+
Sbjct: 908 QS---QQPPREQPLPPAPLA---------------------------------------- 924
Query: 808 RSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYG 867
P + P P+P++P ++ H + FS+N P ++
Sbjct: 925 -MPHIKPPPTTPIPQLPAPQA--------HKHPPHLSGPSPFSMNANLPPPPAL------ 969
Query: 868 KNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSS 927
K L+S S PS P L + P SP+ P S P S P+ L
Sbjct: 970 KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028
Query: 928 PPTHNHNSVPFSNFGP 943
P PF GP
Sbjct: 1029 APQPPFAQHPFVPGGP 1044
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 53.5 bits (127), Expect = 1e-06
Identities = 102/436 (23%), Positives = 138/436 (31%), Gaps = 106/436 (24%)
Query: 515 NRDQGRSFP-PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 573
NR S P P++ +S ++ + P Q PT + + P P P LP+
Sbjct: 708 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA---PSSAPPGTPQLPT- 763
Query: 574 PGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQ 633
PG P +PP GS P P PTA P +Q H Q
Sbjct: 764 PGPTPSATAVPP-----QGS----PTASQAPNQPQAPTAPVPH-THIQQAPALH----PQ 809
Query: 634 RPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKS 693
RP P P P S P QPLT QP+A S +Q P G+
Sbjct: 810 RPPSPHPP---PHPSPHPPLQPLTGSAGQPSAPSHAQ----------------PPLHGQG 850
Query: 694 PPHHSGFQQ---YQQADASKQLWNPPQV---QGPLGKIMPVKQPYYLQTQDPIKLFEPSL 747
PP Q Q + PPQ Q PLG P+ T + + +L
Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH---TSLQLPASQSAL 907
Query: 748 QPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGK 807
Q QQ P E+ + P P+
Sbjct: 908 QS---QQPPREQPLPPAPLA---------------------------------------- 924
Query: 808 RSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYG 867
P + P P+P++P ++ H + FS+N P ++
Sbjct: 925 -MPHIKPPPTTPIPQLPAPQA--------HKHPPHLSGPSPFSMNANLPPPPAL------ 969
Query: 868 KNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSS 927
K L+S S PS P L + P SP+ P S P S P+ L
Sbjct: 970 KPLSSLSTHH-PPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028
Query: 928 PPTHNHNSVPFSNFGP 943
P PF GP
Sbjct: 1029 APQPPFAQHPFVPGGP 1044
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 52.4 bits (124), Expect = 2e-06
Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 14/188 (7%)
Query: 615 PAGNQVQAGKQSHI-PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQV 673
P Q Q +Q+H +SQQ+ P PQQ P QQ Q QLQ
Sbjct: 447 PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQ 506
Query: 674 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYY 733
L QQQ L + HS QQ QQ +Q Q ++ P+
Sbjct: 507 HQLQQQQ---------LAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHL 557
Query: 734 LQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPE--FYWDSSYSMAD 791
QT ++ P QPP QQQ + P + + H+P+ V++PE F +++AD
Sbjct: 558 SQTSQALQHQVPPQQPP-QQQQQQQPPPSPQQHQLFGHDPA-VEIPEEGFLLGCVFAIAD 615
Query: 792 NRSVMAQQ 799
M+ +
Sbjct: 616 YPEQMSDK 623
Score = 44.7 bits (104), Expect = 5e-04
Identities = 46/154 (29%), Positives = 65/154 (42%), Gaps = 24/154 (15%)
Query: 611 TAHSPAGN---QVQAGKQSH-----IPYSQQRPSGPGPMNQGPQQSQPPSQQ-PLTSLPA 661
T +P N QV +Q H + +SQ + + M Q QQ+Q QQ P+ L
Sbjct: 362 TLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQP 421
Query: 662 QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGP 721
Q Q+ L QQQQ P + PPH QQ QQ A ++ Q+Q P
Sbjct: 422 Q---------QIMQLQQQQQQQISQQP-YPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFP 471
Query: 722 LGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ 755
++ P +Q + Q Q +P Q +QQQ
Sbjct: 472 QQQLHPPQQLHRPQQQ-----LQPFQQQHALQQQ 500
Score = 32.7 bits (73), Expect = 1.8
Identities = 50/291 (17%), Positives = 91/291 (31%), Gaps = 27/291 (9%)
Query: 647 QSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPT------KAVPALGKSPPHHSGF 700
QS S+ T PA T ++ + A QQ P+ + + A K+
Sbjct: 320 QSSERSEMIATWSPAVRTLRNITN---NADIQQMNRPSNVAHILQTLSAPTKNLEQQVNH 376
Query: 701 QQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKK 760
Q +A+ L++ +V + +Q Q Q P+ +P + QQQ +
Sbjct: 377 SQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQIS 436
Query: 761 MKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPV 820
+P+P +P + P A QQ ++ P Q +
Sbjct: 437 QQPYPQQPPH--------PFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQL 488
Query: 821 PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSP 880
+ +L ++ +L H L Q++ + + + + +
Sbjct: 489 QPFQQQHALQQQFHQLQQH----------QLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQ 538
Query: 881 SMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTH 931
M Q+ + P + H P Q P P SP H
Sbjct: 539 RMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQH 589
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 52.0 bits (123), Expect = 3e-06
Identities = 59/217 (27%), Positives = 72/217 (33%), Gaps = 32/217 (14%)
Query: 569 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ-----AG 623
P+ P PPP ++ PPP + G P G P Q +P G+ V G
Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQG---PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468
Query: 624 KQSHIPYSQQRPSGPGPMNQGPQQSQ---PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQ 680
P P P P Q P PP QQ P P S+ QQ
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
Query: 681 QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPI 740
+ T G PP +QQ Q A A+ PQ+QG P P Q P+
Sbjct: 529 TTTTTTSAGTGSIPP----WQQQQAAAAASP--GAPQMQG-----NPTMVPLPPGVQPPL 577
Query: 741 KLFEPSLQPPVMQQQPLEKKM-------KPFPMEPYN 770
P PP P M P PM+P N
Sbjct: 578 ---PPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSN 611
Score = 33.9 bits (76), Expect = 0.83
Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 6/49 (12%)
Query: 550 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFP 598
P N +P+ PG PPLP PG PPP PPP S G Y P
Sbjct: 558 PQMQGNPTMVPLP-PGVQPPLP--PGAPPPP---PPPPPGSAGMMYAPP 600
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 51.6 bits (122), Expect = 4e-06
Identities = 108/471 (22%), Positives = 151/471 (32%), Gaps = 87/471 (18%)
Query: 549 TPTQASN-SQFIPIHHPGAFPPLPSRPGFPPPT--YVIPPPVAFSMGSGYTFPA-GVSVP 604
+P+ AS+ S F P + P A+ P P PG P P+ Y+ P A S T PA P
Sbjct: 1547 SPSAASDASGFSPGYSP-AWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSP 1605
Query: 605 GTFL-QPTAHSPAGNQVQAGKQSHIPYS-QQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQ 662
G + Q ++SP S+ P S P+ P P S TS
Sbjct: 1606 GGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1665
Query: 663 PTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPL 722
PT+ S S T SPT SP + Y S +P P
Sbjct: 1666 PTSPSYSP------TSPSYSPT--------SPSYSPTSPSYSPTSPSYSPTSPS--YSPT 1709
Query: 723 GKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFY 782
P Y T PS P P P N+ P+
Sbjct: 1710 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSP---TSPNYTPT-------- 1758
Query: 783 WDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSS 842
SYS SP + P P PS + S
Sbjct: 1759 -SPSYS------------------PTSPSYSPTSPNYTPTSPNYSP--TSPSYSPTSPSY 1797
Query: 843 FLSLTGFSLNQERY-PNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPS 901
+ +S + RY P + + +S S + SPS +P TP SPS
Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTP------SSPSYSPSSPSYSPTSPKY------TPTSPS 1845
Query: 902 LPASSDHSTPASQSPHSSNPSSLPSSP-------------PTHNHNSVPFSNFGPIGTPD 948
SS TP S ++P P+SP P ++ S +S P+ TP
Sbjct: 1846 YSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTP- 1904
Query: 949 NRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPS 999
T+ ++ P Y + + + + ST S T G+ P+
Sbjct: 1905 -----TSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPT 1950
Score = 46.2 bits (108), Expect = 2e-04
Identities = 110/536 (20%), Positives = 167/536 (31%), Gaps = 48/536 (8%)
Query: 484 VLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARK 543
+++ +R+ N DTG +F+E + G S P K V L + +
Sbjct: 1411 LMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGC 1470
Query: 544 TPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGF---PPPTYVIPPPVA-FSMGSGYTFPA 599
+ + IP + PG P+ F P P I P + ++ G+ + A
Sbjct: 1471 FDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGA 1530
Query: 600 GVSVPGTFLQPTA--HSPAGNQVQAG-KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPL 656
G+ + P A SP+ +G + P P PG + GP PS
Sbjct: 1531 WSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPG--SPGPSSPYIPSPGGA 1588
Query: 657 TSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQ-QYQQADASKQLWNP 715
S PT+ + T Q S + P+ + P +S Y S +P
Sbjct: 1589 MSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSP 1648
Query: 716 PQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSE 775
P P Y T PS P P P +PS
Sbjct: 1649 SY--SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1706
Query: 776 VKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSE 835
Y +S S + + + S P P P+
Sbjct: 1707 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPT-----------SPNY 1755
Query: 836 LMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEG 895
+ S + +S Y TS + + SPS +P S
Sbjct: 1756 TPTSPSYSPTSPSYSPTSPNYTP------------TSPNYSPTSPSYSPTSPSY------ 1797
Query: 896 TPWSPSLPASSDHSTPASQSPHSSNPSSLPSSP------PTHNHNSVPFSNFGPIGTPDN 949
+P SPS SS TP S + S+PS PSSP P + S +S P TP +
Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTS 1857
Query: 950 -RDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSS 1004
+ T+ ++ P Y T + S S +T P +S
Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTS 1913
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 51.6 bits (122), Expect = 4e-06
Identities = 109/481 (22%), Positives = 182/481 (37%), Gaps = 84/481 (17%)
Query: 454 DPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTRE 513
D ++ +E++ + + A DG PG T L ++ + P
Sbjct: 1068 DENDLEEDVDSEPAEIEGEAAEDGDPG-----DTGAELDDDQHWSDSPS----------- 1111
Query: 514 VNRDQGRSFP-PKEVKSQTELR------KTPVSE-------ARKTPVTQTPTQASNSQFI 559
+ D+ P P E +++ ELR K P S ++ T ++P Q S FI
Sbjct: 1112 -DADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSP-QESALLFI 1169
Query: 560 PIHHPGA----FPPLPSRPGFPPPTY-VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS 614
P+H P PP+P+ P + P P+ P+ + HS
Sbjct: 1170 PVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKA--------VHS 1221
Query: 615 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 674
P +Q ++ P S P P P + PPS P+ S P QP+ ++T
Sbjct: 1222 PIRSQPVTLPEARTPVS---PGSPQPQPPVAASTPPPSPLPICSQP-QPSTEAT------ 1271
Query: 675 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 734
+ QSP + PA K+ + Q+D +L +P V L + V++ +++
Sbjct: 1272 -VPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEE-FWM 1329
Query: 735 QTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRS 794
++ + + + P+++ P P P P+ V + S D
Sbjct: 1330 KSAEIRR---------SLGLTPVDRSKGPEPSFP---TPAFRPVSLKSYSVEKSPQDEGL 1377
Query: 795 VMAQQANIDRRGKRSPGVFRPEQDPV----PRMPFEKSLLEKPSELMS-HSSSFLSLTGF 849
+ + +I +R G+ +PE +P+ PR P ++ L E SSS L L G
Sbjct: 1378 HLLKPLSIPKR----LGLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGS 1433
Query: 850 SLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSL-YSLFEGTPWS----PSLPA 904
S N + + S FN LT S P + +L L E P + P LPA
Sbjct: 1434 SSNMKTLGSQS-FNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPA 1492
Query: 905 S 905
+
Sbjct: 1493 T 1493
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 50.8 bits (120), Expect = 7e-06
Identities = 52/190 (27%), Positives = 64/190 (33%), Gaps = 22/190 (11%)
Query: 569 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ-----AG 623
P+ P PPP ++ PPP + G P G P Q +P G+ V G
Sbjct: 412 PMQHNPNGPPPPWMQPPPPPMNQG---PHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKG 468
Query: 624 KQSHIPYSQQRPSGPGPMNQGPQQSQ---PPSQQPLTSLPAQPTAQSTSQLQVQALTQQQ 680
P P P P Q P PP QQ P P S+ QQ
Sbjct: 469 MMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
Query: 681 QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPI 740
+ T G PP +QQ Q A A+ PQ+QG P P Q P+
Sbjct: 529 TTTTTTSAGTGSIPP----WQQQQAAAAASP--GAPQMQG-----NPTMVPLPPGVQPPL 577
Query: 741 KLFEPSLQPP 750
P PP
Sbjct: 578 PPGAPPPPPP 587
Score = 31.6 bits (70), Expect = 4.1
Identities = 19/43 (44%), Positives = 21/43 (48%), Gaps = 6/43 (13%)
Query: 550 PTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMG 592
P N +P+ PG PPLP PG PPP PPP S G
Sbjct: 558 PQMQGNPTMVPLP-PGVQPPLP--PGAPPPP---PPPPPGSAG 594
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 50.8 bits (120), Expect = 7e-06
Identities = 88/366 (24%), Positives = 125/366 (34%), Gaps = 57/366 (15%)
Query: 421 GKWIADNQPRLIQCENEVGKLLFI----TEIPELILEDPSEAKENLILQETSVIESLAAD 476
GK I N+ +VG +FI EI E +L D A +ILQ ++
Sbjct: 81 GKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAF-GVILQTPKIMRDPDTG 139
Query: 477 GSPGLKSVLSTSRNLSNN----------CDTGEKPVVTFKENIKTREVNRDQGRSFPPKE 526
S G + S + S+ C+ FK++ K R +
Sbjct: 140 NSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQN 199
Query: 527 VKSQTELRKTPVSEARKTPVTQTPTQASNSQFIP---IHHPGAFPPLPSRPGFPPPTY-- 581
SQ + ++A P P +S +P + PG+FPP PG PP
Sbjct: 200 PLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPP 259
Query: 582 VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHS-----PAGNQVQAGKQSHIPYSQQRPS 636
+PPP +G+ P PG HS P G G S + + P
Sbjct: 260 AMPPPPMPPGAAGHG-PPSAGTPGAGHPGHGHSHPHPFPPGGMPHPG-MSQMQLAHHGPH 317
Query: 637 GPGPMNQGPQQS--QPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK-- 692
G G + GP S QPP + P P P P +P G
Sbjct: 318 GLGHPHAGPPGSGGQPPPRPP----PGMP---------------HPGPPPMGMPPRGPPF 358
Query: 693 -SPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPV 751
SP H G + PP + P G P + P Y + P+ P+ +PPV
Sbjct: 359 GSPMGHPGPMP------PHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPV 412
Query: 752 MQQQPL 757
+ PL
Sbjct: 413 PPRGPL 418
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 50.8 bits (120), Expect = 7e-06
Identities = 89/384 (23%), Positives = 134/384 (34%), Gaps = 46/384 (11%)
Query: 584 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 643
PPP M + P T LQ A Q Q +Q + QQ+ + Q
Sbjct: 129 PPPGTSGMAPHSMAVVSTATPQTQLQ--LQQVALQQQQQQQQ----FQQQQQAALQQQQQ 182
Query: 644 GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQY 703
QQ Q +QQ Q Q QLQ Q QQQQ K HH QQ
Sbjct: 183 QQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ--QQQQQHLIKL---------HHQNQQQI 231
Query: 704 QQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 763
QQ +QL Q+Q L + +Q Q Q ++ P QPP+ Q QP + P
Sbjct: 232 QQ--QQQQLQRIAQLQ--LQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP 287
Query: 764 FPMEPYNHNPSEVKVPEFYWDSSYSMADNR----SVMAQQANIDRRGKRSPGVFRPEQDP 819
++ +H P+ +A N+ +Q + + + PG Q P
Sbjct: 288 QQLQQMHHTQHHQPPPQ---PQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPP 344
Query: 820 ---------VPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSM-----FNEV 865
V + P + + ++ + + + ++ + G + E M F
Sbjct: 345 LKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPT 404
Query: 866 YGKNLTSSSKAEL--SPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSS 923
+ SS L P ++SL L +P + P SP PSS
Sbjct: 405 TAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSP-GQQVQTPQSMPPPPQPSPQPGQPSS 463
Query: 924 LPSSPPTHNHNSVPFSNFGPIGTP 947
P+S + P S+F P +P
Sbjct: 464 QPNSNVSSGPAPSP-SSFLPSPSP 486
Score = 36.6 bits (83), Expect = 0.13
Identities = 47/166 (28%), Positives = 63/166 (37%), Gaps = 6/166 (3%)
Query: 599 AGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGP-GPMNQGPQQS-QPP---SQ 653
A VS P LQ PA G P G G M Q S QPP S
Sbjct: 76 ASVSDPMNALQSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSG 135
Query: 654 QPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLW 713
S+ TA +QLQ+Q + QQQ + ++ QQ QQ ++Q
Sbjct: 136 MAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSA 195
Query: 714 NPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEK 759
Q Q + + ++Q Q Q IKL + Q QQQ L++
Sbjct: 196 MQQQFQAVVQQQQQLQQQQQ-QQQHLIKLHHQNQQQIQQQQQQLQR 240
Score = 31.2 bits (69), Expect = 5.3
Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 15/143 (10%)
Query: 610 PTAHSPAGNQVQAG-KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQST 668
P++ P G Q A QS +P S P P QQ Q P P P+ Q +
Sbjct: 411 PSSSIPLGRQPMAQVSQSSLPML----SSPSP----GQQVQTPQSMPPPPQPSPQPGQPS 462
Query: 669 SQLQVQALTQQQQSPTKAVPALGKSP---PHHSGFQQYQQADASKQL---WNPPQVQGPL 722
SQ + SP+ +P+ P P + Q + L NP V P
Sbjct: 463 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 522
Query: 723 GKIMPVKQPYYLQTQDPIKLFEP 745
G +Q Y + + K EP
Sbjct: 523 GSSQAEEQQYLDKLKQLSKYIEP 545
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 50.1 bits (118), Expect = 1e-05
Identities = 58/205 (28%), Positives = 76/205 (37%), Gaps = 30/205 (14%)
Query: 524 PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVI 583
P+ + S T + P S+A PTQ Q P+ PP P P P
Sbjct: 505 PQRLPSPTSAPQQPASQAAP------PTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQA 558
Query: 584 PPPVAFSMGS---------GYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYS--- 631
PP A S P G G +P PAG QA + +P +
Sbjct: 559 GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP--GPAGPTRQASQAGPVPRTGPP 616
Query: 632 ---QQRPSGPGPMNQ-GPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAV 687
Q RPSGPGP + PQ +Q PSQ +P TA + Q + QS T A
Sbjct: 617 TTQQPRPSGPGPAGRPKPQLAQKPSQ----DVPPPATAAAGGPPHPQ--LNKSQSLTNAF 670
Query: 688 PALGKSPPHHSGFQQYQQADASKQL 712
+PP S Q +A+ + L
Sbjct: 671 NLPEPAPPRPSLSQDEVKAETIRSL 695
Score = 41.2 bits (95), Expect = 0.005
Identities = 56/186 (30%), Positives = 67/186 (36%), Gaps = 37/186 (19%)
Query: 569 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 628
P P R G PP PPP SG PAG +P PT+ +P QA +
Sbjct: 472 PGPQRQG--PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTS-APQQPASQAAPPTQG 528
Query: 629 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 688
Q RP GP PP+ +P PA P+ Q Q T+Q A P
Sbjct: 529 QGRQSRPVAGGP-------GAPPAARP----PASPSPQ--RQAGPPQATRQTSVSGPAPP 575
Query: 689 ALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQ 748
+PP G QQ Q PP Q P G P +Q P+ P
Sbjct: 576 KASGAPP---GGQQRQ---------GPP--QKPPGPAGPTRQ---ASQAGPV----PRTG 614
Query: 749 PPVMQQ 754
PP QQ
Sbjct: 615 PPTTQQ 620
Score = 38.5 bits (88), Expect = 0.033
Identities = 48/192 (25%), Positives = 64/192 (33%), Gaps = 37/192 (19%)
Query: 621 QAGKQSHIPYSQQRPS--------GPGPMNQGPQQSQ--------------PPSQQPL-- 656
Q +Q P +QQRP GPGP QGP Q PP+ PL
Sbjct: 447 QTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQ 506
Query: 657 -----TSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQ 711
TS P QP +Q+ Q Q + + P + P S +Q A++Q
Sbjct: 507 RLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQ 566
Query: 712 LWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ---PLEKKMKPFPMEP 768
V GP P Q Q P + P P Q P+ + P +P
Sbjct: 567 ----TSVSGPAPPKASGAPPGGQQRQGPPQK-PPGPAGPTRQASQAGPVPRTGPPTTQQP 621
Query: 769 YNHNPSEVKVPE 780
P P+
Sbjct: 622 RPSGPGPAGRPK 633
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 49.7 bits (117), Expect = 1e-05
Identities = 75/327 (22%), Positives = 121/327 (37%), Gaps = 43/327 (13%)
Query: 569 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 628
P+P +PG P + PP ++ PA +Q AG Q +AG
Sbjct: 2099 PIPGQPGMPQGQPGLQPPTMPGQQGVHSNPA--------MQNMNPMQAGVQ-RAGLPQQQ 2149
Query: 629 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVP 688
P Q +P G Q Q + + P +Q L+ Q + QQQQ A P
Sbjct: 2150 PQQQLQPPMGGMSPQAQQMNMNHNTMP---------SQFRDILRRQQMMQQQQQQG-AGP 2199
Query: 689 ALGKSPPHHSGFQQYQ------QADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKL 742
+G +H+ FQQ Q Q Q QG +G+I + Q + ++
Sbjct: 2200 GIGPGMANHNQFQQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQA 2259
Query: 743 FEPSLQPPVMQQQPLEKKMKPFPMEPYNHN-PSEVKVPEFYWDSSYSMADNRSVMAQQAN 801
++ L QQ + ++P PM P H P++ + P + N+ V + Q
Sbjct: 2260 YQQRL-----LQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQ-VRSPQPV 2313
Query: 802 IDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPN--- 858
R + P P P PRM + S + S ++ + Q + +
Sbjct: 2314 PSPRPQSQP----PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQ 2369
Query: 859 NSMFNEVYGK----NLTSSSKAELSPS 881
NSM +++ NL +S +L S
Sbjct: 2370 NSMLSQLASNPGMANLHGASATDLGLS 2396
Score = 47.0 bits (110), Expect = 9e-05
Identities = 81/331 (24%), Positives = 117/331 (35%), Gaps = 77/331 (23%)
Query: 535 KTPVSEARKTPVT---QTPTQASNSQFIPIH---------HPGAFPPLPSRPGFPPPTYV 582
+ PVS+A+ + + +P SQ IH H + P+PSR P T
Sbjct: 788 QAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHT-- 845
Query: 583 IPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMN 642
PP + T PA V P PA + G QS + R + P
Sbjct: 846 -PPSIGAQQPPATTIPAPVPTP----------PA---MPPGPQSQALHPPPRQTPTPPTT 891
Query: 643 QGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQ 702
Q PQQ QP SLPA A S Q Q Q +QQ + + P PP +
Sbjct: 892 QLPQQVQP-------SLPA---APSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLS 941
Query: 703 YQQADASKQLWNPPQVQGP--LGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKK 760
Q+ NPP + + KQP Q+ +E K
Sbjct: 942 QPAVSIEGQVSNPPSTSSTEVNSQAIAEKQP--------------------SQEVKMEAK 981
Query: 761 MKPFPMEPYNHNP---SEVKVPEFYWDSSYS-------------MADNRSVMAQQANIDR 804
M+ EP + P SE KV + +S+ + D S A Q++
Sbjct: 982 MEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSS-PA 1040
Query: 805 RGKRSPGVFRPEQDPVPRMPFEKSLLEKPSE 835
G+ +F+PE+ MP ++L + E
Sbjct: 1041 PGQSKKKIFKPEELRQALMPTLEALYRQDPE 1071
Score = 42.0 bits (97), Expect = 0.003
Identities = 44/154 (28%), Positives = 58/154 (37%), Gaps = 22/154 (14%)
Query: 621 QAGKQSHIPYSQQRPSGPGPMN-QGPQQSQPPSQQPLTSLP--------AQPTAQSTSQL 671
Q G S P + P+G P Q PQ + P P S+P A P +Q +
Sbjct: 1844 QQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAG 1903
Query: 672 QVQALTQQQQSPTKAVPALGKSPPH--HSGFQQYQQADASKQLWNPPQVQGPLGKIMPVK 729
QV T P A P L PP Q + A+ +Q+ + Q P+ MP
Sbjct: 1904 QVTPPTP----PQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPM 1959
Query: 730 QPYYLQ-------TQDPIKLFEPSLQPPVMQQQP 756
P T+ P EP + P MQQQP
Sbjct: 1960 TPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQP 1993
Score = 41.6 bits (96), Expect = 0.004
Identities = 76/355 (21%), Positives = 116/355 (32%), Gaps = 82/355 (23%)
Query: 393 DFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELIL 452
D S Q G RR+ QR I + QC N L
Sbjct: 1714 DESNNQQAAATQSPGDSRRLSIQRCIQ-------SLVHACQCRNANCSL----------- 1755
Query: 453 EDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPV---VTFKENI 509
PS K ++Q T + G P K +++ + +C + PV + K+ +
Sbjct: 1756 --PSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKL 1813
Query: 510 KTREV-NRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFP 568
+ +++ +R Q + + S + +P TPT + Q
Sbjct: 1814 RQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQ----------- 1862
Query: 569 PLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHI 628
P+ P P PT P P + P + QA
Sbjct: 1863 --PTTPQTPQPTSQPQPT----------------------PPNSMPPYLPRTQAAG---- 1894
Query: 629 PYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ--ALTQQQQSPTKA 686
P SQ + +G PQ +QPP LP P A +Q+Q A TQ+Q + +
Sbjct: 1895 PVSQGKAAGQVTPPTPPQTAQPP-------LPGPPPAAVEMAMQIQRAAETQRQMAHVQI 1947
Query: 687 V--PALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDP 739
P + PP A + PP +GP G + P P +Q Q P
Sbjct: 1948 FQRPIQHQMPP--------MTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPP 1994
Score = 33.1 bits (74), Expect = 1.4
Identities = 44/168 (26%), Positives = 58/168 (34%), Gaps = 18/168 (10%)
Query: 625 QSHIPYSQQRPSGPGPMNQGPQQSQPPSQ---QPLTSLPAQ-------PTAQSTSQLQV- 673
Q H +Q P PM GP+ QP +Q P T P+Q P A S+ Q V
Sbjct: 734 QHHGQLAQPGALNP-PMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVS 792
Query: 674 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMP----VK 729
QA P + S H Q Q + +P + P P +
Sbjct: 793 QAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQ 852
Query: 730 QPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVK 777
QP T P + P PP Q Q L + P P P +V+
Sbjct: 853 QP--PATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQ 898
Score = 31.6 bits (70), Expect = 4.1
Identities = 35/117 (29%), Positives = 43/117 (36%), Gaps = 12/117 (10%)
Query: 616 AGNQVQAGKQSHIPY--SQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQV 673
AGN + Q P Q GP P+ G + P P T P Q S LQ+
Sbjct: 215 AGNLLTEPLQQGSPQMGGQTGLRGPQPLKMGMMNNPNPYGSPYTQNPGQQIGASGLGLQI 274
Query: 674 QALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQ 730
Q T+ S + A+ K G Q A PQVQ P G + PV Q
Sbjct: 275 Q--TKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPA-------PQVQQP-GLVTPVAQ 321
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 49.7 bits (117), Expect = 1e-05
Identities = 43/119 (36%), Positives = 49/119 (41%), Gaps = 19/119 (15%)
Query: 545 PVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVP 604
P QTP + P+ PG PP P PG PPP V+PPP+A G P V P
Sbjct: 231 PAGQTPPRP------PLGPPG--PPGP--PGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280
Query: 605 GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQP 663
G QP P G + G +P P GP P PQQ PP P P P
Sbjct: 281 G---QPFGQPPLG-PLPPGPPPPVP-GYGPPPGPPP----PQQGPPPPPGPFPPRPPGP 330
Score = 33.5 bits (75), Expect = 1.1
Identities = 34/138 (24%), Positives = 43/138 (31%), Gaps = 11/138 (7%)
Query: 524 PKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVI 583
P + Q L P P P Q P PG FPP P P PP T
Sbjct: 280 PGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339
Query: 584 PPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQ 643
PP + P G P + P P N S P P P ++
Sbjct: 340 PPHLPGP-------PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR 392
Query: 644 G----PQQSQPPSQQPLT 657
G P + ++ PL+
Sbjct: 393 GDYGPPGREMDTARTPLS 410
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 49.7 bits (117), Expect = 1e-05
Identities = 77/343 (22%), Positives = 126/343 (36%), Gaps = 67/343 (19%)
Query: 622 AGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQ 681
+ +Q QQ+ Q QQ Q PS QP SLP+QP +S LQ + L QQ Q
Sbjct: 637 SAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696
Query: 682 SPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPY----YLQTQ 737
+ P G+Q QQ Q Q GP P P Y+ +Q
Sbjct: 697 N----------QPIAGMGYQVSQQ-QRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745
Query: 738 DPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMA 797
+ + + +Q+Q +E+K + + M + +A
Sbjct: 746 QSLLNQQLMGKKQTLQRQIMEQKQQLLLQQ--------------------QMLADAEKIA 785
Query: 798 QQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYP 857
Q I+R R P ++ ++ V M +P+ S SS +SL
Sbjct: 786 PQDQINRHLSRPPPDYKDQRRNVGNM--------QPTAQYSGGSSTISLNS--------- 828
Query: 858 NNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDH----STPAS 913
N ++ N V + + + + LS S + SL + + +LP + + ++ +
Sbjct: 829 NQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMN 888
Query: 914 QSPHSSNPSSLPSS--------PPT---HNHNSVPFSNFGPIG 945
Q NP L ++ PPT N+N+V G +G
Sbjct: 889 QLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVG 931
Score = 36.2 bits (82), Expect = 0.17
Identities = 73/355 (20%), Positives = 120/355 (33%), Gaps = 62/355 (17%)
Query: 455 PSEAKENLILQ-ETSVIESLAADGSPGLKSVLS-TSRNLSNNCDTGEKPVVTFKENIKTR 512
PS E ++++ E S + GSP L+ + + +++N+ + P+ + ++
Sbjct: 355 PSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQP 414
Query: 513 EVNRDQGRSFPP-KEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLP 571
+ R+ P +EV +L++ + + + Q Q H P + LP
Sbjct: 415 QTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQ---------HQPTNWSALP 465
Query: 572 SRPGFPPPTY---VIPPPV--------------AFSMGSG-------YTFPAGVSVPGTF 607
S G P + IP P + GSG Y + AG S G
Sbjct: 466 SSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGH 525
Query: 608 LQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPM---NQGPQQSQPPSQQPLTSLPA--- 661
L + ++ + P + R P+ N Q PS P + P+
Sbjct: 526 LDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLH 585
Query: 662 ---QPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQV 718
Q Q Q Q Q QQQQ QQ QQ +Q Q
Sbjct: 586 YTQQQQQQQQQQQQQQQQQQQQQQQ-----------------QQQQQQQQQQQSSISAQQ 628
Query: 719 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNP 773
Q + +Q Q Q + + Q QQQP + + P +P +P
Sbjct: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 49.7 bits (117), Expect = 1e-05
Identities = 128/544 (23%), Positives = 183/544 (33%), Gaps = 91/544 (16%)
Query: 559 IPIHHP-GAFPPLPSRPGFP--PPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSP 615
+P P G P P P FP PPTY PP G+ PA + G +P A P
Sbjct: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTY---PPYPSPTGA----PAQPPMLGASSRPGAGQP 2223
Query: 616 AG-NQVQAGKQSHIPYSQQ---RPSGPGPMN----QGPQQSQPPSQQPLTSLPAQPTAQS 667
+ G H P + +P P N + P + +PL S P P +S
Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPP--PFGES 2281
Query: 668 TSQLQVQALTQQQQSPTKAVPALG----KSPPHHSGFQQYQQADASKQLWNP------PQ 717
L+V+ SP+ P LG S H G + + D K P PQ
Sbjct: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQ 2341
Query: 718 VQG--------PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVM---QQQPLEK----KMK 762
G P + + P + P +P QPP+ Q P E +
Sbjct: 2342 SPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPR 2401
Query: 763 PFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQ---ANIDRRGKRSPGVFRPEQDP 819
P +P++ P+ + SS S R + A+ + + R + RP P
Sbjct: 2402 SLPSDPFSRVPASPQSQS----SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP 2457
Query: 820 VPRMPFEKSLLEKPSELMSHSSSFL--SLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAE 877
R PF L KP +F SL SL +P L + E
Sbjct: 2458 QSRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFP----------AALPAGPAGE 2505
Query: 878 LSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTP-ASQSPHSSNPSSLPSSPPTHNHNSV 936
L + + + GT P+ + P A P P P PP H NS
Sbjct: 2506 LHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINS- 2564
Query: 937 PFSNFGP---IGTPDNRDRRTAD-----RWKTDKPAMGGFGIDY-LSATSSSESSWHQAS 987
+FGP +G P + + A P+ G G Y LS A
Sbjct: 2565 ---HFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621
Query: 988 TPSGTWTGHGPSM-----------EDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQ 1036
S + HG S ED + SL + PG S L Q +++++
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681
Query: 1037 KQQR 1040
++QR
Sbjct: 2682 QRQR 2685
Score = 48.5 bits (114), Expect = 3e-05
Identities = 79/345 (22%), Positives = 120/345 (34%), Gaps = 35/345 (10%)
Query: 452 LEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSN-NCDTGEKPVVTFKENIK 510
L P E+ L+E+ + + SP L++ LS S + E P+ E +
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP 562
Query: 511 TREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPL 570
T S PP+E ++P+S + P + S P P + PP
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 571 PSR--------PGFPPP-TYVIPPPVAFSMGSGYTFPAGVSVP---GTFLQPTAHSPAGN 618
SR P PPP + PP S S + +S P P SP
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682
Query: 619 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 678
+A + S P + P+ P P + + PP + L SLP + + + Q +
Sbjct: 683 PPEASRLS--PPPEDSPTSPPPED---SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR 737
Query: 679 QQ---QSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNP------------PQVQGPLG 723
+ SP P L P Q ++ S Q P PQ +GP
Sbjct: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP-- 795
Query: 724 KIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEP 768
+ P + +L Q P + P + QP E + P EP
Sbjct: 796 HLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840
Score = 44.7 bits (104), Expect = 5e-04
Identities = 77/327 (23%), Positives = 118/327 (36%), Gaps = 57/327 (17%)
Query: 620 VQAGKQSHIPYSQQRPSGP----GPMNQGPQQS--QPPSQQPLTSLPAQPTAQSTSQLQV 673
VQ Q P +++ P P P++ P++S PP + S P + S +
Sbjct: 424 VQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEAL 483
Query: 674 QALTQQQQSPTKAVPALG--KSPPHHSGFQQYQQADASKQLWNPPQ--VQGPLG---KIM 726
++SP P PP S F +++ S +PP ++ PL +
Sbjct: 484 HLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS 543
Query: 727 PVKQPYYLQTQDPIKLFEPSLQPPV---MQQQPLEKKMKPFPME-PYNHNPSEVKVPEFY 782
P+ P+ P P+ PP + P E M P P E P + P ++ +
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603
Query: 783 WDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSS 842
+S S S ++ R SP PE P+ P E+S + P E+ S
Sbjct: 604 EESPLSPPPEESPLSPPPEASRL---SPP---PEDSPMSPPP-EESPMSPPPEVSRLSPL 656
Query: 843 FLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSL 902
+ + LSP P+E+ L E +P SP
Sbjct: 657 PVV------------------------------SRLSPP--PEESPLSPPPEESPTSPP- 683
Query: 903 PASSDHSTPASQSPHSSNPSSLPSSPP 929
P +S S P SP S P P+SPP
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPP 710
Score = 43.9 bits (102), Expect = 8e-04
Identities = 100/438 (22%), Positives = 141/438 (32%), Gaps = 89/438 (20%)
Query: 523 PPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYV 582
PP+ ++P+S + T P +AS P P + PP S PP
Sbjct: 539 PPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR 598
Query: 583 IPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMN 642
+ PP S S P SP +A + S P + P P P
Sbjct: 599 LFPPFEESPLS---------------PPPEESPLSPPPEASRLS--PPPEDSPMSPPP-- 639
Query: 643 QGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGK-SPPHHSGFQ 701
+ S PP L+ LP + S + ++SPT P + SPP
Sbjct: 640 EESPMSPPPEVSRLSPLPV-VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698
Query: 702 QYQQADA------SKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQ 755
D+ L + P + PL +P+ + L + P + P + +
Sbjct: 699 SPPPEDSPASPPPEDSLMSLPLEESPL---LPLPEEPQLCPRSEGPHLSPRPEEPHLSPR 755
Query: 756 PLEKKMKPFPMEPY----NHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPG 811
P E + P EP+ P VPE S + + S ++ ++ SP
Sbjct: 756 PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHL------SPQ 809
Query: 812 VFRPEQDPVPRMPF---------------EKSLLEKPSELMSHSSSFLSLTGFSLNQERY 856
P PVP P E L +P E SH S L S E+
Sbjct: 810 TEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE--SHLSPELEKPPLSPRPEKP 867
Query: 857 PNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSL------PASSDHST 910
P E AP+E L+ P PSL PA S+
Sbjct: 868 PE------------------EPGQCPAPEELPLFP----PPGEPSLSPLLGEPALSEPGE 905
Query: 911 PASQSPHSSNPSSLPSSP 928
P P S P LP SP
Sbjct: 906 P----PLSPLPEELPLSP 919
Score = 42.4 bits (98), Expect = 0.002
Identities = 61/229 (26%), Positives = 86/229 (37%), Gaps = 23/229 (10%)
Query: 744 EPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANID 803
EP L+ P+ ++ PL + P+ P PE S S + + ++
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486
Query: 804 RRGKRSPGVFRPEQDPV-------PRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERY 856
R + SP PE+ P+ P P E+S L P E S S L T S E
Sbjct: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE--SPPSPALE-TPLSPPPEAS 543
Query: 857 PNNSMFNEVY----GKNLTSSSKAELSP-SMAPQETSLYSLFEGTPWSPSLPAS------ 905
P + F E + L +S E S S P+E+ + E +P SP AS
Sbjct: 544 PLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603
Query: 906 --SDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDR 952
S S P +SP S P + SPP + P P+ P R
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Score = 33.9 bits (76), Expect = 0.83
Identities = 57/264 (21%), Positives = 96/264 (36%), Gaps = 23/264 (8%)
Query: 507 ENIKTREVNRDQGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGA 566
E+ T D S PP++ L P+ E+ P+ + P S+ +
Sbjct: 694 EDSPTSPPPEDSPASPPPED-----SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748
Query: 567 FPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGT-FLQPTAH----SPAGNQVQ 621
P L RP P ++ P + P +VP L P A SP ++
Sbjct: 749 EPHLSPRPEEP---HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
Query: 622 AGKQSHIPYSQQRPSGPGPMNQGPQQSQ--PPSQQPLTSLPAQPTAQSTSQLQVQALTQQ 679
Q+ P+ P P ++ P++S P S++P S P + + +L+ L+ +
Sbjct: 806 LSPQTEEPHLSPVPEEPC-LSPQPEESHLSPQSEEPCLS-PRPEESHLSPELEKPPLSPR 863
Query: 680 QQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDP 739
+ P + P +P F + S L P + + P+ + L
Sbjct: 864 PEKPPEE-PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG- 921
Query: 740 IKLFEPSLQPPVMQQQPLEKKMKP 763
EPSL P +M PL + P
Sbjct: 922 ----EPSLSPQLMPPDPLPPPLSP 941
Score = 32.7 bits (73), Expect = 1.8
Identities = 51/179 (28%), Positives = 62/179 (34%), Gaps = 20/179 (11%)
Query: 619 QVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQ 678
Q Q +Q + QQ+ Q Q Q QQ L Q Q QLQ Q Q
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQ 3962
Query: 679 ----QQQSPTKAVPALGKSPPHHSGFQQYQQADA--------SKQLWNPPQVQGPLGKIM 726
QQQ + + L +S S QQ QQ A Q ++ P GP +
Sbjct: 3963 QQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLT 4022
Query: 727 PVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDS 785
+Q T DP E + P Q PL P E P EVK P DS
Sbjct: 4023 GKEQ----NTVDPAVSSEATEGPSTHQGGPLAIGTTP---ESMATEPGEVK-PSLSGDS 4073
Score = 32.0 bits (71), Expect = 3.1
Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 17/128 (13%)
Query: 604 PGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPP----SQQPLTSL 659
PGT P G Q Q G + G GP QGP + P S P+
Sbjct: 4246 PGTQTSPL-QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG- 4303
Query: 660 PAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQ 719
P PT +S Q Q SP+ +P + PP H G + Q P ++
Sbjct: 4304 PVHPTPPPSSP-QEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQ----------GPTLE 4352
Query: 720 GPLGKIMP 727
P G++ P
Sbjct: 4353 PPPGRVSP 4360
Score = 31.6 bits (70), Expect = 4.1
Identities = 40/164 (24%), Positives = 54/164 (32%), Gaps = 4/164 (2%)
Query: 563 HPGAFPPL-PSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQ 621
HPGA P P R + V+ P G G V+ Q H G+
Sbjct: 3814 HPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQ-QQQQQHQQQGSMAG 3872
Query: 622 AG--KQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQ 679
+QS + +S Q PM Q Q Q L Q Q Q Q+Q Q
Sbjct: 3873 LSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQ 3932
Query: 680 QQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLG 723
QQ + + + Q QQ +Q + Q Q +G
Sbjct: 3933 QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976
Score = 30.8 bits (68), Expect = 7.0
Identities = 61/249 (24%), Positives = 88/249 (35%), Gaps = 36/249 (14%)
Query: 525 KEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR-PGFPPPTYVI 583
K+ K T L ++ ++ Q Q +S + + P P L ++ PG P + +
Sbjct: 3583 KQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALS-PSQSPRLLTKLPGQLLPGHGL 3641
Query: 584 PPPVAFSMGSGYTF---PAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGP 640
PP G P G+++PG P ++ Q Q QQ G G
Sbjct: 3642 QPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQ----------QQHSGGAGS 3691
Query: 641 MNQGPQQSQPPSQQPLTSLPA-------------QPTAQSTSQLQVQALTQQQQSPTKAV 687
+ GP P L SL Q Q +LQ Q QQQQ
Sbjct: 3692 L-AGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQ 3750
Query: 688 PALGKSPPHHSGFQQYQQADASKQ-LWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS 746
A+ + G Q Q Q L P QG L + + + P Q P + P+
Sbjct: 3751 VAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPP-----QGPQGMLGPA 3805
Query: 747 LQPPVMQQQ 755
Q V+QQQ
Sbjct: 3806 -QVAVLQQQ 3813
Score = 30.8 bits (68), Expect = 7.0
Identities = 97/437 (22%), Positives = 148/437 (33%), Gaps = 93/437 (21%)
Query: 542 RKTPVTQTP-TQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSG------ 594
R+TP Q P TQ S Q G P GFP P P+ +G+G
Sbjct: 4238 RQTPPYQEPGTQTSPLQ-------GLLGCQPQLGGFPGPQ---TGPLQ-ELGAGPRPQGP 4286
Query: 595 --YTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSG-PGPMNQGPQQSQPP 651
P G G L P +P + P +RPS P P +Q P ++Q P
Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSS---------PQEPKRPSQLPSPSSQLPTEAQLP 4337
Query: 652 SQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQ 711
P T P PT + A Q + T LG P + + + +S
Sbjct: 4338 PTHPGTPKPQGPTLEPPPGRVSPAAA--QLADTLFSKGLGPWDPPDNLAETQKPEQSSLV 4395
Query: 712 LWNPPQVQG---PLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPM-- 766
+ QV G P + +KQ EP +P + Q ++++ P+
Sbjct: 4396 PGHLDQVNGQVVPEASQLSIKQ-------------EPREEPCALGAQSVKREANGEPIGA 4442
Query: 767 -EPYNH--------NPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRR--------GKRS 809
NH + + + + ++ R +A I+ ++
Sbjct: 4443 PGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKL 4502
Query: 810 PGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKN 869
G ++D R P L KP + S +S S + R + +E K
Sbjct: 4503 QGTPSNKEDAAARKP----LTPKPKRVQKASDRLVS----SRKKLRKEDGVRASEALLKQ 4554
Query: 870 LTSSSKAELSPSMAPQETSLYSLF---------------EGTPWSPSLPASSDHSTPASQ 914
L + L P P T+ +SLF G S +LP D+ +
Sbjct: 4555 L--KQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLT 4612
Query: 915 SPHSSNPSSLPSS-PPT 930
+ SNP + PSS PPT
Sbjct: 4613 KNNLSNPPTPPSSLPPT 4629
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 48.9 bits (115), Expect = 2e-05
Identities = 75/279 (26%), Positives = 93/279 (33%), Gaps = 42/279 (15%)
Query: 524 PKEVKSQTELRKTPVSEARKT-PVTQTPTQASNSQFIPIHHPGAFPP-LPSRPGFPPP-- 579
P+ VK+ K +AR T P+ T T + Q P LP +P P
Sbjct: 334 PEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKR 393
Query: 580 TYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSG-- 637
V PPP A + A V P P+ P Q QA + P QQ PS
Sbjct: 394 ATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLP---QTQAKQPQAPPTPQQTPSTQA 450
Query: 638 ---PGPMNQGPQQSQP----PSQQPLTSLPAQPTAQSTSQLQVQALTQQQQS--PTKAVP 688
P PQ Q QQ PAQ T Q QA TQQ Q+ P P
Sbjct: 451 QGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQP 510
Query: 689 ALGKSPPHHSGFQQ-------YQQADASKQLWNPPQV-----------------QGPLGK 724
A+ + P G Q YQQ +Q Q+ Q P
Sbjct: 511 AIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMA 570
Query: 725 IMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKP 763
QP P EP++Q PV QQ ++ P
Sbjct: 571 AGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPP 609
Score = 45.1 bits (105), Expect = 4e-04
Identities = 53/214 (24%), Positives = 73/214 (34%), Gaps = 16/214 (7%)
Query: 523 PPKEVKSQTELRKTPVSEA-RKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTY 581
PP + QT+ ++ ++TP TQ + +Q P H F + PPP
Sbjct: 423 PPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQ 482
Query: 582 VIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPM 641
P + T P T A P +Q + +Q + QQ
Sbjct: 483 QQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQ-------- 534
Query: 642 NQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQ---VQALTQQQQSPTKAVPALGKSPPHHS 698
Q QQ Q QQ T+L Q + LQ A QQ Q A P +P
Sbjct: 535 -QQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQ--PAPAQEP 591
Query: 699 GFQQYQQADASKQLWNPPQVQG-PLGKIMPVKQP 731
Q + Q PP VQG +G + P P
Sbjct: 592 AIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSP 625
>gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]
Length = 463
Score = 48.9 bits (115), Expect = 2e-05
Identities = 67/291 (23%), Positives = 94/291 (32%), Gaps = 30/291 (10%)
Query: 541 ARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG 600
A T P Q P+ PG PP+P PG PP + P V M G
Sbjct: 122 AASTSFQPQPVQPQQGYIPPMAQPG-LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
Query: 601 VSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPG--PMNQGPQQSQPPSQQPLTS 658
+ PG H Q G+ +P P GPG P+ G PP P
Sbjct: 181 MP-PGLH-----HQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPG----MPPGMPPPVP 230
Query: 659 LPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQV 718
P P + + + +PT VPA + P F QA A+ V
Sbjct: 231 RPGIPPMTQAQAVSAPGILNRPPAPTATVPA-PQPPVTKPLFPSAGQAQAA--------V 281
Query: 719 QGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKV 778
QGP+G T +P K P+ P P+ +
Sbjct: 282 QGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTT 341
Query: 779 PE-----FYWDSSYSMADNRSVMAQ-QANIDRRGKRSPGVFRPEQDPVPRM 823
+ D S+ + R+ + + Q N+ R G+ G P P+ M
Sbjct: 342 TSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPIGGM 390
Score = 32.3 bits (72), Expect = 2.4
Identities = 47/200 (23%), Positives = 68/200 (34%), Gaps = 28/200 (14%)
Query: 556 SQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGV-SVPGTFLQPTAHS 614
+ F P++ A P +P FP T + + + A + S P T +A S
Sbjct: 287 TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS 346
Query: 615 PAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQ 674
+ I ++R P P+ P Q P+ + P P + Q
Sbjct: 347 KLIHP-----DEDISLEERRAQLPKYQRNLPR----PGQAPIGNPPVGPIG---GMMPPQ 394
Query: 675 ALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYL 734
QQQ +P G+ HH G Y PP QGP P+ PY
Sbjct: 395 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAM------PPYGQGP-----PMVPPYQG 443
Query: 735 QTQDPIKLFEPSLQPPVMQQ 754
P ++PPVM Q
Sbjct: 444 GPPRP----PMGMRPPVMSQ 459
>gi|50345881 cytoplasmic polyadenylation element binding protein 3
[Homo sapiens]
Length = 698
Score = 48.5 bits (114), Expect = 3e-05
Identities = 61/293 (20%), Positives = 94/293 (32%), Gaps = 81/293 (27%)
Query: 517 DQGRSFPPKEVKSQTELRKTP---VSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSR 573
D+ ++ P + + + + + P VSEA TP++ + + +P P A PP P+
Sbjct: 8 DKSKTQPQPQQQQRQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPAAAPPAPNG 67
Query: 574 PGF--------------------PPPTYVIPPPVAFSMGSGYTFPAGVS----------- 602
P PPP P + S G T+ G +
Sbjct: 68 PDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAVEDSFFQGI 127
Query: 603 --VPGTFL--------QPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPS 652
V GT L P Q+ + H Q+P P P Q Q +QPP
Sbjct: 128 TPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQH----HQQPPPPAPAPQPAQPAQPPQ 183
Query: 653 QQP--LTSLPAQPTAQSTSQLQV------QALTQQQQSPTKAVPALGKSPPHHSGFQQYQ 704
QP PA P+ +Q Q + + S + AV A + S +
Sbjct: 184 AQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWN 243
Query: 705 QADASKQLWNPPQ-------------------------VQGPLGKIMPVKQPY 732
+ W+ P V PL I P+K+P+
Sbjct: 244 THQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPF 296
Score = 32.3 bits (72), Expect = 2.4
Identities = 58/278 (20%), Positives = 97/278 (34%), Gaps = 37/278 (13%)
Query: 737 QDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPS---EVKVPEFYWDSSYSMADNR 793
QD + + + QP QQQ ++ +P P + PS + P+ +S+
Sbjct: 2 QDDLLMDKSKTQPQPQQQQ--RQQQQPQPESSVSEAPSTPLSSETPKPEENSAVPALSPA 59
Query: 794 SVMAQQANIDRRGKRSPGV------FRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLT 847
+ D+ SP + P+Q P P+ P PS + S+ +
Sbjct: 60 AAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPAAPGASLSPSFGSTWSTGTTNAV 119
Query: 848 GFSLNQERYP-NNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASS 906
S Q P N +M + + ++ SP + +T + + P +P+ +
Sbjct: 120 EDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQ--QPPPPAPAPQPAQ 177
Query: 907 DHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMG 966
P +Q P + PS P ++ PI T KP+
Sbjct: 178 PAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPI--------------MTSKPSSS 223
Query: 967 GF--GIDYLSATSSSESSW--HQA-----STPSGTWTG 995
+A SS+ SSW HQ+ S PS W G
Sbjct: 224 SAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGG 261
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 48.5 bits (114), Expect = 3e-05
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 7/165 (4%)
Query: 560 PIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAG---VSVPGT-FLQPTAHSP 615
P+ PG PP P P ++ PP + G FP G V+ PGT L PT
Sbjct: 78 PMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIW 137
Query: 616 AGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQA 675
N+ GK + Y+ + G + Q P+ + AQ AQ+ +Q Q QA
Sbjct: 138 VENKTPDGKVYY--YNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQA 195
Query: 676 LTQQQQSPTKAVPALGKSPPHHSGFQQYQ-QADASKQLWNPPQVQ 719
Q Q A ++ Q Q QA A Q Q Q
Sbjct: 196 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 240
Score = 34.3 bits (77), Expect = 0.63
Identities = 58/294 (19%), Positives = 98/294 (33%), Gaps = 38/294 (12%)
Query: 518 QGRSFPPKEVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFP 577
Q ++ +V++Q + + + TP T +P A ++ S P
Sbjct: 234 QAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTS-----------TSSSTPSST 282
Query: 578 PPTYVIPPPVAFSMGS----GYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSH------ 627
T VA ++ + T + VSV + + +P VQ Q H
Sbjct: 283 TSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPP 342
Query: 628 -IPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKA 686
+P+S +P+ P P PP + PL +P Q A
Sbjct: 343 AVPHSVPQPTTAIPAF--PPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVPMIHPQVAIAA 400
Query: 687 VPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPS 746
PA S + +Y+ AD +N ++ K +K+ L+ K+ EP
Sbjct: 401 SPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEE----KIKEPI 456
Query: 747 LQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQA 800
+P +P PME +P E + E + AQ+A
Sbjct: 457 KEP----------SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKA 500
Score = 33.1 bits (74), Expect = 1.4
Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 26/152 (17%)
Query: 564 PGAFPPL--PSRPGFPP----------PTYVIPPPVAFSMGSGYTFPAGVSV-------P 604
P PP+ P P PP P + A + S +T P GV V P
Sbjct: 116 PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTP 175
Query: 605 GTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQ-QPLTSLPAQP 663
Q + A Q QA Q+ Q + Q Q+Q +Q Q AQ
Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 235
Query: 664 TAQSTSQLQVQALTQQQ------QSPTKAVPA 689
AQ+ +Q+Q Q Q Q +PT + PA
Sbjct: 236 QAQAQAQVQAQVQAQVQAQAVGASTPTTSSPA 267
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,911,996
Number of Sequences: 37866
Number of extensions: 2476855
Number of successful extensions: 14998
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 782
Number of HSP's that attempted gapping in prelim test: 10532
Number of HSP's gapped (non-prelim): 3849
length of query: 1049
length of database: 18,247,518
effective HSP length: 113
effective length of query: 936
effective length of database: 13,968,660
effective search space: 13074665760
effective search space used: 13074665760
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.