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Search of human proteins with 41281798
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41281798 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform beta [Homo sapiens]
(462 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41281798 mitogen-activated protein kinase kinase kinase 7 int... 912 0.0
gi|5174703 mitogen-activated protein kinase kinase kinase 7 inte... 857 0.0
gi|13540531 integrin-linked kinase-associated protein phosphatas... 52 1e-06
gi|167466276 protein phosphatase 1K (PP2C domain containing) [Ho... 49 1e-05
gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens] 46 6e-05
gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens] 42 0.002
gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens] 42 0.002
gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens] 42 0.002
gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit ... 40 0.003
gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit... 40 0.003
gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit... 40 0.003
gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit... 40 0.003
gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit... 40 0.003
gi|4505999 protein phosphatase 1G [Homo sapiens] 40 0.003
gi|29826282 protein phosphatase 1G [Homo sapiens] 40 0.003
gi|30089948 protein phosphatase 1E [Homo sapiens] 40 0.004
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 39 0.008
gi|122937199 protein phosphatase 1B-like [Homo sapiens] 38 0.017
gi|171460934 protein phosphatase 1M isoform b [Homo sapiens] 38 0.017
gi|171460932 protein phosphatase 1M isoform a [Homo sapiens] 38 0.017
gi|149944715 protein phosphatase 1H (PP2C domain containing) [Ho... 37 0.038
gi|65506328 protein phosphatase 1J (PP2C domain containing) [Hom... 36 0.084
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 33 0.42
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 33 0.42
gi|91982772 mucin 17 [Homo sapiens] 33 0.71
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 32 0.93
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 32 0.93
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 32 0.93
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 32 0.93
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 32 0.93
>gi|41281798 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform beta [Homo sapiens]
Length = 462
Score = 912 bits (2356), Expect = 0.0
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 1 MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSEN 60
MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSEN
Sbjct: 1 MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSEN 60
Query: 61 NCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLES 120
NCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLES
Sbjct: 61 NCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLES 120
Query: 121 IDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYV 180
IDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYV
Sbjct: 121 IDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYV 180
Query: 181 ANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQEST 240
ANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQEST
Sbjct: 181 ANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQEST 240
Query: 241 RRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAH 300
RRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAH
Sbjct: 241 RRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAH 300
Query: 301 GPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTL 360
GPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTL
Sbjct: 301 GPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTL 360
Query: 361 LVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNG 420
LVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNG
Sbjct: 361 LVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNG 420
Query: 421 AHSASTLDEATPTLTKDPSRPASDLTAIPQCQLNLLGSLTPG 462
AHSASTLDEATPTLTKDPSRPASDLTAIPQCQLNLLGSLTPG
Sbjct: 421 AHSASTLDEATPTLTKDPSRPASDLTAIPQCQLNLLGSLTPG 462
>gi|5174703 mitogen-activated protein kinase kinase kinase 7
interacting protein 1 isoform alpha [Homo sapiens]
Length = 504
Score = 857 bits (2215), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSEN 60
MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSEN
Sbjct: 1 MAAQRRSLLQSEQQPSWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSEN 60
Query: 61 NCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLES 120
NCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLES
Sbjct: 61 NCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLES 120
Query: 121 IDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYV 180
IDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYV
Sbjct: 121 IDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYV 180
Query: 181 ANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQEST 240
ANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQEST
Sbjct: 181 ANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQEST 240
Query: 241 RRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAH 300
RRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAH
Sbjct: 241 RRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAH 300
Query: 301 GPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTL 360
GPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTL
Sbjct: 301 GPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTL 360
Query: 361 LVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNG 420
LVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNG
Sbjct: 361 LVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNG 420
Query: 421 AHSASTLDEATPTLT 435
AHSASTLDEATPTLT
Sbjct: 421 AHSASTLDEATPTLT 435
>gi|13540531 integrin-linked kinase-associated protein phosphatase
2C [Homo sapiens]
Length = 392
Score = 51.6 bits (122), Expect = 1e-06
Identities = 64/279 (22%), Positives = 113/279 (40%), Gaps = 65/279 (23%)
Query: 65 YGVFNGYDGNRVTNFVAQRLSAELL--LGQLNAEHAEADVRRVLLQAFDVVERSFLESID 122
+ VF+G+ G R + F AQ L L+ + + E V+R LL F + FL+
Sbjct: 148 FAVFDGHGGIRASKFAAQNLHQNLIRKFPKGDVISVEKTVKRCLLDTFKHTDEEFLKQAS 207
Query: 123 DALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVAN 182
SQ P G+ A + ++N LY+AN
Sbjct: 208 ----------SQKPAW------------------------KDGSTATCVLAVDNILYIAN 233
Query: 183 VGTNRALLCKSTVDGLQ--VTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQEST 240
+G +RA+LC+ + + L+ +H +E R+ + G G ++ ++ E +
Sbjct: 234 LGDSRAILCRYNEESQKHAALSLSKEHNPTQYEERMRIQKAG---GNVRDGRVLGVLEVS 290
Query: 241 RRIGDYKVK-YGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAA 299
R IGD + K G T + P+I Q L F++L +GL+K
Sbjct: 291 RSIGDGQYKRCGVTSV--------------PDIRRCQ-LTPNDRFILLACDGLFKVFT-- 333
Query: 300 HGPGQANQEIAAMIDTEFAK----QTSLDAVAQAVVDRV 334
P +A I + ++ E + +++ DA +A +R+
Sbjct: 334 --PEEAVNFILSCLEDEKIQTREGKSAADARYEAACNRL 370
>gi|167466276 protein phosphatase 1K (PP2C domain containing) [Homo
sapiens]
Length = 372
Score = 48.9 bits (115), Expect = 1e-05
Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 20/134 (14%)
Query: 162 ISGGAMAVVAVLLNN-KLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQ 220
++ G A VA+L + +L VA+VG +RA+LC+ + +L +DHT E +DE R+ +
Sbjct: 184 LTSGTTATVALLRDGIELVVASVGDSRAILCRKG----KPMKLTIDHTPERKDEKERIKK 239
Query: 221 LG--LDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPL 278
G + + Q + TR IG D+DL K+ +IAEPE +
Sbjct: 240 CGGFVAWNSLGQPHVNGRLAMTRSIG---------DLDL----KTSGVIAEPETKRIKLH 286
Query: 279 DGVTGFLVLMSEGL 292
FLVL ++G+
Sbjct: 287 HADDSFLVLTTDGI 300
>gi|63003905 protein phosphatase 1 (formerly 2C)-like [Homo sapiens]
Length = 360
Score = 46.2 bits (108), Expect = 6e-05
Identities = 60/262 (22%), Positives = 102/262 (38%), Gaps = 53/262 (20%)
Query: 37 YSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAE 96
YS G+ + ++ + ++G+F+G+ G +V RL L + + +
Sbjct: 96 YSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEAL---KQHLQ 152
Query: 97 HAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLK 156
E D +L ++E+ L SID + EK ++
Sbjct: 153 DYEKDKENSVLSYQTILEQQIL-SIDREMLEKLTVSYD---------------------- 189
Query: 157 TLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELF 216
G ++A+L + L VANVG +R +LC DG L+ DH E
Sbjct: 190 ------EAGTTCLIALLSDKDLTVANVGDSRGVLCDK--DG-NAIPLSHDHKPYQLKERK 240
Query: 217 RLSQLG---LDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIH 273
R+ + G G + GI+ +R +GDY +K L+ P I ++
Sbjct: 241 RIKRAGGFISFNGSWRVQGILA---MSRSLGDYPLKN-------LNVVIPDPDILTFDLD 290
Query: 274 GAQPLDGVTGFLVLMSEGLYKA 295
QP F++L S+GL+ A
Sbjct: 291 KLQP-----EFMILASDGLWDA 307
>gi|10337595 protein phosphatase 1A isoform 1 [Homo sapiens]
Length = 382
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/191 (21%), Positives = 77/191 (40%), Gaps = 28/191 (14%)
Query: 148 YQKILERLKTLEREISG----GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQL 203
+ +I E ++ + + G G+ AV ++ Y N G +R LLC++ +V
Sbjct: 105 FLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNR----KVHFF 160
Query: 204 NVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIG--DYKVKYGYTDIDLLSAA 261
DH N E R+ G G + + +R +G DYK +G + L
Sbjct: 161 TQDHKPSNPLEKERIQNAG---GSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQL--- 214
Query: 262 KSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQT 321
+ EPE+H + + F++L +G++ + N+E+ + +
Sbjct: 215 ----VSPEPEVHDIERSEEDDQFIILACDGIWDVM--------GNEELCDFVRSRLEVTD 262
Query: 322 SLDAVAQAVVD 332
L+ V VVD
Sbjct: 263 DLEKVCNEVVD 273
>gi|29557855 protein phosphatase 1A isoform 2 [Homo sapiens]
Length = 324
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/191 (21%), Positives = 77/191 (40%), Gaps = 28/191 (14%)
Query: 148 YQKILERLKTLEREISG----GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQL 203
+ +I E ++ + + G G+ AV ++ Y N G +R LLC++ +V
Sbjct: 105 FLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNR----KVHFF 160
Query: 204 NVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIG--DYKVKYGYTDIDLLSAA 261
DH N E R+ G G + + +R +G DYK +G + L
Sbjct: 161 TQDHKPSNPLEKERIQNAG---GSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQL--- 214
Query: 262 KSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQT 321
+ EPE+H + + F++L +G++ + N+E+ + +
Sbjct: 215 ----VSPEPEVHDIERSEEDDQFIILACDGIWDVM--------GNEELCDFVRSRLEVTD 262
Query: 322 SLDAVAQAVVD 332
L+ V VVD
Sbjct: 263 DLEKVCNEVVD 273
>gi|193211600 protein phosphatase 1A isoform 3 [Homo sapiens]
Length = 455
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/191 (21%), Positives = 77/191 (40%), Gaps = 28/191 (14%)
Query: 148 YQKILERLKTLEREISG----GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQL 203
+ +I E ++ + + G G+ AV ++ Y N G +R LLC++ +V
Sbjct: 178 FLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNR----KVHFF 233
Query: 204 NVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIG--DYKVKYGYTDIDLLSAA 261
DH N E R+ G G + + +R +G DYK +G + L
Sbjct: 234 TQDHKPSNPLEKERIQNAG---GSVMIQRVNGSLAVSRALGDFDYKCVHGKGPTEQL--- 287
Query: 262 KSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQT 321
+ EPE+H + + F++L +G++ + N+E+ + +
Sbjct: 288 ----VSPEPEVHDIERSEEDDQFIILACDGIWDVM--------GNEELCDFVRSRLEVTD 335
Query: 322 SLDAVAQAVVD 332
L+ V VVD
Sbjct: 336 DLEKVCNEVVD 346
>gi|45439339 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 40.4 bits (93), Expect = 0.003
Identities = 48/160 (30%), Positives = 68/160 (42%), Gaps = 34/160 (21%)
Query: 165 GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG-LQVTQLNVDHTTENEDELFRLSQLGL 223
GA A VA + L+VAN G +RA+L DG L+ DH +NE EL RL L
Sbjct: 271 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLK---L 327
Query: 224 DAGK------IKQVGIICGQESTRRIGDYKVKYG-------------------YTDIDLL 258
+ K +KQ ++ R GD K K+ YT
Sbjct: 328 EHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPP 387
Query: 259 SAAKSKPIIAEPEI--HGAQPLDGVTGFLVLMSEGLYKAL 296
+ + AEPE+ H +P D FLVL ++GL++ +
Sbjct: 388 NYHTPPYLTAEPEVTYHRLRPQD---KFLVLATDGLWETM 424
>gi|239985428 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 3 precursor [Homo sapiens]
Length = 537
Score = 40.4 bits (93), Expect = 0.003
Identities = 48/160 (30%), Positives = 68/160 (42%), Gaps = 34/160 (21%)
Query: 165 GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG-LQVTQLNVDHTTENEDELFRLSQLGL 223
GA A VA + L+VAN G +RA+L DG L+ DH +NE EL RL L
Sbjct: 271 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLK---L 327
Query: 224 DAGK------IKQVGIICGQESTRRIGDYKVKYG-------------------YTDIDLL 258
+ K +KQ ++ R GD K K+ YT
Sbjct: 328 EHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPP 387
Query: 259 SAAKSKPIIAEPEI--HGAQPLDGVTGFLVLMSEGLYKAL 296
+ + AEPE+ H +P D FLVL ++GL++ +
Sbjct: 388 NYHTPPYLTAEPEVTYHRLRPQD---KFLVLATDGLWETM 424
>gi|239985426 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 40.4 bits (93), Expect = 0.003
Identities = 48/160 (30%), Positives = 68/160 (42%), Gaps = 34/160 (21%)
Query: 165 GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG-LQVTQLNVDHTTENEDELFRLSQLGL 223
GA A VA + L+VAN G +RA+L DG L+ DH +NE EL RL L
Sbjct: 296 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLK---L 352
Query: 224 DAGK------IKQVGIICGQESTRRIGDYKVKYG-------------------YTDIDLL 258
+ K +KQ ++ R GD K K+ YT
Sbjct: 353 EHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPP 412
Query: 259 SAAKSKPIIAEPEI--HGAQPLDGVTGFLVLMSEGLYKAL 296
+ + AEPE+ H +P D FLVL ++GL++ +
Sbjct: 413 NYHTPPYLTAEPEVTYHRLRPQD---KFLVLATDGLWETM 449
>gi|239985422 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 2 [Homo sapiens]
Length = 562
Score = 40.4 bits (93), Expect = 0.003
Identities = 48/160 (30%), Positives = 68/160 (42%), Gaps = 34/160 (21%)
Query: 165 GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG-LQVTQLNVDHTTENEDELFRLSQLGL 223
GA A VA + L+VAN G +RA+L DG L+ DH +NE EL RL L
Sbjct: 296 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLK---L 352
Query: 224 DAGK------IKQVGIICGQESTRRIGDYKVKYG-------------------YTDIDLL 258
+ K +KQ ++ R GD K K+ YT
Sbjct: 353 EHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPP 412
Query: 259 SAAKSKPIIAEPEI--HGAQPLDGVTGFLVLMSEGLYKAL 296
+ + AEPE+ H +P D FLVL ++GL++ +
Sbjct: 413 NYHTPPYLTAEPEVTYHRLRPQD---KFLVLATDGLWETM 449
>gi|239985420 pyruvate dehyrogenase phosphatase catalytic subunit 1
isoform 1 [Homo sapiens]
Length = 596
Score = 40.4 bits (93), Expect = 0.003
Identities = 48/160 (30%), Positives = 68/160 (42%), Gaps = 34/160 (21%)
Query: 165 GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDG-LQVTQLNVDHTTENEDELFRLSQLGL 223
GA A VA + L+VAN G +RA+L DG L+ DH +NE EL RL L
Sbjct: 330 GATACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLK---L 386
Query: 224 DAGK------IKQVGIICGQESTRRIGDYKVKYG-------------------YTDIDLL 258
+ K +KQ ++ R GD K K+ YT
Sbjct: 387 EHPKSEAKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPP 446
Query: 259 SAAKSKPIIAEPEI--HGAQPLDGVTGFLVLMSEGLYKAL 296
+ + AEPE+ H +P D FLVL ++GL++ +
Sbjct: 447 NYHTPPYLTAEPEVTYHRLRPQD---KFLVLATDGLWETM 483
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 28/160 (17%)
Query: 165 GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLD 224
G AVVA++ +L VAN G +R ++ ++ + ++ DH E+E EL R+ G
Sbjct: 328 GTTAVVALIRGKQLIVANAGDSRCVVSEAG----KALDMSYDHKPEDEVELARIKNAG-- 381
Query: 225 AGKIKQVG-IICGQESTRRIGDYKVKYGYT---DIDLLSAAKSKPIIAEPEIHGAQPLDG 280
GK+ G + G +R IGD+ K + ++SA ++ + H
Sbjct: 382 -GKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDH------- 433
Query: 281 VTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQ 320
F+V+ +G++ + ++QE+ I ++ +++
Sbjct: 434 --EFMVIACDGIWNVM--------SSQEVVDFIQSKISQR 463
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 28/160 (17%)
Query: 165 GAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLD 224
G AVVA++ +L VAN G +R ++ ++ + ++ DH E+E EL R+ G
Sbjct: 328 GTTAVVALIRGKQLIVANAGDSRCVVSEAG----KALDMSYDHKPEDEVELARIKNAG-- 381
Query: 225 AGKIKQVG-IICGQESTRRIGDYKVKYGYT---DIDLLSAAKSKPIIAEPEIHGAQPLDG 280
GK+ G + G +R IGD+ K + ++SA ++ + H
Sbjct: 382 -GKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDH------- 433
Query: 281 VTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQ 320
F+V+ +G++ + ++QE+ I ++ +++
Sbjct: 434 --EFMVIACDGIWNVM--------SSQEVVDFIQSKISQR 463
>gi|30089948 protein phosphatase 1E [Homo sapiens]
Length = 755
Score = 40.0 bits (92), Expect = 0.004
Identities = 36/138 (26%), Positives = 53/138 (38%), Gaps = 19/138 (13%)
Query: 156 KTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDEL 215
K + G VV + N L+VA VG ++ +L + Q +L H + EDE
Sbjct: 320 KAARESLRCGTTGVVTFIRGNMLHVAWVGDSQVMLVRKG----QAVELMKPHKPDREDEK 375
Query: 216 FRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGA 275
R+ LG G + + R G V D A+ KP I +
Sbjct: 376 QRIEALG---------GCVVWFGAWRVNGSLSVSRAIGD------AEHKPYICGDADSAS 420
Query: 276 QPLDGVTGFLVLMSEGLY 293
LDG +L+L +G Y
Sbjct: 421 TVLDGTEDYLILACDGFY 438
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 39.3 bits (90), Expect = 0.008
Identities = 36/150 (24%), Positives = 55/150 (36%), Gaps = 8/150 (5%)
Query: 302 PGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTF--ASGGERARFCPRHEDMT 359
PG+ + + T A T+ +AV Q D + H A + + P E +
Sbjct: 232 PGKPPSQFVYVFTTHLAN-TAAEAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLP 290
Query: 360 LLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVN 419
L + G P + P P P P A G P P + +S+ S+ S G
Sbjct: 291 LSTPSAGTPQSQ-PPPLPPPPPPAPGSAPPALPPEGPPEDSSQDLAPNSVGAASTGGGTG 349
Query: 420 GAHSASTLDEATPTLTKDPSRPASDLTAIP 449
G H + T T +P P D ++ P
Sbjct: 350 GTHP----NTPTATTANNPLPPGGDPSSAP 375
>gi|122937199 protein phosphatase 1B-like [Homo sapiens]
Length = 430
Score = 38.1 bits (87), Expect = 0.017
Identities = 46/170 (27%), Positives = 75/170 (44%), Gaps = 25/170 (14%)
Query: 136 PEGVPQHQLPPQYQKILERLKTL-EREISGGAMAVVAVLLNNKLYVANVGTNRALLCKST 194
PEGV + L + ERL++L R +GG AVV ++ LY+A+ G +RA+L ++
Sbjct: 133 PEGV-REALRRAFLSADERLRSLWPRVETGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAG 191
Query: 195 VDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTD 254
V DH E R+ G G I++ + +R +GD+ K
Sbjct: 192 A----VAFSTEDHRPLRPRERERIHAAG---GTIRRRRVEGSLAVSRALGDFTYK----- 239
Query: 255 IDLLSAAKSKP-----IIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAA 299
A +P + AEPE+ A F++L S+G++ + A
Sbjct: 240 -----EAPGRPPELQLVSAEPEV-AALARQAEDEFMLLASDGVWDTVSGA 283
>gi|171460934 protein phosphatase 1M isoform b [Homo sapiens]
Length = 247
Score = 38.1 bits (87), Expect = 0.017
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 6/58 (10%)
Query: 164 GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQL 221
GG A+VAV L KLY+AN G +RA+L + ++ L+ + T E E + R+ QL
Sbjct: 2 GGCTALVAVSLQGKLYMANAGDSRAILVRRD----EIRPLSFEFTPETERQ--RIQQL 53
>gi|171460932 protein phosphatase 1M isoform a [Homo sapiens]
Length = 298
Score = 38.1 bits (87), Expect = 0.017
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 6/58 (10%)
Query: 164 GGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQL 221
GG A+VAV L KLY+AN G +RA+L + ++ L+ + T E E + R+ QL
Sbjct: 53 GGCTALVAVSLQGKLYMANAGDSRAILVRRD----EIRPLSFEFTPETERQ--RIQQL 104
>gi|149944715 protein phosphatase 1H (PP2C domain containing) [Homo
sapiens]
Length = 514
Score = 37.0 bits (84), Expect = 0.038
Identities = 21/60 (35%), Positives = 35/60 (58%), Gaps = 9/60 (15%)
Query: 158 LERE-----ISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENE 212
+ERE ISGG A++ + L KLYVAN G +RA++ ++ ++ ++ + T E E
Sbjct: 256 IERERSSYNISGGCTALIVICLLGKLYVANAGDSRAIIIRNG----EIIPMSSEFTPETE 311
>gi|65506328 protein phosphatase 1J (PP2C domain containing) [Homo
sapiens]
Length = 505
Score = 35.8 bits (81), Expect = 0.084
Identities = 20/62 (32%), Positives = 36/62 (58%), Gaps = 6/62 (9%)
Query: 161 EISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQ 220
++ GG A+V + L K+YVAN G +RA++ ++ ++ ++ + T E E + RL
Sbjct: 255 QVEGGCCALVVIYLLGKVYVANAGDSRAIIVRNG----EIIPMSREFTPETERQ--RLQL 308
Query: 221 LG 222
LG
Sbjct: 309 LG 310
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 33.5 bits (75), Expect = 0.42
Identities = 34/166 (20%), Positives = 65/166 (39%), Gaps = 8/166 (4%)
Query: 286 VLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASG 345
+L ++ +A A QA + A + Q A AQA + + A
Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 235
Query: 346 GERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSV 405
+A+ + + +G + T SPAPA + +++ +T+ TSV
Sbjct: 236 QAQAQ---AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292
Query: 406 TLSLVMPSQGQMVNGAHSASTLDEATPTLT-KDPSRPASDLTAIPQ 450
++ P+ +S + ATPT++ P+ A+ + +PQ
Sbjct: 293 AQTVSTPTTQDQT----PSSAVSVATPTVSVSTPAPTATPVQTVPQ 334
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 33.5 bits (75), Expect = 0.42
Identities = 34/166 (20%), Positives = 65/166 (39%), Gaps = 8/166 (4%)
Query: 286 VLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASG 345
+L ++ +A A QA + A + Q A AQA + + A
Sbjct: 176 MLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 235
Query: 346 GERARFCPRHEDMTLLVRNFGYPLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSV 405
+A+ + + +G + T SPAPA + +++ +T+ TSV
Sbjct: 236 QAQAQ---AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSV 292
Query: 406 TLSLVMPSQGQMVNGAHSASTLDEATPTLT-KDPSRPASDLTAIPQ 450
++ P+ +S + ATPT++ P+ A+ + +PQ
Sbjct: 293 AQTVSTPTTQDQT----PSSAVSVATPTVSVSTPAPTATPVQTVPQ 334
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 32.7 bits (73), Expect = 0.71
Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 15/105 (14%)
Query: 368 PLGEMSQPTPSPAPAAGGRVYPVS-----------VPYSSAQSTSKTSVTLSLVMPSQGQ 416
P+ ++ + SP PA G + P+S VP S+ TS TLS
Sbjct: 3076 PVVTSTEVSSSPTPAEGTSM-PISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTST 3134
Query: 417 MVNG---AHSASTLDEATPTLTKDPSRPASDLTAIPQCQLNLLGS 458
V AHS+ T E T T PS ++ LT +P + ++ S
Sbjct: 3135 PVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSS 3179
Score = 29.3 bits (64), Expect = 7.9
Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 14/91 (15%)
Query: 373 SQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMV-------------- 418
S SP P A G P S P + ++ V+ ++V S+ +
Sbjct: 1017 STEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTY 1076
Query: 419 NGAHSASTLDEATPTLTKDPSRPASDLTAIP 449
+ A S+ST + T T S ++ LT++P
Sbjct: 1077 SQASSSSTTADGTSMPTSTYSEGSTPLTSVP 1107
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 32.3 bits (72), Expect = 0.93
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 11/82 (13%)
Query: 368 PLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTL 427
P+G + P P P P+A P AQ T T T S +P + +A+
Sbjct: 1672 PMGSPASPQPHPLPSA---------PPRPAQHT--TMATRSPALPPETPAAASLSTATDG 1720
Query: 428 DEATPTLTKDPSRPASDLTAIP 449
ATP ++ + +RP+ L+ +P
Sbjct: 1721 LAATPFMSLESTRPSQLLSGLP 1742
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 32.3 bits (72), Expect = 0.93
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 11/82 (13%)
Query: 368 PLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTL 427
P+G + P P P P+A P AQ T T T S +P + +A+
Sbjct: 1744 PMGSPASPQPHPLPSA---------PPRPAQHT--TMATRSPALPPETPAAASLSTATDG 1792
Query: 428 DEATPTLTKDPSRPASDLTAIP 449
ATP ++ + +RP+ L+ +P
Sbjct: 1793 LAATPFMSLESTRPSQLLSGLP 1814
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 32.3 bits (72), Expect = 0.93
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 11/82 (13%)
Query: 368 PLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTL 427
P+G + P P P P+A P AQ T T T S +P + +A+
Sbjct: 1672 PMGSPASPQPHPLPSA---------PPRPAQHT--TMATRSPALPPETPAAASLSTATDG 1720
Query: 428 DEATPTLTKDPSRPASDLTAIP 449
ATP ++ + +RP+ L+ +P
Sbjct: 1721 LAATPFMSLESTRPSQLLSGLP 1742
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 32.3 bits (72), Expect = 0.93
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 11/82 (13%)
Query: 368 PLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTL 427
P+G + P P P P+A P AQ T T T S +P + +A+
Sbjct: 1744 PMGSPASPQPHPLPSA---------PPRPAQHT--TMATRSPALPPETPAAASLSTATDG 1792
Query: 428 DEATPTLTKDPSRPASDLTAIP 449
ATP ++ + +RP+ L+ +P
Sbjct: 1793 LAATPFMSLESTRPSQLLSGLP 1814
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 32.3 bits (72), Expect = 0.93
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 11/82 (13%)
Query: 368 PLGEMSQPTPSPAPAAGGRVYPVSVPYSSAQSTSKTSVTLSLVMPSQGQMVNGAHSASTL 427
P+G + P P P P+A P AQ T T T S +P + +A+
Sbjct: 1672 PMGSPASPQPHPLPSA---------PPRPAQHT--TMATRSPALPPETPAAASLSTATDG 1720
Query: 428 DEATPTLTKDPSRPASDLTAIP 449
ATP ++ + +RP+ L+ +P
Sbjct: 1721 LAATPFMSLESTRPSQLLSGLP 1742
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,163,193
Number of Sequences: 37866
Number of extensions: 757581
Number of successful extensions: 2441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 2380
Number of HSP's gapped (non-prelim): 107
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.