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Search of human proteins with 41281447
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41281447 intraflagellar transport 140 [Homo sapiens]
(1462 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41281447 intraflagellar transport 140 [Homo sapiens] 2942 0.0
gi|55743151 WD repeat domain 19 [Homo sapiens] 57 1e-07
gi|22749275 CDC20 cell division cycle 20 homolog B isoform 1 [Ho... 51 7e-06
gi|46358428 selective LIM binding factor homolog [Homo sapiens] 49 3e-05
gi|224593764 CDC20 cell division cycle 20 homolog B isoform 2 [H... 46 2e-04
gi|56790932 echinoderm microtubule associated protein like 1 iso... 43 0.003
gi|56790930 echinoderm microtubule associated protein like 1 iso... 43 0.003
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 41 0.010
gi|118402582 cell division cycle 20 [Homo sapiens] 40 0.013
gi|6912356 echinoderm microtubule associated protein like 2 [Hom... 40 0.016
gi|142976686 nuclear autoantigen isoform 1 [Homo sapiens] 40 0.022
gi|142976675 nuclear autoantigen isoform 2 [Homo sapiens] 40 0.022
gi|4757988 WD repeat domain 39 [Homo sapiens] 39 0.048
gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens] 39 0.048
gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens] 39 0.048
gi|12962937 achalasia, adrenocortical insufficiency, alacrimia (... 37 0.14
gi|22907052 actin related protein 2/3 complex subunit 1A [Homo s... 37 0.18
gi|148727341 serine/threonine kinase receptor associated protein... 37 0.18
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 36 0.24
gi|89886480 zinedin isoform 2 [Homo sapiens] 36 0.24
gi|89886477 zinedin isoform 1 [Homo sapiens] 36 0.24
gi|110227615 echinoderm microtubule associated protein like 3 [H... 36 0.31
gi|19913369 transducin beta-like 3 [Homo sapiens] 36 0.31
gi|21536371 telomerase-associated protein 1 [Homo sapiens] 35 0.41
gi|120587023 down-regulated in metastasis [Homo sapiens] 35 0.41
gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name... 35 0.41
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 35 0.41
gi|19913367 transducin beta-like 1Y [Homo sapiens] 35 0.41
gi|19913365 transducin beta-like 1Y [Homo sapiens] 35 0.41
gi|15150805 transducin beta-like 1Y [Homo sapiens] 35 0.41
>gi|41281447 intraflagellar transport 140 [Homo sapiens]
Length = 1462
Score = 2942 bits (7626), Expect = 0.0
Identities = 1462/1462 (100%), Positives = 1462/1462 (100%)
Query: 1 MALYYDHQIEAPDAAGSPSFISWHPVHPFLAVAYISTTSTGSVDIYLEQGECVPDTHVER 60
MALYYDHQIEAPDAAGSPSFISWHPVHPFLAVAYISTTSTGSVDIYLEQGECVPDTHVER
Sbjct: 1 MALYYDHQIEAPDAAGSPSFISWHPVHPFLAVAYISTTSTGSVDIYLEQGECVPDTHVER 60
Query: 61 PFRVASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLS 120
PFRVASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLS
Sbjct: 61 PFRVASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLS 120
Query: 121 GDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPPPGEDLVQLAKAAVSGDEKA 180
GDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPPPGEDLVQLAKAAVSGDEKA
Sbjct: 121 GDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPPPGEDLVQLAKAAVSGDEKA 180
Query: 181 LDMFNWKKSSSGSLLKMGSHEGLLFFVSLMDGTVHYVDEKGKTTQVVSADSTIQMLFYME 240
LDMFNWKKSSSGSLLKMGSHEGLLFFVSLMDGTVHYVDEKGKTTQVVSADSTIQMLFYME
Sbjct: 181 LDMFNWKKSSSGSLLKMGSHEGLLFFVSLMDGTVHYVDEKGKTTQVVSADSTIQMLFYME 240
Query: 241 KREALVVVTENLRLSLYTVPPEGKAEEVMKVKLSGKTGRRADIALIEGSLLVMAVGEAAL 300
KREALVVVTENLRLSLYTVPPEGKAEEVMKVKLSGKTGRRADIALIEGSLLVMAVGEAAL
Sbjct: 241 KREALVVVTENLRLSLYTVPPEGKAEEVMKVKLSGKTGRRADIALIEGSLLVMAVGEAAL 300
Query: 301 RFWDIERGENYILSPDEKFGFEKGENMNCVCYCKVKGLLAAGTDRGRVAMWRKVPDFLGS 360
RFWDIERGENYILSPDEKFGFEKGENMNCVCYCKVKGLLAAGTDRGRVAMWRKVPDFLGS
Sbjct: 301 RFWDIERGENYILSPDEKFGFEKGENMNCVCYCKVKGLLAAGTDRGRVAMWRKVPDFLGS 360
Query: 361 PGAEGKDRWALQTPTELQGNITQIQWGSRKNLLAVNSVISVAILSERAMSSHFHQQVAAM 420
PGAEGKDRWALQTPTELQGNITQIQWGSRKNLLAVNSVISVAILSERAMSSHFHQQVAAM
Sbjct: 361 PGAEGKDRWALQTPTELQGNITQIQWGSRKNLLAVNSVISVAILSERAMSSHFHQQVAAM 420
Query: 421 QVSPSLLNVCFLSTGVAHSLRTDMHISGVFATKDAVAVWNGRQVAIFELSGAAIRSAGTF 480
QVSPSLLNVCFLSTGVAHSLRTDMHISGVFATKDAVAVWNGRQVAIFELSGAAIRSAGTF
Sbjct: 421 QVSPSLLNVCFLSTGVAHSLRTDMHISGVFATKDAVAVWNGRQVAIFELSGAAIRSAGTF 480
Query: 481 LCETPVLAMHEENVYTVESNRVQVRTWQGTVKQLLLFSETEGNPCFLDICGNFLVVGTDL 540
LCETPVLAMHEENVYTVESNRVQVRTWQGTVKQLLLFSETEGNPCFLDICGNFLVVGTDL
Sbjct: 481 LCETPVLAMHEENVYTVESNRVQVRTWQGTVKQLLLFSETEGNPCFLDICGNFLVVGTDL 540
Query: 541 AHFKSFDLSRREAKAHCSCRSLAELVPGVGGIASLRCSSSGSTISILPSKADNSPDSKIC 600
AHFKSFDLSRREAKAHCSCRSLAELVPGVGGIASLRCSSSGSTISILPSKADNSPDSKIC
Sbjct: 541 AHFKSFDLSRREAKAHCSCRSLAELVPGVGGIASLRCSSSGSTISILPSKADNSPDSKIC 600
Query: 601 FYDVEMDTVTVFDFKTGQIDRRETLSFNEQETNKSHLFVDEGLKNYVPVNHFWDQSEPRL 660
FYDVEMDTVTVFDFKTGQIDRRETLSFNEQETNKSHLFVDEGLKNYVPVNHFWDQSEPRL
Sbjct: 601 FYDVEMDTVTVFDFKTGQIDRRETLSFNEQETNKSHLFVDEGLKNYVPVNHFWDQSEPRL 660
Query: 661 FVCEAVQETPRSQPQSANGQPQDGRAGPAADVLILSFFISEEHGFLLHESFPRPATSHSL 720
FVCEAVQETPRSQPQSANGQPQDGRAGPAADVLILSFFISEEHGFLLHESFPRPATSHSL
Sbjct: 661 FVCEAVQETPRSQPQSANGQPQDGRAGPAADVLILSFFISEEHGFLLHESFPRPATSHSL 720
Query: 721 LGMEVPYYYFTRKPEEADREDEVEPGCHHIPQMVSRRPLRDFVGLEDCDKATRDAMLHFS 780
LGMEVPYYYFTRKPEEADREDEVEPGCHHIPQMVSRRPLRDFVGLEDCDKATRDAMLHFS
Sbjct: 721 LGMEVPYYYFTRKPEEADREDEVEPGCHHIPQMVSRRPLRDFVGLEDCDKATRDAMLHFS 780
Query: 781 FFVTIGDMDEAFKSIKLIKSEAVWENMARMCVKTQRLDVAKVCLGNMGHARGARALREAE 840
FFVTIGDMDEAFKSIKLIKSEAVWENMARMCVKTQRLDVAKVCLGNMGHARGARALREAE
Sbjct: 781 FFVTIGDMDEAFKSIKLIKSEAVWENMARMCVKTQRLDVAKVCLGNMGHARGARALREAE 840
Query: 841 QEPELEARVAVLATQLGMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHL 900
QEPELEARVAVLATQLGMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHL
Sbjct: 841 QEPELEARVAVLATQLGMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHL 900
Query: 901 RSTYHRYAGHLEASADCSRALSYYEKSDTHRFEVPRMLSEDLPSLELYVNKMKDKTLWRW 960
RSTYHRYAGHLEASADCSRALSYYEKSDTHRFEVPRMLSEDLPSLELYVNKMKDKTLWRW
Sbjct: 901 RSTYHRYAGHLEASADCSRALSYYEKSDTHRFEVPRMLSEDLPSLELYVNKMKDKTLWRW 960
Query: 961 WAQYLESQGEMDAALHYYELARDHFSLVRIHCFQGNVQKAAQIANETGNLAASYHLARQY 1020
WAQYLESQGEMDAALHYYELARDHFSLVRIHCFQGNVQKAAQIANETGNLAASYHLARQY
Sbjct: 961 WAQYLESQGEMDAALHYYELARDHFSLVRIHCFQGNVQKAAQIANETGNLAASYHLARQY 1020
Query: 1021 ESQEEVGQAVHFYTRAQAFKNAIRLCKENGLDDQLMNLALLSSPEDMIEAARYYEEKGVQ 1080
ESQEEVGQAVHFYTRAQAFKNAIRLCKENGLDDQLMNLALLSSPEDMIEAARYYEEKGVQ
Sbjct: 1021 ESQEEVGQAVHFYTRAQAFKNAIRLCKENGLDDQLMNLALLSSPEDMIEAARYYEEKGVQ 1080
Query: 1081 MDRAVMLYHKAGHFSKALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIEHSQYE 1140
MDRAVMLYHKAGHFSKALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIEHSQYE
Sbjct: 1081 MDRAVMLYHKAGHFSKALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIEHSQYE 1140
Query: 1141 RAVELLLAARKYQEALQLCLGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQIADCCM 1200
RAVELLLAARKYQEALQLCLGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQIADCCM
Sbjct: 1141 RAVELLLAARKYQEALQLCLGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQIADCCM 1200
Query: 1201 RQGSYHLATKKYTQAGNKLKAMRALLKSGDTEKITFFASVSRQKEIYIMAANYLQSLDWR 1260
RQGSYHLATKKYTQAGNKLKAMRALLKSGDTEKITFFASVSRQKEIYIMAANYLQSLDWR
Sbjct: 1201 RQGSYHLATKKYTQAGNKLKAMRALLKSGDTEKITFFASVSRQKEIYIMAANYLQSLDWR 1260
Query: 1261 KEPEIMKNIIGFYTKGRALDLLAGFYDACAQVEIDEYQNYDKAHGALTEAYKCLAKAKAK 1320
KEPEIMKNIIGFYTKGRALDLLAGFYDACAQVEIDEYQNYDKAHGALTEAYKCLAKAKAK
Sbjct: 1261 KEPEIMKNIIGFYTKGRALDLLAGFYDACAQVEIDEYQNYDKAHGALTEAYKCLAKAKAK 1320
Query: 1321 SPLDQETRLAQLQSRMALVKRFIQARRTYTEDPKESIKQCELLLEEPDLDSTIRIGDVYG 1380
SPLDQETRLAQLQSRMALVKRFIQARRTYTEDPKESIKQCELLLEEPDLDSTIRIGDVYG
Sbjct: 1321 SPLDQETRLAQLQSRMALVKRFIQARRTYTEDPKESIKQCELLLEEPDLDSTIRIGDVYG 1380
Query: 1381 FLVEHYVRKEEYQTAYRFLEEMRRRLPLANMSYYVSPQAVDAVHRGLGLPLPRTVPEQVR 1440
FLVEHYVRKEEYQTAYRFLEEMRRRLPLANMSYYVSPQAVDAVHRGLGLPLPRTVPEQVR
Sbjct: 1381 FLVEHYVRKEEYQTAYRFLEEMRRRLPLANMSYYVSPQAVDAVHRGLGLPLPRTVPEQVR 1440
Query: 1441 HNSMEDARELDEEVVEEADDDP 1462
HNSMEDARELDEEVVEEADDDP
Sbjct: 1441 HNSMEDARELDEEVVEEADDDP 1462
>gi|55743151 WD repeat domain 19 [Homo sapiens]
Length = 1342
Score = 57.0 bits (136), Expect = 1e-07
Identities = 111/564 (19%), Positives = 191/564 (33%), Gaps = 90/564 (15%)
Query: 790 EAFKSIKLIKSEAVWENMARMCVKTQRLDVAKVC---LGNMGHARGARALREAEQEPELE 846
+A++ +++ EA W +AR C+ ++ A +GN+G ++ E L
Sbjct: 664 DAWEMCRILNDEAAWNELARACLHHMEVEFAIRVYRRIGNVGIVMSLEQIKGIEDYNLLA 723
Query: 847 ARVAVLATQLGMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHLRSTYHR 906
+A+ + +D LY + + W ALQ+A+H +
Sbjct: 724 GHLAMFTNDYNLAQD---LYLASSCPIAALEMRRDLQHWDSALQLAKHLAPDQIPFISKE 780
Query: 907 YAGHLEASADCSRALSYYEKS--------DTHRFEVPRMLSEDLPSLELYVN---KMKDK 955
YA LE + D AL++YEK D +S + + VN K +
Sbjct: 781 YAIQLEFAGDYVNALAHYEKGITGDNKEHDEACLAGVAQMSIRMGDIRRGVNQALKHPSR 840
Query: 956 TLWRWWAQYLESQGEMDAALHYYELARDHFSLVRIHCFQGNVQKAAQIANETGNLAASYH 1015
L R LE+ + A YE + ++ N K + +
Sbjct: 841 VLKRDCGAILENMKQFSEAAQLYEKGLYYDKAASVYIRSKNWAKVGDLLPHVSSPKIHLQ 900
Query: 1016 LARQYESQEEVGQAVHFYTRAQAFKNAIRLCKENGLDDQLMNLALLSSPEDMIEAARYYE 1075
A+ E+ +AV Y A+ +++ IR+ ++ L++PE
Sbjct: 901 YAKAKEADGRYKEAVVAYENAKQWQSVIRIYLDH-----------LNNPE---------- 939
Query: 1076 EKGVQMDRAVMLYHKAGHFSKALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIE 1135
KA+ + TQ +++A FF++
Sbjct: 940 --------------------KAVNIVRETQSLDGAKMVAR----------------FFLQ 963
Query: 1136 HSQYERAVELLLAARKYQEALQLCLGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQI 1195
Y A++ L+ ++ EA L N KM + D E++ E + I
Sbjct: 964 LGDYGSAIQFLVMSKCNNEAFTLAQQHN---------KMEIYADIIG-SEDTTNEDYQSI 1013
Query: 1196 ADCCMRQGSYHLATKKYTQAGNKLKAMRALLK---SGDTEKITFFASVSRQKEIYIMAAN 1252
A + Y A K + G +A++ LK S D I Q + ++
Sbjct: 1014 ALYFEGEKRYLQAGKFFLLCGQYSRALKHFLKCPSSEDNVAIEMAIETVGQAKDELLTNQ 1073
Query: 1253 YLQSLDWRKE--PEIMKNIIGFYTKGRALDLLAGFYDACAQVEIDEYQNYDKAHGALTEA 1310
+ L + P+ K + Y + A A+ E NY AH L
Sbjct: 1074 LIDHLLGENDGMPKDAKYLFRLYMALKQYREAAQTAIIIAREE-QSAGNYRNAHDVLFSM 1132
Query: 1311 YKCLAKAKAKSPLDQETRLAQLQS 1334
Y L K K P + T L L S
Sbjct: 1133 YAELKSQKIKIPSEMATNLMILHS 1156
>gi|22749275 CDC20 cell division cycle 20 homolog B isoform 1 [Homo
sapiens]
Length = 515
Score = 51.2 bits (121), Expect = 7e-06
Identities = 59/225 (26%), Positives = 87/225 (38%), Gaps = 52/225 (23%)
Query: 64 VASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDR 123
V +L W+ +L+ G G V + + + H L H + L+WSP G L SG
Sbjct: 318 VGALSWN--HFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCS 375
Query: 124 LGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPPPGEDLVQLAKAAVSGDEKALDM 183
G+L +W D QG PL K +T S KA+D
Sbjct: 376 DGLLTIWPHDPGASAQGQPL------KVITQ--------------------STAVKAMDW 409
Query: 184 FNWKKSSSGSLLKMGSHEGLLFFVSLMDGTVHYVD-EKGKTTQVVSADSTIQMLFYMEKR 242
W+ SG L G + DG +H +D GK+ Q S +S I L ++ K
Sbjct: 410 CPWQ---SGVLAIGG---------GMKDGRLHILDINAGKSIQTPSTNSQICSLIWLPKT 457
Query: 243 EALVV--VTENLRLSLYTVPPEGKAEEVMKVKLSGKTGRRADIAL 285
+ + T ++++T P V SG GR +AL
Sbjct: 458 KEIATGQGTPKNDVTVWTCP---------TVSRSGHRGRVLHLAL 493
>gi|46358428 selective LIM binding factor homolog [Homo sapiens]
Length = 1749
Score = 49.3 bits (116), Expect = 3e-05
Identities = 85/391 (21%), Positives = 148/391 (37%), Gaps = 97/391 (24%)
Query: 799 KSEAVWENMARMCVKTQRLDVAKVCLGNMGHARGARALREAEQEPELEAR--------VA 850
++EA+W+ ++++ ++ ++L +A+ C +G AR L E + + +R
Sbjct: 623 ETEAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQVSREYGGEGTDFY 682
Query: 851 VLATQLGMLED----AEQLYRKCKRHDLLNKFYQAAGRWQEALQVAE---HHDRVHLRST 903
+ +L MLE AE ++ + + YQ RW E + VAE H LR +
Sbjct: 683 QVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPALEKLRRS 742
Query: 904 YHRY---------AGHL-EASADCSRALSYYEKSDTHRFEVPRMLSEDLPSLELYVNKMK 953
Y+++ AG L E+ D A+S Y K+ +L+ + EL N
Sbjct: 743 YYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTRE----ELLAN--- 795
Query: 954 DKTLWRWWAQYLESQGEMDAAL---HYYELARDHFSLVRIHCFQGNVQKAAQIANETGNL 1010
E + AAL YE A D F +IH N QKA +
Sbjct: 796 -----------TELVEHITAALIKGELYERAGDLFE--KIH----NPQKALEC------- 831
Query: 1011 AASYHLARQYESQEEVGQAVHFYTRAQAFKNAIRLCKENGLDDQLMNLALLSSPEDMIEA 1070
Y + AF A+ LA L+ P ++++
Sbjct: 832 ----------------------YRKGNAFMKAV-------------ELARLAFPVEVVKL 856
Query: 1071 ARYYEEKGV---QMDRAVMLYHKAGHFSKALELAFATQQFVALQLIAEDLDETSDPALLA 1127
+ + V Q+D A+ Y +A KA+E A +Q+ I + D +
Sbjct: 857 EEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKYYP 916
Query: 1128 RCSDFFIEHSQYERAVELLLAARKYQEALQL 1158
+ + +YE A EL + ++A+ +
Sbjct: 917 LVAQHYASLQEYEIAEELYTKGDRTKDAIDM 947
Score = 47.0 bits (110), Expect = 1e-04
Identities = 66/355 (18%), Positives = 136/355 (38%), Gaps = 13/355 (3%)
Query: 882 AGRWQEALQVAEHHDRVHLRSTYHRYAGHLEASADCSRALSYYEKSDTHRFEVPRMLS-- 939
A +W++A+ + + DR Y A H + + A Y K D + +
Sbjct: 893 ARQWKKAIYILDLQDRNTASKYYPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAG 952
Query: 940 --EDLPSLELYVNKMKD-KTLWRWWAQYLESQGEMDAALHYYELARDH---FSLVRIHCF 993
E L + + +D L+ AQ +E QG+ A Y ++ ++ + H
Sbjct: 953 RWEQAHKLAMKCMRPEDVSVLYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKL 1012
Query: 994 QGNVQKAAQIANETGNLAASYHLARQYESQEEVGQAVHFYTRAQAFKNAIRLCKENGLDD 1053
++ + + HL ++ E++ + +A + Y AQ +K + + + +GL +
Sbjct: 1013 YDDMIRLVGKHHPDLLSDTHLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWE 1072
Query: 1054 QLMNLALLSSPEDMIEAARYYEEKGVQMDRAVMLYHKAGHFSKALELAFATQQFVALQLI 1113
+ +A + + Y K + + AV L +K G A++ A F +
Sbjct: 1073 EAYRVARTQGGANAHKHVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFEL 1132
Query: 1114 AEDLDETSDPALLARCSDFFIEHSQYERA-VELLLAARKYQEALQLCLGQNMSITEEMAE 1172
+ + P + + + F + ++E A E + A + + L Q+ + +AE
Sbjct: 1133 SRLALKHKTPEVHLKYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAE 1192
Query: 1173 KMTVAKDSSDLPEESRREL----LEQIADCCMRQGSYHLATKKYTQAGNKLKAMR 1223
+ L ++R L ++ +R LA Y +AG A+R
Sbjct: 1193 AHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALR 1247
Score = 40.0 bits (92), Expect = 0.016
Identities = 57/266 (21%), Positives = 102/266 (38%), Gaps = 39/266 (14%)
Query: 857 GMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHLRSTYHRYAGHL----- 911
G L++AE Y + + Y+A+G W+EA +VA R + H++ +L
Sbjct: 1043 GRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVA----RTQGGANAHKHVAYLWAKSL 1098
Query: 912 --EASADCSRALSYYEKSDTHRFEVPRMLSEDLPSLELYVNKMKDKTLWRWWAQYLESQG 969
EA+ L E + H + E L K K + +A +LE +G
Sbjct: 1099 GGEAAVRLLNKLGLLEAAVDHAAD--NCSFEFAFELSRLALKHKTPEVHLKYAMFLEDEG 1156
Query: 970 EMDAALHYYELARDHFSLVRIHCFQGNVQKAAQIANETGNLAASYHLARQYES------- 1022
+ + A + A V + + + A ++A + + L Q
Sbjct: 1157 KFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDF 1216
Query: 1023 ---------QEEVGQAVHFYTRAQAFKNAIRLCKE------NGLDDQLMNLALLSSP--- 1064
+ G A+++Y A + +A+R+CK+ L ++ A
Sbjct: 1217 QKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQEEYEREATKKGARGV 1276
Query: 1065 EDMIEAARYYEEKGVQMDRAVMLYHK 1090
E +E AR++E+ G + RAV Y K
Sbjct: 1277 EGFVEQARHWEQAG-EYSRAVDCYLK 1301
Score = 35.4 bits (80), Expect = 0.41
Identities = 77/381 (20%), Positives = 142/381 (37%), Gaps = 66/381 (17%)
Query: 857 GMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHLRSTYHRYAGHLEASAD 916
G +AE+LY + DL Y+ + + +++ H L T+ LEA
Sbjct: 985 GKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSDTHLHLGKELEAEGR 1044
Query: 917 CSRALSYYEKSDTHRFEVPRMLSEDLPSLELYVNKMKDKTLWRWWAQYLESQGEMDAALH 976
A Y+ YLE+Q E A ++
Sbjct: 1045 LQEA-EYH---------------------------------------YLEAQ-EWKATVN 1063
Query: 977 YYELARDHFSLVRIHCFQGNVQKAAQIANETGNLAASYHLARQYESQEEVGQAVHFYTRA 1036
Y + G ++A ++A G A H+A + AV +
Sbjct: 1064 MYRAS-------------GLWEEAYRVARTQGGANAHKHVAYLWAKSLGGEAAVRLLNKL 1110
Query: 1037 QAFKNAIRLCKENGLDD---QLMNLALL-SSPEDMIEAARYYEEKGVQMDRAVMLYHKAG 1092
+ A+ +N + +L LAL +PE ++ A + E++G + + A + +AG
Sbjct: 1111 GLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHLKYAMFLEDEG-KFEEAEAEFIRAG 1169
Query: 1093 HFSKALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIEHSQYERAVELLLAARKY 1152
+A+ + Q + A Q +AE D S +L + +E +++A LLL A++
Sbjct: 1170 KPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLVGQARGALEEKDFQKAEGLLLRAQRP 1229
Query: 1153 QEALQLCLGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQIADCCMRQG--SYHLATK 1210
AL + ++ + + KD E+ +E E+ A +G + +
Sbjct: 1230 GLALNYYKEAGL-----WSDALRICKDYVPSQLEALQEEYEREATKKGARGVEGFVEQAR 1284
Query: 1211 KYTQAGNKLKAMRALLKSGDT 1231
+ QAG +A+ LK D+
Sbjct: 1285 HWEQAGEYSRAVDCYLKVRDS 1305
>gi|224593764 CDC20 cell division cycle 20 homolog B isoform 2 [Homo
sapiens]
Length = 477
Score = 46.2 bits (108), Expect = 2e-04
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 64 VASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDR 123
V +L W+ +L+ G G V + + + H L H + L+WSP G L SG
Sbjct: 318 VGALSWN--HFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCS 375
Query: 124 LGVLLLWRLDQRGRVQGTPL 143
G+L +W D QG PL
Sbjct: 376 DGLLTIWPHDPGASAQGQPL 395
>gi|56790932 echinoderm microtubule associated protein like 1
isoform a [Homo sapiens]
Length = 834
Score = 42.7 bits (99), Expect = 0.003
Identities = 22/69 (31%), Positives = 37/69 (53%)
Query: 69 WHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLL 128
+HP+ V+AVG TG VF+ + K+ T+ ++V+R+SP GN L G +
Sbjct: 611 FHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIY 670
Query: 129 LWRLDQRGR 137
++ + GR
Sbjct: 671 IYGVSDNGR 679
>gi|56790930 echinoderm microtubule associated protein like 1
isoform b [Homo sapiens]
Length = 815
Score = 42.7 bits (99), Expect = 0.003
Identities = 22/69 (31%), Positives = 37/69 (53%)
Query: 69 WHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLL 128
+HP+ V+AVG TG VF+ + K+ T+ ++V+R+SP GN L G +
Sbjct: 592 FHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIY 651
Query: 129 LWRLDQRGR 137
++ + GR
Sbjct: 652 IYGVSDNGR 660
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 40.8 bits (94), Expect = 0.010
Identities = 23/67 (34%), Positives = 34/67 (50%)
Query: 64 VASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDR 123
V LC P L LAVG+E G + +F+ E + H A IT L++ G L SG +
Sbjct: 68 VTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSK 127
Query: 124 LGVLLLW 130
+++W
Sbjct: 128 DTDIIVW 134
>gi|118402582 cell division cycle 20 [Homo sapiens]
Length = 499
Score = 40.4 bits (93), Expect = 0.013
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 7/113 (6%)
Query: 19 SFISWHPVHPFLAVAYISTTSTGSVDIYLEQGECVPDTHVERPFRVASLCWHPTRLVLAV 78
S ++W +LAV TS+ V ++ Q + RV SL W+ +L+
Sbjct: 230 SSVAWIKEGNYLAVG----TSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNS--YILSS 283
Query: 79 GWETGEVTVFNKQDKEQHTMPLT-HTADITVLRWSPSGNCLLSGDRLGVLLLW 130
G +G + + + E H L+ H+ ++ LRW+P G L SG ++ +W
Sbjct: 284 GSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVW 336
>gi|6912356 echinoderm microtubule associated protein like 2 [Homo
sapiens]
Length = 649
Score = 40.0 bits (92), Expect = 0.016
Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
Query: 58 VERPFRVASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHT---ADITVLRWSPS 114
+E P R A +HP+ VLAVG TG + D E H + HT I+V+ +SP
Sbjct: 417 IEDPARSAG--FHPSGSVLAVGTVTGRWLLL---DTETHDLVAIHTDGNEQISVVSFSPD 471
Query: 115 GNCLLSGDRLGVLLLWRLDQRGR 137
G L G ++ ++ +DQ GR
Sbjct: 472 GAYLAVGSHDNLVYVYTVDQGGR 494
>gi|142976686 nuclear autoantigen isoform 1 [Homo sapiens]
Length = 797
Score = 39.7 bits (91), Expect = 0.022
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 15/131 (11%)
Query: 17 SPSFISWHPVHPFLAVAYISTTSTGSVDIY-LEQGECVP------DTHVERPFRVASLCW 69
S FI P H +++ +TGS IY LE + + D+ ++ + +
Sbjct: 636 SVDFIGCDPAH------MVTSFNTGSAVIYDLETSQSLVILSSQVDSGLQSNNHINRVVS 689
Query: 70 HPTRLVLAVGWETGEVTVF-NKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLL 128
HPT V E + F NK K H+M + H +T L P+G L+SG +
Sbjct: 690 HPTLPVTITAHEDRHIKFFDNKTGKMIHSM-VAHLDAVTSLAVDPNGIYLMSGSHDCSIR 748
Query: 129 LWRLDQRGRVQ 139
LW LD + VQ
Sbjct: 749 LWNLDSKTCVQ 759
>gi|142976675 nuclear autoantigen isoform 2 [Homo sapiens]
Length = 713
Score = 39.7 bits (91), Expect = 0.022
Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 15/131 (11%)
Query: 17 SPSFISWHPVHPFLAVAYISTTSTGSVDIY-LEQGECVP------DTHVERPFRVASLCW 69
S FI P H +++ +TGS IY LE + + D+ ++ + +
Sbjct: 552 SVDFIGCDPAH------MVTSFNTGSAVIYDLETSQSLVILSSQVDSGLQSNNHINRVVS 605
Query: 70 HPTRLVLAVGWETGEVTVF-NKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLL 128
HPT V E + F NK K H+M + H +T L P+G L+SG +
Sbjct: 606 HPTLPVTITAHEDRHIKFFDNKTGKMIHSM-VAHLDAVTSLAVDPNGIYLMSGSHDCSIR 664
Query: 129 LWRLDQRGRVQ 139
LW LD + VQ
Sbjct: 665 LWNLDSKTCVQ 675
>gi|4757988 WD repeat domain 39 [Homo sapiens]
Length = 339
Score = 38.5 bits (88), Expect = 0.048
Identities = 73/345 (21%), Positives = 136/345 (39%), Gaps = 45/345 (13%)
Query: 20 FISWHPVHPFLAVAYISTTSTGSVDIYLEQGE---CVPDTHVERPFRVASLCWHPTRLVL 76
F++W+P LA S + I+ +G+ C V + W P L
Sbjct: 21 FLAWNPAGTLLA----SCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYL 76
Query: 77 AVGWETGEVTVF--NKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLLLWRLDQ 134
A ++ N+ D E T H ++ + W+PSGN L + R + +W +D+
Sbjct: 77 ASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDE 136
Query: 135 RGRVQGTPLLKHEYGKHLTHCIFRLPPPGEDLVQLAKAAVSGDEKALDMFNWKKSSSGSL 194
+ +L + + + + H ++ P ++L+ A+ S D+ + ++ ++
Sbjct: 137 EDEYECVSVL-NSHTQDVKHVVWH---PSQELL----ASASYDD-TVKLYREEEDDWVCC 187
Query: 195 LKMGSHEGLLFFVSLMDGTVHYVDEKGKTTQVVSADSTIQM-LFYMEKREALVVVTENLR 253
+ HE ++ ++ D G+ S D T+++ Y+ E V + +
Sbjct: 188 ATLEGHESTVWSLAF--------DPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGS-- 237
Query: 254 LSLYTVPPEGKAEEVMKVKLSGKTGRRA-DIALIE-GSLLVMAVGEAALRFWDIERG--- 308
P K LSG R DIA + L A G+ A+R + +
Sbjct: 238 ------DPSWKC----ICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDP 287
Query: 309 ENYILSPDEKFGFEKGENMNCVCY-CKVKGLLAAGTDRGRVAMWR 352
+ S +++NCV + K GLLA+ +D G VA W+
Sbjct: 288 QQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDDGEVAFWK 332
>gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]
Length = 1170
Score = 38.5 bits (88), Expect = 0.048
Identities = 21/85 (24%), Positives = 39/85 (45%)
Query: 844 ELEARVAVLATQLGMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHLRST 903
+L +A + ++GM E A + KC + +W +A+++A++H + S
Sbjct: 846 KLLPEIAQMFVRVGMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSL 905
Query: 904 YHRYAGHLEASADCSRALSYYEKSD 928
RYA HL A+ Y K++
Sbjct: 906 LARYASHLLEKNKTLDAIELYRKAN 930
Score = 32.7 bits (73), Expect = 2.6
Identities = 58/240 (24%), Positives = 89/240 (37%), Gaps = 33/240 (13%)
Query: 1028 QAVHFYTRAQAFKNAIRLCKE-NGLDDQLMNLALLSSPEDMIEAARYY------EEKGVQ 1080
Q + YT QAF CK+ G+ LLS E Y+ E ++
Sbjct: 697 QKLDLYTAEQAFVR----CKDYQGIKFVKRLGKLLSESMKQAEVVGYFGRFEEAERTYLE 752
Query: 1081 MDR---AVMLYHKAGHFSKALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIEHS 1137
MDR A+ L K G + + L+L L+ + D D++ D+F +
Sbjct: 753 MDRRDLAIGLRLKLGDWFRVLQL---------LKTGSGDADDSLLEQANNAIGDYFADRQ 803
Query: 1138 QYERAVELLLAARKYQEALQLCLGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQIAD 1197
++ AV+ + R QE L C M E E + ++ LPE + LL +IA
Sbjct: 804 KWLNAVQYYVQGRN-QERLAECY--YMLEDYEGLENLAIS-----LPENHK--LLPEIAQ 853
Query: 1198 CCMRQGSYHLATKKYTQAGNKLKAMRALLKSGDTEKITFFASVSRQKEIYIMAANYLQSL 1257
+R G A + + A+ + K A KEI + A Y L
Sbjct: 854 MFVRVGMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSLLARYASHL 913
>gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]
Length = 1181
Score = 38.5 bits (88), Expect = 0.048
Identities = 21/85 (24%), Positives = 39/85 (45%)
Query: 844 ELEARVAVLATQLGMLEDAEQLYRKCKRHDLLNKFYQAAGRWQEALQVAEHHDRVHLRST 903
+L +A + ++GM E A + KC + +W +A+++A++H + S
Sbjct: 857 KLLPEIAQMFVRVGMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSL 916
Query: 904 YHRYAGHLEASADCSRALSYYEKSD 928
RYA HL A+ Y K++
Sbjct: 917 LARYASHLLEKNKTLDAIELYRKAN 941
Score = 32.7 bits (73), Expect = 2.6
Identities = 58/240 (24%), Positives = 89/240 (37%), Gaps = 33/240 (13%)
Query: 1028 QAVHFYTRAQAFKNAIRLCKE-NGLDDQLMNLALLSSPEDMIEAARYY------EEKGVQ 1080
Q + YT QAF CK+ G+ LLS E Y+ E ++
Sbjct: 708 QKLDLYTAEQAFVR----CKDYQGIKFVKRLGKLLSESMKQAEVVGYFGRFEEAERTYLE 763
Query: 1081 MDR---AVMLYHKAGHFSKALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIEHS 1137
MDR A+ L K G + + L+L L+ + D D++ D+F +
Sbjct: 764 MDRRDLAIGLRLKLGDWFRVLQL---------LKTGSGDADDSLLEQANNAIGDYFADRQ 814
Query: 1138 QYERAVELLLAARKYQEALQLCLGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQIAD 1197
++ AV+ + R QE L C M E E + ++ LPE + LL +IA
Sbjct: 815 KWLNAVQYYVQGRN-QERLAECY--YMLEDYEGLENLAIS-----LPENHK--LLPEIAQ 864
Query: 1198 CCMRQGSYHLATKKYTQAGNKLKAMRALLKSGDTEKITFFASVSRQKEIYIMAANYLQSL 1257
+R G A + + A+ + K A KEI + A Y L
Sbjct: 865 MFVRVGMCEQAVTAFLKCSQPKAAVDTCVHLNQWNKAVELAKNHSMKEIGSLLARYASHL 924
>gi|12962937 achalasia, adrenocortical insufficiency, alacrimia
(Allgrove, triple-A) [Homo sapiens]
Length = 546
Score = 37.0 bits (84), Expect = 0.14
Identities = 34/108 (31%), Positives = 45/108 (41%), Gaps = 13/108 (12%)
Query: 22 SWHPVHPFLAVAYISTTSTGSVDIYLEQGECVPDTHVERPFRVASLCWHP-TRLVLAVGW 80
+WHP AVA + SV +Y VP VASL W P + VLAV
Sbjct: 158 AWHPHTNKFAVALLDD----SVRVYNASSTIVPSLKHRLQRNVASLAWKPLSASVLAVAC 213
Query: 81 E------TGEVTVFNKQDKEQHTMPLTHTAD--ITVLRWSPSGNCLLS 120
+ T + T + + L+H +T L W+PSG LLS
Sbjct: 214 QSCILIWTLDPTSLSTRPSSGCAQVLSHPGHTPVTSLAWAPSGGRLLS 261
>gi|22907052 actin related protein 2/3 complex subunit 1A [Homo
sapiens]
Length = 370
Score = 36.6 bits (83), Expect = 0.18
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 19 SFISWHPVHPFLAVAYISTTSTGSVDIYLEQGECVPDTHVERPFR--VASLCWHPTRLVL 76
+F+ W P+ AV S SV + + + H+++P R V SL WHP ++L
Sbjct: 100 TFVKWSPLENKFAVG--SGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLL 157
Query: 77 AVGWETGEVTVFNKQDKEQHTMP 99
A G + VF+ KE P
Sbjct: 158 AAGSCDFKCRVFSAYIKEVDEKP 180
>gi|148727341 serine/threonine kinase receptor associated protein
[Homo sapiens]
Length = 350
Score = 36.6 bits (83), Expect = 0.18
Identities = 33/125 (26%), Positives = 48/125 (38%), Gaps = 16/125 (12%)
Query: 54 PDTHVERPFRVASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSP 113
P E P + S HP + L G E ++ ++ E+ H I +R+SP
Sbjct: 216 PIKSFEAPATINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSP 275
Query: 114 SGNCLLSGDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPPPGEDLVQLAKAA 173
G SG G L LW+ ++ YG L C+ P ED +LAK
Sbjct: 276 DGELYASGSEDGTLRLWQ----------TVVGKTYG--LWKCVL----PEEDSGELAKPK 319
Query: 174 VSGDE 178
+ E
Sbjct: 320 IGFPE 324
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 36.2 bits (82), Expect = 0.24
Identities = 84/400 (21%), Positives = 145/400 (36%), Gaps = 69/400 (17%)
Query: 845 LEARVAVLATQLGMLEDA---EQLYRKCKRHDLLNKFYQAAGRWQEA-------LQVAEH 894
+E + QL ML+ E + + + + L Y+A G ++EA L VA+
Sbjct: 850 MEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQS 909
Query: 895 HDRVHLRSTYHRYAGH-LEASADCSRALSYYEKSDTHRFEVPRMLSEDLPSLELY----- 948
+R+ ++ +R G+ A +AL +EK R V L E + Y
Sbjct: 910 LNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEK----RLVVAHELGEAFNKAQAYGELGS 965
Query: 949 ---------------------VNKMKDKTLWRWWAQYL----ESQGEMDAALHYYELARD 983
MKD+ L A L + GE D AL Y++L
Sbjct: 966 LHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQL--- 1022
Query: 984 HFSLVRIHCFQGNVQKAAQIANET------GNLAASYHLARQYESQEEVGQAVHFYTRAQ 1037
++Q A + N T GNL +Y +E + V Q H AQ
Sbjct: 1023 ------------DLQIAEETNNPTCQGRAYGNLGLTYESLGTFE-RAVVYQEQHLSIAAQ 1069
Query: 1038 AFKNAIRLCKENGLDDQLMNLALLSSPEDMI-EAARYYEEKGVQMDRAVMLYHKAGHFSK 1096
A + + L L S + E R E+ G + D A + +
Sbjct: 1070 MNDLAAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWA 1129
Query: 1097 ALELAFATQQFVALQLIAEDLDETSDPALLARCSDFFIEHSQYERAVELLLAARKYQEAL 1156
+ L A Q + E + + + + S F ++ S Y+ +L++ + EAL
Sbjct: 1130 SGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEAL 1189
Query: 1157 QLC-LGQNMSITEEMAEKMTVAKDSSDLPEESRRELLEQI 1195
+ G+ + + + E+ T +DS + ++LE +
Sbjct: 1190 AVAERGRTRAFADLLVERQTGQQDSDPYSPVTIDQILEMV 1229
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 36.2 bits (82), Expect = 0.24
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 61 PFRVASLCWHPTR-LVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLL 119
P ++ + HP + L + + G + N+ K H+M + H +T L P+G L+
Sbjct: 644 PTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSM-VAHLDAVTCLAVDPNGAFLM 702
Query: 120 SGDRLGVLLLWRLDQRGRVQGTPL--LKHEYGKHLTHC 155
SG L LW LD + VQ KHE H C
Sbjct: 703 SGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVAC 740
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 36.2 bits (82), Expect = 0.24
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 61 PFRVASLCWHPTR-LVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLL 119
P ++ + HP + L + + G + N+ K H+M + H +T L P+G L+
Sbjct: 637 PTQINQVVSHPNQPLTITAHDDRGIRFLDNRTGKPVHSM-VAHLDAVTCLAVDPNGAFLM 695
Query: 120 SGDRLGVLLLWRLDQRGRVQGTPL--LKHEYGKHLTHC 155
SG L LW LD + VQ KHE H C
Sbjct: 696 SGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVAC 733
>gi|110227615 echinoderm microtubule associated protein like 3 [Homo
sapiens]
Length = 896
Score = 35.8 bits (81), Expect = 0.31
Identities = 19/68 (27%), Positives = 35/68 (51%)
Query: 69 WHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLL 128
+HP+ V+AVG TG V + + +E + + ++V+R+SP G L G V+
Sbjct: 646 FHPSGAVVAVGLNTGRWLVLDTETREIVSDVIDGNEQLSVVRYSPDGLYLAIGSHDNVIY 705
Query: 129 LWRLDQRG 136
++ + G
Sbjct: 706 IYSVSSDG 713
>gi|19913369 transducin beta-like 3 [Homo sapiens]
Length = 808
Score = 35.8 bits (81), Expect = 0.31
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 11/134 (8%)
Query: 23 WHPVH--PFLAVAYISTTS---TGSVDIYLEQGECVPD--THVER--PFRVASLCWHP-- 71
W +H P +A+ T++ TG D + + V TH R P V + +HP
Sbjct: 104 WKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDP 163
Query: 72 TRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLLLWR 131
TRL+L + V++ QD+ + H + +T L +S G+ +LS R + ++W
Sbjct: 164 TRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWD 223
Query: 132 LDQRGRVQGTPLLK 145
L + P+ +
Sbjct: 224 LQSCQATRTVPVFE 237
>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
Length = 2627
Score = 35.4 bits (80), Expect = 0.41
Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 61 PFRVASLCWHPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLS 120
P R A++ T ++ E G V ++ + T +A +T + W+P G+ +S
Sbjct: 2240 PVRAAAVS--ETSGLMLTASEDGSVRLWQVPKEADDTCIPRSSAAVTAVAWAPDGSMAVS 2297
Query: 121 GDRLGVLLLWR 131
G++ G L+LW+
Sbjct: 2298 GNQAGELILWQ 2308
>gi|120587023 down-regulated in metastasis [Homo sapiens]
Length = 2785
Score = 35.4 bits (80), Expect = 0.41
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
Query: 1108 VALQLIAEDLDETSDPALLARCSDF---FIEHSQYERAVELLLAARKYQEALQL-CLGQN 1163
VA++ +A DLD+ LA C F++ S E+ V+ LL A K L+L C +
Sbjct: 2516 VAIKFLASDLDQKMKSISLASCHQLHSKFLDQSLGEQVVKNLLFAAKVLYLLELYCEDKQ 2575
Query: 1164 MSITEEMAEK------MTVAKDSSDLPEESRRELLEQI 1195
I E++ E+ + A + ++ E + E+ E++
Sbjct: 2576 SKIKEDLEEQEALEDGVACADEKAESDGEEKEEVKEEL 2613
>gi|89036565 PREDICTED: similar to Temporarily Assigned Gene name
family member (tag-184) [Homo sapiens]
Length = 2785
Score = 35.4 bits (80), Expect = 0.41
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 10/98 (10%)
Query: 1108 VALQLIAEDLDETSDPALLARCSDF---FIEHSQYERAVELLLAARKYQEALQL-CLGQN 1163
VA++ +A DLD+ LA C F++ S E+ V+ LL A K L+L C +
Sbjct: 2516 VAIKFLASDLDQKMKSISLASCHQLHSKFLDQSLGEQVVKNLLFAAKVLYLLELYCEDKQ 2575
Query: 1164 MSITEEMAEK------MTVAKDSSDLPEESRRELLEQI 1195
I E++ E+ + A + ++ E + E+ E++
Sbjct: 2576 SKIKEDLEEQEALEDGVACADEKAESDGEEKEEVKEEL 2613
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 35.4 bits (80), Expect = 0.41
Identities = 32/121 (26%), Positives = 50/121 (41%), Gaps = 15/121 (12%)
Query: 22 SWHPVHPFLA---------VAYISTTST-GSVDIYLEQGECVPDTHVERPFR--VASLCW 69
+W+PV LA + +S ST GS + L C+ + + P V SL W
Sbjct: 176 AWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRH--CIREGGQDVPSNKDVTSLDW 233
Query: 70 HPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLLL 129
+ +LA G G ++ K T+ H I L+W+ GN +LS ++
Sbjct: 234 NSEGTLLATGSYDGFARIWTKDGNLASTLG-QHKGPIFALKWNKKGNFILSAGVDKTTII 292
Query: 130 W 130
W
Sbjct: 293 W 293
Score = 33.5 bits (75), Expect = 1.5
Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 21/101 (20%)
Query: 102 HTADITVLRWSPSGNCLLSGDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPP 161
H +++ + W+P + L SG +W L + T L+ L HCI
Sbjct: 168 HESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLV-------LRHCI---RE 217
Query: 162 PGEDLVQLAKAAVSGDEKALDMFNWKKSSSGSLLKMGSHEG 202
G+D+ K + +W +S G+LL GS++G
Sbjct: 218 GGQDV---------PSNKDVTSLDW--NSEGTLLATGSYDG 247
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 35.4 bits (80), Expect = 0.41
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 21/101 (20%)
Query: 102 HTADITVLRWSPSGNCLLSGDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPP 161
H +++ + W+P + L SG +W L++ T L+ L HCI
Sbjct: 178 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLV-------LRHCI---RE 227
Query: 162 PGEDLVQLAKAAVSGDEKALDMFNWKKSSSGSLLKMGSHEG 202
G D+ K + +W +S G+LL MGS++G
Sbjct: 228 GGHDV---------PSNKDVTSLDW--NSDGTLLAMGSYDG 257
Score = 32.3 bits (72), Expect = 3.4
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 15/121 (12%)
Query: 22 SWHPVHPFLAVAYISTTST----------GSVDIYLEQGECVPDTHVERPFR--VASLCW 69
+W+PV LA +T+ GS + L C+ + + P V SL W
Sbjct: 186 AWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH--CIREGGHDVPSNKDVTSLDW 243
Query: 70 HPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLLL 129
+ +LA+G G ++ + T+ H I L+W+ GN +LS ++
Sbjct: 244 NSDGTLLAMGSYDGFARIWTENGNLASTLG-QHKGPIFALKWNKKGNYVLSAGVDKTTII 302
Query: 130 W 130
W
Sbjct: 303 W 303
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 35.4 bits (80), Expect = 0.41
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 21/101 (20%)
Query: 102 HTADITVLRWSPSGNCLLSGDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPP 161
H +++ + W+P + L SG +W L++ T L+ L HCI
Sbjct: 178 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLV-------LRHCI---RE 227
Query: 162 PGEDLVQLAKAAVSGDEKALDMFNWKKSSSGSLLKMGSHEG 202
G D+ K + +W +S G+LL MGS++G
Sbjct: 228 GGHDV---------PSNKDVTSLDW--NSDGTLLAMGSYDG 257
Score = 32.3 bits (72), Expect = 3.4
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 15/121 (12%)
Query: 22 SWHPVHPFLAVAYISTTST----------GSVDIYLEQGECVPDTHVERPFR--VASLCW 69
+W+PV LA +T+ GS + L C+ + + P V SL W
Sbjct: 186 AWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH--CIREGGHDVPSNKDVTSLDW 243
Query: 70 HPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLLL 129
+ +LA+G G ++ + T+ H I L+W+ GN +LS ++
Sbjct: 244 NSDGTLLAMGSYDGFARIWTENGNLASTLG-QHKGPIFALKWNKKGNYVLSAGVDKTTII 302
Query: 130 W 130
W
Sbjct: 303 W 303
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 35.4 bits (80), Expect = 0.41
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 21/101 (20%)
Query: 102 HTADITVLRWSPSGNCLLSGDRLGVLLLWRLDQRGRVQGTPLLKHEYGKHLTHCIFRLPP 161
H +++ + W+P + L SG +W L++ T L+ L HCI
Sbjct: 178 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLV-------LRHCI---RE 227
Query: 162 PGEDLVQLAKAAVSGDEKALDMFNWKKSSSGSLLKMGSHEG 202
G D+ K + +W +S G+LL MGS++G
Sbjct: 228 GGHDV---------PSNKDVTSLDW--NSDGTLLAMGSYDG 257
Score = 32.3 bits (72), Expect = 3.4
Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 15/121 (12%)
Query: 22 SWHPVHPFLAVAYISTTST----------GSVDIYLEQGECVPDTHVERPFR--VASLCW 69
+W+PV LA +T+ GS + L C+ + + P V SL W
Sbjct: 186 AWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH--CIREGGHDVPSNKDVTSLDW 243
Query: 70 HPTRLVLAVGWETGEVTVFNKQDKEQHTMPLTHTADITVLRWSPSGNCLLSGDRLGVLLL 129
+ +LA+G G ++ + T+ H I L+W+ GN +LS ++
Sbjct: 244 NSDGTLLAMGSYDGFARIWTENGNLASTLG-QHKGPIFALKWNKKGNYVLSAGVDKTTII 302
Query: 130 W 130
W
Sbjct: 303 W 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,218,460
Number of Sequences: 37866
Number of extensions: 2409821
Number of successful extensions: 6576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 6360
Number of HSP's gapped (non-prelim): 278
length of query: 1462
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1347
effective length of database: 13,892,928
effective search space: 18713774016
effective search space used: 18713774016
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.