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Search of human proteins with 38348414
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38348414 von Willebrand factor C domain containing 2 [Homo
sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38348414 von Willebrand factor C domain containing 2 [Homo sa... 704 0.0
gi|122937446 von Willebrand factor C domain-containing protein 2... 262 3e-70
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 85 1e-16
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 79 5e-15
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 79 5e-15
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 77 2e-14
gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] 76 5e-14
gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] 76 5e-14
gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] 76 5e-14
gi|108773804 Fraser syndrome 1 [Homo sapiens] 70 2e-12
gi|40353769 chordin-like 2 [Homo sapiens] 62 5e-10
gi|37693519 BMP-binding endothelial regulator precursor protein ... 62 5e-10
gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens] 60 3e-09
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 57 2e-08
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 57 2e-08
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 57 2e-08
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 57 2e-08
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 57 2e-08
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 52 6e-07
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 52 6e-07
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 52 7e-07
gi|30089980 chordin [Homo sapiens] 51 1e-06
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 48 1e-05
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 48 1e-05
gi|109150416 peroxidasin [Homo sapiens] 47 3e-05
gi|126517478 peroxidasin homolog-like [Homo sapiens] 47 3e-05
gi|161019170 mucin 5AC [Homo sapiens] 45 9e-05
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 45 9e-05
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 45 1e-04
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 44 1e-04
>gi|38348414 von Willebrand factor C domain containing 2 [Homo
sapiens]
Length = 325
Score = 704 bits (1817), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MPSSTAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHATRDGPGRVN 60
MPSSTAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHATRDGPGRVN
Sbjct: 1 MPSSTAMAVGALSSSLLVTCCLMVALCSPSIPLEKLAQAPEQPGQEKREHATRDGPGRVN 60
Query: 61 ELGRPARDEGGSGRDWKSKSGRGLAGREPWSKLKQAWVSQGGGAKAGDLQVRPRGDTPQA 120
ELGRPARDEGGSGRDWKSKSGRGLAGREPWSKLKQAWVSQGGGAKAGDLQVRPRGDTPQA
Sbjct: 61 ELGRPARDEGGSGRDWKSKSGRGLAGREPWSKLKQAWVSQGGGAKAGDLQVRPRGDTPQA 120
Query: 121 EALAAAAQDAIGPELAPTPEPPEEYVYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLC 180
EALAAAAQDAIGPELAPTPEPPEEYVYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLC
Sbjct: 121 EALAAAAQDAIGPELAPTPEPPEEYVYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLC 180
Query: 181 TEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCR 240
TEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCR
Sbjct: 181 TEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCR 240
Query: 241 CEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTIC 300
CEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTIC
Sbjct: 241 CEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTIC 300
Query: 301 HCTYEEGTWRIERQAMCTRHECRQM 325
HCTYEEGTWRIERQAMCTRHECRQM
Sbjct: 301 HCTYEEGTWRIERQAMCTRHECRQM 325
>gi|122937446 von Willebrand factor C domain-containing protein
2-like [Homo sapiens]
Length = 222
Score = 262 bits (669), Expect = 3e-70
Identities = 108/181 (59%), Positives = 136/181 (75%), Gaps = 4/181 (2%)
Query: 143 EEYVYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHV 202
+ ++ DYRGKGCVD+SGFVY +GE+F PG S CPC+C +GP+C QPECP++HP+C V
Sbjct: 41 DNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKV 100
Query: 203 DTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262
+ + CCP+CKE KN+CE+ GK Y+ LEEF SPCE CRCE + EV C V+ C ECV+P
Sbjct: 101 EHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNP 160
Query: 263 VYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHEC 322
VYEP+QCCP+CKNGPNCFA T +IPAG EVK DEC ICHC G W + A C++ EC
Sbjct: 161 VYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDECNICHC--HNGDW--WKPAQCSKREC 216
Query: 323 R 323
+
Sbjct: 217 Q 217
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 84.7 bits (208), Expect = 1e-16
Identities = 58/178 (32%), Positives = 77/178 (43%), Gaps = 27/178 (15%)
Query: 153 KGCVDESGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQC 211
+GC ++G Y GE F+P AC C C E C Q CPR C + CCP C
Sbjct: 136 RGC-SQNGQTYGNGETFSP--DACTTCRCLEGTITCNQKPCPR--GPC--PEPGACCPHC 188
Query: 212 KERKNYCEFRGKTYQTLEEFVVS--PCERCRCEANGEVLCTVSACPQTECVDPVYEPDQC 269
K C++ G+ Y+ F+ S PC +C C V C CP + C +PV P C
Sbjct: 189 KPG---CDYEGQLYEEGVTFLSSSNPCLQCTC-LRSRVRCMALKCPPSPCPEPVLRPGHC 244
Query: 270 CPICKNGPNCFAETAVIPAGREVKT--DECTICHCTYEEGTWRIERQAMCTRHECRQM 325
CP C+ C + G+E T D C IC C +E C + EC +
Sbjct: 245 CPTCQ---GCTEGGSHWEHGQEWTTPGDPCRICRC--------LEGHIQCRQRECASL 291
Score = 77.4 bits (189), Expect = 2e-14
Identities = 53/168 (31%), Positives = 68/168 (40%), Gaps = 22/168 (13%)
Query: 166 GEKFAPG----PSACPC---LCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYC 218
GE+FA G P PC +C + P C CP + CCP C C
Sbjct: 428 GEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDS----C 483
Query: 219 EFRGKTYQTLEEFVV--SPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNG 276
+ + Y + F SPC C C+ +G V C++ CP T C P P QCCP C
Sbjct: 484 TYHSQVYANGQNFTDADSPCHACHCQ-DGTVTCSLVDCPPTTCARPQSGPGQCCPRC--- 539
Query: 277 PNCFAETAVIPAGREVK--TDECTICHCTYEEGTWRIERQAMCTRHEC 322
P+C E V G D C C C +EG + + C R C
Sbjct: 540 PDCILEEEVFVDGESFSHPRDPCQECRC--QEGHAHCQPRP-CPRAPC 584
Score = 72.8 bits (177), Expect = 4e-13
Identities = 55/191 (28%), Positives = 76/191 (39%), Gaps = 30/191 (15%)
Query: 136 APTPEPPEEYVYPDYRGKGCVDESGFVYAIGEKFA-PGPSACPCLCTEEGPLCAQPECPR 194
+P PEP + +GC E G + G+++ PG C C E C Q EC
Sbjct: 232 SPCPEPVLRPGHCCPTCQGCT-EGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECAS 290
Query: 195 LHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVVS-PCERCRCEANGEVLCTVSA 253
L P CCP C + C G+ +++ E PC CRC ANG V C
Sbjct: 291 LCPYPARPLPGTCCPVC----DGCFLNGREHRSGEPVGSGDPCSHCRC-ANGSVQCEPLP 345
Query: 254 CPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYE-EGTWRIE 312
CP C P P QCCP+C D C Y+ + T+R++
Sbjct: 346 CPPVPCRHPGKIPGQCCPVC---------------------DGCEYQGHQYQSQETFRLQ 384
Query: 313 RQAMCTRHECR 323
+ +C R C+
Sbjct: 385 ERGLCVRCSCQ 395
Score = 68.9 bits (167), Expect = 6e-12
Identities = 50/148 (33%), Positives = 60/148 (40%), Gaps = 15/148 (10%)
Query: 159 SGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYC 218
+G + GE G C C C CP + R QCCP C + C
Sbjct: 313 NGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC----DGC 368
Query: 219 EFRGKTYQTLEEFVVSP---CERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKN 275
E++G YQ+ E F + C RC C+A GEV C CP T C P Q CP C+
Sbjct: 369 EYQGHQYQSQETFRLQERGLCVRCSCQA-GEVSCEEQECPVTPCALPA-SGRQLCPACEL 426
Query: 276 GPNCFAE-TAVIPAGREVKTDECTICHC 302
FAE P GR CT C C
Sbjct: 427 DGEEFAEGVQWEPDGR-----PCTACVC 449
Score = 67.0 bits (162), Expect = 2e-11
Identities = 42/120 (35%), Positives = 49/120 (40%), Gaps = 11/120 (9%)
Query: 162 VYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQ-CKERKNYCE 219
V+ GE F+ C C C E C CPR C H CCP C C
Sbjct: 548 VFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAP--CAHPLPGTCCPNDCSG----CA 601
Query: 220 FRGKTYQTLEEFV--VSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGP 277
F GK Y + +F PC CRC +G V C C C +PV P +CCP C P
Sbjct: 602 FGGKEYPSGADFPHPSDPCRLCRC-LSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAAP 660
Score = 52.8 bits (125), Expect = 4e-07
Identities = 35/110 (31%), Positives = 44/110 (40%), Gaps = 12/110 (10%)
Query: 167 EKFAPGPSAC-PCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTY 225
E F+P C CLC + C + CP C H CCP C + C ++GK +
Sbjct: 677 EYFSPPGDPCRRCLCLDGSVSCQRLPCP--PAPCAHPRQGPCCPSC----DGCLYQGKEF 730
Query: 226 QTLEEF--VVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPIC 273
+ E F + C C C G V C AC C P CCP C
Sbjct: 731 ASGERFPSPTAACHLCLC-WEGSVSCEPKACAPALC--PFPARGDCCPDC 777
Score = 34.3 bits (77), Expect = 0.16
Identities = 27/80 (33%), Positives = 32/80 (40%), Gaps = 11/80 (13%)
Query: 139 PEPPEEYVYPDYRGKGCVDESGFVY-----AIGEKFAPGPSACP-CLCTEEGPLCAQPEC 192
P PP +P +G C G +Y A GE+F +AC CLC E C C
Sbjct: 702 PCPPAPCAHPR-QGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKAC 760
Query: 193 -PRLHPRCIHVDTSQCCPQC 211
P L C CCP C
Sbjct: 761 APAL---CPFPARGDCCPDC 777
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 79.0 bits (193), Expect = 5e-15
Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 13/153 (8%)
Query: 128 QDAIGPELAPTPEPPE---EYVYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEG 184
QD+ P+ P P P+Y C ++ G ++ E + P C+C +
Sbjct: 727 QDSCCPQCTDQPFRPSLSRNNSVPNY----CKNDEGDIFLAAESWKPDVCTS-CICIDSV 781
Query: 185 PLCAQPECPRLHPRCIHVDTSQCCPQCKE----RKNYCEFRGKTYQTLEEFVVSPCERCR 240
C CP + + QCCP C E +K C F GK Y E + + C C
Sbjct: 782 ISCFSESCPSVSCERPVLRKGQCCPYCIEDTIPKKVVCHFSGKAYADEERWDLDSCTHCY 841
Query: 241 CEANGEVLCTVSACPQTECVDPVYEPDQCCPIC 273
C G+ LC+ +CP CV+P+ CCP+C
Sbjct: 842 C-LQGQTLCSTVSCPPLPCVEPINVEGSCCPMC 873
Score = 65.1 bits (157), Expect = 8e-11
Identities = 42/146 (28%), Positives = 64/146 (43%), Gaps = 15/146 (10%)
Query: 173 PSACPCLCTEEG-PLCAQPECPRLHPRCIHVDTSQCCP--QC-KERKNYCEFRGKTYQTL 228
P+ C CL G P+C PR+ R +CC +C + K C F Y
Sbjct: 288 PTRCECLSGLCGFPVCEVGSTPRIVSRGDGTP-GKCCDVFECVNDTKPACVFNNVEYYDG 346
Query: 229 EEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPD-QCCPICK-------NGPNCF 280
+ F + C CRC+ G +C + C + C + Y P+ +CCP+C+ N C+
Sbjct: 347 DMFRMDNCRFCRCQ-GGVAICFTAQCGEINC-ERYYVPEGECCPVCEDPVYPFNNPAGCY 404
Query: 281 AETAVIPAGREVKTDECTICHCTYEE 306
A ++ G + D+CT C C E
Sbjct: 405 ANGLILAHGDRWREDDCTFCQCVNGE 430
Score = 60.5 bits (145), Expect = 2e-09
Identities = 49/175 (28%), Positives = 64/175 (36%), Gaps = 32/175 (18%)
Query: 155 CVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIH--VDTSQCCPQCK 212
C+ G + E + G C CL E +CA CP P C + + QCCP C
Sbjct: 608 CLTVDGHHHKNEESWHDGCRECYCLNGRE--MCALITCPV--PACGNPTIHPGQCCPSCA 663
Query: 213 E----------RKNYCEFRGKTYQTL-EEFVVSPCERCRCEANGEVLCTVSACPQTECVD 261
+ + C G Y E + + C +C C + G VLC CP C +
Sbjct: 664 DDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHS-GRVLCETEVCPPLLCQN 722
Query: 262 PVYEPDQCCPICKNGP--------NCFA------ETAVIPAGREVKTDECTICHC 302
P D CCP C + P N E + A K D CT C C
Sbjct: 723 PSRTQDSCCPQCTDQPFRPSLSRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCIC 777
Score = 57.4 bits (137), Expect = 2e-08
Identities = 42/160 (26%), Positives = 63/160 (39%), Gaps = 22/160 (13%)
Query: 178 CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKE------RKNYCEFRGKTYQTLEEF 231
C C +C +C ++ +V +CCP C++ C G + +
Sbjct: 357 CRCQGGVAICFTAQCGEINCERYYVPEGECCPVCEDPVYPFNNPAGCYANGLILAHGDRW 416
Query: 232 VVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICK-------NGPNCFAETA 284
C C+C NGE C + C QT C +PV P +CCP+C+ + P C +
Sbjct: 417 REDDCTFCQC-VNGERHCVATVCGQT-CTNPVKVPGECCPVCEEPTIITVDPPACGELSN 474
Query: 285 VIPAGRE----VKTDE--CTICHCTYEEGTWRIERQAMCT 318
G++ K D C C C E ER+ CT
Sbjct: 475 CTLTGKDCINGFKRDHNGCRTCQCINTEELCS-ERKQGCT 513
Score = 52.4 bits (124), Expect = 6e-07
Identities = 47/185 (25%), Positives = 67/185 (36%), Gaps = 43/185 (23%)
Query: 171 PGPSAC-PCLCTEEGPL----------------CAQPECPRLHPRCIHVDTSQCCP-QCK 212
P P C P +C + PL C + C ++ P D+ C +C+
Sbjct: 534 PRPKKCRPIICDKYCPLGLLKNKHGCDICRCKKCPELSCSKICPLGFQQDSHGCLICKCR 593
Query: 213 ERK---------NYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPV 263
E C + EE C C C NG +C + CP C +P
Sbjct: 594 EASASAGPPILSGTCLTVDGHHHKNEESWHDGCRECYC-LNGREMCALITCPVPACGNPT 652
Query: 264 YEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCT----YEEG-TWRIERQAMCT 318
P QCCP C A+ V+ ++ + +ICH + EG TW I+ CT
Sbjct: 653 IHPGQCCPSC-------ADDFVV---QKPELSTPSICHAPGGEYFVEGETWNIDSCTQCT 702
Query: 319 RHECR 323
H R
Sbjct: 703 CHSGR 707
>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
Length = 955
Score = 79.0 bits (193), Expect = 5e-15
Identities = 50/159 (31%), Positives = 76/159 (47%), Gaps = 15/159 (9%)
Query: 154 GC-VDESGFVYAIGEKFAPGPSACPCLCTEEGPL-CAQPECPRLHPRCIHVDTSQCCPQC 211
GC +D++G + IG+ ++PG C+C +G + C + +C P I + QCCP C
Sbjct: 567 GCSLDDNGVEFPIGQIWSPGDPCELCICQADGSVSCKRTDCVDSCPHPIRI-PGQCCPDC 625
Query: 212 KERKNYCEFRGKTYQTLEEF--VVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQC 269
C + G+ + E F V+ PC C C G V C+ CP T C P + +C
Sbjct: 626 SAG---CTYTGRIFYNNETFPSVLDPCLSCIC-LLGSVACSPVDCPIT-CTYPFHPDGEC 680
Query: 270 CPICKNGPNCFAETAVIPAGREVKTDE--CTICHCTYEE 306
CP+C+ +C E + G+ D+ CT C C E
Sbjct: 681 CPVCR---DCNYEGRKVANGQVFTLDDEPCTRCTCQLGE 716
Score = 63.2 bits (152), Expect = 3e-10
Identities = 46/162 (28%), Positives = 64/162 (39%), Gaps = 20/162 (12%)
Query: 154 GCVDESGFVYAIGEKFAPGPSAC-PCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCK 212
GC +G ++ E F C C+C C+ +CP H D +CCP C+
Sbjct: 628 GCT-YTGRIFYNNETFPSVLDPCLSCICLLGSVACSPVDCPITCTYPFHPD-GECCPVCR 685
Query: 213 ERKNYCEFRGKTYQTLEEFVVS--PCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCC 270
+ C + G+ + F + PC RC C+ GEV C C Q C DP P CC
Sbjct: 686 D----CNYEGRKVANGQVFTLDDEPCTRCTCQL-GEVSCEKVPC-QRACADPALLPGDCC 739
Query: 271 PIC---------KNGPNCFAETAVIPAGREVKTDECTICHCT 303
C K G + A AGR + D +C+
Sbjct: 740 SSCPDSLSPLEEKQGLSPHGNVAFSKAGRSLHGDTEAPVNCS 781
Score = 59.3 bits (142), Expect = 4e-09
Identities = 52/180 (28%), Positives = 68/180 (37%), Gaps = 25/180 (13%)
Query: 154 GCVDESGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCK 212
GC SG V A G+ F+P C C+C C PECP C + CC
Sbjct: 442 GCF-HSGVVRAEGDVFSPPNENCTVCVCLAGNVSCISPECP--SGPCQTPPQTDCCTCVP 498
Query: 213 ERKNYCEFRGKTYQTLEEFV--VSPCERCRCEANGEVLCTVSACPQTECVDPVYE--PDQ 268
R C F G+ Y F C C C+ NGEV C+ CP+ C + P Q
Sbjct: 499 VR---CYFHGRWYADGAVFSGGGDECTTCVCQ-NGEVECSFMPCPELACPREEWRLGPGQ 554
Query: 269 CCPICK-----NGPNCFAETAVIPAGREVKT-DECTICHCTYEEGTWRIERQAMCTRHEC 322
CC C+ G + P G+ D C +C C + + C R +C
Sbjct: 555 CCFTCQEPTPSTGCSLDDNGVEFPIGQIWSPGDPCELCIC-------QADGSVSCKRTDC 607
Score = 55.5 bits (132), Expect = 6e-08
Identities = 50/161 (31%), Positives = 65/161 (40%), Gaps = 35/161 (21%)
Query: 163 YAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLH-PRCI-HVDTSQCCPQCKERK---- 215
YA G F+ G C C+C C+ CP L PR + QCC C+E
Sbjct: 508 YADGAVFSGGGDECTTCVCQNGEVECSFMPCPELACPREEWRLGPGQCCFTCQEPTPSTG 567
Query: 216 -----NYCEFR-GKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVD----PVYE 265
N EF G+ + + PCE C C+A+G V +C +T+CVD P+
Sbjct: 568 CSLDDNGVEFPIGQIWSPGD-----PCELCICQADGSV-----SCKRTDCVDSCPHPIRI 617
Query: 266 PDQCCPICKNG----PNCFAETAVIPAGREVKTDECTICHC 302
P QCCP C G F P+ D C C C
Sbjct: 618 PGQCCPDCSAGCTYTGRIFYNNETFPS----VLDPCLSCIC 654
Score = 42.4 bits (98), Expect = 6e-04
Identities = 40/136 (29%), Positives = 46/136 (33%), Gaps = 17/136 (12%)
Query: 173 PSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFV 232
P C C + C + C I CCP C C G E V
Sbjct: 402 PGCSQCWCEDGKVTCEKVRCEAACSHPIPSRDGGCCPSC----TGCFHSGVV--RAEGDV 455
Query: 233 VSP----CERCRCEANGEVLCTVSACPQTEC-VDPVYEPDQCCPI-CKNGPNCFAETAVI 286
SP C C C A G V C CP C P + C P+ C +A+ AV
Sbjct: 456 FSPPNENCTVCVCLA-GNVSCISPECPSGPCQTPPQTDCCTCVPVRCYFHGRWYADGAVF 514
Query: 287 PAGREVKTDECTICHC 302
G DECT C C
Sbjct: 515 SGG----GDECTTCVC 526
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 77.4 bits (189), Expect = 2e-14
Identities = 53/168 (31%), Positives = 68/168 (40%), Gaps = 22/168 (13%)
Query: 166 GEKFAPG----PSACPC---LCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYC 218
GE+FA G P PC +C + P C CP + CCP C C
Sbjct: 370 GEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDS----C 425
Query: 219 EFRGKTYQTLEEFVV--SPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNG 276
+ + Y + F SPC C C+ +G V C++ CP T C P P QCCP C
Sbjct: 426 TYHSQVYANGQNFTDADSPCHACHCQ-DGTVTCSLVDCPPTTCARPQSGPGQCCPRC--- 481
Query: 277 PNCFAETAVIPAGREVK--TDECTICHCTYEEGTWRIERQAMCTRHEC 322
P+C E V G D C C C +EG + + C R C
Sbjct: 482 PDCILEEEVFVDGESFSHPRDPCQECRC--QEGHAHCQPRP-CPRAPC 526
Score = 72.4 bits (176), Expect = 5e-13
Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 29/172 (16%)
Query: 155 CVDESGFVYAIGEKFA-PGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKE 213
C E G + G+++ PG C C E C Q EC L P CCP C
Sbjct: 192 CCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVC-- 249
Query: 214 RKNYCEFRGKTYQTLEEFVVS-PCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPI 272
+ C G+ +++ E PC CRC ANG V C CP C P P QCCP+
Sbjct: 250 --DGCFLNGREHRSGEPVGSGDPCSHCRC-ANGSVQCEPLPCPPVPCRHPGKIPGQCCPV 306
Query: 273 CKNGPNCFAETAVIPAGREVKTDECTICHCTYE-EGTWRIERQAMCTRHECR 323
C D C Y+ + T+R++ + +C R C+
Sbjct: 307 C---------------------DGCEYQGHQYQSQETFRLQERGLCVRCSCQ 337
Score = 69.7 bits (169), Expect = 3e-12
Identities = 56/185 (30%), Positives = 77/185 (41%), Gaps = 20/185 (10%)
Query: 139 PEPPEEYVYPDYRGKGCVDESGFVY-----AIGEKFAPGPSACP-CLCTEEGPLCAQPEC 192
P PP +P +G C G +Y A GE+F +AC CLC E C C
Sbjct: 641 PCPPAPCAHPR-QGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKAC 699
Query: 193 -PRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVV--SPCERCRCEANGEVLC 249
P L P D CCP C + CE+ G++Y + +EF PC C C G V C
Sbjct: 700 APALCPFPARGD---CCPDC----DGCEYLGESYLSNQEFPDPREPCNLCTC-LGGFVTC 751
Query: 250 TVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTW 309
C C P+ CCP C+ TA + C++C C +EG+
Sbjct: 752 GRRPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTCSLCTC--QEGSM 809
Query: 310 RIERQ 314
R +++
Sbjct: 810 RCQKK 814
Score = 69.7 bits (169), Expect = 3e-12
Identities = 54/181 (29%), Positives = 75/181 (41%), Gaps = 24/181 (13%)
Query: 157 DESGFVYAIGEKFAPGPSACP-CLCTE--EGP---LCAQPECPRL----HPRCIHVDTSQ 206
+ G Y GE F PG C C+C EGP C + +CP L + +
Sbjct: 955 EHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQH 1014
Query: 207 CCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYE- 265
CCP C E + C + E PC C+C+ + LC ACP+ C P+ E
Sbjct: 1015 CCPTCAEALSNCS---EGLLGSELAPPDPCYTCQCQ-DLTWLCIHQACPELSC--PLSER 1068
Query: 266 ---PDQCCPICKNGP-NCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHE 321
P CCP+C+ +C + + +G D CT C C GT R + Q C+
Sbjct: 1069 HTPPGSCCPVCRAPTQSCVHQGREVASGERWTVDTCTSCSCM--AGTVRCQSQ-RCSPLS 1125
Query: 322 C 322
C
Sbjct: 1126 C 1126
Score = 68.9 bits (167), Expect = 6e-12
Identities = 50/148 (33%), Positives = 60/148 (40%), Gaps = 15/148 (10%)
Query: 159 SGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKNYC 218
+G + GE G C C C CP + R QCCP C + C
Sbjct: 255 NGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC----DGC 310
Query: 219 EFRGKTYQTLEEFVVSP---CERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKN 275
E++G YQ+ E F + C RC C+A GEV C CP T C P Q CP C+
Sbjct: 311 EYQGHQYQSQETFRLQERGLCVRCSCQA-GEVSCEEQECPVTPCALPA-SGRQLCPACEL 368
Query: 276 GPNCFAE-TAVIPAGREVKTDECTICHC 302
FAE P GR CT C C
Sbjct: 369 DGEEFAEGVQWEPDGR-----PCTACVC 391
Score = 67.8 bits (164), Expect = 1e-11
Identities = 48/148 (32%), Positives = 57/148 (38%), Gaps = 14/148 (9%)
Query: 162 VYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQ-CKERKNYCE 219
V+ GE F+ C C C E C CPR C H CCP C C
Sbjct: 490 VFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAP--CAHPLPGTCCPNDCSG----CA 543
Query: 220 FRGKTYQTLEEFV--VSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGP 277
F GK Y + +F PC CRC +G V C C C +PV P +CCP C
Sbjct: 544 FGGKEYPSGADFPHPSDPCRLCRC-LSGNVQCLARRCVPLPCPEPVLLPGECCPQCPAPA 602
Query: 278 NCFAETAVIPAGREVKT---DECTICHC 302
C A +E + D C C C
Sbjct: 603 GCPRPGAAHARHQEYFSPPGDPCRRCLC 630
Score = 66.2 bits (160), Expect = 4e-11
Identities = 47/153 (30%), Positives = 57/153 (37%), Gaps = 19/153 (12%)
Query: 173 PSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQC-CPQCKERKNYCEFRGKTYQTLEEF 231
P+ C C E C + CP C H C CP C C +G+ +Q EEF
Sbjct: 797 PTCSLCTCQEGSMRCQKKPCPPA--LCPHPSPGPCFCPVCHS----CLSQGREHQDGEEF 850
Query: 232 V--VSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAG 289
CE CRC+A G+V C CP C V E CCP C+ C A P G
Sbjct: 851 EGPAGSCEWCRCQA-GQVSCVRLQCPPLPCKLQVTERGSCCPRCR---GCLAHGEEHPEG 906
Query: 290 REVKTDECTICHCTYEEGTWRIERQAMCTRHEC 322
+ C EG C R +C
Sbjct: 907 SRWVPPDSACSSCVCHEGV------VTCARIQC 933
Score = 62.8 bits (151), Expect = 4e-10
Identities = 48/165 (29%), Positives = 62/165 (37%), Gaps = 35/165 (21%)
Query: 178 CLCTEEGPLC-----AQPECPRLHP----RCIHVDTSQCC------PQCKERKNYCEFRG 222
C C P C A PE R P C+ D + C P C+ C G
Sbjct: 87 CECHPASPQCWGLGRAWPEGARWEPDACTACVCQDGAAHCGPQAHLPHCRG----CSQNG 142
Query: 223 KTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAE 282
+TY E F C CRC G V C +C + C++ P +CCPIC C
Sbjct: 143 QTYGNGETFSPDACTTCRC-LTGAVQCQGPSCSELNCLESCTPPGECCPIC-----CTEG 196
Query: 283 TAVIPAGREVKT--DECTICHCTYEEGTWRIERQAMCTRHECRQM 325
+ G+E T D C IC C +E C + EC +
Sbjct: 197 GSHWEHGQEWTTPGDPCRICRC--------LEGHIQCRQRECASL 233
Score = 62.4 bits (150), Expect = 5e-10
Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 7/123 (5%)
Query: 165 IGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCI--HVDTSQCCPQCKERKNYCEFRG 222
+G + AP C C + LC CP L H CCP C+ C +G
Sbjct: 1031 LGSELAPPDPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQG 1090
Query: 223 KTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTEC---VDPVYEPDQCCPICKNGP-N 278
+ + E + V C C C A G V C C C P P CCP C P +
Sbjct: 1091 REVASGERWTVDTCTSCSCMA-GTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS 1149
Query: 279 CFA 281
C A
Sbjct: 1150 CMA 1152
Score = 55.8 bits (133), Expect = 5e-08
Identities = 48/172 (27%), Positives = 62/172 (36%), Gaps = 16/172 (9%)
Query: 137 PTPEP---PEEYVYPDYRGKGCVDESGFVYAIGEKFAPGPSAC-PCLCTEEGPLCAQPEC 192
P PEP P E GC E F+P C CLC + C + C
Sbjct: 583 PCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPC 642
Query: 193 PRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEF--VVSPCERCRCEANGEVLCT 250
P C H CCP C + C ++GK + + E F + C C C G V C
Sbjct: 643 P--PAPCAHPRQGPCCPSC----DGCLYQGKEFASGERFPSPTAACHLCLC-WEGSVSCE 695
Query: 251 VSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHC 302
AC C P CCP C +G E+ + + C +C C
Sbjct: 696 PKACAPALC--PFPARGDCCPDC-DGCEYLGESYLSNQEFPDPREPCNLCTC 744
Score = 55.1 bits (131), Expect = 8e-08
Identities = 51/196 (26%), Positives = 74/196 (37%), Gaps = 23/196 (11%)
Query: 133 PELAPTPEPPEEYVYPDYRGKGCVDESGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPE 191
P L P P P + + C+ + G + GE+F +C C C C + +
Sbjct: 818 PALCPHPSPGPCFCPVCH---SCLSQ-GREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQ 873
Query: 192 CPRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEEFVV--SPCERCRCEANGEVLC 249
CP L + + CCP+C+ C G+ + +V S C C C G V C
Sbjct: 874 CPPLPCKLQVTERGSCCPRCRG----CLAHGEEHPEGSRWVPPDSACSSCVCH-EGVVTC 928
Query: 250 TVSACPQTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVK--TDECTICHCTYE-E 306
C + C P P CCP C +C E G + D C +C C + E
Sbjct: 929 ARIQC-ISSCAQPRQGPHDCCPQCS---DCEHEGRKYEPGESFQPGADPCEVCICEPQPE 984
Query: 307 GTWRIERQAMCTRHEC 322
G + C R +C
Sbjct: 985 GPPSLR----CHRRQC 996
>gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens]
Length = 456
Score = 75.9 bits (185), Expect = 5e-14
Identities = 46/138 (33%), Positives = 65/138 (47%), Gaps = 28/138 (20%)
Query: 163 YAIGEKFAP-----GPSACP-CLCTEEGP-LCAQPECPRLHPRC-IHVDTSQCCPQC--- 211
Y +GE++ P G C C+C+E G LC++ CP +H +H+ CCP+C
Sbjct: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIP-HLCCPRCPDS 102
Query: 212 ------KERKNYCEFRGKTYQTLEEFVV---------SPCERCRCEANGEVLCTVSACPQ 256
K CE+ G TYQ E FV + C +C C + G V C + CP+
Sbjct: 103 LPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC-SEGNVYCGLKTCPK 161
Query: 257 TECVDPVYEPDQCCPICK 274
C PV PD CC +C+
Sbjct: 162 LTCAFPVSVPDSCCRVCR 179
Score = 66.2 bits (160), Expect = 4e-11
Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 22/129 (17%)
Query: 210 QCKERKNYCEFRGKTYQT-------LEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262
Q K + YC F+ K Y+ LE + + C C C NG VLC+ CP C+ P
Sbjct: 29 QVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP 88
Query: 263 VYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYE-------EGTWRIERQA 315
V+ P CCP C + ++ P +V + C TY+ EG ++ +
Sbjct: 89 VHIPHLCCPRCPD--------SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPN 140
Query: 316 MCTRHECRQ 324
CT+ C +
Sbjct: 141 QCTQCSCSE 149
>gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens]
Length = 457
Score = 75.9 bits (185), Expect = 5e-14
Identities = 46/138 (33%), Positives = 65/138 (47%), Gaps = 28/138 (20%)
Query: 163 YAIGEKFAP-----GPSACP-CLCTEEGP-LCAQPECPRLHPRC-IHVDTSQCCPQC--- 211
Y +GE++ P G C C+C+E G LC++ CP +H +H+ CCP+C
Sbjct: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIP-HLCCPRCPDS 102
Query: 212 ------KERKNYCEFRGKTYQTLEEFVV---------SPCERCRCEANGEVLCTVSACPQ 256
K CE+ G TYQ E FV + C +C C + G V C + CP+
Sbjct: 103 LPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC-SEGNVYCGLKTCPK 161
Query: 257 TECVDPVYEPDQCCPICK 274
C PV PD CC +C+
Sbjct: 162 LTCAFPVSVPDSCCRVCR 179
Score = 66.2 bits (160), Expect = 4e-11
Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 22/129 (17%)
Query: 210 QCKERKNYCEFRGKTYQT-------LEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262
Q K + YC F+ K Y+ LE + + C C C NG VLC+ CP C+ P
Sbjct: 29 QVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP 88
Query: 263 VYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYE-------EGTWRIERQA 315
V+ P CCP C + ++ P +V + C TY+ EG ++ +
Sbjct: 89 VHIPHLCCPRCPD--------SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPN 140
Query: 316 MCTRHECRQ 324
CT+ C +
Sbjct: 141 QCTQCSCSE 149
>gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens]
Length = 458
Score = 75.9 bits (185), Expect = 5e-14
Identities = 46/139 (33%), Positives = 65/139 (46%), Gaps = 29/139 (20%)
Query: 163 YAIGEKFAP-----GPSACP-CLCTEEGP-LCAQPECPRLHPRC-IHVDTSQCCPQCKE- 213
Y +GE++ P G C C+C+E G LC++ CP +H +H+ CCP+C E
Sbjct: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSPVHIP-HLCCPRCPED 102
Query: 214 ---------RKNYCEFRGKTYQTLEEFVV---------SPCERCRCEANGEVLCTVSACP 255
CE+ G TYQ E FV + C +C C + G V C + CP
Sbjct: 103 SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSC-SEGNVYCGLKTCP 161
Query: 256 QTECVDPVYEPDQCCPICK 274
+ C PV PD CC +C+
Sbjct: 162 KLTCAFPVSVPDSCCRVCR 180
Score = 67.8 bits (164), Expect = 1e-11
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 21/129 (16%)
Query: 210 QCKERKNYCEFRGKTYQT-------LEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262
Q K + YC F+ K Y+ LE + + C C C NG VLC+ CP C+ P
Sbjct: 29 QVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP 88
Query: 263 VYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYE-------EGTWRIERQA 315
V+ P CCP C E ++ P +V + C TY+ EG ++ +
Sbjct: 89 VHIPHLCCPRC-------PEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPN 141
Query: 316 MCTRHECRQ 324
CT+ C +
Sbjct: 142 QCTQCSCSE 150
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 70.5 bits (171), Expect = 2e-12
Identities = 45/160 (28%), Positives = 65/160 (40%), Gaps = 11/160 (6%)
Query: 162 VYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRL---HPRCIHVDTSQCCPQCKERKNYC 218
++ G ++A P + C C C CP L H + CCP C C
Sbjct: 101 IHEHGTEWASSPCSV-CSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPC 159
Query: 219 EFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP---VYEPDQCCPICKN 275
+ G +Q E++ +S C +C C NG C + C C V P +CCP C +
Sbjct: 160 SYEGHVFQDGEDWRLSRCAKCLCR-NGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQC-S 217
Query: 276 GPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQA 315
+C A V G + + CT C C + G R +QA
Sbjct: 218 ARSCSAAGQVYEHGEQWSENACTTCIC--DRGEVRCHKQA 255
Score = 69.3 bits (168), Expect = 4e-12
Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 6/122 (4%)
Query: 186 LCAQPECPRLHPRCIHVDTSQCCPQCKER-KNYCEFRGKTYQTLEEFVVSPCERCRCEAN 244
+C P+C + + +QCCP+C R C K ++ E+ SPC C C +
Sbjct: 62 VCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKIHEHGTEWASSPCSVCSCN-H 120
Query: 245 GEVLCTVSACPQTEC--VDPVYEPD-QCCPICKN-GPNCFAETAVIPAGREVKTDECTIC 300
GEV CT CP C + + P+ CCP+C G C E V G + + C C
Sbjct: 121 GEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKC 180
Query: 301 HC 302
C
Sbjct: 181 LC 182
Score = 62.8 bits (151), Expect = 4e-10
Identities = 48/177 (27%), Positives = 73/177 (41%), Gaps = 28/177 (15%)
Query: 148 PDYRGKGCVDESGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDT-- 204
P + C +G VY GE+++ +AC C+C C + C L RC +
Sbjct: 214 PQCSARSC-SAAGQVYEHGEQWSE--NACTTCICDRGEVRCHKQACLPL--RCGKGQSRA 268
Query: 205 ---SQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECV- 260
QCC +C C + G E + S CE C C+ +G+V C C + EC
Sbjct: 269 RRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCD-HGQVTCQTGECAKVECAR 327
Query: 261 --DPVYEPDQCCPIC--KNGPNCFAETAV-----------IPAGREVKTDECTICHC 302
+ ++ +CCP C +NG + ET IP G + + C +C C
Sbjct: 328 DEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCEC 384
Score = 42.4 bits (98), Expect = 6e-04
Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 236 CERCRCEANGEVLCTVSACPQTECVDPVYE-----PDQCCPIC--KNGPNCFAETAVIPA 288
C+ CRC + V+C + C +C E +QCCP C + +C E +
Sbjct: 46 CQSCRCHGD-IVICKPAVCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKIHEH 104
Query: 289 GREVKTDECTICHCTYEE 306
G E + C++C C + E
Sbjct: 105 GTEWASSPCSVCSCNHGE 122
>gi|40353769 chordin-like 2 [Homo sapiens]
Length = 451
Score = 62.4 bits (150), Expect = 5e-10
Identities = 39/141 (27%), Positives = 59/141 (41%), Gaps = 32/141 (22%)
Query: 166 GEKFAPGPSACP------------CLCTEEGPL-CAQPECPRLHPRCIHVDTSQCCPQCK 212
G++++PG S P C C+E + C + CP +H + QCCP+C
Sbjct: 37 GKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCV 96
Query: 213 ERKN---------YCEFRGKTYQTLEEF---------VVSPCERCRCEANGEVLCTVSAC 254
E C+ G YQ E F + + C C C G++ C ++ C
Sbjct: 97 EPHTPSGLRAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSC-TEGQIYCGLTTC 155
Query: 255 PQTECVDPVYEPDQCCPICKN 275
P+ C P+ PD CC CK+
Sbjct: 156 PEPGCPAPLPLPDSCCQACKD 176
Score = 50.8 bits (120), Expect = 2e-06
Identities = 25/64 (39%), Positives = 27/64 (42%), Gaps = 7/64 (10%)
Query: 217 YCEFRGKTYQT-------LEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQC 269
+C F GK Y LE + C RC C V C CP C PV EP QC
Sbjct: 32 FCLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQC 91
Query: 270 CPIC 273
CP C
Sbjct: 92 CPKC 95
Score = 34.3 bits (77), Expect = 0.16
Identities = 26/94 (27%), Positives = 33/94 (35%), Gaps = 16/94 (17%)
Query: 212 KERKNYCEFRGKTYQ-------TLEEFVVSPCERCRCEANGEVLCTVSACP-QTECVDPV 263
++ K C GKTY F PC C CE +G C CP + C P
Sbjct: 246 EKHKKACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCE-DGRQDCQRVTCPTEYPCRHPE 304
Query: 264 YEPDQCCPICKNGPNCFAETAVIPAGREVKTDEC 297
+CC IC E P E+ + C
Sbjct: 305 KVAGKCCKIC-------PEDKADPGHSEISSTRC 331
>gi|37693519 BMP-binding endothelial regulator precursor protein
[Homo sapiens]
Length = 685
Score = 62.4 bits (150), Expect = 5e-10
Identities = 53/170 (31%), Positives = 67/170 (39%), Gaps = 31/170 (18%)
Query: 154 GCVDESGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLH--PRCIHVDTSQCCPQ 210
GCV E G Y GE+F P S C C CT C + CP L H+ QCCP+
Sbjct: 165 GCVFE-GVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPGQCCPK 223
Query: 211 C-KERKNY------CEFRGKTYQTLEEFVVSPCERCRCEANGEVLCT-----VSACPQ-- 256
C +RK + C FR Y F+ C C C + V+C C Q
Sbjct: 224 CLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR-DSTVVCKRKCSHPGGCDQGQ 282
Query: 257 ----TECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHC 302
EC+ V P + +CK G F + G + CTIC C
Sbjct: 283 EGCCEECLLRV--PPEDIKVCKFGNKIFQD------GEMWSSINCTICAC 324
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/131 (29%), Positives = 53/131 (40%), Gaps = 13/131 (9%)
Query: 178 CLCTEEGPLCAQPECPRLHPRCIHV--DTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSP 235
C+C + C + +CP L C CC QCK C + G TY + ++ SP
Sbjct: 70 CVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKG----CTYEGNTYNSSFKW-QSP 124
Query: 236 CERCRCEANGEVLCTVSACP-QTECVDPVYEPDQCCPICKNGPNCFAETAVIPAGREVKT 294
E C E + T S C +P+ CCP C P C E G E +
Sbjct: 125 AEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMCCPTC---PGCVFEGVQYQEGEEFQP 181
Query: 295 D--ECTICHCT 303
+ +CT C CT
Sbjct: 182 EGSKCTKCSCT 192
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/110 (26%), Positives = 42/110 (38%), Gaps = 17/110 (15%)
Query: 178 CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQC-----KERKNYCEFRGKTYQTLEEFV 232
C C + +C + +C HP CC +C E C+F K +Q E +
Sbjct: 259 CTCRDSTVVCKR-KCS--HPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWS 315
Query: 233 VSPCERCRC-----EANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGP 277
C C C E + +S+CPQ + + CCPIC P
Sbjct: 316 SINCTICACVKGRTECRNKQCIPISSCPQGK----ILNRKGCCPICTEKP 361
>gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens]
Length = 377
Score = 59.7 bits (143), Expect = 3e-09
Identities = 27/71 (38%), Positives = 35/71 (49%), Gaps = 7/71 (9%)
Query: 210 QCKERKNYCEFRGKTYQT-------LEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262
Q K + YC F+ K Y+ LE + + C C C NG VLC+ CP C+ P
Sbjct: 29 QVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVHCLSP 88
Query: 263 VYEPDQCCPIC 273
V+ P CCP C
Sbjct: 89 VHIPHLCCPRC 99
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 26/172 (15%)
Query: 152 GKGCVDE---SGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQC 207
GK C + G V G+ + C C C +C + C +P VD C
Sbjct: 656 GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPT---VDLF-C 711
Query: 208 CPQCKER-KNYCEFR-GKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYE 265
CP+C R + C + G+T + V C++CRC GEV C CP EC +
Sbjct: 712 CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC-LQGEVDCWPLPCPDVECEFSILP 770
Query: 266 PDQCCPICKNGP------------NCFAETAVI--PAGREVK-TDECTICHC 302
++CCP C P C E V+ +K ECT+C C
Sbjct: 771 ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 822
Score = 52.4 bits (124), Expect = 6e-07
Identities = 48/182 (26%), Positives = 68/182 (37%), Gaps = 23/182 (12%)
Query: 160 GFVYAIGEKFAPGPSACPCLCTE---EGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKN 216
G Y E + G C CL E +C P+CP L +VD +CC +CK +
Sbjct: 301 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCP-LKSALAYVD-GKCCKECK---S 355
Query: 217 YCEFRGKTYQTLEEFVV----SPCERCRCEANGEVLCTVSACPQTECVD--PVYEPDQCC 270
C+F+G+TY E V C C+ L S CP +C + + CC
Sbjct: 356 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 415
Query: 271 PICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCT--------RHEC 322
+CK C + ++ +C C R E A C RH C
Sbjct: 416 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR-EDNAYCEDIDECAEGRHYC 474
Query: 323 RQ 324
R+
Sbjct: 475 RE 476
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 26/172 (15%)
Query: 152 GKGCVDE---SGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQC 207
GK C + G V G+ + C C C +C + C +P VD C
Sbjct: 632 GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPT---VDLF-C 687
Query: 208 CPQCKER-KNYCEFR-GKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYE 265
CP+C R + C + G+T + V C++CRC GEV C CP EC +
Sbjct: 688 CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC-LQGEVDCWPLPCPDVECEFSILP 746
Query: 266 PDQCCPICKNGP------------NCFAETAVI--PAGREVK-TDECTICHC 302
++CCP C P C E V+ +K ECT+C C
Sbjct: 747 ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 798
Score = 52.4 bits (124), Expect = 6e-07
Identities = 48/182 (26%), Positives = 68/182 (37%), Gaps = 23/182 (12%)
Query: 160 GFVYAIGEKFAPGPSACPCLCTE---EGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKN 216
G Y E + G C CL E +C P+CP L +VD +CC +CK +
Sbjct: 277 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCP-LKSALAYVD-GKCCKECK---S 331
Query: 217 YCEFRGKTYQTLEEFVV----SPCERCRCEANGEVLCTVSACPQTECVD--PVYEPDQCC 270
C+F+G+TY E V C C+ L S CP +C + + CC
Sbjct: 332 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 391
Query: 271 PICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCT--------RHEC 322
+CK C + ++ +C C R E A C RH C
Sbjct: 392 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR-EDNAYCEDIDECAEGRHYC 450
Query: 323 RQ 324
R+
Sbjct: 451 RE 452
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 26/172 (15%)
Query: 152 GKGCVDE---SGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQC 207
GK C + G V G+ + C C C +C + C +P VD C
Sbjct: 633 GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPT---VDLF-C 688
Query: 208 CPQCKER-KNYCEFR-GKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYE 265
CP+C R + C + G+T + V C++CRC GEV C CP EC +
Sbjct: 689 CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC-LQGEVDCWPLPCPDVECEFSILP 747
Query: 266 PDQCCPICKNGP------------NCFAETAVI--PAGREVK-TDECTICHC 302
++CCP C P C E V+ +K ECT+C C
Sbjct: 748 ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 799
Score = 52.4 bits (124), Expect = 6e-07
Identities = 48/182 (26%), Positives = 68/182 (37%), Gaps = 23/182 (12%)
Query: 160 GFVYAIGEKFAPGPSACPCLCTE---EGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKN 216
G Y E + G C CL E +C P+CP L +VD +CC +CK +
Sbjct: 278 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCP-LKSALAYVD-GKCCKECK---S 332
Query: 217 YCEFRGKTYQTLEEFVV----SPCERCRCEANGEVLCTVSACPQTECVD--PVYEPDQCC 270
C+F+G+TY E V C C+ L S CP +C + + CC
Sbjct: 333 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 392
Query: 271 PICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCT--------RHEC 322
+CK C + ++ +C C R E A C RH C
Sbjct: 393 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR-EDNAYCEDIDECAEGRHYC 451
Query: 323 RQ 324
R+
Sbjct: 452 RE 453
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 26/172 (15%)
Query: 152 GKGCVDE---SGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQC 207
GK C + G V G+ + C C C +C + C +P VD C
Sbjct: 683 GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPT---VDLF-C 738
Query: 208 CPQCKER-KNYCEFR-GKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYE 265
CP+C R + C + G+T + V C++CRC GEV C CP EC +
Sbjct: 739 CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC-LQGEVDCWPLPCPDVECEFSILP 797
Query: 266 PDQCCPICKNGP------------NCFAETAVI--PAGREVK-TDECTICHC 302
++CCP C P C E V+ +K ECT+C C
Sbjct: 798 ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 849
Score = 52.4 bits (124), Expect = 6e-07
Identities = 48/182 (26%), Positives = 68/182 (37%), Gaps = 23/182 (12%)
Query: 160 GFVYAIGEKFAPGPSACPCLCTE---EGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKN 216
G Y E + G C CL E +C P+CP L +VD +CC +CK +
Sbjct: 328 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCP-LKSALAYVD-GKCCKECK---S 382
Query: 217 YCEFRGKTYQTLEEFVV----SPCERCRCEANGEVLCTVSACPQTECVD--PVYEPDQCC 270
C+F+G+TY E V C C+ L S CP +C + + CC
Sbjct: 383 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 442
Query: 271 PICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCT--------RHEC 322
+CK C + ++ +C C R E A C RH C
Sbjct: 443 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR-EDNAYCEDIDECAEGRHYC 501
Query: 323 RQ 324
R+
Sbjct: 502 RE 503
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 26/172 (15%)
Query: 152 GKGCVDE---SGFVYAIGEKFAPGPSACP-CLCTEEGPLCAQPECPRLHPRCIHVDTSQC 207
GK C + G V G+ + C C C +C + C +P VD C
Sbjct: 633 GKNCTGDCIHDGKVKHNGQIWVLENDRCSVCSCQNGFVMCRRMVCDCENPT---VDLF-C 688
Query: 208 CPQCKER-KNYCEFR-GKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYE 265
CP+C R + C + G+T + V C++CRC GEV C CP EC +
Sbjct: 689 CPECDPRLSSQCLHQNGETLYNSGDTWVQNCQQCRC-LQGEVDCWPLPCPDVECEFSILP 747
Query: 266 PDQCCPICKNGP------------NCFAETAVI--PAGREVK-TDECTICHC 302
++CCP C P C E V+ +K ECT+C C
Sbjct: 748 ENECCPRCVTDPCQADTIRNDITKTCLDEMNVVRFTGSSWIKHGTECTLCQC 799
Score = 52.4 bits (124), Expect = 6e-07
Identities = 48/182 (26%), Positives = 68/182 (37%), Gaps = 23/182 (12%)
Query: 160 GFVYAIGEKFAPGPSACPCLCTE---EGPLCAQPECPRLHPRCIHVDTSQCCPQCKERKN 216
G Y E + G C CL E +C P+CP L +VD +CC +CK +
Sbjct: 278 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCP-LKSALAYVD-GKCCKECK---S 332
Query: 217 YCEFRGKTYQTLEEFVV----SPCERCRCEANGEVLCTVSACPQTECVD--PVYEPDQCC 270
C+F+G+TY E V C C+ L S CP +C + + CC
Sbjct: 333 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 392
Query: 271 PICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCT--------RHEC 322
+CK C + ++ +C C R E A C RH C
Sbjct: 393 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDGFRALR-EDNAYCEDIDECAEGRHYC 451
Query: 323 RQ 324
R+
Sbjct: 452 RE 453
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 52.4 bits (124), Expect = 6e-07
Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 17/132 (12%)
Query: 159 SGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLH--PRCIHVD-TSQCCPQCKERK 215
SG +Y + + G C C C + CP L+ P + V QCC C+ +
Sbjct: 276 SGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPK- 334
Query: 216 NYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTEC--VDPVYEPDQCCPIC 273
C + GK + + C CR G ++ CP C D + +QCC +C
Sbjct: 335 --CIYGGKVLAEGQRILTKSCRECR---GGVLVKITEMCPPLNCSEKDHILPENQCCRVC 389
Query: 274 K------NGPNC 279
+ GP C
Sbjct: 390 RGHNFCAEGPKC 401
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 178 CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKER-KNYCEFRG--KTYQTLEEFVVS 234
C C + C + C +P CCP+C R + C + K Y++ + + S
Sbjct: 610 CSCKDGKIFCRRTACDCQNPSA----DLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHS 665
Query: 235 PCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAE 282
C++CRC GEV C CP C +CCP C + P C A+
Sbjct: 666 -CQQCRC-LEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDP-CLAD 710
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 52.4 bits (124), Expect = 6e-07
Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 17/132 (12%)
Query: 159 SGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLH--PRCIHVD-TSQCCPQCKERK 215
SG +Y + + G C C C + CP L+ P + V QCC C+ +
Sbjct: 276 SGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPK- 334
Query: 216 NYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTEC--VDPVYEPDQCCPIC 273
C + GK + + C CR G ++ CP C D + +QCC +C
Sbjct: 335 --CIYGGKVLAEGQRILTKSCRECR---GGVLVKITEMCPPLNCSEKDHILPENQCCRVC 389
Query: 274 K------NGPNC 279
+ GP C
Sbjct: 390 RGHNFCAEGPKC 401
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 178 CLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKER-KNYCEFRG--KTYQTLEEFVVS 234
C C + C + C +P CCP+C R + C + K Y++ + + S
Sbjct: 657 CSCKDGKIFCRRTACDCQNPSA----DLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHS 712
Query: 235 PCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKNGPNCFAE 282
C++CRC GEV C CP C +CCP C + P C A+
Sbjct: 713 -CQQCRC-LEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDP-CLAD 757
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 52.0 bits (123), Expect = 7e-07
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 218 CEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQT-ECVDPVYEPDQCCPICKNG 276
C G+ Y + + +PC+ C C+ NG +LC C +C DPV P +CCP+C
Sbjct: 41 CTQNGQMYLNRDIWKPAPCQICVCD-NGAILCDKIECQDVLDCADPVTPPGECCPVCSQT 99
Query: 277 P 277
P
Sbjct: 100 P 100
>gi|30089980 chordin [Homo sapiens]
Length = 955
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/141 (27%), Positives = 52/141 (36%), Gaps = 32/141 (22%)
Query: 166 GEKFAPG--PSACPCLCTEEGPLCAQPECPRLHPRCIHVDTS--QCCPQCKERKNY---- 217
G ++AP P C C +C CP P C H + QCCP C E+++
Sbjct: 715 GARWAPNYDPLCSLCTCQRRTVICDPVVCPP--PSCPHPVQAPDQCCPVCPEKQDVRDLP 772
Query: 218 -----------CEFRG---------KTYQTLEEFVVSPCERCRCEAN-GEVLCTVSACPQ 256
C F G + + + F + C C C+ GEV C CP+
Sbjct: 773 GLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQCPR 832
Query: 257 TECVDPV-YEPDQCCPICKNG 276
C PV P CC C G
Sbjct: 833 LACAQPVRVNPTDCCKQCPVG 853
Score = 46.6 bits (109), Expect = 3e-05
Identities = 31/114 (27%), Positives = 38/114 (33%), Gaps = 27/114 (23%)
Query: 236 CERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKN----------------GPNC 279
C C C+ V+C CP C PV PDQCCP+C G C
Sbjct: 726 CSLCTCQRR-TVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGC 784
Query: 280 F---------AETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHECRQ 324
+ A T P +C +C C G E+ C R C Q
Sbjct: 785 YFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEK-VQCPRLACAQ 837
Score = 32.3 bits (72), Expect = 0.59
Identities = 24/75 (32%), Positives = 24/75 (32%), Gaps = 19/75 (25%)
Query: 218 CEFRGKTY--------QTLEEFVVSPCERCRCEAN---------GEVLCT--VSACPQTE 258
C F GK Y E F V C C CEA G V C CP
Sbjct: 51 CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110
Query: 259 CVDPVYEPDQCCPIC 273
C P P CC C
Sbjct: 111 CGQPRQLPGHCCQTC 125
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 48.1 bits (113), Expect = 1e-05
Identities = 43/149 (28%), Positives = 54/149 (36%), Gaps = 23/149 (15%)
Query: 122 ALAAAAQDAIGPELAPTPEPPEEYVYPDYRGKGCVD--------------ESGFV---YA 164
A AA QD G E P EE + P CV + GFV
Sbjct: 25 AAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCLQGGFVRGRVP 84
Query: 165 IGEKFAPGPSACPCLCTEEGP--LCAQPECPRLHPRCIH-VDTSQCCPQCKERKNYCEFR 221
G+ + + C C G C CP L P CI V + CPQC + C
Sbjct: 85 AGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPNCIEAVVVADSCPQCGQVG--CVHA 142
Query: 222 GKTYQTLEEFVVSPCERCRC-EANGEVLC 249
G Y + PC C C +A GE++C
Sbjct: 143 GHKYAAGHTVHLPPCRACHCPDAGGELIC 171
Score = 28.5 bits (62), Expect = 8.5
Identities = 11/26 (42%), Positives = 13/26 (50%), Gaps = 1/26 (3%)
Query: 249 CTVSACPQTE-CVDPVYEPDQCCPIC 273
CT CP E C++ EP CC C
Sbjct: 33 CTGVECPPLENCIEEALEPGACCATC 58
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 48.1 bits (113), Expect = 1e-05
Identities = 43/149 (28%), Positives = 54/149 (36%), Gaps = 23/149 (15%)
Query: 122 ALAAAAQDAIGPELAPTPEPPEEYVYPDYRGKGCVD--------------ESGFV---YA 164
A AA QD G E P EE + P CV + GFV
Sbjct: 25 AAAAPRQDCTGVECPPLENCIEEALEPGACCATCVQQGCACEGYQYYDCLQGGFVRGRVP 84
Query: 165 IGEKFAPGPSACPCLCTEEGP--LCAQPECPRLHPRCIH-VDTSQCCPQCKERKNYCEFR 221
G+ + + C C G C CP L P CI V + CPQC + C
Sbjct: 85 AGQSYFVDFGSTECSCPPGGGKISCQFMLCPELPPNCIEAVVVADSCPQCGQVG--CVHA 142
Query: 222 GKTYQTLEEFVVSPCERCRC-EANGEVLC 249
G Y + PC C C +A GE++C
Sbjct: 143 GHKYAAGHTVHLPPCRACHCPDAGGELIC 171
Score = 28.5 bits (62), Expect = 8.5
Identities = 11/26 (42%), Positives = 13/26 (50%), Gaps = 1/26 (3%)
Query: 249 CTVSACPQTE-CVDPVYEPDQCCPIC 273
CT CP E C++ EP CC C
Sbjct: 33 CTGVECPPLENCIEEALEPGACCATC 58
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 46.6 bits (109), Expect = 3e-05
Identities = 19/52 (36%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 222 GKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPIC 273
G+++ ++ C C C+ +G+V C V ACP C PV P CCP+C
Sbjct: 1420 GESHANNTKWKKDACTICECK-DGQVTCFVEACPPATCAVPVNIPGACCPVC 1470
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 46.6 bits (109), Expect = 3e-05
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Query: 219 EFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPICKN 275
+ RG + E ++ C C CE+ G+V C V CP C P CCP+C++
Sbjct: 1397 DVRGVPRKAEERWMKEDCTHCICES-GQVTCVVEICPPAPCPSPELVKGTCCPVCRD 1452
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 45.1 bits (105), Expect = 9e-05
Identities = 40/155 (25%), Positives = 51/155 (32%), Gaps = 31/155 (20%)
Query: 177 PCLCTEEGPLCAQPECPRLHPRC-------IHVDTSQCCPQCKERKNYCEFRGKTYQTLE 229
PC C E +C CP+ P C + CCP + R C + G Y
Sbjct: 5813 PC-CPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGA 5871
Query: 230 EFV-VSPCERCRC----EANGEVLCTVSACPQTEC---VDPVYEPDQCCPICKNGPNCFA 281
F PC C C + V C AC T C + QCC C
Sbjct: 5872 TFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCC------GECVQ 5925
Query: 282 ETAVIPAGREVK---------TDECTICHCTYEEG 307
+ P G+ V+ D CT+ C E G
Sbjct: 5926 TACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGG 5960
Score = 37.7 bits (86), Expect = 0.014
Identities = 26/109 (23%), Positives = 40/109 (36%), Gaps = 17/109 (15%)
Query: 154 GCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKE 213
GC D+ G Y +G + + C CT G CA + + C E
Sbjct: 1912 GCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAH--------------SLEACTCTYE 1957
Query: 214 RKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262
+ Y ++ Y T + + C C +NG ++ ACP T P
Sbjct: 1958 DRTY-SYQDVIYNTTDG--LGACLIAICGSNGTIIRKAVACPGTPATTP 2003
Score = 36.2 bits (82), Expect = 0.041
Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 18/83 (21%)
Query: 231 FVVSPCE-RCRCEANGEVLCTVSACPQTECVDP---------VYEPDQCCPICKNGPNCF 280
+VV C+ CR + +V C+VS P C P P Q CP C+
Sbjct: 1362 YVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECP-------CY 1414
Query: 281 AETAVIPAGREVKTDECTICHCT 303
A V+ G EV DE +C CT
Sbjct: 1415 AHGTVLAPG-EVVHDEGAVCSCT 1436
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 45.1 bits (105), Expect = 9e-05
Identities = 40/155 (25%), Positives = 51/155 (32%), Gaps = 31/155 (20%)
Query: 177 PCLCTEEGPLCAQPECPRLHPRC-------IHVDTSQCCPQCKERKNYCEFRGKTYQTLE 229
PC C E +C CP+ P C + CCP + R C + G Y
Sbjct: 5479 PC-CPETVCVCNTTTCPQSLPVCPPGQESICTQEEGDCCPTFRCRPQLCSYNGTFYGVGA 5537
Query: 230 EFV-VSPCERCRC----EANGEVLCTVSACPQTEC---VDPVYEPDQCCPICKNGPNCFA 281
F PC C C + V C AC T C + QCC C
Sbjct: 5538 TFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCC------GECVQ 5591
Query: 282 ETAVIPAGREVK---------TDECTICHCTYEEG 307
+ P G+ V+ D CT+ C E G
Sbjct: 5592 TACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGG 5626
Score = 37.7 bits (86), Expect = 0.014
Identities = 26/109 (23%), Positives = 40/109 (36%), Gaps = 17/109 (15%)
Query: 154 GCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQCKE 213
GC D+ G Y +G + + C CT G CA + + C E
Sbjct: 1222 GCYDKDGNYYDVGARVPTAENCQSCNCTPSGIQCAH--------------SLEACTCTYE 1267
Query: 214 RKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262
+ Y ++ Y T + + C C +NG ++ ACP T P
Sbjct: 1268 DRTY-SYQDVIYNTTDG--LGACLIAICGSNGTIIRKAVACPGTPATTP 1313
Score = 36.2 bits (82), Expect = 0.041
Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 18/83 (21%)
Query: 231 FVVSPCE-RCRCEANGEVLCTVSACPQTECVDP---------VYEPDQCCPICKNGPNCF 280
+VV C+ CR + +V C+VS P C P P Q CP C+
Sbjct: 706 YVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECP-------CY 758
Query: 281 AETAVIPAGREVKTDECTICHCT 303
A V+ G EV DE +C CT
Sbjct: 759 AHGTVLAPG-EVVHDEGAVCSCT 780
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 44.7 bits (104), Expect = 1e-04
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Query: 214 RKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPIC 273
+K +C +G T + PC C C ++G VLC + C C V +CCP+C
Sbjct: 99 KKGHCLVKGITMYNKAVWSPEPCTTCLC-SDGRVLCDETMCHPQRCPQTVIPEGECCPVC 157
Score = 32.7 bits (73), Expect = 0.45
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 3/61 (4%)
Query: 173 PSACP-CLCTEEGPLCAQPEC-PRLHPRCIHVDTSQCCPQCKERKNYCEFRGKTYQTLEE 230
P C CLC++ LC + C P+ P+ + + +CCP C +Y G E
Sbjct: 118 PEPCTTCLCSDGRVLCDETMCHPQRCPQTV-IPEGECCPVCSATVSYSLLSGIALNDRNE 176
Query: 231 F 231
F
Sbjct: 177 F 177
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 44.3 bits (103), Expect = 1e-04
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 1/60 (1%)
Query: 214 RKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDPVYEPDQCCPIC 273
R C G Y+ EE+ V C C C+ N +C +CP C + +CCP C
Sbjct: 314 RPPLCYHNGVQYRNNEEWTVDSCTECHCQ-NSVTICKKVSCPIMPCSNATVPDGECCPRC 372
Score = 28.9 bits (63), Expect = 6.5
Identities = 11/38 (28%), Positives = 16/38 (42%)
Query: 174 SACPCLCTEEGPLCAQPECPRLHPRCIHVDTSQCCPQC 211
S C C +C + CP + V +CCP+C
Sbjct: 335 SCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRC 372
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,827,955
Number of Sequences: 37866
Number of extensions: 1005359
Number of successful extensions: 4772
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 244
Number of HSP's that attempted gapping in prelim test: 3874
Number of HSP's gapped (non-prelim): 770
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.