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Search of human proteins with 38348356
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38348356 testis expressed 9 [Homo sapiens]
(391 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38348356 testis expressed 9 [Homo sapiens] 764 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 74 2e-13
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 71 1e-12
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 71 1e-12
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 70 3e-12
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 69 7e-12
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 66 6e-11
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 65 1e-10
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ... 65 1e-10
gi|4503593 epidermal growth factor receptor pathway substrate 15... 59 6e-09
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 59 6e-09
gi|156104908 myosin heavy chain 6 [Homo sapiens] 59 6e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 59 8e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 59 8e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 59 8e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 59 8e-09
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 59 1e-08
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 58 2e-08
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 58 2e-08
gi|71061468 centromere protein E [Homo sapiens] 57 3e-08
gi|229577185 epidermal growth factor receptor pathway substrate ... 56 5e-08
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 54 2e-07
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens] 54 2e-07
gi|45446749 kinesin family member 5A [Homo sapiens] 54 2e-07
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 54 3e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 54 3e-07
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 53 4e-07
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 53 4e-07
gi|38569484 kinesin family member 21A [Homo sapiens] 53 4e-07
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 53 4e-07
>gi|38348356 testis expressed 9 [Homo sapiens]
Length = 391
Score = 764 bits (1974), Expect = 0.0
Identities = 391/391 (100%), Positives = 391/391 (100%)
Query: 1 MAGRSLCLTRSSVPGTPFPPPVQQPSTPGPDLLALEEEYKRLNAELQAKTADVVQQAKEI 60
MAGRSLCLTRSSVPGTPFPPPVQQPSTPGPDLLALEEEYKRLNAELQAKTADVVQQAKEI
Sbjct: 1 MAGRSLCLTRSSVPGTPFPPPVQQPSTPGPDLLALEEEYKRLNAELQAKTADVVQQAKEI 60
Query: 61 IRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKL 120
IRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKL
Sbjct: 61 IRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKL 120
Query: 121 HSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDI 180
HSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDI
Sbjct: 121 HSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDI 180
Query: 181 FSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQ 240
FSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQ
Sbjct: 181 FSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQ 240
Query: 241 RTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLN 300
RTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLN
Sbjct: 241 RTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLN 300
Query: 301 RALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLID 360
RALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLID
Sbjct: 301 RALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLID 360
Query: 361 VLKRQKMHIEAAKMLSFTEEEFMKALEWGNS 391
VLKRQKMHIEAAKMLSFTEEEFMKALEWGNS
Sbjct: 361 VLKRQKMHIEAAKMLSFTEEEFMKALEWGNS 391
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 73.9 bits (180), Expect = 2e-13
Identities = 79/356 (22%), Positives = 153/356 (42%), Gaps = 58/356 (16%)
Query: 37 EEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGI 96
EE + +N+EL AK ++ + + RD ++ + + E+ +
Sbjct: 931 EEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENK-----------V 979
Query: 97 VHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFS 156
+L E +NI + K + L A++ QT DD+ + ED
Sbjct: 980 KNLSEEMTALEENISKLTKEKKSLQEAHQ---------------QTLDDLQVEED----- 1019
Query: 157 LAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLH---------VMQEE 207
+ KI +LE++ DD+ + + A + K KL +M E
Sbjct: 1020 KVNGLIKINAKLEQQ-----TDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLE 1074
Query: 208 LDNVVCE--CNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYD 265
D E KKE E+ L++++ + + ++ Q+ I Q+++E+ + E +
Sbjct: 1075 NDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRA 1134
Query: 266 GLQQQLSSVERELEN-KRRLQKQAASSQSATEV---------RLNRALEEAE-KYKLELS 314
+++Q S + RELE RL++ + ++ + E+ ++ R LEEA +++ +
Sbjct: 1135 KIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1194
Query: 315 KLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
LR+ D E ++I+ L+ +KLEK+K EL + I+ L + K +IE
Sbjct: 1195 TLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIE 1250
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/303 (19%), Positives = 135/303 (44%), Gaps = 36/303 (11%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEI-IRDRQEVRSRPVSTQMKSCDDEDDYSLRG 89
D L E+ K A ++ + ++++ +E+ + Q R+R +S Q + D D L
Sbjct: 1663 DALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQ-ELLDASDRVQL-- 1719
Query: 90 LLPSEGIVHLHSETKPKTK----NIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADD 145
L S+ ++++ K + + N +Q ++ K +K + + +++ D
Sbjct: 1720 -LHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQD 1778
Query: 146 VAIPEDFSDFSLAKTISKIEGQLEE-EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVM 204
+ + +L +T+ ++ +L+E E L + G E ++R L+ +L V
Sbjct: 1779 TSAHLERMKKNLEQTVKDLQHRLDEAEQLA-----LKGGKKQIQKLENRVRELENELDVE 1833
Query: 205 QEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKY 264
Q+ + +K E +++ + Q + ++ +R Q ++ Q++V+ YK EEA ++
Sbjct: 1834 QKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ- 1892
Query: 265 DGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIA 324
+L RR+Q + L A E A+ + +++KLR ++D+
Sbjct: 1893 ---------ANTQLSRCRRVQHE-----------LEEAAERADIAESQVNKLRAKSRDVG 1932
Query: 325 NEE 327
+++
Sbjct: 1933 SQK 1935
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/204 (18%), Positives = 94/204 (46%), Gaps = 12/204 (5%)
Query: 190 TEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQ 249
+EA+ + L+ K+ + +E +++ + + + + + + + + + + + + +
Sbjct: 870 SEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTER 929
Query: 250 VEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKY 309
+E+ + + E K L+ + SS++R++++ + + ATE ++ EE
Sbjct: 930 LEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTAL 989
Query: 310 KLELSKLRQNNKDIANEEHKKIEVLKSE----------NKKLEKQKGELMIGFKKQLKLI 359
+ +SKL + K + + ++ L+ E N KLE+Q +L +++ KL
Sbjct: 990 EENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLR 1049
Query: 360 DVLKRQKMHIEAAKMLSFTEEEFM 383
L+R K +E L ++E M
Sbjct: 1050 ADLERAKRKLEGD--LKMSQESIM 1071
Score = 42.0 bits (97), Expect = 0.001
Identities = 63/338 (18%), Positives = 144/338 (42%), Gaps = 50/338 (14%)
Query: 32 LLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQ------------EVRSRPVSTQMKSC 79
+L ++ E ++ +EL K + ++ +++ R+ Q E+RSR + ++K
Sbjct: 1562 ILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKK 1621
Query: 80 DDEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSA----NKGRKTNSSVKL 135
+ D +E + L + + + VQ +L + + ++N +K
Sbjct: 1622 MEGD--------LNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKE 1673
Query: 136 KYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIR 195
+ + V+ + + + E+ + +A ++ +L E+ L + D + S + +
Sbjct: 1674 QLAIVERRNGLLL-EELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKK 1732
Query: 196 FLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTI--------NMQQ 247
L+A + Q E++N + E E++ + + E+ ++Q T N++Q
Sbjct: 1733 KLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQ 1792
Query: 248 SQVEKYKTLFEEANKKYDGLQQQLSSVE---RELENKRRLQKQAASSQSATEVRLNRALE 304
+ + L E G ++Q+ +E RELEN+ ++++ + AL+
Sbjct: 1793 TVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGA----------EALK 1842
Query: 305 EAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLE 342
A KY+ ++ ++ A E+HK I L+ KL+
Sbjct: 1843 GAHKYERKVKEMTYQ----AEEDHKNILRLQDLVDKLQ 1876
Score = 38.1 bits (87), Expect = 0.014
Identities = 72/387 (18%), Positives = 156/387 (40%), Gaps = 41/387 (10%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSR--PVSTQMKSCDDEDDYSLR 88
DL +++ A L+ K AD V + E I + Q V+ + +++K D+ ++
Sbjct: 1181 DLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIE 1240
Query: 89 GLLPSEGIVHLHSET-KPKTKNIDPVNKVQNKL-HSAN--KGRKTNSSVKLKYSDVQTAD 144
L S+ + T + + I ++ Q +L H N K R + +L + V+ +
Sbjct: 1241 ALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHR-VEEKE 1299
Query: 145 DVAIPEDFSDFSLAKTISKIEGQLEEEG-------------------LPEYIDDIFSGVS 185
+ S +L + + +++ Q+EEE L E ++
Sbjct: 1300 SLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEE-----E 1354
Query: 186 NDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINM 245
+ E Q KA V Q + ++ +E++ K ++ ++ T N
Sbjct: 1355 QEAKAELQRALSKANSEVAQWRT-KYETDAIQRTEELEEAKKKLAQRLQEAEENTETANS 1413
Query: 246 QQSQVEKYKTLF----EEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNR 301
+ + +EK K E+ + + ++++++ N ++ + ++ L
Sbjct: 1414 KCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEA 1473
Query: 302 ALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDV 361
A +E+ EL K+R +++ ++ +E L+ ENK L+++ +L + K +
Sbjct: 1474 AQKESRSLSTELFKMRNAYEEVVDQ----LETLRRENKNLQEEISDLTEQIAETGKNLQE 1529
Query: 362 LKRQKMHIEAAKM-LSFTEEEFMKALE 387
++ K +E K L EE +LE
Sbjct: 1530 AEKTKKLVEQEKSDLQVALEEVEGSLE 1556
Score = 36.6 bits (83), Expect = 0.040
Identities = 50/234 (21%), Positives = 108/234 (46%), Gaps = 27/234 (11%)
Query: 153 SDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVV 212
S L + ++ +LEEE E ++ + N E + LK + ++ L V
Sbjct: 915 SKILLEAKVKELTERLEEE--EEMNSELVAKKRN---LEDKCSSLKRDIDDLELTLTKVE 969
Query: 213 CECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKK-YDGLQQQL 271
E + E++++NL ++ EE+ S++ K K +EA+++ D LQ +
Sbjct: 970 KEKHATENKVKNLSEEMTALEENI-----------SKLTKEKKSLQEAHQQTLDDLQVEE 1018
Query: 272 SSVERELENKRRLQKQAASSQSA--TEVRLNRALEEAE-KYKLELSKLRQNNKDIANEEH 328
V ++ +L++Q + + E +L LE A+ K + +L +++ D+ N++
Sbjct: 1019 DKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQ 1078
Query: 329 KKIEVLKSENKKLEKQKGEL------MIGFKKQLKLIDV-LKRQKMHIEAAKML 375
+ E LK + +L + + ++ + F+K++K + ++ + IEA L
Sbjct: 1079 QIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTL 1132
Score = 33.1 bits (74), Expect = 0.44
Identities = 49/225 (21%), Positives = 92/225 (40%), Gaps = 25/225 (11%)
Query: 123 ANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKI-EGQLEEEGLPEYIDDIF 181
A G+ + K K Q D+ + + + SL SKI QLE + +D
Sbjct: 1521 AETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDR-- 1578
Query: 182 SGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECN-------KKEDEIQNLKSQVKNFEE 234
+ D E R + +Q LD + N K E ++ ++ Q+ +
Sbjct: 1579 KVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNR 1638
Query: 235 DFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVER-------ELENKRRLQKQ 287
Q+ + Q Q++ + ++A + + L++QL+ VER ELE + +Q
Sbjct: 1639 QMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQ 1698
Query: 288 AASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIE 332
++ +E L L+ +++ +L L N + N + KK+E
Sbjct: 1699 TERTRRLSEQEL---LDASDRVQL----LHSQNTSLINTK-KKLE 1735
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 71.2 bits (173), Expect = 1e-12
Identities = 82/392 (20%), Positives = 178/392 (45%), Gaps = 55/392 (14%)
Query: 32 LLALEEEYKRLNAELQAKT---ADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLR 88
++ L +E L ++QA+ AD ++ ++I+ + ++ ++ + + +DE++ +
Sbjct: 883 MVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAK-IKEVTERAEDEEEINAE 941
Query: 89 GLLPSEGIVHLHSETKPKTKNID-PVNKVQNKLHSANKGRK----------------TNS 131
+ SE K +++ + KV+ + H+ K T
Sbjct: 942 LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 1001
Query: 132 SVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSND---- 187
L+ + QT DD+ ED T++K + +LE++ +DD+ + +
Sbjct: 1002 KKALQEAHQQTLDDLQAEED-----KVNTLTKAKIKLEQQ-----VDDLEGSLEQEKKLR 1051
Query: 188 IGTEAQIRFLKAKLHVMQEELDNVVCE-------CNKKEDEIQNLKSQVKNFEEDFMRQQ 240
+ E R L+ L + QE + ++ E KKE EI NL+S++++ + ++ Q
Sbjct: 1052 MDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQ 1111
Query: 241 RTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELEN-KRRLQKQAASSQSATEV-- 297
+ I Q+++E+ + E ++Q S + RELE RL++ ++ + E+
Sbjct: 1112 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1171
Query: 298 -------RLNRALEEAE-KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELM 349
++ R LEEA +++ + LR+ + D E ++I+ L+ +KLEK+K E+
Sbjct: 1172 KREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1231
Query: 350 IGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEE 381
+ ++ + + K ++E KM E++
Sbjct: 1232 MEIDDLASNVETVSKAKGNLE--KMCRTLEDQ 1261
Score = 45.4 bits (106), Expect = 9e-05
Identities = 77/397 (19%), Positives = 152/397 (38%), Gaps = 66/397 (16%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSR--------PVSTQMKSCDDEDDYS 86
+EE + + AE +A A +Q ++ R+ +E+ R +M + +
Sbjct: 1121 IEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQK 1179
Query: 87 LRGLLPSEGIVHLHSETKPKTKNIDPV----NKVQNKLHSANKGRKTNSSVKLKYSD--- 139
+R L + H + + K+ D V ++ N K K S +K++ D
Sbjct: 1180 MRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1239
Query: 140 -VQTADDV---------AIPEDFSDFS--------LAKTISKIEGQLEEEG--LPEYIDD 179
V+T + + S+ L ++ G+L+ E +D+
Sbjct: 1240 NVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDE 1299
Query: 180 IFSGVSN-DIGTEA---QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEED 235
+ VS G +A QI LK +L + + + + L+ Q + +E
Sbjct: 1300 KEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQES 1359
Query: 236 FMRQQRTINMQQSQVEKYKTLFE-----------EANKKYDGLQQQLSSVERELE----- 279
QR ++ ++V +++T +E EA KK L Q+L + E +E
Sbjct: 1360 KAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK---LAQRLQAAEEHVEAVNAK 1416
Query: 280 ------NKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEV 333
K+RLQ + E R N A +K + K+ K E H ++E
Sbjct: 1417 CASLEKTKQRLQNEVEDLMLDVE-RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475
Query: 334 LKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
+ E + L + ++ +++ L ++ LKR+ +++
Sbjct: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512
Score = 40.4 bits (93), Expect = 0.003
Identities = 51/271 (18%), Positives = 116/271 (42%), Gaps = 22/271 (8%)
Query: 41 RLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLH 100
R +L+ + A V ++A + + +E+R+ T+ E + L SE + LH
Sbjct: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL----LDASERVQLLH 1723
Query: 101 SET----KPKTKNIDPVNKVQNKL--------HSANKGRKTNSSVKLKYSDVQTADDVAI 148
++ K K ++++Q ++ ++ K +K + + +++ D +
Sbjct: 1724 TQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1783
Query: 149 PEDFSDFSLAKTISKIEGQLEE-EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEE 207
+ ++ +T+ ++ +L+E E L + G EA++R L+ ++ Q+
Sbjct: 1784 HLERMKKNMEQTVKDLQLRLDEAEQLA-----LKGGKKQIQKLEARVRELEGEVESEQKR 1838
Query: 208 LDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGL 267
V K E ++ L Q + ++ +R Q ++ Q++V+ YK EEA ++ +
Sbjct: 1839 NAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTN 1898
Query: 268 QQQLSSVERELENKRRLQKQAASSQSATEVR 298
+ ++ ELE A S + V+
Sbjct: 1899 LAKFRKLQHELEEAEERADIAESQVNKLRVK 1929
Score = 33.5 bits (75), Expect = 0.34
Identities = 46/224 (20%), Positives = 82/224 (36%), Gaps = 47/224 (20%)
Query: 205 QEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVE------------- 251
++E+ + E K +DE+ +++ K EE + + N Q QV+
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERC 911
Query: 252 ------------KYKTLFE----------EANKKYDGLQQQLSSVERELENKRRLQKQAA 289
K K + E E K L+ + S +++++++ +
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 290 SSQSATEVRLNRALEE----------AEKYKLELSKLRQNNKDIANEEHKKIEVLKSENK 339
+ ATE ++ EE K K L + Q D E K+ L
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1031
Query: 340 KLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFM 383
KLE+Q +L +++ KL L+R K +E L +E M
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD--LKLAQESIM 1073
Score = 32.3 bits (72), Expect = 0.75
Identities = 22/149 (14%), Positives = 60/149 (40%), Gaps = 4/149 (2%)
Query: 199 AKLHVMQEELDNVVCE----CNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYK 254
A L Q D ++ E C + E++ + + ++ + + + Q+E K
Sbjct: 1446 AALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLK 1505
Query: 255 TLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELS 314
+ ++ L +Q++ + + +++KQ + + L A E + ++
Sbjct: 1506 RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKIL 1565
Query: 315 KLRQNNKDIANEEHKKIEVLKSENKKLEK 343
+++ + +E +KI E +L++
Sbjct: 1566 RIQLELNQVKSEVDRKIAEKDEEIDQLKR 1594
Score = 30.8 bits (68), Expect = 2.2
Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 11/140 (7%)
Query: 217 KKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVER 276
K E ++ ++ Q+ + R Q ++ + ++A + + L++QL+ VER
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 277 -------ELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNK----DIAN 325
E+E R +Q S+ E L A E + + + L K DI+
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 326 EEHKKIEVLKSENKKLEKQK 345
+ + ++L+ EK K
Sbjct: 1743 MQGEMEDILQEARNAEEKAK 1762
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 71.2 bits (173), Expect = 1e-12
Identities = 82/392 (20%), Positives = 178/392 (45%), Gaps = 55/392 (14%)
Query: 32 LLALEEEYKRLNAELQAKT---ADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLR 88
++ L +E L ++QA+ AD ++ ++I+ + ++ ++ + + +DE++ +
Sbjct: 883 MVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAK-IKEVTERAEDEEEINAE 941
Query: 89 GLLPSEGIVHLHSETKPKTKNID-PVNKVQNKLHSANKGRK----------------TNS 131
+ SE K +++ + KV+ + H+ K T
Sbjct: 942 LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 1001
Query: 132 SVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSND---- 187
L+ + QT DD+ ED T++K + +LE++ +DD+ + +
Sbjct: 1002 KKALQEAHQQTLDDLQAEED-----KVNTLTKAKIKLEQQ-----VDDLEGSLEQEKKLR 1051
Query: 188 IGTEAQIRFLKAKLHVMQEELDNVVCE-------CNKKEDEIQNLKSQVKNFEEDFMRQQ 240
+ E R L+ L + QE + ++ E KKE EI NL+S++++ + ++ Q
Sbjct: 1052 MDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQ 1111
Query: 241 RTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELEN-KRRLQKQAASSQSATEV-- 297
+ I Q+++E+ + E ++Q S + RELE RL++ ++ + E+
Sbjct: 1112 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1171
Query: 298 -------RLNRALEEAE-KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELM 349
++ R LEEA +++ + LR+ + D E ++I+ L+ +KLEK+K E+
Sbjct: 1172 KREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1231
Query: 350 IGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEE 381
+ ++ + + K ++E KM E++
Sbjct: 1232 MEIDDLASNVETVSKAKGNLE--KMCRTLEDQ 1261
Score = 45.4 bits (106), Expect = 9e-05
Identities = 77/397 (19%), Positives = 152/397 (38%), Gaps = 66/397 (16%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSR--------PVSTQMKSCDDEDDYS 86
+EE + + AE +A A +Q ++ R+ +E+ R +M + +
Sbjct: 1121 IEELEEEIEAE-RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQK 1179
Query: 87 LRGLLPSEGIVHLHSETKPKTKNIDPV----NKVQNKLHSANKGRKTNSSVKLKYSD--- 139
+R L + H + + K+ D V ++ N K K S +K++ D
Sbjct: 1180 MRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1239
Query: 140 -VQTADDV---------AIPEDFSDFS--------LAKTISKIEGQLEEEG--LPEYIDD 179
V+T + + S+ L ++ G+L+ E +D+
Sbjct: 1240 NVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDE 1299
Query: 180 IFSGVSN-DIGTEA---QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEED 235
+ VS G +A QI LK +L + + + + L+ Q + +E
Sbjct: 1300 KEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQES 1359
Query: 236 FMRQQRTINMQQSQVEKYKTLFE-----------EANKKYDGLQQQLSSVERELE----- 279
QR ++ ++V +++T +E EA KK L Q+L + E +E
Sbjct: 1360 KAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK---LAQRLQAAEEHVEAVNAK 1416
Query: 280 ------NKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEV 333
K+RLQ + E R N A +K + K+ K E H ++E
Sbjct: 1417 CASLEKTKQRLQNEVEDLMLDVE-RTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1475
Query: 334 LKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
+ E + L + ++ +++ L ++ LKR+ +++
Sbjct: 1476 SQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512
Score = 40.4 bits (93), Expect = 0.003
Identities = 51/271 (18%), Positives = 116/271 (42%), Gaps = 22/271 (8%)
Query: 41 RLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLH 100
R +L+ + A V ++A + + +E+R+ T+ E + L SE + LH
Sbjct: 1668 RSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL----LDASERVQLLH 1723
Query: 101 SET----KPKTKNIDPVNKVQNKL--------HSANKGRKTNSSVKLKYSDVQTADDVAI 148
++ K K ++++Q ++ ++ K +K + + +++ D +
Sbjct: 1724 TQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1783
Query: 149 PEDFSDFSLAKTISKIEGQLEE-EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEE 207
+ ++ +T+ ++ +L+E E L + G EA++R L+ ++ Q+
Sbjct: 1784 HLERMKKNMEQTVKDLQLRLDEAEQLA-----LKGGKKQIQKLEARVRELEGEVESEQKR 1838
Query: 208 LDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGL 267
V K E ++ L Q + ++ +R Q ++ Q++V+ YK EEA ++ +
Sbjct: 1839 NAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTN 1898
Query: 268 QQQLSSVERELENKRRLQKQAASSQSATEVR 298
+ ++ ELE A S + V+
Sbjct: 1899 LAKFRKLQHELEEAEERADIAESQVNKLRVK 1929
Score = 33.5 bits (75), Expect = 0.34
Identities = 46/224 (20%), Positives = 82/224 (36%), Gaps = 47/224 (20%)
Query: 205 QEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVE------------- 251
++E+ + E K +DE+ +++ K EE + + N Q QV+
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERC 911
Query: 252 ------------KYKTLFE----------EANKKYDGLQQQLSSVERELENKRRLQKQAA 289
K K + E E K L+ + S +++++++ +
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 290 SSQSATEVRLNRALEE----------AEKYKLELSKLRQNNKDIANEEHKKIEVLKSENK 339
+ ATE ++ EE K K L + Q D E K+ L
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1031
Query: 340 KLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFM 383
KLE+Q +L +++ KL L+R K +E L +E M
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD--LKLAQESIM 1073
Score = 32.3 bits (72), Expect = 0.75
Identities = 22/149 (14%), Positives = 60/149 (40%), Gaps = 4/149 (2%)
Query: 199 AKLHVMQEELDNVVCE----CNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYK 254
A L Q D ++ E C + E++ + + ++ + + + Q+E K
Sbjct: 1446 AALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLK 1505
Query: 255 TLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELS 314
+ ++ L +Q++ + + +++KQ + + L A E + ++
Sbjct: 1506 RENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKIL 1565
Query: 315 KLRQNNKDIANEEHKKIEVLKSENKKLEK 343
+++ + +E +KI E +L++
Sbjct: 1566 RIQLELNQVKSEVDRKIAEKDEEIDQLKR 1594
Score = 30.8 bits (68), Expect = 2.2
Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 11/140 (7%)
Query: 217 KKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVER 276
K E ++ ++ Q+ + R Q ++ + ++A + + L++QL+ VER
Sbjct: 1623 KMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVER 1682
Query: 277 -------ELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNK----DIAN 325
E+E R +Q S+ E L A E + + + L K DI+
Sbjct: 1683 RANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQ 1742
Query: 326 EEHKKIEVLKSENKKLEKQK 345
+ + ++L+ EK K
Sbjct: 1743 MQGEMEDILQEARNAEEKAK 1762
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 70.1 bits (170), Expect = 3e-12
Identities = 80/368 (21%), Positives = 168/368 (45%), Gaps = 54/368 (14%)
Query: 37 EEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGI 96
EE + +N+EL A+ + + E+ ++ ++ + V ++ + E
Sbjct: 939 EEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEH------------- 985
Query: 97 VHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFS 156
+ K T+ ++ +N+ +KL+ A K ++ + QT DD+ + E+ S
Sbjct: 986 -----KVKNLTEEVEFLNEDISKLNRAAK--------VVQEAHQQTLDDLHMEEEKLS-S 1031
Query: 157 LAKTISKIEGQLEE-EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVC-- 213
L+K K+E Q++E EG E + E ++ L+ L + +E ++N+
Sbjct: 1032 LSKANLKLEQQVDELEGALE------QERKARMNCERELHKLEGNLKLNRESMENLESSQ 1085
Query: 214 -----ECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQ 268
E KKE E+ + S+V+N + + Q+T+ Q+Q++ K E ++
Sbjct: 1086 RHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKME 1145
Query: 269 QQLSSVERELEN-KRRLQKQAASSQSATEV---------RLNRALEEAE-KYKLELSKLR 317
++ + + ++L + RL++ SS + E+ +L+R +EEA ++ + L+
Sbjct: 1146 RERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLK 1205
Query: 318 QNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSF 377
+ + D E ++E L+ +KLEK K +L + L ++ + R K + E K+ +
Sbjct: 1206 KRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAE--KLCTL 1263
Query: 378 TEEEFMKA 385
EE +A
Sbjct: 1264 YEERLHEA 1271
Score = 63.9 bits (154), Expect = 2e-10
Identities = 85/405 (20%), Positives = 171/405 (42%), Gaps = 57/405 (14%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDY--------- 85
+EEE + L+ + + +I+ + E+ + K + +++
Sbjct: 1545 IEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQC 1604
Query: 86 ---SLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANK----GRKTNSSVKLKYS 138
SL+ L SE + T+ K K + +N+++ +L AN+ K+ ++++
Sbjct: 1605 TIDSLQSSLDSEAKSRIEV-TRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIK 1663
Query: 139 DVQTADD------------VAIPE--------DFSDFSLAKTISKIEGQLEEEGLPEYID 178
D+Q D VA+ E + D + ++ +L EE L E +
Sbjct: 1664 DLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATE 1723
Query: 179 DIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMR 238
I + + +Q + L+A + MQ+E + VV EC E++ + + N E+ +
Sbjct: 1724 RINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKK 1783
Query: 239 QQRTI--------NMQQSQVEKYKTLFEEANKKYDGLQQQLSSVE---RELENKRRLQKQ 287
+Q TI NM+Q+ + K L E G ++Q+ +E RELE + + +
Sbjct: 1784 KQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIR 1843
Query: 288 AASSQSATEVRLNRALEE----AEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEK 343
++ RL R ++E AE+ K LS+++ ++ K++ K + + E
Sbjct: 1844 RSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQ----MDKLQLKVQNYKQQVEVAET 1899
Query: 344 QKGELMIGFKKQL-KLIDVLKRQKMHIEAAKMLSFTEEEFMKALE 387
Q + + +KKQ +L +V +R ++ L EF K ++
Sbjct: 1900 QANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQ 1944
Score = 46.2 bits (108), Expect = 5e-05
Identities = 44/195 (22%), Positives = 89/195 (45%), Gaps = 18/195 (9%)
Query: 204 MQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLF----EE 259
+QEE+ N+ + + + ++ K EE+ Q T+ + +E+ ++ E
Sbjct: 1517 LQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLE 1576
Query: 260 ANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQN 319
+ L+++LS + E+EN RR Q+ S L +L+ K ++E+++L++
Sbjct: 1577 LLEAKAELERKLSEKDEEIENFRRKQQCTIDS-------LQSSLDSEAKSRIEVTRLKKK 1629
Query: 320 NKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKK-QLKLIDV------LKRQKMHIEAA 372
++ NE ++ + + K G+L I K Q++L D LK Q E
Sbjct: 1630 MEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERR 1689
Query: 373 KMLSFTEEEFMKALE 387
L +E E +++L+
Sbjct: 1690 NSLLQSELEDLRSLQ 1704
Score = 44.7 bits (104), Expect = 1e-04
Identities = 57/233 (24%), Positives = 104/233 (44%), Gaps = 38/233 (16%)
Query: 162 SKIEGQLEEEGLPEYIDDIFSGVSNDIGTE--AQIRFLKAKLHVMQEELDNVVCECNKKE 219
SKI+ + + L E +++ +I +E A+ R L+ + +++E+D++ K E
Sbjct: 923 SKIQLEARVKELSERVEE-----EEEINSELTARGRKLEDECFELKKEIDDLETMLVKSE 977
Query: 220 DEIQNLKSQVKNFEED--FMRQ----------------QRTINMQQSQVEKYKTLFEEAN 261
E + + +VKN E+ F+ + Q+T++ + EK +L +AN
Sbjct: 978 KEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSL-SKAN 1036
Query: 262 KKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNK 321
K L+QQ+ +E LE +R+ + E L E E L + +
Sbjct: 1037 LK---LEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMEN-------LESSQR 1086
Query: 322 DIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDV-LKRQKMHIEAAK 373
+A E KK L N K+E +KG L+ +K +K + +K K +EA +
Sbjct: 1087 HLAEELRKKELELSQMNSKVENEKG-LVAQLQKTVKELQTQIKDLKEKLEAER 1138
Score = 41.2 bits (95), Expect = 0.002
Identities = 75/358 (20%), Positives = 143/358 (39%), Gaps = 56/358 (15%)
Query: 35 LEEEYKRLNAELQA--KTADVVQQAKEIIRDRQEVRSRPVSTQMKS---CDDEDDYSLRG 89
L EE + LN ++ + A VVQ+A + D + +S+ K+ + + D L G
Sbjct: 990 LTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVD-ELEG 1048
Query: 90 LLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTN--SSVKLKYSDVQTADDVA 147
L E ++ E +LH K N S L+ S A+++
Sbjct: 1049 ALEQERKARMNCE---------------RELHKLEGNLKLNRESMENLESSQRHLAEELR 1093
Query: 148 IPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEE 207
E L++ SK+E E+GL + + + QI+ LK KL +
Sbjct: 1094 KKE----LELSQMNSKVEN---EKGLVAQLQKTVKEL------QTQIKDLKEKLEAERTT 1140
Query: 208 LDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGL 267
+ E ++ +L +++ + Q Q+++ +K EEA ++
Sbjct: 1141 RAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETT 1200
Query: 268 Q--------QQLSSVERELEN----KRRLQKQAASSQSATEVRLNRALEEAEKYKLELSK 315
L+ +E ++EN K++L+K + Q + L R +E+ + K K
Sbjct: 1201 SASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTR-VEQMTRAKANAEK 1259
Query: 316 LRQNNKDIANEEHKKIEV-------LKSENKKLEKQKGELMIGFKKQLKLIDVLKRQK 366
L ++ +E K++ L ++ KL + GE + +++ LI+ L R+K
Sbjct: 1260 LCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREK 1317
Score = 36.6 bits (83), Expect = 0.040
Identities = 55/286 (19%), Positives = 120/286 (41%), Gaps = 32/286 (11%)
Query: 98 HLHSETKPKTKNIDPVN-KVQNKLHSANKGRKTNSSVKLKYSDV------QTADDVAIPE 150
HL E + K + +N KV+N+ + +KT ++ + D+ + +
Sbjct: 1087 HLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMER 1146
Query: 151 DFSDFSLAKTISKIEGQLEEEG--------LPEYIDDIFSGVSNDIGTEAQIRFLKAKLH 202
+ +D L + ++ + +LEE G + + + F + D+ EA + F
Sbjct: 1147 ERAD--LTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDM-EEATLHFETTSAS 1203
Query: 203 VMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANK 262
+ + D++ + E +++NL+ + E+D Q ++ ++VE+ A K
Sbjct: 1204 LKKRHADSLA----ELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEK 1259
Query: 263 KYDGLQQQLSSVERELENKRRLQKQAASSQS---ATEVRLNRALEEAEKYKLELSKLRQN 319
+++L +L+ +L A+ ++ + R LEE E +LS+ + N
Sbjct: 1260 LCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSN 1319
Query: 320 NKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQ 365
++IE L+ + +K K + L +K + D+L+ Q
Sbjct: 1320 FT-------RQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQ 1358
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 68.9 bits (167), Expect = 7e-12
Identities = 81/392 (20%), Positives = 178/392 (45%), Gaps = 55/392 (14%)
Query: 32 LLALEEEYKRLNAELQAKT---ADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLR 88
++ L +E L ++QA+ AD ++ ++I+ + ++ ++ + + +DE++ +
Sbjct: 881 MVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAK-IKEVTERAEDEEEINAE 939
Query: 89 GLLPSEGIVHLHSETKPKTKNID-PVNKVQNKLHSANKGRK----------------TNS 131
+ SE K +++ + KV+ + H+ K T
Sbjct: 940 LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 999
Query: 132 SVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSND---- 187
L+ + QT DD+ + ED T++K + +LE++ +DD+ + +
Sbjct: 1000 KKALQEAHQQTLDDLQMEED-----KVNTLTKAKTKLEQQ-----VDDLEGSLEQEKKLC 1049
Query: 188 IGTEAQIRFLKAKLHVMQE---ELDNVVCECN----KKEDEIQNLKSQVKNFEEDFMRQQ 240
+ E R L+ L + QE + +N + N KKE E+ NL+ ++++ + ++ Q
Sbjct: 1050 MDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQ 1109
Query: 241 RTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELEN-KRRLQKQAASSQSATEV-- 297
+ I Q+++E+ + E ++Q S + RELE RL++ ++ + E+
Sbjct: 1110 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1169
Query: 298 -------RLNRALEEAE-KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELM 349
++ R LEE+ +++ + LR+ + D E ++I+ L+ +KLEK+K EL
Sbjct: 1170 KREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELK 1229
Query: 350 IGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEE 381
+ ++ + + K + E KM E++
Sbjct: 1230 MEINDLASNMETVSKAKANFE--KMCRTLEDQ 1259
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/184 (19%), Positives = 82/184 (44%), Gaps = 6/184 (3%)
Query: 116 VQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEE-EGLP 174
VQ ++ K +K + + +++ D + + ++ +T+ ++ +L+E E L
Sbjct: 1749 VQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLA 1808
Query: 175 EYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEE 234
+ G EA++R L++++ Q+ V K E ++ L Q + +
Sbjct: 1809 -----LKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRK 1863
Query: 235 DFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSA 294
+ +R Q ++ Q++V+ YK EEA ++ + + ++ ELE + A S +
Sbjct: 1864 NILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNK 1923
Query: 295 TEVR 298
V+
Sbjct: 1924 LRVK 1927
Score = 37.4 bits (85), Expect = 0.023
Identities = 47/202 (23%), Positives = 91/202 (45%), Gaps = 22/202 (10%)
Query: 193 QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEK 252
+I L + + + + N C ED++ S++K EE+ QQR IN +Q +
Sbjct: 1231 EINDLASNMETVSKAKANFEKMCRTLEDQL----SEIKTKEEE---QQRLINELSAQKAR 1283
Query: 253 YKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLE 312
T E +++ D +S + R KQA + Q L R LEE K K
Sbjct: 1284 LHTESGEFSRQLDEKDAMVSQLSR--------GKQAFTQQIE---ELKRQLEEETKAKST 1332
Query: 313 LSKLRQNNK---DIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHI 369
L+ Q+ + D+ E++++ + K+E ++ + + ++ + + D ++R +
Sbjct: 1333 LAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYE-TDAIQRTEELE 1391
Query: 370 EAAKMLSFTEEEFMKALEWGNS 391
EA K L+ ++ + +E NS
Sbjct: 1392 EAKKKLAQRLQDAEEHVEAVNS 1413
Score = 37.4 bits (85), Expect = 0.023
Identities = 64/330 (19%), Positives = 123/330 (37%), Gaps = 57/330 (17%)
Query: 36 EEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEG 95
EEE +RL EL A+ A + ++ E R DE D + L S G
Sbjct: 1267 EEEQQRLINELSAQKARLHTESGEFSRQL----------------DEKDAMVSQL--SRG 1308
Query: 96 IVHLHSETKPKTKNIDPVNKVQNKL-HSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSD 154
+ + + ++ K ++ L H+ R ++ +Y + Q A
Sbjct: 1309 KQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKA--------- 1359
Query: 155 FSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCE 214
L + +SK ++ + D + E + L +L +E ++ V +
Sbjct: 1360 -ELQRGMSKANSEVAQWRTKYETD----AIQRTEELEEAKKKLAQRLQDAEEHVEAVNSK 1414
Query: 215 CNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSV 274
C E Q L+++V++ D R + + + E +KY+ Q +L +
Sbjct: 1415 CASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEAS 1474
Query: 275 ERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIAN--------- 325
++E + S S ++ A EE+ + L L++ NK++
Sbjct: 1475 QKE-----------SRSLSTELFKVKNAYEESLDH---LETLKRENKNLQQEISDLTEQI 1520
Query: 326 -EEHKKIEVLKSENKKLEKQKGELMIGFKK 354
E K I L+ K+L+ +K EL ++
Sbjct: 1521 AEGGKHIHELEKVKKQLDHEKSELQTSLEE 1550
Score = 34.3 bits (77), Expect = 0.20
Identities = 70/401 (17%), Positives = 152/401 (37%), Gaps = 78/401 (19%)
Query: 36 EEEYKRLNAELQAKTADV---------VQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYS 86
+++Y+ AEL+A + V+ A E D E R + D +
Sbjct: 1461 KQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQI 1520
Query: 87 LRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSS----VKLKYSDVQT 142
+EG H+H K K + +++Q L A + ++L+ + V++
Sbjct: 1521 ------AEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKS 1574
Query: 143 ADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLH 202
D I E + QL+ L ++ + S + +I + +K K+
Sbjct: 1575 EIDRKIAEKDEELD----------QLKRNHL-RVVESMQSTLDAEIRSRNDALRIKKKME 1623
Query: 203 VMQEELDNVVCECNKKEDE----IQNLKSQVKNFE---------EDFMRQQ-----RTIN 244
E++ + N++ E ++N + +K+ + +D +++Q R N
Sbjct: 1624 GDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRAN 1683
Query: 245 MQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELE-----------NKRRLQKQAASSQS 293
+ Q++VE+ + E + +Q+L ++ K++L+ + Q
Sbjct: 1684 LMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQG 1743
Query: 294 A----------TEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEK 343
E + +A+ +A EL K + + + + + +K +L++
Sbjct: 1744 EMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDE 1803
Query: 344 QKGELMIGFKKQLKLI---------DVLKRQKMHIEAAKML 375
+ + G KKQ++ + +V QK ++EA K L
Sbjct: 1804 AEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGL 1844
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 65.9 bits (159), Expect = 6e-11
Identities = 86/366 (23%), Positives = 168/366 (45%), Gaps = 37/366 (10%)
Query: 37 EEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCD-------DEDDYSLRG 89
E+ + +L+AK +V ++A+E +E+ + + + K D D DD L
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEE----EEEINAELTAKKRKLEDECSELKKDIDDLELT- 963
Query: 90 LLPSEGIVHLHSETKPKTKNI-DPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAI 148
L E H T+ K KN+ + + + + +K +K L+ + QT DD+
Sbjct: 964 LAKVEKEKHA---TENKVKNLTEEMAGLDETIAKLSKEKKA-----LQETHQQTLDDLQA 1015
Query: 149 PEDFSDFSLAKTISKIEGQLEE-EGLPEYIDDIFSGVSN-DIGTEAQIRFLKAKLHVMQE 206
ED + L K +K+E Q+++ EG E + + E ++ + M+
Sbjct: 1016 EEDKVNI-LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMEN 1074
Query: 207 ELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDG 266
+ + + KKE EI NL S++++ + ++ Q+ I Q+++E+ E
Sbjct: 1075 DKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAK 1134
Query: 267 LQQQLSSVERELEN-KRRLQKQAASSQSATEV---------RLNRALEEAE-KYKLELSK 315
++Q S + RELE RL++ ++ + E+ +L R LEEA +++ ++
Sbjct: 1135 AEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAA 1194
Query: 316 LRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKML 375
LR+ + D E ++I+ L+ +KLEK+K EL + + + + K ++E KM
Sbjct: 1195 LRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLE--KMC 1252
Query: 376 SFTEEE 381
E++
Sbjct: 1253 RSLEDQ 1258
Score = 42.4 bits (98), Expect = 7e-04
Identities = 36/184 (19%), Positives = 80/184 (43%), Gaps = 6/184 (3%)
Query: 116 VQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEE-EGLP 174
+Q ++ K +K + + +++ D + + +L +T+ ++ +L+E E L
Sbjct: 1748 IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLA 1807
Query: 175 EYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEE 234
+ G EA++R L+ ++ Q+ V K E ++ L Q + +
Sbjct: 1808 -----LKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRK 1862
Query: 235 DFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSA 294
+ +R Q ++ Q++V+ YK EEA ++ + + ++ ELE A S +
Sbjct: 1863 NVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNK 1922
Query: 295 TEVR 298
V+
Sbjct: 1923 LRVK 1926
Score = 39.7 bits (91), Expect = 0.005
Identities = 67/356 (18%), Positives = 151/356 (42%), Gaps = 50/356 (14%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVS-----TQMKSCDDEDDY 85
+L ++++ ++ +EL+ +T D+ A+ I + + + S +++K+ ++E
Sbjct: 1212 NLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQR 1271
Query: 86 SLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYS-DVQTAD 144
+ L L +E ++ +D + + ++L S +K T +LK+ + +T
Sbjct: 1272 LINDLTAQRA--RLQTEAGEYSRQLDEKDALVSQL-SRSKQASTQQIEELKHQLEEETKA 1328
Query: 145 DVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIG-------TEA----- 192
A+ + + + + E+EG E + S ++++ T+A
Sbjct: 1329 KNALAHALQSSRHDCDLLREQYEEEQEGKAE-LQRALSKANSEVAQWRTKYETDAIQRTE 1387
Query: 193 QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEK 252
++ K KL +E + V N K ++ K +++N ED M N + ++K
Sbjct: 1388 ELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDK 1447
Query: 253 YKTLFE----EANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEK 308
+ F+ E +KY+ Q +L + ++E R L + ++ E L+
Sbjct: 1448 KQRNFDKVLSEWKQKYEETQAELEASQKE---SRSLSTELFKVKNVYEESLD-------- 1496
Query: 309 YKLELSKLRQNNKDIAN----------EEHKKIEVLKSENKKLEKQKGELMIGFKK 354
+L LR+ NK++ E K+I L+ K++E++K E+ ++
Sbjct: 1497 ---QLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEE 1549
Score = 38.5 bits (88), Expect = 0.011
Identities = 74/389 (19%), Positives = 153/389 (39%), Gaps = 59/389 (15%)
Query: 35 LEEEYKRLNAEL---QAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLL 91
LE ++L +L Q T D+ + K+ + ++ E + +S + +DE ++
Sbjct: 1051 LERAKRKLEGDLKLAQESTMDM-ENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQ--- 1106
Query: 92 PSEGIVHLHSETKPKTKNIDPVNK-VQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPE 150
L + K I+ + + ++ + S K K S + + ++ + A
Sbjct: 1107 -------LQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1159
Query: 151 DFSDFSLAKT----ISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQE 206
+ L K K+ LEE L EA + L+ K
Sbjct: 1160 TSAQVELNKKREAEFQKLRRDLEEATLQH---------------EAMVAALRKKHADSMA 1204
Query: 207 ELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQ-----------QSQVEKYKT 255
EL + + + +++ KS++K +D I+ + QV + KT
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKT 1264
Query: 256 LFEEANKKYDG-------LQQQLSSVERELENKRRLQKQAASSQSATEVR---LNRALEE 305
EE + + LQ + R+L+ K L Q + S+ A+ + L LEE
Sbjct: 1265 KEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEE 1324
Query: 306 AEKYKLELSKLRQNNK---DIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVL 362
K K L+ Q+++ D+ E++++ + K+E ++ + + ++ + + D +
Sbjct: 1325 ETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYE-TDAI 1383
Query: 363 KRQKMHIEAAKMLSFTEEEFMKALEWGNS 391
+R + EA K L+ +E + +E N+
Sbjct: 1384 QRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
Score = 37.0 bits (84), Expect = 0.031
Identities = 43/211 (20%), Positives = 80/211 (37%), Gaps = 45/211 (21%)
Query: 205 QEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVE------------- 251
++E+ + E K +DE+ +++ K EE + + N Q QV+
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 908
Query: 252 ------------KYKTLFEEANK----------KYDGLQQQLSSVERELENKRRLQKQAA 289
K K + E A + K L+ + S +++++++ +
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 290 SSQSATEVRLNRALEE----------AEKYKLELSKLRQNNKDIANEEHKKIEVLKSENK 339
+ ATE ++ EE K K L + Q D E K+ +L
Sbjct: 969 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 1028
Query: 340 KLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
KLE+Q +L +++ KL L+R K +E
Sbjct: 1029 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLE 1059
Score = 35.4 bits (80), Expect = 0.089
Identities = 34/154 (22%), Positives = 71/154 (46%), Gaps = 7/154 (4%)
Query: 199 AKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFE 258
A L M++ L+ V + + DE + L +K ++ + + + + +VE +
Sbjct: 1780 AHLERMKKNLEQTVKDLQHRLDEAEQLA--LKGGKKQIQKLEARVRELEGEVENEQKRNA 1837
Query: 259 EANK---KYDGLQQQLS-SVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELS 314
EA K K++ ++L+ E + +N RLQ Q+ + +A E E+ LS
Sbjct: 1838 EAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLS 1897
Query: 315 KLRQNNKDIANEEHKKIEVLKSENKKLEKQKGEL 348
K R+ ++ E ++ ++ +S+ KL + E+
Sbjct: 1898 KFRKLQHEL-EEAEERADIAESQVNKLRVKSREV 1930
Score = 33.1 bits (74), Expect = 0.44
Identities = 34/184 (18%), Positives = 82/184 (44%), Gaps = 20/184 (10%)
Query: 199 AKLHVMQEELDNVVCECNKKEDEIQ-NLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLF 257
A L Q D V+ E +K +E Q L++ K + N+ + +++ +TL
Sbjct: 1443 AALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLR 1502
Query: 258 EE---ANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAE------- 307
E ++ L +Q++ +++ +++KQ + + ALEEAE
Sbjct: 1503 RENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQE----KCEIQAALEEAEASLEHEE 1558
Query: 308 ----KYKLELSKLRQN-NKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVL 362
+ +LEL++++ ++ IA ++ + ++ ++ + +E + L + + + V
Sbjct: 1559 GKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVK 1618
Query: 363 KRQK 366
K+ +
Sbjct: 1619 KKME 1622
Score = 28.9 bits (63), Expect = 8.3
Identities = 39/194 (20%), Positives = 75/194 (38%), Gaps = 24/194 (12%)
Query: 201 LHVMQEELDNVVCECN-------KKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKY 253
+ MQ LD + N K E ++ ++ Q+ + R Q +++
Sbjct: 1597 VETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKET 1656
Query: 254 KTLFEEANKKYDGLQQQLSSVER-------ELENKRRLQKQAASSQSATEVRLNRALEEA 306
+ ++A + + L++QL+ VER E+E +Q S+ E L A E
Sbjct: 1657 QLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERV 1716
Query: 307 EKYKLELSKLRQNNKDIANE----EHKKIEVLKSENKKLEKQKGELMIG------FKKQL 356
+ + + L K + N+ + + EV++ EK K + KK+
Sbjct: 1717 QLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQ 1776
Query: 357 KLIDVLKRQKMHIE 370
L+R K ++E
Sbjct: 1777 DTSAHLERMKKNLE 1790
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 64.7 bits (156), Expect = 1e-10
Identities = 90/389 (23%), Positives = 178/389 (45%), Gaps = 46/389 (11%)
Query: 24 QPSTPGPDLLALEEEYKRL---NAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCD 80
Q +LL EE +L +L+AK +V ++A+ D +E+ + ++ + + +
Sbjct: 891 QVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAE----DEEEINAE-LTAKKRKLE 945
Query: 81 DEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANK--GRKTNSSVKLKYS 138
DE + + E + + K T+N V + +L ++ + T L+ +
Sbjct: 946 DECSELKKDIDDLELTLAKVEKEKHATEN--KVKNLTEELSGLDETIAKLTREKKALQEA 1003
Query: 139 DVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSND----IGTEAQI 194
Q DD+ ED + SL KT SK+E Q+E D+ S + + + E
Sbjct: 1004 HQQALDDLQAEEDKVN-SLNKTKSKLEQQVE---------DLESSLEQEKKLRVDLERNK 1053
Query: 195 RFLKAKLHVMQE---ELDNVVCECN----KKEDEIQNLKSQVKNFEEDFMRQQRTINMQQ 247
R L+ L + QE +L+N + + KK+ E L+S+V++ + ++ Q+ I Q
Sbjct: 1054 RKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQ 1113
Query: 248 SQVEKYKTLFEEANKKYDGLQQQLSSVERELEN-KRRLQKQAASSQSATEV--------- 297
+++E+ + E ++Q S RELE RL++ + + E+
Sbjct: 1114 ARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFL 1173
Query: 298 RLNRALEEAE-KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQL 356
+L R LEEA +++ ++ LR+ + D E ++I+ L+ +KLEK+K E +
Sbjct: 1174 KLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLS 1233
Query: 357 KLIDVLKRQKMHIEAAKMLSFTEEEFMKA 385
++ + + K ++E K+ E++ +A
Sbjct: 1234 SSMESVSKSKANLE--KICRTLEDQLSEA 1260
Score = 40.4 bits (93), Expect = 0.003
Identities = 48/211 (22%), Positives = 96/211 (45%), Gaps = 27/211 (12%)
Query: 191 EAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQV 250
EA + L+ K EL + + + +++ KS+ K +D +++ ++ +
Sbjct: 1187 EAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 1246
Query: 251 EKY-KTL---FEEANKKYDGLQQQLS--------------SVERELENKRRLQKQAASSQ 292
EK +TL EA K + +Q+ LS + R+LE K + Q + S+
Sbjct: 1247 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 1306
Query: 293 SA----TEVRLNRALEEAEKYKLELSKLRQNNK---DIANEEHKKIEVLKSENKKLEKQK 345
A TE L R LEE K K L+ Q+++ D+ E++++ + K+E ++ +
Sbjct: 1307 QAFTQQTE-ELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA 1365
Query: 346 GELMIGFKKQLKLIDVLKRQKMHIEAAKMLS 376
+ ++ + + D ++R + EA K L+
Sbjct: 1366 NSEVAQWRTKYE-TDAIQRTEELEEAKKKLA 1395
Score = 40.4 bits (93), Expect = 0.003
Identities = 50/244 (20%), Positives = 110/244 (45%), Gaps = 14/244 (5%)
Query: 45 ELQAKTADVVQQAKEIIRDRQEVRSRPVSTQM--KSCDDE--DDYSLRGLLPSEGIVHLH 100
+L+ + A V ++A + + +E+R+ T+ K + E D LL ++ +H
Sbjct: 1667 DLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH 1726
Query: 101 SETKPKTKNIDPVNKVQNKLHSAN----KGRKTNSSVKLKYSDVQTADDVAIPEDFSDFS 156
++ K +T + ++V++ A K +K + + +++ D + + +
Sbjct: 1727 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1786
Query: 157 LAKTISKIEGQLEE-EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCEC 215
L +T+ ++ +L+E E L + G E +IR L+ +L Q++ V
Sbjct: 1787 LEQTVKDLQHRLDEAEQLA-----LKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGL 1841
Query: 216 NKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVE 275
K E ++ L Q + ++ +R Q ++ Q +V+ YK EEA+++ + + +
Sbjct: 1842 RKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQ 1901
Query: 276 RELE 279
ELE
Sbjct: 1902 HELE 1905
Score = 37.4 bits (85), Expect = 0.023
Identities = 63/345 (18%), Positives = 125/345 (36%), Gaps = 49/345 (14%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSR--PVSTQMKSCDDEDDYSLR 88
DL + E + A L+ + Q E +E++ ++TQ E R
Sbjct: 1231 DLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSR 1290
Query: 89 GLLPSEGIVHLHS--------ETKPKTKNIDPVNKVQNKL-HSANKGRKTNSSVKLKYSD 139
L E IV S +T+ + ++ NK +N L H+ R ++ +Y +
Sbjct: 1291 QLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEE 1350
Query: 140 VQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKA 199
Q L + +SK ++ + D + E + L
Sbjct: 1351 EQEGKA----------ELQRALSKANSEVAQWRTKYETD----AIQRTEELEEAKKKLAQ 1396
Query: 200 KLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEE 259
+L +E+++ V +C E Q L+ +V++ D R + + + E
Sbjct: 1397 RLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAE 1456
Query: 260 ANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQN 319
K + Q +L E L+ R L + ++A E L+ +L +++
Sbjct: 1457 WKTKCEESQAEL---EASLKESRSLSTELFKLKNAYEEALD-----------QLETVKRE 1502
Query: 320 NKDIAN----------EEHKKIEVLKSENKKLEKQKGELMIGFKK 354
NK++ E K I L+ K++E +K ++ + ++
Sbjct: 1503 NKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEE 1547
Score = 35.0 bits (79), Expect = 0.12
Identities = 62/275 (22%), Positives = 117/275 (42%), Gaps = 46/275 (16%)
Query: 120 LHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKI-EGQLEEEGLPEYID 178
+H K RK ++L+ +D+Q A + A + +L +KI QLE + ID
Sbjct: 1524 IHELEKSRK---QIELEKADIQLALEEA------EAALEHEEAKILRIQLELTQVKSEID 1574
Query: 179 DIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECN-------KKEDEIQNLKSQVKN 231
+ +I E R + + MQ LD V N K E ++ ++ Q+ +
Sbjct: 1575 RKIAEKDEEI--EQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSH 1632
Query: 232 FEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASS 291
+ + Q Q++ + ++A + + L++QL+ VER A+
Sbjct: 1633 ANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERR-----------ANL 1681
Query: 292 QSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIG 351
A L LE+ E+ + KL + +NE ++++L ++N L I
Sbjct: 1682 LQAEVEELRATLEQTERAR----KLAEQELLDSNE---RVQLLHTQNTSL--------IH 1726
Query: 352 FKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFMKAL 386
KK+L+ D+++ Q +A++ EE+ KA+
Sbjct: 1727 TKKKLE-TDLMQLQSEVEDASRDARNAEEKAKKAI 1760
Score = 34.3 bits (77), Expect = 0.20
Identities = 42/211 (19%), Positives = 79/211 (37%), Gaps = 45/211 (21%)
Query: 205 QEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVE------------- 251
++E+ + E K +DE+ +++ K EE + + N Q QV+
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906
Query: 252 ------------KYKTLFE----------EANKKYDGLQQQLSSVERELENKRRLQKQAA 289
K K + E E K L+ + S +++++++ +
Sbjct: 907 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966
Query: 290 SSQSATEVRLNRALEEAEKYKLELSKLRQNNK----------DIANEEHKKIEVLKSENK 339
+ ATE ++ EE ++KL + K D E K+ L
Sbjct: 967 KEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKS 1026
Query: 340 KLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
KLE+Q +L +++ KL L+R K +E
Sbjct: 1027 KLEQQVEDLESSLEQEKKLRVDLERNKRKLE 1057
Score = 32.7 bits (73), Expect = 0.58
Identities = 32/192 (16%), Positives = 78/192 (40%), Gaps = 20/192 (10%)
Query: 156 SLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCE- 214
SL KT +++G++E D+ V + L A L Q D V+ E
Sbjct: 1414 SLEKTKQRLQGEVE---------DLMVDVE-------RANSLAAALDKKQRNFDKVLAEW 1457
Query: 215 ---CNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQL 271
C + + E++ + ++ + + + Q+E K + ++ L +Q+
Sbjct: 1458 KTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQI 1517
Query: 272 SSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKI 331
+ + + + +KQ ++ ++ L A E + ++ +++ + +E +KI
Sbjct: 1518 AENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKI 1577
Query: 332 EVLKSENKKLEK 343
E ++L++
Sbjct: 1578 AEKDEEIEQLKR 1589
>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
[Homo sapiens]
Length = 1235
Score = 64.7 bits (156), Expect = 1e-10
Identities = 44/174 (25%), Positives = 85/174 (48%), Gaps = 18/174 (10%)
Query: 200 KLHVMQEELDNVVCECNKKEDEIQNLKSQV-----------KNFEEDFMRQQRTINMQQS 248
KL V ++ + + +C+K+ED+I+ L++++ K EE+ + ++R I ++ S
Sbjct: 311 KLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHKKRDIELEAS 370
Query: 249 QVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEK 308
Q+++YK L E+ KK + QQL ++ E + + L + E+ E
Sbjct: 371 QLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGEVQGNLKQIKEQIED 430
Query: 309 YKLELSKLRQNNK---DIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLI 359
+K + KL + K D E+ ++ E L E +K + + E F ++L LI
Sbjct: 431 HKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSE----FNEELNLI 480
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 59.3 bits (142), Expect = 6e-09
Identities = 37/175 (21%), Positives = 88/175 (50%), Gaps = 3/175 (1%)
Query: 187 DIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQ 246
D ++ L ++ +Q E +NV + +KED I+ S+V++ +++ R+ +
Sbjct: 328 DFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKL 387
Query: 247 QSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEA 306
Q+Q ++ + L +E +++ L++QL V ++ + +L + ++ E +++ EE
Sbjct: 388 QAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEEL 447
Query: 307 EKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDV 361
K + ELS+L+Q ++ L+ + L+ + E+ Q+KL+++
Sbjct: 448 AKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEIS---SMQMKLMEM 499
Score = 33.5 bits (75), Expect = 0.34
Identities = 32/195 (16%), Positives = 87/195 (44%), Gaps = 10/195 (5%)
Query: 88 RGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVA 147
+ ++ S + + + T N + V+ + K + ++ ++K + S+VQ D
Sbjct: 318 KNIIGSSPVADFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEV 377
Query: 148 IPEDFSDFSLAKTISKIEGQLEE-EGLPEYIDDIFSGVSNDIGTEAQ-IRFLKAKLHVMQ 205
E+ + L +++ L+E + +++ V EAQ I LKA+L +
Sbjct: 378 QRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQE 437
Query: 206 EELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYD 265
++ E+E+ + ++ +++ + ++ ++Q+E + +++ ++
Sbjct: 438 SQISTY-------EEELAKAREELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEIS 490
Query: 266 GLQQQLSSVERELEN 280
+Q +L + ++LEN
Sbjct: 491 SMQMKLMEM-KDLEN 504
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 59.3 bits (142), Expect = 6e-09
Identities = 57/200 (28%), Positives = 101/200 (50%), Gaps = 11/200 (5%)
Query: 170 EEGLPEYIDDIFSGVSNDIGTE-AQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQ 228
EE + E + + G S I T+ ++I ++ + V+Q E + + ED+I+++ +
Sbjct: 262 EERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKK 321
Query: 229 VKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERE--LENKRRLQK 286
+ + E D R +Q VEK + + E N K + + Q S+V++ + K R+
Sbjct: 322 LSSAEND--RDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILA 379
Query: 287 QAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHK---KIEVLKSENKKLEK 343
Q+AS + RL +AL +AE + LS L Q+N +A + K +IEVL+ E L +
Sbjct: 380 QSASVEEV--FRLQQALSDAENEIMRLSSLNQDN-SLAEDNLKLKMRIEVLEKEKSLLSQ 436
Query: 344 QKGELMIGFKKQLKLIDVLK 363
+K EL + K +V+K
Sbjct: 437 EKEELQMSLLKLNNEYEVIK 456
Score = 47.8 bits (112), Expect = 2e-05
Identities = 59/325 (18%), Positives = 135/325 (41%), Gaps = 17/325 (5%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQE---VRSRPVSTQMKSCDDEDDYSLRGLL 91
LE++ K +N +L + D ++I+R QE V R + + ++ E +
Sbjct: 311 LEDKIKDINKKLSSAEND-----RDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAV 365
Query: 92 PSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPED 151
+ ++ +++ V ++Q L A SS L + D++ +
Sbjct: 366 KQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSS--LNQDNSLAEDNLKLKMR 423
Query: 152 FSDFSLAKTI---SKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEEL 208
K++ K E Q+ L + I S + DI ++++ L+ L ++EL
Sbjct: 424 IEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQEL 483
Query: 209 DNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQ----VEKYKTLFEEANKKY 264
+ + E EI+ L Q + + + + ++ QQ++ + K K + K+
Sbjct: 484 NQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRV 543
Query: 265 DGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIA 324
L+ + +EL+ ++ Q+ + + + + ++ E +L+K +++N I
Sbjct: 544 HQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQ 603
Query: 325 NEEHKKIEVLKSENKKLEKQKGELM 349
E + E ++ ++L + + ELM
Sbjct: 604 KENLELKEHIRQNEEELSRIRNELM 628
Score = 45.1 bits (105), Expect = 1e-04
Identities = 74/332 (22%), Positives = 140/332 (42%), Gaps = 28/332 (8%)
Query: 56 QAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNK 115
+ KE IR +E SR + M+S + + + + + L E +E + +N+ + +
Sbjct: 608 ELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKER----EAEVRNLKQNLSELEQ 663
Query: 116 VQNKLHS-ANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAK-----TISKIEGQLE 169
+ L A + N + L DV+ + + + + SL K T+ +G++E
Sbjct: 664 LNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGN-NQLSLEKNTIVETLKMEKGEIE 722
Query: 170 EE--GLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKS 227
E + + + + I + R L +Q E ++++ KK+ EI LK
Sbjct: 723 AELCWAKKRLLEEANKYEKTIEELSNARNLNTS--ALQLEHEHLIKLNQKKDMEIAELKK 780
Query: 228 QVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKK---YDGLQQQLSSVERELEN-KRR 283
++ + D + T ++ S +E+ K L + NKK + L+++ S ++ EL+ +
Sbjct: 781 NIEQMDTD---HKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQA 837
Query: 284 LQKQAASSQSATEV--RLNRALEEAEKYKLELSKLRQNNKDIANEEHKK----IEVLKSE 337
L+K Q+ E L EE + EL +LR+ A K + L SE
Sbjct: 838 LRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASE 897
Query: 338 NKKLEKQKGELMIGFKKQLKLIDVLKRQKMHI 369
+L K L K K+I+ + KM +
Sbjct: 898 VSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQL 929
Score = 43.1 bits (100), Expect = 4e-04
Identities = 47/220 (21%), Positives = 98/220 (44%), Gaps = 27/220 (12%)
Query: 188 IGTEAQIRFLKAKLHVMQEELDNVVCECNKKED-------EIQNLKSQVKNFEEDFMRQQ 240
I +E + L ++++++N+V + NK ++ E LK ++ EE+ R +
Sbjct: 565 IQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIR 624
Query: 241 RTI--NMQQSQVEKYK-TLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEV 297
+ ++ Q +K TL +E + L+Q LS +E+ EN L+K A + E
Sbjct: 625 NELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNEN---LKKVAFDVKMENE- 680
Query: 298 RLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQ----KGELMIGFK 353
+ + E + +L + N ++ E++ +E LK E ++E + K L+
Sbjct: 681 ---KLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEAN 737
Query: 354 KQLKLIDVLKRQK------MHIEAAKMLSFTEEEFMKALE 387
K K I+ L + + +E ++ +++ M+ E
Sbjct: 738 KYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAE 777
Score = 31.2 bits (69), Expect = 1.7
Identities = 21/102 (20%), Positives = 45/102 (44%)
Query: 202 HVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEAN 261
H QEE E K++ I K +N E + Q ++ + ++ L E+ +
Sbjct: 1682 HFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLD 1741
Query: 262 KKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRAL 303
K + +++ E E +QK+ S +++E ++++ L
Sbjct: 1742 VKEEQIEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKVL 1783
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 59.3 bits (142), Expect = 6e-09
Identities = 79/382 (20%), Positives = 167/382 (43%), Gaps = 59/382 (15%)
Query: 32 LLALEEEYKRLNAELQAKTA---DVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLR 88
+++L +E L ++QA+ D ++ ++I+++ ++ ++ V + +DE++ +
Sbjct: 879 MVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAK-VKEMNERLEDEEEMNAE 937
Query: 89 GLLPSEGIVHLHSETKPKTKNID-PVNKVQNKLHSANKGRK----------------TNS 131
+ SE K +++ + KV+ + H+ K T
Sbjct: 938 LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE 997
Query: 132 SVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTE 191
L+ + Q DD+ + ED + SL+K+ K+E Q +DD+ + +
Sbjct: 998 KKALQEAHQQALDDLQVEEDKVN-SLSKSKVKLEQQ---------VDDLEGSLEQEKKVR 1047
Query: 192 AQIRFLKAKLH---------VMQEELDNVVCE--CNKKEDEIQNLKSQVKNFEEDFMRQQ 240
+ K KL +M E D + E KKE +I S++++ + ++ Q
Sbjct: 1048 MDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQ 1107
Query: 241 RTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELEN-KRRLQKQAASSQSATEV-- 297
+ + Q+++E+ + E +++ S + RELE RL++ ++ E+
Sbjct: 1108 KKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNK 1167
Query: 298 -------RLNRALEEAE-KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELM 349
++ R LEEA +++ + LR+ + D E ++I+ L+ +KLEK+K E
Sbjct: 1168 KREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEF- 1226
Query: 350 IGFKKQLKLIDVLKRQKMHIEA 371
+L+L DV + I+A
Sbjct: 1227 -----KLELDDVTSNMEQIIKA 1243
Score = 45.8 bits (107), Expect = 7e-05
Identities = 67/351 (19%), Positives = 149/351 (42%), Gaps = 39/351 (11%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGL 90
++ L+E +L E +A + QQA + ++ ++ + +++K DD L G
Sbjct: 983 EMAGLDEIIAKLTKEKKA-LQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDD--LEGS 1039
Query: 91 LPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPE 150
L E V + E + D ++ + N + +K K D+ + E
Sbjct: 1040 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDE 1099
Query: 151 DFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDN 210
L K + + + ++EE + ++ E R +AK+ ++ +L
Sbjct: 1100 QVLALQLQKKLKENQARIEE-------------LEEELEAE---RTARAKVEKLRSDLSR 1143
Query: 211 VVCECNKKEDEIQNLKS----QVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDG 266
+ E +++ +E S K E +F + +R +++++ ++ T K D
Sbjct: 1144 ELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR--DLEEATLQHEATAAALRKKHADS 1201
Query: 267 LQQQLSSVERELENKRRLQKQAASSQSATEVRLNRA---LEEAEKYKLELSKLRQNNKDI 323
+ + + +++N +R++++ +S ++ L+ +E+ K K L K+ + +D
Sbjct: 1202 VAE----LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQ 1257
Query: 324 ANEEHKKIEVLK-------SENKKLEKQKGELMIGFKKQLKLIDVLKRQKM 367
ANE K+E + ++ KL+ + GEL +++ LI L R K+
Sbjct: 1258 ANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKL 1308
Score = 44.7 bits (104), Expect = 1e-04
Identities = 60/299 (20%), Positives = 126/299 (42%), Gaps = 41/299 (13%)
Query: 41 RLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLH 100
R N +L+ A V ++ + + +E+R+ T+ E + + SE + LH
Sbjct: 1664 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQEL----IETSERVQLLH 1719
Query: 101 SET----KPKTKNIDPVNKVQNKLHSA--------NKGRKTNSSVKLKYSDVQTADDVAI 148
S+ K K + ++Q+++ A K +K + + +++ D +
Sbjct: 1720 SQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSA 1779
Query: 149 PEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEEL 208
+ ++ +TI ++ +L+E E I + G EA++R L+ +L Q+
Sbjct: 1780 HLERMKKNMEQTIKDLQHRLDEA---EQIA-LKGGKKQLQKLEARVRELEGELEAEQKRN 1835
Query: 209 DNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQ 268
V K E I+ L Q + +++ +R Q ++ Q +V+ YK EEA ++ +
Sbjct: 1836 AESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNL 1895
Query: 269 QQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEE 327
+ V+ EL+ A E A+ + +++KLR ++DI ++
Sbjct: 1896 SKFRKVQHELD---------------------EAEERADIAESQVNKLRAKSRDIGAKQ 1933
Score = 42.7 bits (99), Expect = 6e-04
Identities = 71/362 (19%), Positives = 146/362 (40%), Gaps = 60/362 (16%)
Query: 32 LLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLL 91
+L + E+ ++ AE++ K A+ ++ ++ R+ Q V V + S D E L
Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRV----VDSLQTSLDAETRSRNEVL- 1614
Query: 92 PSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANK-GRKTNSSVK-----LKYSDVQTADD 145
+ K K +N+++ +L AN+ + VK LK + +Q D
Sbjct: 1615 ------------RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1662
Query: 146 VAIPEDFSDF----------------SLAKTISKIEG--QLEEEGLPEYIDDIFSGVSND 187
V +D + L + + E +L E+ L E + + S +
Sbjct: 1663 VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQN 1722
Query: 188 IGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTI---- 243
Q + +++ L +Q E++ V EC E++ + + E+ ++Q T
Sbjct: 1723 TSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1782
Query: 244 ----NMQQSQVEKYKTLFEEANKKYDGLQQQLSSV---ERELEN----KRRLQKQAASSQ 292
NM+Q+ + L E G ++QL + RELE +++ ++
Sbjct: 1783 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842
Query: 293 SATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGF 352
+E R+ + E+ K L +L +D+ ++ K++ K + ++ E+Q + F
Sbjct: 1843 RKSERRIKELTYQTEEDKKNLLRL----QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKF 1898
Query: 353 KK 354
+K
Sbjct: 1899 RK 1900
Score = 39.3 bits (90), Expect = 0.006
Identities = 45/192 (23%), Positives = 82/192 (42%), Gaps = 24/192 (12%)
Query: 198 KAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLF 257
K KL ++ + V N K ++ K +++N ED M N + ++K + F
Sbjct: 1392 KKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF 1451
Query: 258 E----EANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLEL 313
+ E +KY+ Q +L S ++E A S S +L A EE+ ++ L
Sbjct: 1452 DKILAEWKQKYEESQSELESSQKE-----------ARSLSTELFKLKNAYEESLEH---L 1497
Query: 314 SKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAK 373
++ NK++ E E L K + + + +KQL+ ++ L+ Q EA
Sbjct: 1498 ETFKRENKNLQEEISDLTEQLGEGGKNVHE-----LEKVRKQLE-VEKLELQSALEEAEA 1551
Query: 374 MLSFTEEEFMKA 385
L E + ++A
Sbjct: 1552 SLEHEEGKILRA 1563
Score = 35.8 bits (81), Expect = 0.068
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 31/160 (19%)
Query: 192 AQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVE 251
A+ L+ H +Q E+++++ + + L + +NF++
Sbjct: 1411 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK----------------- 1453
Query: 252 KYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKL 311
+ E +KY+ Q +L S ++E R L + ++A E +LE E +K
Sbjct: 1454 ----ILAEWKQKYEESQSELESSQKE---ARSLSTELFKLKNAYE----ESLEHLETFKR 1502
Query: 312 ELSKLRQNNKDIA---NEEHKKIEVLKSENKKLEKQKGEL 348
E L++ D+ E K + L+ K+LE +K EL
Sbjct: 1503 ENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLEL 1542
Score = 35.0 bits (79), Expect = 0.12
Identities = 58/254 (22%), Positives = 105/254 (41%), Gaps = 18/254 (7%)
Query: 143 ADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLH 202
AD VA + D +L + K+E + E L +DD+ S + QI KA L
Sbjct: 1199 ADSVAELGEQID-NLQRVKQKLEKEKSEFKLE--LDDVTSNME-------QIIKAKANLE 1248
Query: 203 VMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANK 262
+ L++ E K +E Q + +F + Q Q+E+ + L + +
Sbjct: 1249 KVSRTLEDQANEYRVKLEEAQR---SLNDFTTQRAKLQTENGELARQLEEKEALISQLTR 1305
Query: 263 KYDGLQQQLSSVERELENKRRLQKQAASS-QSATE--VRLNRALEEAEKYKLELSK-LRQ 318
QQ+ ++R+LE + + + A + QSA L EE + K EL + L +
Sbjct: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1365
Query: 319 NNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAK-MLSF 377
N ++A K ++LE+ K +L + + ++ + + +E K L
Sbjct: 1366 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
Query: 378 TEEEFMKALEWGNS 391
E+ M +E N+
Sbjct: 1426 EIEDLMVDVERSNA 1439
Score = 32.7 bits (73), Expect = 0.58
Identities = 28/169 (16%), Positives = 69/169 (40%), Gaps = 14/169 (8%)
Query: 199 AKLHVMQEELDNVVCECNKK----EDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYK 254
A L Q D ++ E +K + E+++ + + ++ + + + +E +K
Sbjct: 1442 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1501
Query: 255 TLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELS 314
+ ++ L +QL + + +++KQ ++ L ALEEAE +
Sbjct: 1502 RENKNLQEEISDLTEQLGEGGKNVHELEKVRKQL----EVEKLELQSALEEAE------A 1551
Query: 315 KLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLK 363
L I + + ++ +KL ++ E+ + +++D L+
Sbjct: 1552 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 58.9 bits (141), Expect = 8e-09
Identities = 78/392 (19%), Positives = 165/392 (42%), Gaps = 62/392 (15%)
Query: 34 ALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEV-RSRPVSTQMKSCDDEDDYSLRGLLP 92
AL+EE + A++Q Q +E+ ++ R++ + K ++++ L G L
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1241
Query: 93 SEGIVHLHSETKPKTKNIDP-VNKVQNKLHSANKGR-KTNSSVKLKYSDVQTADDVAIPE 150
G E + K K ++ V ++Q+K + R + N V ++V++ +
Sbjct: 1242 VLG--QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299
Query: 151 DFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDN 210
+ LAK ++ + QL++ E + + + ++R L+ + + +Q++LD
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDT--QELLQE---ETRQKLNVSTKLRQLEEERNSLQDQLDE 1354
Query: 211 VV--------------CECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTL 256
+ + + + ++Q+ S V+ EE R Q+ I Q E+
Sbjct: 1355 EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1414
Query: 257 FEEANKKYDGLQQQLSSVERELENKRRL----------------QKQAASSQSATE---- 296
+++ K + LQQ+L + +L+N+R+L +++ SS+ A E
Sbjct: 1415 YDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 297 -----------VRLNRALEEAEKYKLELSK----LRQNNKDIANEEH---KKIEVLKSEN 338
+ L RALEEA + K EL + L+ +D+ + + K + L+
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 339 KKLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
+ LE Q E+ ++ + + K+ +E
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLE 1566
Score = 50.8 bits (120), Expect = 2e-06
Identities = 80/352 (22%), Positives = 145/352 (41%), Gaps = 41/352 (11%)
Query: 35 LEEEYKR---LNAE---LQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLR 88
LEEE R L AE + + D+ +Q +E RQ+++ V+ + K ED+
Sbjct: 931 LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI--- 987
Query: 89 GLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAI 148
L+ + L E K + I + + A + K + KLK ++ +
Sbjct: 988 -LVMDDQNNKLSKERKLLEERISDLTT-----NLAEEEEKAKNLTKLKNKHESMISELEV 1041
Query: 149 ---PEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQ 205
E+ S L K K+EG + E I D+ +AQI LK +L +
Sbjct: 1042 RLKKEEKSRQELEKLKRKLEGDASD--FHEQIADL----------QAQIAELKMQLAKKE 1089
Query: 206 EELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYD 265
EEL + + +DEI + +K E + I+ Q ++ + +A K+
Sbjct: 1090 EELQAALA---RLDDEIAQKNNALKKIRE----LEGHISDLQEDLDSERAARNKAEKQKR 1142
Query: 266 GLQQQLSSVERELEN---KRRLQKQAASSQSATEVRLNRAL-EEAEKYKLELSKLRQNNK 321
L ++L +++ ELE+ Q++ + + L +AL EE ++ ++ ++RQ +
Sbjct: 1143 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1202
Query: 322 DIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAK 373
E +++E K L+K K L + VL + K +E K
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKK 1254
Score = 46.2 bits (108), Expect = 5e-05
Identities = 79/398 (19%), Positives = 163/398 (40%), Gaps = 83/398 (20%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRS---------RPVSTQMKSCDD 81
+ L +EE +R N L+A+ D+V ++ ++ E+ + TQ++ +D
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
Query: 82 E----DDYSLR---GLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHS-------ANKGR 127
E +D LR + +G + + + +N + ++Q +LH K R
Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDE-QNEEKRRQLQRQLHEYETELEDERKQR 1612
Query: 128 KTNSSVKLKYS----DVQTADDVAIPEDFSDFSLAKTISKIEGQLEE-----EGLPEYID 178
++ K K D++ D AI K + K++ Q+++ E D
Sbjct: 1613 ALAAAAKKKLEGDLKDLELQADSAIK---GREEAIKQLRKLQAQMKDFQRELEDARASRD 1669
Query: 179 DIFSGVSNDIGTEAQIRFLKAKLHVMQE---------------------ELDNVVCECNK 217
+IF+ + E + + L+A L +QE EL + + N
Sbjct: 1670 EIFATAKEN---EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1726
Query: 218 KEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEAN----------KKYDGL 267
+DE + L++++ EE+ +Q + +V K E+ + +K +
Sbjct: 1727 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1786
Query: 268 QQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEE 327
+QQL +EL +K + A S+ + + ALE ++++L + + A E+
Sbjct: 1787 RQQLERQNKELRSKLHEMEGAVKSKFKSTI---AALE------AKIAQLEEQVEQEAREK 1837
Query: 328 HKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQ 365
+ LK ++KKL+ E+++ + + K+ + K Q
Sbjct: 1838 QAATKSLKQKDKKLK----EILLQVEDERKMAEQYKEQ 1871
Score = 42.7 bits (99), Expect = 6e-04
Identities = 74/370 (20%), Positives = 154/370 (41%), Gaps = 55/370 (14%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSE 94
L EE L +LQA+T E+ + +E+R R + + + + + R +
Sbjct: 885 LTEEKNLLQEQLQAET--------ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED 936
Query: 95 GIVHLHSETKPKTKNIDPVNKVQNKLHSANKG---RKTNSSVKLKYSDVQTADDVAIPED 151
L +E K + + + + + +A + K + K+K + D++ + +D
Sbjct: 937 RGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK----KLEDEILVMDD 992
Query: 152 FSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNV 211
++ +SK E + L E I D+ + ++ + + LK K M EL+
Sbjct: 993 QNN-----KLSK-----ERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 212 VCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQL 271
+ + K E++ LK +++ DF Q I Q+Q+ + K + KK + LQ L
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQ---IADLQAQIAELKM---QLAKKEEELQAAL 1096
Query: 272 SSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKI 331
+ ++ E+ K K+ E ++ E+ + + +K + +D+ E +
Sbjct: 1097 ARLDDEIAQKNNALKKIRE----LEGHISDLQEDLDSERAARNKAEKQKRDLGEE----L 1148
Query: 332 EVLKSE----------NKKLEKQKGELMIGFKKQL------KLIDVLKRQKMHIEAAKML 375
E LK+E ++L ++ + + KK L V + ++ H +A + L
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1208
Query: 376 SFTEEEFMKA 385
+ E+F +A
Sbjct: 1209 TEQLEQFKRA 1218
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/295 (22%), Positives = 126/295 (42%), Gaps = 47/295 (15%)
Query: 106 KTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSD-VQTADDVAIPEDFSDFSLAKTISKI 164
+TK + ++ L + + +TN +K + D V + DDV + L K+ +
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK----NVHELEKSKRAL 1537
Query: 165 EGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEI 222
E Q+EE L E D++ + + E ++ LK + + D + E++
Sbjct: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE------QNEEKR 1591
Query: 223 QNLKSQVKNFEEDFM--RQQRTI----------NMQQSQVEKYKTLF--EEANKKYDGLQ 268
+ L+ Q+ +E + R+QR + +++ +++ + EEA K+ LQ
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 269 QQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEH 328
Q+ +RELE+ R + + ++ A E +K K + L Q +D+A E
Sbjct: 1652 AQMKDFQRELEDARASRDEIFAT----------AKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 329 KKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEA--AKMLSFTEEE 381
+ K+ + +K EL L + L+ +K +EA A++ EEE
Sbjct: 1702 AR--------KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1748
Score = 40.0 bits (92), Expect = 0.004
Identities = 73/339 (21%), Positives = 145/339 (42%), Gaps = 62/339 (18%)
Query: 35 LEEEYKR------LNAELQAKTADVVQQAKEIIRDRQEV--RSRPVSTQMKSCDDEDDYS 86
LE+E K+ +L+ D+ QA I+ R+E + R + QMK E + +
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Query: 87 LRGLLPSEGIVHLHSETKPKTKNIDP-VNKVQNKLHSANKGRKTNSSVKLKYSDVQTADD 145
+ I E + K K+++ + ++Q L +A + RK K + ++ + A
Sbjct: 1665 RAS---RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE-ELASS 1720
Query: 146 VAIPEDFSDFS--LAKTISKIEGQLEEE-GLPEYIDDIF-------SGVSNDIGTEA--- 192
++ D L I+++E +LEEE G E + D +SN++ TE
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1780
Query: 193 ------------QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQ 240
Q + L++KLH M+ + + K + I L++++ EE ++
Sbjct: 1781 QKNESARQQLERQNKELRSKLHEMEGAVKS------KFKSTIAALEAKIAQLEEQVEQEA 1834
Query: 241 R-----TINMQQS---------QVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQK 286
R T +++Q QVE + + E+ ++ + ++ ++R+LE +
Sbjct: 1835 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1894
Query: 287 QAASSQSATEVRLNRALEEAEKYKLEL----SKLRQNNK 321
+ +++ + L+ A E E E+ SKLR+ N+
Sbjct: 1895 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
Score = 38.5 bits (88), Expect = 0.011
Identities = 42/165 (25%), Positives = 75/165 (45%), Gaps = 21/165 (12%)
Query: 193 QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEK 252
Q+ + ++ ++EL K E+E++ L+ + E+ N+ Q Q++
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-------KNLLQEQLQA 898
Query: 253 YKTLFEEANK-------KYDGLQQQLSSVERELENK--RRLQKQAASSQSATE-VRLNRA 302
L+ EA + K L++ L +E LE + R Q QA + A + + L
Sbjct: 899 ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 958
Query: 303 LEEAE--KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQK 345
LEE E + KL+L K+ K E+ +I V+ +N KL K++
Sbjct: 959 LEEEEAARQKLQLEKVTAEAKIKKLED--EILVMDDQNNKLSKER 1001
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 58.9 bits (141), Expect = 8e-09
Identities = 78/392 (19%), Positives = 165/392 (42%), Gaps = 62/392 (15%)
Query: 34 ALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEV-RSRPVSTQMKSCDDEDDYSLRGLLP 92
AL+EE + A++Q Q +E+ ++ R++ + K ++++ L G L
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1248
Query: 93 SEGIVHLHSETKPKTKNIDP-VNKVQNKLHSANKGR-KTNSSVKLKYSDVQTADDVAIPE 150
G E + K K ++ V ++Q+K + R + N V ++V++ +
Sbjct: 1249 VLG--QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306
Query: 151 DFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDN 210
+ LAK ++ + QL++ E + + + ++R L+ + + +Q++LD
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDT--QELLQE---ETRQKLNVSTKLRQLEEERNSLQDQLDE 1361
Query: 211 VV--------------CECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTL 256
+ + + + ++Q+ S V+ EE R Q+ I Q E+
Sbjct: 1362 EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1421
Query: 257 FEEANKKYDGLQQQLSSVERELENKRRL----------------QKQAASSQSATE---- 296
+++ K + LQQ+L + +L+N+R+L +++ SS+ A E
Sbjct: 1422 YDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Query: 297 -----------VRLNRALEEAEKYKLELSK----LRQNNKDIANEEH---KKIEVLKSEN 338
+ L RALEEA + K EL + L+ +D+ + + K + L+
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 339 KKLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
+ LE Q E+ ++ + + K+ +E
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLE 1573
Score = 50.8 bits (120), Expect = 2e-06
Identities = 80/352 (22%), Positives = 145/352 (41%), Gaps = 41/352 (11%)
Query: 35 LEEEYKR---LNAE---LQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLR 88
LEEE R L AE + + D+ +Q +E RQ+++ V+ + K ED+
Sbjct: 938 LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI--- 994
Query: 89 GLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAI 148
L+ + L E K + I + + A + K + KLK ++ +
Sbjct: 995 -LVMDDQNNKLSKERKLLEERISDLTT-----NLAEEEEKAKNLTKLKNKHESMISELEV 1048
Query: 149 ---PEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQ 205
E+ S L K K+EG + E I D+ +AQI LK +L +
Sbjct: 1049 RLKKEEKSRQELEKLKRKLEGDASD--FHEQIADL----------QAQIAELKMQLAKKE 1096
Query: 206 EELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYD 265
EEL + + +DEI + +K E + I+ Q ++ + +A K+
Sbjct: 1097 EELQAALA---RLDDEIAQKNNALKKIRE----LEGHISDLQEDLDSERAARNKAEKQKR 1149
Query: 266 GLQQQLSSVERELEN---KRRLQKQAASSQSATEVRLNRAL-EEAEKYKLELSKLRQNNK 321
L ++L +++ ELE+ Q++ + + L +AL EE ++ ++ ++RQ +
Sbjct: 1150 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1209
Query: 322 DIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAK 373
E +++E K L+K K L + VL + K +E K
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKK 1261
Score = 46.2 bits (108), Expect = 5e-05
Identities = 79/398 (19%), Positives = 163/398 (40%), Gaps = 83/398 (20%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRS---------RPVSTQMKSCDD 81
+ L +EE +R N L+A+ D+V ++ ++ E+ + TQ++ +D
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560
Query: 82 E----DDYSLR---GLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHS-------ANKGR 127
E +D LR + +G + + + +N + ++Q +LH K R
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDE-QNEEKRRQLQRQLHEYETELEDERKQR 1619
Query: 128 KTNSSVKLKYS----DVQTADDVAIPEDFSDFSLAKTISKIEGQLEE-----EGLPEYID 178
++ K K D++ D AI K + K++ Q+++ E D
Sbjct: 1620 ALAAAAKKKLEGDLKDLELQADSAIK---GREEAIKQLRKLQAQMKDFQRELEDARASRD 1676
Query: 179 DIFSGVSNDIGTEAQIRFLKAKLHVMQE---------------------ELDNVVCECNK 217
+IF+ + E + + L+A L +QE EL + + N
Sbjct: 1677 EIFATAKEN---EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1733
Query: 218 KEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEAN----------KKYDGL 267
+DE + L++++ EE+ +Q + +V K E+ + +K +
Sbjct: 1734 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1793
Query: 268 QQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEE 327
+QQL +EL +K + A S+ + + ALE ++++L + + A E+
Sbjct: 1794 RQQLERQNKELRSKLHEMEGAVKSKFKSTI---AALE------AKIAQLEEQVEQEAREK 1844
Query: 328 HKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQ 365
+ LK ++KKL+ E+++ + + K+ + K Q
Sbjct: 1845 QAATKSLKQKDKKLK----EILLQVEDERKMAEQYKEQ 1878
Score = 42.7 bits (99), Expect = 6e-04
Identities = 74/370 (20%), Positives = 154/370 (41%), Gaps = 55/370 (14%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSE 94
L EE L +LQA+T E+ + +E+R R + + + + + R +
Sbjct: 892 LTEEKNLLQEQLQAET--------ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED 943
Query: 95 GIVHLHSETKPKTKNIDPVNKVQNKLHSANKG---RKTNSSVKLKYSDVQTADDVAIPED 151
L +E K + + + + + +A + K + K+K + D++ + +D
Sbjct: 944 RGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK----KLEDEILVMDD 999
Query: 152 FSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNV 211
++ +SK E + L E I D+ + ++ + + LK K M EL+
Sbjct: 1000 QNN-----KLSK-----ERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049
Query: 212 VCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQL 271
+ + K E++ LK +++ DF Q I Q+Q+ + K + KK + LQ L
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQ---IADLQAQIAELKM---QLAKKEEELQAAL 1103
Query: 272 SSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKI 331
+ ++ E+ K K+ E ++ E+ + + +K + +D+ E +
Sbjct: 1104 ARLDDEIAQKNNALKKIRE----LEGHISDLQEDLDSERAARNKAEKQKRDLGEE----L 1155
Query: 332 EVLKSE----------NKKLEKQKGELMIGFKKQL------KLIDVLKRQKMHIEAAKML 375
E LK+E ++L ++ + + KK L V + ++ H +A + L
Sbjct: 1156 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 376 SFTEEEFMKA 385
+ E+F +A
Sbjct: 1216 TEQLEQFKRA 1225
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/295 (22%), Positives = 126/295 (42%), Gaps = 47/295 (15%)
Query: 106 KTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSD-VQTADDVAIPEDFSDFSLAKTISKI 164
+TK + ++ L + + +TN +K + D V + DDV + L K+ +
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK----NVHELEKSKRAL 1544
Query: 165 EGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEI 222
E Q+EE L E D++ + + E ++ LK + + D + E++
Sbjct: 1545 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE------QNEEKR 1598
Query: 223 QNLKSQVKNFEEDFM--RQQRTI----------NMQQSQVEKYKTLF--EEANKKYDGLQ 268
+ L+ Q+ +E + R+QR + +++ +++ + EEA K+ LQ
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 269 QQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEH 328
Q+ +RELE+ R + + ++ A E +K K + L Q +D+A E
Sbjct: 1659 AQMKDFQRELEDARASRDEIFAT----------AKENEKKAKSLEADLMQLQEDLAAAER 1708
Query: 329 KKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEA--AKMLSFTEEE 381
+ K+ + +K EL L + L+ +K +EA A++ EEE
Sbjct: 1709 AR--------KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1755
Score = 40.0 bits (92), Expect = 0.004
Identities = 73/339 (21%), Positives = 145/339 (42%), Gaps = 62/339 (18%)
Query: 35 LEEEYKR------LNAELQAKTADVVQQAKEIIRDRQEV--RSRPVSTQMKSCDDEDDYS 86
LE+E K+ +L+ D+ QA I+ R+E + R + QMK E + +
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Query: 87 LRGLLPSEGIVHLHSETKPKTKNIDP-VNKVQNKLHSANKGRKTNSSVKLKYSDVQTADD 145
+ I E + K K+++ + ++Q L +A + RK K + ++ + A
Sbjct: 1672 RAS---RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE-ELASS 1727
Query: 146 VAIPEDFSDFS--LAKTISKIEGQLEEE-GLPEYIDDIF-------SGVSNDIGTEA--- 192
++ D L I+++E +LEEE G E + D +SN++ TE
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1787
Query: 193 ------------QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQ 240
Q + L++KLH M+ + + K + I L++++ EE ++
Sbjct: 1788 QKNESARQQLERQNKELRSKLHEMEGAVKS------KFKSTIAALEAKIAQLEEQVEQEA 1841
Query: 241 R-----TINMQQS---------QVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQK 286
R T +++Q QVE + + E+ ++ + ++ ++R+LE +
Sbjct: 1842 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1901
Query: 287 QAASSQSATEVRLNRALEEAEKYKLEL----SKLRQNNK 321
+ +++ + L+ A E E E+ SKLR+ N+
Sbjct: 1902 RINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1940
Score = 38.5 bits (88), Expect = 0.011
Identities = 42/165 (25%), Positives = 75/165 (45%), Gaps = 21/165 (12%)
Query: 193 QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEK 252
Q+ + ++ ++EL K E+E++ L+ + E+ N+ Q Q++
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-------KNLLQEQLQA 905
Query: 253 YKTLFEEANK-------KYDGLQQQLSSVERELENK--RRLQKQAASSQSATE-VRLNRA 302
L+ EA + K L++ L +E LE + R Q QA + A + + L
Sbjct: 906 ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 965
Query: 303 LEEAE--KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQK 345
LEE E + KL+L K+ K E+ +I V+ +N KL K++
Sbjct: 966 LEEEEAARQKLQLEKVTAEAKIKKLED--EILVMDDQNNKLSKER 1008
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 58.9 bits (141), Expect = 8e-09
Identities = 78/392 (19%), Positives = 165/392 (42%), Gaps = 62/392 (15%)
Query: 34 ALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEV-RSRPVSTQMKSCDDEDDYSLRGLLP 92
AL+EE + A++Q Q +E+ ++ R++ + K ++++ L G L
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1248
Query: 93 SEGIVHLHSETKPKTKNIDP-VNKVQNKLHSANKGR-KTNSSVKLKYSDVQTADDVAIPE 150
G E + K K ++ V ++Q+K + R + N V ++V++ +
Sbjct: 1249 VLG--QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1306
Query: 151 DFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDN 210
+ LAK ++ + QL++ E + + + ++R L+ + + +Q++LD
Sbjct: 1307 EGKAIKLAKDVASLSSQLQDT--QELLQE---ETRQKLNVSTKLRQLEEERNSLQDQLDE 1361
Query: 211 VV--------------CECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTL 256
+ + + + ++Q+ S V+ EE R Q+ I Q E+
Sbjct: 1362 EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1421
Query: 257 FEEANKKYDGLQQQLSSVERELENKRRL----------------QKQAASSQSATE---- 296
+++ K + LQQ+L + +L+N+R+L +++ SS+ A E
Sbjct: 1422 YDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Query: 297 -----------VRLNRALEEAEKYKLELSK----LRQNNKDIANEEH---KKIEVLKSEN 338
+ L RALEEA + K EL + L+ +D+ + + K + L+
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 339 KKLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
+ LE Q E+ ++ + + K+ +E
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLE 1573
Score = 50.8 bits (120), Expect = 2e-06
Identities = 80/352 (22%), Positives = 145/352 (41%), Gaps = 41/352 (11%)
Query: 35 LEEEYKR---LNAE---LQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLR 88
LEEE R L AE + + D+ +Q +E RQ+++ V+ + K ED+
Sbjct: 938 LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI--- 994
Query: 89 GLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAI 148
L+ + L E K + I + + A + K + KLK ++ +
Sbjct: 995 -LVMDDQNNKLSKERKLLEERISDLTT-----NLAEEEEKAKNLTKLKNKHESMISELEV 1048
Query: 149 ---PEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQ 205
E+ S L K K+EG + E I D+ +AQI LK +L +
Sbjct: 1049 RLKKEEKSRQELEKLKRKLEGDASD--FHEQIADL----------QAQIAELKMQLAKKE 1096
Query: 206 EELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYD 265
EEL + + +DEI + +K E + I+ Q ++ + +A K+
Sbjct: 1097 EELQAALA---RLDDEIAQKNNALKKIRE----LEGHISDLQEDLDSERAARNKAEKQKR 1149
Query: 266 GLQQQLSSVERELEN---KRRLQKQAASSQSATEVRLNRAL-EEAEKYKLELSKLRQNNK 321
L ++L +++ ELE+ Q++ + + L +AL EE ++ ++ ++RQ +
Sbjct: 1150 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1209
Query: 322 DIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAK 373
E +++E K L+K K L + VL + K +E K
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKK 1261
Score = 46.2 bits (108), Expect = 5e-05
Identities = 79/398 (19%), Positives = 163/398 (40%), Gaps = 83/398 (20%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRS---------RPVSTQMKSCDD 81
+ L +EE +R N L+A+ D+V ++ ++ E+ + TQ++ +D
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560
Query: 82 E----DDYSLR---GLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHS-------ANKGR 127
E +D LR + +G + + + +N + ++Q +LH K R
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDE-QNEEKRRQLQRQLHEYETELEDERKQR 1619
Query: 128 KTNSSVKLKYS----DVQTADDVAIPEDFSDFSLAKTISKIEGQLEE-----EGLPEYID 178
++ K K D++ D AI K + K++ Q+++ E D
Sbjct: 1620 ALAAAAKKKLEGDLKDLELQADSAIK---GREEAIKQLRKLQAQMKDFQRELEDARASRD 1676
Query: 179 DIFSGVSNDIGTEAQIRFLKAKLHVMQE---------------------ELDNVVCECNK 217
+IF+ + E + + L+A L +QE EL + + N
Sbjct: 1677 EIFATAKEN---EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1733
Query: 218 KEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEAN----------KKYDGL 267
+DE + L++++ EE+ +Q + +V K E+ + +K +
Sbjct: 1734 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1793
Query: 268 QQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEE 327
+QQL +EL +K + A S+ + + ALE ++++L + + A E+
Sbjct: 1794 RQQLERQNKELRSKLHEMEGAVKSKFKSTI---AALE------AKIAQLEEQVEQEAREK 1844
Query: 328 HKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQ 365
+ LK ++KKL+ E+++ + + K+ + K Q
Sbjct: 1845 QAATKSLKQKDKKLK----EILLQVEDERKMAEQYKEQ 1878
Score = 42.7 bits (99), Expect = 6e-04
Identities = 74/370 (20%), Positives = 154/370 (41%), Gaps = 55/370 (14%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSE 94
L EE L +LQA+T E+ + +E+R R + + + + + R +
Sbjct: 892 LTEEKNLLQEQLQAET--------ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED 943
Query: 95 GIVHLHSETKPKTKNIDPVNKVQNKLHSANKG---RKTNSSVKLKYSDVQTADDVAIPED 151
L +E K + + + + + +A + K + K+K + D++ + +D
Sbjct: 944 RGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK----KLEDEILVMDD 999
Query: 152 FSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNV 211
++ +SK E + L E I D+ + ++ + + LK K M EL+
Sbjct: 1000 QNN-----KLSK-----ERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049
Query: 212 VCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQL 271
+ + K E++ LK +++ DF Q I Q+Q+ + K + KK + LQ L
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQ---IADLQAQIAELKM---QLAKKEEELQAAL 1103
Query: 272 SSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKI 331
+ ++ E+ K K+ E ++ E+ + + +K + +D+ E +
Sbjct: 1104 ARLDDEIAQKNNALKKIRE----LEGHISDLQEDLDSERAARNKAEKQKRDLGEE----L 1155
Query: 332 EVLKSE----------NKKLEKQKGELMIGFKKQL------KLIDVLKRQKMHIEAAKML 375
E LK+E ++L ++ + + KK L V + ++ H +A + L
Sbjct: 1156 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 376 SFTEEEFMKA 385
+ E+F +A
Sbjct: 1216 TEQLEQFKRA 1225
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/295 (22%), Positives = 126/295 (42%), Gaps = 47/295 (15%)
Query: 106 KTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSD-VQTADDVAIPEDFSDFSLAKTISKI 164
+TK + ++ L + + +TN +K + D V + DDV + L K+ +
Sbjct: 1489 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK----NVHELEKSKRAL 1544
Query: 165 EGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEI 222
E Q+EE L E D++ + + E ++ LK + + D + E++
Sbjct: 1545 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE------QNEEKR 1598
Query: 223 QNLKSQVKNFEEDFM--RQQRTI----------NMQQSQVEKYKTLF--EEANKKYDGLQ 268
+ L+ Q+ +E + R+QR + +++ +++ + EEA K+ LQ
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 269 QQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEH 328
Q+ +RELE+ R + + ++ A E +K K + L Q +D+A E
Sbjct: 1659 AQMKDFQRELEDARASRDEIFAT----------AKENEKKAKSLEADLMQLQEDLAAAER 1708
Query: 329 KKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEA--AKMLSFTEEE 381
+ K+ + +K EL L + L+ +K +EA A++ EEE
Sbjct: 1709 AR--------KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1755
Score = 38.5 bits (88), Expect = 0.011
Identities = 42/165 (25%), Positives = 75/165 (45%), Gaps = 21/165 (12%)
Query: 193 QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEK 252
Q+ + ++ ++EL K E+E++ L+ + E+ N+ Q Q++
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-------KNLLQEQLQA 905
Query: 253 YKTLFEEANK-------KYDGLQQQLSSVERELENK--RRLQKQAASSQSATE-VRLNRA 302
L+ EA + K L++ L +E LE + R Q QA + A + + L
Sbjct: 906 ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 965
Query: 303 LEEAE--KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQK 345
LEE E + KL+L K+ K E+ +I V+ +N KL K++
Sbjct: 966 LEEEEAARQKLQLEKVTAEAKIKKLED--EILVMDDQNNKLSKER 1008
Score = 38.1 bits (87), Expect = 0.014
Identities = 69/331 (20%), Positives = 141/331 (42%), Gaps = 58/331 (17%)
Query: 35 LEEEYKR------LNAELQAKTADVVQQAKEIIRDRQEV--RSRPVSTQMKSCDDEDDYS 86
LE+E K+ +L+ D+ QA I+ R+E + R + QMK E + +
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Query: 87 LRGLLPSEGIVHLHSETKPKTKNIDP-VNKVQNKLHSANKGRKTNSSVKLKYSDVQTADD 145
+ I E + K K+++ + ++Q L +A + RK K + ++ + A
Sbjct: 1672 RAS---RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE-ELASS 1727
Query: 146 VAIPEDFSDFS--LAKTISKIEGQLEEE-GLPEYIDDIF-------SGVSNDIGTEA--- 192
++ D L I+++E +LEEE G E + D +SN++ TE
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1787
Query: 193 ------------QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQ 240
Q + L++KLH M+ + + K + I L++++ EE ++
Sbjct: 1788 QKNESARQQLERQNKELRSKLHEMEGAVKS------KFKSTIAALEAKIAQLEEQVEQEA 1841
Query: 241 R-----TINMQQS---------QVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQK 286
R T +++Q QVE + + E+ ++ + ++ ++R+LE +
Sbjct: 1842 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1901
Query: 287 QAASSQSATEVRLNRALEEAEKYKLELSKLR 317
+ +++ + L+ A E E E++ L+
Sbjct: 1902 RINANRRKLQRELDEATESNEAMGREVNALK 1932
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 58.9 bits (141), Expect = 8e-09
Identities = 78/392 (19%), Positives = 165/392 (42%), Gaps = 62/392 (15%)
Query: 34 ALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEV-RSRPVSTQMKSCDDEDDYSLRGLLP 92
AL+EE + A++Q Q +E+ ++ R++ + K ++++ L G L
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1241
Query: 93 SEGIVHLHSETKPKTKNIDP-VNKVQNKLHSANKGR-KTNSSVKLKYSDVQTADDVAIPE 150
G E + K K ++ V ++Q+K + R + N V ++V++ +
Sbjct: 1242 VLG--QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEA 1299
Query: 151 DFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDN 210
+ LAK ++ + QL++ E + + + ++R L+ + + +Q++LD
Sbjct: 1300 EGKAIKLAKDVASLSSQLQDT--QELLQE---ETRQKLNVSTKLRQLEEERNSLQDQLDE 1354
Query: 211 VV--------------CECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTL 256
+ + + + ++Q+ S V+ EE R Q+ I Q E+
Sbjct: 1355 EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAA 1414
Query: 257 FEEANKKYDGLQQQLSSVERELENKRRL----------------QKQAASSQSATE---- 296
+++ K + LQQ+L + +L+N+R+L +++ SS+ A E
Sbjct: 1415 YDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Query: 297 -----------VRLNRALEEAEKYKLELSK----LRQNNKDIANEEH---KKIEVLKSEN 338
+ L RALEEA + K EL + L+ +D+ + + K + L+
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 339 KKLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
+ LE Q E+ ++ + + K+ +E
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLE 1566
Score = 50.8 bits (120), Expect = 2e-06
Identities = 80/352 (22%), Positives = 145/352 (41%), Gaps = 41/352 (11%)
Query: 35 LEEEYKR---LNAE---LQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLR 88
LEEE R L AE + + D+ +Q +E RQ+++ V+ + K ED+
Sbjct: 931 LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI--- 987
Query: 89 GLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAI 148
L+ + L E K + I + + A + K + KLK ++ +
Sbjct: 988 -LVMDDQNNKLSKERKLLEERISDLTT-----NLAEEEEKAKNLTKLKNKHESMISELEV 1041
Query: 149 ---PEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQ 205
E+ S L K K+EG + E I D+ +AQI LK +L +
Sbjct: 1042 RLKKEEKSRQELEKLKRKLEGDASD--FHEQIADL----------QAQIAELKMQLAKKE 1089
Query: 206 EELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYD 265
EEL + + +DEI + +K E + I+ Q ++ + +A K+
Sbjct: 1090 EELQAALA---RLDDEIAQKNNALKKIRE----LEGHISDLQEDLDSERAARNKAEKQKR 1142
Query: 266 GLQQQLSSVERELEN---KRRLQKQAASSQSATEVRLNRAL-EEAEKYKLELSKLRQNNK 321
L ++L +++ ELE+ Q++ + + L +AL EE ++ ++ ++RQ +
Sbjct: 1143 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1202
Query: 322 DIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAK 373
E +++E K L+K K L + VL + K +E K
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKK 1254
Score = 46.2 bits (108), Expect = 5e-05
Identities = 79/398 (19%), Positives = 163/398 (40%), Gaps = 83/398 (20%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRS---------RPVSTQMKSCDD 81
+ L +EE +R N L+A+ D+V ++ ++ E+ + TQ++ +D
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
Query: 82 E----DDYSLR---GLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHS-------ANKGR 127
E +D LR + +G + + + +N + ++Q +LH K R
Sbjct: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDE-QNEEKRRQLQRQLHEYETELEDERKQR 1612
Query: 128 KTNSSVKLKYS----DVQTADDVAIPEDFSDFSLAKTISKIEGQLEE-----EGLPEYID 178
++ K K D++ D AI K + K++ Q+++ E D
Sbjct: 1613 ALAAAAKKKLEGDLKDLELQADSAIK---GREEAIKQLRKLQAQMKDFQRELEDARASRD 1669
Query: 179 DIFSGVSNDIGTEAQIRFLKAKLHVMQE---------------------ELDNVVCECNK 217
+IF+ + E + + L+A L +QE EL + + N
Sbjct: 1670 EIFATAKEN---EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1726
Query: 218 KEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEAN----------KKYDGL 267
+DE + L++++ EE+ +Q + +V K E+ + +K +
Sbjct: 1727 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESA 1786
Query: 268 QQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEE 327
+QQL +EL +K + A S+ + + ALE ++++L + + A E+
Sbjct: 1787 RQQLERQNKELRSKLHEMEGAVKSKFKSTI---AALE------AKIAQLEEQVEQEAREK 1837
Query: 328 HKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQ 365
+ LK ++KKL+ E+++ + + K+ + K Q
Sbjct: 1838 QAATKSLKQKDKKLK----EILLQVEDERKMAEQYKEQ 1871
Score = 42.7 bits (99), Expect = 6e-04
Identities = 74/370 (20%), Positives = 154/370 (41%), Gaps = 55/370 (14%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSE 94
L EE L +LQA+T E+ + +E+R R + + + + + R +
Sbjct: 885 LTEEKNLLQEQLQAET--------ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEED 936
Query: 95 GIVHLHSETKPKTKNIDPVNKVQNKLHSANKG---RKTNSSVKLKYSDVQTADDVAIPED 151
L +E K + + + + + +A + K + K+K + D++ + +D
Sbjct: 937 RGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK----KLEDEILVMDD 992
Query: 152 FSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNV 211
++ +SK E + L E I D+ + ++ + + LK K M EL+
Sbjct: 993 QNN-----KLSK-----ERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
Query: 212 VCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQL 271
+ + K E++ LK +++ DF Q I Q+Q+ + K + KK + LQ L
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQ---IADLQAQIAELKM---QLAKKEEELQAAL 1096
Query: 272 SSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKI 331
+ ++ E+ K K+ E ++ E+ + + +K + +D+ E +
Sbjct: 1097 ARLDDEIAQKNNALKKIRE----LEGHISDLQEDLDSERAARNKAEKQKRDLGEE----L 1148
Query: 332 EVLKSE----------NKKLEKQKGELMIGFKKQL------KLIDVLKRQKMHIEAAKML 375
E LK+E ++L ++ + + KK L V + ++ H +A + L
Sbjct: 1149 EALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1208
Query: 376 SFTEEEFMKA 385
+ E+F +A
Sbjct: 1209 TEQLEQFKRA 1218
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/295 (22%), Positives = 126/295 (42%), Gaps = 47/295 (15%)
Query: 106 KTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSD-VQTADDVAIPEDFSDFSLAKTISKI 164
+TK + ++ L + + +TN +K + D V + DDV + L K+ +
Sbjct: 1482 ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGK----NVHELEKSKRAL 1537
Query: 165 EGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEI 222
E Q+EE L E D++ + + E ++ LK + + D + E++
Sbjct: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE------QNEEKR 1591
Query: 223 QNLKSQVKNFEEDFM--RQQRTI----------NMQQSQVEKYKTLF--EEANKKYDGLQ 268
+ L+ Q+ +E + R+QR + +++ +++ + EEA K+ LQ
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 269 QQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEH 328
Q+ +RELE+ R + + ++ A E +K K + L Q +D+A E
Sbjct: 1652 AQMKDFQRELEDARASRDEIFAT----------AKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 329 KKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEA--AKMLSFTEEE 381
+ K+ + +K EL L + L+ +K +EA A++ EEE
Sbjct: 1702 AR--------KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1748
Score = 38.5 bits (88), Expect = 0.011
Identities = 42/165 (25%), Positives = 75/165 (45%), Gaps = 21/165 (12%)
Query: 193 QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEK 252
Q+ + ++ ++EL K E+E++ L+ + E+ N+ Q Q++
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEE-------KNLLQEQLQA 898
Query: 253 YKTLFEEANK-------KYDGLQQQLSSVERELENK--RRLQKQAASSQSATE-VRLNRA 302
L+ EA + K L++ L +E LE + R Q QA + A + + L
Sbjct: 899 ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 958
Query: 303 LEEAE--KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQK 345
LEE E + KL+L K+ K E+ +I V+ +N KL K++
Sbjct: 959 LEEEEAARQKLQLEKVTAEAKIKKLED--EILVMDDQNNKLSKER 1001
Score = 38.1 bits (87), Expect = 0.014
Identities = 69/331 (20%), Positives = 141/331 (42%), Gaps = 58/331 (17%)
Query: 35 LEEEYKR------LNAELQAKTADVVQQAKEIIRDRQEV--RSRPVSTQMKSCDDEDDYS 86
LE+E K+ +L+ D+ QA I+ R+E + R + QMK E + +
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Query: 87 LRGLLPSEGIVHLHSETKPKTKNIDP-VNKVQNKLHSANKGRKTNSSVKLKYSDVQTADD 145
+ I E + K K+++ + ++Q L +A + RK K + ++ + A
Sbjct: 1665 RAS---RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE-ELASS 1720
Query: 146 VAIPEDFSDFS--LAKTISKIEGQLEEE-GLPEYIDDIF-------SGVSNDIGTEA--- 192
++ D L I+++E +LEEE G E + D +SN++ TE
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1780
Query: 193 ------------QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQ 240
Q + L++KLH M+ + + K + I L++++ EE ++
Sbjct: 1781 QKNESARQQLERQNKELRSKLHEMEGAVKS------KFKSTIAALEAKIAQLEEQVEQEA 1834
Query: 241 R-----TINMQQS---------QVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQK 286
R T +++Q QVE + + E+ ++ + ++ ++R+LE +
Sbjct: 1835 REKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQ 1894
Query: 287 QAASSQSATEVRLNRALEEAEKYKLELSKLR 317
+ +++ + L+ A E E E++ L+
Sbjct: 1895 RINANRRKLQRELDEATESNEAMGREVNALK 1925
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 58.5 bits (140), Expect = 1e-08
Identities = 74/362 (20%), Positives = 153/362 (42%), Gaps = 45/362 (12%)
Query: 32 LLALEEEYKRLNAELQAKTADVVQQAKEIIR--DRQEVRSRPVSTQMKSCDDEDDYSLRG 89
+L LE+ K L +LQ + + +++ KE+ + ++++ S + ++ S ++ +
Sbjct: 887 ILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNT 946
Query: 90 LLPSE--------GIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQ 141
L +E I L ++ K K I+ + Q +L A +KT KL+ Q
Sbjct: 947 LKQNEKEEQQLQGNINELKQSSEQKKKQIEAL---QGELKIAVL-QKTELENKLQQQLTQ 1002
Query: 142 TADDVAIPEDFSDFSLAKTISKIEGQLE--EEGLPEYIDDIFSGVSNDIGTEAQIRFLKA 199
A ++A ++ IS ++ E +E + D + S + T ++ ++
Sbjct: 1003 AAQELAAEKE--------KISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEE 1054
Query: 200 KLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEE 259
KL + QE+L + + + IQ LK+ E+D ++++ + +E
Sbjct: 1055 KLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQL--------------QE 1100
Query: 260 ANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQN 319
K +Q++ S E+EL N++ + + E + + EE + +KLE K N
Sbjct: 1101 RCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITN 1160
Query: 320 NKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTE 379
KD ++L + +L+ + L +++ + +LK Q E F E
Sbjct: 1161 LKDAK-------QLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIE 1213
Query: 380 EE 381
+E
Sbjct: 1214 KE 1215
Score = 50.8 bits (120), Expect = 2e-06
Identities = 66/314 (21%), Positives = 126/314 (40%), Gaps = 27/314 (8%)
Query: 32 LLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDE-DDYSLRGL 90
L A E R++ EL K + Q+ KE + + E + + + + K + ++ GL
Sbjct: 353 LSASETSLHRIHVELSEK-GEATQKLKEELSE-VETKYQHLKAEFKQLQQQREEKEQHGL 410
Query: 91 LPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPE 150
I LHS+ + + + H K ++ SS KL + Q AD
Sbjct: 411 QLQSEINQLHSKLLETERQL-------GEAHGRLKEQRQLSSEKLMDKEQQVAD------ 457
Query: 151 DFSDFSLAKTISKIEGQLEEE--GLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEEL 208
L +S++E QL+E+ E + +A + AKL Q +L
Sbjct: 458 ------LQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDL 511
Query: 209 DNVVCECNKKEDEIQNLKSQVKNFEEDFM---RQQRTINMQQSQVEKYKTLFEEANKKYD 265
+ V+ + K+ +IQNL++ ++ +E+ +++ + + E + + +K
Sbjct: 512 EQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNH 571
Query: 266 GLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIAN 325
LQ+Q++ + +L+N+ KQA + L A+ L L N
Sbjct: 572 TLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLN 631
Query: 326 EEHKKIEVLKSENK 339
E +K+ L + K
Sbjct: 632 ESKEKVSQLDIQIK 645
Score = 46.6 bits (109), Expect = 4e-05
Identities = 73/330 (22%), Positives = 136/330 (41%), Gaps = 51/330 (15%)
Query: 37 EEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGI 96
+EYK L+ KT ++ Q K++ D EV++ S + D + L
Sbjct: 712 KEYKEKYLSLEQKTEELEGQIKKLEADSLEVKA---SKEQALQDLQQQRQLN-------- 760
Query: 97 VHLHSETKPKTKNIDPVNKVQNKLH-SANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDF 155
L +K ++ ++ + K + S+K K + Q + + +DF
Sbjct: 761 TDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTK-QEEEKQILKQDF--- 816
Query: 156 SLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCEC 215
+T+S+ E +++ E L I T +++ +K + + EL V +
Sbjct: 817 ---ETLSQ-ETKIQHEELNNRIQT----------TVTELQKVKMEKEALMTELSTVKDKL 862
Query: 216 NKKEDEIQNLKSQVKNFEEDFMRQQRTI---------NMQQSQVEKYKTLFEEANKKYDG 266
+K D ++N KS+ FE++ + + I Q QV+ TL E+ K
Sbjct: 863 SKVSDSLKNSKSE---FEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELK--- 916
Query: 267 LQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANE 326
S+E+E E +L+ + S Q ++ L++ EK + +L K + +
Sbjct: 917 -----KSLEKEKEASHQLKLELNSMQEQL-IQAQNTLKQNEKEEQQLQGNINELKQSSEQ 970
Query: 327 EHKKIEVLKSENKKLEKQKGELMIGFKKQL 356
+ K+IE L+ E K QK EL ++QL
Sbjct: 971 KKKQIEALQGELKIAVLQKTELENKLQQQL 1000
Score = 43.5 bits (101), Expect = 3e-04
Identities = 62/283 (21%), Positives = 116/283 (40%), Gaps = 22/283 (7%)
Query: 115 KVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAI-PEDFSDFSLAKTISKIEGQLEEEGL 173
KV NK +K + +DVA+ ++ +E + E E L
Sbjct: 192 KVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKL 251
Query: 174 PEYIDDIFSGVSNDIGTEAQIRFLKAK----LHVMQEELDNVVCECNKKEDEIQNLKSQV 229
+ + S ++ T +Q+R AK + V +EL + N+ + Q L +
Sbjct: 252 KDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENL 311
Query: 230 KNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAA 289
E+D+ + + N + + + + + LQ +LS+ E L R+ + +
Sbjct: 312 LKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSL---HRIHVELS 368
Query: 290 SSQSATEVRLNRALEEAE-KY---KLELSKLRQNNKDIANEEH-----KKIEVLKSENKK 340
AT+ +L L E E KY K E +L+Q ++ E+H +I L S+ +
Sbjct: 369 EKGEATQ-KLKEELSEVETKYQHLKAEFKQLQQQREE--KEQHGLQLQSEINQLHSKLLE 425
Query: 341 LEKQKGELMIGFKKQLKLID--VLKRQKMHIEAAKMLSFTEEE 381
E+Q GE K+Q +L ++ +++ + LS EE+
Sbjct: 426 TERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQ 468
Score = 42.4 bits (98), Expect = 7e-04
Identities = 68/422 (16%), Positives = 166/422 (39%), Gaps = 70/422 (16%)
Query: 31 DLLALEEEYKRLNAE---LQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSL 87
+L +E +Y+ L AE LQ + + Q ++ + ++ S+ + T+ + +
Sbjct: 380 ELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKE 439
Query: 88 RGLLPSEGIV--------------HLHSETKPKTKNIDPVNKVQNKL---HSANKGRKTN 130
+ L SE ++ L + K K N + +K H + + +
Sbjct: 440 QRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQS 499
Query: 131 SSVKLK--YSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDI 188
++ KL+ +D++ +D +L + K + + L + +D+++ +
Sbjct: 500 TTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISL--LEKEREDLYAKIQAGE 557
Query: 189 GTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQS 248
G A + L+ K H +QE++ + K +++ ++ K +N + Q+ + Q
Sbjct: 558 GETAVLNQLQEKNHTLQEQVTQLT---EKLKNQSESHKQAQENLHDQVQEQKAHLRAAQD 614
Query: 249 QVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAE- 307
+V +T E N + + ++++S ++ +++ K L A ++++A L L+ A+
Sbjct: 615 RVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQN 674
Query: 308 --------------------------------------KYKLELSKLRQNNKDIANE--- 326
+YK + L Q +++ +
Sbjct: 675 ALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKK 734
Query: 327 -EHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFMKA 385
E +EV S+ + L+ + + + +L+ ++ K+ +M E ++ +A
Sbjct: 735 LEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEA 794
Query: 386 LE 387
LE
Sbjct: 795 LE 796
Score = 41.2 bits (95), Expect = 0.002
Identities = 78/379 (20%), Positives = 156/379 (41%), Gaps = 56/379 (14%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEV-----RSRPVSTQMKSCDDEDDYSLRG 89
L++E K+L ++ + A + Q E+ + QEV + + + + ++
Sbjct: 251 LKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTEN 310
Query: 90 LLPSE----GIVHLHSETKPKTKNIDPV--------NKVQNKLHS------------ANK 125
LL E + H+E KNI ++Q++L + + K
Sbjct: 311 LLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEK 370
Query: 126 GRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVS 185
G T +K + S+V+T E K + + + E+ GL + +I S
Sbjct: 371 GEAT-QKLKEELSEVETKYQHLKAE-------FKQLQQQREEKEQHGL-QLQSEINQLHS 421
Query: 186 NDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQ------ 239
+ TE Q+ +L ++ + + KE ++ +L+ ++ EE +
Sbjct: 422 KLLETERQLGEAHGRLKEQRQLSSEKLMD---KEQQVADLQLKLSRLEEQLKEKVTNSTE 478
Query: 240 -QRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENK-RRLQKQAASSQSATEV 297
Q ++ + Q ++ + L + K Q L V R++ +K +++Q A Q + E
Sbjct: 479 LQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKE- 537
Query: 298 RLNRALEEAEKYKLELSKLRQNNKDIA--NEEHKKIEVLKSENKKL-EKQKGELMIGFKK 354
N +L E E+ L +K++ + A N+ +K L+ + +L EK K + +
Sbjct: 538 --NISLLEKEREDL-YAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQA 594
Query: 355 QLKLIDVLKRQKMHIEAAK 373
Q L D ++ QK H+ AA+
Sbjct: 595 QENLHDQVQEQKAHLRAAQ 613
Score = 37.7 bits (86), Expect = 0.018
Identities = 52/243 (21%), Positives = 99/243 (40%), Gaps = 44/243 (18%)
Query: 111 DPVNKVQNKLHSA--NKGRKTNSSVKLKYSDV----QTADDVAIP---EDFSDFSLAKTI 161
D + K +H A + G S++ LK DV Q D+ E + L K +
Sbjct: 54 DELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKEL 113
Query: 162 SKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDE 221
K +G ++E P+ G+ D E Q ++++L+ + E
Sbjct: 114 EKYQGLQQQEAKPD-------GLVTDSSAELQS---------LEQQLEEA-------QTE 150
Query: 222 IQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENK 281
N+K FE+ + I +S+ ++ ++L E A +K L ++L+ +++
Sbjct: 151 NFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDL 210
Query: 282 RRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKL 341
+ TE+ +E+ K EL +++ ++ E ++ E LK E KKL
Sbjct: 211 K------------TELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKL 258
Query: 342 EKQ 344
+ Q
Sbjct: 259 QSQ 261
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 57.8 bits (138), Expect = 2e-08
Identities = 38/171 (22%), Positives = 82/171 (47%), Gaps = 21/171 (12%)
Query: 200 KLHVMQEELDNVVCECNKKEDEIQNLKSQV-----------KNFEEDFMRQQRTINMQQS 248
KL ++ L N K++ ++ L+ ++ + EE+ Q R + ++++
Sbjct: 311 KLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEEN 370
Query: 249 QVEKYKTLFEEANKKYDGLQQQLSSVER---------ELENKRRLQKQAASSQSATEVRL 299
QV+KY L EEA+K+ L Q+L R +LE +++++ +A Q E+
Sbjct: 371 QVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLREIEE 430
Query: 300 N-RALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELM 349
N + +E+ E+Y + + K + E +++E+ K ++ K+ ++M
Sbjct: 431 NQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVM 481
Score = 43.9 bits (102), Expect = 3e-04
Identities = 54/221 (24%), Positives = 95/221 (42%), Gaps = 28/221 (12%)
Query: 192 AQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTIN---MQQS 248
AQ++ KL+ + E++ + E K EI+ K ++ E++ +++ + +Q
Sbjct: 219 AQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQ 278
Query: 249 QVEK-YKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRA--LEE 305
Q+EK K E N+K Q + + E ++L+ S Q+A + R ++E
Sbjct: 279 QIEKEIKEKDSELNQK---RPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDE 335
Query: 306 AEKYKLELSKLRQ------------NNKDIANEEH--KKIEVLKSENKKLEKQKGELMIG 351
EK L + K RQ +D+ EE+ KK LK E K + +
Sbjct: 336 LEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEK 395
Query: 352 FKKQLKL----IDVLKRQKMHIEAAKMLSFTE-EEFMKALE 387
F + K +D+ +R+K+ EA E EE K +E
Sbjct: 396 FNRDQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIE 436
Score = 39.7 bits (91), Expect = 0.005
Identities = 70/379 (18%), Positives = 145/379 (38%), Gaps = 44/379 (11%)
Query: 36 EEEYKRLNAELQAKTADVVQQAKEI--IRDRQEVRSRPVSTQMKSCDD------EDDYSL 87
E E ++LN EL +K ++ + K + + D + + + + M+ E D L
Sbjct: 232 EVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 88 RGLLPSEGIVHLHSETKPKTKNIDPVNK-VQN--KLHSANKG-----RKTNSSVKLKYSD 139
P + T K K ++ K +QN K + KG K SV+ +
Sbjct: 292 NQKRPQ--YIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQE 349
Query: 140 VQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEY--IDDIFSGVSNDIGTEAQIRFL 197
+ + D +L + K +L+EE + + D + L
Sbjct: 350 FEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDL 409
Query: 198 KAKLHVMQE-ELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTL 256
+ + V E ++ + E + + I+ L+ + ++ Q++ +VE K
Sbjct: 410 EERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRR 469
Query: 257 FEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEV--------RLNRALEEAEK 308
+E NK+ + + +QL + + R Q++A +S + ++ +K
Sbjct: 470 IDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKK 529
Query: 309 YKLELSKLRQNNKDIANEEHKK-----IEVLKSENKKLE----------KQKGELMIGFK 353
Y++ ++K+ N D + +K I+ +K + + E K E + K
Sbjct: 530 YQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELK 589
Query: 354 KQLKLIDVLKRQKMHIEAA 372
+IDV++ + HI+ A
Sbjct: 590 GAKLVIDVIRYEPPHIKKA 608
Score = 38.9 bits (89), Expect = 0.008
Identities = 45/265 (16%), Positives = 108/265 (40%), Gaps = 17/265 (6%)
Query: 99 LHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSS----VKLKYSDVQTADDVAIPEDFSD 154
L + K K K + + +VQ++ H K + S K ++ + + + + ++
Sbjct: 685 LKEQMKAKRKEAE-LRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKSKLESELAN 743
Query: 155 FS-----LAKTISKIEGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEE 207
F + + I E ++++ E + + D++F +IG F + K+ Q E
Sbjct: 744 FGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRNIREFEEEKVK-RQNE 802
Query: 208 LDNVVCECNKKED----EIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKK 263
+ E ++ ++ K+Q+K ++ ++T+ ++++EK K + K
Sbjct: 803 IAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKI 862
Query: 264 YDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDI 323
D QL ++ + K+ +L A +E + E++ + +
Sbjct: 863 IDETMAQLQDLKNQHLAKKSEVNDKNHEMEEIRKKLGGANKEMTHLQKEVTAIETKLEQK 922
Query: 324 ANEEHKKIEVLKSENKKLEKQKGEL 348
++ H ++ K ++ KL KG +
Sbjct: 923 RSDRHNLLQACKMQDIKLPLSKGTM 947
Score = 37.7 bits (86), Expect = 0.018
Identities = 34/171 (19%), Positives = 75/171 (43%), Gaps = 19/171 (11%)
Query: 217 KKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVER 276
++ D Q LK +V + Q + + ++EK NK+ + ++++ VE
Sbjct: 204 EEADRYQRLKDEVVRAQVQL--QLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVED 261
Query: 277 ELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKS 336
EL+ K++ + Q E + E + + + K ++N + + KK+E K
Sbjct: 262 ELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRPQYIKAKEN----TSHKIKKLEAAKK 317
Query: 337 ENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFMKALE 387
+ +K +KK+ +D L+++ + +E A+ +EF + +E
Sbjct: 318 SLQNAQKH-------YKKRKGDMDELEKEMLSVEKAR------QEFEERME 355
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 57.8 bits (138), Expect = 2e-08
Identities = 84/386 (21%), Positives = 161/386 (41%), Gaps = 53/386 (13%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCD-------DED 83
D LA EE L + + + V++ E + D +EV + + + K D D D
Sbjct: 945 DNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDID 1004
Query: 84 DYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKG--RKTNSSVKLKYSDVQ 141
D L L K K + V + ++ + ++ R T L+ + Q
Sbjct: 1005 DLKLT----------LAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQ 1054
Query: 142 TADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSND----IGTEAQIRFL 197
D+ ED ++K + +LE++ ++D+ + + + TE R L
Sbjct: 1055 ALGDLQAEED-----RVSALTKAKLRLEQQ-----VEDLECSLEQEKKLRMDTERAKRKL 1104
Query: 198 KAKLHVMQEELDNVVCE-------CNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQV 250
+ L + QE + + + KK+ E+ L +V++ + + Q+ I Q++
Sbjct: 1105 EGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARA 1164
Query: 251 EKYKTLFEEANKKYDGLQQQLSSVERELEN-KRRLQKQAASSQSATEV---------RLN 300
E+ + E +++Q + RELE RL++ +S E RL
Sbjct: 1165 EELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1224
Query: 301 RALEEAE-KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLI 359
R LEEA +++ ++ LR+ + A E ++++ L+ +KLEK+K EL + +
Sbjct: 1225 RELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV 1284
Query: 360 DVLKRQKMHIEAAKMLSFTEEEFMKA 385
+ L R K A K+ E++ +A
Sbjct: 1285 ETLTRAK--ASAEKLCRTYEDQLSEA 1308
Score = 53.5 bits (127), Expect = 3e-07
Identities = 63/302 (20%), Positives = 130/302 (43%), Gaps = 33/302 (10%)
Query: 37 EEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSR----PVSTQMKSCDDEDDYSLRGLLP 92
+E +RL AEL + + ++A + + +E+R+ S ++ + + LL
Sbjct: 1707 DEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLH 1766
Query: 93 SEGIVHLHSETKPKTKNIDPVNKV----QNKLHSANKGRKTNSSVKLKYSDVQTADDVAI 148
S+ L+ + K + +V Q + + K +K + + +++ D +
Sbjct: 1767 SQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSA 1826
Query: 149 PEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEEL 208
+ +L +T+ +++ +LEE + G EA++R L+A+L Q++
Sbjct: 1827 HLERMKKTLEQTVRELQARLEEAEQAA----LRGGKKQVQKLEAKVRELEAELDAEQKKH 1882
Query: 209 DNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQ 268
+ K E ++ L Q + ++ R Q ++ QS+V+ YK FEEA +
Sbjct: 1883 AEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEA-------E 1935
Query: 269 QQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEH 328
QQ ++ L R+ Q + L+ A E A+ + + +KLR +D +H
Sbjct: 1936 QQANT---NLAKYRKAQHE-----------LDDAEERADMAETQANKLRARTRDALGPKH 1981
Query: 329 KK 330
K+
Sbjct: 1982 KE 1983
Score = 42.7 bits (99), Expect = 6e-04
Identities = 41/176 (23%), Positives = 79/176 (44%), Gaps = 9/176 (5%)
Query: 217 KKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVER 276
++ +E++ K ++ ++ N + S +EK K + ++ ++ +S
Sbjct: 1430 QRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAA 1489
Query: 277 ELENKRRLQKQAASSQSATEVRLNRALEEAEKYK----LELSKLRQNNKDIANEEHKKIE 332
L+ K+R ++A + E + R LE A++ EL +LR ++ E + +E
Sbjct: 1490 ALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHE----EALEALE 1545
Query: 333 VLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKM-LSFTEEEFMKALE 387
LK ENK L+++ +L K I L++ K +E K + EE ALE
Sbjct: 1546 TLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALE 1601
Score = 39.3 bits (90), Expect = 0.006
Identities = 67/358 (18%), Positives = 143/358 (39%), Gaps = 36/358 (10%)
Query: 37 EEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGI 96
E KR N LQ + +D+ Q + QE+ K+ + E L +EG
Sbjct: 1545 ETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTK-----KALEGEKSEIQAALEEAEGA 1599
Query: 97 VHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFS 156
+ L ETK ++ +++V+ ++ K L+ + + + + D +
Sbjct: 1600 LELE-ETKTLRIQLE-LSQVKAEV-DRKLAEKDEECANLRRNHQRAVESLQASLDAETRA 1656
Query: 157 LAKTI---SKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQI--RFLKAKLHVMQ---EEL 208
+ + K+EG L + L G + TEAQ R ++A+L Q +E
Sbjct: 1657 RNEALRLKKKMEGDLNDLELQ-------LGHATRQATEAQAATRLMQAQLKEEQAGRDEE 1709
Query: 209 DNVVCECNKKEDEIQN----LKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKY 264
+ E +++ ++ L ++++ + +R+ + + ++ + + +
Sbjct: 1710 QRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQN 1769
Query: 265 DGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIA 324
GL Q +E +L ++AA + E + +A+ +A EL K + + +
Sbjct: 1770 TGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1829
Query: 325 NEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKR---------QKMHIEAAK 373
+ + ++ +LE+ + + G KKQ++ ++ R QK H EA K
Sbjct: 1830 RMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALK 1887
Score = 37.4 bits (85), Expect = 0.023
Identities = 78/388 (20%), Positives = 156/388 (40%), Gaps = 35/388 (9%)
Query: 34 ALEEEYKRLNAELQAKTA-----DVVQQAKEIIRDR--QEVRSRPVSTQMKSCDDEDDYS 86
+LEE ++L E +AK+A ++ +++R++ +E ++ ++ S + +
Sbjct: 1360 SLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQ 1419
Query: 87 LRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDV 146
R ++ I + K K + + + + +AN K +S K K ++DV
Sbjct: 1420 WRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANA--KCSSLEKAKLRLQTESEDV 1477
Query: 147 AIPEDFSDFSLAKTISK---IEGQLEEEGLPE--YIDDIFSGVSNDIGTEAQIRFLKAKL 201
+ + + + A K +E LEE E ++ + G ++ L+
Sbjct: 1478 TLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGH 1537
Query: 202 HVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEA- 260
E L+ + E ++EI +L QV + ++T + + + + EEA
Sbjct: 1538 EEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAE 1597
Query: 261 ------NKKYDGLQQQLSSVERELENK-----------RRLQKQAASSQSATEVRLNRAL 303
K +Q +LS V+ E++ K RR ++A S A+ RA
Sbjct: 1598 GALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRAR 1657
Query: 304 EEAEKYKLEL-SKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVL 362
EA + K ++ L + + + E ++ + ++ Q E G ++ +L L
Sbjct: 1658 NEALRLKKKMEGDLNDLELQLGHATRQATEA-QAATRLMQAQLKEEQAGRDEEQRLAAEL 1716
Query: 363 KRQKMHIE-AAKMLSFTEEEFMKALEWG 389
Q +E A +L+ EE ALE G
Sbjct: 1717 HEQAQALERRASLLAAELEELRAALEQG 1744
Score = 37.0 bits (84), Expect = 0.031
Identities = 81/353 (22%), Positives = 146/353 (41%), Gaps = 65/353 (18%)
Query: 34 ALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVST-QMKSCDDEDDYSLRGLLP 92
AL+E +++ +LQA+ V K +R Q+V S Q K + + + R L
Sbjct: 1047 ALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKL-- 1104
Query: 93 SEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDF 152
EG + L E+ + Q+K K +K +S +L ++ D E
Sbjct: 1105 -EGDLKLTQESV--------ADAAQDKQQLEEKLKKKDS--ELSQLSLRVED-----EQL 1148
Query: 153 SDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVV 212
+ K I +++ + EE L E ++ + A++ +A+ EEL +
Sbjct: 1149 LGAQMQKKIKELQARAEE--LEEELEA-------ERAARARVEKQRAEAARELEELSERL 1199
Query: 213 CE-----------CNKKEDEIQNLKSQVKNFEEDFMRQQRTIN-MQQSQVEKYKTLFEEA 260
E C K+E E+ L+ ++ EE +R + T+ +++ Q E L E+
Sbjct: 1200 EEAGGASAGQREGCRKREAELGRLRREL---EEAALRHEATVAALRRKQAEGAAELGEQV 1256
Query: 261 NKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNN 320
D LQ+ V ++LE ++ + +A L RA AEK L +
Sbjct: 1257 ----DSLQR----VRQKLEKEKSELRMEVDDLAANVETLTRAKASAEK-------LCRTY 1301
Query: 321 KDIANEEHKKIEVLK-------SENKKLEKQKGELMIGFKKQLKLIDVLKRQK 366
+D +E K+E L+ ++ +L+ + GEL +++ LI L R K
Sbjct: 1302 EDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGK 1354
Score = 36.6 bits (83), Expect = 0.040
Identities = 38/216 (17%), Positives = 87/216 (40%), Gaps = 19/216 (8%)
Query: 191 EAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQV 250
E Q+ K K+ +Q +L + + + + E L ++ E + R + +
Sbjct: 1302 EDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSL 1361
Query: 251 EKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRA-------- 302
E+ + EE +K L + ++ + + R ++ A +Q+ + L++A
Sbjct: 1362 EELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWR 1421
Query: 303 ----------LEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGF 352
EE E+ K +L+ Q ++ + K L+ +L+ + ++ +
Sbjct: 1422 SKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLEL 1481
Query: 353 KKQLKLIDVLKRQKMHIE-AAKMLSFTEEEFMKALE 387
++ L +++ H+E A + EEE + LE
Sbjct: 1482 ERATSAAAALDKKQRHLERALEERRRQEEEMQRELE 1517
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 57.0 bits (136), Expect = 3e-08
Identities = 71/363 (19%), Positives = 154/363 (42%), Gaps = 47/363 (12%)
Query: 54 VQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPV 113
VQ+A +I RD+ + ++ + +MK +++ L+ + +ET+ K I+ +
Sbjct: 1598 VQEALQIERDQLKENTKEIVAKMKESQEKEYQFLK--------MTAVNETQEKMCEIEHL 1649
Query: 114 NKVQNKLHSANKGRKTNSSVKLKYSDVQTADDV-AIPEDFSDFSLAKTISKIEGQLEEEG 172
K Q + N +++L + +++ ++ ++ D + K+E +E
Sbjct: 1650 -KEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKEN 1708
Query: 173 LPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQN-------- 224
L E I + D+ + +++ + L QE +D + ++K +EI N
Sbjct: 1709 LRETI-------TRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHS 1761
Query: 225 ---LKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENK 281
LK+Q +E+ + QQ ++K + + E K +Q+ L + +L+ K
Sbjct: 1762 NDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEK 1821
Query: 282 RR-----------LQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKK 330
+ L+K +Q + + ++ + L LSKL N ++A + H+
Sbjct: 1822 IQELKANEHQLITLKKDVNETQKKVS-EMEQLKKQIKDQSLTLSKLEIENLNLAQKLHEN 1880
Query: 331 IEVLKS---ENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIE----AAKMLSFTEEEFM 383
+E +KS E L + + L + + + + K + + I+ A+MLS +E +
Sbjct: 1881 LEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETV 1940
Query: 384 KAL 386
L
Sbjct: 1941 DKL 1943
Score = 50.1 bits (118), Expect = 3e-06
Identities = 44/215 (20%), Positives = 94/215 (43%), Gaps = 25/215 (11%)
Query: 193 QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEK 252
+I+ +LH++ E D + E KE +Q L ++ ++D Q + +
Sbjct: 762 EIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQN 821
Query: 253 YKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLE 312
+KTL + +KY + ++ + +E+ N + ++ SS A + L+ +E ++ E
Sbjct: 822 FKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTRE 881
Query: 313 ----LSKLRQNNKDIANEEH-------------KKIEVLKSENKKLEKQKGELMIGFKKQ 355
L+++ Q + + N + +K++ E K L ++K +L KQ
Sbjct: 882 VQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDL-----KQ 936
Query: 356 LKLIDVLKRQKMHI---EAAKMLSFTEEEFMKALE 387
L+ ++R ++ + M T+E+ ALE
Sbjct: 937 LQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALE 971
Score = 47.0 bits (110), Expect = 3e-05
Identities = 67/320 (20%), Positives = 144/320 (45%), Gaps = 35/320 (10%)
Query: 33 LALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDD-YSLRGLL 91
L +EE K ++ L+ Q+ + +R ++ +S K + +D + L
Sbjct: 1717 LEKQEELKIVHMHLKEH-----QETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLK 1771
Query: 92 PSEGIVHLHSETKPKTKNIDP----VNKVQNKLHSANKG-RKTNSSVKLKYSDVQTADDV 146
E + H K + + ID V++ +KL + K +N+ ++ K +++ +
Sbjct: 1772 IQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQ 1831
Query: 147 AIPEDFSDFSLAKTISKIEGQLEE-EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQ 205
I +L K +++ + ++ E E L + I D +S E + L KLH
Sbjct: 1832 LI-------TLKKDVNETQKKVSEMEQLKKQIKDQSLTLSK---LEIENLNLAQKLHENL 1881
Query: 206 EELDNVVCECNKKEDEIQNLKSQVKNFEEDFMR-QQRTINMQQSQVEKYKTLFEEANKKY 264
EE+ +V+ E + + LK + +E + R + +QQ +++ + L +E +
Sbjct: 1882 EEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQ-ELKTARMLSKEHKETV 1940
Query: 265 DGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIA 324
D L++++S ++ + +QK S+ L + ++E +K +L+L +++++
Sbjct: 1941 DKLREKISEKTIQISD---IQKDLDKSKD----ELQKKIQELQKKELQLLRVKED----V 1989
Query: 325 NEEHKKIEVLKSENKKLEKQ 344
N HKKI ++ K+ E Q
Sbjct: 1990 NMSHKKINEMEQLKKQFEAQ 2009
Score = 42.4 bits (98), Expect = 7e-04
Identities = 66/367 (17%), Positives = 150/367 (40%), Gaps = 28/367 (7%)
Query: 35 LEEEYKRLNAELQA--KTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYS---LRG 89
LE+ + +L E+ + +++ KE+ ++ + + T+ + D + +
Sbjct: 1271 LEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMER 1330
Query: 90 LLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKL-KYSDVQTADDVAI 148
L +E E K TK D + ++ L + K + L K + Q+ + ++
Sbjct: 1331 LRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSL 1390
Query: 149 PEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTE----AQIRFLKAKLHVM 204
D K +S++E ++ I+ G+S + + K L +
Sbjct: 1391 NMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRL 1450
Query: 205 QEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKY 264
QE L + E ++ ++ I+ + ++ EE+ + Q+ + + + E +
Sbjct: 1451 QEVLQS---ESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEI 1507
Query: 265 DGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIA 324
+Q+QL ++ +L+NK +Q+ + +++ E+ + K + + +
Sbjct: 1508 STIQKQLEAINDKLQNK--IQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQ 1565
Query: 325 NEEHKKIEVLKSENKKLEKQKG-ELMIGFKKQLKLI--------DVLKRQKMHIEAAKML 375
+ E K +E+ N+ E Q+ ++MI K+++K + D LK I AKM
Sbjct: 1566 SIESKMLEL---TNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEI-VAKMK 1621
Query: 376 SFTEEEF 382
E+E+
Sbjct: 1622 ESQEKEY 1628
Score = 39.3 bits (90), Expect = 0.006
Identities = 66/363 (18%), Positives = 146/363 (40%), Gaps = 57/363 (15%)
Query: 43 NAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYS------------LRGL 90
N EL+ K ++ K++ D Q +S+ + + D E + + G
Sbjct: 648 NLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGK 707
Query: 91 LPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPE 150
+P + + +L E K + +Q +L NK + N +++ ++V +
Sbjct: 708 VPKDLLCNLELEGK--------ITDLQKEL---NKEVEENEALR---------EEVILLS 747
Query: 151 DFSDFSLAKTISKIEGQLEEEGLPEYI-----DDIFSGVSNDIGTEAQIRFLKAKLHVMQ 205
+ SL + ++ +++++ +I D +FS V + E++++ L ++ +
Sbjct: 748 ELK--SLPSEVERLRKEIQDKSEELHIITSEKDKLFSEV---VHKESRVQGLLEEIGKTK 802
Query: 206 EELDNVVCECNKKEDEIQNLKSQVKNFEEDF---MRQQRTINMQQSQVEKYKTLFE---- 258
++L + E QN K+ +FE+ + + + +N + + K F+
Sbjct: 803 DDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLG 862
Query: 259 ----EANKKYDGLQQQLSSVERELENKRRLQKQAASSQSA--TEVRLNRALEEAEKYKLE 312
E + K LQ++ V+ L +L++Q + S T R + E + LE
Sbjct: 863 ALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLE 922
Query: 313 LSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAA 372
K KD + + +++ + + K + I ++QL+ + L+ K H E
Sbjct: 923 EVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLR--NALESLKQHQETI 980
Query: 373 KML 375
L
Sbjct: 981 NTL 983
Score = 37.4 bits (85), Expect = 0.023
Identities = 49/203 (24%), Positives = 90/203 (44%), Gaps = 24/203 (11%)
Query: 184 VSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTI 243
V+NDI I L+AK+H + L+ K ++ IQ L+ +V + + + +
Sbjct: 2413 VTNDI-----IAKLQAKVHESNKCLE-------KTKETIQVLQDKVALGAKPYKEEIEDL 2460
Query: 244 NMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRAL 303
M+ +++ K + A + + ++VE + E R L++ SQ A + +
Sbjct: 2461 KMKLVKIDLEK--MKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEH 2518
Query: 304 EEAEKYKLEL-----SKLRQNNKD-IANEEH----KKIEVLKSENKKLEKQKGELMIGFK 353
+ + L S + QN K I EH K+I LK +N++L KQK EL+ +
Sbjct: 2519 TDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQ 2578
Query: 354 KQLKLIDVLKRQKMHIEAAKMLS 376
+ K + + EA K ++
Sbjct: 2579 HLSNEVKTWKERTLKREAHKQVT 2601
Score = 35.4 bits (80), Expect = 0.089
Identities = 27/157 (17%), Positives = 69/157 (43%), Gaps = 4/157 (2%)
Query: 187 DIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQ 246
+I T + K +++++E ++V E + + + L N + Q+
Sbjct: 441 NIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQENI---- 496
Query: 247 QSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEA 306
+S++ + ++ Y+ L+ + +E +L+ K L + A + + + + + E
Sbjct: 497 ESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEI 556
Query: 307 EKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEK 343
K + N+D+ NE K+E+L+ + +++K
Sbjct: 557 SNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKK 593
Score = 35.4 bits (80), Expect = 0.089
Identities = 71/367 (19%), Positives = 154/367 (41%), Gaps = 55/367 (14%)
Query: 36 EEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEG 95
+++ +RL LQ+++ + + KEI+ E C E + ++ L +
Sbjct: 1444 KDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHC--CLKEQEETINELRVN-- 1499
Query: 96 IVHLHSETKPKTKNIDPVN-KVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSD 154
+ +E K ++ +N K+QNK+ + ++ ++K + S+VQ + V + F +
Sbjct: 1500 LSEKETEISTIQKQLEAINDKLQNKIQEIYE-KEEQFNIK-QISEVQ--EKVNELKQFKE 1555
Query: 155 FSLAK--TISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVV 212
AK + IE ++ E L + + + I + +++ ++ L + +++L
Sbjct: 1556 HRKAKDSALQSIESKMLE--LTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKE-- 1611
Query: 213 CECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQ-- 270
N KE + +SQ K ++ M + ++E K FE + ++ +
Sbjct: 1612 ---NTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENI 1668
Query: 271 -LSSVERE-LENKRRLQKQAASSQSATEV--------------RLNRALEEAEKYKLELS 314
L+ + E LE R + K+ +S E + R LE+ E+ K+
Sbjct: 1669 RLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHM 1728
Query: 315 KLRQNNKDI----------ANE--------EHKKIEVLKSENKKLEKQKGELMIGFKKQL 356
L+++ + I NE EH + LK+++ K++++ + K+Q
Sbjct: 1729 HLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSN-DALKAQDLKIQEELRIAHMHLKEQQ 1787
Query: 357 KLIDVLK 363
+ ID L+
Sbjct: 1788 ETIDKLR 1794
Score = 35.0 bits (79), Expect = 0.12
Identities = 78/369 (21%), Positives = 143/369 (38%), Gaps = 36/369 (9%)
Query: 44 AELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSET 103
AE++ K + QQ +E + V+ Q K + E+ L+ L ++ + H ET
Sbjct: 1123 AEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIEN---LKNELKNKELTLEHMET 1179
Query: 104 KPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISK 163
+ + + +N+ ++ S K RK ++ + + I E + K K
Sbjct: 1180 E-RLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELK 1238
Query: 164 IEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAK----------LHVMQEELDNV-- 211
I + + E ID++ VS + L+ LH QE L NV
Sbjct: 1239 I-AHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKE 1297
Query: 212 VCECNKKEDEIQNLKSQVKN---------------FEEDFMRQQRTINMQQSQVEKYKTL 256
V E + +E++ L Q E F Q I + + KT+
Sbjct: 1298 VSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTI 1357
Query: 257 FEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKL 316
E K+D L++ + +++ + Q+Q+ + + + + + E E++K + S L
Sbjct: 1358 KEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKE-KDNETTKIVSEMEQFKPKDSAL 1416
Query: 317 RQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLS 376
+ ++ K+++ E K + K+K +L + D LK I AK L
Sbjct: 1417 LRIEIEMLGLS-KRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEI-VAKHLE 1474
Query: 377 FTEEEFMKA 385
TEEE A
Sbjct: 1475 -TEEELKVA 1482
Score = 34.3 bits (77), Expect = 0.20
Identities = 44/210 (20%), Positives = 89/210 (42%), Gaps = 38/210 (18%)
Query: 197 LKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTL 256
L+ K+ ++ ++ + +K +DE+Q +++ E +R + +NM ++ +
Sbjct: 1943 LREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINE---- 1998
Query: 257 FEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKL 316
E+ K+++ Q LS ++N + +K L+ +LEE E +L
Sbjct: 1999 MEQLKKQFEA--QNLSMQSVRMDNFQLTKK------------LHESLEEIRIVAKERDEL 2044
Query: 317 RQNNKDIANEEHKKIEVLKS------ENKKLEKQKGELMIG--------FKKQLKLIDVL 362
R+ + + E + I L+ +N +++ +K L G +K ++ ++L
Sbjct: 2045 RRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELL 2104
Query: 363 KRQKM---HIEAAKMLSF---TEEEFMKAL 386
KR H E LS E EF K L
Sbjct: 2105 KRYSEMDDHYECLNRLSLDLEKEIEFQKEL 2134
Score = 33.9 bits (76), Expect = 0.26
Identities = 36/161 (22%), Positives = 71/161 (44%), Gaps = 13/161 (8%)
Query: 223 QNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVE-RELENK 281
Q+LKS + E+ F Q S + T + N QL++ + RELEN
Sbjct: 2330 QDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENS 2389
Query: 282 RRLQKQAASSQSATEVRLNRALEEAEKYKLEL-SKLRQNNKDIANEEHKKIEVLKSENKK 340
K++A + + +++ + LE +L +K+ ++NK L+ +
Sbjct: 2390 LHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNK-----------CLEKTKET 2438
Query: 341 LEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEE 381
++ + ++ +G K + I+ LK + + I+ KM + E E
Sbjct: 2439 IQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFE 2479
Score = 32.7 bits (73), Expect = 0.58
Identities = 59/322 (18%), Positives = 143/322 (44%), Gaps = 35/322 (10%)
Query: 28 PGPDLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSL 87
P LL E LN+ L+A ++V +++ +++E+ + +K +D D++
Sbjct: 486 PATKLLNQENIESELNS-LRADYDNLVLDYEQLRTEKEEMELK-----LKEKNDLDEFEA 539
Query: 88 RGLLPSEG----IVHLHSETKPKTKNIDPVNK-VQNKLHSANK--GRKTNSSVKLK-YSD 139
+ ++H S K K+ + N+ ++N+L S + K + KL+ Y D
Sbjct: 540 LERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYID 599
Query: 140 VQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKA 199
Q +++ + L+ ++ IE + + +F + + + + FL++
Sbjct: 600 SQKLENIKM-------DLSYSLESIEDPKQMK------QTLFDAETVALDAKRESAFLRS 646
Query: 200 KLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEE 259
+ ++E++ + + E++IQ +SQ++ ++ + ++ + +++ K +L +
Sbjct: 647 ENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLID- 705
Query: 260 ANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQN 319
K L L + + ++ L K+ +++ E + L E + E+ +LR+
Sbjct: 706 -GKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVI--LLSELKSLPSEVERLRKE 762
Query: 320 NKDIANEEHKKIEVLKSENKKL 341
+D + E H ++ SE KL
Sbjct: 763 IQDKSEELH----IITSEKDKL 780
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 56.2 bits (134), Expect = 5e-08
Identities = 34/155 (21%), Positives = 80/155 (51%), Gaps = 3/155 (1%)
Query: 207 ELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDG 266
E +NV + +KED I+ S+V++ +++ R+ + Q+Q ++ + L +E +++
Sbjct: 34 EKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQ 93
Query: 267 LQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANE 326
L++QL V ++ + +L + ++ E +++ EE K + ELS+L+Q ++
Sbjct: 94 LEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEES 153
Query: 327 EHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDV 361
L+ + L+ + E+ Q+KL+++
Sbjct: 154 VESGKAQLEPLQQHLQDSQQEIS---SMQMKLMEM 185
Score = 34.3 bits (77), Expect = 0.20
Identities = 34/159 (21%), Positives = 77/159 (48%), Gaps = 15/159 (9%)
Query: 170 EEGLPEYIDDIFSGVSN--DIGTEAQ-----IRFLKAKLHVMQEELDNVVCECNKKEDEI 222
E+ L E D I S D+ E Q ++ L+A+ +QE LD + + + E+++
Sbjct: 39 EQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQL 98
Query: 223 QNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKR 282
+ ++ + + + + Q+SQ+ Y+ +A ++ LQQ+ + +E +E+ +
Sbjct: 99 KEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREELSRLQQETAELEESVESGK 158
Query: 283 R----LQKQAASSQ---SATEVRLNRALEEAEKYKLELS 314
LQ+ SQ S+ +++L +++ E + +L+
Sbjct: 159 AQLEPLQQHLQDSQQEISSMQMKL-MEMKDLENHNSQLN 196
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 54.3 bits (129), Expect = 2e-07
Identities = 69/346 (19%), Positives = 137/346 (39%), Gaps = 38/346 (10%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGL 90
DLL E + + + + + Q + + R+ QE R+R + KS D+D Y L+ +
Sbjct: 552 DLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQE-RNR-ILENSKSQTDKDYYQLQAI 609
Query: 91 LPSEG----------------IVHLHSETKPKTKNIDPVN----KVQNKLHSANKGRKTN 130
L +E I L E K N++ V + Q+ L+ + K K N
Sbjct: 610 LEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEK-EKNN 668
Query: 131 SSVKLKYS------------DVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYID 178
+ L Y + + + AK+++ E E+ L E +
Sbjct: 669 LEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCE---MEKKLKEERE 725
Query: 179 DIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMR 238
+ + E Q L L Q++L+++ + EDE++NL Q++ +
Sbjct: 726 AREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLL 785
Query: 239 QQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVR 298
Q + Q + + K L ++ ++ + L + +E EL + + + +
Sbjct: 786 LQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQ 845
Query: 299 LNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQ 344
L + YK ++ +L++ ++ E KKI+ L++E + L Q
Sbjct: 846 LEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQ 891
Score = 51.6 bits (122), Expect = 1e-06
Identities = 50/191 (26%), Positives = 92/191 (48%), Gaps = 31/191 (16%)
Query: 156 SLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCEC 215
SL KTI K+E QL E + D+ ++ K +LD ++ E
Sbjct: 427 SLQKTIYKLEEQLHNE--MQLKDE-----------------MEQKCRTSNIKLDKIMKEL 467
Query: 216 NKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVE 275
+++ ++ +NL+S V E++ M Q IN +Y+ E+ N+K ++ ++S+++
Sbjct: 468 DEEGNQRRNLESTVSQIEKEKMLLQHRIN-------EYQRKAEQENEKRRNVENEVSTLK 520
Query: 276 RELENKRRLQKQAASSQSATE--VRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEV 333
+LE+ L+K + +SQ A E +L + LEEA S + E K I
Sbjct: 521 DQLED---LKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQ 577
Query: 334 LKSENKKLEKQ 344
L+S N++L+++
Sbjct: 578 LESLNRELQER 588
Score = 42.0 bits (97), Expect = 0.001
Identities = 53/278 (19%), Positives = 122/278 (43%), Gaps = 36/278 (12%)
Query: 113 VNKVQNKLHSAN-KGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEE 171
+N+ Q K N K R + V ++ V+ ++ + +S+++ QLEE
Sbjct: 495 INEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLAN----EKLSQLQKQLEEA 550
Query: 172 GLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKN 231
+D+ S+ T ++R ++ +L+++ E ++ ++N KSQ
Sbjct: 551 ------NDLLRTESD---TAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQT-- 599
Query: 232 FEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAAS- 290
++D+ + Q + ++ + + + LQ+++ ++ LE +K+A
Sbjct: 600 -DKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDM 658
Query: 291 ------SQSATEVRLNRALE------EAEKYKLELSKLRQNNKDIANEEHKKIEVLKSEN 338
++ E+ LN L+ E E + +++K R +K + EE K + + + E
Sbjct: 659 LNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEK 718
Query: 339 KKLEKQKGE-----LMIGFKKQLKLIDV-LKRQKMHIE 370
K E+++ ++ +KQ ++DV LK+ + +E
Sbjct: 719 KLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLE 756
>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
Length = 388
Score = 54.3 bits (129), Expect = 2e-07
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 11/152 (7%)
Query: 169 EEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQ 228
E+E L I D+ +G + D+ E + LK KLH E N KE EI+NLK+
Sbjct: 145 EQEELQMKISDLITGATRDLRQE--VTTLKEKLHKSHTRYTE---ESNSKEKEIENLKNL 199
Query: 229 VKNFEEDFMRQQRTINMQQSQVEKYKTLFEEAN---KKYDGLQQQLSSVERELENKRRLQ 285
V FE R ++ I+ S E + E+ + K+ Q QL + + +
Sbjct: 200 VAEFES---RLKKEIDSNDSVSENLRKEMEQKSDELKRVMLAQTQLIEQFNQSQEENTFL 256
Query: 286 KQAASSQSATEVRLNRALEEAEKYKLELSKLR 317
++ + L AL +A + LELSKLR
Sbjct: 257 QETVRRECEERFELTEALSQAREQLLELSKLR 288
Score = 33.1 bits (74), Expect = 0.44
Identities = 30/118 (25%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 264 YDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELS-KLRQNNKD 322
Y LQ++L+ E++ E+ +R A + T+ LN+ EE K E L + K
Sbjct: 17 YKALQEELTVKEKQEEDIKRRINLAENELEITKTLLNQTREEVLTLKNERELMLISHQKS 76
Query: 323 IAN-EEHKKIEVLKSENKK------LEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAK 373
I +E + ++L +N K L K++ + ++ F++Q L + ++ IE K
Sbjct: 77 IEQLQETLRQKLLSDDNWKEKIEAELAKERAQHLVEFEEQALLFKEETKLQLDIEKEK 134
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 53.9 bits (128), Expect = 2e-07
Identities = 88/399 (22%), Positives = 176/399 (44%), Gaps = 71/399 (17%)
Query: 36 EEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRP---VSTQ------------MKSCD 80
EEE +RL +L K ++ QQ++ I + +Q++ + VST+ ++S +
Sbjct: 418 EEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSEN 477
Query: 81 DEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDV 140
D ++ +L + + L K++ ++ ++ QN+L +K + + L+ S++
Sbjct: 478 DAAKDEVKEVL--QALEELAVNYDQKSQEVEEKSQ-QNQLLVDELSQKVATMLSLE-SEL 533
Query: 141 QTADDVA-------------IPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSND 187
Q +V+ + +D S+FS+ +I+ +E SG +
Sbjct: 534 QRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVE-----------ISGAIEE 582
Query: 188 IGTEAQIRFLKAKLHVMQ-----EELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRT 242
T A++ K K V +L+N+ EC++K + S + + R+
Sbjct: 583 EFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRS 642
Query: 243 INMQQSQVEKYKTLFEEANKKYDGLQQQLSSVE-RELENKRRLQKQAASSQSATEVRLNR 301
+ VE K EE+ YD L +L+ ++ +E ++ L+ + +Q A EV+ +
Sbjct: 643 LTEYMQSVELKKRHLEES---YDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVK--K 697
Query: 302 ALE-----EAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGF---- 352
ALE E + +L++LR D NE+ K I+ LK N+KL+ + +L +
Sbjct: 698 ALELQMESHREAHHRQLARLR----DEINEKQKTIDELKDLNQKLQLELEKLQADYEKLK 753
Query: 353 ----KKQLKLIDVLKRQKMHIEAAKMLSFTEEEFMKALE 387
+K KL ++ + H ++ + L EE + L+
Sbjct: 754 SEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQ 792
Score = 35.0 bits (79), Expect = 0.12
Identities = 68/354 (19%), Positives = 144/354 (40%), Gaps = 56/354 (15%)
Query: 32 LLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMK-----SCDDEDDYS 86
+L+LE E +RL + + + +++D E + ++K S E++++
Sbjct: 526 MLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFT 585
Query: 87 LRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANK--GRKTNS------------- 131
+ L S+ + SE K K + +Q + H + GR+ +S
Sbjct: 586 VARLYISK----IKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIR 641
Query: 132 -------SVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQ--LEEEGLPEYIDDIFS 182
SV+LK ++ + D SL+ ++K++ Q + E L + D
Sbjct: 642 SLTEYMQSVELKKRHLEESYD----------SLSDELAKLQAQETVHEVALKDKEPDTQD 691
Query: 183 GVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEI----QNLKSQVKNFEEDFMR 238
E Q+ + H L + + E K DE+ Q L+ +++ + D+ +
Sbjct: 692 ADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEK 751
Query: 239 QQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVR 298
+ + + +++++ L+E + L+ +V REL+ L+K + T V+
Sbjct: 752 LKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVT-TRVK 810
Query: 299 LNRALEEAEKYKLELSKLR----QNNKDIANEEHKKI----EVLKSENKKLEKQ 344
+ +E + + K + +NN + + HK++ L+ E KLEK+
Sbjct: 811 KSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKR 864
Score = 33.9 bits (76), Expect = 0.26
Identities = 39/205 (19%), Positives = 79/205 (38%), Gaps = 22/205 (10%)
Query: 159 KTISKIEGQLEE----EGLPEYIDDIFSGVSNDIGTEA------------QIRFLKAKLH 202
+TI+K+E +L E +PE + +G +G E +R +
Sbjct: 358 ETIAKLEAELSRWRNGENVPE--TERLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQ 415
Query: 203 VMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANK 262
+EE+ + + + K+DEI ++ ++ + Q+ + + EK +
Sbjct: 416 KYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQS 475
Query: 263 KYDGLQQQLSSVERELEN---KRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQN 319
+ D + ++ V + LE + Q +S L L + L L Q
Sbjct: 476 ENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQR 535
Query: 320 NKDIANEEHKKI-EVLKSENKKLEK 343
++++ + K+I EVL K L +
Sbjct: 536 LQEVSGHQRKRIAEVLNGLMKDLSE 560
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 53.5 bits (127), Expect = 3e-07
Identities = 75/358 (20%), Positives = 147/358 (41%), Gaps = 52/358 (14%)
Query: 38 EYKRLNAELQAKTADVVQQAK---EIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSE 94
E + L ++L A+ + +Q + E+ + +E+R+R + + + + D R E
Sbjct: 870 EMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEE 929
Query: 95 GIVHLHSETKPKTKNIDPVNKVQNKLHSANKG---RKTNSSVKLKYSDVQTADDVAIPED 151
HL +E K +NI + + + SA + K + KLK + ++ I ED
Sbjct: 930 RCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK----KLEEEQIILED 985
Query: 152 FSDFSLAKTISKIEGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELD 209
+ LAK +E ++ E L E + S EA I L+ +L +++
Sbjct: 986 -QNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 210 NVVCECNKKE-------DEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANK 262
+ K E D+I L++Q+ + +++ + ++VE+ A K
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 263 KYDGLQQQLSSVERELENKRRLQKQAA----------------------SSQSATEVRLN 300
K L+ Q+S ++ +LE++R + +A S+ + E+R
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 301 RAL----------EEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGEL 348
R EEA+ ++ ++ ++RQ + E +++E K LEK K L
Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Score = 48.9 bits (115), Expect = 8e-06
Identities = 82/397 (20%), Positives = 160/397 (40%), Gaps = 55/397 (13%)
Query: 23 QQPSTPGPDLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDE 82
Q+ S +L E+ KR+ A L+ +AK+ + + + + V ++ D
Sbjct: 1192 QKHSQAVEELAEQLEQTKRVKANLE--------KAKQTLENERGELANEVKVLLQGKGDS 1243
Query: 83 DDYSLRGLLPSEGI-VHLHSETKPKTKNIDPVNKVQNKL--------HSANKGRKTNSSV 133
+ + + + V + + +T+ D V K+Q +L S +K K
Sbjct: 1244 EHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDF 1303
Query: 134 KLKYSDVQTADDVAIPEDFSDFSLAKTISKIEG-------QLEEEG------------LP 174
S +Q ++ E+ SL+ + ++E QLEEE L
Sbjct: 1304 SALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLH 1363
Query: 175 EYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEE 234
+ D+ + + +G +K KL E L E D+++ K++++ +
Sbjct: 1364 AQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELD 1423
Query: 235 DFM-----RQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAA 289
D + ++Q N+++ Q KK+D L + ++ + +R + A
Sbjct: 1424 DLLVDLDHQRQSACNLEKKQ------------KKFDQLLAEEKTISAKYAEERDRAEAEA 1471
Query: 290 SSQSATEVRLNRALEEAEKYKLELSKL-RQNNKDIANEEHKKIEVLKSENKKLEKQKGEL 348
+ + L RALEEA + K EL +L +Q ++ + K +V KS + +LEK K L
Sbjct: 1472 REKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH-ELEKSKRAL 1530
Query: 349 MIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFMKA 385
++ ++ L+ + E AK+ + MKA
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKA 1567
Score = 46.2 bits (108), Expect = 5e-05
Identities = 72/326 (22%), Positives = 131/326 (40%), Gaps = 55/326 (16%)
Query: 40 KRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHL 99
K+L +L+ A + K RD + R + QMK C E D + E I+
Sbjct: 1613 KKLEMDLKDLEAHIDSANKN--RDEAIKQLRKLQAQMKDCMRELDDTRAS---REEILAQ 1667
Query: 100 HSETKPKTKNIDP-VNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLA 158
E + K K+++ + ++Q +L +A + ++ + + + AD++A +L
Sbjct: 1668 AKENEKKLKSMEAEMIQLQEELAAAERAKR-----QAQQERDELADEIANSSGKGALALE 1722
Query: 159 KT------ISKIEGQLEEE-GLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQ--EELD 209
+ I+++E +LEEE G E I+D R KA L + Q +L+
Sbjct: 1723 EKRRLEARIAQLEEELEEEQGNTELIND---------------RLKKANLQIDQINTDLN 1767
Query: 210 NVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQ 269
K E+ Q L+ Q K + + T+ KYK L+
Sbjct: 1768 LERSHAQKNENARQQLERQNKELKVKLQEMEGTVK------SKYKA-------SITALEA 1814
Query: 270 QLSSVERELENKRRLQKQAASSQSATEVRLNRAL-------EEAEKYKLELSKLRQNNKD 322
+++ +E +L+N+ + ++ A TE +L L AE+YK + K K
Sbjct: 1815 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 1874
Query: 323 IANEEHKKIEVLKSENKKLEKQKGEL 348
+ + + E + N K + EL
Sbjct: 1875 LKRQLEEAEEEAQRANASRRKLQREL 1900
Score = 42.4 bits (98), Expect = 7e-04
Identities = 59/295 (20%), Positives = 129/295 (43%), Gaps = 47/295 (15%)
Query: 31 DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGL 90
++LA +E ++ +L++ A+++Q +E+ + + + + + D+ + S +G
Sbjct: 1663 EILAQAKENEK---KLKSMEAEMIQLQEELAA-AERAKRQAQQERDELADEIANSSGKGA 1718
Query: 91 LPSEG-------IVHLHSETKPKTKNIDPVNKVQNKLHSAN-KGRKTNSSVKLKYSDVQT 142
L E I L E + + N + +N ++L AN + + N+ + L+ S Q
Sbjct: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELIN---DRLKKANLQIDQINTDLNLERSHAQK 1775
Query: 143 ADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLH 202
++ + + L + ++EG ++ + +A I L+AK+
Sbjct: 1776 NENARQQLERQNKELKVKLQEMEGTVKSK------------------YKASITALEAKIA 1817
Query: 203 VMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANK 262
++E+LDN + E Q QV+ E+ ++ ++ E+YK ++A+
Sbjct: 1818 QLEEQLDN-------ETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKAST 1870
Query: 263 KYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLR 317
+ L++QL E E + +A +S+ + L A E A+ E+S L+
Sbjct: 1871 RLKQLKRQLEEAEEEAQ-------RANASRRKLQRELEDATETADAMNREVSSLK 1918
Score = 42.0 bits (97), Expect = 0.001
Identities = 57/315 (18%), Positives = 127/315 (40%), Gaps = 30/315 (9%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSE 94
LEEE K A++Q Q +E+ ++ + + + E++ RG L +E
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENE---RGELANE 1232
Query: 95 GIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSD 154
V L + + K ++Q N+G + +
Sbjct: 1233 VKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE---------------------- 1270
Query: 155 FSLAKTISKIEGQLEE-EGLPEYIDDIFSGVSNDIGT-EAQIRFLKAKLHVMQEELDNVV 212
LA ++K++ +L+ GL D S ++ D E+Q++ + L + ++
Sbjct: 1271 --LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLS 1328
Query: 213 CECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLS 272
+ + EDE + + Q++ EE ++ I +QV K E++ + ++
Sbjct: 1329 TKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKR 1388
Query: 273 SVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIE 332
++++LE + ++ ++ E R +E + ++L RQ+ ++ ++ KK +
Sbjct: 1389 KLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL-EKKQKKFD 1447
Query: 333 VLKSENKKLEKQKGE 347
L +E K + + E
Sbjct: 1448 QLLAEEKTISAKYAE 1462
Score = 38.1 bits (87), Expect = 0.014
Identities = 53/265 (20%), Positives = 111/265 (41%), Gaps = 27/265 (10%)
Query: 106 KTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTA-DDVAIPEDFSDFSLAKTISKI 164
+TK + ++ + + + N + + D+ ++ DDV S L K+ +
Sbjct: 1475 ETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK----SVHELEKSKRAL 1530
Query: 165 EGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLH--------VMQEELDNVVCE 214
E Q+EE L E D++ + + E ++ +KA+ +E+ +V +
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 215 CNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSV 274
+ E E+++ + Q + + + ++ ++ +EA K+ LQ Q+
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDC 1650
Query: 275 ERELENKRRLQKQAAS----------SQSATEVRLNRALEEAEKYKLELSKLRQNNKD-I 323
REL++ R +++ + S A ++L L AE+ K + + R D I
Sbjct: 1651 MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710
Query: 324 ANEEHKKIEVLKSENKKLEKQKGEL 348
AN K L+ E ++LE + +L
Sbjct: 1711 ANSSGKGALALE-EKRRLEARIAQL 1734
Score = 34.7 bits (78), Expect = 0.15
Identities = 31/160 (19%), Positives = 70/160 (43%), Gaps = 11/160 (6%)
Query: 193 QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEK 252
Q+ + ++ +EEL V +K+ +N ++++ + M ++ + Q +
Sbjct: 839 QVSRQEEEMMAKEEELVKV----REKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETE 894
Query: 253 YKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLE 312
EE + +Q+L + +LE + +++ A + ++ + ++E E+ E
Sbjct: 895 LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEE 954
Query: 313 LSKLRQN---NKDIANEEHKKIE----VLKSENKKLEKQK 345
RQ K + KK+E +L+ +N KL K+K
Sbjct: 955 EESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEK 994
Score = 34.3 bits (77), Expect = 0.20
Identities = 87/428 (20%), Positives = 168/428 (39%), Gaps = 85/428 (19%)
Query: 36 EEEYKRLNAE---LQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSL----- 87
EE + L AE +Q ++ +Q +E RQ+++ V+T+ K E++ +
Sbjct: 928 EERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN 987
Query: 88 ------RGLLP---SEGIVHLHSE-------TKPKTKNIDPVNKVQNKLHSANKGRKTNS 131
+ LL +E +L E K K K+ + ++ +L K R+
Sbjct: 988 CKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELE 1047
Query: 132 SV--KLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQL--EEEGLPEYIDDIFSGVSND 187
KL+ +D +A L I++++ QL +EE L + + +
Sbjct: 1048 KTRRKLEGDSTDLSDQIA--------ELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099
Query: 188 IGTEAQIRFLKAKLHVMQEELDNVVCECNKKE-------DEIQNLKSQVKNFEEDFMRQQ 240
+IR L++++ +QE+L++ NK E +E++ LK+++++ + QQ
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 241 RTINMQQSQVEKYKTLFEEANKKYDG---------------LQQQLSSVER--------- 276
+ ++ +V K EE K ++ L +QL +R
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
Query: 277 -ELENKR---------RLQKQAASSQSATEV-----RLNRALEEAEKYKLELS-KLRQNN 320
LEN+R LQ + S +V L E E+ + EL+ K+ +
Sbjct: 1220 QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279
Query: 321 KDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEA-AKMLSFTE 379
++ N + S++ KL K L + +L+ RQK+ + K + +
Sbjct: 1280 VELDNVT-GLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEK 1338
Query: 380 EEFMKALE 387
F + LE
Sbjct: 1339 NSFREQLE 1346
Score = 29.3 bits (64), Expect = 6.4
Identities = 32/142 (22%), Positives = 66/142 (46%), Gaps = 29/142 (20%)
Query: 268 QQQLSSVERELENKRRLQKQAASSQSATE------------VRLNRALE-------EAEK 308
++++ + E EL R +KQ A+ TE ++L L+ EAE+
Sbjct: 844 EEEMMAKEEELVKVR--EKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEE 901
Query: 309 YKLELSKLRQNNKDIAN-------EEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDV 361
+ L+ +Q ++I + EE ++ + L++E KK+++ EL +++
Sbjct: 902 LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQK 961
Query: 362 LKRQKMHIEAAKMLSFTEEEFM 383
L+ +K+ E AK+ EE+ +
Sbjct: 962 LQLEKVTTE-AKLKKLEEEQII 982
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 53.5 bits (127), Expect = 3e-07
Identities = 72/345 (20%), Positives = 147/345 (42%), Gaps = 44/345 (12%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSE 94
L+ E K++ A +Q D+ +Q E RQ+++ V+ + K E++ L S+
Sbjct: 941 LQNEKKKMQAHIQ----DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSK 996
Query: 95 GIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSD-VQTADDVAIPEDFS 153
I K K D + + ++L + K + ++ K + ++ E+ +
Sbjct: 997 FI-------KEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKT 1049
Query: 154 DFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEEL----- 208
L K K++G+ + L + I ++ +AQI LK +L +EEL
Sbjct: 1050 RQELEKAKRKLDGETTD--LQDQIAEL----------QAQIDELKLQLAKKEEELQGALA 1097
Query: 209 --DNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDG 266
D+ N ++ L++Q+ +EDF ++ + N + Q + L EE
Sbjct: 1098 RGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ---KRDLSEELEALKTE 1154
Query: 267 LQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANE 326
L+ L + + E + + +++ A + A E EE + ++ ++ +RQ + E
Sbjct: 1155 LEDTLDTTAAQQELRTKREQEVAELKKALE-------EETKNHEAQIQDMRQRHATALEE 1207
Query: 327 EHKKIEVLKSENKKLEKQKGELMIGFKK---QLKLIDVLKRQKMH 368
+++E K LEK K L K+ ++K++ +K + H
Sbjct: 1208 LSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEH 1252
Score = 48.9 bits (115), Expect = 8e-06
Identities = 78/394 (19%), Positives = 164/394 (41%), Gaps = 66/394 (16%)
Query: 34 ALEEEYKRLNAELQ----------AKTADVVQQAKE----IIRDRQ--EVRSRPVSTQMK 77
ALEEE K A++Q + ++ ++QAK + +++Q E ++ ++ ++K
Sbjct: 1182 ALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVK 1241
Query: 78 SCDD---EDDYSLRGLLPSEGIVHLHSETKP----KTKNIDPVNKVQNKLHSAN------ 124
E ++ + L + LH++ + + + +K+QN+L + +
Sbjct: 1242 VLQQVKAESEHKRKKL--DAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEA 1299
Query: 125 --KGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEG-------QLEEE---- 171
KG K S +Q ++ E +L+ I ++E Q EEE
Sbjct: 1300 EKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEAR 1359
Query: 172 --------GLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQ 223
L + D V +D+GT + K KL E L + E D+++
Sbjct: 1360 KNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLE 1419
Query: 224 NLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRR 283
K++++ +D T+++ + + + E+ KK+D L + S+ +R
Sbjct: 1420 KTKNRLQQELDDL-----TVDLDHQR--QVASNLEKKQKKFDQLLAEEKSISARYAEERD 1472
Query: 284 LQKQAASSQSATEVRLNRALEEA----EKYKLELSKLRQNNKDIANEEH---KKIEVLKS 336
+ A + + L RALEEA E+++ + +LR + +D+ + + K + L+
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532
Query: 337 ENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIE 370
+ LE+Q E+ ++ + + K+ +E
Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLE 1566
Score = 45.8 bits (107), Expect = 7e-05
Identities = 61/330 (18%), Positives = 142/330 (43%), Gaps = 46/330 (13%)
Query: 45 ELQAKTADVVQ--QAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSE 102
ELQA+ A++ + ++++ R++ E + R +S ++++ E + +L + +
Sbjct: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQEL------ 1168
Query: 103 TKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTIS 162
+TK V +++ L K + + D++ A+ E AK
Sbjct: 1169 ---RTKREQEVAELKKALEEETKNHEA------QIQDMRQRHATALEELSEQLEQAK--- 1216
Query: 163 KIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEI 222
+ + LE+ N G E + L ++ V+Q+ + K + ++
Sbjct: 1217 RFKANLEK---------------NKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQV 1261
Query: 223 QNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKR 282
Q L ++V + + + Q++++ TL EEA KK + +S+E +L++ +
Sbjct: 1262 QELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQ 1321
Query: 283 RLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSE----N 338
L ++ ++ ++ L+ + + E+ K L + ++ ++ K++ L+S+
Sbjct: 1322 ELLQE----ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Query: 339 KKLEKQKG---ELMIGFKKQLKLIDVLKRQ 365
KK++ G L KK LK + L ++
Sbjct: 1378 KKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407
Score = 43.9 bits (102), Expect = 3e-04
Identities = 75/349 (21%), Positives = 149/349 (42%), Gaps = 37/349 (10%)
Query: 45 ELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETK 104
E+ K + +A RD + R + QMK E + + + I E++
Sbjct: 1623 EIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARAS---RDEIFAQSKESE 1679
Query: 105 PKTKNIDP-VNKVQNKLHSANKGRKTNSSVKLKYSDVQT---ADDVAIPEDFSDFSLAKT 160
K K+++ + ++Q +L S+ + R+ + + +D T + A+ ++ L
Sbjct: 1680 KKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKR--RLEAR 1737
Query: 161 ISKIEGQLEEE-GLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQ---EELDNVVCECN 216
I+++E +LEEE E ++D F T Q+ L A+L + ++ DN +
Sbjct: 1738 IAQLEEELEEEQSNMELLNDRFRK------TTLQVDTLNAELAAERSAAQKSDNARQQLE 1791
Query: 217 KKEDEI----QNLKSQVKN-FEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQL 271
++ E+ Q L+ VK+ F+ + I + Q+E+ ANK +++L
Sbjct: 1792 RQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKL 1851
Query: 272 SSVERELENKRR---LQKQAASSQSATEVRLNRALEEAEKYKLELSKLR---QNNKDIAN 325
+ ++E++RR K+ +A +L R LEEAE+ + R Q D A
Sbjct: 1852 KEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDAT 1911
Query: 326 EEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKM 374
E ++ + S K ++ G + + R+++H+E A +
Sbjct: 1912 EANEGLSREVSTLKNRLRRGGPISFSSSRS-------GRRQLHLEGASL 1953
Score = 41.6 bits (96), Expect = 0.001
Identities = 50/243 (20%), Positives = 116/243 (47%), Gaps = 25/243 (10%)
Query: 162 SKIEGQLEE-----EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVV--CE 214
+K+EG+LEE + L E + + + + A+ ++A+L ++EL+ ++ E
Sbjct: 869 TKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLE 928
Query: 215 CNKKEDEIQN--LKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLS 272
+E+E +N L+++ K + + ++ ++ +K + A K +++++
Sbjct: 929 SRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEIL 988
Query: 273 SVERE----LENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEH 328
+E + ++ K+ ++ + A S + EE EK K L+K+R + + ++
Sbjct: 989 LLEDQNSKFIKEKKLMEDRIAECSS-------QLAEEEEKAK-NLAKIRNKQEVMISDLE 1040
Query: 329 KKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKM-LSFTEEEFMKALE 387
++++ + ++LEK K +L + L D + + I+ K+ L+ EEE AL
Sbjct: 1041 ERLKKEEKTRQELEKAKRKL---DGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALA 1097
Query: 388 WGN 390
G+
Sbjct: 1098 RGD 1100
Score = 37.7 bits (86), Expect = 0.018
Identities = 66/343 (19%), Positives = 130/343 (37%), Gaps = 48/343 (13%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDD--EDDYSLRGLLP 92
LE+ RL EL T D+ D Q + + + K D ++ S+
Sbjct: 1418 LEKTKNRLQQELDDLTVDL---------DHQRQVASNLEKKQKKFDQLLAEEKSISARYA 1468
Query: 93 SEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTA-DDVAIPED 151
E + +TK + ++ L + + + N ++ D+ ++ DDV
Sbjct: 1469 EERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK--- 1525
Query: 152 FSDFSLAKTISKIEGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELD 209
+ L K+ +E Q+EE L E D++ + + E ++ +KA+ + D
Sbjct: 1526 -NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRD 1584
Query: 210 NVVCECNKKEDEIQNLKSQVKNFEEDFM--RQQRTINMQ------------QSQVEKYKT 255
+ E++ + L QV+ E + R+QR + + ++Q+E
Sbjct: 1585 E------QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANK 1638
Query: 256 LFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATE----------VRLNRALEE 305
+E K+ LQ Q+ +RELE R + + + +E ++L L
Sbjct: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELAS 1698
Query: 306 AEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGEL 348
+E+ + + R D L E ++LE + +L
Sbjct: 1699 SERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQL 1741
Score = 34.3 bits (77), Expect = 0.20
Identities = 44/166 (26%), Positives = 74/166 (44%), Gaps = 23/166 (13%)
Query: 193 QIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEK 252
Q+ + +L EEL V + K E E++ ++ + + E+ N+ Q++
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEK-------NILAEQLQA 898
Query: 253 YKTLFEEANK-------KYDGLQQQL----SSVERELENKRRLQKQAASSQSATEVRLNR 301
LF EA + K L++ L S VE E E + LQ + Q+ + L
Sbjct: 899 ETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQ-DLEE 957
Query: 302 ALEEAE--KYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQK 345
L+E E + KL+L K+ K EE +I +L+ +N K K+K
Sbjct: 958 QLDEEEGARQKLQLEKVTAEAKIKKMEE--EILLLEDQNSKFIKEK 1001
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 53.1 bits (126), Expect = 4e-07
Identities = 51/215 (23%), Positives = 97/215 (45%), Gaps = 25/215 (11%)
Query: 156 SLAKTISKIEGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNV-- 211
++ K + E +L++ E L + + + EA++ L ++ +++EELD
Sbjct: 46 AMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQE 105
Query: 212 --------VCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKK 263
+ E K DE + +K E ++ + + +Q+ Q+++ K + EEA++K
Sbjct: 106 RLATALQKLEEAEKAADESER---GMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRK 162
Query: 264 YDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLN------RALE-EAEKYKLELSKL 316
Y+ + ++L +E +LE + A S S E L ++LE +AEKY + K
Sbjct: 163 YEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKY 222
Query: 317 RQNNK---DIANEEHKKIEVLKSENKKLEKQKGEL 348
+ K D E + E + KLEK +L
Sbjct: 223 EEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDL 257
Score = 44.3 bits (103), Expect = 2e-04
Identities = 33/142 (23%), Positives = 71/142 (50%), Gaps = 4/142 (2%)
Query: 191 EAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQV 250
EA+ + + + +++EL + + EDE+ +K+ +E ++ +++V
Sbjct: 27 EAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEV 86
Query: 251 EKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYK 310
+ ++ D Q++L++ ++LE +K A S+ +V NRAL++ EK +
Sbjct: 87 ASLNRRIQLVEEELDRAQERLATALQKLE---EAEKAADESERGMKVIENRALKDEEKME 143
Query: 311 LELSKLRQNNKDIANEEHKKIE 332
L+ +L++ K IA E +K E
Sbjct: 144 LQEIQLKE-AKHIAEEADRKYE 164
Score = 39.3 bits (90), Expect = 0.006
Identities = 53/271 (19%), Positives = 111/271 (40%), Gaps = 44/271 (16%)
Query: 36 EEEYKRLNAELQAK------TADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSL-- 87
EE K+L EL A T D + + E ++D QE + + K+ D E + +
Sbjct: 34 EERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQE---KLELAEKKAADAEAEVASLN 90
Query: 88 -RGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSA-----NKGRKTNSSVKLKYSDVQ 141
R L E + + ++ K ++ N+ K ++L+ ++
Sbjct: 91 RRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLK 150
Query: 142 TADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKL 201
A +A D +A+ + IEG LE TE + ++K
Sbjct: 151 EAKHIAEEADRKYEEVARKLVIIEGDLER-------------------TEERAELAESKC 191
Query: 202 HVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEAN 261
++EEL NV + +++L++Q + + + + + I + ++++ +T E A
Sbjct: 192 SELEEELKNVT-------NNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAE 244
Query: 262 KKYDGLQQQLSSVERELENKRRLQKQAASSQ 292
+ L++ + +E EL ++L+ +A S +
Sbjct: 245 RSVAKLEKTIDDLEDEL-YAQKLKYKAISEE 274
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 53.1 bits (126), Expect = 4e-07
Identities = 46/215 (21%), Positives = 98/215 (45%), Gaps = 33/215 (15%)
Query: 197 LKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTL 256
+K K+ +++ + +N + + E + + + + K EE+ Q+ + + +VEKY
Sbjct: 4 IKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES 63
Query: 257 FEEANKKYD--------------GLQQQLSSVERELENKR-----------RLQKQAASS 291
+EA +K + L +++ VE EL+ + +K A S
Sbjct: 64 VKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 123
Query: 292 QSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSE----NKKLEKQKGE 347
+ +V NRA+++ EK +L+ +L++ K IA + +K E + + +LE+ +
Sbjct: 124 ERGMKVIENRAMKDEEKMELQEMQLKE-AKHIAEDSDRKYEEVARKLVILEGELERSEER 182
Query: 348 LMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEF 382
+ + +L + L+ +A K L +EEE+
Sbjct: 183 AEVAESRARQLEEELRTMD---QALKSLMASEEEY 214
Score = 52.8 bits (125), Expect = 5e-07
Identities = 52/248 (20%), Positives = 110/248 (44%), Gaps = 22/248 (8%)
Query: 138 SDVQTADDVAIPEDFSDFSLAKTISKIEGQLEE--EGLPEYIDDIFSGVSNDIGTEAQIR 195
+D + A+D + +L K + E ++E+ E + E + + EA +
Sbjct: 27 ADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVA 86
Query: 196 FLKAKLHVMQEELDNV----------VCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINM 245
L ++ +++EELD + E K DE + +K E M+ + + +
Sbjct: 87 SLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER---GMKVIENRAMKDEEKMEL 143
Query: 246 QQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEE 305
Q+ Q+++ K + E++++KY+ + ++L +E ELE + A S E L R +++
Sbjct: 144 QEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEEL-RTMDQ 202
Query: 306 AEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQ 365
A L L + ++ + +E K E +K +KL++ + + KL +
Sbjct: 203 A------LKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL 256
Query: 366 KMHIEAAK 373
+ + +AK
Sbjct: 257 EETLASAK 264
Score = 30.4 bits (67), Expect = 2.9
Identities = 48/279 (17%), Positives = 98/279 (35%), Gaps = 59/279 (21%)
Query: 35 LEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSL---RGLL 91
LEEE + L +L+ T D V++ E +++ QE + + K+ D E D + R L
Sbjct: 39 LEEEQQALQKKLKG-TEDEVEKYSESVKEAQEKLEQ---AEKKATDAEADVASLNRRIQL 94
Query: 92 PSEGIVHLHSETKPKTKNIDPVNKVQNKLHSA-----NKGRKTNSSVKLKYSDVQTADDV 146
E + + ++ K ++ N+ K ++L+ ++ A +
Sbjct: 95 VEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHI 154
Query: 147 AIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQE 206
A D +A+ + +EG+LE
Sbjct: 155 AEDSDRKYEEVARKLVILEGELE------------------------------------- 177
Query: 207 ELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDG 266
+ E+ + +S+ + EE+ + + + E+Y T ++ ++
Sbjct: 178 ----------RSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKL 227
Query: 267 LQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEE 305
L+++L E E R + + E L A EE
Sbjct: 228 LEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 266
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 53.1 bits (126), Expect = 4e-07
Identities = 74/304 (24%), Positives = 131/304 (43%), Gaps = 48/304 (15%)
Query: 101 SETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDV--QTADDVAIPE-DFSDFSL 157
S K + ID K KL K +K + + K +D + ++ + E + ++ +
Sbjct: 529 SSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEV 588
Query: 158 AKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNK 217
++ + + EEE E DDI G S+D KA Q +L N+ CE
Sbjct: 589 EESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDE--KANY---QADLANITCEIAI 643
Query: 218 KE---DEIQN----LKSQVKNFEEDFMRQQRTIN---MQQSQV------------EKYKT 255
K+ DE++N L++ K +EE M Q I +++ QV EK K
Sbjct: 644 KQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKK 703
Query: 256 LFEEANKKYDGLQQQLSSVE-------RELENKRRLQKQAASSQ------SATEVRLNRA 302
+ E KK + ++L ++ R L+N+ + +KQ Q T+VRL +
Sbjct: 704 VRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQ 763
Query: 303 L-EEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDV 361
+ EE EK +L S+ + + ++ K+ L + LE QK + +++ + +
Sbjct: 764 MKEEQEKARLTESRRNREIAQLKKDQRKRDHQL----RLLEAQKRNQEVVLRRKTEEVTA 819
Query: 362 LKRQ 365
L+RQ
Sbjct: 820 LRRQ 823
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 53.1 bits (126), Expect = 4e-07
Identities = 40/179 (22%), Positives = 82/179 (45%), Gaps = 11/179 (6%)
Query: 190 TEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQ 249
TE+++ L+ + H ++ L + + ++ + Q+K E+ + +Q +N +
Sbjct: 1069 TESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGK 1128
Query: 250 VEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKY 309
E + + + L+QQL + +NK +K + Q + + E+EK
Sbjct: 1129 QESVEERLSQLQSENMLLRQQLDDAHNKADNK---EKTVINIQDQFHAIVQKLQAESEKQ 1185
Query: 310 KLELSKLRQNNKDIANE-EHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKM 367
L L + NK++ +E H K + EN+K E++ ++ + Q +L D LK+Q M
Sbjct: 1186 SL---LLEERNKELISECNHLKERQYQYENEKAERE----VVVRQLQQELADTLKKQSM 1237
Score = 50.8 bits (120), Expect = 2e-06
Identities = 51/217 (23%), Positives = 99/217 (45%), Gaps = 35/217 (16%)
Query: 191 EAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQV 250
E ++ L+++ +++++LD+ + + KE + N++ Q + Q++
Sbjct: 1133 EERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQF----------HAIVQKLQAES 1182
Query: 251 EKYKTLFEEANKKYDGLQQQLSSVERELENK--------RRLQKQAASS---QSATEVRL 299
EK L EE NK+ L + + EN+ R+LQ++ A + QS +E L
Sbjct: 1183 EKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASL 1242
Query: 300 N-------RALEEAEKYKLELSKLR---QNNKDIANEEHKKIEVLKSENKKLEKQKGELM 349
+E + K +L ++R Q +D E + E ++ +KLEK +L
Sbjct: 1243 EVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLK 1302
Query: 350 IGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFMKAL 386
+ KKQ+ I+ L++ ++ LS E+E +K L
Sbjct: 1303 VTVKKQMDKIEELQKNLLNAN----LSEDEKEQLKKL 1335
Score = 36.6 bits (83), Expect = 0.040
Identities = 76/371 (20%), Positives = 149/371 (40%), Gaps = 62/371 (16%)
Query: 35 LEEEYKRL-NAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYS-LRGLLP 92
+EE K L NA L + D +Q K+++ +Q + K+ + E + + + LL
Sbjct: 1312 IEELQKNLLNANL---SEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLK 1368
Query: 93 ---------SEGIVHLHSETKPKTKNID-PVNKVQNKLHSANKGRKTNSSVKLKYSDVQT 142
G H + K +D +NK+++K+ +T S K + T
Sbjct: 1369 MTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGS---KCLHLDT 1425
Query: 143 ADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLH 202
+ + E S ++ K K+ Q ++ L + + ++ S + ++ Q++ K ++
Sbjct: 1426 KNQILQEELLSMKTVQKKCEKL--QKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIE 1483
Query: 203 VM-QEELDNVVCECNK---------------KEDEIQNLKSQVKNFEEDFMRQQRTINMQ 246
++E+ + E N +E+ ++KSQ++ +D + I
Sbjct: 1484 ERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTS 1543
Query: 247 Q-----SQVEKYKTLFEEANKKYDGLQQQLSSVER---ELENKRRLQKQAASSQSAT--- 295
Q +++EKYK L+ E K L +L+ E+ K ++KQ + S T
Sbjct: 1544 QEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTT 1603
Query: 296 --------------EVRLNRALEEAEKYKLELSKLRQNNKDIANEEHK-KIEVLKSENKK 340
+ LNR L E + S R +N + N K + E+ K+ ++
Sbjct: 1604 RPVMEPPCVGNLNNSLDLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRE 1663
Query: 341 LEKQKGELMIG 351
L++ EL G
Sbjct: 1664 LKEAAAELESG 1674
Score = 33.5 bits (75), Expect = 0.34
Identities = 59/291 (20%), Positives = 121/291 (41%), Gaps = 25/291 (8%)
Query: 72 VSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETKP----------KTKNIDPVNKVQNKLH 121
V Q++S DD DD + SE HS K + K+ + K+Q+
Sbjct: 674 VKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAAL 733
Query: 122 SANK--GRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYIDD 179
S + K N L + D V + + L++T +I+ QLE + + E+ +
Sbjct: 734 SCERLLELKKNHCELLTVKIKKMEDKVNVLQR----ELSET-KEIKSQLEHQKV-EWERE 787
Query: 180 IFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQ 239
+ S + E + R ++E+L + K+ + Q L+ ++ E +
Sbjct: 788 LCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTV 847
Query: 240 QRTIN-MQQSQVEKYKTLFEEANKKY--DGLQQQLSSVERELENKRRLQKQAASSQSATE 296
+ +N + Q + + + L E N + DG+ S ++E+E ++ S E
Sbjct: 848 KSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEE 907
Query: 297 VRLNRA----LEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEK 343
L+ EE +LE+ ++ N++ + + ++++K +N+ L+K
Sbjct: 908 KDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQK 958
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.339
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,110,904
Number of Sequences: 37866
Number of extensions: 647781
Number of successful extensions: 8369
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 305
Number of HSP's successfully gapped in prelim test: 849
Number of HSP's that attempted gapping in prelim test: 4751
Number of HSP's gapped (non-prelim): 3340
length of query: 391
length of database: 18,247,518
effective HSP length: 104
effective length of query: 287
effective length of database: 14,309,454
effective search space: 4106813298
effective search space used: 4106813298
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.