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Search of human proteins with 33946280
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo
sapiens]
(1147 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens] 2300 0.0
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens] 2268 0.0
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 88 5e-17
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 69 2e-11
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 69 3e-11
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 67 1e-10
gi|17975763 myelin transcription factor 1 [Homo sapiens] 66 2e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ... 65 3e-10
gi|38788274 bromodomain PHD finger transcription factor isoform ... 65 3e-10
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 65 5e-10
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 63 1e-09
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 63 1e-09
gi|21361639 DIPB protein [Homo sapiens] 63 1e-09
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 62 2e-09
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 62 3e-09
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 62 4e-09
gi|55956788 nucleolin [Homo sapiens] 61 7e-09
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 61 7e-09
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 60 9e-09
gi|115529449 upstream binding transcription factor, RNA polymera... 60 2e-08
gi|115529451 upstream binding transcription factor, RNA polymera... 60 2e-08
gi|7657671 upstream binding transcription factor, RNA polymerase... 60 2e-08
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 59 2e-08
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 59 3e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 58 5e-08
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 58 5e-08
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 58 5e-08
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 58 5e-08
gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 58 6e-08
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 57 8e-08
>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
Length = 1147
Score = 2300 bits (5961), Expect = 0.0
Identities = 1147/1147 (100%), Positives = 1147/1147 (100%)
Query: 1 MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG 60
MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG
Sbjct: 1 MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG 60
Query: 61 ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL 120
ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL
Sbjct: 61 ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL 120
Query: 121 TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR 180
TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR
Sbjct: 121 TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR 180
Query: 181 GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV 240
GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV
Sbjct: 181 GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV 240
Query: 241 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ 300
EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ
Sbjct: 241 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ 300
Query: 301 ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE 360
ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE
Sbjct: 301 ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE 360
Query: 361 IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL 420
IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL
Sbjct: 361 IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL 420
Query: 421 KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA 480
KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA
Sbjct: 421 KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA 480
Query: 481 GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL 540
GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL
Sbjct: 481 GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL 540
Query: 541 DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE 600
DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE
Sbjct: 541 DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE 600
Query: 601 YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT 660
YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT
Sbjct: 601 YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT 660
Query: 661 GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF 720
GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF
Sbjct: 661 GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF 720
Query: 721 FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR 780
FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR
Sbjct: 721 FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR 780
Query: 781 CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS 840
CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS
Sbjct: 781 CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS 840
Query: 841 KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN 900
KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN
Sbjct: 841 KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN 900
Query: 901 LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV 960
LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV
Sbjct: 901 LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV 960
Query: 961 IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL 1020
IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL
Sbjct: 961 IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL 1020
Query: 1021 LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT 1080
LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT
Sbjct: 1021 LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT 1080
Query: 1081 ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVSLPYNMHLI 1140
ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVSLPYNMHLI
Sbjct: 1081 ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVSLPYNMHLI 1140
Query: 1141 NDCSNTF 1147
NDCSNTF
Sbjct: 1141 NDCSNTF 1147
>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
Length = 1812
Score = 2268 bits (5876), Expect = 0.0
Identities = 1132/1137 (99%), Positives = 1135/1137 (99%)
Query: 1 MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG 60
MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG
Sbjct: 1 MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYG 60
Query: 61 ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL 120
ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL
Sbjct: 61 ETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNSKVNTDGLVLRGWYNCL 120
Query: 121 TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR 180
TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR
Sbjct: 121 TLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR 180
Query: 181 GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV 240
GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV
Sbjct: 181 GPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEV 240
Query: 241 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ 300
EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ
Sbjct: 241 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ 300
Query: 301 ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE 360
ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE
Sbjct: 301 ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE 360
Query: 361 IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL 420
IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL
Sbjct: 361 IEISRMKDQGPDKENSGAIEASVKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQL 420
Query: 421 KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA 480
KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA
Sbjct: 421 KNTKQDSLGQLVDWTMQALNLQVALRQPIALNVRQLKAGTKLVSSLAECGAQGVTGLLQA 480
Query: 481 GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL 540
GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL
Sbjct: 481 GVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNEKSGYQKLLELILL 540
Query: 541 DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE 600
DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE
Sbjct: 541 DQTVRVVTAGSAILQKCHFYEVLSEIKRLGDHLAEKTSSLPNHSEPDHDTDAGLERTNPE 600
Query: 601 YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT 660
YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT
Sbjct: 601 YENEVEASMDMDLLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARIT 660
Query: 661 GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF 720
GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF
Sbjct: 661 GPPERDDPYPVLFRYLHSHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLF 720
Query: 721 FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR 780
FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR
Sbjct: 721 FMSEYEATNLLIRALCHFYDQDEEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQR 780
Query: 781 CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS 840
CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS
Sbjct: 781 CTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYSKEALGDS 840
Query: 841 KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN 900
KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN
Sbjct: 841 KSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADENNAKLQELGKWLEPLKN 900
Query: 901 LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV 960
LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV
Sbjct: 901 LRFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQKDLKWNLAV 960
Query: 961 IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL 1020
IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL
Sbjct: 961 IQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTEL 1020
Query: 1021 LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT 1080
LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT
Sbjct: 1021 LRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLT 1080
Query: 1081 ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVSLPYNM 1137
ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQV P+++
Sbjct: 1081 ISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQTTQVIEPHDI 1137
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 87.8 bits (216), Expect = 5e-17
Identities = 67/223 (30%), Positives = 96/223 (43%), Gaps = 26/223 (11%)
Query: 127 SVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPR--- 183
S D V+ PP PPPPP P P P A SPP P P
Sbjct: 784 SDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTA----------SPPVPAKEEPEELP 833
Query: 184 TPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQ------YSDE 237
PGP PP PVP PV+ + P +P P + +
Sbjct: 834 AAPGPLPPPPPPPPPVPGPVTLPPPQLVPEG-------TPGGGGPPALEEDLTVININSS 886
Query: 238 GEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDG 297
E EEE++EE EE+E++ + EE+ +E+E+D EEEEE+ EEE EE+E ++
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Query: 298 YEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDP 340
E+ +E+ + ++E F +VE A ++PP P
Sbjct: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989
Score = 51.2 bits (121), Expect = 6e-06
Identities = 43/141 (30%), Positives = 59/141 (41%), Gaps = 10/141 (7%)
Query: 162 ADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVP-----LPVSGDKEEDAPHRED 216
A GE E+ G+PP P PP PP E +P P + G +EE
Sbjct: 968 AGGEVEE---GAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAP 1024
Query: 217 YFEPIS-PDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIP 275
P + P + V +EG+ G +E EE E +EEE ++ D + P
Sbjct: 1025 TLAPEALPSQGEVEREGESPAAGPPPQELVEE-EPSAPPTLLEEETEDGSDKVQPPPETP 1083
Query: 276 EEEEEDEEEEGEEDEEGEGDD 296
EEE + E E E +E E DD
Sbjct: 1084 AEEEMETETEAEALQEKEQDD 1104
Score = 32.0 bits (71), Expect = 3.5
Identities = 36/144 (25%), Positives = 49/144 (34%), Gaps = 21/144 (14%)
Query: 140 PPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRG---------PRTPPGPPP 190
P P P PPP P P + P H G + P P P PGPP
Sbjct: 646 PTPAPVPPPEAPSP-FRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPT 704
Query: 191 PDDDEDDPVPLPVS-------GDKEEDAPHRED-YFEPISPDRNSVPQEGQYSDEGEVEE 242
+ VP VS G + A ED P ++P + + G V
Sbjct: 705 TANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFG--GRVPR 762
Query: 243 EQ-QEEGEEDEDDVDVEEEEDEDE 265
+E+ DV++ E D D+
Sbjct: 763 PAFVHYDKEEASDVEISLESDSDD 786
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 69.3 bits (168), Expect = 2e-11
Identities = 38/139 (27%), Positives = 73/139 (52%), Gaps = 3/139 (2%)
Query: 208 EEDAPHREDYFEPISPDRNSVPQEGQYSD-EGEVEEEQQEEGEEDEDDVDVEEEEDEDED 266
E+ P +E+ P+ P+ ++ D E +E+ E+ E ++ ++V+E +E+E+
Sbjct: 477 EQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEE 536
Query: 267 DRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYT 326
+ + +EE E+EEEE E E EGD+ E++S ++D L+++ K + D EY
Sbjct: 537 EEEEEEE--DEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYD 594
Query: 327 AEDLASVPPMTYDPYDREL 345
++D + YD R +
Sbjct: 595 SDDDRTKEERAYDKAKRRI 613
Score = 54.3 bits (129), Expect = 7e-07
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 8/129 (6%)
Query: 179 PRGPRTPPGPPPPDDDED------DPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEG 232
P TPP P P+++ED D S ++ E + + E +E
Sbjct: 481 PEKEETPP-PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEE 539
Query: 233 QYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDE-DDRRTVDSIPEEEEEDEEEEGEEDEE 291
+ ++ E EEE++EEGE + + D E+E+ DE D +T+D P +E + E +D+
Sbjct: 540 EEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDR 599
Query: 292 GEGDDGYEQ 300
+ + Y++
Sbjct: 600 TKEERAYDK 608
Score = 34.7 bits (78), Expect = 0.53
Identities = 37/180 (20%), Positives = 75/180 (41%), Gaps = 29/180 (16%)
Query: 158 NPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPV-------SGDKEED 210
N G++ D+F S + Q + + PGP +EDD + + KE +
Sbjct: 181 NSSGESGDESDEFLQSR-KGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERE 239
Query: 211 APHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEE--------DEDDVDVEEE-- 260
R++ + + E D+ + +E Q++ EE D + EE
Sbjct: 240 RKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKA 299
Query: 261 ------EDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
ED++E D++ D ++ E++E+E +E ++G + + ++ +A L+ E
Sbjct: 300 ETPTAAEDDNEGDKKKKDKKKKKGEKEEKE--KEKKKGPSK---ATVKAMQEALAKLKEE 354
Score = 33.5 bits (75), Expect = 1.2
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
Query: 230 QEGQYSDEGEVEEEQQEEGEEDEDDVDVEE---EEDEDEDDRRTVDSIPEEEEEDEEEEG 286
QE Q S + +E+++++ +ED+ ++EE E + DR TV P E +EEE
Sbjct: 35 QEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKP--TENNEEEFT 92
Query: 287 EEDEEGEGDDGYEQISSDED 306
+D++ +G G +Q D D
Sbjct: 93 SKDKKKKGQKGKKQSFDDND 112
Score = 33.5 bits (75), Expect = 1.2
Identities = 24/104 (23%), Positives = 55/104 (52%), Gaps = 11/104 (10%)
Query: 220 PISPDRNSVPQEGQYSDEGEVE--EEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEE 277
P S ++ P + +EG+ + ++++++GE++E +E+E + + TV ++ E
Sbjct: 293 PASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEE-----KEKEKKKGPSKATVKAMQEA 347
Query: 278 ----EEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFK 317
+EE+E ++ EE+E + + E +E+ + +RE K
Sbjct: 348 LAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKK 391
Score = 32.7 bits (73), Expect = 2.0
Identities = 51/261 (19%), Positives = 101/261 (38%), Gaps = 37/261 (14%)
Query: 192 DDDEDDPVPLPVSG-----DKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGE---VEEE 243
DDD+ + +P G +K+ D ++ +R+ + G+ DE + +
Sbjct: 139 DDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRK 198
Query: 244 QQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEE----------GE 293
Q++ ++++ ++E ++D+ + ++ E+ E E + DEE E
Sbjct: 199 GQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEE 258
Query: 294 GDDGYEQISSDEDGIADLERETFKYP---NFDVEYTAEDLASVPPMTYDPYDRELVPLLY 350
+ G + S ++ E ET K + V +E+ A P D + +
Sbjct: 259 LETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKK-- 316
Query: 351 FSCPYKTTFEIEISRMKDQGPDKENSGAI-EASVKLTELLDLYREDRGAKWVTALEEIPS 409
K + E + K +GP K A+ EA KL E + + + +
Sbjct: 317 -DKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER---------- 365
Query: 410 LIIKGLSYLQLKNTKQDSLGQ 430
IK L L+ K +++ L Q
Sbjct: 366 --IKRLEELEAKRKEEERLEQ 384
Score = 31.2 bits (69), Expect = 5.9
Identities = 30/138 (21%), Positives = 62/138 (44%), Gaps = 6/138 (4%)
Query: 241 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ 300
EEE++++ EE+E +EE E + +++ R + +E+ E ++++ +E +E +G
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEER----LEQEKRERKKQKEKERKERLKKEGKLL 408
Query: 301 ISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFE 360
S + A E VE ++D Y+ R+ +P S + E
Sbjct: 409 TKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESME 468
Query: 361 I--EISRMKDQGPDKENS 376
+ + M+ P+KE +
Sbjct: 469 LCAAVEVMEQGVPEKEET 486
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 68.9 bits (167), Expect = 3e-11
Identities = 51/189 (26%), Positives = 85/189 (44%), Gaps = 27/189 (14%)
Query: 142 PPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPL 201
PP P P Q +++ + ++G+ SP R + T P +++ +
Sbjct: 1276 PPETPMEPDEQVTVEEQKETSEGKTSP----SPIRIEEEVKETGEALLPQEENRREETCA 1331
Query: 202 PVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEE 261
PVS + +D +P +E + +E E EEE++EEGEE+E +VE++
Sbjct: 1332 PVSPNTSPGEKPEDDLIKP---------EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDP 1382
Query: 262 D-------------EDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGI 308
D +++D +D EEEEEDEE ED + + +D + S E
Sbjct: 1383 DGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDD-SHMESAEVEK 1441
Query: 309 ADLERETFK 317
+L RE+FK
Sbjct: 1442 EELPRESFK 1450
Score = 53.1 bits (126), Expect = 1e-06
Identities = 29/63 (46%), Positives = 40/63 (63%), Gaps = 8/63 (12%)
Query: 227 SVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEG 286
S P G+ E+ +E EE EE+ED+ + EEEE+E+ED+ EEEEE+EEEE
Sbjct: 1051 SRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDE--------EEEEEEEEEEE 1102
Query: 287 EED 289
EE+
Sbjct: 1103 EEN 1105
Score = 51.2 bits (121), Expect = 6e-06
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 18/115 (15%)
Query: 236 DEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGD 295
+ G++ E +E EE+E++ D EEEE+E+E EEE+E+EEEE EE+EE E
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEE----------EEEDEEEEEEEEEEEEEENI 1106
Query: 296 DGYEQISSDEDGIADLERETF--------KYPNFDVEYTAEDLASVPPMTYDPYD 342
+ +A + F K + T E ++ + +P+D
Sbjct: 1107 QSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFD 1161
Score = 48.9 bits (115), Expect = 3e-05
Identities = 29/66 (43%), Positives = 40/66 (60%), Gaps = 14/66 (21%)
Query: 220 PISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEE 279
P++ +R + + + S E E EEE +EE EE+E EEEEDE+E+ EEEE
Sbjct: 1053 PVTGERGQLLELSKESSEEEEEEEDEEEEEEEE-----EEEEDEEEE---------EEEE 1098
Query: 280 EDEEEE 285
E+EEEE
Sbjct: 1099 EEEEEE 1104
Score = 33.5 bits (75), Expect = 1.2
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 7/73 (9%)
Query: 198 PVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDV 257
P PV+G+ R E +E +E E EEE+++E EE+E++ +
Sbjct: 1049 PESRPVTGE-------RGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEE 1101
Query: 258 EEEEDEDEDDRRT 270
EEE + R T
Sbjct: 1102 EEENIQSSPPRLT 1114
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 66.6 bits (161), Expect = 1e-10
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 18/165 (10%)
Query: 176 RPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHRE-DYFEPISPDRNSVPQEGQY 234
+PQ P+ P D D D ED +E D E S D + E +
Sbjct: 67 QPQEPAPKRKPFAVKADSSSVDECD---DSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEE 123
Query: 235 SDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEG 294
+EG+ EEE++ E E+++DD D E+ EDE+E EEEEE+EEEE EE+E+ +
Sbjct: 124 DEEGDREEEEEIEEEDEDDDEDGEDVEDEEE----------EEEEEEEEEEEEENEDHQM 173
Query: 295 DDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYD 339
+ +I D + + +Y N+D E A+ L ++ + D
Sbjct: 174 NCHNTRIMQDTE---KDDNNNDEYDNYD-ELVAKSLLNLGKIAED 214
Score = 37.0 bits (84), Expect = 0.11
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 12/104 (11%)
Query: 211 APHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRT 270
A HR Y P++ R + ++ Q + + + D VD ++ D ED
Sbjct: 47 ARHRSVYGCPLAKKRKTQDKQPQEP----APKRKPFAVKADSSSVDECDDSDGTED---- 98
Query: 271 VDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
+E+EEDE EE ED + GD+ E D + ++E E
Sbjct: 99 ----MDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE 138
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 66.2 bits (160), Expect = 2e-10
Identities = 36/77 (46%), Positives = 52/77 (67%), Gaps = 6/77 (7%)
Query: 227 SVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEG 286
S Q+G S E E EEE++EE EE+ED+ + EEEE+E+E++ EEEEE+EEEE
Sbjct: 248 SSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEE------EEEEEEEEEEE 301
Query: 287 EEDEEGEGDDGYEQISS 303
EE+EE D +++ +S
Sbjct: 302 EEEEEAAPDVIFQEDTS 318
Score = 56.6 bits (135), Expect = 1e-07
Identities = 31/82 (37%), Positives = 50/82 (60%), Gaps = 11/82 (13%)
Query: 233 QYSDEGEVEEEQQEEG---EEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED 289
Q ++ EE +++G E+ED+ + EEEE+E+ED+ EEEEE+EEEE EE+
Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDE--------EEEEEEEEEEEEEE 289
Query: 290 EEGEGDDGYEQISSDEDGIADL 311
EE E ++ E+ +E+ D+
Sbjct: 290 EEEEEEEEEEEEEEEEEAAPDV 311
Score = 45.1 bits (105), Expect = 4e-04
Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 231 EGQYSDEGE----VEEEQQEE----GEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDE 282
EG S+EGE ++ E EE E D+ + ED ++ I EEEDE
Sbjct: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262
Query: 283 EEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
EEE EE+EE E ++ E+ +E+ + E E
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE 294
Score = 40.0 bits (92), Expect = 0.013
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 213 HREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVD 272
H E+ E + E + +E E EEE++EE EE+E++ + EEEE+ D D
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
Query: 273 SIPEEEEEDEEEEGEEDEEGEGD-DGYEQISSDED 306
+ ++ E G E + + ++ SD+D
Sbjct: 317 TSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDD 351
Score = 38.9 bits (89), Expect = 0.028
Identities = 27/113 (23%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 206 DKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDE 265
+ EE+ E+ E + +E + +E E EEE++EE EE+E DV +ED
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319
Query: 266 DDRRTVDSI-------PEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADL 311
+ + P+ E E +D++ E + +DE + D+
Sbjct: 320 TSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDM 372
Score = 37.4 bits (85), Expect = 0.082
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 11/110 (10%)
Query: 233 QYSDEGEVEEEQQE----EGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEE-------D 281
Q + EG EE ++ + E+ E+ V+V E +D + D+ EE + +
Sbjct: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
Query: 282 EEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLA 331
EE+E EE+EE E ++ E+ +E+ + E E + + E E+ A
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/174 (31%), Positives = 75/174 (43%), Gaps = 20/174 (11%)
Query: 135 DRDSPPPPPPPPPPPQ-PQPSLKRNPK--------HADGEKEDQFNGSPPRPQPRGPRTP 185
+R +P PPPPPPPP P L+ + A E + S PR R P
Sbjct: 18 ERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKP 77
Query: 186 PGPPPPDDDEDDP-VPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQ 244
P PPP P G + + R +V + V ++
Sbjct: 78 PPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRAVNK--------VVYDDH 129
Query: 245 QEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED--EEGEGDD 296
+ E EE+E+D+ EEEE+ED D T DS +EE+E EE++ + D EE E DD
Sbjct: 130 ESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDD 183
Score = 42.4 bits (98), Expect = 0.003
Identities = 51/202 (25%), Positives = 66/202 (32%), Gaps = 58/202 (28%)
Query: 140 PPPPPPPPPPQPQPSLKRNPKH----------ADGEKEDQFNGSPPRPQPRGPRTPPGPP 189
P PPPPPPPP P +H A E + S PR R PP PP
Sbjct: 22 PAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPP-PP 80
Query: 190 PPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGE 249
PP +P S P G G G
Sbjct: 81 PP------------------------------APPSTSAPGRGGRGGGGGRTGGGGGGGH 110
Query: 250 EDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED---EEGEGDDGYEQISSDED 306
RR V+ + ++ E EEEE EED EE E +DG + + D +
Sbjct: 111 LARTTAA-----------RRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSE 159
Query: 307 GIADLERETFKYPNFDVEYTAE 328
D E + + + D +Y E
Sbjct: 160 ---DDEEDEMEEDDDDSDYPEE 178
Score = 37.0 bits (84), Expect = 0.11
Identities = 19/75 (25%), Positives = 39/75 (52%), Gaps = 1/75 (1%)
Query: 230 QEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED 289
++G + EE ++++ E + D D E+ +E ED DS ++ +D+ E+G+ +
Sbjct: 563 KKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDS-DDKTPDDDPEQGKSE 621
Query: 290 EEGEGDDGYEQISSD 304
E E D +S++
Sbjct: 622 EPTEVGDKGNSVSAN 636
Score = 31.2 bits (69), Expect = 5.9
Identities = 10/19 (52%), Positives = 14/19 (73%)
Query: 138 SPPPPPPPPPPPQPQPSLK 156
+PP PP PPP P P P+++
Sbjct: 2659 APPAPPAPPPSPPPPPAVQ 2677
Score = 30.8 bits (68), Expect = 7.7
Identities = 17/71 (23%), Positives = 38/71 (53%)
Query: 235 SDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEG 294
++E +E + ++G+ D E E+D++E + + D+ EE +++ ++ ++
Sbjct: 552 ANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTP 611
Query: 295 DDGYEQISSDE 305
DD EQ S+E
Sbjct: 612 DDDPEQGKSEE 622
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/174 (31%), Positives = 75/174 (43%), Gaps = 20/174 (11%)
Query: 135 DRDSPPPPPPPPPPPQ-PQPSLKRNPK--------HADGEKEDQFNGSPPRPQPRGPRTP 185
+R +P PPPPPPPP P L+ + A E + S PR R P
Sbjct: 18 ERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKP 77
Query: 186 PGPPPPDDDEDDP-VPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQ 244
P PPP P G + + R +V + V ++
Sbjct: 78 PPPPPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLARTTAARRAVNK--------VVYDDH 129
Query: 245 QEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED--EEGEGDD 296
+ E EE+E+D+ EEEE+ED D T DS +EE+E EE++ + D EE E DD
Sbjct: 130 ESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDD 183
Score = 42.4 bits (98), Expect = 0.003
Identities = 51/202 (25%), Positives = 66/202 (32%), Gaps = 58/202 (28%)
Query: 140 PPPPPPPPPPQPQPSLKRNPKH----------ADGEKEDQFNGSPPRPQPRGPRTPPGPP 189
P PPPPPPPP P +H A E + S PR R PP PP
Sbjct: 22 PAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPP-PP 80
Query: 190 PPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGE 249
PP +P S P G G G
Sbjct: 81 PP------------------------------APPSTSAPGRGGRGGGGGRTGGGGGGGH 110
Query: 250 EDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED---EEGEGDDGYEQISSDED 306
RR V+ + ++ E EEEE EED EE E +DG + + D +
Sbjct: 111 LARTTAA-----------RRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSE 159
Query: 307 GIADLERETFKYPNFDVEYTAE 328
D E + + + D +Y E
Sbjct: 160 ---DDEEDEMEEDDDDSDYPEE 178
Score = 32.0 bits (71), Expect = 3.5
Identities = 15/60 (25%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 230 QEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED 289
++G + EE ++++ E + D D E+ +E ED DS ++ +D+ E+G+ +
Sbjct: 563 KKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDS-DDKTPDDDPEQGKSE 621
Score = 31.2 bits (69), Expect = 5.9
Identities = 10/19 (52%), Positives = 14/19 (73%)
Query: 138 SPPPPPPPPPPPQPQPSLK 156
+PP PP PPP P P P+++
Sbjct: 2676 APPAPPAPPPSPPPPPAVQ 2694
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 64.7 bits (156), Expect = 5e-10
Identities = 44/156 (28%), Positives = 75/156 (48%), Gaps = 3/156 (1%)
Query: 160 KHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHRED-YF 218
+ +GE+E + + + R + G D E + G+++E+ E
Sbjct: 762 EEVEGEREKE--EGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEV 819
Query: 219 EPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEE 278
E +R +EG+ +E EE++ EGEE+E + EEE +E E + + E E
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGE 879
Query: 279 EEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
EE+ E EGEE+ EGEG++ + +E+G + E E
Sbjct: 880 EEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915
Score = 62.4 bits (150), Expect = 2e-09
Identities = 44/151 (29%), Positives = 72/151 (47%), Gaps = 11/151 (7%)
Query: 160 KHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFE 219
+ +GE E++ G + G G +++E + + E + E E
Sbjct: 881 EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE 940
Query: 220 PISPDRNSVPQEGQYS---DEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPE 276
+ +EG++ +EGE E E++ EGE +E + + EEEE E E + E
Sbjct: 941 GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE-------E 993
Query: 277 EEEEDEEEEGEEDEEGEGDDGYEQISSDEDG 307
E EE+ EEEGE +EEGEG +G E+ + +G
Sbjct: 994 EGEEEGEEEGEGEEEGEG-EGEEEEEGEVEG 1023
Score = 60.5 bits (145), Expect = 9e-09
Identities = 46/156 (29%), Positives = 71/156 (45%), Gaps = 7/156 (4%)
Query: 160 KHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFE 219
+ +GE E++ G + G G + E++ G+ E + E E
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE------EGEGEGEDGEGEGEEE 951
Query: 220 PISPDRNSVPQEGQYSDEGEVEEEQQE-EGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEE 278
+ EG+ +EGE E E+ E EGEE+E + + EEEE E+E + E
Sbjct: 952 EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011
Query: 279 EEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
E +EEEEGE + E EG++G + +E ERE
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEERE 1047
Score = 60.1 bits (144), Expect = 1e-08
Identities = 42/155 (27%), Positives = 73/155 (47%), Gaps = 2/155 (1%)
Query: 165 EKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPD 224
E+E ++ G + G G + E + G++EE E+ E
Sbjct: 950 EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG 1009
Query: 225 RNSVPQEGQYSDEGEVEEEQQE-EGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDE- 282
+E + EGEVE E+ E EGEE+E + + EE E E E + + EEEEE +
Sbjct: 1010 EGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKY 1069
Query: 283 EEEGEEDEEGEGDDGYEQISSDEDGIADLERETFK 317
+E GEE+ E + + Y+++S + + + +T++
Sbjct: 1070 QETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQ 1104
Score = 59.3 bits (142), Expect = 2e-08
Identities = 44/114 (38%), Positives = 62/114 (54%), Gaps = 6/114 (5%)
Query: 205 GDKEEDAPHREDYFEPISPDRNSVPQEGQYSDE---GEVEEEQQEEGEEDEDDVDVEEEE 261
G++EE E+ E + EG+ +E GE EEE + EGEE+E + + EEE
Sbjct: 849 GEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE-GEEE 907
Query: 262 DEDEDDRRTVDSIPEEEEEDEEEEGEEDE-EGEGDDGYEQISSDEDGIADLERE 314
E E + + EEE E+ E EGEE+E EGEG+DG E +E+G + E E
Sbjct: 908 GEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG-EGEGEEEEGEWEGEEE 960
Score = 58.5 bits (140), Expect = 3e-08
Identities = 58/189 (30%), Positives = 86/189 (45%), Gaps = 18/189 (9%)
Query: 156 KRNPKHADGEKE-DQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHR 214
+R K GE+E DQ G + RG G + ++ ++EE+
Sbjct: 779 ERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKG--EREEEEEEGEGE 836
Query: 215 EDYFEPISPDRNSVPQEGQ-----YSDEGEVEEEQQE---EGEEDEDDVDVEEE-EDEDE 265
E+ E + +EG+ +EGE EEE +E EGEE+E + + EEE E E E
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896
Query: 266 DDRRTVDSIPEEEEEDEEEEGE-----EDEEGEGDDGYEQISSD-EDGIADLERETFKYP 319
++ + E E E EEEEGE E EEGEG+ E+ + EDG + E E ++
Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE 956
Query: 320 NFDVEYTAE 328
+ E E
Sbjct: 957 GEEEEGEGE 965
Score = 53.9 bits (128), Expect = 9e-07
Identities = 40/113 (35%), Positives = 62/113 (54%), Gaps = 4/113 (3%)
Query: 205 GDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQE-EGE-EDEDDVDVEEEED 262
G++E + E+ E + EG+ +EGE E E++E EGE E+E + + EEEE
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917
Query: 263 EDEDDRRTVDSIPEEEEEDEEEEGEEDE-EGEGDDGYEQISSDEDGIADLERE 314
E + + + E EEE+ E EGE+ E EGE ++G E +E+G + E E
Sbjct: 918 EGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEG-EWEGEEEEGEGEGEEE 969
Score = 52.8 bits (125), Expect = 2e-06
Identities = 48/166 (28%), Positives = 74/166 (44%), Gaps = 16/166 (9%)
Query: 156 KRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPP-------DDDEDDPVPLPVSGDKE 208
K K DGE+++Q + R G + D ++ G +E
Sbjct: 699 KEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEE 758
Query: 209 EDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDR 268
+ E E +R + G+ ++GE EE Q EGEE+E + EE+E+ E +
Sbjct: 759 GEGEEVEGEREKEEGERKKEERAGK-EEKGE-EEGDQGEGEEEETEGRGEEKEEGGEVEG 816
Query: 269 RTVD------SIPEEEEEDEEEEGE-EDEEGEGDDGYEQISSDEDG 307
V+ EEE E EEEEGE E+EEGEG++ + +E+G
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEG 862
Score = 50.8 bits (120), Expect = 7e-06
Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 15/162 (9%)
Query: 160 KHADGEKE-DQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYF 218
+ +GE+E ++ G + G G +++E + G++E + E+
Sbjct: 863 EEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG-----EGEEEGEGEGEEEEG 917
Query: 219 EPISPDRNSVPQEGQYSDEGEVEEEQQE-EGEEDEDDVDVEEEEDEDEDDRRTVDSIPEE 277
E + + +EGE E E E EGEE+E + + EEEE E E + E
Sbjct: 918 EGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE--GE 975
Query: 278 EEEDE--EEEGE---EDEEGEGDDGYEQISSDEDGIADLERE 314
E E E EEEGE E+EEGE ++G E+ +E+G + E E
Sbjct: 976 EGEGEGEEEEGEGEGEEEEGE-EEGEEEGEGEEEGEGEGEEE 1016
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/89 (34%), Positives = 47/89 (52%), Gaps = 4/89 (4%)
Query: 230 QEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED 289
+EG +E E E E +EEGE +E + + E+EE E + + R EEE D+ E EE+
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEE 800
Query: 290 EEGEGDD----GYEQISSDEDGIADLERE 314
EG G++ G + E+G + E E
Sbjct: 801 TEGRGEEKEEGGEVEGGEVEEGKGEREEE 829
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/102 (27%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
Query: 202 PVSGDKE---EDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVE 258
P G+KE ++ + D E +R Q+ + + E EE+ EGEE+E D + E
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
Query: 259 EEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ 300
EE++ + + + + E E++E E +E+ G+ + G E+
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790
Score = 44.7 bits (104), Expect = 5e-04
Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 9/120 (7%)
Query: 207 KEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEE-EDEDE 265
+E++ RE + +RN +EG + GE EEE+ + EE+E + + +EE E E+
Sbjct: 708 EEQEQKEREQGHQK---ERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEV 764
Query: 266 DDRRTVDSIPEEEEEDEEEEGEEDE-EGEGDDGYEQISSDEDGIADLERETFKYPNFDVE 324
+ R + E E + EE G+E++ E EGD G E + +G + + E + +VE
Sbjct: 765 EGEREKE---EGERKKEERAGKEEKGEEEGDQG-EGEEEETEGRGEEKEEGGEVEGGEVE 820
Score = 41.6 bits (96), Expect = 0.004
Identities = 23/81 (28%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Query: 236 DEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEG- 294
D+G E E+ EGE++ + + ++ D +E +++ + ++E E EEG E+E GEG
Sbjct: 680 DKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGE 739
Query: 295 -DDGYEQISSDEDGIADLERE 314
++G + +++G E E
Sbjct: 740 EEEGDREEEEEKEGEGKEEGE 760
Score = 39.7 bits (91), Expect = 0.017
Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 7/87 (8%)
Query: 229 PQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEE-EDEEEEG- 286
P EG+ + E EE ++ +GEE E E E+ ++ + ++ EEE E EEEEG
Sbjct: 689 PGEGE-KELAEKEEWKKRDGEEQEQK---EREQGHQKERNQEMEEGGEEEHGEGEEEEGD 744
Query: 287 -EEDEEGEGDDGYEQISSDEDGIADLE 312
EE+EE EG+ E + +G + E
Sbjct: 745 REEEEEKEGEGKEEGEGEEVEGEREKE 771
Score = 38.5 bits (88), Expect = 0.037
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 18/98 (18%)
Query: 234 YSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTV------------DSIPEEEEED 281
+SDE EVE +++EG ED +EE+E E ++ V D + ++ E
Sbjct: 579 FSDE-EVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVS 637
Query: 282 EEE-----EGEEDEEGEGDDGYEQISSDEDGIADLERE 314
E + E E+ EG GD E+ SS + D ERE
Sbjct: 638 EGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEERE 675
Score = 37.7 bits (86), Expect = 0.063
Identities = 20/76 (26%), Positives = 41/76 (53%)
Query: 232 GQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEE 291
G+ GE E+E E+ E + D + +E+++ ++ ++ + EE E+E EGEE+E
Sbjct: 684 GEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEG 743
Query: 292 GEGDDGYEQISSDEDG 307
++ ++ E+G
Sbjct: 744 DREEEEEKEGEGKEEG 759
Score = 32.7 bits (73), Expect = 2.0
Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 1/123 (0%)
Query: 196 DDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDV 255
D+ V +P + ED+ + + + +V G ++ E+ + + E +
Sbjct: 581 DEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGK 640
Query: 256 DVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADL-ERE 314
E ED + R + E E + EE E+GE D G ++ +G +L E+E
Sbjct: 641 AKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKE 700
Query: 315 TFK 317
+K
Sbjct: 701 EWK 703
Score = 31.2 bits (69), Expect = 5.9
Identities = 28/108 (25%), Positives = 50/108 (46%), Gaps = 16/108 (14%)
Query: 214 REDYFEPISPDRNSVPQ--EGQYSDEGEVEEEQQ-------EEGEEDEDD-VDVEEEEDE 263
R++ E +S D + EG+ GE E+ + EEG + D E E+ E
Sbjct: 619 RKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGE 678
Query: 264 DEDDRRTVDSIPE------EEEEDEEEEGEEDEEGEGDDGYEQISSDE 305
+ R ++ E E+EE ++ +GEE E+ E + G+++ + E
Sbjct: 679 KDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQE 726
>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 63.2 bits (152), Expect = 1e-09
Identities = 41/122 (33%), Positives = 66/122 (54%), Gaps = 24/122 (19%)
Query: 191 PDDDEDDPVPLPVSG-DKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQE-EG 248
P+D E V G DKEE+ ED +++ ++G+ + E E+E ++ EG
Sbjct: 170 PEDQEAPDSDAQVDGVDKEEEDEEGED-------EKDXENEDGEEEELDEEEDEDEDVEG 222
Query: 249 EEDEDDVDVEEEE---DEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDE 305
++D+D+V EEEE D+DEDD EDE+E+ EE+E G+G++ + +E
Sbjct: 223 DDDKDEVSEEEEEFGLDKDEDD------------EDEDEDEEEEESGKGENRKRETDDEE 270
Query: 306 DG 307
DG
Sbjct: 271 DG 272
Score = 57.0 bits (136), Expect = 1e-07
Identities = 28/71 (39%), Positives = 46/71 (64%), Gaps = 2/71 (2%)
Query: 236 DEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGD 295
D + E+++ + + D VD EEE++E ED++ + EEEE DEEE +EDE+ EGD
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEE--DEDEDVEGD 223
Query: 296 DGYEQISSDED 306
D +++S +E+
Sbjct: 224 DDKDEVSEEEE 234
Score = 46.6 bits (109), Expect = 1e-04
Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 7/87 (8%)
Query: 230 QEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED 289
QE SD +++EE EE ED+ D E E+ E+E+ +D E+E+ED E + ++D
Sbjct: 173 QEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEE----LDE-EEDEDEDVEGDDDKD 227
Query: 290 E--EGEGDDGYEQISSDEDGIADLERE 314
E E E + G ++ DED D E E
Sbjct: 228 EVSEEEEEFGLDKDEDDEDEDEDEEEE 254
Score = 40.4 bits (93), Expect = 0.010
Identities = 26/65 (40%), Positives = 38/65 (58%), Gaps = 4/65 (6%)
Query: 253 DDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLE 312
D D E++E D D + VD + ++EEEDEE E E+D E E D E++ +ED D+E
Sbjct: 166 DTYDPEDQEAPDSDAQ--VDGV-DKEEEDEEGEDEKDXENE-DGEEEELDEEEDEDEDVE 221
Query: 313 RETFK 317
+ K
Sbjct: 222 GDDDK 226
>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
phosphoprotein 32 family, member B [Homo sapiens]
Length = 272
Score = 63.2 bits (152), Expect = 1e-09
Identities = 41/122 (33%), Positives = 66/122 (54%), Gaps = 24/122 (19%)
Query: 191 PDDDEDDPVPLPVSG-DKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQE-EG 248
P+D E V G DKEE+ ED +++ ++G+ + E E+E ++ EG
Sbjct: 170 PEDQEAPDSDAQVDGVDKEEEDEEGED-------EKDXENEDGEEEELDEEEDEDEDVEG 222
Query: 249 EEDEDDVDVEEEE---DEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDE 305
++D+D+V EEEE D+DEDD EDE+E+ EE+E G+G++ + +E
Sbjct: 223 DDDKDEVSEEEEEFGLDKDEDD------------EDEDEDEEEEESGKGENRKRETDDEE 270
Query: 306 DG 307
DG
Sbjct: 271 DG 272
Score = 57.0 bits (136), Expect = 1e-07
Identities = 28/71 (39%), Positives = 46/71 (64%), Gaps = 2/71 (2%)
Query: 236 DEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGD 295
D + E+++ + + D VD EEE++E ED++ + EEEE DEEE +EDE+ EGD
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEE--DEDEDVEGD 223
Query: 296 DGYEQISSDED 306
D +++S +E+
Sbjct: 224 DDKDEVSEEEE 234
Score = 46.6 bits (109), Expect = 1e-04
Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 7/87 (8%)
Query: 230 QEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED 289
QE SD +++EE EE ED+ D E E+ E+E+ +D E+E+ED E + ++D
Sbjct: 173 QEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEE----LDE-EEDEDEDVEGDDDKD 227
Query: 290 E--EGEGDDGYEQISSDEDGIADLERE 314
E E E + G ++ DED D E E
Sbjct: 228 EVSEEEEEFGLDKDEDDEDEDEDEEEE 254
Score = 40.4 bits (93), Expect = 0.010
Identities = 26/65 (40%), Positives = 38/65 (58%), Gaps = 4/65 (6%)
Query: 253 DDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLE 312
D D E++E D D + VD + ++EEEDEE E E+D E E D E++ +ED D+E
Sbjct: 166 DTYDPEDQEAPDSDAQ--VDGV-DKEEEDEEGEDEKDXENE-DGEEEELDEEEDEDEDVE 221
Query: 313 RETFK 317
+ K
Sbjct: 222 GDDDK 226
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 63.2 bits (152), Expect = 1e-09
Identities = 50/178 (28%), Positives = 83/178 (46%), Gaps = 17/178 (9%)
Query: 231 EGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDE 290
EG +E EV+ EQ+ E E + + EEE E E++ T + +E +E+ EE+ EE+
Sbjct: 74 EGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEM 133
Query: 291 EGEGDDGYEQISSDEDGIADLERETFKYPNFD--VEYTAEDLA-------SVPPMTYDPY 341
E E + E+ + E+G ++ E ET FD +E AE +A + TY
Sbjct: 134 EDEQESEAEE-DNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQE 192
Query: 342 DRELVPLLYFSCPYKTTFE----IEISRMKDQGPDKENSGAIEASVKLTELLDLYRED 395
DR+L+ +L CP + + ++ K++ G A ++L E L D
Sbjct: 193 DRQLICVL---CPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSD 247
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 62.4 bits (150), Expect = 2e-09
Identities = 77/355 (21%), Positives = 142/355 (40%), Gaps = 41/355 (11%)
Query: 160 KHADGEKEDQFNGS----PPRPQP-------RGPRTPPGPPPPDDDEDDPVPLPVSGDKE 208
K D +++ + + S P + QP R P P PD E + + +
Sbjct: 107 KRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRS 166
Query: 209 EDAPHREDYFEPISPDR------NSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEED 262
+ E E D +S Q +E E EE EE EE E+D + +EE D
Sbjct: 167 SQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVD 226
Query: 263 EDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFD 322
ED ++ + EEEEE+EEEE E+DE + ++G + + E +D E+ + +
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE--ASDSGSESVSFTDGS 284
Query: 323 VEYTAEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAIEAS 382
V + S R + P+++ + +G+ +
Sbjct: 285 VRSGSGTDGSDEKKKERKRARGISPIVF--------------DRSGSSASESYAGSEKKH 330
Query: 383 VKLTELLDLYREDRGAKWVTALEEIPSLIIKGLSYLQLKNTKQDSLGQLVDWTMQALNLQ 442
KL+ + R+D+ +K L++ +IK ++ + K + + + LNL
Sbjct: 331 EKLSSSVRAVRKDQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLA 390
Query: 443 VALRQPIAL--NVRQLK--AGTKLVSSLAECGAQGVTGLLQAG----VISGLFEL 489
+ + L +VR+ G +SS + G + +L AG ++ G+F++
Sbjct: 391 FRSARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKI 445
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 62.0 bits (149), Expect = 3e-09
Identities = 38/108 (35%), Positives = 59/108 (54%), Gaps = 9/108 (8%)
Query: 210 DAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEG-------EEDEDDVDVEEEED 262
D RED P S E + +EGE EE++ +E EED++D DVE +ED
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205
Query: 263 EDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIAD 310
+DE + +EE+EDE+E+ EE+E G+G+ + +D++G D
Sbjct: 206 DDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEK--RKRETDDEGEDD 251
Score = 57.4 bits (137), Expect = 8e-08
Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 234 YSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGE 293
Y D + E+++ + + + D VD EEE++E ED+ D EEEE DEE++ +ED EG+
Sbjct: 144 YLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGD 203
Query: 294 GDDGYEQISSDED 306
DD +++S +E+
Sbjct: 204 EDD--DEVSEEEE 214
Score = 55.1 bits (131), Expect = 4e-07
Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 6/87 (6%)
Query: 230 QEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED 289
+E Q + + + E + +E EEDE+ D E+E+DED ++ + EE++EDE+ EG+ED
Sbjct: 150 REDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEE----EEFDEEDDEDEDVEGDED 205
Query: 290 EE--GEGDDGYEQISSDEDGIADLERE 314
++ E ++ + DED D E E
Sbjct: 206 DDEVSEEEEEFGLDEEDEDEDEDEEEE 232
Score = 52.4 bits (124), Expect = 2e-06
Identities = 32/106 (30%), Positives = 53/106 (50%), Gaps = 12/106 (11%)
Query: 193 DDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQE-EGEED 251
D ED P D E D E+ E + + ++G+ + E ++E ++ EG+ED
Sbjct: 149 DREDQEAP---DSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205
Query: 252 EDDVDVEEEE--------DEDEDDRRTVDSIPEEEEEDEEEEGEED 289
+D+V EEEE DEDED+ E+ + + ++EGE+D
Sbjct: 206 DDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251
Score = 41.2 bits (95), Expect = 0.006
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 33/104 (31%)
Query: 192 DDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEED 251
DD++ + D++ED EG D+ EV EE++E G ++
Sbjct: 181 DDEDGEEEEFDEEDDEDEDV-------------------EGD-EDDDEVSEEEEEFGLDE 220
Query: 252 EDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGD 295
ED E+EDEDE++ EE + E+ + E D+EGE D
Sbjct: 221 ED-----EDEDEDEEE--------EEGGKGEKRKRETDDEGEDD 251
Score = 32.3 bits (72), Expect = 2.7
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 11/81 (13%)
Query: 192 DDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEED 251
++DEDD +EE+ +D E + D + + + G EE++ E+ +E+
Sbjct: 177 EEDEDD------EDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEE 230
Query: 252 ED-----DVDVEEEEDEDEDD 267
E+ + E +DE EDD
Sbjct: 231 EEEGGKGEKRKRETDDEGEDD 251
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 61.6 bits (148), Expect = 4e-09
Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 17/174 (9%)
Query: 160 KHADGEKEDQFNGS----PPRPQP-------RGPRTPPGPPPPDDDEDDPVPLPVSGDKE 208
K D +++ + + S P + QP R P P PD E + + +
Sbjct: 107 KRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRS 166
Query: 209 EDAPHREDYFEPISPDR------NSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEED 262
+ E E D +S Q +E E EE EE EE E+D + +EE D
Sbjct: 167 SQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVD 226
Query: 263 EDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETF 316
ED ++ + EEEEE+EEEE E+DE + ++G + + E + E +F
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSF 280
Score = 40.0 bits (92), Expect = 0.013
Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 9/84 (10%)
Query: 235 SDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEG 294
S+E + E G DE + E EE+ E+D EE+EE EE+ EEDEE +
Sbjct: 176 SEEYGSDHETGSSGSSDEQGNNTENEEEGVEED-------VEEDEE-VEEDAEEDEEVD- 226
Query: 295 DDGYEQISSDEDGIADLERETFKY 318
+DG E+ +E+ + E E +Y
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEY 250
Score = 38.9 bits (89), Expect = 0.028
Identities = 36/127 (28%), Positives = 51/127 (40%), Gaps = 38/127 (29%)
Query: 192 DDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEED 251
D +ED+ V D+E D +GE EEE++EE EE+
Sbjct: 208 DVEEDEEVEEDAEEDEEVDE-------------------------DGEEEEEEEEEEEEE 242
Query: 252 EDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGD----DGYEQISSDEDG 307
E EEEE+E E D R +EE D + E + G DG + S DG
Sbjct: 243 E-----EEEEEEYEQDERD----QKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293
Query: 308 IADLERE 314
+ ++E
Sbjct: 294 SDEKKKE 300
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 60.8 bits (146), Expect = 7e-09
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 10/131 (7%)
Query: 163 DGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPIS 222
D E ED+ +P + P +D++D+ D +E+ E+ E
Sbjct: 159 DDEDEDE---DEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTP 215
Query: 223 PDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDE 282
+ + E+E +EE +EDEDD D E++ED+D++D EEEEE+E
Sbjct: 216 AKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDED-------DEEEEEEE 268
Query: 283 EEEGEEDEEGE 293
EEE ++ G+
Sbjct: 269 EEEPVKEAPGK 279
Score = 57.0 bits (136), Expect = 1e-07
Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 25/128 (19%)
Query: 192 DDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSV-PQEGQYSDEGEVEEEQQEEGEE 250
D++EDD D++ED ED EP + + P DE + ++E ++ EE
Sbjct: 146 DEEEDDDSEEDEEDDEDEDED--EDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEE 203
Query: 251 DEDDVD----------------------VEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEE 288
D+ + + V E+EDE+EDD D E++E+D++E+ EE
Sbjct: 204 DDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEE 263
Query: 289 DEEGEGDD 296
+EE E ++
Sbjct: 264 EEEEEEEE 271
Score = 53.9 bits (128), Expect = 9e-07
Identities = 39/142 (27%), Positives = 62/142 (43%), Gaps = 40/142 (28%)
Query: 201 LPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEE-----------GE 249
+P G K +ED E D +E + DE E E+E + E
Sbjct: 129 IPAKGAKNGKNAKKEDSDEEEDDDS----EEDEEDDEDEDEDEDEIEPAAMKAAAAAPAS 184
Query: 250 EDEDDVDVEEEEDEDEDD----------------RRTVDSIP---------EEEEEDEEE 284
EDEDD D E++ED+D+D+ ++ +P E+EEED+E+
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244
Query: 285 EGEEDEEGEGDDGYEQISSDED 306
E ++D+E + DD E +E+
Sbjct: 245 EDDDDDEDDEDDDDEDDEEEEE 266
Score = 51.2 bits (121), Expect = 6e-06
Identities = 27/80 (33%), Positives = 51/80 (63%), Gaps = 4/80 (5%)
Query: 230 QEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEE-EEDEEEEGEE 288
+ G+ + + + +EE+ ++ EEDE+D D +E+EDEDE + + + EDE++E +E
Sbjct: 135 KNGKNAKKEDSDEEEDDDSEEDEED-DEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193
Query: 289 DEEGEGDDGYEQISSDEDGI 308
D+E + DD E+ S+E+ +
Sbjct: 194 DDEDDDDD--EEDDSEEEAM 211
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/84 (33%), Positives = 48/84 (57%), Gaps = 12/84 (14%)
Query: 227 SVPQEGQYSDEGEVEEEQQEEGEEDEDD-VDVEEEEDEDEDD-------RRTVDSIPEEE 278
++P +G + + +E+ EE ED+D D E++EDEDED+ + + P E
Sbjct: 128 AIPAKGAKNGKNAKKEDSDEE--EDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASE 185
Query: 279 EEDEE--EEGEEDEEGEGDDGYEQ 300
+ED+E E+ E+D++ E DD E+
Sbjct: 186 DEDDEDDEDDEDDDDDEEDDSEEE 209
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 60.8 bits (146), Expect = 7e-09
Identities = 37/99 (37%), Positives = 55/99 (55%), Gaps = 9/99 (9%)
Query: 206 DKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDE---DDVDVEEEED 262
DKE E Y E + + +E +Y ++ +V E++++E EE+E +DV EEEED
Sbjct: 152 DKEAPDSDAEGYVEGLDDEEEDEDEE-EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
Query: 263 EDEDDRRTVDSIPEEEEEDEEEEG-----EEDEEGEGDD 296
E+ + VD +EEE EEE G E ++EGE DD
Sbjct: 211 EEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
Score = 56.2 bits (134), Expect = 2e-07
Identities = 29/67 (43%), Positives = 42/67 (62%), Gaps = 2/67 (2%)
Query: 241 EEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQ 300
EEE ++E E DED VE+EEDEDE++ + + EEEEDE EG D E + ++ E+
Sbjct: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDE--EGYNDGEVDDEEDEEE 227
Query: 301 ISSDEDG 307
+ +E G
Sbjct: 228 LGEEERG 234
Score = 52.8 bits (125), Expect = 2e-06
Identities = 30/82 (36%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Query: 231 EGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEED- 289
+G D+ E + E E DD + +E+E+E ++D + V+ +EE+EDEEEEGEE+
Sbjct: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVE---DEEDEDEEEEGEEED 202
Query: 290 ---EEGEGDDGYE--QISSDED 306
EE E ++GY ++ +ED
Sbjct: 203 VSGEEEEDEEGYNDGEVDDEED 224
Score = 52.8 bits (125), Expect = 2e-06
Identities = 33/80 (41%), Positives = 47/80 (58%), Gaps = 10/80 (12%)
Query: 237 EGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEE--GEEDEEGEG 294
EG VE EE +EDE++ D + + EDE+D +EEEE EEE+ GEE+E+ EG
Sbjct: 161 EGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDE-------DEEEEGEEEDVSGEEEEDEEG 213
Query: 295 -DDGYEQISSDEDGIADLER 313
+DG DE+ + + ER
Sbjct: 214 YNDGEVDDEEDEEELGEEER 233
Score = 47.4 bits (111), Expect = 8e-05
Identities = 31/92 (33%), Positives = 50/92 (54%), Gaps = 9/92 (9%)
Query: 224 DRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDV----EEEEDEDEDDRRTVDSIPEEEE 279
D+ + + + EG +EE+ E+ EE ++D V E+E++E+E + V EE+E
Sbjct: 152 DKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDE 211
Query: 280 E---DEEEEGEEDEE--GEGDDGYEQISSDED 306
E D E + EEDEE GE + G ++ ED
Sbjct: 212 EGYNDGEVDDEEDEEELGEEERGQKRKREPED 243
Score = 37.7 bits (86), Expect = 0.063
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 13/73 (17%)
Query: 253 DDVDVEEEEDEDEDDRRTVDSIPEEEE-EDE------------EEEGEEDEEGEGDDGYE 299
D D +++E D D V+ + +EEE EDE EE+ +E+EEGE +D
Sbjct: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205
Query: 300 QISSDEDGIADLE 312
+ DE+G D E
Sbjct: 206 EEEEDEEGYNDGE 218
Score = 31.6 bits (70), Expect = 4.5
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Query: 264 DEDDRRTVDSIPEEEEE--DEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
D DD+ DS E E D+EEE E++EE + D + DED + E E
Sbjct: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEE 201
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 60.5 bits (145), Expect = 9e-09
Identities = 59/238 (24%), Positives = 85/238 (35%), Gaps = 56/238 (23%)
Query: 137 DSPPPPPPPPPP----PQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPD 192
D P PPP P P P PS + SP P P P PP PP P
Sbjct: 181 DGGPAPPPAPSSASSSPSPSPS----------------SSSPSPPPPPPPPAPPAPPAPR 224
Query: 193 DDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDE 252
D DP P E Y P +P++ P E S+ E EE+E
Sbjct: 225 FDIYDPFH-----------PTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEE 273
Query: 253 DDVDVEEEEDEDEDD---------RRTVDSIPEEEEEDEEEEGEEDEEGEGDDGY----- 298
++ + EEEEDE+E++ T+ I ++ ++ G+E +
Sbjct: 274 EEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAP 333
Query: 299 ----EQISSDEDG-------IADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDREL 345
+ S+ DG + E E + VE A++PP P D E+
Sbjct: 334 GTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEI 391
Score = 33.5 bits (75), Expect = 1.2
Identities = 29/136 (21%), Positives = 52/136 (38%), Gaps = 22/136 (16%)
Query: 164 GEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISP 223
G +E ++G + R + P PPP + P P ++ D + +
Sbjct: 958 GAEETSWSG-----EERAAKVPSTPPP----KAAPPPPALTPDSQ-------------TV 995
Query: 224 DRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEE 283
D + E + E EE G E+E++ + EEEE+E+E++++ +
Sbjct: 996 DSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAP 1055
Query: 284 EEGEEDEEGEGDDGYE 299
GD G E
Sbjct: 1056 STAPSAGSTAGDSGAE 1071
Score = 33.5 bits (75), Expect = 1.2
Identities = 27/112 (24%), Positives = 44/112 (39%), Gaps = 12/112 (10%)
Query: 186 PGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQ 245
P PPP P P S + +P+ + +P+E ++E V +
Sbjct: 974 PSTPPPKAAPPPPALTPDSQTVDSSCK---------TPEVSFLPEEA--TEEAGVRGGAE 1022
Query: 246 EEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDG 297
EE EE+E++ + EEEE+E + T S G + +DG
Sbjct: 1023 EE-EEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDG 1073
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 59.7 bits (143), Expect = 2e-08
Identities = 38/108 (35%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 214 REDYFEPISPDRNSV-------PQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDED 266
R Y E IS R S+ P+ + + + + E E+ +E +ED++D D EEE+DE+ D
Sbjct: 605 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD 664
Query: 267 DRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
E EDE E+G+E+EE DD E D+D D E E
Sbjct: 665 SSEDGGDSSESSSEDESEDGDENEE---DDEDEDDDEDDDEDEDNESE 709
Score = 51.6 bits (122), Expect = 4e-06
Identities = 39/133 (29%), Positives = 56/133 (42%), Gaps = 35/133 (26%)
Query: 177 PQPRGPRTP---PGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQ 233
P P+ RT DD+ED+ D++ED +D + ++G
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDED-------DEDEDEEEEDD-------ENGDSSEDGG 670
Query: 234 YSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGE 293
S E E+E ++ E +EDD E+ED+DEDD +E+ED E EG
Sbjct: 671 DSSESSSEDESEDGDENEEDD----EDEDDDEDD---------DEDEDNESEGSSSSSSS 717
Query: 294 GDDGYEQISSDED 306
D SSD D
Sbjct: 718 SGD-----SSDSD 725
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 59.7 bits (143), Expect = 2e-08
Identities = 38/108 (35%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 214 REDYFEPISPDRNSV-------PQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDED 266
R Y E IS R S+ P+ + + + + E E+ +E +ED++D D EEE+DE+ D
Sbjct: 605 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD 664
Query: 267 DRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
E EDE E+G+E+EE DD E D+D D E E
Sbjct: 665 SSEDGGDSSESSSEDESEDGDENEE---DDEDEDDDEDDDEDEDNESE 709
Score = 51.6 bits (122), Expect = 4e-06
Identities = 39/133 (29%), Positives = 56/133 (42%), Gaps = 35/133 (26%)
Query: 177 PQPRGPRTP---PGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQ 233
P P+ RT DD+ED+ D++ED +D + ++G
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDED-------DEDEDEEEEDD-------ENGDSSEDGG 670
Query: 234 YSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGE 293
S E E+E ++ E +EDD E+ED+DEDD +E+ED E EG
Sbjct: 671 DSSESSSEDESEDGDENEEDD----EDEDDDEDD---------DEDEDNESEGSSSSSSS 717
Query: 294 GDDGYEQISSDED 306
D SSD D
Sbjct: 718 SGD-----SSDSD 725
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 59.7 bits (143), Expect = 2e-08
Identities = 38/108 (35%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 214 REDYFEPISPDRNSV-------PQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDED 266
R Y E IS R S+ P+ + + + + E E+ +E +ED++D D EEE+DE+ D
Sbjct: 642 RAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGD 701
Query: 267 DRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
E EDE E+G+E+EE DD E D+D D E E
Sbjct: 702 SSEDGGDSSESSSEDESEDGDENEE---DDEDEDDDEDDDEDEDNESE 746
Score = 51.6 bits (122), Expect = 4e-06
Identities = 39/133 (29%), Positives = 56/133 (42%), Gaps = 35/133 (26%)
Query: 177 PQPRGPRTP---PGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQ 233
P P+ RT DD+ED+ D++ED +D + ++G
Sbjct: 662 PNPKSSRTTLQSKSESEEDDEEDED-------DEDEDEEEEDD-------ENGDSSEDGG 707
Query: 234 YSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGE 293
S E E+E ++ E +EDD E+ED+DEDD +E+ED E EG
Sbjct: 708 DSSESSSEDESEDGDENEEDD----EDEDDDEDD---------DEDEDNESEGSSSSSSS 754
Query: 294 GDDGYEQISSDED 306
D SSD D
Sbjct: 755 SGD-----SSDSD 762
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 59.3 bits (142), Expect = 2e-08
Identities = 60/258 (23%), Positives = 93/258 (36%), Gaps = 38/258 (14%)
Query: 127 SVDRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPP 186
S+ + D PP P PP Q + + G S PRP+ R P
Sbjct: 599 SMQALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRR-ESDPT 657
Query: 187 GPP-------PPDDDEDDPVPLPVSGDKEEDAPHREDYFE-------------------- 219
GP PP + P +P+S ++ DY E
Sbjct: 658 GPQRQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTT 717
Query: 220 ------PISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDS 273
P+ P N +E + ++ E EEE +EE EE+E++ + EEEE+E+E++ +
Sbjct: 718 PQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVA 777
Query: 274 IPE--EEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLA 331
+ E EG E +G +D R + + + E ++ L
Sbjct: 778 LGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLV 837
Query: 332 SVPP--MTYDPYDRELVP 347
V P M P EL P
Sbjct: 838 LVSPGDMKKSPVTAELAP 855
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 58.5 bits (140), Expect = 3e-08
Identities = 53/197 (26%), Positives = 81/197 (41%), Gaps = 36/197 (18%)
Query: 135 DRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKED------------------------QF 170
+ + P P P P P +K + K G +ED +
Sbjct: 713 EEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEK 772
Query: 171 NGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQ 230
+G +P+ G G +DE++ + ++E H ED E + + Q
Sbjct: 773 SGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDG-EMKGNEGETESQ 831
Query: 231 EGQYSDEGEVEEEQQEEGEED---EDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGE 287
E + GE + + E+G ED D D EEEE+E+E+ EEEEE++EEE E
Sbjct: 832 ELSAENHGEAKND--EKGVEDGGGSDGGDSEEEEEEEEEQEE------EEEEEEQEEEEE 883
Query: 288 EDEEGEGDDGYEQISSD 304
E+EE E E +S D
Sbjct: 884 EEEEEEEKGNEEPLSLD 900
Score = 30.8 bits (68), Expect = 7.7
Identities = 16/45 (35%), Positives = 26/45 (57%)
Query: 230 QEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSI 274
+E Q +E E E+E++EE EE+E++ EE D + R +I
Sbjct: 866 EEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAI 910
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 58.2 bits (139), Expect = 5e-08
Identities = 45/148 (30%), Positives = 66/148 (44%), Gaps = 12/148 (8%)
Query: 139 PPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDP 198
P P P P P P P E + +P P P+ PPP + +P
Sbjct: 10036 PKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPV-PKKVEAPPPKVPKKREP 10094
Query: 199 VPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVE 258
VP+PV+ +EE+ E+ VP+E +E EV E++E E+E+ + E
Sbjct: 10095 VPVPVALPQEEEVLFEEEI----------VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEE 10144
Query: 259 EE-EDEDEDDRRTVDSIPEEEEEDEEEE 285
EE E+E+ + +PEEEE EEE
Sbjct: 10145 EEIPPEEEEVPPEEEYVPEEEEFVPEEE 10172
Score = 54.7 bits (130), Expect = 5e-07
Identities = 51/181 (28%), Positives = 75/181 (41%), Gaps = 25/181 (13%)
Query: 131 VISHDRDSPPPPPPPPPPPQPQPSLKRN---PKHADGE--------KEDQFNGSPPRPQP 179
V+ ++ PPP P P +P P K PK + K+ P P P
Sbjct: 9991 VLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAP 10050
Query: 180 RGPRTPPGPPP-------PDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEG 232
+ PP P P++ + PVP V + RE P++ +PQE
Sbjct: 10051 KKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVA-----LPQEE 10105
Query: 233 QYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEE--DEEEEGEEDE 290
+ E E+ E++ EE+E + EE E+E+ + IP EEEE EEE E+E
Sbjct: 10106 EVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEE 10165
Query: 291 E 291
E
Sbjct: 10166 E 10166
Score = 52.0 bits (123), Expect = 3e-06
Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 29/180 (16%)
Query: 131 VISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPP 190
+++ +SPPP P P + K P+ KE++ P P+ P P
Sbjct: 9387 IVTQREESPPPAVPEIPKKKVPEERKPVPR-----KEEEV--------PPPPKVPALPKK 9433
Query: 191 PDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEE 250
P +E VP+PV+ K+ P E + +V +E ++ E ++ + E
Sbjct: 9434 PVPEEKVAVPVPVA--KKAPPPRAE-------VSKKTVVEEKRFVAEEKLSFAVPQRVEV 9484
Query: 251 DEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIAD 310
+V EEE E++ S+ EEE +EEEE E E YE + E+ + +
Sbjct: 9485 TRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTE-------YEVMEEPEEYVVE 9537
Score = 44.3 bits (103), Expect = 7e-04
Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 28/199 (14%)
Query: 136 RDSPPPPPPPPPPPQPQPSLKRNPK---------------HADGEKEDQFNGSPPRPQ-P 179
++ PPP P P +P P K PK H +E++ + + + P
Sbjct: 9600 KEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAP 9659
Query: 180 RGPRTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEP--ISPDRNSVP---QEGQY 234
R P P +E L + +EE+ P + F + ++ S+ +E Q
Sbjct: 9660 PKARVPEEPKRAVPEEK---VLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQP 9716
Query: 235 SDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEG 294
E + EE++ +E+ V V+ EE+ +E + E E +E ++ EE EE E
Sbjct: 9717 IKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEERE- 9775
Query: 295 DDGYEQISSDEDGIADLER 313
YE+ E+ I + E+
Sbjct: 9776 ---YERYEEHEEYITEPEK 9791
Score = 40.8 bits (94), Expect = 0.007
Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 16/129 (12%)
Query: 141 PPPPPPPPPQPQPSL------KRNPKHADGEKEDQFNGSPPRPQPRGPRTPPG-----PP 189
P P PPPP+P + KR K + K + + P P P P P
Sbjct: 10975 PAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKP 11034
Query: 190 PPDDDEDD----PVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQ 245
PP + E PV +PV G K E +E+ +P P + VP++ E E + +
Sbjct: 11035 PPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIK-GVPKKTPSPIEAERRKLRP 11093
Query: 246 EEGEEDEDD 254
G E D
Sbjct: 11094 GSGGEKPPD 11102
Score = 40.0 bits (92), Expect = 0.013
Identities = 39/163 (23%), Positives = 65/163 (39%), Gaps = 24/163 (14%)
Query: 132 ISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPR---------GP 182
I+ + + P P P P P++ PK EK+ P P P+ P
Sbjct: 10816 IAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKP 10875
Query: 183 RTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEE 242
+ P PPPP P P +ED +E F+ + + VP++ Q ++ E+
Sbjct: 10876 KLKPRPPPP-----PPAP------PKEDV--KEKIFQLKAIPKKKVPEKPQVPEKVELTP 10922
Query: 243 EQQEEGEEDEDDVDVEEEEDEDEDD--RRTVDSIPEEEEEDEE 283
+ GE+ + E + + E+ + + PEEEE E
Sbjct: 10923 LKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE 10965
Score = 39.3 bits (90), Expect = 0.022
Identities = 48/196 (24%), Positives = 75/196 (38%), Gaps = 41/196 (20%)
Query: 139 PPPPPPPPPPPQPQPSLKRNP-------KHADGEKEDQFNGSPPRPQPRGPRTPPGPPPP 191
PP PP P P P K+ P K A + + P PR PPP
Sbjct: 8958 PPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPT 9017
Query: 192 DDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQ---EGQYSDEGEVEEEQQ--- 245
+P + D + + + ++ R Q E Y + V +E++
Sbjct: 9018 -------TLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFI 9070
Query: 246 EEGEEDEDDVDVE-----------EEEDEDEDDRRTV--DSIPEEEEED--------EEE 284
E EE D+++VE EE DED ++ + + EE EED E E
Sbjct: 9071 ESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYERE 9130
Query: 285 EGEEDEEGEGDDGYEQ 300
EG ++ E E ++ Y++
Sbjct: 9131 EGYDEGEEEWEEAYQE 9146
Score = 37.7 bits (86), Expect = 0.063
Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 31/133 (23%)
Query: 129 DRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGP 188
++VI + P PPPPPP P PK EK Q P + P P+ P
Sbjct: 10869 EKVIEKPKLKPRPPPPPPAP----------PKEDVKEKIFQLKAIPKKKVPEKPQVP--- 10915
Query: 189 PPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEG 248
++ + PL V G +++ + P+R P+E E ++ ++
Sbjct: 10916 -----EKVELTPLKVPGGEKK--------VRKLLPERKPEPKE-----EVVLKSVLRKRP 10957
Query: 249 EEDEDDVDVEEEE 261
EE+E V+ ++ E
Sbjct: 10958 EEEEPKVEPKKLE 10970
Score = 36.2 bits (82), Expect = 0.18
Identities = 43/164 (26%), Positives = 63/164 (38%), Gaps = 27/164 (16%)
Query: 131 VISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGP-- 188
V+ + PPP P PP P + PK A EK+ PP+P+ P P P
Sbjct: 10532 VVPEKKVPVPPPKKPEVPPTKVPEV---PKAAVPEKKVP-EAIPPKPESPPPEVPEAPKE 10587
Query: 189 ---------PPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDR------NSVPQEGQ 233
PP E PV +P + +E P ++ P+ P + VP+ +
Sbjct: 10588 VVPEKKVPAAPPKKPEVTPVKVPEA--PKEVVPEKK---VPVPPPKKPEVPPTKVPEVPK 10642
Query: 234 YS-DEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPE 276
+ E +V E + E +V E EE E+ V PE
Sbjct: 10643 VAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPE 10686
Score = 34.7 bits (78), Expect = 0.53
Identities = 39/167 (23%), Positives = 59/167 (35%), Gaps = 22/167 (13%)
Query: 141 PPPPPPPPPQPQPSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDP-- 198
P PP P P P + PK EK+ P P P+ P PP P P
Sbjct: 10511 PVPPAKKPEAPPPKVPEAPKEVVPEKK------VPVPPPKKPEVPPTKVPEVPKAAVPEK 10564
Query: 199 -VPLPVSGDKEEDAPHREDYFEPISPDRN--SVPQEGQYSDEGEVEEEQQEEGEEDEDDV 255
VP + E P + + + P++ + P + +V E +E E + V
Sbjct: 10565 KVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPV 10624
Query: 256 -----------DVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEE 291
V E +++ ++IP + E E EE EE
Sbjct: 10625 PPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEE 10671
Score = 33.9 bits (76), Expect = 0.91
Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 17/102 (16%)
Query: 182 PRTPPGPPP----PDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDE 237
P T P P PD+D ++ + V KE ED+ E QE +E
Sbjct: 9084 PYTEPFEQPYYEEPDEDYEE---IKVEAKKEVHEEWEEDFEEG---------QEYYEREE 9131
Query: 238 GEVE-EEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEE 278
G E EE+ EE ++ + + V++E E+ +R+ +PE++
Sbjct: 9132 GYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKK 9173
Score = 33.9 bits (76), Expect = 0.91
Identities = 45/164 (27%), Positives = 62/164 (37%), Gaps = 30/164 (18%)
Query: 137 DSPPPPPPPP---PPPQPQPSLK------RNP-----KHADGEKEDQFNGSPPRPQPRGP 182
+ P P PP PP +P P K + P K + KE P P+ P
Sbjct: 10683 EEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKP 10742
Query: 183 RTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHR--EDYFEPISPDRNSVP-QEGQYSDEGE 239
PP P E P K E P + E +P+ ++ +VP E S E
Sbjct: 10743 EAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPE 10802
Query: 240 VEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEE 283
V EE +E E+E + EEE+ +P EEE+ E
Sbjct: 10803 VYEEPEEIAPEEE--IAPEEEKP-----------VPVAEEEEPE 10833
Score = 32.7 bits (73), Expect = 2.0
Identities = 40/146 (27%), Positives = 64/146 (43%), Gaps = 19/146 (13%)
Query: 175 PRPQPRGPRTPPGPPPPDDDEDDPVPLPVSGD-----KEEDAPHREDYFEPISPDRNSVP 229
P P P+ PP E+ VP+PV K + P + + + P + +VP
Sbjct: 10281 PTPVPKKVEAPPAKVSKKIPEEK-VPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVP 10339
Query: 230 Q-EGQYSDEGEVEEE-QQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGE 287
+G+ E +V +QE ++ +++V E E V+ IPEEEE E E E
Sbjct: 10340 PAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAE---------VEEIPEEEEFHEVE--E 10388
Query: 288 EDEEGEGDDGYEQISSDEDGIADLER 313
EEGE + E I ++ + + R
Sbjct: 10389 YFEEGEFHEVEEFIKLEQHRVEEEHR 10414
Score = 32.0 bits (71), Expect = 3.5
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 2/75 (2%)
Query: 212 PHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGE--EDEDDVDVEEEEDEDEDDRR 269
P + Y+E D + E + E EE+ +E E E E+ D EEE E+ R
Sbjct: 9088 PFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQER 9147
Query: 270 TVDSIPEEEEEDEEE 284
V + +E E+ E
Sbjct: 9148 EVIQVQKEVYEESHE 9162
Score = 32.0 bits (71), Expect = 3.5
Identities = 43/168 (25%), Positives = 66/168 (39%), Gaps = 8/168 (4%)
Query: 129 DRVISHDRDSPPPPPPPPPPPQPQPSLKRNPKHADGE--KEDQFNGSPPRPQPRGPRTPP 186
+R H+ P P P P P+ + PK + K+ P P P+ + PP
Sbjct: 9777 ERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPP 9836
Query: 187 GPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFE-PISPDRNSVPQEGQYSDEGEVEEEQQ 245
P + + + +S K E E + P+ P R V +E EV +
Sbjct: 9837 PKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKR-VVAEEKVPVPRKEVAPPVR 9895
Query: 246 EEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEE--DEEEEGEEDEE 291
E +++ EE E+E + + EEEEE EEEE +EE
Sbjct: 9896 VP--EVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEE 9941
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 58.2 bits (139), Expect = 5e-08
Identities = 37/115 (32%), Positives = 65/115 (56%), Gaps = 6/115 (5%)
Query: 215 EDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSI 274
EDY E I + Q+ Y D + E+ + + EE++D+ E++E+E+E++ +
Sbjct: 129 EDYRESIF----ELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGY 184
Query: 275 PEEEEEDEEEEGEEDEEGEGDDGYEQISSDED-GIADLERETFKYPNFDVEYTAE 328
EEEEE+EEE+ +EDE+ E + G E +E+ G++ L +E + D +Y E
Sbjct: 185 EEEEEEEEEEDEDEDED-EDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEE 238
Score = 57.8 bits (138), Expect = 6e-08
Identities = 42/124 (33%), Positives = 59/124 (47%), Gaps = 22/124 (17%)
Query: 193 DDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDE 252
D ED+ P D EE+ D + + + P EG Y +E E EEE+ E+ +EDE
Sbjct: 149 DQEDNEAP-----DSEEEDDEDGDEDDEEEEENEAGPPEG-YEEEEEEEEEEDEDEDEDE 202
Query: 253 DDVDVEEEEDEDE------------DDRRTVDSIPEEEEEDEEEE----GEEDEEGEGDD 296
D+ E E E+E D+ D + E EEE+EEEE GE+ + DD
Sbjct: 203 DEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 262
Query: 297 GYEQ 300
G E+
Sbjct: 263 GEEE 266
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 17/114 (14%)
Query: 217 YFEPISPDRNSVP----QEGQYSDEGEVEEEQQEEG-----EEDEDDVDVEEEEDEDEDD 267
Y + + N P ++ + DE + EEE+ E G EE+E++ + E+E++++++D
Sbjct: 144 YLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED 203
Query: 268 RRTVDSIPEEEEE-------DEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
+ E EEE EE + EED++ ++G E+ +E G+ +R+
Sbjct: 204 -EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 256
Score = 46.2 bits (108), Expect = 2e-04
Identities = 36/112 (32%), Positives = 57/112 (50%), Gaps = 20/112 (17%)
Query: 192 DDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDE-----GEVEEE--- 243
D DEDD ++E +A E Y E + E + DE GE EEE
Sbjct: 165 DGDEDD------EEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGL 218
Query: 244 ---QQEEGEEDEDDVD-VEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEE 291
+EE +++EDD D VEE E+E+E++ + E+ + D E++GEE+++
Sbjct: 219 SYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRG--EKRKRDAEDDGEEEDD 268
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 58.2 bits (139), Expect = 5e-08
Identities = 37/115 (32%), Positives = 65/115 (56%), Gaps = 6/115 (5%)
Query: 215 EDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSI 274
EDY E I + Q+ Y D + E+ + + EE++D+ E++E+E+E++ +
Sbjct: 88 EDYRESIF----ELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGY 143
Query: 275 PEEEEEDEEEEGEEDEEGEGDDGYEQISSDED-GIADLERETFKYPNFDVEYTAE 328
EEEEE+EEE+ +EDE+ E + G E +E+ G++ L +E + D +Y E
Sbjct: 144 EEEEEEEEEEDEDEDED-EDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEE 197
Score = 57.8 bits (138), Expect = 6e-08
Identities = 42/124 (33%), Positives = 59/124 (47%), Gaps = 22/124 (17%)
Query: 193 DDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDE 252
D ED+ P D EE+ D + + + P EG Y +E E EEE+ E+ +EDE
Sbjct: 108 DQEDNEAP-----DSEEEDDEDGDEDDEEEEENEAGPPEG-YEEEEEEEEEEDEDEDEDE 161
Query: 253 DDVDVEEEEDEDE------------DDRRTVDSIPEEEEEDEEEE----GEEDEEGEGDD 296
D+ E E E+E D+ D + E EEE+EEEE GE+ + DD
Sbjct: 162 DEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 221
Query: 297 GYEQ 300
G E+
Sbjct: 222 GEEE 225
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 17/114 (14%)
Query: 217 YFEPISPDRNSVP----QEGQYSDEGEVEEEQQEEG-----EEDEDDVDVEEEEDEDEDD 267
Y + + N P ++ + DE + EEE+ E G EE+E++ + E+E++++++D
Sbjct: 103 YLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED 162
Query: 268 RRTVDSIPEEEEE-------DEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
+ E EEE EE + EED++ ++G E+ +E G+ +R+
Sbjct: 163 -EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 215
Score = 46.2 bits (108), Expect = 2e-04
Identities = 36/112 (32%), Positives = 57/112 (50%), Gaps = 20/112 (17%)
Query: 192 DDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDE-----GEVEEE--- 243
D DEDD ++E +A E Y E + E + DE GE EEE
Sbjct: 124 DGDEDD------EEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGL 177
Query: 244 ---QQEEGEEDEDDVD-VEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEE 291
+EE +++EDD D VEE E+E+E++ + E+ + D E++GEE+++
Sbjct: 178 SYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRG--EKRKRDAEDDGEEEDD 227
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 58.2 bits (139), Expect = 5e-08
Identities = 37/115 (32%), Positives = 65/115 (56%), Gaps = 6/115 (5%)
Query: 215 EDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSI 274
EDY E I + Q+ Y D + E+ + + EE++D+ E++E+E+E++ +
Sbjct: 81 EDYRESIF----ELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGY 136
Query: 275 PEEEEEDEEEEGEEDEEGEGDDGYEQISSDED-GIADLERETFKYPNFDVEYTAE 328
EEEEE+EEE+ +EDE+ E + G E +E+ G++ L +E + D +Y E
Sbjct: 137 EEEEEEEEEEDEDEDED-EDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEE 190
Score = 57.8 bits (138), Expect = 6e-08
Identities = 42/124 (33%), Positives = 59/124 (47%), Gaps = 22/124 (17%)
Query: 193 DDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDE 252
D ED+ P D EE+ D + + + P EG Y +E E EEE+ E+ +EDE
Sbjct: 101 DQEDNEAP-----DSEEEDDEDGDEDDEEEEENEAGPPEG-YEEEEEEEEEEDEDEDEDE 154
Query: 253 DDVDVEEEEDEDE------------DDRRTVDSIPEEEEEDEEEE----GEEDEEGEGDD 296
D+ E E E+E D+ D + E EEE+EEEE GE+ + DD
Sbjct: 155 DEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDD 214
Query: 297 GYEQ 300
G E+
Sbjct: 215 GEEE 218
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 17/114 (14%)
Query: 217 YFEPISPDRNSVP----QEGQYSDEGEVEEEQQEEG-----EEDEDDVDVEEEEDEDEDD 267
Y + + N P ++ + DE + EEE+ E G EE+E++ + E+E++++++D
Sbjct: 96 YLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDED 155
Query: 268 RRTVDSIPEEEEE-------DEEEEGEEDEEGEGDDGYEQISSDEDGIADLERE 314
+ E EEE EE + EED++ ++G E+ +E G+ +R+
Sbjct: 156 -EAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK 208
Score = 46.2 bits (108), Expect = 2e-04
Identities = 36/112 (32%), Positives = 57/112 (50%), Gaps = 20/112 (17%)
Query: 192 DDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDE-----GEVEEE--- 243
D DEDD ++E +A E Y E + E + DE GE EEE
Sbjct: 117 DGDEDD------EEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGL 170
Query: 244 ---QQEEGEEDEDDVD-VEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEE 291
+EE +++EDD D VEE E+E+E++ + E+ + D E++GEE+++
Sbjct: 171 SYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRG--EKRKRDAEDDGEEEDD 220
>gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein
[Homo sapiens]
Length = 593
Score = 57.8 bits (138), Expect = 6e-08
Identities = 49/164 (29%), Positives = 71/164 (43%), Gaps = 26/164 (15%)
Query: 136 RDSPPPPPPPPPPPQPQ--PSLKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDD 193
R PP PP PP + + P R P+ A ++ + R G P P
Sbjct: 24 RQQLPPDPPAAPPGRARAAPDEDREPESARMQRAQMAALAAMRAAAAGLGHPASP---GG 80
Query: 194 DEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDED 253
ED P G +EEDA P SP R ++ ++ +E+ + + EE+E
Sbjct: 81 SEDGP-----PGSEEEDAAREGT---PGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEM 132
Query: 254 DVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDG 297
+ D+ E+E+E EEE+ E+EE EEDEEG G G
Sbjct: 133 EEDLGEDEEE-------------EEEDYEDEEEEEDEEGLGPPG 163
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 57.4 bits (137), Expect = 8e-08
Identities = 43/169 (25%), Positives = 76/169 (44%), Gaps = 10/169 (5%)
Query: 183 RTPPGPPPPDDDEDDPVPLPVSGDKEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEE 242
R+PP PP + D PV +K E+ D + +R + E ++ G E
Sbjct: 221 RSPPRPPRERFELGDGRK-PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 279
Query: 243 EQQEEGEEDEDD----VDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGY 298
E++EE EE+E++ + EEEE+E+E++ S EE E EE E+E E ++
Sbjct: 280 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE-- 337
Query: 299 EQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTYDPYDRELVP 347
+E+ + + F + + E E++ P + + + VP
Sbjct: 338 ---RENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVP 383
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,232,617
Number of Sequences: 37866
Number of extensions: 3044922
Number of successful extensions: 88906
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1126
Number of HSP's successfully gapped in prelim test: 1177
Number of HSP's that attempted gapping in prelim test: 26650
Number of HSP's gapped (non-prelim): 26793
length of query: 1147
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1034
effective length of database: 13,968,660
effective search space: 14443594440
effective search space used: 14443594440
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.