Search of human proteins with 33286418

Search of human proteins with 33286418

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33286418 pyruvate kinase, muscle isoform M2 [Homo sapiens]
         (531 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33286418 pyruvate kinase, muscle isoform M2 [Homo sapiens]        1050   0.0  
gi|33286422 pyruvate kinase, muscle isoform M1 [Homo sapiens]        1007   0.0  
gi|33286420 pyruvate kinase, muscle isoform M1 [Homo sapiens]        1007   0.0  
gi|32967597 pyruvate kinase, liver and RBC isoform 2 [Homo sapiens]   764   0.0  
gi|10835121 pyruvate kinase, liver and RBC isoform 1 [Homo sapiens]   764   0.0  
gi|169218111 PREDICTED: similar to pyruvate kinase, muscle [Homo...   645   0.0  
gi|148235600 nucleolar protein 4 [Homo sapiens]                        34   0.29 
gi|27545315 translational activator of mitochondrially encoded c...    32   1.9  
gi|189458819 transferrin receptor [Homo sapiens]                       31   3.2  
gi|189458817 transferrin receptor [Homo sapiens]                       31   3.2  
gi|32483410 vitamin D-binding protein precursor [Homo sapiens]         29   9.4  
gi|18079254 p53 and DNA damage-regulated protein [Homo sapiens]        29   9.4  

>gi|33286418 pyruvate kinase, muscle isoform M2 [Homo sapiens]
          Length = 531

 Score = 1050 bits (2715), Expect = 0.0
 Identities = 531/531 (100%), Positives = 531/531 (100%)

Query: 1   MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET 60
           MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
Sbjct: 1   MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET 60

Query: 61  LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR 120
           LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
Sbjct: 61  LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR 120

Query: 121 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL 180
           TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
Sbjct: 121 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL 180

Query: 181 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
           ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
Sbjct: 181 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240

Query: 241 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE 300
           FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
Sbjct: 241 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE 300

Query: 301 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 360
           IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
Sbjct: 301 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 360

Query: 361 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS 420
           LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS
Sbjct: 361 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS 420

Query: 421 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE 480
           FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
Sbjct: 421 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE 480

Query: 481 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531
           AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
Sbjct: 481 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531


>gi|33286422 pyruvate kinase, muscle isoform M1 [Homo sapiens]
          Length = 531

 Score = 1007 bits (2604), Expect = 0.0
 Identities = 509/531 (95%), Positives = 521/531 (98%)

Query: 1   MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET 60
           MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
Sbjct: 1   MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET 60

Query: 61  LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR 120
           LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
Sbjct: 61  LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR 120

Query: 121 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL 180
           TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
Sbjct: 121 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL 180

Query: 181 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
           ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
Sbjct: 181 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240

Query: 241 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE 300
           FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
Sbjct: 241 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE 300

Query: 301 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 360
           IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
Sbjct: 301 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 360

Query: 361 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS 420
           LSGETAKGDYPLEAVRMQHLIAREAEAA++H +LFEEL R +  ++D  EA A+G+VEAS
Sbjct: 361 LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEAS 420

Query: 421 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE 480
           +KC + A+IVLT+SGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
Sbjct: 421 YKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE 480

Query: 481 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531
           AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
Sbjct: 481 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531


>gi|33286420 pyruvate kinase, muscle isoform M1 [Homo sapiens]
          Length = 531

 Score = 1007 bits (2604), Expect = 0.0
 Identities = 509/531 (95%), Positives = 521/531 (98%)

Query: 1   MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET 60
           MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
Sbjct: 1   MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET 60

Query: 61  LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR 120
           LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
Sbjct: 61  LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR 120

Query: 121 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL 180
           TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
Sbjct: 121 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL 180

Query: 181 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
           ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
Sbjct: 181 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240

Query: 241 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE 300
           FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE
Sbjct: 241 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE 300

Query: 301 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 360
           IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM
Sbjct: 301 IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM 360

Query: 361 LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEAS 420
           LSGETAKGDYPLEAVRMQHLIAREAEAA++H +LFEEL R +  ++D  EA A+G+VEAS
Sbjct: 361 LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRASSHSTDLMEAMAMGSVEAS 420

Query: 421 FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE 480
           +KC + A+IVLT+SGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE
Sbjct: 421 YKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQE 480

Query: 481 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531
           AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP
Sbjct: 481 AWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP 531


>gi|32967597 pyruvate kinase, liver and RBC isoform 2 [Homo sapiens]
          Length = 543

 Score =  764 bits (1973), Expect = 0.0
 Identities = 376/524 (71%), Positives = 444/524 (84%)

Query: 7   EAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIK 66
           E GTAF Q QQL AAMADTFLEH+C LDIDS P+ AR+T II TIGPASRSVE LKEMIK
Sbjct: 19  ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIK 78

Query: 67  SGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKG 126
           +GMN+ARLNFSHG+HEYHAE+I NVR A ESFA  P+ YRPVA+ALDTKGPEIRTG+++G
Sbjct: 79  AGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQG 138

Query: 127 SGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVK 186
              +EVEL KG+ + +T+D A+  + + N +W+DY NI +VV VG +IY+DDGLISL V+
Sbjct: 139 GPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQ 198

Query: 187 QKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIR 246
           + G + LVT+VENGG LGS+KGVNLPGA VDLP +SE+D++DL+FGVE  VD+VFASF+R
Sbjct: 199 KIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVR 258

Query: 247 KASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKV 306
           KASDV  VR  LG +G  IKIISKIENHEGV+RFDEILE SDGIMVARGDLGIEIPAEKV
Sbjct: 259 KASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKV 318

Query: 307 FLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETA 366
           FLAQKMMIGRCN AGKPV+CATQMLESMI KPRPTRAE SDVANAVLDGADCIMLSGETA
Sbjct: 319 FLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETA 378

Query: 367 KGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSG 426
           KG++P+EAV+MQH IAREAEAA+YH QLFEELRR AP++ DPTE TA+GAVEA+FKCC+ 
Sbjct: 379 KGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAA 438

Query: 427 AIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDV 486
           AIIVLT +GRSA  ++RYRPRA +IAVTR+ Q ARQ HL RG+FP+L ++P +  WA+DV
Sbjct: 439 AIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDV 498

Query: 487 DLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
           D RV F +  GK RGF + GD+VIV+TGWRPGSG+TN MRV+ +
Sbjct: 499 DRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 542


>gi|10835121 pyruvate kinase, liver and RBC isoform 1 [Homo sapiens]
          Length = 574

 Score =  764 bits (1973), Expect = 0.0
 Identities = 376/524 (71%), Positives = 444/524 (84%)

Query: 7   EAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIK 66
           E GTAF Q QQL AAMADTFLEH+C LDIDS P+ AR+T II TIGPASRSVE LKEMIK
Sbjct: 50  ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIK 109

Query: 67  SGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKG 126
           +GMN+ARLNFSHG+HEYHAE+I NVR A ESFA  P+ YRPVA+ALDTKGPEIRTG+++G
Sbjct: 110 AGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQG 169

Query: 127 SGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVK 186
              +EVEL KG+ + +T+D A+  + + N +W+DY NI +VV VG +IY+DDGLISL V+
Sbjct: 170 GPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQ 229

Query: 187 QKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIR 246
           + G + LVT+VENGG LGS+KGVNLPGA VDLP +SE+D++DL+FGVE  VD+VFASF+R
Sbjct: 230 KIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVR 289

Query: 247 KASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKV 306
           KASDV  VR  LG +G  IKIISKIENHEGV+RFDEILE SDGIMVARGDLGIEIPAEKV
Sbjct: 290 KASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKV 349

Query: 307 FLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETA 366
           FLAQKMMIGRCN AGKPV+CATQMLESMI KPRPTRAE SDVANAVLDGADCIMLSGETA
Sbjct: 350 FLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETA 409

Query: 367 KGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSG 426
           KG++P+EAV+MQH IAREAEAA+YH QLFEELRR AP++ DPTE TA+GAVEA+FKCC+ 
Sbjct: 410 KGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAA 469

Query: 427 AIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDV 486
           AIIVLT +GRSA  ++RYRPRA +IAVTR+ Q ARQ HL RG+FP+L ++P +  WA+DV
Sbjct: 470 AIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDV 529

Query: 487 DLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 530
           D RV F +  GK RGF + GD+VIV+TGWRPGSG+TN MRV+ +
Sbjct: 530 DRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 573


>gi|169218111 PREDICTED: similar to pyruvate kinase, muscle [Homo
           sapiens]
          Length = 364

 Score =  645 bits (1663), Expect = 0.0
 Identities = 329/330 (99%), Positives = 329/330 (99%), Gaps = 1/330 (0%)

Query: 1   MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET 60
           MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET
Sbjct: 1   MSKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVET 60

Query: 61  LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR 120
           LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR
Sbjct: 61  LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIR 120

Query: 121 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL 180
           TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL
Sbjct: 121 TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL 180

Query: 181 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240
           ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV
Sbjct: 181 ISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV 240

Query: 241 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRR-FDEILEASDGIMVARGDLGI 299
           FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRR FDEILEASDGIMVARGDLGI
Sbjct: 241 FASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRQFDEILEASDGIMVARGDLGI 300

Query: 300 EIPAEKVFLAQKMMIGRCNRAGKPVICATQ 329
           EIPAEKVFLAQKMMIGRCNRAGKPVICATQ
Sbjct: 301 EIPAEKVFLAQKMMIGRCNRAGKPVICATQ 330


>gi|148235600 nucleolar protein 4 [Homo sapiens]
          Length = 638

 Score = 34.3 bits (77), Expect = 0.29
 Identities = 26/110 (23%), Positives = 47/110 (42%), Gaps = 1/110 (0%)

Query: 161 YKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPA 220
           Y+ I +++        D+      VK KG      +   GG  G+K+ + +P    D   
Sbjct: 33  YERIVQLLNGSESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVG 92

Query: 221 VSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISK 270
           V EK        VE   D++++  +    +  ++RK  G+K +  K IS+
Sbjct: 93  VDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQK-RTYKAISE 141


>gi|27545315 translational activator of mitochondrially encoded
           cytochrome c oxidase I [Homo sapiens]
          Length = 297

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 40/126 (31%), Positives = 58/126 (46%), Gaps = 20/126 (15%)

Query: 137 GATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTE 196
           G++L I   +    KC  +I  +  KN   V+ VG++   D         +KG   +V E
Sbjct: 145 GSSLLIEALSNSSHKCQADIRHILNKN-GGVMAVGARHSFD---------KKGV--IVVE 192

Query: 197 VENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRK 256
           VE+      KK VNL  A   L    E   +D+K   +++   VF  FI  AS +H+VRK
Sbjct: 193 VEDR----EKKAVNLERA---LEMAIEAGAEDVKETEDEEERNVF-KFICDASSLHQVRK 244

Query: 257 VLGEKG 262
            L   G
Sbjct: 245 KLDSLG 250


>gi|189458819 transferrin receptor [Homo sapiens]
          Length = 760

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 17/128 (13%)

Query: 139 TLKITLDNAYMEK-----CDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADF- 192
           T+K+  +N+Y+ +      DEN+  L  +N  +  ++ SK++ D   + +QVK    +  
Sbjct: 143 TIKLLNENSYVPREAGSQKDENLA-LYVENQFREFKL-SKVWRDQHFVKIQVKDSAQNSV 200

Query: 193 --------LVTEVEN-GGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFAS 243
                   LV  VEN GG +   K   + G  V     ++KD +DL   V   + +V A 
Sbjct: 201 IIVDKNGRLVYLVENPGGYVAYSKAATVTGKLVHANFGTKKDFEDLYTPVNGSIVIVRAG 260

Query: 244 FIRKASDV 251
            I  A  V
Sbjct: 261 KITFAEKV 268


>gi|189458817 transferrin receptor [Homo sapiens]
          Length = 760

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 17/128 (13%)

Query: 139 TLKITLDNAYMEK-----CDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADF- 192
           T+K+  +N+Y+ +      DEN+  L  +N  +  ++ SK++ D   + +QVK    +  
Sbjct: 143 TIKLLNENSYVPREAGSQKDENLA-LYVENQFREFKL-SKVWRDQHFVKIQVKDSAQNSV 200

Query: 193 --------LVTEVEN-GGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFAS 243
                   LV  VEN GG +   K   + G  V     ++KD +DL   V   + +V A 
Sbjct: 201 IIVDKNGRLVYLVENPGGYVAYSKAATVTGKLVHANFGTKKDFEDLYTPVNGSIVIVRAG 260

Query: 244 FIRKASDV 251
            I  A  V
Sbjct: 261 KITFAEKV 268


>gi|32483410 vitamin D-binding protein precursor [Homo sapiens]
          Length = 474

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)

Query: 76  FSHGTHEYHAETIKNVRTATESFAS---DPILYRPVAVALDTKGPEIRTGLIKGSGTAEV 132
           F  GT E  ++ +K V + TE+  +   DP  Y     AL  K  E  +      GTAE 
Sbjct: 52  FPSGTFEQVSQLVKEVVSLTEACCAEGADPDCYDTRTSALSAKSCESNSPFPVHPGTAEC 111

Query: 133 ELKKGATLKITL 144
             K+G   K+ +
Sbjct: 112 CTKEGLERKLCM 123


>gi|18079254 p53 and DNA damage-regulated protein [Homo sapiens]
          Length = 133

 Score = 29.3 bits (64), Expect = 9.4
 Identities = 18/60 (30%), Positives = 36/60 (60%), Gaps = 2/60 (3%)

Query: 245 IRKASDVHEV-RKVLGEKGKNIKIISKI-ENHEGVRRFDEILEASDGIMVARGDLGIEIP 302
           +R   +V E+  +VL +K + + + +K  +N EG+R   + L  S+ +MV  G++ I++P
Sbjct: 10  LRYLVEVEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSEDVMVCFGNMFIKMP 69


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,726,547
Number of Sequences: 37866
Number of extensions: 794972
Number of successful extensions: 1734
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1723
Number of HSP's gapped (non-prelim): 12
length of query: 531
length of database: 18,247,518
effective HSP length: 107
effective length of query: 424
effective length of database: 14,195,856
effective search space: 6019042944
effective search space used: 6019042944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.