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Search of human proteins with 122939167
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122939167 WDR45-like [Homo sapiens]
(344 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122939167 WDR45-like [Homo sapiens] 715 0.0
gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens] 323 1e-88
gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens] 320 1e-87
gi|75677331 WD repeat domain, phosphoinositide interacting 2 iso... 140 2e-33
gi|54111428 WD repeat domain, phosphoinositide interacting 2 iso... 140 2e-33
gi|75677329 WD repeat domain, phosphoinositide interacting 2 iso... 129 4e-30
gi|7661580 WD repeat domain, phosphoinositide interacting 2 isof... 129 4e-30
gi|157388939 WD repeat domain, phosphoinositide interacting 1 [H... 128 9e-30
gi|75677340 WD repeat domain, phosphoinositide interacting 2 iso... 126 3e-29
gi|32189425 WD repeat domain 69 [Homo sapiens] 49 9e-06
gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Ho... 42 8e-04
gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Ho... 42 8e-04
gi|16554629 WD repeat domain 5 [Homo sapiens] 37 0.020
gi|16554627 WD repeat domain 5 [Homo sapiens] 37 0.020
gi|23199987 WD repeat domain 5B [Homo sapiens] 37 0.020
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 37 0.034
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 37 0.034
gi|26665869 WD repeat domain 51B [Homo sapiens] 36 0.057
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 35 0.075
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 35 0.098
gi|8922735 elongator protein 2 [Homo sapiens] 34 0.22
gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens] 34 0.22
gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens] 34 0.22
gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens] 33 0.28
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 33 0.37
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H... 33 0.37
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 33 0.37
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho... 33 0.37
gi|7019503 prolactin regulatory element binding protein [Homo sa... 33 0.37
gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens] 33 0.49
>gi|122939167 WDR45-like [Homo sapiens]
Length = 344
Score = 715 bits (1845), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 1 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML 60
MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML
Sbjct: 1 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML 60
Query: 61 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI 120
FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI
Sbjct: 61 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI 120
Query: 121 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD 180
KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD
Sbjct: 121 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD 180
Query: 181 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ 240
IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ
Sbjct: 181 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ 240
Query: 241 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA 300
DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA
Sbjct: 241 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA 300
Query: 301 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL 344
FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
Sbjct: 301 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL 344
>gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens]
Length = 360
Score = 323 bits (829), Expect = 1e-88
Identities = 166/350 (47%), Positives = 226/350 (64%), Gaps = 19/350 (5%)
Query: 12 GLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEMLFRCNYLALVG 70
G+ FNQD CF C ME G R+YN +PL EK + + G +G VEML R N LALVG
Sbjct: 8 GVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVG 67
Query: 71 GGKKPKYPPNKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFT 124
GG PK+ V+IWDD K+K V+E F+ V +V++R D+IV+VL + I V++
Sbjct: 68 GGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYS 127
Query: 125 FTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTE----KPPVD 180
F NP +L F+T NPKGLC LCP+ LL FPG G +QLVDLAST+ P
Sbjct: 128 FPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAPFT 187
Query: 181 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ 240
I AH+ ++C++LN GT +A+AS+KGTLIR+FDT S + ELRRG+ A +YCINF+
Sbjct: 188 INAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFSH 247
Query: 241 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSKWSFSKFQVPSGSP 296
D+S +C SSD GTVHIFA +D + N++S+LA + +Y S+WS + F VP+ S
Sbjct: 248 DSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASFTVPAESA 307
Query: 297 CICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDD 342
CICAFG N+VIAIC DG+++K++F P G C R+ + +L++ DD
Sbjct: 308 CICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDD 357
>gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens]
Length = 361
Score = 320 bits (820), Expect = 1e-87
Identities = 166/351 (47%), Positives = 227/351 (64%), Gaps = 20/351 (5%)
Query: 12 GLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEMLFRCNYLALVG 70
G+ FNQD CF C ME G R+YN +PL EK + + G +G VEML R N LALVG
Sbjct: 8 GVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEMLHRSNLLALVG 67
Query: 71 GGKKPKYPP-NKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVF 123
GG PK+ + V+IWDD K+K V+E F+ V +V++R D+IV+VL + I V+
Sbjct: 68 GGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVY 127
Query: 124 TFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTE----KPPV 179
+F NP +L F+T NPKGLC LCP+ LL FPG G +QLVDLAST+ P
Sbjct: 128 SFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLASTKPGTSSAPF 187
Query: 180 DIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFN 239
I AH+ ++C++LN GT +A+AS+KGTLIR+FDT S + ELRRG+ A +YCINF+
Sbjct: 188 TINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYCINFS 247
Query: 240 QDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSKWSFSKFQVPSGS 295
D+S +C SSD GTVHIFA +D + N++S+LA + +Y S+WS + F VP+ S
Sbjct: 248 HDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQWSLASFTVPAES 307
Query: 296 PCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDD 342
CICAFG N+VIAIC DG+++K++F P G C R+ + +L++ DD
Sbjct: 308 ACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDICDD 358
>gi|75677331 WD repeat domain, phosphoinositide interacting 2
isoform d [Homo sapiens]
Length = 425
Score = 140 bits (353), Expect = 2e-33
Identities = 109/345 (31%), Positives = 172/345 (49%), Gaps = 39/345 (11%)
Query: 13 LLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEK-QEFLEG-GVGHVEMLFRCNYLALVG 70
LL+A FNQD+ A G ++G++ ++ + + E+ E + V VE LF + +A+V
Sbjct: 15 LLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVS 74
Query: 71 GGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPH 130
P K+ + K + +S + AVKL R R++V L+ + + HN
Sbjct: 75 -----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESL----YIHNIR 125
Query: 131 QLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDLASTEKPPVDIPAHE 185
+ V ET NP GLC L N++N LA+PG+ T G VQ+ D + + IPAH+
Sbjct: 126 DMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANM-IPAHD 184
Query: 186 GVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG-SQAANIYCINFNQDASL 244
L+ +A + GT++ATASEKGT+IR+F G + E RRG + +I + F+ D
Sbjct: 185 SPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMF 244
Query: 245 ICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP----KYFSSKWSFSK 288
+ SS+ TVHIF E K +AS S+LP + F+ +F+
Sbjct: 245 LSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFAT 304
Query: 289 FQVP-SGSPCICAFGT--EPNAVIAICADGSYYKFLFNPK--GEC 328
++P G IC+ T + ++ ADG Y + +P+ GEC
Sbjct: 305 VRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGEC 349
>gi|54111428 WD repeat domain, phosphoinositide interacting 2
isoform b [Homo sapiens]
Length = 436
Score = 140 bits (353), Expect = 2e-33
Identities = 109/345 (31%), Positives = 172/345 (49%), Gaps = 39/345 (11%)
Query: 13 LLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEK-QEFLEG-GVGHVEMLFRCNYLALVG 70
LL+A FNQD+ A G ++G++ ++ + + E+ E + V VE LF + +A+V
Sbjct: 15 LLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVS 74
Query: 71 GGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPH 130
P K+ + K + +S + AVKL R R++V L+ + + HN
Sbjct: 75 -----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESL----YIHNIR 125
Query: 131 QLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDLASTEKPPVDIPAHE 185
+ V ET NP GLC L N++N LA+PG+ T G VQ+ D + + IPAH+
Sbjct: 126 DMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANM-IPAHD 184
Query: 186 GVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG-SQAANIYCINFNQDASL 244
L+ +A + GT++ATASEKGT+IR+F G + E RRG + +I + F+ D
Sbjct: 185 SPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMF 244
Query: 245 ICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP----KYFSSKWSFSK 288
+ SS+ TVHIF E K +AS S+LP + F+ +F+
Sbjct: 245 LSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFAT 304
Query: 289 FQVP-SGSPCICAFGT--EPNAVIAICADGSYYKFLFNPK--GEC 328
++P G IC+ T + ++ ADG Y + +P+ GEC
Sbjct: 305 VRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGEC 349
>gi|75677329 WD repeat domain, phosphoinositide interacting 2
isoform c [Homo sapiens]
Length = 443
Score = 129 bits (324), Expect = 4e-30
Identities = 109/363 (30%), Positives = 172/363 (47%), Gaps = 57/363 (15%)
Query: 13 LLYAGFNQDHG------------------CFACGMENGFRVYNTDPLKEKEK-QEFLEG- 52
LL+A FNQD+ A G ++G++ ++ + + E+ E +
Sbjct: 15 LLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTE 74
Query: 53 GVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRI 112
V VE LF + +A+V P K+ + K + +S + AVKL R R+
Sbjct: 75 DVCIVERLFSSSLVAIVS-----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRL 129
Query: 113 VVVLDSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQ 167
+V L+ + + HN + V ET NP GLC L N++N LA+PG+ T G VQ
Sbjct: 130 IVCLEESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQ 185
Query: 168 LVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG 227
+ D + + IPAH+ L+ +A + GT++ATASEKGT+IR+F G + E RRG
Sbjct: 186 VFDTINLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRG 244
Query: 228 -SQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASAS 274
+ +I + F+ D + SS+ TVHIF E K +AS S
Sbjct: 245 VKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTS 304
Query: 275 FLP----KYFSSKWSFSKFQVP-SGSPCICAFGT--EPNAVIAICADGSYYKFLFNPK-- 325
+LP + F+ +F+ ++P G IC+ T + ++ ADG Y + +P+
Sbjct: 305 YLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEG 364
Query: 326 GEC 328
GEC
Sbjct: 365 GEC 367
>gi|7661580 WD repeat domain, phosphoinositide interacting 2 isoform
a [Homo sapiens]
Length = 454
Score = 129 bits (324), Expect = 4e-30
Identities = 109/363 (30%), Positives = 172/363 (47%), Gaps = 57/363 (15%)
Query: 13 LLYAGFNQDHG------------------CFACGMENGFRVYNTDPLKEKEK-QEFLEG- 52
LL+A FNQD+ A G ++G++ ++ + + E+ E +
Sbjct: 15 LLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTE 74
Query: 53 GVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRI 112
V VE LF + +A+V P K+ + K + +S + AVKL R R+
Sbjct: 75 DVCIVERLFSSSLVAIVS-----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRL 129
Query: 113 VVVLDSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQ 167
+V L+ + + HN + V ET NP GLC L N++N LA+PG+ T G VQ
Sbjct: 130 IVCLEESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQ 185
Query: 168 LVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG 227
+ D + + IPAH+ L+ +A + GT++ATASEKGT+IR+F G + E RRG
Sbjct: 186 VFDTINLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRG 244
Query: 228 -SQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASAS 274
+ +I + F+ D + SS+ TVHIF E K +AS S
Sbjct: 245 VKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTS 304
Query: 275 FLP----KYFSSKWSFSKFQVP-SGSPCICAFGT--EPNAVIAICADGSYYKFLFNPK-- 325
+LP + F+ +F+ ++P G IC+ T + ++ ADG Y + +P+
Sbjct: 305 YLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEG 364
Query: 326 GEC 328
GEC
Sbjct: 365 GEC 367
>gi|157388939 WD repeat domain, phosphoinositide interacting 1 [Homo
sapiens]
Length = 446
Score = 128 bits (321), Expect = 9e-30
Identities = 98/344 (28%), Positives = 164/344 (47%), Gaps = 45/344 (13%)
Query: 18 FNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGG-----VGHVEMLFRCNYLALVGGG 72
FNQD A G + G+++++ L E+ + + G V VE LF + + +V
Sbjct: 22 FNQDCTSLATGTKAGYKLFS---LSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHT 78
Query: 73 KKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQL 132
K P ++ ++ K + +S+ + +++L R R++V L+ I + HN +
Sbjct: 79 K-----PRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESI----YIHNIKDM 129
Query: 133 HVFETCY----NPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDLASTEKPPVDIPAHEGV 187
+ +T NP GLC L N +NS LA+PG+ T G + L D ++ K I AHEG
Sbjct: 130 KLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYD-GNSLKTVCTIAAHEGT 188
Query: 188 LSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG-SQAANIYCINFNQDASLIC 246
L+ I N G+++A+ASEKGT+IR+F G + E RRG + I + F+ D+ +C
Sbjct: 189 LAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLC 248
Query: 247 VSSDHGTVHIFAAEDPKRNKQSSLAS-ASFLPKYFSSKWSFSKFQVP------------- 292
SS+ TVHIF E ++ ++ + ++ K F + ++ QV
Sbjct: 249 ASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATAR 308
Query: 293 ---SGSPCICAFGTEPNAVIAICADGSYYKFLFN----PKGECI 329
SG IC T + A S + +++N GEC+
Sbjct: 309 LNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECV 352
Score = 32.0 bits (71), Expect = 0.83
Identities = 19/81 (23%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 169 VDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGS 228
++ + + PP + E LSC + N T +AT ++ G ++F SS + ++ +
Sbjct: 1 MEAEAADAPPGGV---ESALSCFSFNQDCTSLATGTKAG--YKLFSLSSVEQLDQVHGSN 55
Query: 229 QAANIYCINFNQDASLICVSS 249
+ ++Y + +SL+ V S
Sbjct: 56 EIPDVYIVERLFSSSLVVVVS 76
>gi|75677340 WD repeat domain, phosphoinositide interacting 2
isoform e [Homo sapiens]
Length = 384
Score = 126 bits (316), Expect = 3e-29
Identities = 96/299 (32%), Positives = 147/299 (49%), Gaps = 37/299 (12%)
Query: 57 VEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVL 116
VE LF + +A+V P K+ + K + +S + AVKL R R++V L
Sbjct: 20 VERLFSSSLVAIVS-----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL 74
Query: 117 DSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDL 171
+ + + HN + V ET NP GLC L N++N LA+PG+ T G VQ+ D
Sbjct: 75 EESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDT 130
Query: 172 ASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG-SQA 230
+ + IPAH+ L+ +A + GT++ATASEKGT+IR+F G + E RRG +
Sbjct: 131 INLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC 189
Query: 231 ANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP- 277
+I + F+ D + SS+ TVHIF E K +AS S+LP
Sbjct: 190 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS 249
Query: 278 ---KYFSSKWSFSKFQVP-SGSPCICAFGT--EPNAVIAICADGSYYKFLFNPK--GEC 328
+ F+ +F+ ++P G IC+ T + ++ ADG Y + +P+ GEC
Sbjct: 250 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGEC 308
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 48.5 bits (114), Expect = 9e-06
Identities = 43/187 (22%), Positives = 74/187 (39%), Gaps = 26/187 (13%)
Query: 82 VMIWD-DLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTF----------THNPH 130
V++WD D +K I I E+ + D +++ SM K T H
Sbjct: 243 VVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGH 302
Query: 131 QLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSC 190
+ ++C++ G + +++ + F A+T K + HEG +S
Sbjct: 303 DDEILDSCFDYTGKLIATASADGTARIFS------------AATRKCIAKLEGHEGEISK 350
Query: 191 IALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSD 250
I+ N QG + T S T RI+D +G +Q L I+ FN +++ S
Sbjct: 351 ISFNPQGNHLLTGSSDKT-ARIWDAQTGQCLQVLE--GHTDEIFSCAFNYKGNIVITGSK 407
Query: 251 HGTVHIF 257
T I+
Sbjct: 408 DNTCRIW 414
Score = 35.8 bits (81), Expect = 0.057
Identities = 26/97 (26%), Positives = 46/97 (47%), Gaps = 8/97 (8%)
Query: 184 HEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDAS 243
H + C++ N Q T +AT S T +++D +G + LR +A I ++FN
Sbjct: 176 HTAEIVCLSFNPQSTLVATGS-MDTTAKLWDIQNGEEVYTLR--GHSAEIISLSFNTSGD 232
Query: 244 LICVSSDHGTVHIFAAEDPKR-----NKQSSLASASF 275
I S TV ++ A+ ++ + ++SASF
Sbjct: 233 RIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASF 269
Score = 34.3 bits (77), Expect = 0.17
Identities = 42/182 (23%), Positives = 69/182 (37%), Gaps = 5/182 (2%)
Query: 146 VLCPNSN-NSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATAS 204
++C + N S L G+ +L D+ + E+ + H + ++ N G RI T S
Sbjct: 180 IVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV-YTLRGHSAEIISLSFNTSGDRIITGS 238
Query: 205 EKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKR 264
T++ ++D +G + L A I +FN D SLI S T ++ A + K
Sbjct: 239 FDHTVV-VWDADTGRKVNILI--GHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKC 295
Query: 265 NKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNP 324
+ L F G+ I + T +G K FNP
Sbjct: 296 VATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNP 355
Query: 325 KG 326
+G
Sbjct: 356 QG 357
>gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Homo
sapiens]
Length = 928
Score = 42.0 bits (97), Expect = 8e-04
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 9/103 (8%)
Query: 164 GHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSG----- 218
G V + + + ++ PAHE + C+A N G + T G +F +
Sbjct: 330 GQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSS 389
Query: 219 ----HLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIF 257
H + L RG A + I F+ D + VS+ GT H+F
Sbjct: 390 QCAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVF 432
>gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Homo
sapiens]
Length = 913
Score = 42.0 bits (97), Expect = 8e-04
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 9/103 (8%)
Query: 164 GHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSG----- 218
G V + + + ++ PAHE + C+A N G + T G +F +
Sbjct: 330 GQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHPWSSS 389
Query: 219 ----HLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIF 257
H + L RG A + I F+ D + VS+ GT H+F
Sbjct: 390 QCAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVF 432
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 37.4 bits (85), Expect = 0.020
Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 15/139 (10%)
Query: 125 FTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAH 184
FT H V ++P G L +S + L+ G + G + I H
Sbjct: 39 FTLAGHTKAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGKFEKT-----------ISGH 86
Query: 185 EGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASL 244
+ +S +A + + +AS+ TL +I+D SSG ++ L+ S ++C NFN ++L
Sbjct: 87 KLGISDVAWSSDSNLLVSASDDKTL-KIWDVSSGKCLKTLKGHSNY--VFCCNFNPQSNL 143
Query: 245 ICVSSDHGTVHIFAAEDPK 263
I S +V I+ + K
Sbjct: 144 IVSGSFDESVRIWDVKTGK 162
Score = 37.0 bits (84), Expect = 0.026
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 146 VLCPNSN-NSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATAS 204
V C N N S L G+ V++ D+ T K +PAH +S + N G+ I ++S
Sbjct: 132 VFCCNFNPQSNLIVSGSFDESVRIWDV-KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query: 205 EKGTLIRIFDTSSGHLIQEL 224
G L RI+DT+SG ++ L
Sbjct: 191 YDG-LCRIWDTASGQCLKTL 209
Score = 32.3 bits (72), Expect = 0.63
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 181 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ 240
+ H + C N Q I + S + +RI+D +G ++ L S + ++FN+
Sbjct: 125 LKGHSNYVFCCNFNPQSNLIVSGSFDES-VRIWDVKTGKCLKTLPAHSDPVS--AVHFNR 181
Query: 241 DASLICVSSDHGTVHIF 257
D SLI SS G I+
Sbjct: 182 DGSLIVSSSYDGLCRIW 198
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 37.4 bits (85), Expect = 0.020
Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 15/139 (10%)
Query: 125 FTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAH 184
FT H V ++P G L +S + L+ G + G + I H
Sbjct: 39 FTLAGHTKAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGKFEKT-----------ISGH 86
Query: 185 EGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASL 244
+ +S +A + + +AS+ TL +I+D SSG ++ L+ S ++C NFN ++L
Sbjct: 87 KLGISDVAWSSDSNLLVSASDDKTL-KIWDVSSGKCLKTLKGHSNY--VFCCNFNPQSNL 143
Query: 245 ICVSSDHGTVHIFAAEDPK 263
I S +V I+ + K
Sbjct: 144 IVSGSFDESVRIWDVKTGK 162
Score = 37.0 bits (84), Expect = 0.026
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 146 VLCPNSN-NSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATAS 204
V C N N S L G+ V++ D+ T K +PAH +S + N G+ I ++S
Sbjct: 132 VFCCNFNPQSNLIVSGSFDESVRIWDV-KTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query: 205 EKGTLIRIFDTSSGHLIQEL 224
G L RI+DT+SG ++ L
Sbjct: 191 YDG-LCRIWDTASGQCLKTL 209
Score = 32.3 bits (72), Expect = 0.63
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 181 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ 240
+ H + C N Q I + S + +RI+D +G ++ L S + ++FN+
Sbjct: 125 LKGHSNYVFCCNFNPQSNLIVSGSFDES-VRIWDVKTGKCLKTLPAHSDPVS--AVHFNR 181
Query: 241 DASLICVSSDHGTVHIF 257
D SLI SS G I+
Sbjct: 182 DGSLIVSSSYDGLCRIW 198
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 37.4 bits (85), Expect = 0.020
Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 184 HEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDAS 243
H +S +A + +R+ +AS+ TL +++D SG ++ L+ S ++C NFN ++
Sbjct: 82 HNLEISDVAWSSDSSRLVSASDDKTL-KLWDVRSGKCLKTLKGHSNY--VFCCNFNPPSN 138
Query: 244 LICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWS 285
LI S TV I+ + K K S S +F+ S
Sbjct: 139 LIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGS 180
>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit
isoform a [Homo sapiens]
Length = 353
Score = 36.6 bits (83), Expect = 0.034
Identities = 43/163 (26%), Positives = 66/163 (40%), Gaps = 29/163 (17%)
Query: 80 NKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLH-----V 134
NKV+ D K K I V +D V+V DS FT T+ H + V
Sbjct: 64 NKVLCMDWCKDKRRI----------VSSSQDGKVIVWDS----FT-TNKEHAVTMPCTWV 108
Query: 135 FETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALN 194
Y P G + C +N +P T + ++A+ +K + H LS +
Sbjct: 109 MACAYAPSGCAIACGGLDNKCSVYPLTFDKN---ENMAAKKK---SVAMHTNYLSACSFT 162
Query: 195 LQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCIN 237
+I TAS GT ++D SG L+Q A++ C++
Sbjct: 163 NSDMQILTASGDGT-CALWDVESGQLLQSFH--GHGADVLCLD 202
>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
isoform b [Homo sapiens]
Length = 395
Score = 36.6 bits (83), Expect = 0.034
Identities = 43/163 (26%), Positives = 66/163 (40%), Gaps = 29/163 (17%)
Query: 80 NKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLH-----V 134
NKV+ D K K I V +D V+V DS FT T+ H + V
Sbjct: 106 NKVLCMDWCKDKRRI----------VSSSQDGKVIVWDS----FT-TNKEHAVTMPCTWV 150
Query: 135 FETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALN 194
Y P G + C +N +P T + ++A+ +K + H LS +
Sbjct: 151 MACAYAPSGCAIACGGLDNKCSVYPLTFDKN---ENMAAKKK---SVAMHTNYLSACSFT 204
Query: 195 LQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCIN 237
+I TAS GT ++D SG L+Q A++ C++
Sbjct: 205 NSDMQILTASGDGT-CALWDVESGQLLQSFH--GHGADVLCLD 244
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 35.8 bits (81), Expect = 0.057
Identities = 25/106 (23%), Positives = 44/106 (41%), Gaps = 15/106 (14%)
Query: 139 YNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGT 198
+NP G C+ S+ ++ + K H G ++CI+ + G
Sbjct: 194 FNPSGTCIASAGSDQTVKVWD------------VRVNKLLQHYQVHSGGVNCISFHPSGN 241
Query: 199 RIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASL 244
+ TAS GTL +I D G LI L+ ++ ++F++ L
Sbjct: 242 YLITASSDGTL-KILDLLEGRLIYTLQ--GHTGPVFTVSFSKGGEL 284
Score = 31.6 bits (70), Expect = 1.1
Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 186 GVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLI 245
G + + N GT IA+A T ++++D L+Q + S N CI+F+ + +
Sbjct: 187 GFANFVDFNPSGTCIASAGSDQT-VKVWDVRVNKLLQHYQVHSGGVN--CISFHPSGNYL 243
Query: 246 CVSSDHGTVHI 256
+S GT+ I
Sbjct: 244 ITASSDGTLKI 254
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 35.4 bits (80), Expect = 0.075
Identities = 28/129 (21%), Positives = 61/129 (47%), Gaps = 9/129 (6%)
Query: 155 LLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFD 214
L+ G + G +++ ++ T +++ H+ V+ ++ G+ I ++ + +RI+D
Sbjct: 124 LVLATGLNDGQIKIWEV-QTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWD 182
Query: 215 TSS-GHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAED-----PKRNKQS 268
+ G IQ L Q +YC + + D S++C ++ +V +++ QS
Sbjct: 183 LNKHGKQIQVLSGHLQW--VYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQS 240
Query: 269 SLASASFLP 277
S+ S F P
Sbjct: 241 SVVSCDFSP 249
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 35.0 bits (79), Expect = 0.098
Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 181 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ 240
+ H G + + N G+ + +AS T + ++D+ +G ++ L+ + N C +
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKT-VAVWDSETGERVKRLKGHTSFVNS-CYPARR 162
Query: 241 DASLICVSSDHGTVHIF 257
L+C SD GTV ++
Sbjct: 163 GPQLVCTGSDDGTVKLW 179
>gi|8922735 elongator protein 2 [Homo sapiens]
Length = 826
Score = 33.9 bits (76), Expect = 0.22
Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
Query: 196 QGTRIATAS-EKGTLIRIFDTSSGHLIQELRRGSQAAN---IYCINFNQDASLICVSSDH 251
Q R+ +AS +K ++ D SG ++++R G N Y FN+D S+I + H
Sbjct: 303 QPVRLLSASMDKTMILWAPDEESGVWLEQVRVGEVGGNTLGFYDCQFNEDGSMIIAHAFH 362
Query: 252 GTVHIF 257
G +H++
Sbjct: 363 GALHLW 368
Score = 28.5 bits (62), Expect = 9.2
Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 2/52 (3%)
Query: 221 IQELRRGSQAANIYCINF--NQDASLICVSSDHGTVHIFAAEDPKRNKQSSL 270
+Q L G+ A C++F N D ++ +D +HIFA ++ + K SL
Sbjct: 152 LQTLNFGNGFALALCLSFLPNTDVPILACGNDDCRIHIFAQQNDQFQKVLSL 203
>gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]
Length = 1170
Score = 33.9 bits (76), Expect = 0.22
Identities = 22/96 (22%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 161 THTGHVQLVDLASTEKPPVD--IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSG 218
T T +L LA+ ++ + H G + + N Q ++ T+ E G +I ++ G
Sbjct: 45 TQTDDAKLRGLAAPSNLSMNQTLEGHSGSVQVVTWNEQYQKLTTSDENGLII-VWMLYKG 103
Query: 219 HLIQELRRGSQAANIYCINFNQDASLICVSSDHGTV 254
I+E+ + + +++N D IC+ + G V
Sbjct: 104 SWIEEMINNRNKSVVRSMSWNADGQKICIVYEDGAV 139
>gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]
Length = 1181
Score = 33.9 bits (76), Expect = 0.22
Identities = 22/96 (22%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 161 THTGHVQLVDLASTEKPPVD--IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSG 218
T T +L LA+ ++ + H G + + N Q ++ T+ E G +I ++ G
Sbjct: 45 TQTDDAKLRGLAAPSNLSMNQTLEGHSGSVQVVTWNEQYQKLTTSDENGLII-VWMLYKG 103
Query: 219 HLIQELRRGSQAANIYCINFNQDASLICVSSDHGTV 254
I+E+ + + +++N D IC+ + G V
Sbjct: 104 SWIEEMINNRNKSVVRSMSWNADGQKICIVYEDGAV 139
>gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens]
Length = 466
Score = 33.5 bits (75), Expect = 0.28
Identities = 25/80 (31%), Positives = 42/80 (52%), Gaps = 4/80 (5%)
Query: 180 DIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQA--ANIYCIN 237
+I H ++C+ + G R ATAS G I I+D +G + L GS+A IY I+
Sbjct: 44 NIDDHSRFVNCVRFSPDGNRFATASADGQ-IYIYDGKTGEKVCAL-GGSKAHDGGIYAIS 101
Query: 238 FNQDASLICVSSDHGTVHIF 257
++ D++ + +S T I+
Sbjct: 102 WSPDSTHLLSASGDKTSKIW 121
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 33.1 bits (74), Expect = 0.37
Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 15/114 (13%)
Query: 129 PHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVL 188
PH V+ C++ G + ++ +L F A T + ++I AHE +
Sbjct: 613 PHTDAVYHACFSEDGQRIASCGADKTLQVFK------------AETGEKLLEIKAHEDEV 660
Query: 189 SCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDA 242
C A + IAT S ++I+++ +G L+ S+ N C +F +
Sbjct: 661 LCCAFSTDDRFIATCS-VDKKVKIWNSMTGELVHTYDEHSEQVN--CCHFTNSS 711
Score = 31.6 bits (70), Expect = 1.1
Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 177 PPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLI 221
P ++ H G + C A ++ T +AT + G IRI++ S+G L+
Sbjct: 1076 PLHELRGHNGCVRCSAFSVDSTLLATGDDNGE-IRIWNVSNGELL 1119
>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
sapiens]
Length = 1248
Score = 33.1 bits (74), Expect = 0.37
Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 15/114 (13%)
Query: 129 PHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVL 188
PH V+ C++ G + ++ +L F A T + ++I AHE +
Sbjct: 613 PHTDAVYHACFSEDGQRIASCGADKTLQVFK------------AETGEKLLEIKAHEDEV 660
Query: 189 SCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDA 242
C A + IAT S ++I+++ +G L+ S+ N C +F +
Sbjct: 661 LCCAFSTDDRFIATCS-VDKKVKIWNSMTGELVHTYDEHSEQVN--CCHFTNSS 711
Score = 31.6 bits (70), Expect = 1.1
Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 177 PPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLI 221
P ++ H G + C A ++ T +AT + G IRI++ S+G L+
Sbjct: 1119 PLHELRGHNGCVRCSAFSVDSTLLATGDDNGE-IRIWNVSNGELL 1162
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 33.1 bits (74), Expect = 0.37
Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 15/114 (13%)
Query: 129 PHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVL 188
PH V+ C++ G + ++ +L F A T + ++I AHE +
Sbjct: 602 PHTDAVYHACFSEDGQRIASCGADKTLQVFK------------AETGEKLLEIKAHEDEV 649
Query: 189 SCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDA 242
C A + IAT S ++I+++ +G L+ S+ N C +F +
Sbjct: 650 LCCAFSTDDRFIATCS-VDKKVKIWNSMTGELVHTYDEHSEQVN--CCHFTNSS 700
Score = 31.6 bits (70), Expect = 1.1
Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 177 PPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLI 221
P ++ H G + C A ++ T +AT + G IRI++ S+G L+
Sbjct: 1065 PLHELRGHNGCVRCSAFSVDSTLLATGDDNGE-IRIWNVSNGELL 1108
>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
sapiens]
Length = 1237
Score = 33.1 bits (74), Expect = 0.37
Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 15/114 (13%)
Query: 129 PHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVL 188
PH V+ C++ G + ++ +L F A T + ++I AHE +
Sbjct: 602 PHTDAVYHACFSEDGQRIASCGADKTLQVFK------------AETGEKLLEIKAHEDEV 649
Query: 189 SCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDA 242
C A + IAT S ++I+++ +G L+ S+ N C +F +
Sbjct: 650 LCCAFSTDDRFIATCS-VDKKVKIWNSMTGELVHTYDEHSEQVN--CCHFTNSS 700
Score = 31.6 bits (70), Expect = 1.1
Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 177 PPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLI 221
P ++ H G + C A ++ T +AT + G IRI++ S+G L+
Sbjct: 1108 PLHELRGHNGCVRCSAFSVDSTLLATGDDNGE-IRIWNVSNGELL 1151
>gi|7019503 prolactin regulatory element binding protein [Homo
sapiens]
Length = 417
Score = 33.1 bits (74), Expect = 0.37
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 146 VLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASE 205
V+C N +N+LLA GT G+V++ + S EK ++ AHEG + +AL G + +
Sbjct: 159 VVCFNHDNTLLATGGT-DGYVRVWKVPSLEK-VLEFKAHEGEIEDLALGPDGKLVTVGRD 216
>gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens]
Length = 606
Score = 32.7 bits (73), Expect = 0.49
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 184 HEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQA--ANIYCINFNQD 241
H ++C+ + G R ATAS G I I+D +G + L GS+A IY I+++ D
Sbjct: 188 HSRFVNCVRFSPDGNRFATASADGQ-IYIYDGKTGEKVCAL-GGSKAHDGGIYAISWSPD 245
Query: 242 ASLICVSSDHGTVHIF 257
++ + +S T I+
Sbjct: 246 STHLLSASGDKTSKIW 261
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,170,894
Number of Sequences: 37866
Number of extensions: 636640
Number of successful extensions: 1392
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 1322
Number of HSP's gapped (non-prelim): 106
length of query: 344
length of database: 18,247,518
effective HSP length: 103
effective length of query: 241
effective length of database: 14,347,320
effective search space: 3457704120
effective search space used: 3457704120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.