Search of human proteins with 32567786

Search of human proteins with 32567786

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32567786 keratin 6L [Homo sapiens]
         (535 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32567786 keratin 6L [Homo sapiens]                                1045   0.0  
gi|119703753 keratin 6B [Homo sapiens]                                629   e-180
gi|5031839 keratin 6A [Homo sapiens]                                  628   e-180
gi|155969697 keratin 6C [Homo sapiens]                                625   e-179
gi|119395754 keratin 5 [Homo sapiens]                                 610   e-174
gi|153791158 keratin 75 [Homo sapiens]                                600   e-171
gi|109148552 keratin 3 [Homo sapiens]                                 586   e-167
gi|119395750 keratin 1 [Homo sapiens]                                 583   e-166
gi|109255249 keratin 4 [Homo sapiens]                                 580   e-166
gi|194018511 keratin 77 [Homo sapiens]                                566   e-161
gi|153791670 keratin 76 [Homo sapiens]                                563   e-160
gi|47132620 keratin 2 [Homo sapiens]                                  555   e-158
gi|28173564 keratin 73 [Homo sapiens]                                 538   e-153
gi|15618995 keratin 71 [Homo sapiens]                                 535   e-152
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       518   e-147
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      518   e-147
gi|148612803 keratin 6 irs4 [Homo sapiens]                            514   e-146
gi|67782365 keratin 7 [Homo sapiens]                                  479   e-135
gi|89357932 keratin 5b [Homo sapiens]                                 464   e-131
gi|4504919 keratin 8 [Homo sapiens]                                   460   e-129
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    458   e-129
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      451   e-127
gi|27477127 keratin 82 [Homo sapiens]                                 410   e-114
gi|4504935 keratin 85 [Homo sapiens]                                  407   e-113
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   389   e-108
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   389   e-108
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   389   e-108
gi|14318422 keratin 86 [Homo sapiens]                                 389   e-108
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   388   e-108
gi|169790841 keratin 83 [Homo sapiens]                                385   e-107

>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score = 1045 bits (2701), Expect = 0.0
 Identities = 535/535 (100%), Positives = 535/535 (100%)

Query: 1   MRSSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSR 60
           MRSSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSR
Sbjct: 1   MRSSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSR 60

Query: 61  SLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQEVTVN 120
           SLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQEVTVN
Sbjct: 61  SLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQEVTVN 120

Query: 121 QSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQ 180
           QSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQ
Sbjct: 121 QSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQ 180

Query: 181 GQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINK 240
           GQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINK
Sbjct: 181 GQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINK 240

Query: 241 HTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVV 300
           HTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVV
Sbjct: 241 HTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVV 300

Query: 301 LSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKN 360
           LSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKN
Sbjct: 301 LSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKN 360

Query: 361 EIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKE 420
           EIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKE
Sbjct: 361 EIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKE 420

Query: 421 DLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGG 480
           DLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGG
Sbjct: 421 DLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGG 480

Query: 481 AASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVSAGTSILRKTTTVKTSSQRY 535
           AASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVSAGTSILRKTTTVKTSSQRY
Sbjct: 481 AASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVSAGTSILRKTTTVKTSSQRY 535


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  629 bits (1621), Expect = e-180
 Identities = 354/564 (62%), Positives = 415/564 (73%), Gaps = 37/564 (6%)

Query: 3   SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGG-GAHCGPGTGGFGSRS 61
           S+  R   S++ GFS+NSA     S  R+ FSS++VSRS GSGG G  CG    GFGSRS
Sbjct: 5   STTIRSHSSSRRGFSANSARLPGVS--RSGFSSISVSRSRGSGGLGGACGGA--GFGSRS 60

Query: 62  LYNLGGHKSISV------------SVAGGAL-LGRALGGFGFGSRAFMGQGAGRQT---- 104
           LY LGG K IS+            S AGG+   G A  GFGFG  A +G G G       
Sbjct: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120

Query: 105 -FG----PACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDK 159
            FG    P CPPGGIQEVTVNQSLLTPL+++IDP IQRVR +EREQIKTLNNKFASFIDK
Sbjct: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDK 180

Query: 160 VRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSE 219
           VRFLEQQNKVL+TKW LLQEQG      R NLEPLFE Y+ ++R  LD +  ERGRLDSE
Sbjct: 181 VRFLEQQNKVLDTKWTLLQEQGTK--TVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSE 238

Query: 220 LRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFL 279
           LRN+QDLVED KNKYEDEINK TAAENEFV LKKDVDAAYM +++L  K  TLT EI+FL
Sbjct: 239 LRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFL 298

Query: 280 QQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQT 339
           + LY+ ELSQ+QTH+S+T+VVLSMDNNRNLDLDSIIAEVKAQYE IAQRSRAEAE+WYQT
Sbjct: 299 RALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQT 358

Query: 340 KYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGEL 399
           KYEELQ+TAG+HGD+LR+TK EIAE+ R IQRL+ E D  KKQC  LQ AIA+AEQRGE+
Sbjct: 359 KYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEM 418

Query: 400 ALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSG 459
           ALKDA+ KL  L+ AL +AK+DL RLL++YQELMNVKLALDVEIATYRKLLE EE R++G
Sbjct: 419 ALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNG 478

Query: 460 ECPSAVSISVTGNSTTVCGGGAASFGGGISLG-------GSGGATKGGFSTNVGYSTVKG 512
           E    V+ISV  ++ +   GGA+  G G+ LG       GSG    GGFS++ G +T  G
Sbjct: 479 EGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRATGGG 538

Query: 513 -GPVSAGTSILRKTTTVKTSSQRY 535
              V  G+S ++ TTT  +S + Y
Sbjct: 539 LSSVGGGSSTIKYTTTSSSSRKSY 562


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  628 bits (1619), Expect = e-180
 Identities = 356/564 (63%), Positives = 414/564 (73%), Gaps = 37/564 (6%)

Query: 3   SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGG-GAHCGPGTGGFGSRS 61
           S+  R   S++ GFS+NSA     S  R+ FSSV+VSRS GSGG G  CG    GFGSRS
Sbjct: 5   STTIRSHSSSRRGFSANSARLPGVS--RSGFSSVSVSRSRGSGGLGGACGGA--GFGSRS 60

Query: 62  LYNLGGHKSISV------------SVAGGAL-LGRALGGFGFGSRAFMGQGAGRQT---- 104
           LY LGG K IS+            S AGG+   G A  GFGFG  A +G G G       
Sbjct: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120

Query: 105 -FG----PACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDK 159
            FG    P CPPGGIQEVTVNQSLLTPL+++IDP IQRVR +EREQIKTLNNKFASFIDK
Sbjct: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDK 180

Query: 160 VRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSE 219
           VRFLEQQNKVLETKW LLQEQG      R NLEPLFE Y+ ++R  LD +  ERGRLDSE
Sbjct: 181 VRFLEQQNKVLETKWTLLQEQGTK--TVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSE 238

Query: 220 LRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFL 279
           LR +QDLVEDFKNKYEDEINK TAAENEFV LKKDVDAAYM +++L  K  TLT EI+FL
Sbjct: 239 LRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFL 298

Query: 280 QQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQT 339
           + LY+ ELSQ+QTH+S+T+VVLSMDNNRNLDLDSIIAEVKAQYE IAQRSRAEAE+WYQT
Sbjct: 299 RALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQT 358

Query: 340 KYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGEL 399
           KYEELQVTAG+HGD+LR+TK EIAE+ R IQRL+ E D  KKQC  LQ AIA+AEQRGE+
Sbjct: 359 KYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEM 418

Query: 400 ALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSG 459
           ALKDA+ KL  L+ AL +AK+DL RLL++YQELMNVKLALDVEIATYRKLLE EE R++G
Sbjct: 419 ALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNG 478

Query: 460 ECPSAVSISVTGNSTTVCGGGAASFGGGISLG-------GSGGATKGGFSTNVGYSTVKG 512
           E    V+ISV  ++ +   GGA+  G G+ LG       GSG    GGFS++ G +   G
Sbjct: 479 EGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGG 538

Query: 513 -GPVSAGTSILRKTTTVKTSSQRY 535
              V  G+S ++ TTT  +S + Y
Sbjct: 539 LSSVGGGSSTIKYTTTSSSSRKSY 562


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  625 bits (1612), Expect = e-179
 Identities = 353/564 (62%), Positives = 414/564 (73%), Gaps = 37/564 (6%)

Query: 3   SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGG-GAHCGPGTGGFGSRS 61
           S+  R   S++ GFS+NSA     S  R+ FSS++VSRS GSGG G  CG    GFGSRS
Sbjct: 5   STTIRSHSSSRRGFSANSARLPGVS--RSGFSSISVSRSRGSGGLGGACGGA--GFGSRS 60

Query: 62  LYNLGGHKSISV------------SVAGGAL-LGRALGGFGFGSRAFMGQGAGRQT---- 104
           LY LGG K IS+            S AGG+   G A  GFGFG  A +G G G       
Sbjct: 61  LYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAG 120

Query: 105 -FG----PACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDK 159
            FG    P CPPGGIQEVTVNQSLLTPL+++IDP IQRVR +EREQIKTLNNKFASFIDK
Sbjct: 121 GFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDK 180

Query: 160 VRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSE 219
           VRFLEQQNKVL+TKW LLQEQG      R NLEPLFE Y+ ++R  LD +  ERGRLDSE
Sbjct: 181 VRFLEQQNKVLDTKWTLLQEQGTK--TVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSE 238

Query: 220 LRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFL 279
           LRN+QDLVED KNKYEDEINK TAAENEFV LKKDVDAAYM +++L  K  TLT EI+FL
Sbjct: 239 LRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFL 298

Query: 280 QQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQT 339
           + LY+ ELSQ+QTH+S+T+VVLSMDNNRNLDLDSIIAEVKAQYE IAQRSRAEAE+WYQT
Sbjct: 299 RALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQT 358

Query: 340 KYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGEL 399
           KYEELQVTAG+HGD+LR+TK EIAE+ R IQRL+ E D  KKQC  LQ AIA+AEQRGE+
Sbjct: 359 KYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEM 418

Query: 400 ALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSG 459
           ALKDA+ KL  L+ AL +AK+DL RLL++YQELMNVKLALDVEIATYRKLLE EE R++G
Sbjct: 419 ALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNG 478

Query: 460 ECPSAVSISVTGNSTTVCGGGAASFGGGISLG-------GSGGATKGGFSTNVGYSTVKG 512
           E    V++SV  ++ +   GGA+  G G+ LG       GSG    GGFS++ G +   G
Sbjct: 479 EGVGQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAIGGG 538

Query: 513 -GPVSAGTSILRKTTTVKTSSQRY 535
              V  G+S ++ TTT  +S + Y
Sbjct: 539 LSSVGGGSSTIKYTTTSSSSRKSY 562


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  610 bits (1572), Expect = e-174
 Identities = 336/543 (61%), Positives = 396/543 (72%), Gaps = 37/543 (6%)

Query: 3   SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHC------GPGTGG 56
           S  S  ++ + G  S ++AS  + S +RTSF+SV  SRS G GGG           G GG
Sbjct: 2   SRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSV--SRSGGGGGGGFGRVSLAGACGVGG 59

Query: 57  FGSRSLYNLGGHKSISVSVAGGALLGR----ALGGFGFGSRAFMGQGAGRQTFG------ 106
           +GSRSLYNLGG K IS+S +GG+   R    A GG+GFG  A  G G G    G      
Sbjct: 60  YGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGG 119

Query: 107 -------------PACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKF 153
                        P CPPGGIQEVTVNQSLLTPL+++IDP IQRVRT+EREQIKTLNNKF
Sbjct: 120 GAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKF 179

Query: 154 ASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSER 213
           ASFIDKVRFLEQQNKVL+TKW LLQEQG      R NLEPLFE Y+ ++R  LD +  ER
Sbjct: 180 ASFIDKVRFLEQQNKVLDTKWTLLQEQGTK--TVRQNLEPLFEQYINNLRRQLDSIVGER 237

Query: 214 GRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLT 273
           GRLDSELRN+QDLVEDFKNKYEDEINK T AENEFV+LKKDVDAAYM +++L  KV  L 
Sbjct: 238 GRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALM 297

Query: 274 QEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEA 333
            EI+F++  ++ ELSQ+QTHVS+T+VVLSMDNNRNLDLDSIIAEVKAQYE IA RSR EA
Sbjct: 298 DEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEA 357

Query: 334 EAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEA 393
           E+WYQTKYEELQ TAG+HGD+LR+TK+EI+E+ R IQRL+ E D  KKQC  LQ AIA+A
Sbjct: 358 ESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADA 417

Query: 394 EQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESE 453
           EQRGELALKDA+ KL +L+ AL +AK+D+ RLLR+YQELMN KLALDVEIATYRKLLE E
Sbjct: 418 EQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGE 477

Query: 454 ESRMSGECPSAVSISVTGNSTTVCGGGAASFGGGISLGGSGGATKGGF---STNVGYSTV 510
           E R+SGE    V+ISV  +S +   G  + +GGG+  GG GG   GG    S+   YS+ 
Sbjct: 478 ECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLG-GGLGGGLGGGLAGGSSGSYYSSS 536

Query: 511 KGG 513
            GG
Sbjct: 537 SGG 539


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  600 bits (1546), Expect = e-171
 Identities = 336/551 (60%), Positives = 410/551 (74%), Gaps = 25/551 (4%)

Query: 2   RSSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRS-SGSGGGAHCGPGTGGFGSR 60
           +SS++ Q+ S +G FS+ SA   +  ++R  FSSV+V+RS +GSGG          FGSR
Sbjct: 4   QSSITFQSGSRRG-FSTTSAITPAAGRSR--FSSVSVARSAAGSGGLGRISSAGASFGSR 60

Query: 61  SLYNLGGHKSISVSVAGGALL----GRALGGFGFGSRAFMGQGAGRQTFGPA---CPPGG 113
           SLYNLGG K +S++  G +      GRA   FG  S    G G G    GP+   CPPGG
Sbjct: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGG 120

Query: 114 IQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETK 173
           IQEVTVNQSLLTPLH++IDP IQRVR +EREQIKTLNNKFASFIDKVRFLEQQNKVLETK
Sbjct: 121 IQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETK 180

Query: 174 WALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNK 233
           WALLQEQG      R NLEPLF++Y   +R  L+ + +ERGRL++ELRN+QD+VEDFK +
Sbjct: 181 WALLQEQGSR--TVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVR 238

Query: 234 YEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTH 293
           YEDEINK TAAENEFV LKKDVDAAYM +++L  KV +L +EI+F+  +++ ELSQ+QT 
Sbjct: 239 YEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQ 298

Query: 294 VSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGD 353
           V +T+VVLSMDNNRNLDLDSIIAEVKAQYE IA RSRAEAE+WYQTKYEELQVTAG+HGD
Sbjct: 299 VGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGD 358

Query: 354 NLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDV 413
           +LR+TK EI+E+ R IQRL+ E D+ KKQC  LQTAIA+AEQRGELALKDA+ KL DL+ 
Sbjct: 359 DLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEE 418

Query: 414 ALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSIS-VTGN 472
           AL +AK+D+ RLLR+YQELMN+KLALDVEIATYRKLLE EE R+SGE  S V+IS VT  
Sbjct: 419 ALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTST 478

Query: 473 STTVCGGGAASFGGGISLGGSGG---ATKGGFSTNVGY------STVKGGPVSAGTSILR 523
            ++  G G++  GG + LGG  G    T GG S   G       +T   G   +G+S+  
Sbjct: 479 LSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVKF 538

Query: 524 KTTTVKTSSQR 534
            +TT  +SSQ+
Sbjct: 539 VSTT--SSSQK 547


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  586 bits (1511), Expect = e-167
 Identities = 344/580 (59%), Positives = 393/580 (67%), Gaps = 71/580 (12%)

Query: 5   VSRQTYSTKGGFSSNSASGGSGSQARTSFSS--VTVSRSSGSGGGAH-CGPGTGGFGSRS 61
           +SRQ   T GG S     G SG  A  S SS    V+ S G+GGGA+    G GGFGSRS
Sbjct: 1   MSRQASKTSGGGSQ----GFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRS 56

Query: 62  LYNLGGHKSISVSVA----------GG----ALLGRALGGFG----------FGSRAFMG 97
           LYNLGG+KSIS+SVA          GG    A  G   GGFG          FG    MG
Sbjct: 57  LYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMG 116

Query: 98  QGAGRQT-------------------------------------FGPACPPGGIQEVTVN 120
            G G                                        FGP   PGGIQEVT+N
Sbjct: 117 GGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTIN 176

Query: 121 QSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQ 180
           QSLL PL+VEIDP+I +V+ QEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQ+Q
Sbjct: 177 QSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQ 236

Query: 181 GQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINK 240
           G +     NNLEPLFE ++  +RS LD +  ERGRLDSEL+N++DLVEDFK KYEDEINK
Sbjct: 237 GTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINK 296

Query: 241 HTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVV 300
            TAAENEFV LKKDVD+AYM +++L  KV  L  EIDFL+ LY+ ELSQ+Q+H+S+T+VV
Sbjct: 297 RTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVV 356

Query: 301 LSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKN 360
           LSMDNNR+LDLDSIIAEV+AQYE IAQRS+AEAEA YQTK  ELQ TAG+HGD+LR+TK+
Sbjct: 357 LSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKS 416

Query: 361 EIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKE 420
           EI EL R IQRL+ E +  KKQ   LQTAIAEAEQ GE+ALKDA  KL +L  AL QAK+
Sbjct: 417 EIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKD 476

Query: 421 DLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTT--VCG 478
           DL RLLRDYQELMNVKLALDVEIATYRKLLE EE RMSGECPSAVSISV  +STT    G
Sbjct: 477 DLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAG 536

Query: 479 GGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVSAG 518
           G    +GGG+  GG GG    G  +  G+    GG +  G
Sbjct: 537 GYGGGYGGGMG-GGLGGGFSAGGGSGSGFGRGGGGGIGGG 575



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 34/91 (37%), Positives = 37/91 (40%), Gaps = 7/91 (7%)

Query: 3   SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGT-GGFGSRS 61
           S VS  T S   G       GG G      FS+      SGSG G   G G  GGFG  S
Sbjct: 524 SVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSA---GGGSGSGFGRGGGGGIGGGFGGGS 580

Query: 62  LYNLGGHKSISVSVAGGALLGRALGGFGFGS 92
               GG    S+S   GA  G + GGF   S
Sbjct: 581 SGFSGGSGFGSIS---GARYGVSGGGFSSAS 608


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  583 bits (1503), Expect = e-166
 Identities = 327/562 (58%), Positives = 399/562 (70%), Gaps = 49/562 (8%)

Query: 2   RSSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGG--AHCGPGTG---- 55
           R   SR  Y + GGFSS SA G    Q RT+ SS   +R SG GGG  + CG G G    
Sbjct: 3   RQFSSRSGYRSGGGFSSGSA-GIINYQRRTTSSS---TRRSGGGGGRFSSCGGGGGSFGA 58

Query: 56  --GFGSRSLYNLGGHKSISVSVA-----------------------------GGALLGRA 84
             GFGSRSL NLGG KSIS+SVA                             GG + G  
Sbjct: 59  GGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGG 118

Query: 85  LGGFGFGSRAFMGQGAG----RQTFGPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRT 140
            GGFG G   F G G G       +GP CPPGGIQEVT+NQSLL PL+VEIDPEIQ+V++
Sbjct: 119 FGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKS 178

Query: 141 QEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLG 200
           +EREQIK+LNN+FASFIDKVRFLEQQN+VL+TKW LLQ+   +     +NLEP FE+++ 
Sbjct: 179 REREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQ--VDTSTRTHNLEPYFESFIN 236

Query: 201 SMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYM 260
           ++R  +D+L+S++ RLDSEL+N+QD+VED++NKYEDEINK T AENEFV +KKDVD AYM
Sbjct: 237 NLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYM 296

Query: 261 GRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKA 320
            ++DL  K+  L QEIDFL  LY+ ELSQ+QT +S TNV+LSMDNNR+LDLDSIIAEVKA
Sbjct: 297 TKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKA 356

Query: 321 QYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAK 380
           QYE IAQ+S+AEAE+ YQ+KYEELQ+TAG+HGD++R++K EI+EL R IQRL+ E D  K
Sbjct: 357 QYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVK 416

Query: 381 KQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALD 440
           KQ   LQ +I++AEQRGE ALKDA+ KL DL+ AL QAKEDL RLLRDYQELMN KLALD
Sbjct: 417 KQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALD 476

Query: 441 VEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGGG--ISLGGSGGATK 498
           +EIATYR LLE EESRMSGEC   VS+SV+ + TT+ GGG+   GGG   S G S G+  
Sbjct: 477 LEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGG 536

Query: 499 GGFSTNVGYSTVKGGPVSAGTS 520
           G + +  G    +G   S G+S
Sbjct: 537 GSYGSGGGGGGGRGSYGSGGSS 558



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 33/104 (31%), Positives = 43/104 (41%), Gaps = 4/104 (3%)

Query: 14  GGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISV 73
           GG+ S  +S GSG  +  S       R S   GG+  G G G +GS      GGH S   
Sbjct: 523 GGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGG--GGGGHGSYGS 580

Query: 74  SVAGGALLGRALGGFG--FGSRAFMGQGAGRQTFGPACPPGGIQ 115
             + G   G + GG G   G R   G  +G    G     GG++
Sbjct: 581 GSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVK 624



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 5/92 (5%)

Query: 11  STKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAH-CGPGTGGFGSR-SLYNLGGH 68
           S+ G    +  SGG G   R S+ S     S GSGGG++  G G GG GS  S  + GG+
Sbjct: 530 SSYGSGGGSYGSGGGGGGGRGSYGSG--GSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGY 587

Query: 69  KSISVSVAGGALLGRALGGFGFGSRAFMGQGA 100
           +  S    GG+  GR  GG G    +  G+G+
Sbjct: 588 RGGSGGGGGGSSGGRGSGG-GSSGGSIGGRGS 618



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 5/93 (5%)

Query: 9   TYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAH--CGPGTGGFGSRSLYNLG 66
           +Y + GG      S GSG    +S+ S   S  SG GGG H   G G+   G R     G
Sbjct: 538 SYGSGGGGGGGRGSYGSGG---SSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGG 594

Query: 67  GHKSISVSVAGGALLGRALGGFGFGSRAFMGQG 99
           G  S     +GG   G ++GG G  S      G
Sbjct: 595 GGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSG 627



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 6/94 (6%)

Query: 25  SGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGS-RSLYNLGGHKSISVSVAGGALLGR 83
           SG  A     SV+ S ++ SGGG+  G G GG+GS  S Y  GG    S    GG     
Sbjct: 494 SGECAPNVSVSVSTSHTTISGGGSRGG-GGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSY 552

Query: 84  ALGGFGFGSRAFM----GQGAGRQTFGPACPPGG 113
             GG  +GS        G G G  ++G     GG
Sbjct: 553 GSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGG 586



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 1/72 (1%)

Query: 9   TYSTKGG-FSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGG 67
           +Y + GG + S    GG GS    S S      S G GGG+  G G+GG  S       G
Sbjct: 558 SYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRG 617

Query: 68  HKSISVSVAGGA 79
             S  V  +GG+
Sbjct: 618 SSSGGVKSSGGS 629



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 3/52 (5%)

Query: 470 TGNSTTVCGGGAASFGGGISLG-GSGGATKGGFSTNVGYSTVKGGPVSAGTS 520
           +G+S+    GG+   GGG S G GSGG + GG     G S+  GG  S+G S
Sbjct: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSS--GGVKSSGGS 629



 Score = 30.0 bits (66), Expect = 5.5
 Identities = 17/39 (43%), Positives = 20/39 (51%)

Query: 478 GGGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVS 516
           GGG  S GG  S GGS G + GG  ++ G     GG  S
Sbjct: 593 GGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSS 631


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  580 bits (1496), Expect = e-166
 Identities = 329/523 (62%), Positives = 389/523 (74%), Gaps = 26/523 (4%)

Query: 15  GFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVS 74
           GFS  SA  G G   R +FSSV++S     GG   C   +GGFGSRSLYNL G+KSIS+S
Sbjct: 88  GFSCGSAIVGGGK--RGAFSSVSMS-----GGAGRCS--SGGFGSRSLYNLRGNKSISMS 138

Query: 75  VAG---GALLGRALGGFGFGS--RAFMGQGAGRQTFG-PACPPGGIQEVTVNQSLLTPLH 128
           VAG   GA  G A GGFG G     F G  +G+   G P CP GGIQEVT+NQSLLTPLH
Sbjct: 139 VAGSRQGACFGGA-GGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEVTINQSLLTPLH 197

Query: 129 VEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTR 188
           VEIDPEIQ+VRT+EREQIK LNNKFASFIDKV+FLEQQNKVLETKW LLQ+Q      + 
Sbjct: 198 VEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTT--TSS 255

Query: 189 NNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEF 248
            NLEPLFE YL  +R  LD L +++GRL SEL+ +QD VEDFK KYE+EINK TAAEN+F
Sbjct: 256 KNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDF 315

Query: 249 VVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRN 308
           VVLKKDVDAAY+ +++L  KV +L  EI+FL+ LY+ ELSQ+QTHVS+T+VVLSMDNNRN
Sbjct: 316 VVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRN 375

Query: 309 LDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRT 368
           LDLDSIIAEV+AQYE IAQRS+AEAEA YQTK ++LQ++  +HGDNL++TK+EIAEL R 
Sbjct: 376 LDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRM 435

Query: 369 IQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRD 428
           IQRL+ E +  KKQCQ LQ ++A+AEQRGE ALKDA  K  +L+ AL QAKE+L R+LR+
Sbjct: 436 IQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLRE 495

Query: 429 YQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGGGI 488
           YQELM+VKLALD+EIATYRKLLE EE RMSGEC SAVSISV   ST+  G       GG+
Sbjct: 496 YQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGG-----ISGGL 550

Query: 489 SLGGSGGATKGGFSTNVGYSTVKGGPVSAGTS--ILRKTTTVK 529
              GSG     GF +  G     GG VS  +S  I+  TT  K
Sbjct: 551 G-SGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTLNK 592


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  566 bits (1459), Expect = e-161
 Identities = 313/536 (58%), Positives = 388/536 (72%), Gaps = 37/536 (6%)

Query: 3   SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSL 62
           SS+SR+ YST     S+SA  G GS A     SV  +R    GGG   G    GFGSRSL
Sbjct: 12  SSMSRRVYST-----SSSAGSGGGSPA---VGSVCYARGRCGGGGY--GIHGRGFGSRSL 61

Query: 63  YNLGGHKSISVSVAG----GALLGRALGGFG--------------FGSRAFMGQGAGRQT 104
           YNLGG +SIS+++ G    G   G  +GGFG              FG   F G G G   
Sbjct: 62  YNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSN 121

Query: 105 FG-----PACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDK 159
           FG     P CPPGGIQEVT+NQSLL PLH+E+DPEIQR++TQEREQI  LNNKFASFIDK
Sbjct: 122 FGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDK 181

Query: 160 VRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSE 219
           VRFLEQQN+VL+TKW LLQ+   + G   NNLEPL E Y+G +R  +D L +E+ R ++E
Sbjct: 182 VRFLEQQNQVLQTKWELLQQVNTSTGT--NNLEPLLENYIGDLRRQVDLLSAEQMRQNAE 239

Query: 220 LRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFL 279
           +R++QD+VED+K+KYEDEINK T +EN+FVVLKKDVDAAY+ ++DL  +V TLT E++FL
Sbjct: 240 VRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFL 299

Query: 280 QQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQT 339
           + L+  ELSQVQTH+S+TNV+LSMDNNR+LDLDSII  V+ QYELIAQRS+ EAEA YQT
Sbjct: 300 KYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQT 359

Query: 340 KYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGEL 399
           KY+ELQ+TAG+HGD+L+++K EIAEL RT+QRLQ E    KKQ +Q+Q+ I++AE+RGE 
Sbjct: 360 KYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQ 419

Query: 400 ALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSG 459
           AL+DA +KL DL+ AL Q+KE+L RLLRDYQ ++ VKL+LDVEIATYR+LLE EESRMSG
Sbjct: 420 ALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSG 479

Query: 460 ECPSAVSISVTGNSTTVCG--GGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGG 513
           E  S VSISV  +  +V G  GG  S+G G   GGSGG   GG S   G +  + G
Sbjct: 480 ELQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSG 535



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 31/87 (35%), Positives = 40/87 (45%), Gaps = 8/87 (9%)

Query: 22  SGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVSVAGGALL 81
           SG   S    S  +  VS + G+GGG   G  +GG+G  S    GG +    S  GG   
Sbjct: 478 SGELQSHVSISVQNSQVSVNGGAGGGGSYG--SGGYGGGSGGGYGGGR----SYRGGGAR 531

Query: 82  GRALGGFGFGSRAFMGQ--GAGRQTFG 106
           GR+ GG+G G     G   G+GR   G
Sbjct: 532 GRSGGGYGSGCGGGGGSYGGSGRSGRG 558


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  563 bits (1450), Expect = e-160
 Identities = 338/574 (58%), Positives = 388/574 (67%), Gaps = 55/574 (9%)

Query: 13  KGGFSSNSASGGSGSQARTSFSS--VTVSRSSGSGGGAHCG--PGTGGFGSRSLYNLGGH 68
           K  FS  S  G SG  A  S SS    V+RS G+GGGA CG   G G FGSRSLYNLG +
Sbjct: 7   KKSFSGRS-QGFSGRSAVVSGSSRMSCVARSGGAGGGA-CGFRSGAGSFGSRSLYNLGSN 64

Query: 69  KSISVSVA----------------------GGALLGRALGGFG--------FGSR----- 93
           KSIS+SVA                      GG   G   GGFG        FG       
Sbjct: 65  KSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGG 124

Query: 94  --------AFMGQGA--GRQTFGPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQER 143
                    F G G+  G   FGP   PGGIQEV VNQSLL PL+VEIDP+I +V+ QER
Sbjct: 125 AGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQER 184

Query: 144 EQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMR 203
           EQIKTLNNKFASFIDKVRFLEQQNKVLETKW LLQ+  Q  G   ++LEP FE+Y+  + 
Sbjct: 185 EQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQ--QTTGSGPSSLEPCFESYISFLC 242

Query: 204 STLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRM 263
             LD L  ERG L+ EL+++QDLVEDFK KYEDEINK TAAENEFV LKKDVDAA+M ++
Sbjct: 243 KQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKV 302

Query: 264 DLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYE 323
           +L  KV +LT E+ FL+ LYEMELSQ+Q+H S+T+VVLSMDNNR LDL SIIAEV+AQYE
Sbjct: 303 ELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYE 362

Query: 324 LIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQC 383
            IAQRS++EAEA YQTK  ELQ TAG+HGD+LR+TK+EI EL R IQRL+ E +  KKQ 
Sbjct: 363 EIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQN 422

Query: 384 QQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEI 443
             LQTAIAEAEQRGE+ALKDA  KL DL  AL +AK+DL RLLRDYQELMNVKLALDVEI
Sbjct: 423 ANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEI 482

Query: 444 ATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFG--GGISLGGSGGATKGGF 501
           ATYRKLLE EE RMSGEC SAV ISV  N T+  G   +S G  GG+S  GSGG   G  
Sbjct: 483 ATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSS 542

Query: 502 STNVGYSTVKGGPVSAGTSILRKTTTVKTSSQRY 535
           S++     V GG  S    +   +T  + SS  Y
Sbjct: 543 SSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSY 576



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 40/103 (38%), Positives = 51/103 (49%), Gaps = 13/103 (12%)

Query: 3   SSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVT---VSRSSGSGGGAHCGPGTGGFGS 59
           +S S  + S++G F   S SG  G +  +S SS +   VS  SGSG G      TGG GS
Sbjct: 513 TSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGS 572

Query: 60  RSLY-------NLGGHKSISVSVAG-GALLG--RALGGFGFGS 92
              Y        LGG  SISVS +G G+  G  +  GG G+ S
Sbjct: 573 SGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKS 615



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 33/103 (32%), Positives = 41/103 (39%), Gaps = 20/103 (19%)

Query: 20  SASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVSVAGGA 79
           S SG SGS +R  F  V     SGSG G +     GG  S S    G        V+GG+
Sbjct: 514 STSGSSGS-SRGVFGGV-----SGSGSGGY----KGGSSSSSSSGYG--------VSGGS 555

Query: 80  LLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQEVTVNQS 122
             G   GG   GS    G     Q+       GG   ++V+ S
Sbjct: 556 --GSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHS 596


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  555 bits (1429), Expect = e-158
 Identities = 319/553 (57%), Positives = 376/553 (67%), Gaps = 56/553 (10%)

Query: 15  GFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVS 74
           GFSS SA    GS+  TS  S  +SR  G GGG     G GGFGSRSL  LGG KSIS+S
Sbjct: 21  GFSSGSAVVSGGSRRSTSSFSC-LSRHGGGGGGF----GGGGFGSRSLVGLGGTKSISIS 75

Query: 75  VAGGA---------------------------LLGRALGGFGFGSRAFMGQGA------- 100
           VAGG                              G   GG GFG   F G G        
Sbjct: 76  VAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGL 135

Query: 101 -GRQTFGPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDK 159
            G   FGP   PGGI EV+VNQSLL PL+V++DPEIQ V+ QEREQIKTLNNKFASFIDK
Sbjct: 136 GGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDK 195

Query: 160 VRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSE 219
           VRFLEQQN+VL+TKW LLQ+   N+G    NLEP+F+ Y+ S++  LD L +ER   +SE
Sbjct: 196 VRFLEQQNQVLQTKWELLQQM--NVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSE 253

Query: 220 LRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFL 279
           L N+QDLVED+K KYEDEINK TAAEN+FV LKKDVD AYM +++L  KV  L QEI+FL
Sbjct: 254 LNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFL 313

Query: 280 QQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQT 339
           + LY+ E+SQ+   V++TNV+LSMDN+RNLDLDSIIAEVKAQYE IAQRS+ EAEA Y +
Sbjct: 314 KVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHS 373

Query: 340 KYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGEL 399
           KYEELQVT G+HGD+L++ K EI+EL R IQRLQGE    KKQC+ +Q AIA+AEQRGE 
Sbjct: 374 KYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEH 433

Query: 400 ALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSG 459
           ALKDA+ KL DL+ AL QAKEDL RLLRDYQELMNVKLALDVEIATYRKLLE EE RMSG
Sbjct: 434 ALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSG 493

Query: 460 ECPSAVSISVTGNSTTV----------CGGGAASFGGGISLG----GSGGATKGGFSTNV 505
           +  S V++SVT ++ +            GG  +S GGG S G    GSGG   G    + 
Sbjct: 494 DLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSG 553

Query: 506 GYSTVKGGPVSAG 518
           G  ++ GG   +G
Sbjct: 554 GGGSISGGGYGSG 566



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 33/92 (35%), Positives = 39/92 (42%), Gaps = 8/92 (8%)

Query: 11  STKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTG-GFGSRSLYNLGGHK 69
           S+ GG+SS S+S GSG +        + SR    GGG+  G G G G GS   Y  GG  
Sbjct: 527 SSGGGYSSGSSSYGSGGRQ-------SGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGS 579

Query: 70  SISVSVAGGALLGRALGGFGFGSRAFMGQGAG 101
                  GG   G      G GSR     G G
Sbjct: 580 KGGSISGGGYGSGGGKHSSGGGSRGGSSSGGG 611



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 25/74 (33%), Positives = 29/74 (39%), Gaps = 2/74 (2%)

Query: 14  GGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPG--TGGFGSRSLYNLGGHKSI 71
           GG+ S   SGG       S          GSGGG H   G   GG  S   Y  GG  S 
Sbjct: 561 GGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSS 620

Query: 72  SVSVAGGALLGRAL 85
           SV  + G   G ++
Sbjct: 621 SVKGSSGEAFGSSV 634



 Score = 32.7 bits (73), Expect = 0.85
 Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 3/58 (5%)

Query: 10  YSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGG 67
           Y + GG    S SGG         SS   SR   S GG   G G+GG GS S+    G
Sbjct: 573 YGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGG---GYGSGGGGSSSVKGSSG 627


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  538 bits (1385), Expect = e-153
 Identities = 291/501 (58%), Positives = 370/501 (73%), Gaps = 18/501 (3%)

Query: 25  SGSQARTSFSSVTVSRSSGSGGGAHCGPG--TGGFGSRSLYNLGGHKSISVSVAGGALLG 82
           SG+ A+  FS  +   S GS      G    +GGF SRSLY+LGG +SIS +VA G+  G
Sbjct: 9   SGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGS--G 66

Query: 83  RALGGFGFG---SRAFMGQGAGRQTFGPACP----PGGIQEVTVNQSLLTPLHVEIDPEI 135
            A GG+GFG   +  F G   G    G  CP    PGGI +VT+N+SLL PL+VE+DPEI
Sbjct: 67  WA-GGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEI 125

Query: 136 QRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLF 195
           Q+VR QEREQIK LNNKFASFIDKVRFLEQQN+VLETKW LLQ+   +L   +NNLEP+ 
Sbjct: 126 QKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQL--DLNNCKNNLEPIL 183

Query: 196 EAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDV 255
           E Y+ ++R  L+ L  +R RLDSELR+V+++VED+K +YE+EINK T AENEFVVLKKDV
Sbjct: 184 EGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDV 243

Query: 256 DAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSII 315
           DAAY  +++L  KV  L  EI F + LYE E +Q+Q+H+S+T+++LSMDNNRNLDLDSII
Sbjct: 244 DAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSII 303

Query: 316 AEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGE 375
           AEV+AQYE IA++S+AEAEA YQTK++ELQ+ AG+HGD+L+ TKNEI+ELTR IQRL+ E
Sbjct: 304 AEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSE 363

Query: 376 ADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNV 435
            ++ KKQC  L+TAIA+AEQRG+ ALKDA+ KL +L+ AL QAKE+L R+LR+YQEL++V
Sbjct: 364 IESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSV 423

Query: 436 KLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGGGISLGGSGG 495
           KL+LD+EIATYRKLLE EE RMSGE  ++VSISV  +S      G A  G G     +G 
Sbjct: 424 KLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSM----AGMAGTGAGFGFSNAGT 479

Query: 496 ATKGGFSTNVGYSTVKGGPVS 516
                 S + GYS + GG V+
Sbjct: 480 YGYWPSSVSGGYSMLPGGCVT 500


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  535 bits (1379), Expect = e-152
 Identities = 294/518 (56%), Positives = 377/518 (72%), Gaps = 23/518 (4%)

Query: 25  SGSQARTSFSSVTVSRSSGSGGGAHCGPG--TGGFGSRSLYNLGGHKSISVSVAGGALLG 82
           SG+ A+  FS  +   S GS      G    +GGFGSRSLY+LGG +S++V+   G    
Sbjct: 9   SGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGKS-- 66

Query: 83  RALGGFGFG---SRAFMGQGAGRQTFGPACP----PGGIQEVTVNQSLLTPLHVEIDPEI 135
              GG+GFG   +  F G   G    GP CP    PGGI +VTVN+SLL PL+VE+DPEI
Sbjct: 67  ---GGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEI 123

Query: 136 QRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLF 195
           Q+VR QEREQIK LNNKFASFIDKVRFLEQQN+VLETKW LLQ+   +L   +NNLEP+ 
Sbjct: 124 QKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQL--DLNNCKNNLEPIL 181

Query: 196 EAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDV 255
           E Y+ ++R  L+ L  +R RLDSELRNV+D+VED+K +YE+EINK TAAENEFV+LKKDV
Sbjct: 182 EGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDV 241

Query: 256 DAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSII 315
           DAAY  +++L  KV ++ QEI F + L+E E++Q+Q+H+S+ +V+LSMDNNRNLDLDSII
Sbjct: 242 DAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSII 301

Query: 316 AEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGE 375
            EV+ QYE IA +S+AEAEA YQTK++ELQ+ AG+HGD+L++TKNEI+ELTR IQR++ E
Sbjct: 302 DEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSE 361

Query: 376 ADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNV 435
            +  KKQ   L+TAIA+AEQRG+ ALKDA+ KL +L+ ALHQAKE+L R+LR+YQELM++
Sbjct: 362 IENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSL 421

Query: 436 KLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGGGISLGGSGG 495
           KLALD+EIATYRKLLESEE RMSGE PS VSIS+  +++   GG    F   +    SGG
Sbjct: 422 KLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTS---GGSVYGFRPSMV---SGG 475

Query: 496 ATKGGFSTNVGYSTVKGGP-VSAGTSILRKTTTVKTSS 532
                 +   G  +V+GG   S G++   K T  K SS
Sbjct: 476 YVANSSNCISGVCSVRGGEGRSRGSANDYKDTLGKGSS 513


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  518 bits (1335), Expect = e-147
 Identities = 291/494 (58%), Positives = 364/494 (73%), Gaps = 33/494 (6%)

Query: 5   VSRQ-TYSTKG---GFSSNSA--SGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFG 58
           +SRQ T+  +G   GFS  SA  SGG GS + +  + V                G+  FG
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVK---------------GSASFG 45

Query: 59  SRSLYNLGGHKSISVSVA---GGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQ 115
           S+SL  LGG +S+++S A   GG  LG      GF   AF   G G +     CPPGGI 
Sbjct: 46  SKSLSCLGGSRSLALSAAARRGGGRLG------GFVGTAFGSAGLGPKC-PSVCPPGGIP 98

Query: 116 EVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWA 175
           +VTVN+SLL PL+VE+DPEIQRVR QEREQIK LNNKFASFIDKVRFLEQQN+VLETKW 
Sbjct: 99  QVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWN 158

Query: 176 LLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYE 235
           LLQ+   +L   R NLEP++E Y+ +++  L+ L  +  RLDSELRN+QDLVED+K +YE
Sbjct: 159 LLQQL--DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216

Query: 236 DEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVS 295
            EIN+ TAAENEFVVLKKDVDAAYM +++L  KV +LT EI F + LYE E++Q+Q+H+S
Sbjct: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276

Query: 296 NTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNL 355
           +T++VLSMDNNR+LDLDSIIAEV+AQYE IA +S+AEAE  YQTK +ELQVTAG+HGD+L
Sbjct: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDL 336

Query: 356 RDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVAL 415
           + TK EI+EL R IQR++ E    KKQC  L+TAIA+AEQRG+ ALKDA+ KL +L+ AL
Sbjct: 337 KLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGAL 396

Query: 416 HQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTT 475
           HQAKE+L R+LR+YQEL+++KLALD+EIATYRKLLESEE RMSGE P++VSISV  ++  
Sbjct: 397 HQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA 456

Query: 476 VCGGGAASFGGGIS 489
             GG   S G G S
Sbjct: 457 GAGGAGFSMGFGAS 470


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  518 bits (1335), Expect = e-147
 Identities = 291/494 (58%), Positives = 364/494 (73%), Gaps = 33/494 (6%)

Query: 5   VSRQ-TYSTKG---GFSSNSA--SGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFG 58
           +SRQ T+  +G   GFS  SA  SGG GS + +  + V                G+  FG
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVK---------------GSASFG 45

Query: 59  SRSLYNLGGHKSISVSVA---GGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQ 115
           S+SL  LGG +S+++S A   GG  LG      GF   AF   G G +     CPPGGI 
Sbjct: 46  SKSLSCLGGSRSLALSAAARRGGGRLG------GFVGTAFGSAGLGPKC-PSVCPPGGIP 98

Query: 116 EVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWA 175
           +VTVN+SLL PL+VE+DPEIQRVR QEREQIK LNNKFASFIDKVRFLEQQN+VLETKW 
Sbjct: 99  QVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWN 158

Query: 176 LLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYE 235
           LLQ+   +L   R NLEP++E Y+ +++  L+ L  +  RLDSELRN+QDLVED+K +YE
Sbjct: 159 LLQQL--DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216

Query: 236 DEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVS 295
            EIN+ TAAENEFVVLKKDVDAAYM +++L  KV +LT EI F + LYE E++Q+Q+H+S
Sbjct: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276

Query: 296 NTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNL 355
           +T++VLSMDNNR+LDLDSIIAEV+AQYE IA +S+AEAE  YQTK +ELQVTAG+HGD+L
Sbjct: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDL 336

Query: 356 RDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVAL 415
           + TK EI+EL R IQR++ E    KKQC  L+TAIA+AEQRG+ ALKDA+ KL +L+ AL
Sbjct: 337 KLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGAL 396

Query: 416 HQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTT 475
           HQAKE+L R+LR+YQEL+++KLALD+EIATYRKLLESEE RMSGE P++VSISV  ++  
Sbjct: 397 HQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA 456

Query: 476 VCGGGAASFGGGIS 489
             GG   S G G S
Sbjct: 457 GAGGAGFSMGFGAS 470


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  514 bits (1325), Expect = e-146
 Identities = 284/494 (57%), Positives = 359/494 (72%), Gaps = 23/494 (4%)

Query: 25  SGSQARTSFSSVTVSRSSGSGGGAHCGPGTG---GFGSRSLYNLGGHKSISVSVAGGALL 81
           SG +   S  S  V R +     ++C  G G   GFGSRSLY+LGG++ IS +VAGG   
Sbjct: 10  SGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGG--- 66

Query: 82  GRALGGFGF-------GSRA--FMGQGAGRQTFGPAC----PPGGIQEVTVNQSLLTPLH 128
           G   GG+GF       G RA  F G   G    GPAC    PPGGI +VTVN+SLL PL+
Sbjct: 67  GVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLN 126

Query: 129 VEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTR 188
           VE+DPEIQ+VR QEREQIK LN+KFASFIDKVRFLEQQN+VLETKW LLQ+   +L   +
Sbjct: 127 VELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQL--DLNNCK 184

Query: 189 NNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEF 248
            NLEP+ E Y+ ++R  L+ L  +R RLDSELR+++DLVED+K +YE EIN+ T AENEF
Sbjct: 185 KNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEF 244

Query: 249 VVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRN 308
           VVLKKD DAAY  +++L  KV +L +EI FL+ LY+ E++Q+QTH S T+V+LSMDNNR+
Sbjct: 245 VVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRD 304

Query: 309 LDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRT 368
           LDLDSIIAEV+  YE IA +S+AEAEA YQTK +ELQ+ A +HGD+L+ T++E+ EL R 
Sbjct: 305 LDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRL 364

Query: 369 IQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRD 428
           IQR++ E    KKQ   L+TAIA+AEQRG+ ALKDAQ KL +L+ ALHQAKE+L R+LR+
Sbjct: 365 IQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLRE 424

Query: 429 YQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVC--GGGAASFGG 486
           YQELM++KLALD+EIATYRKLLE EE RMSGE PS+VSISV  +S+        A    G
Sbjct: 425 YQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLG 484

Query: 487 GISLGGSGGATKGG 500
             ++ GS G+T+ G
Sbjct: 485 ASAVAGSSGSTQSG 498


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  479 bits (1234), Expect = e-135
 Identities = 274/496 (55%), Positives = 348/496 (70%), Gaps = 43/496 (8%)

Query: 34  SSVTVSRSSG-SGGGAHCGPGT---GGFGSRSLYNLGGHKS-ISVSVAGGALLGRALGGF 88
           S V  SRS+  SG GA     +   GG GS SLY LG  +  ++V  A G  +G      
Sbjct: 7   SPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVG------ 60

Query: 89  GFGSRAFMGQGAGRQTFGPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKT 148
                                   GI+EVT+NQSLL PL ++ DP +QRVR +E EQIKT
Sbjct: 61  -----------------------AGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKT 97

Query: 149 LNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDR 208
           LNNKFASFIDKVRFLEQQNK+LETKW LLQEQ        + L  +FEA +  +R  L+ 
Sbjct: 98  LNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKS---AKSSRLPDIFEAQIAGLRGQLEA 154

Query: 209 LQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGK 268
           LQ + GRL++ELR++QD+VEDFKNKYEDEIN  TAAENEFVVLKKDVDAAYM +++L  K
Sbjct: 155 LQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAK 214

Query: 269 VGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQR 328
           V  L  EI+FL+ L E EL+++Q+ +S+T+VVLSMDN+R+LDLD IIAEVKAQYE +A+ 
Sbjct: 215 VDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKC 274

Query: 329 SRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQT 388
           SRAEAEAWYQTK+E LQ  AGKHGD+LR+T+NEI+E+ R IQRLQ E D  K Q  +L+ 
Sbjct: 275 SRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEA 334

Query: 389 AIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRK 448
           AIAEAE+RGELALKDA+ K  +L+ AL + K+D+ R LR+YQELM+VKLALD+EIATYRK
Sbjct: 335 AIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRK 394

Query: 449 LLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGG-GISLGGSGGATKGGFSTNVGY 507
           LLE EESR++G+   AV+ISV  NST    GG++S GG G++LGG+ G+    FS++ G 
Sbjct: 395 LLEGEESRLAGDGVGAVNISVM-NST----GGSSSGGGIGLTLGGTMGSNALSFSSSAGP 449

Query: 508 STVKGGPVSAGTSILR 523
             +K   +   ++  R
Sbjct: 450 GLLKAYSIRTASASRR 465


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  464 bits (1194), Expect = e-131
 Identities = 268/504 (53%), Positives = 346/504 (68%), Gaps = 33/504 (6%)

Query: 51  GPGTGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFGPA-- 108
           G   GGF SR     GG  S S++  GG L G     +G G R  +G   G  + GP   
Sbjct: 24  GRSRGGFSSR-----GGFSSRSLNSFGGCLEGSRGSTWGSGGR--LGVRFGEWSGGPGLS 76

Query: 109 -CPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQN 167
            CPPGGIQEVT+NQ+LLTPL +EIDP+ Q VRTQE ++I+TLNN+FASFIDKVRFLEQQN
Sbjct: 77  LCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQN 136

Query: 168 KVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLV 227
           KVLETKW LLQ+QG  L  ++  LEP+FEA L  +R  L++LQ ERG LD+EL+  +D  
Sbjct: 137 KVLETKWHLLQQQG--LSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQE 194

Query: 228 EDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMEL 287
           E++K+KYE+E ++    EN+FVVLKKDVD  ++ +M+L GK+  L + + FL+ L E EL
Sbjct: 195 EEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEEL 254

Query: 288 SQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVT 347
            Q+QT  S+T+VVLSMDNNR LD  SII EV+A+YE IA+ S+AEAEA YQTKY+ELQV+
Sbjct: 255 GQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVS 314

Query: 348 AGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKK 407
           A  HGD +++TK +I++L + IQRLQ + +  KKQ   LQ AI +AEQRGELALKDAQ K
Sbjct: 315 AQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAK 374

Query: 408 LGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSI 467
           + +L+ AL  AK++L RLL +YQEL + KL+LDVEIATYR+LLE EE RMSGEC S V+I
Sbjct: 375 VDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTI 434

Query: 468 SVTGNSTTVCGGGAASFGGGISLGGSGGATKGGFSTNV---GYSTVKGG---PV------ 515
           S  G S  + GG     G    L GSG  + G   T++   G + + G    PV      
Sbjct: 435 SSVGGSAVMSGGVGGGLGSTCGL-GSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSV 493

Query: 516 ---SAGTS---ILRKT--TTVKTS 531
              SAG+S   IL+KT  +++KTS
Sbjct: 494 SGSSAGSSCHTILKKTVESSLKTS 517


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  460 bits (1183), Expect = e-129
 Identities = 254/457 (55%), Positives = 322/457 (70%), Gaps = 21/457 (4%)

Query: 53  GTGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPG 112
           G   F SRS Y  G    IS S           GG G G             +G A   G
Sbjct: 16  GPRAFSSRS-YTSGPGSRISSSSFSRVGSSNFRGGLGGG-------------YGGASGMG 61

Query: 113 GIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLET 172
           GI  VTVNQSLL+PL +E+DP IQ VRTQE+EQIKTLNNKFASFIDKVRFLEQQNK+LET
Sbjct: 62  GITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLET 121

Query: 173 KWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKN 232
           KW+LLQ+Q       R+N++ +FE+Y+ ++R  L+ L  E+ +L++EL N+Q LVEDFKN
Sbjct: 122 KWSLLQQQK----TARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKN 177

Query: 233 KYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQT 292
           KYEDEINK T  ENEFV++KKDVD AYM +++L  ++  LT EI+FL+QLYE E+ ++Q+
Sbjct: 178 KYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQS 237

Query: 293 HVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHG 352
            +S+T+VVLSMDN+R+LD+DSIIAEVKAQYE IA RSRAEAE+ YQ KYEELQ  AGKHG
Sbjct: 238 QISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHG 297

Query: 353 DNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLD 412
           D+LR TK EI+E+ R I RLQ E +  K Q   L+ AIA+AEQRGELA+KDA  KL +L+
Sbjct: 298 DDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELE 357

Query: 413 VALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGN 472
            AL +AK+D+ R LR+YQELMNVKLALD+EIATYRKLLE EESR+        ++S+   
Sbjct: 358 AALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLES---GMQNMSIHTK 414

Query: 473 STTVCGGGAASFGGGISLGGSGGATKGGFSTNVGYST 509
           +T+   GG +S  GG++  G   +    F +  G S+
Sbjct: 415 TTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGSSS 451


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  458 bits (1179), Expect = e-129
 Identities = 280/553 (50%), Positives = 349/553 (63%), Gaps = 55/553 (9%)

Query: 14  GGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLG------- 66
           G FSS SA      Q    F + +VS  SG G       G G FGSRS+   G       
Sbjct: 15  GNFSSCSAMT---PQNLNRFRANSVSCWSGPGFR-----GLGSFGSRSVITFGSYSPRIA 66

Query: 67  --GHKSISVSVAGGALLGRALG---------------GFGFGSRAFMGQGAGRQTFG--- 106
             G + I   V  GA  G   G               G GFG+ + +G G G   FG   
Sbjct: 67  AVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRV 126

Query: 107 -----PACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVR 161
                PA P   I  VTVN+SLLTPL++EIDP  QRV+  E+EQIKTLNNKFASFIDKVR
Sbjct: 127 GGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVR 184

Query: 162 FLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELR 221
           FLEQQNK+LETKW+ LQEQ       R+NLEPLFE+Y+ ++R  L+ L S++ RL +E  
Sbjct: 185 FLEQQNKLLETKWSFLQEQK----CIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERN 240

Query: 222 NVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQ 281
           ++QD++E FK KYE+E+     AENEFV LKKDVDAA+M + DL   V TLTQEIDFL+ 
Sbjct: 241 HLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKT 300

Query: 282 LYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKY 341
           LY  E+  +Q+H+S T+V++ MDN+R+L+LD IIAEVKAQYE +A+RSRA+AEAWYQTKY
Sbjct: 301 LYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKY 360

Query: 342 EELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELAL 401
           EE+QVTAG+H DNLR+ +NEI ELTR IQRL+ E + AK Q  +L+ A+AEAEQ+GE  L
Sbjct: 361 EEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATL 420

Query: 402 KDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRM-SGE 460
            DA+ KL DL+ AL QAK+D+ R L +YQELMN KL LD+EIATYR+LLE EESR+  G 
Sbjct: 421 SDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGV 480

Query: 461 CPSAVSISVTGNSTTVCG------GGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGGP 514
            P  +S+S +     VCG      G   S GG    G S      G   + G S + G  
Sbjct: 481 GPVNISVS-SSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPS-LGGAR 538

Query: 515 VSAGTSILRKTTT 527
           V+  T  L  T T
Sbjct: 539 VAPATGDLLSTGT 551


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  451 bits (1160), Expect = e-127
 Identities = 266/494 (53%), Positives = 332/494 (67%), Gaps = 75/494 (15%)

Query: 5   VSRQ-TYSTKG---GFSSNSA--SGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFG 58
           +SRQ T+  +G   GFS  SA  SGG GS + +  + V                G+  FG
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVK---------------GSASFG 45

Query: 59  SRSLYNLGGHKSISVSVA---GGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQ 115
           S+SL  LGG +S+++S A   GG  LG      GF   AF   G G +     CPPGGI 
Sbjct: 46  SKSLSCLGGSRSLALSAAARRGGGRLG------GFVGTAFGSAGLGPKC-PSVCPPGGIP 98

Query: 116 EVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWA 175
           +VTVN+SLL PL+VE+DPEIQRVR QEREQIK LNNKFASFIDKVRFLEQQN+VLETKW 
Sbjct: 99  QVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWN 158

Query: 176 LLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYE 235
           LLQ+   +L   R NLEP++E Y+ +++  L+ L  +  RLDSELRN+QDLVED+K +YE
Sbjct: 159 LLQQL--DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216

Query: 236 DEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVS 295
            EIN+ TAAENEFVVLKKDVDAAYM +++L  KV +LT EI F + LYE E++Q+Q+H+S
Sbjct: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276

Query: 296 NTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNL 355
           +T++VLSMDNNR+LDLDSIIAEV+AQYE IA +S+AEAE  YQTK               
Sbjct: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK--------------- 321

Query: 356 RDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVAL 415
                                      C  L+TAIA+AEQRG+ ALKDA+ KL +L+ AL
Sbjct: 322 ---------------------------CADLETAIADAEQRGDCALKDARAKLDELEGAL 354

Query: 416 HQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTT 475
           HQAKE+L R+LR+YQEL+++KLALD+EIATYRKLLESEE RMSGE P++VSISV  ++  
Sbjct: 355 HQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA 414

Query: 476 VCGGGAASFGGGIS 489
             GG   S G G S
Sbjct: 415 GAGGAGFSMGFGAS 428


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  410 bits (1054), Expect = e-114
 Identities = 237/488 (48%), Positives = 313/488 (64%), Gaps = 41/488 (8%)

Query: 26  GSQARTSFSSV--------TVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVSVAG 77
           GSQ+ +S+S+V         VS+     GG       G  GSRSL N+G  +    S  G
Sbjct: 13  GSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNVGFGRPRVASRCG 72

Query: 78  GALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGG-IQEVTVNQSLLTPLHVEIDPEIQ 136
           G L G       FG R            G  C P   I  VT+N+SLL PL +EIDP +Q
Sbjct: 73  GTLPG-------FGYR-----------LGATCGPSACITPVTINESLLVPLALEIDPTVQ 114

Query: 137 RVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFE 196
           RV+  E+EQIK LNN+FASFI+KVRFLEQ+NK+LETKW  +Q+Q       + N+EP+FE
Sbjct: 115 RVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQR----CCQTNIEPIFE 170

Query: 197 AYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVD 256
            Y+ ++R  LD +  +R RL+SEL ++Q  +E +K KYE+E++     ENEFV LKKDVD
Sbjct: 171 GYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVD 230

Query: 257 AAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIA 316
            A++ + DL      L QEIDFL+ LYE E+  +Q+ +S T+V++ MDN+R LD+D IIA
Sbjct: 231 TAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIA 290

Query: 317 EVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEA 376
           E+KAQY+ IA RS+AEAEAWYQ +YEEL+VTAG H DNLR+ KNEI E+ + IQRLQ E 
Sbjct: 291 EIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQET 350

Query: 377 DAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVK 436
           +  K Q  +L+ AIAEAEQ+GE AL DA+ KL  L+ AL +AK+D+  LL++YQE+MN K
Sbjct: 351 ENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSK 410

Query: 437 LALDVEIATYRKLLESEESRM-SGECPSAVSISVT---------GNSTTVCGGGAASFGG 486
           L LD+EIATYR+LLE EE R+  G  P  +S+S +         G ST V   G     G
Sbjct: 411 LGLDIEIATYRRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNG 470

Query: 487 GISLGGSG 494
           G S+ G+G
Sbjct: 471 GCSIVGTG 478


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  407 bits (1045), Expect = e-113
 Identities = 231/483 (47%), Positives = 318/483 (65%), Gaps = 44/483 (9%)

Query: 47  GAHCGPGTGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFG 106
           G  C  G  GFGSRSL NLG          G  +   A+GGF  GS    G+  G ++ G
Sbjct: 41  GVSCYRGLTGFGSRSLCNLGS--------CGPRI---AVGGFRAGS---CGRSFGYRSGG 86

Query: 107 PACP-PGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165
              P P  I  V+VN+SLLTPL++EIDP  Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 87  VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 146

Query: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225
           QNK+LETKW   Q Q        +NLEPLF  Y+ ++R   + ++++ GRL SEL +VQ+
Sbjct: 147 QNKLLETKWQFYQNQR----CCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQE 202

Query: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285
           ++E +K KYE+E+     AENEFVVLKKDVD AY+ + DL   V  L +E  FL++LYE 
Sbjct: 203 VLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEE 262

Query: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345
           E+  +Q H+S+T+V++ MDN+R+L++D IIAE+KAQY+ +A RSRAEAE+WY++K EE++
Sbjct: 263 EIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMK 322

Query: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405
            T  +HG+ LR TK EI EL R IQRL  E + AK Q  +L+ A+AEAEQ+GE AL DA+
Sbjct: 323 ATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDAR 382

Query: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465
            KL +L+ AL +AK+D+  LL++YQE+MN KL LD+EIATYR+LLE EE R+   C    
Sbjct: 383 CKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL---CEGVG 439

Query: 466 SISVTGNSTTVCGGGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVSAGTSILRKT 525
           S++V  +S+           GG+S GG            + YST  G  +++G S +  +
Sbjct: 440 SVNVCVSSSR----------GGVSCGG------------LSYSTTPGRQITSGPSAIGGS 477

Query: 526 TTV 528
            TV
Sbjct: 478 ITV 480


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  389 bits (999), Expect = e-108
 Identities = 218/441 (49%), Positives = 297/441 (67%), Gaps = 35/441 (7%)

Query: 47  GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105
           G  C  G TGGFGS S             V GG   G     FG+ S    G        
Sbjct: 34  GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 74

Query: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165
            P C    I  V+VN+SLLTPL++EIDP  Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 75  -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 129

Query: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225
           QNK+LETK    Q    N    ++NLEPLFE Y+ ++R   + ++++ GRL SEL +VQ+
Sbjct: 130 QNKLLETKLQFYQ----NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185

Query: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285
           ++E +K KYE+E++    AENEFV LKKDVD AY+ + DL   V  L QEIDFL++LYE 
Sbjct: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245

Query: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345
           E+  +Q+H+S+T+VV+ +DN+R+L++D IIAE+KAQY+ I  RSRAEAE+WY++K EE++
Sbjct: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305

Query: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405
            T  +HG+ LR TK EI EL R IQRL  E + AK Q  +L+ A+A++EQ+GE AL DA+
Sbjct: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365

Query: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465
            KL +L+ AL +AK+D+  L+R+YQE+MN KL LD+EIATYR+LLE EE R+   C    
Sbjct: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL---CEGVG 422

Query: 466 SISVTGNST---TVCGGGAAS 483
           S++V  +S+    VCG   AS
Sbjct: 423 SVNVCVSSSRGGVVCGDLCAS 443


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  389 bits (999), Expect = e-108
 Identities = 218/441 (49%), Positives = 297/441 (67%), Gaps = 35/441 (7%)

Query: 47  GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105
           G  C  G TGGFGS S             V GG   G     FG+ S    G        
Sbjct: 34  GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 74

Query: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165
            P C    I  V+VN+SLLTPL++EIDP  Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 75  -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 129

Query: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225
           QNK+LETK    Q    N    ++NLEPLFE Y+ ++R   + ++++ GRL SEL +VQ+
Sbjct: 130 QNKLLETKLQFYQ----NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185

Query: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285
           ++E +K KYE+E++    AENEFV LKKDVD AY+ + DL   V  L QEIDFL++LYE 
Sbjct: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245

Query: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345
           E+  +Q+H+S+T+VV+ +DN+R+L++D IIAE+KAQY+ I  RSRAEAE+WY++K EE++
Sbjct: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305

Query: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405
            T  +HG+ LR TK EI EL R IQRL  E + AK Q  +L+ A+A++EQ+GE AL DA+
Sbjct: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365

Query: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465
            KL +L+ AL +AK+D+  L+R+YQE+MN KL LD+EIATYR+LLE EE R+   C    
Sbjct: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL---CEGVG 422

Query: 466 SISVTGNST---TVCGGGAAS 483
           S++V  +S+    VCG   AS
Sbjct: 423 SVNVCVSSSRGGVVCGDLCAS 443


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  389 bits (999), Expect = e-108
 Identities = 218/441 (49%), Positives = 297/441 (67%), Gaps = 35/441 (7%)

Query: 47  GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105
           G  C  G TGGFGS S             V GG   G     FG+ S    G        
Sbjct: 34  GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 74

Query: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165
            P C    I  V+VN+SLLTPL++EIDP  Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 75  -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 129

Query: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225
           QNK+LETK    Q    N    ++NLEPLFE Y+ ++R   + ++++ GRL SEL +VQ+
Sbjct: 130 QNKLLETKLQFYQ----NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185

Query: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285
           ++E +K KYE+E++    AENEFV LKKDVD AY+ + DL   V  L QEIDFL++LYE 
Sbjct: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245

Query: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345
           E+  +Q+H+S+T+VV+ +DN+R+L++D IIAE+KAQY+ I  RSRAEAE+WY++K EE++
Sbjct: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305

Query: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405
            T  +HG+ LR TK EI EL R IQRL  E + AK Q  +L+ A+A++EQ+GE AL DA+
Sbjct: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365

Query: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465
            KL +L+ AL +AK+D+  L+R+YQE+MN KL LD+EIATYR+LLE EE R+   C    
Sbjct: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL---CEGVG 422

Query: 466 SISVTGNST---TVCGGGAAS 483
           S++V  +S+    VCG   AS
Sbjct: 423 SVNVCVSSSRGGVVCGDLCAS 443


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  389 bits (999), Expect = e-108
 Identities = 218/441 (49%), Positives = 297/441 (67%), Gaps = 35/441 (7%)

Query: 47  GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105
           G  C  G TGGFGS S             V GG   G     FG+ S    G        
Sbjct: 34  GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 74

Query: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165
            P C    I  V+VN+SLLTPL++EIDP  Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 75  -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 129

Query: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225
           QNK+LETK    Q    N    ++NLEPLFE Y+ ++R   + ++++ GRL SEL +VQ+
Sbjct: 130 QNKLLETKLQFYQ----NRECCQSNLEPLFEGYIETLRREAECVEADSGRLASELNHVQE 185

Query: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285
           ++E +K KYE+E++    AENEFV LKKDVD AY+ + DL   V  L QEIDFL++LYE 
Sbjct: 186 VLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 245

Query: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345
           E+  +Q+H+S+T+VV+ +DN+R+L++D IIAE+KAQY+ I  RSRAEAE+WY++K EE++
Sbjct: 246 EIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMK 305

Query: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405
            T  +HG+ LR TK EI EL R IQRL  E + AK Q  +L+ A+A++EQ+GE AL DA+
Sbjct: 306 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 365

Query: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465
            KL +L+ AL +AK+D+  L+R+YQE+MN KL LD+EIATYR+LLE EE R+   C    
Sbjct: 366 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRL---CEGVG 422

Query: 466 SISVTGNST---TVCGGGAAS 483
           S++V  +S+    VCG   AS
Sbjct: 423 SVNVCVSSSRGGVVCGDLCAS 443


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  388 bits (996), Expect = e-108
 Identities = 233/511 (45%), Positives = 320/511 (62%), Gaps = 39/511 (7%)

Query: 42  SGSGGGAH-----CGPGTGGFGSRSLYNLGGHKSISV--SVAGGALLGRALGGFGFGSRA 94
           SG GG A      CGP  G    R       ++ IS    + GG       GGF  GS  
Sbjct: 5   SGFGGRAFSCISACGPRPG----RCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGS-- 58

Query: 95  FMGQGAGRQTFGPACP-PGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKF 153
             G+  G ++ G   P P  I  V+VN+SLLTPL++EIDP  Q V+ +E+EQIK+LN++F
Sbjct: 59  -CGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRF 117

Query: 154 ASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSER 213
           A+FIDKVRFLEQQNK+LETK    Q    N    ++NLEPLFE Y+ ++R   + ++++ 
Sbjct: 118 AAFIDKVRFLEQQNKLLETKLQFYQ----NRECCQSNLEPLFEGYIETLRREAECVEADS 173

Query: 214 GRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLT 273
           GRL SEL +VQ+++E +K KYE+E++    AENEFV LKKDVD AY+ + DL   V  L 
Sbjct: 174 GRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALI 233

Query: 274 QEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEA 333
           QEIDFL++LYE E+  +Q+H+S+T+VV+ +DN+R+L++D IIAE+KAQY+ I  RSRAEA
Sbjct: 234 QEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEA 293

Query: 334 EAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEA 393
           E+WY++K EE++ T  +HG+ LR TK EI EL R IQRL  E + AK Q  +L+ A+A++
Sbjct: 294 ESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQS 353

Query: 394 EQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESE 453
           EQ+GE AL DA+ KL +L+ AL +AK+D+  L+R+YQE+MN KL LD+EIATYR+LLE E
Sbjct: 354 EQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGE 413

Query: 454 ESRM-------------------SGECPSAVSISVTGN-STTVCGGGAASFGGGISLGGS 493
           E R+                    G+   + S  VTG+  +  C G  A   G  +  G 
Sbjct: 414 EQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQ 473

Query: 494 GGATKGGFSTNVGYSTVKGGPVSAGTSILRK 524
              T GG S  VG   +    V +  S  RK
Sbjct: 474 LNTTCGGGSCGVGSCGISSLGVGSCGSSCRK 504


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  385 bits (988), Expect = e-107
 Identities = 215/434 (49%), Positives = 294/434 (67%), Gaps = 31/434 (7%)

Query: 47  GAHCGPG-TGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTF 105
           G  C  G TGGFGS S             V GG   G     FG+ S    G        
Sbjct: 39  GISCYRGLTGGFGSHS-------------VCGGFRAGSCGRSFGYRSGGVCGPS------ 79

Query: 106 GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQ 165
            P C    I  V+VN+SLLTPL++EIDP  Q V+ +E+EQIK+LN++FA+FIDKVRFLEQ
Sbjct: 80  -PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQ 134

Query: 166 QNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQD 225
           QNK+LETK    Q    N    ++NLEPLF  Y+ ++R   + ++++ GRL SEL +VQ+
Sbjct: 135 QNKLLETKLQFYQ----NRECCQSNLEPLFAGYIETLRREAECVEADSGRLASELNHVQE 190

Query: 226 LVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEM 285
           ++E +K KYE+E+     AENEFV LKKDVD AY+ + DL   V  L QEIDFL++LYE 
Sbjct: 191 VLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEE 250

Query: 286 ELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQ 345
           E+  +Q+H+S+T+VV+ +DN+R+L++D I+AE+KAQY+ IA RSRAEAE+WY++K EE++
Sbjct: 251 EIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMK 310

Query: 346 VTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQ 405
            T  +HG+ LR TK EI EL R IQRL  E + AK Q  +L+ A+A++EQ+GE AL DA+
Sbjct: 311 ATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDAR 370

Query: 406 KKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAV 465
            KL +L+ AL +AK+D+  L+R+YQE+MN KL LD+EIATYR+LLE EE R+  E   AV
Sbjct: 371 CKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAV 429

Query: 466 SISVTGN-STTVCG 478
           ++ V+ +    VCG
Sbjct: 430 NVCVSSSRGGVVCG 443


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,531,577
Number of Sequences: 37866
Number of extensions: 880401
Number of successful extensions: 9427
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 508
Number of HSP's that attempted gapping in prelim test: 5407
Number of HSP's gapped (non-prelim): 2953
length of query: 535
length of database: 18,247,518
effective HSP length: 107
effective length of query: 428
effective length of database: 14,195,856
effective search space: 6075826368
effective search space used: 6075826368
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.