Search of human proteins with 32528268

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32528268 glutamate receptor, metabotropic 7 isoform b
precursor [Homo sapiens]
         (922 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32528268 glutamate receptor, metabotropic 7 isoform b precurs...  1877   0.0  
gi|4504147 glutamate receptor, metabotropic 7 isoform a precurso...  1828   0.0  
gi|187960069 glutamate receptor, metabotropic 8 isoform b precur...  1378   0.0  
gi|187960067 glutamate receptor, metabotropic 8 isoform a precur...  1377   0.0  
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]         1305   0.0  
gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo ...  1218   0.0  
gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo s...   732   0.0  
gi|66529100 glutamate receptor, metabotropic 2 isoform a precurs...   720   0.0  
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur...   644   0.0  
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso...   644   0.0  
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre...   642   0.0  
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr...   642   0.0  
gi|37577159 calcium-sensing receptor [Homo sapiens]                   400   e-111
gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]          241   2e-63
gi|112807234 G protein-coupled receptor, family C, group 6, memb...   230   4e-60
gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]           209   1e-53
gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo ...   207   5e-53
gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens]         202   9e-52
gi|29294619 sweet taste receptor T1r isoform c [Homo sapiens]         116   8e-26
gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens]         105   1e-22
gi|40255245 G protein-coupled receptor 51 [Homo sapiens]               65   3e-10
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform...    55   2e-07
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    55   2e-07
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    55   2e-07
gi|29294621 sweet taste receptor T1r isoform d [Homo sapiens]          49   2e-05
gi|7706451 G protein-coupled receptor, family C, group 5, member...    45   4e-04
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]     40   0.010
gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]     40   0.010
gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]     40   0.010
gi|93352554 GPR158-like 1 [Homo sapiens]                               40   0.010

>gi|32528268 glutamate receptor, metabotropic 7 isoform b precursor
           [Homo sapiens]
          Length = 922

 Score = 1877 bits (4861), Expect = 0.0
 Identities = 922/922 (100%), Positives = 922/922 (100%)

Query: 1   MVQLRKLLRVLTLMKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK 60
           MVQLRKLLRVLTLMKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK
Sbjct: 1   MVQLRKLLRVLTLMKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK 60

Query: 61  GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL 120
           GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL
Sbjct: 61  GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL 120

Query: 121 TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA 180
           TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA
Sbjct: 121 TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA 180

Query: 181 STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ 240
           STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ
Sbjct: 181 STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ 240

Query: 241 ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK 300
           ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK
Sbjct: 241 ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK 300

Query: 301 RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR 360
           RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR
Sbjct: 301 RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR 360

Query: 361 NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH 420
           NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH
Sbjct: 361 NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH 420

Query: 421 ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIF 480
           ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIF
Sbjct: 421 ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIF 480

Query: 481 QYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTP 540
           QYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTP
Sbjct: 481 QYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTP 540

Query: 541 CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAML 600
           CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAML
Sbjct: 541 CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAML 600

Query: 601 GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV 660
           GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV
Sbjct: 601 GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV 660

Query: 661 FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW 720
           FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW
Sbjct: 661 FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW 720

Query: 721 FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV 780
           FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV
Sbjct: 721 FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV 780

Query: 781 PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML 840
           PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML
Sbjct: 781 PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML 840

Query: 841 YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNN 900
           YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNN
Sbjct: 841 YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNN 900

Query: 901 CIPPVRKSVQKSVTWYTIPPTV 922
           CIPPVRKSVQKSVTWYTIPPTV
Sbjct: 901 CIPPVRKSVQKSVTWYTIPPTV 922


>gi|4504147 glutamate receptor, metabotropic 7 isoform a precursor
           [Homo sapiens]
          Length = 915

 Score = 1828 bits (4734), Expect = 0.0
 Identities = 899/900 (99%), Positives = 900/900 (100%)

Query: 1   MVQLRKLLRVLTLMKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK 60
           MVQLRKLLRVLTLMKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK
Sbjct: 1   MVQLRKLLRVLTLMKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK 60

Query: 61  GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL 120
           GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL
Sbjct: 61  GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL 120

Query: 121 TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA 180
           TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA
Sbjct: 121 TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA 180

Query: 181 STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ 240
           STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ
Sbjct: 181 STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ 240

Query: 241 ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK 300
           ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK
Sbjct: 241 ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK 300

Query: 301 RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR 360
           RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR
Sbjct: 301 RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR 360

Query: 361 NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH 420
           NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH
Sbjct: 361 NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH 420

Query: 421 ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIF 480
           ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIF
Sbjct: 421 ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIF 480

Query: 481 QYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTP 540
           QYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTP
Sbjct: 481 QYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTP 540

Query: 541 CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAML 600
           CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAML
Sbjct: 541 CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAML 600

Query: 601 GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV 660
           GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV
Sbjct: 601 GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV 660

Query: 661 FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW 720
           FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW
Sbjct: 661 FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW 720

Query: 721 FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV 780
           FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV
Sbjct: 721 FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV 780

Query: 781 PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML 840
           PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML
Sbjct: 781 PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML 840

Query: 841 YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNN 900
           YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPN+
Sbjct: 841 YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNS 900


>gi|187960069 glutamate receptor, metabotropic 8 isoform b precursor
           [Homo sapiens]
          Length = 908

 Score = 1378 bits (3566), Expect = 0.0
 Identities = 661/860 (76%), Positives = 759/860 (88%), Gaps = 4/860 (0%)

Query: 41  HSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVT 100
           HSIR++GD+ LGGLFPVHAKG  GVPCG++K+E GIHRLEAMLYA+DQIN DP+LL N+T
Sbjct: 38  HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNIT 97

Query: 101 LGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSS 160
           LG RILDTCSRDTYALEQSLTFVQALI+KD SDV+C NG+PP+F KP+K+ GVIGA+ SS
Sbjct: 98  LGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASS 157

Query: 161 VSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNY 220
           VSIMVANILRLF+IPQISYASTAPELSD+ RYDFFSRVVPPDS+QAQAMVDIV ALGWNY
Sbjct: 158 VSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNY 217

Query: 221 VSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNS 280
           VSTLASEG+YGE GVE+FTQIS+E GG+CIAQS +IP+E   R  +F++IIK+LL+TPN+
Sbjct: 218 VSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE--PRPGEFEKIIKRLLETPNA 275

Query: 281 RAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKR 340
           RAV++FAN++DI++IL AAK+ +Q GHFLW+GSDSWGSKI P++Q E+IAEGA+TI PKR
Sbjct: 276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKR 335

Query: 341 ATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDS 400
           A+++GFD YF SRTL NNRRNVWFAE+WEENF CKL   G K+    +KCTG ERI +DS
Sbjct: 336 ASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHG-KRNSHIKKCTGLERIARDS 394

Query: 401 NYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGS 460
           +YEQEGKVQFVIDAVY+MA+ALH+M+KDLC  Y G+CP M    GK+LL YIR VNFNGS
Sbjct: 395 SYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGS 454

Query: 461 AGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPA 520
           AGTPV FN+NGDAPGRYDIFQYQ TN S   Y++IG WT++L L +EDMQW       PA
Sbjct: 455 AGTPVTFNENGDAPGRYDIFQYQITNKSTE-YKVIGHWTNQLHLKVEDMQWAHREHTHPA 513

Query: 521 SVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIP 580
           SVC+LPCKPG+RKKT KG PCCW CE C+GY YQ DE++C+ CP DQRPN NRTGCQ IP
Sbjct: 514 SVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIP 573

Query: 581 IIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCY 640
           IIKLEWHSPWAV+PVF+A+LGIIAT FV+ TF+RYNDTPIVRASGRELSYVLLTGIFLCY
Sbjct: 574 IIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCY 633

Query: 641 IITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPT 700
            ITFLMIA PD  +CSFRRVFLGLGMC SYAALLTKTNRI+RIFEQGKKSVTAP+ ISP 
Sbjct: 634 SITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPA 693

Query: 701 SQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSL 760
           SQL IT SLISVQLLGVF+WF VDPP+IIIDY E +T++PE+ARGVLKCDI+DL +ICSL
Sbjct: 694 SQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSL 753

Query: 761 GYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYI 820
           GYSILLMVTCTVYAIKTRGVPE FNEAKPIGFTMYTTCI+WLAFIPIFFGTAQSAEK+YI
Sbjct: 754 GYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYI 813

Query: 821 QTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKP 880
           QTTTLT+SM+LSASV+LGMLYMPKVYIIIFHPE NVQKRKRSFKAVVTAATM S+L  K 
Sbjct: 814 QTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKG 873

Query: 881 SDRPNGEAKTELCENVDPNN 900
           +DRPNGE K+ELCE+++ N+
Sbjct: 874 NDRPNGEVKSELCESLETNS 893


>gi|187960067 glutamate receptor, metabotropic 8 isoform a precursor
           [Homo sapiens]
          Length = 908

 Score = 1377 bits (3565), Expect = 0.0
 Identities = 661/859 (76%), Positives = 758/859 (88%), Gaps = 4/859 (0%)

Query: 41  HSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVT 100
           HSIR++GD+ LGGLFPVHAKG  GVPCG++K+E GIHRLEAMLYA+DQIN DP+LL N+T
Sbjct: 38  HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNIT 97

Query: 101 LGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSS 160
           LG RILDTCSRDTYALEQSLTFVQALI+KD SDV+C NG+PP+F KP+K+ GVIGA+ SS
Sbjct: 98  LGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASS 157

Query: 161 VSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNY 220
           VSIMVANILRLF+IPQISYASTAPELSD+ RYDFFSRVVPPDS+QAQAMVDIV ALGWNY
Sbjct: 158 VSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNY 217

Query: 221 VSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNS 280
           VSTLASEG+YGE GVE+FTQIS+E GG+CIAQS +IP+E   R  +F++IIK+LL+TPN+
Sbjct: 218 VSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE--PRPGEFEKIIKRLLETPNA 275

Query: 281 RAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKR 340
           RAV++FAN++DI++IL AAK+ +Q GHFLW+GSDSWGSKI P++Q E+IAEGA+TI PKR
Sbjct: 276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKR 335

Query: 341 ATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDS 400
           A+++GFD YF SRTL NNRRNVWFAE+WEENF CKL   G K+    +KCTG ERI +DS
Sbjct: 336 ASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHG-KRNSHIKKCTGLERIARDS 394

Query: 401 NYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGS 460
           +YEQEGKVQFVIDAVY+MA+ALH+M+KDLC  Y G+CP M    GK+LL YIR VNFNGS
Sbjct: 395 SYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGS 454

Query: 461 AGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPA 520
           AGTPV FN+NGDAPGRYDIFQYQ TN S   Y++IG WT++L L +EDMQW       PA
Sbjct: 455 AGTPVTFNENGDAPGRYDIFQYQITNKSTE-YKVIGHWTNQLHLKVEDMQWAHREHTHPA 513

Query: 521 SVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIP 580
           SVC+LPCKPG+RKKT KG PCCW CE C+GY YQ DE++C+ CP DQRPN NRTGCQ IP
Sbjct: 514 SVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIP 573

Query: 581 IIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCY 640
           IIKLEWHSPWAV+PVF+A+LGIIAT FV+ TF+RYNDTPIVRASGRELSYVLLTGIFLCY
Sbjct: 574 IIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCY 633

Query: 641 IITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPT 700
            ITFLMIA PD  +CSFRRVFLGLGMC SYAALLTKTNRI+RIFEQGKKSVTAP+ ISP 
Sbjct: 634 SITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPA 693

Query: 701 SQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSL 760
           SQL IT SLISVQLLGVF+WF VDPP+IIIDY E +T++PE+ARGVLKCDI+DL +ICSL
Sbjct: 694 SQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSL 753

Query: 761 GYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYI 820
           GYSILLMVTCTVYAIKTRGVPE FNEAKPIGFTMYTTCI+WLAFIPIFFGTAQSAEK+YI
Sbjct: 754 GYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYI 813

Query: 821 QTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKP 880
           QTTTLT+SM+LSASV+LGMLYMPKVYIIIFHPE NVQKRKRSFKAVVTAATM S+L  K 
Sbjct: 814 QTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKG 873

Query: 881 SDRPNGEAKTELCENVDPN 899
           +DRPNGE K+ELCE+++ N
Sbjct: 874 NDRPNGEVKSELCESLETN 892


>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
          Length = 912

 Score = 1305 bits (3376), Expect = 0.0
 Identities = 626/885 (70%), Positives = 751/885 (84%), Gaps = 5/885 (0%)

Query: 15  KFPCCVLEVLLCALAAAARGQEMYAPH--SIRIEGDVTLGGLFPVHAKGPSGVPCGDIKR 72
           + P C+L  L      ++ G+    PH  SIRI+GD+TLGGLFPVH +G  G PCG++K+
Sbjct: 13  RLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKPCGELKK 72

Query: 73  ENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTS 132
           E GIHRLEAML+ALD+IN+DP+LLPN+TLGARILDTCSRDT+ALEQSLTFVQALI+KD +
Sbjct: 73  EKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGT 132

Query: 133 DVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRY 192
           +VRC +G PP+  KPE+VVGVIGASGSSVSIMVANILRLF+IPQISYASTAP+LSD+ RY
Sbjct: 133 EVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRY 192

Query: 193 DFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQ 252
           DFFSRVVP D++QAQAMVDIV+AL WNYVST+ASEGSYGE GVE+F Q S+E GG+CIAQ
Sbjct: 193 DFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQ 252

Query: 253 SVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVG 312
           SV+IP+E K    +FD+II++LL+T N+RAV+IFAN++DI+++L AA+RA+Q GHF W+G
Sbjct: 253 SVKIPREPKAG--EFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMG 310

Query: 313 SDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENF 372
           SDSWGSKI P+   E++AEGA+TI PKR +V GFD YF+SRTL+NNRRN+WFAE+WE+NF
Sbjct: 311 SDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNF 370

Query: 373 NCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCAD 432
           +CKL+    KK    +KCT +ERIG+DS YEQEGKVQFVIDAVYAM HALH M++DLC  
Sbjct: 371 HCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPG 430

Query: 433 YRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGY 492
             G+CP M+   G +LLKYIRNVNF+G AG PV FN+NGDAPGRYDI+QYQ  N S   Y
Sbjct: 431 RVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAE-Y 489

Query: 493 RLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQ 552
           ++IG WTD L L IE M W    +++P S+C+LPC+PG+RKKT KG PCCW CEPC GYQ
Sbjct: 490 KVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQ 549

Query: 553 YQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATF 612
           YQ D  TC+ CPYD RP ENRTGC+ IPIIKLEW SPWAV+P+FLA++GI AT+FV+ TF
Sbjct: 550 YQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITF 609

Query: 613 IRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAA 672
           +RYNDTPIV+ASGRELSYVLL GIFLCY  TFLMIA+PD+  CS RR+FLGLGM ISYAA
Sbjct: 610 VRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAA 669

Query: 673 LLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDY 732
           LLTKTNRIYRIFEQGK+SV+APR ISP SQLAIT SLIS+QLLG+ +WF VDP + ++D+
Sbjct: 670 LLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDF 729

Query: 733 DEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGF 792
            + +T++P  ARGVLKCDI+DL +IC LGYS+LLMVTCTVYAIKTRGVPE FNEAKPIGF
Sbjct: 730 QDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGF 789

Query: 793 TMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHP 852
           TMYTTCIVWLAFIPIFFGT+QSA+KLYIQTTTLT+S++LSASV+LGMLYMPKVYII+FHP
Sbjct: 790 TMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHP 849

Query: 853 ELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVD 897
           E NV KRKRS KAVVTAATMS++ + K + RPNGEAK+ELCEN++
Sbjct: 850 EQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLE 894


>gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo
           sapiens]
          Length = 877

 Score = 1218 bits (3152), Expect = 0.0
 Identities = 581/857 (67%), Positives = 710/857 (82%), Gaps = 9/857 (1%)

Query: 21  LEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLE 80
           L V L  LA  A+     A  S+R+ G +TLGGLFPVHA+G +G  CG +K+E G+HRLE
Sbjct: 11  LLVALLPLAWLAQAGLARAAGSVRLAGGLTLGGLFPVHARGAAGRACGQLKKEQGVHRLE 70

Query: 81  AMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQK----DTSDVRC 136
           AMLYALD++N+DP LLP V LGAR+LDTCSRDTYALEQ+L+FVQALI+     D   VRC
Sbjct: 71  AMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEVGVRC 130

Query: 137 TNGEPPVF-VKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFF 195
             G PP+    PE+VV V+GAS SSVSIMVAN+LRLF IPQISYASTAPELSD  RYDFF
Sbjct: 131 PGGVPPLRPAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFF 190

Query: 196 SRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVR 255
           SRVVPPDS+QAQAMVDIV+ALGWNYVSTLASEG+YGE GVE+F QIS+EAGG+CIAQS++
Sbjct: 191 SRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIK 250

Query: 256 IPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDS 315
           IP+E K    +F ++I++L++TPN+R ++IFAN++DI+++L AA++A+  GHFLWVGSDS
Sbjct: 251 IPREPKPG--EFSKVIRRLMETPNARGIIIFANEDDIRRVLEAARQANLTGHFLWVGSDS 308

Query: 316 WGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCK 375
           WG+K +P+   ED+A GAITI PKRA+++GFD YF +R+LENNRRN+WFAE+WEENFNCK
Sbjct: 309 WGAKTSPILSLEDVAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCK 368

Query: 376 LTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRG 435
           LT SG++ +D+ RKCTG+ERIG+DS YEQEGKVQFVIDAVYA+AHALH M++ LC  + G
Sbjct: 369 LTSSGTQSDDSTRKCTGEERIGRDSTYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTG 428

Query: 436 VCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTN--TSNPGYR 493
           +CP ME   G+ LL+YIR V FNGSAGTPVMFN+NGDAPGRYDIFQYQ TN   S+ GY+
Sbjct: 429 LCPAMEPTDGRMLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQ 488

Query: 494 LIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQY 553
            +GQW + L+L++E +QW     E+P+S+C+LPC PG+RKK  KG PCCW CE CDGY++
Sbjct: 489 AVGQWAETLRLDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHCEACDGYRF 548

Query: 554 QFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFI 613
           Q DE TC+ CP D RP  N TGC+  P+++L W SPWA  P+ LA+LGI+AT  V+ATF+
Sbjct: 549 QVDEFTCEACPGDMRPTPNHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVATTTVVATFV 608

Query: 614 RYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAAL 673
           RYN+TPIVRASGRELSYVLLTGIFL Y ITFLM+A+P  AVC+ RR+FLGLG  +SY+AL
Sbjct: 609 RYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLGTTLSYSAL 668

Query: 674 LTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYD 733
           LTKTNRIYRIFEQGK+SVT P  ISPTSQL IT SL S+Q++G+  W G  PP+ +IDY+
Sbjct: 669 LTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLTSLQVVGMIAWLGARPPHSVIDYE 728

Query: 734 EHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFT 793
           E +T++PEQARGVLKCD++DL +I  LGYS+LLMVTCTVYAIK RGVPE FNEAKPIGFT
Sbjct: 729 EQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIGFT 788

Query: 794 MYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPE 853
           MYTTCI+WLAF+PIFFGTAQSAEK+YIQTTTLT+S++LSASV+LGMLY+PK Y+I+FHPE
Sbjct: 789 MYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFHPE 848

Query: 854 LNVQKRKRSFKAVVTAA 870
            NVQKRKRS KA  T A
Sbjct: 849 QNVQKRKRSLKATSTVA 865


>gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo
           sapiens]
          Length = 879

 Score =  732 bits (1889), Expect = 0.0
 Identities = 387/849 (45%), Positives = 528/849 (62%), Gaps = 34/849 (4%)

Query: 21  LEVLLCALAAA----ARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGI 76
           L+VL  AL +     + G   +    I+IEGD+ LGGLFP++ KG     CG I  + GI
Sbjct: 7   LQVLTLALFSKGFLLSLGDHNFLRREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGI 66

Query: 77  HRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQK-DTSDVR 135
            RLEAML+A+D+IN D  LLP V LG  ILDTCSRDTYALEQSL FV+A + K D ++  
Sbjct: 67  QRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEAEYM 126

Query: 136 CTNGEPPVFVK-PEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDF 194
           C +G   +    P  + GVIG S SSVSI VAN+LRLFQIPQISYAST+ +LSD  RYD+
Sbjct: 127 CPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDY 186

Query: 195 FSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSV 254
           F+R VPPD +QA+AM +I++   W YVST+ASEG YGE G+E+F Q ++    +CIA + 
Sbjct: 187 FARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEAR-LRNICIATAE 245

Query: 255 RIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSD 314
           ++ +    ++  +D +I++LL  PN+R VV+F   +D ++++AAA RA+    F WV SD
Sbjct: 246 KVGRSNIRKS--YDSVIRELLQKPNARVVVLFMRSDDSRELIAAASRAN--ASFTWVASD 301

Query: 315 SWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNC 374
            WG++ + +   E +A GAIT++     V  FD YF S    NN RN WF ++WE+ F C
Sbjct: 302 GWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQC 361

Query: 375 KLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYR 434
            L      K +  R C     I   SNYEQE K+ FV++AVYAMAHALH M + LC +  
Sbjct: 362 SL----QNKRNHRRVCDKHLAIDS-SNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTT 416

Query: 435 GVCPEMEQAGGKKLLK-YIRNVNF------NGSAGTPVMFNKNGDAPGRYDIFQYQTTNT 487
            +C  M+   GKKL K Y+  +NF      N  A + V F+  GD  GRY++F +Q    
Sbjct: 417 KLCDAMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQNVG- 475

Query: 488 SNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTPCCWTCEP 547
               Y  +G W + L L++  + W +    +P S C+ PC P + K  Q G  CCW C P
Sbjct: 476 GKYSYLKVGHWAETLSLDVNSIHWSRN--SVPTSQCSDPCAPNEMKNMQPGDVCCWICIP 533

Query: 548 CDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIF 607
           C+ Y+Y  DE TC  C   Q P  + TGC D+P   + W   WA+ PV +A LG + T  
Sbjct: 534 CEPYEYLADEFTCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCM 593

Query: 608 VMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMC 667
           V+  FI++N+TP+V+ASGREL Y+LL G+ L Y +TF  IAKP   +C+ RR+ LG    
Sbjct: 594 VVTVFIKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFA 653

Query: 668 ISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPN 727
           I Y+ALLTKTN I RIF+  K     P+ ISP+SQ+ I   LI VQ++ V +W  ++ P 
Sbjct: 654 ICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPG 713

Query: 728 IIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEA 787
                    T+  ++   +LKC++ D  ++ SL Y ++L++ CTVYA KTR  PENFNEA
Sbjct: 714 -----TRRYTLAEKRETVILKCNVKDSSMLISLTYDVILVILCTVYAFKTRKCPENFNEA 768

Query: 788 KPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYI 847
           K IGFTMYTTCI+WLAF+PIF+ T+       +QTTT+ IS++LS  V LG L+ PKV+I
Sbjct: 769 KFIGFTMYTTCIIWLAFLPIFYVTSSDYR---VQTTTMCISVSLSGFVVLGCLFAPKVHI 825

Query: 848 IIFHPELNV 856
           I+F P+ NV
Sbjct: 826 ILFQPQKNV 834


>gi|66529100 glutamate receptor, metabotropic 2 isoform a precursor
           [Homo sapiens]
          Length = 872

 Score =  720 bits (1858), Expect = 0.0
 Identities = 388/865 (44%), Positives = 524/865 (60%), Gaps = 39/865 (4%)

Query: 21  LEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLE 80
           L  LL    A A G    A   + +EGD+ LGGLFPVH KG     CG +    GI RLE
Sbjct: 7   LLALLLLWGAVAEGP---AKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLE 63

Query: 81  AMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVR--CTN 138
           AML+ALD+IN DP+LLP V LGA ILD+CS+DT+ALEQ+L FV+A + +     R  C +
Sbjct: 64  AMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPD 123

Query: 139 GEPPVFVK-PEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSR 197
           G        P  + GVIG S S VSI VAN+LRLFQIPQISYAST+ +LSD  RYD+F+R
Sbjct: 124 GSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFAR 183

Query: 198 VVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIP 257
            VPPD FQA+AM +I++   W YVST+ASEG YGE G+E+F ++   A  +C+A S ++ 
Sbjct: 184 TVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAF-ELEARARNICVATSEKVG 242

Query: 258 QERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWG 317
           +        F+ +++ LL  P++R  V+F   ED +++LAA++R +    F WV SD WG
Sbjct: 243 RAMSRAA--FEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLN--ASFTWVASDGWG 298

Query: 318 SKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLT 377
           +  + +   E  AEGAITI+     +  F +YF S    NN RN WF E+WE+ F C   
Sbjct: 299 ALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFR 358

Query: 378 ISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVC 437
                     R C       +   +EQE K+ FV++AVYAMAHALH+M++ LC +   +C
Sbjct: 359 ---------QRDCAAHSL--RAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLC 407

Query: 438 PEMEQAGGKKLLK-YIRNVNFNG-----SAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPG 491
             M    G++L K ++ NV F+           V F++ GD  GRY+IF Y    +    
Sbjct: 408 DAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYR 467

Query: 492 YRLIGQWTDELQLNIEDMQWGK-GVREIPASVCTLPCKPGQRKKTQKGTPCCWTCEPCDG 550
           Y+ +G W + L L+   + W       +PAS C+ PC   + K  Q G  CCW C PC  
Sbjct: 468 YQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQP 527

Query: 551 YQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMA 610
           Y+Y+ DE TC  C     PN + TGC ++P   + W   WAV PV +A LG +AT+FV+ 
Sbjct: 528 YEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLG 587

Query: 611 TFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISY 670
            F+R+N TP+V+ASGREL Y+LL G+FLCY +TF+ IAKP  AVC+ RR+ LG    + Y
Sbjct: 588 VFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCY 647

Query: 671 AALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIII 730
           +ALLTKTNRI RIF   ++    PR ISP SQ+AI  +LIS QLL V  W  V+ P    
Sbjct: 648 SALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPG--- 704

Query: 731 DYDEHKTMNPEQARGV-LKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKP 789
                K   PE+   V L+C+  D  ++ SL Y++LL+  CT+YA KTR  PENFNEAK 
Sbjct: 705 ---TGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKF 761

Query: 790 IGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIII 849
           IGFTMYTTCI+WLAF+PIF+ T+       +QTTT+ +S++LS SV LG L+ PK++II+
Sbjct: 762 IGFTMYTTCIIWLAFLPIFYVTSSDYR---VQTTTMCVSVSLSGSVVLGCLFAPKLHIIL 818

Query: 850 FHPELNVQKRKRSFKAVVTAATMSS 874
           F P+ NV   +       +AA  +S
Sbjct: 819 FQPQKNVVSHRAPTSRFGSAAARAS 843


>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
           [Homo sapiens]
          Length = 1212

 Score =  644 bits (1661), Expect = 0.0
 Identities = 351/850 (41%), Positives = 509/850 (59%), Gaps = 33/850 (3%)

Query: 20  VLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGV----PCGDIKRENG 75
           +L VLL         Q         + GD+ +G LF VH +          CG ++ + G
Sbjct: 6   ILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYG 65

Query: 76  IHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQ-ALIQKDTSD- 133
           I R+EAML+ L++INSDP LLPN+TLG  I D+C     ALEQS+ F++ +LI  +  + 
Sbjct: 66  IQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEG 125

Query: 134 -VRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRY 192
            VRC +G    F   + +VGVIG   SSV+I V N+L+LF IPQI+Y++T+ +LSD   +
Sbjct: 126 LVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLF 185

Query: 193 DFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQ 252
            +F RVVP D+ QA+AMVDIVK   W YVS + +EG+YGE G+E+F  +S + G +CIA 
Sbjct: 186 KYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEG-ICIAH 244

Query: 253 SVRIPQERKDRTIDFDRIIKQLLD-TPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWV 311
           S +I     +++  FD+++K+L    P +R V  F     ++ +L A +R    G FL +
Sbjct: 245 SYKIYSNAGEQS--FDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLL 302

Query: 312 GSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEEN 371
           GSD W  + +    ++  A G ITI+ +   V+ FD Y+     E N RN WF E+W+  
Sbjct: 303 GSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHR 362

Query: 372 FNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCA 431
           F C+L   G  +E++    T    +   +++ Q+ K+ FVI+A+Y+MA+ LH+M   LC 
Sbjct: 363 FQCRL--EGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP 420

Query: 432 DYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPG 491
            Y G+C  M+   G+KLL+ +   NF G +G  ++F++NGD+PGRY+I  ++        
Sbjct: 421 GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD 480

Query: 492 YRLIGQWTD-ELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKG-TPCCWTCEPCD 549
           Y  +G W + EL+++ +D  W K    I  SVC+ PC+ GQ K  +KG   CCWTC PC 
Sbjct: 481 YINVGSWDNGELKMD-DDEVWSKK-SNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCK 538

Query: 550 GYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVM 609
             +Y FDE TC+ C     P ++ TGC  IP+  L W  P  +  V  A LG++AT+FV 
Sbjct: 539 ENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVT 598

Query: 610 ATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCIS 669
             FI Y DTP+V++S REL Y++L GI L Y+ TF +IAKP    C  +R+ +GL   +S
Sbjct: 599 VVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMS 658

Query: 670 YAALLTKTNRIYRIFEQGKKSVTA--PRLISPTSQLAITSSLISVQLLGVFIWFGVDPPN 727
           Y+AL+TKTNRI RI    KK +    PR +S  +QL I   LI +QL  +   F ++PP+
Sbjct: 659 YSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPD 718

Query: 728 IIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEA 787
           I+ DY       P      L C+ T+L ++  LGY+ LL+++CT YA KTR VP NFNEA
Sbjct: 719 IMHDY-------PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEA 771

Query: 788 KPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYI 847
           K I FTMYTTCI+WLAF+PI+FG+         +  T+  S++LSA+VALG +++PKVYI
Sbjct: 772 KYIAFTMYTTCIIWLAFVPIYFGS-------NYKIITMCFSVSLSATVALGCMFVPKVYI 824

Query: 848 IIFHPELNVQ 857
           I+  PE NV+
Sbjct: 825 ILAKPERNVR 834


>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
           [Homo sapiens]
          Length = 1180

 Score =  644 bits (1661), Expect = 0.0
 Identities = 351/850 (41%), Positives = 509/850 (59%), Gaps = 33/850 (3%)

Query: 20  VLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGV----PCGDIKRENG 75
           +L VLL         Q         + GD+ +G LF VH +          CG ++ + G
Sbjct: 6   ILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYG 65

Query: 76  IHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQ-ALIQKDTSD- 133
           I R+EAML+ L++INSDP LLPN+TLG  I D+C     ALEQS+ F++ +LI  +  + 
Sbjct: 66  IQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEG 125

Query: 134 -VRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRY 192
            VRC +G    F   + +VGVIG   SSV+I V N+L+LF IPQI+Y++T+ +LSD   +
Sbjct: 126 LVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLF 185

Query: 193 DFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQ 252
            +F RVVP D+ QA+AMVDIVK   W YVS + +EG+YGE G+E+F  +S + G +CIA 
Sbjct: 186 KYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEG-ICIAH 244

Query: 253 SVRIPQERKDRTIDFDRIIKQLLD-TPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWV 311
           S +I     +++  FD+++K+L    P +R V  F     ++ +L A +R    G FL +
Sbjct: 245 SYKIYSNAGEQS--FDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLL 302

Query: 312 GSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEEN 371
           GSD W  + +    ++  A G ITI+ +   V+ FD Y+     E N RN WF E+W+  
Sbjct: 303 GSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHR 362

Query: 372 FNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCA 431
           F C+L   G  +E++    T    +   +++ Q+ K+ FVI+A+Y+MA+ LH+M   LC 
Sbjct: 363 FQCRL--EGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP 420

Query: 432 DYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPG 491
            Y G+C  M+   G+KLL+ +   NF G +G  ++F++NGD+PGRY+I  ++        
Sbjct: 421 GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD 480

Query: 492 YRLIGQWTD-ELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKG-TPCCWTCEPCD 549
           Y  +G W + EL+++ +D  W K    I  SVC+ PC+ GQ K  +KG   CCWTC PC 
Sbjct: 481 YINVGSWDNGELKMD-DDEVWSKK-SNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCK 538

Query: 550 GYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVM 609
             +Y FDE TC+ C     P ++ TGC  IP+  L W  P  +  V  A LG++AT+FV 
Sbjct: 539 ENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVT 598

Query: 610 ATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCIS 669
             FI Y DTP+V++S REL Y++L GI L Y+ TF +IAKP    C  +R+ +GL   +S
Sbjct: 599 VVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMS 658

Query: 670 YAALLTKTNRIYRIFEQGKKSVTA--PRLISPTSQLAITSSLISVQLLGVFIWFGVDPPN 727
           Y+AL+TKTNRI RI    KK +    PR +S  +QL I   LI +QL  +   F ++PP+
Sbjct: 659 YSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPD 718

Query: 728 IIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEA 787
           I+ DY       P      L C+ T+L ++  LGY+ LL+++CT YA KTR VP NFNEA
Sbjct: 719 IMHDY-------PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEA 771

Query: 788 KPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYI 847
           K I FTMYTTCI+WLAF+PI+FG+         +  T+  S++LSA+VALG +++PKVYI
Sbjct: 772 KYIAFTMYTTCIIWLAFVPIYFGS-------NYKIITMCFSVSLSATVALGCMFVPKVYI 824

Query: 848 IIFHPELNVQ 857
           I+  PE NV+
Sbjct: 825 ILAKPERNVR 834


>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
           precursor [Homo sapiens]
          Length = 906

 Score =  642 bits (1657), Expect = 0.0
 Identities = 365/869 (42%), Positives = 519/869 (59%), Gaps = 47/869 (5%)

Query: 11  LTLMKFPCCVLEVLLC-------ALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPS 63
           L L  FP   LEV L         L A A  Q   A    R++GDV +G LF VH + P+
Sbjct: 4   LLLFFFPAIFLEVSLLPRSPGRKVLLAGASSQRSVA----RMDGDVIIGALFSVHHQPPA 59

Query: 64  G-VP---CGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQS 119
             VP   CG+I+ + GI R+EAM + LD+IN+DP LLPN+TLG+ I D+C   + ALEQS
Sbjct: 60  EKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQS 119

Query: 120 LTFVQALI-----QKDTSDVRCTNGE--PPVFVKPEKVVGVIGASGSSVSIMVANILRLF 172
           + F++  +     +KD  +    +G+  PP   K + + GVIG   SSV+I V N+L+LF
Sbjct: 120 IEFIRDSLISIRDEKDGINRCLPDGQSLPPGRTK-KPIAGVIGPGSSSVAIQVQNLLQLF 178

Query: 173 QIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGE 232
            IPQI+Y++T+ +LSD   Y +F RVVP D+ QA+AM+DIVK   W YVS + +EG+YGE
Sbjct: 179 DIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGE 238

Query: 233 KGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDT-PNSRAVVIFANDED 291
            G+++F +++ + G LCIA S +I     +++  FDR++++L +  P +R VV F     
Sbjct: 239 SGMDAFKELAAQEG-LCIAHSDKIYSNAGEKS--FDRLLRKLRERLPKARVVVCFCEGMT 295

Query: 292 IKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFT 351
           ++ +L+A +R   VG F  +GSD W  +   +  +E  A G ITI+ +   V  FD YF 
Sbjct: 296 VRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFL 355

Query: 352 SRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFV 411
              L+ N RN WF E+W+  F C+L     +  +  R CTG E +  + NY Q+ K+ FV
Sbjct: 356 KLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKRICTGNESL--EENYVQDSKMGFV 413

Query: 412 IDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNG 471
           I+A+YAMAH L +M+  LC  + G+C  M+   G KLL ++   +F G +G  V F++ G
Sbjct: 414 INAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGSKLLDFLIKSSFIGVSGEEVWFDEKG 473

Query: 472 DAPGRYDIFQYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQ 531
           DAPGRYDI   Q T  +   Y  +G W + + LNI+D +       +  SVC+ PC  GQ
Sbjct: 474 DAPGRYDIMNLQYTEANRYDYVHVGTWHEGV-LNIDDYKIQMNKSGVVRSVCSEPCLKGQ 532

Query: 532 RKKTQKG-TPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPW 590
            K  +KG   CCW C  C   +Y  DE TC+ C     PN + TGC+ IP+  LEW +  
Sbjct: 533 IKVIRKGEVSCCWICTACKENEYVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIE 592

Query: 591 AVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKP 650
           ++I +  + LGI+ T+FV   F+ Y DTP+V++S REL Y++L GIFL Y+  F +IAKP
Sbjct: 593 SIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKP 652

Query: 651 DVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTA--PRLISPTSQLAITSS 708
               C  +R+ +GL   + Y+AL+TKTNRI RI    KK +    PR +S  +Q+ I S 
Sbjct: 653 TTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASI 712

Query: 709 LISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMV 768
           LISVQL  V     ++PP  I+ Y   K +        L C+ ++L ++  LGY+ LL++
Sbjct: 713 LISVQLTLVVTLIIMEPPMPILSYPSIKEV-------YLICNTSNLGVVAPLGYNGLLIM 765

Query: 769 TCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTIS 828
           +CT YA KTR VP NFNEAK I FTMYTTCI+WLAF+PI+FG+        I TT   +S
Sbjct: 766 SCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGS-----NYKIITTCFAVS 820

Query: 829 MNLSASVALGMLYMPKVYIIIFHPELNVQ 857
             LS +VALG ++ PK+YIII  PE NV+
Sbjct: 821 --LSVTVALGCMFTPKMYIIIAKPERNVR 847


>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
           precursor [Homo sapiens]
          Length = 1194

 Score =  642 bits (1657), Expect = 0.0
 Identities = 365/869 (42%), Positives = 519/869 (59%), Gaps = 47/869 (5%)

Query: 11  LTLMKFPCCVLEVLLC-------ALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPS 63
           L L  FP   LEV L         L A A  Q   A    R++GDV +G LF VH + P+
Sbjct: 4   LLLFFFPAIFLEVSLLPRSPGRKVLLAGASSQRSVA----RMDGDVIIGALFSVHHQPPA 59

Query: 64  G-VP---CGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQS 119
             VP   CG+I+ + GI R+EAM + LD+IN+DP LLPN+TLG+ I D+C   + ALEQS
Sbjct: 60  EKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQS 119

Query: 120 LTFVQALI-----QKDTSDVRCTNGE--PPVFVKPEKVVGVIGASGSSVSIMVANILRLF 172
           + F++  +     +KD  +    +G+  PP   K + + GVIG   SSV+I V N+L+LF
Sbjct: 120 IEFIRDSLISIRDEKDGINRCLPDGQSLPPGRTK-KPIAGVIGPGSSSVAIQVQNLLQLF 178

Query: 173 QIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGE 232
            IPQI+Y++T+ +LSD   Y +F RVVP D+ QA+AM+DIVK   W YVS + +EG+YGE
Sbjct: 179 DIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGE 238

Query: 233 KGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDT-PNSRAVVIFANDED 291
            G+++F +++ + G LCIA S +I     +++  FDR++++L +  P +R VV F     
Sbjct: 239 SGMDAFKELAAQEG-LCIAHSDKIYSNAGEKS--FDRLLRKLRERLPKARVVVCFCEGMT 295

Query: 292 IKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFT 351
           ++ +L+A +R   VG F  +GSD W  +   +  +E  A G ITI+ +   V  FD YF 
Sbjct: 296 VRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFL 355

Query: 352 SRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFV 411
              L+ N RN WF E+W+  F C+L     +  +  R CTG E +  + NY Q+ K+ FV
Sbjct: 356 KLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKRICTGNESL--EENYVQDSKMGFV 413

Query: 412 IDAVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNG 471
           I+A+YAMAH L +M+  LC  + G+C  M+   G KLL ++   +F G +G  V F++ G
Sbjct: 414 INAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGSKLLDFLIKSSFIGVSGEEVWFDEKG 473

Query: 472 DAPGRYDIFQYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQ 531
           DAPGRYDI   Q T  +   Y  +G W + + LNI+D +       +  SVC+ PC  GQ
Sbjct: 474 DAPGRYDIMNLQYTEANRYDYVHVGTWHEGV-LNIDDYKIQMNKSGVVRSVCSEPCLKGQ 532

Query: 532 RKKTQKG-TPCCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPW 590
            K  +KG   CCW C  C   +Y  DE TC+ C     PN + TGC+ IP+  LEW +  
Sbjct: 533 IKVIRKGEVSCCWICTACKENEYVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIE 592

Query: 591 AVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKP 650
           ++I +  + LGI+ T+FV   F+ Y DTP+V++S REL Y++L GIFL Y+  F +IAKP
Sbjct: 593 SIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKP 652

Query: 651 DVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTA--PRLISPTSQLAITSS 708
               C  +R+ +GL   + Y+AL+TKTNRI RI    KK +    PR +S  +Q+ I S 
Sbjct: 653 TTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASI 712

Query: 709 LISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMV 768
           LISVQL  V     ++PP  I+ Y   K +        L C+ ++L ++  LGY+ LL++
Sbjct: 713 LISVQLTLVVTLIIMEPPMPILSYPSIKEV-------YLICNTSNLGVVAPLGYNGLLIM 765

Query: 769 TCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTIS 828
           +CT YA KTR VP NFNEAK I FTMYTTCI+WLAF+PI+FG+        I TT   +S
Sbjct: 766 SCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGS-----NYKIITTCFAVS 820

Query: 829 MNLSASVALGMLYMPKVYIIIFHPELNVQ 857
             LS +VALG ++ PK+YIII  PE NV+
Sbjct: 821 --LSVTVALGCMFTPKMYIIIAKPERNVR 847


>gi|37577159 calcium-sensing receptor [Homo sapiens]
          Length = 1078

 Score =  400 bits (1029), Expect = e-111
 Identities = 288/934 (30%), Positives = 437/934 (46%), Gaps = 91/934 (9%)

Query: 14  MKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVH----------AKGPS 63
           M F  C   +L      +A G +  A      +GD+ LGGLFP+H             P 
Sbjct: 1   MAFYSCCWVLLALTWHTSAYGPDQRAQK----KGDIILGGLFPIHFGVAAKDQDLKSRPE 56

Query: 64  GVPCGDIKREN--GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLT 121
            V C    R N  G   L+AM++A+++INS P LLPN+TLG RI DTC+  + ALE +L+
Sbjct: 57  SVEC---IRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLS 113

Query: 122 FV-QALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA 180
           FV Q  I     D  C   E          + V+GA+GS VS  VAN+L LF IPQ+SYA
Sbjct: 114 FVAQNKIDSLNLDEFCNCSE-----HIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYA 168

Query: 181 STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ 240
           S++  LS+  ++  F R +P D  QA AM DI++   WN+V T+A++  YG  G+E F +
Sbjct: 169 SSSRLLSNKNQFKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFRE 228

Query: 241 ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK 300
            ++E   +CI  S  I Q   +  I     + +++    ++ +V+F++  D++ ++    
Sbjct: 229 EAEERD-ICIDFSELISQYSDEEEIQH---VVEVIQNSTAKVIVVFSSGPDLEPLIKEIV 284

Query: 301 RADQVGHFLWVGSDSWGSK-INPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNR 359
           R +  G  +W+ S++W S  +  + Q+  +  G I    K   + GF  +        + 
Sbjct: 285 RRNITGK-IWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSV 343

Query: 360 RNVWFAEYWEENFNCKL-----------TISGSKKEDTDR----------KCTGQERIGK 398
            N +  E+WEE FNC L           T     +E  DR           CTG E I  
Sbjct: 344 HNGFAKEFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNSSTAFRPLCTGDENISS 403

Query: 399 -DSNYEQEGKVQF---VIDAVYAMAHALHHMNKDLCADYRGV-----CPEMEQAGGKKLL 449
            ++ Y     ++    V  AVY++AHAL  +    C   RG+     C ++++    ++L
Sbjct: 404 VETPYIDYTHLRISYNVYLAVYSIAHALQDIYT--CLPGRGLFTNGSCADIKKVEAWQVL 461

Query: 450 KYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNP-------GYRLIGQWTDEL 502
           K++R++NF  + G  V F++ GD  G Y I  +  +             Y +  +  + L
Sbjct: 462 KHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERL 521

Query: 503 QLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKGTP-CCWTCEPC-DG-YQYQFDEMT 559
            +N E + W    RE+P S C+  C  G RK   +G P CC+ C  C DG Y  + D   
Sbjct: 522 FINEEKILWSGFSREVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASA 581

Query: 560 CQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTP 619
           C  CP D   NEN T C    I  L W  P+ +     A+LGI  T FV+  FI++ +TP
Sbjct: 582 CNKCPDDFWSNENHTSCIAKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTP 641

Query: 620 IVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNR 679
           IV+A+ RELSY+LL  +  C+  +   I +P    C  R+   G+   +  + +L KTNR
Sbjct: 642 IVKATNRELSYLLLFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNR 701

Query: 680 IYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMN 739
           +  +FE    +    +      Q  +      +Q++   IW    PP+       ++   
Sbjct: 702 VLLVFEAKIPTSFHRKWWGLNLQFLLVFLCTFMQIVICVIWLYTAPPS------SYRNQE 755

Query: 740 PEQARGVLKCDITDLQIICSL-GYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTC 798
            E     + C    L  +  L GY+ LL   C  +A K+R +PENFNEAK I F+M    
Sbjct: 756 LEDEIIFITCHEGSLMALGFLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFF 815

Query: 799 IVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQK 858
           IVW++FIP +  T             L  S  L     L  ++  K+YII+F P  N  +
Sbjct: 816 IVWISFIPAYASTYGKFVSAVEVIAILAASFGL-----LACIFFNKIYIILFKPSRNTIE 870

Query: 859 RKR------SFKAVVTAATMSSRLSHKPSDRPNG 886
             R      +FK    A    S +S K S    G
Sbjct: 871 EVRCSTAAHAFKVAARATLRRSNVSRKRSSSLGG 904


>gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]
          Length = 839

 Score =  241 bits (615), Expect = 2e-63
 Identities = 233/874 (26%), Positives = 384/874 (43%), Gaps = 107/874 (12%)

Query: 24  LLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIK---------REN 74
           LL  LA  A   + Y P      GD  LGGLF +HA     V    ++         +  
Sbjct: 14  LLWVLAEPAENSDFYLP------GDYLLGGLFSLHANMKGIVHLNFLQVPMCKEYEVKVI 67

Query: 75  GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTC--SRDTYALEQSLTFVQAL--IQKD 130
           G + ++AM +A+++IN+D +LLP V LG  I+D C  S +   +   L     L  IQ+D
Sbjct: 68  GYNLMQAMRFAVEEINNDSSLLPGVLLGYEIVDVCYISNNVQPVLYFLAHEDNLLPIQED 127

Query: 131 TSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDR 190
            S+               +VV VIG   S   + VAN L LF +PQI+Y++ + EL D  
Sbjct: 128 YSNYI------------SRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKV 175

Query: 191 RYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYG-EKGVESFTQISKEAGGLC 249
           R+    R  P      +AMV ++    WN++  L S  +YG + G     ++++    +C
Sbjct: 176 RFPALLRTTPSADHHIEAMVQLMLHFRWNWIIVLVSSDTYGRDNGQLLGERVARR--DIC 233

Query: 250 IAQSVRIPQERKDRTIDFDR-----IIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQ 304
           IA    +P  + ++ +  +       I   L    +R VV+F+ D  +        R + 
Sbjct: 234 IAFQETLPTLQPNQNMTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYHFFNEVLRQNF 293

Query: 305 VGHFLWVGSDSWGSKINP-LHQHEDIAEGA----ITIQPKRATVEGFDAYFTSRTLENNR 359
            G  +W+ S+SW   I+P LH   ++        ITIQ     + GF  +          
Sbjct: 294 TGA-VWIASESWA--IDPVLHNLTELRHLGTFLGITIQS--VPIPGFSEFREWGPQAGPP 348

Query: 360 RNVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMA 419
                ++ +  N  C   ++ +   +T  + +G ER+           V  V  AVYA+A
Sbjct: 349 PLSRTSQSYTCNQECDNCLNATLSFNTILRLSG-ERV-----------VYSVYSAVYAVA 396

Query: 420 HALHHM---NKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGR 476
           HALH +   +K  C   R V P        +LL+ I  VNF       + F+  GD    
Sbjct: 397 HALHSLLGCDKSTCTK-RVVYPW-------QLLEEIWKVNFT-LLDHQIFFDPQGDVALH 447

Query: 477 YDIFQYQTTNTSNPGYRLIGQWTDELQL-NIEDMQWGKGVREIPASVCTLPCKPGQRKKT 535
            +I Q+Q   + NP   +   +  + QL NI+D+ W      IP S+C+  C+ GQ+KK 
Sbjct: 448 LEIVQWQWDRSQNPFQSVASYYPLQRQLKNIQDISWHTINNTIPMSMCSKRCQSGQKKKP 507

Query: 536 QKGTPCCWTCEPC---DGYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAV 592
                CC+ C  C       +  DE  CQ CP ++   ++ T C    ++ LEWH    +
Sbjct: 508 VGIHVCCFECIDCLPGTFLNHTEDEYECQACPNNEWSYQSETSCFKRQLVFLEWHEAPTI 567

Query: 593 IPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDV 652
               LA LG ++T+ ++  F R+  TPIVR++G  + +++LT + + Y++  + +  P V
Sbjct: 568 AVALLAALGFLSTLAILVIFWRHFQTPIVRSAGGPMCFLMLTLLLVAYMVVPVYVGPPKV 627

Query: 653 AVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTA----PRLISPTSQLAITSS 708
           + C  R+    L   I  + +  ++ +I   F+   +   A     R   P   +A  + 
Sbjct: 628 STCLCRQALFPLCFTICISCIAVRSFQIVCAFKMASRFPRAYSYWVRYQGPYVSMAFITV 687

Query: 709 LISVQLLGVFIWFGVDPPNIIIDYDEHK----TMNPEQARGVLKCDITDLQIICSLGYSI 764
           L  V ++   +  G+  P    D D+ K    + NP     +L     DL          
Sbjct: 688 LKMVIVVIGMLATGLS-PTTRTDPDDPKITIVSCNPNYRNSLLFNTSLDL---------- 736

Query: 765 LLMVTCTVYAIKTRGVPENFNEAKPIGFTM---YTTCIVWLAFIPIFFGTAQSAEKLYIQ 821
           LL V    +A   + +P N+NEAK I  +M   +T+ +    F+  + G   +   L + 
Sbjct: 737 LLSVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTSSVSLCTFMSAYSGVLVTIVDLLVT 796

Query: 822 TTTLTISMNLSASVALGMLYMPKVYIIIFHPELN 855
              L        +++LG  + PK Y+I+F+PE N
Sbjct: 797 VLNL-------LAISLG-YFGPKCYMILFYPERN 822


>gi|112807234 G protein-coupled receptor, family C, group 6, member
           A [Homo sapiens]
          Length = 926

 Score =  230 bits (587), Expect = 4e-60
 Identities = 220/857 (25%), Positives = 379/857 (44%), Gaps = 90/857 (10%)

Query: 47  GDVTLGGLFPVHAK---------GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLP 97
           G + +GGLF +H K          P    C   +    +  L AM+++++ IN+   LLP
Sbjct: 34  GHIIIGGLFAIHEKMLSSEDSPRRPQIQECVGFEISVFLQTL-AMIHSIEMINNS-TLLP 91

Query: 98  NVTLGARILDTCSRDTYALEQSLTFVQAL-IQKDTSDVRCTNGEPPVFVKPEKVVGVIGA 156
            V LG  I DTC+  T A+  +L F+      ++T + +C        VK      VIG+
Sbjct: 92  GVKLGYEIYDTCTEVTVAMAATLRFLSKFNCSRETVEFKCDYSSYMPRVK-----AVIGS 146

Query: 157 SGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKAL 216
             S +++ V+ +L L  +PQ+ Y STA  LSD  R+  F R VP D  Q +AM  +++  
Sbjct: 147 GYSEITMAVSRMLNLQLMPQVGYESTAEILSDKIRFPSFLRTVPSDFHQIKAMAHLIQKS 206

Query: 217 GWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTID--FDRIIKQL 274
           GWN++  + ++  YG   + +F  I  EA  +CIA    +P    D TI+   +R +K++
Sbjct: 207 GWNWIGIITTDDDYGRLALNTFI-IQAEANNVCIAFKEVLPAFLSDNTIEVRINRTLKKI 265

Query: 275 LDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGS--KINPLHQHEDIAEG 332
           +       +V+F     +  +    K  +   + +W+ SD+W +  KI  +   + I + 
Sbjct: 266 ILEAQVNVIVVFLRQFHVFDLFN--KAIEMNINKMWIASDNWSTATKITTIPNVKKIGK- 322

Query: 333 AITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEENFNCKLTISGSKKEDTD-RKCT 391
            +    +R  +  F ++  +  L  +  +    EY      C         +DTD  +C 
Sbjct: 323 VVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMHLSACAYV------KDTDLSQCI 376

Query: 392 ---GQERIGKDSN----------------YEQEGKVQFVIDAVYAMAHALHHMNKDLCAD 432
               Q  +   +N                Y + G +  +  AV+A+ +A+    +DLC  
Sbjct: 377 FNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVFALGYAI----RDLCQA 432

Query: 433 YRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGY 492
                P   Q    +LL  ++NV F     +   F+ +GD    YD+  ++  N    G+
Sbjct: 433 RDCQNPNAFQPW--ELLGVLKNVTFTDGWNS-FHFDAHGDLNTGYDVVLWKEIN----GH 485

Query: 493 RLIGQWTD-ELQLN---IEDMQWGKGVREIPA--SVCTLPCKPGQRKKTQKGTP-CCWTC 545
             + +  + +LQ +   I D +     R +    S C+  C PGQ KKT +    CC+ C
Sbjct: 486 MTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHICCYEC 545

Query: 546 EPC--DGYQYQFDEMTCQHCPYDQRPNENR-TGCQDIPIIKLEWHSPWAVIPVFLAMLGI 602
           + C  + Y  Q D   C  C         R T C +  +  L W+   A++ + L++LGI
Sbjct: 546 QNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGI 605

Query: 603 IATIFVMATFIRYNDTPIVRAS-GRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVF 661
           I  + V   F R  +TP+V++S G  + YV+L   FL +  T   I +P    C  R+  
Sbjct: 606 IFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTM 665

Query: 662 LGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIWF 721
            G+   +  + +LTK+ +I   F    K     + +     + I  +   +Q++   +W 
Sbjct: 666 FGVSFTLCISCILTKSLKILLAFSFDPKLQKFLKCL--YRPILIIFTCTGIQVVICTLWL 723

Query: 722 GVDPPNIIIDYDEHKTMNPEQARGVLKCDI-TDLQIICSLGYSILLMVTCTVYAIKTRGV 780
               P + ++    + +       +L+C+  + L     LGY  +L   C ++A K  G 
Sbjct: 724 IFAAPTVEVNVSLPRVI-------ILECEEGSILAFGTMLGYIAILAFICFIFAFK--GK 774

Query: 781 PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML 840
            EN+NEAK I F M    I W+ FIPI+  T       Y+    + + + +S    L   
Sbjct: 775 YENYNEAKFITFGMLIYFIAWITFIPIYATTFGK----YVPAVEIIVIL-ISNYGILYCT 829

Query: 841 YMPKVYIIIFHPELNVQ 857
           ++PK Y+II   E+N +
Sbjct: 830 FIPKCYVIICKQEINTK 846


>gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]
          Length = 852

 Score =  209 bits (531), Expect = 1e-53
 Identities = 207/872 (23%), Positives = 371/872 (42%), Gaps = 89/872 (10%)

Query: 20  VLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGV--------PCGDIK 71
           VL + L AL     G  +     +R++GD  LGGLFP+     +G+        P     
Sbjct: 6   VLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRF 65

Query: 72  RENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDT 131
             NG+    AM  A+++IN+  +LLP + LG  + DTCS    A++ SL F+     +D 
Sbjct: 66  SSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDI 125

Query: 132 SDV-RCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDR 190
           +     T  +P       +V+ VIG   S ++++       F +PQ+SY ++   LS   
Sbjct: 126 AAYCNYTQYQP-------RVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARE 178

Query: 191 RYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCI 250
            +  F R VP D  Q  A  ++++  GWN+V+ L S+  YG +G+  F+ ++  A G+CI
Sbjct: 179 TFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALA-AARGICI 237

Query: 251 AQSVRIPQERKD--RTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHF 308
           A    +P  R D  R      ++ Q+    +S  VV+          L     + ++   
Sbjct: 238 AHEGLVPLPRADDSRLGKVQDVLHQV--NQSSVQVVLLFASVHAAHALFNYSISSRLSPK 295

Query: 309 LWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYW 368
           +WV S++W +         D+  G +    +  TV GF        L+   +   F +Y 
Sbjct: 296 VWVASEAWLT--------SDLVMG-LPGMAQMGTVLGF--------LQRGAQLHEFPQYV 338

Query: 369 EENFNCK-----LTISGSKKEDTDRKCTGQ----------ERIGKDSNYEQEGKVQFVID 413
           + +          +  G +++  +    GQ          + +    N+ Q      V  
Sbjct: 339 KTHLALATDPAFCSALGEREQGLEEDVVGQRCPQCDCITLQNVSAGLNHHQTFS---VYA 395

Query: 414 AVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDA 473
           AVY++A ALH+    L  +  G CP  +     +LL+ + N+ F+   G P+ F+ +G+ 
Sbjct: 396 AVYSVAQALHN---TLQCNASG-CPAQDPVKPWQLLENMYNLTFH-VGGLPLRFDSSGNV 450

Query: 474 PGRYDIFQYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRK 533
              YD+ +      S P    +G++   L+     ++W     + P S C+  C+ GQ +
Sbjct: 451 DMEYDL-KLWVWQGSVPRLHDVGRFNGSLRTERLKIRWHTSDNQKPVSRCSRQCQEGQVR 509

Query: 534 KTQKGTPCCWTCEPCD--GYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWA 591
           + +    CC+ C  C+   Y+   D++ C  C  D+   E  T C       L W  P  
Sbjct: 510 RVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAWGEPAV 569

Query: 592 VIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPD 651
           ++ + L  L +   +  +  F+ + D+P+V+ASG  L+   L  + L  +   L   +P 
Sbjct: 570 LLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGLVCLGLVCLSVLLFPGQPS 629

Query: 652 VAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLI----SPTSQLAI-T 706
            A C  ++    L +    + L  +   I+   E       A RL      P + L +  
Sbjct: 630 PARCLAQQPLSHLPLTGCLSTLFLQAAEIF--VESELPLSWADRLSGCLRGPWAWLVVLL 687

Query: 707 SSLISVQLLGVFIWFGVD-PPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGY--S 763
           + L+ V L     W+ V  PP ++ D+     M P +A  ++ C  T   +   L +  +
Sbjct: 688 AMLVEVALC---TWYLVAFPPEVVTDWH----MLPTEA--LVHCR-TRSWVSFGLAHATN 737

Query: 764 ILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTT 823
             L   C +     R  P  +N A+ + F M    I W++F+P+         ++ ++  
Sbjct: 738 ATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLLANV-----QVVLRPA 792

Query: 824 TLTISMNLSASVALGMLYMPKVYIIIFHPELN 855
               ++ L     L   ++P+ Y+++  P LN
Sbjct: 793 VQMGALLLCVLGILAAFHLPRCYLLMRQPGLN 824


>gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo
           sapiens]
          Length = 254

 Score =  207 bits (526), Expect = 5e-53
 Identities = 113/234 (48%), Positives = 150/234 (64%), Gaps = 10/234 (4%)

Query: 642 ITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTS 701
           +TF+ IAKP  AVC+ RR+ LG    + Y+ALLTKTNRI RIF   ++    PR ISP S
Sbjct: 1   MTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPAS 60

Query: 702 QLAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGV-LKCDITDLQIICSL 760
           Q+AI  +LIS QLL V  W  V+ P         K   PE+   V L+C+  D  ++ SL
Sbjct: 61  QVAICLALISGQLLIVVAWLVVEAPGT------GKETAPERREVVTLRCNHRDASMLGSL 114

Query: 761 GYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYI 820
            Y++LL+  CT+YA KTR  PENFNEAK IGFTMYTTCI+WLAF+PIF+ T+       +
Sbjct: 115 AYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYR---V 171

Query: 821 QTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSS 874
           QTTT+ +S++LS SV LG L+ PK++II+F P+ NV   +       +AA  +S
Sbjct: 172 QTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAARAS 225


>gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens]
          Length = 841

 Score =  202 bits (515), Expect = 9e-52
 Identities = 210/865 (24%), Positives = 361/865 (41%), Gaps = 88/865 (10%)

Query: 23  VLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHA------KGPSGVPCGDIK--REN 74
           ++ C  A A    E  +     + GD  L GLFP+H+        P    C       E+
Sbjct: 14  LISCCWAFACHSTE--SSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEH 71

Query: 75  GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCS--RDTYALEQSLTFV---QALIQK 129
           G H  +AM   +++IN+   LLPN+TLG ++ D CS   + YA  + L+        +Q 
Sbjct: 72  GYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQG 131

Query: 130 DTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDD 189
           D      T            V+ VIG   ++ +   A +L  F +P ISYA+++  LS  
Sbjct: 132 DLLHYSPT------------VLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVK 179

Query: 190 RRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLC 249
           R+Y  F R +P D +Q + MV +++  GW ++S + S   YG+ GV++         G+C
Sbjct: 180 RQYPSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSDDYGQLGVQALEN-QATGQGIC 238

Query: 250 IAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFL 309
           IA    +P   +        +++ L     +  VV+F++ +  +    +    +  G  +
Sbjct: 239 IAFKDIMPFSAQVGDERMQCLMRHLAQA-GATVVVVFSSRQLARVFFESVVLTNLTGK-V 296

Query: 310 WVGSDSWGSKINPLHQHEDIAEG------AITIQPKRATVEGFDAYFTSRTLENNR--RN 361
           WV S++W      L +H     G       + +  ++  V G  A+  +    + +  R 
Sbjct: 297 WVASEAWA-----LSRHITGVPGIQRIGMVLGVAIQKRAVPGLKAFEEAYARADKKAPRP 351

Query: 362 VWFAEYWEENFNCKLTISGSKKEDTDRKCTG--QERIGKDSNYEQEGKVQFVIDAVYAMA 419
                +   N  C             R+C       + K   +           AVYA+A
Sbjct: 352 CHKGSWCSSNQLC-------------RECQAFMAHTMPKLKAFSMSSAYN-AYRAVYAVA 397

Query: 420 HALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDI 479
           H LH +    CA   G C    +    +LL+ I  V+F     T V FN N D    Y+I
Sbjct: 398 HGLHQLLG--CAS--GACSR-GRVYPWQLLEQIHKVHFLLHKDT-VAFNDNRDPLSSYNI 451

Query: 480 FQYQTTNTSNPGYRLIGQWT-DELQLNIED--MQWGKGVREIPASVCTLPCKPGQRKKTQ 536
             +   N     + ++G  T   +QLNI +  +QW     ++P SVC+  C  G ++   
Sbjct: 452 IAWDW-NGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT 510

Query: 537 KGTPCCWTCEPCDG--YQYQFDEMTCQHCPYDQRPNENRTGC--QDIPIIKLEWHSPWAV 592
               CC+ C PC    +  + D   CQ C  ++   E    C  + +  + L  H+ W +
Sbjct: 511 GFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVL 570

Query: 593 IPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDV 652
           +     +L  +  +     F  + DTP+VR++G  L +++L  +       +    +P  
Sbjct: 571 LAANTLLL--LLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTR 628

Query: 653 AVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLIS- 711
             C  R+    LG  I  + L  ++ ++  IF+   K  T            +   + S 
Sbjct: 629 PACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLFVMISSA 688

Query: 712 VQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITD-LQIICSLGYSILLMVTC 770
            QLL    W  V  P    +Y     +       +L+C  T+ L  I +  Y+ LL ++ 
Sbjct: 689 AQLLICLTWLVVWTPLPAREYQRFPHL------VMLECTETNSLGFILAFLYNGLLSISA 742

Query: 771 TVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMN 830
              +   + +PEN+NEAK + F++    + W+A    FF TA   +  Y+    +   ++
Sbjct: 743 FACSYLGKDLPENYNEAKCVTFSLLFNFVSWIA----FFTTASVYDGKYLPAANMMAGLS 798

Query: 831 LSASVALGMLYMPKVYIIIFHPELN 855
            S S   G  ++PK Y+I+  P+LN
Sbjct: 799 -SLSSGFGGYFLPKCYVILCRPDLN 822


>gi|29294619 sweet taste receptor T1r isoform c [Homo sapiens]
          Length = 587

 Score =  116 bits (291), Expect = 8e-26
 Identities = 104/417 (24%), Positives = 180/417 (43%), Gaps = 24/417 (5%)

Query: 448 LLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGYRLIGQWT-DELQLNI 506
           LL+ I  V+F     T V FN N D    Y+I  +   N     + ++G  T   +QLNI
Sbjct: 167 LLEQIHKVHFLLHKDT-VAFNDNRDPLSSYNIIAWDW-NGPKWTFTVLGSSTWSPVQLNI 224

Query: 507 ED--MQWGKGVREIPASVCTLPCKPGQRKKTQKGTPCCWTCEPCDG--YQYQFDEMTCQH 562
            +  +QW     ++P SVC+  C  G ++       CC+ C PC    +  + D   CQ 
Sbjct: 225 NETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQP 284

Query: 563 CPYDQRPNENRTGC--QDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPI 620
           C  ++   E    C  + +  + L  H+ W ++     +L  +  +     F  + DTP+
Sbjct: 285 CGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLL--LLLLGTAGLFAWHLDTPV 342

Query: 621 VRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRI 680
           VR++G  L +++L  +       +    +P    C  R+    LG  I  + L  ++ ++
Sbjct: 343 VRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQL 402

Query: 681 YRIFEQGKKSVTAPRLISPTSQLAITSSLIS-VQLLGVFIWFGVDPPNIIIDYDEHKTMN 739
             IF+   K  T            +   + S  QLL    W  V  P    +Y     + 
Sbjct: 403 IIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHL- 461

Query: 740 PEQARGVLKCDITD-LQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTC 798
                 +L+C  T+ L  I +  Y+ LL ++    +   + +PEN+NEAK + F++    
Sbjct: 462 -----VMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNF 516

Query: 799 IVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELN 855
           + W+A    FF TA   +  Y+    +   ++ S S   G  ++PK Y+I+  P+LN
Sbjct: 517 VSWIA----FFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCRPDLN 568



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 10/96 (10%)

Query: 23  VLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHA------KGPSGVPCGDIK--REN 74
           ++ C  A A    E  +     + GD  L GLFP+H+        P    C       E+
Sbjct: 14  LISCCWAFACHSTE--SSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEH 71

Query: 75  GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCS 110
           G H  +AM   +++IN+   LLPN+TLG ++ D CS
Sbjct: 72  GYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCS 107


>gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens]
          Length = 480

 Score =  105 bits (263), Expect = 1e-22
 Identities = 82/307 (26%), Positives = 141/307 (45%), Gaps = 30/307 (9%)

Query: 23  VLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHA------KGPSGVPCGDIK--REN 74
           ++ C  A A    E  +     + GD  L GLFP+H+        P    C       E+
Sbjct: 14  LISCCWAFACHSTE--SSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEH 71

Query: 75  GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCS--RDTYALEQSLTFV---QALIQK 129
           G H  +AM   +++IN+   LLPN+TLG ++ D CS   + YA  + L+        +Q 
Sbjct: 72  GYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQG 131

Query: 130 DTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDD 189
           D      T            V+ VIG   ++ +   A +L  F +P ISYA+++  LS  
Sbjct: 132 DLLHYSPT------------VLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVK 179

Query: 190 RRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLC 249
           R+Y  F R +P D +Q + MV +++  GW ++S + S   YG+ GV++  +      G+C
Sbjct: 180 RQYPSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSDDYGQLGVQAL-ENQATGQGIC 238

Query: 250 IAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFL 309
           IA    +P   +        +++ L     +  VV+F++ +  +    +    +  G  +
Sbjct: 239 IAFKDIMPFSAQVGDERMQCLMRHLAQA-GATVVVVFSSRQLARVFFESVVLTNLTGK-V 296

Query: 310 WVGSDSW 316
           WV S++W
Sbjct: 297 WVASEAW 303


>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
          Length = 941

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 64/284 (22%), Positives = 127/284 (44%), Gaps = 26/284 (9%)

Query: 597 LAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFL-------MIAK 649
           L +LG+I     +   I+  +  +++ S   ++ +++ G  L Y   FL       +  K
Sbjct: 488 LTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEK 547

Query: 650 PDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSL 709
               +C+ R   L +G   ++ A+  KT R++ IF+  K      ++I     L I   +
Sbjct: 548 TFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMK---KKIIKDQKLLVIVGGM 604

Query: 710 ISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQA------RGVLK-CDITDLQIICSLGY 762
           + + L  +  W  VDP    +   E  +M P+ A      R +L+ C+ T + I   + Y
Sbjct: 605 LLIDLCILICWQAVDPLRRTV---EKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVY 661

Query: 763 SI--LLMVTCTVYAIKTRGVP-ENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLY 819
           +   LLM+     A +TR V     N++K IG ++Y   I+ +    + F T        
Sbjct: 662 AYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPN--- 718

Query: 820 IQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSF 863
           +Q   + + +   +++ L ++++PK+  +  +P+   Q R+  F
Sbjct: 719 VQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQF 762



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 64/248 (25%), Positives = 110/248 (44%), Gaps = 43/248 (17%)

Query: 9   RVLTLMKFPCCVLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCG 68
           R+L L+  P      LL  LA  A G    AP        +++ GL P+  +    V  G
Sbjct: 22  RLLLLLLLP------LLLPLAPGAWGWARGAPRPPPSSPPLSIMGLMPLTKE----VAKG 71

Query: 69  DIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQ 128
            I R  G+  L A+  A++QI ++  L P   L  R+ DT   +   L+    F  A   
Sbjct: 72  SIGR--GV--LPAVELAIEQIRNESLLRPYF-LDLRLYDTECDNAKGLK---AFYDA--- 120

Query: 129 KDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSD 188
                         +   P  ++ V G    SV+ ++A  L+ + + Q+S+A+T P L+D
Sbjct: 121 --------------IKYGPNHLM-VFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLAD 165

Query: 189 DRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGL 248
            ++Y +F R VP D+    A++ ++K   W  V TL  +       V+ F+++  +  G+
Sbjct: 166 KKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQD-------VQRFSEVRNDLTGV 218

Query: 249 CIAQSVRI 256
              + + I
Sbjct: 219 LYGEDIEI 226


>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
           precursor [Homo sapiens]
          Length = 899

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 53/208 (25%), Positives = 88/208 (42%), Gaps = 37/208 (17%)

Query: 40  PHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNV 99
           PHS R    V +G LFP+    P G  C             A+  AL+ +NS  ++LP+ 
Sbjct: 101 PHSERRA--VYIGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDY 147

Query: 100 TLGARILDT-CSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASG 158
            L     D+ C        Q+  ++  L+  D                P K++ + G S 
Sbjct: 148 ELKLIHHDSKCDPG-----QATKYLYELLYND----------------PIKIILMPGCS- 185

Query: 159 SSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGW 218
            SVS +VA   R++ +  +SY S++P LS+ +R+  F R  P  +      V + +  GW
Sbjct: 186 -SVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 244

Query: 219 NYVSTLASEGSYGEKGVESFTQISKEAG 246
             ++T+          ++   +  KEAG
Sbjct: 245 KKIATIQQTTEVFTSTLDDLEERVKEAG 272



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 57/276 (20%), Positives = 114/276 (41%), Gaps = 27/276 (9%)

Query: 597 LAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLM------IAKP 650
           L+ LGI+  +  ++  I  +    ++ S   L+ +   G  L     F +      I + 
Sbjct: 536 LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN 595

Query: 651 DVA-VCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSL 709
               VC  R   LGLG  + Y ++ TK   ++ +F + ++     + + P    A    L
Sbjct: 596 QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL 655

Query: 710 ISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICS---------- 759
           + + +L + IW  VDP +  I+     T   E+ +  +   I      CS          
Sbjct: 656 VGMDVLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGI 710

Query: 760 -LGYSILLMVTCTVYAIKTRGV-PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEK 817
             GY  LL++     A +T+ V  E  N+ + +G  +Y   ++ L   P+    +   + 
Sbjct: 711 FYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDA 770

Query: 818 LYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPE 853
            +      ++++  S+ + L +L++PK+  +I   E
Sbjct: 771 AF---AFASLAIVFSSYITLVVLFVPKMRRLITRGE 803


>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
           precursor [Homo sapiens]
          Length = 844

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 51/208 (24%), Positives = 86/208 (41%), Gaps = 35/208 (16%)

Query: 40  PHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNV 99
           PH       V +G LFP+    P G  C             A+  AL+ +NS  ++LP+ 
Sbjct: 44  PHPSSERRAVYIGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDY 92

Query: 100 TLGARILDT-CSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASG 158
            L     D+ C        Q+  ++  L+  D                P K++ + G S 
Sbjct: 93  ELKLIHHDSKCDPG-----QATKYLYELLYND----------------PIKIILMPGCS- 130

Query: 159 SSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGW 218
            SVS +VA   R++ +  +SY S++P LS+ +R+  F R  P  +      V + +  GW
Sbjct: 131 -SVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 189

Query: 219 NYVSTLASEGSYGEKGVESFTQISKEAG 246
             ++T+          ++   +  KEAG
Sbjct: 190 KKIATIQQTTEVFTSTLDDLEERVKEAG 217



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 57/276 (20%), Positives = 114/276 (41%), Gaps = 27/276 (9%)

Query: 597 LAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLM------IAKP 650
           L+ LGI+  +  ++  I  +    ++ S   L+ +   G  L     F +      I + 
Sbjct: 481 LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN 540

Query: 651 DVA-VCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSL 709
               VC  R   LGLG  + Y ++ TK   ++ +F + ++     + + P    A    L
Sbjct: 541 QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL 600

Query: 710 ISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICS---------- 759
           + + +L + IW  VDP +  I+     T   E+ +  +   I      CS          
Sbjct: 601 VGMDVLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGI 655

Query: 760 -LGYSILLMVTCTVYAIKTRGV-PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEK 817
             GY  LL++     A +T+ V  E  N+ + +G  +Y   ++ L   P+    +   + 
Sbjct: 656 FYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDA 715

Query: 818 LYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPE 853
            +      ++++  S+ + L +L++PK+  +I   E
Sbjct: 716 AF---AFASLAIVFSSYITLVVLFVPKMRRLITRGE 748


>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
           precursor [Homo sapiens]
          Length = 961

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 53/208 (25%), Positives = 88/208 (42%), Gaps = 37/208 (17%)

Query: 40  PHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNV 99
           PHS R    V +G LFP+    P G  C             A+  AL+ +NS  ++LP+ 
Sbjct: 163 PHSERRA--VYIGALFPMSGGWPGGQACQP-----------AVEMALEDVNSRRDILPDY 209

Query: 100 TLGARILDT-CSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASG 158
            L     D+ C        Q+  ++  L+  D                P K++ + G S 
Sbjct: 210 ELKLIHHDSKCDPG-----QATKYLYELLYND----------------PIKIILMPGCS- 247

Query: 159 SSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGW 218
            SVS +VA   R++ +  +SY S++P LS+ +R+  F R  P  +      V + +  GW
Sbjct: 248 -SVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGW 306

Query: 219 NYVSTLASEGSYGEKGVESFTQISKEAG 246
             ++T+          ++   +  KEAG
Sbjct: 307 KKIATIQQTTEVFTSTLDDLEERVKEAG 334



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 57/276 (20%), Positives = 114/276 (41%), Gaps = 27/276 (9%)

Query: 597 LAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLM------IAKP 650
           L+ LGI+  +  ++  I  +    ++ S   L+ +   G  L     F +      I + 
Sbjct: 598 LSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRN 657

Query: 651 DVA-VCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSL 709
               VC  R   LGLG  + Y ++ TK   ++ +F + ++     + + P    A    L
Sbjct: 658 QFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL 717

Query: 710 ISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICS---------- 759
           + + +L + IW  VDP +  I+     T   E+ +  +   I      CS          
Sbjct: 718 VGMDVLTLAIWQIVDPLHRTIE-----TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGI 772

Query: 760 -LGYSILLMVTCTVYAIKTRGV-PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEK 817
             GY  LL++     A +T+ V  E  N+ + +G  +Y   ++ L   P+    +   + 
Sbjct: 773 FYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDA 832

Query: 818 LYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPE 853
            +      ++++  S+ + L +L++PK+  +I   E
Sbjct: 833 AF---AFASLAIVFSSYITLVVLFVPKMRRLITRGE 865


>gi|29294621 sweet taste receptor T1r isoform d [Homo sapiens]
          Length = 324

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 10/96 (10%)

Query: 23  VLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHA------KGPSGVPCGDIK--REN 74
           ++ C  A A    E  +     + GD  L GLFP+H+        P    C       E+
Sbjct: 14  LISCCWAFACHSTE--SSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEH 71

Query: 75  GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCS 110
           G H  +AM   +++IN+   LLPN+TLG ++ D CS
Sbjct: 72  GYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCS 107



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 40/136 (29%), Positives = 59/136 (43%), Gaps = 11/136 (8%)

Query: 448 LLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGYRLIGQWT-DELQLNI 506
           LL+ I  V+F     T V FN N D    Y+I  +   N     + ++G  T   +QLNI
Sbjct: 167 LLEQIHKVHFLLHKDT-VAFNDNRDPLSSYNIIAWDW-NGPKWTFTVLGSSTWSPVQLNI 224

Query: 507 ED--MQWGKGVREIPASVCTLPCKPGQRKKTQKGTPCCWTCEPCDGYQYQFDE----MTC 560
            +  +QW     ++P SVC+  C  G ++       CC+ C PC    +         TC
Sbjct: 225 NETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSATWVRTC 284

Query: 561 QHCPYDQRPNENRTGC 576
           Q      RPN + + C
Sbjct: 285 QRT--TTRPNVSPSAC 298


>gi|7706451 G protein-coupled receptor, family C, group 5, member B
           precursor [Homo sapiens]
          Length = 403

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 53/269 (19%), Positives = 111/269 (41%), Gaps = 42/269 (15%)

Query: 590 WAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRE----LSYVLLTGIFLCYIITFL 645
           W ++   +A  G + T+ +M   I     P ++   ++    L ++ L G    + +TF 
Sbjct: 55  WGIVVEAVAGAGALITLLLM--LILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFA 112

Query: 646 MIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAP---RLISPTSQ 702
            I + D  +CS RR   G+   + ++ LL++  R+ R+   G    T P   +L+     
Sbjct: 113 FIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHG----TGPAGWQLVGLALC 168

Query: 703 LAITSSLISVQLLGVFIWFGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGY 762
           L +   +I+V+ L + +     P                       C    +  + +L Y
Sbjct: 169 LMLVQVIIAVEWLVLTVLRDTRP----------------------ACAYEPMDFVMALIY 206

Query: 763 SILLMVTCTVYAIKTRGVPENFNEAKPIG----FTMYTTCIVWLAFIPIF-FGTAQSAEK 817
            ++L+V     A+ T  +   F   K  G     T + + ++W+A++ ++ FG  +  + 
Sbjct: 207 DMVLLVVTLGLALFT--LCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQG 264

Query: 818 LYIQTTTLTISMNLSASVALGMLYMPKVY 846
                 TL I++  S  V +    +P+++
Sbjct: 265 DAWNDPTLAITLAASGWVFVIFHAIPEIH 293


>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
          Length = 885

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 27/147 (18%), Positives = 63/147 (42%), Gaps = 19/147 (12%)

Query: 172 FQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYG 231
           ++IP +   +     SD   +  F R VPP S Q+    ++++   WN++  L S+   G
Sbjct: 114 YRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEG 173

Query: 232 EKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFD----RIIKQLLDTP--NSRAVVI 285
               +    + +E             + + ++ + FD     +   L++     +R +++
Sbjct: 174 RAAQKRLETLLEER------------ESKAEKVLQFDPGTKNVTALLMEAKELEARVIIL 221

Query: 286 FANDEDIKQILAAAKRADQVGH-FLWV 311
            A+++D   +  AA   +  G  ++W+
Sbjct: 222 SASEDDAATVYRAAAMLNMTGSGYVWL 248


>gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]
          Length = 938

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 27/147 (18%), Positives = 63/147 (42%), Gaps = 19/147 (12%)

Query: 172 FQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYG 231
           ++IP +   +     SD   +  F R VPP S Q+    ++++   WN++  L S+   G
Sbjct: 114 YRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEG 173

Query: 232 EKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFD----RIIKQLLDTP--NSRAVVI 285
               +    + +E             + + ++ + FD     +   L++     +R +++
Sbjct: 174 RAAQKRLETLLEER------------ESKAEKVLQFDPGTKNVTALLMEAKELEARVIIL 221

Query: 286 FANDEDIKQILAAAKRADQVGH-FLWV 311
            A+++D   +  AA   +  G  ++W+
Sbjct: 222 SASEDDAATVYRAAAMLNMTGSGYVWL 248


>gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]
          Length = 901

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 27/147 (18%), Positives = 63/147 (42%), Gaps = 19/147 (12%)

Query: 172 FQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYG 231
           ++IP +   +     SD   +  F R VPP S Q+    ++++   WN++  L S+   G
Sbjct: 114 YRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHEG 173

Query: 232 EKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFD----RIIKQLLDTP--NSRAVVI 285
               +    + +E             + + ++ + FD     +   L++     +R +++
Sbjct: 174 RAAQKRLETLLEER------------ESKAEKVLQFDPGTKNVTALLMEAKELEARVIIL 221

Query: 286 FANDEDIKQILAAAKRADQVGH-FLWV 311
            A+++D   +  AA   +  G  ++W+
Sbjct: 222 SASEDDAATVYRAAAMLNMTGSGYVWL 248


>gi|93352554 GPR158-like 1 [Homo sapiens]
          Length = 2367

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 66/301 (21%), Positives = 115/301 (38%), Gaps = 34/301 (11%)

Query: 558 MTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYND 617
           + C  CP      E  T C D     +E  +      +      ++A    M    R   
Sbjct: 354 LQCLPCP------EGCTSCMDATPCLVEEAAVLRAAVLACQACCMLAIFLSMLVSYRCRR 407

Query: 618 TPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKT 677
              + ASG  L   +L G  L Y   F++  KP V  C   R    LG  I Y  ++ K 
Sbjct: 408 NKRIWASGVVLLETVLFGFLLLYFPVFILYFKPSVFRCIALRWVRLLGFAIVYGTIILKL 467

Query: 678 NRIYRIFEQGKKSVTAPR-LISPTSQLAITSSLISVQLLG-VFIWF------GVDPPNII 729
            R+ ++F     S TA R  +  + +L     L+ + +LG + +W       G+    ++
Sbjct: 468 YRVLQLF----LSRTAQRSALLSSGRLLRRLGLLLLPVLGFLAVWTVGALERGIQHAPLV 523

Query: 730 IDYDEHKTMNPEQARGVLKC--DITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEA 787
           I        +    R    C  D  D  ++ +    +LL+   +     TR V   F+E 
Sbjct: 524 I------RGHTPSGRHFYLCHHDRWDYIMVVA---ELLLLCWGSFLCYATRAVLSAFHEP 574

Query: 788 KPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASV--ALGMLYMPKV 845
           + +G  ++   ++  AF    F    S   L+   T L    +  ++V   L ++++PK 
Sbjct: 575 RYMGIALHNELLLSAAFHTARFVLVPS---LHPDWTLLLFFFHTHSTVTTTLALIFIPKF 631

Query: 846 Y 846
           +
Sbjct: 632 W 632


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,811,417
Number of Sequences: 37866
Number of extensions: 1537069
Number of successful extensions: 3288
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 3124
Number of HSP's gapped (non-prelim): 65
length of query: 922
length of database: 18,247,518
effective HSP length: 112
effective length of query: 810
effective length of database: 14,006,526
effective search space: 11345286060
effective search space used: 11345286060
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.