Search of human proteins with 32401437

Search of human proteins with 32401437

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32401437 H1 histone family, member N, testis-specific [Homo
sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32401437 H1 histone family, member N, testis-specific [Homo s...   508   e-144
gi|4885373 histone cluster 1, H1a [Homo sapiens]                       65   4e-11
gi|4885379 histone cluster 1, H1e [Homo sapiens]                       65   6e-11
gi|4885381 histone cluster 1, H1b [Homo sapiens]                       64   2e-10
gi|4885377 histone cluster 1, H1d [Homo sapiens]                       62   6e-10
gi|4885375 histone cluster 1, H1c [Homo sapiens]                       60   2e-09
gi|20544168 histone cluster 1, H1t [Homo sapiens]                      52   5e-07
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          50   1e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        48   9e-06
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    47   2e-05
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     45   6e-05
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         45   8e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            44   1e-04
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap...    44   1e-04
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap...    44   1e-04
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        44   1e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            44   1e-04
gi|188536004 zinc finger protein 469 [Homo sapiens]                    44   2e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     43   2e-04
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    43   2e-04
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]          43   3e-04
gi|50962882 G patch domain containing 8 [Homo sapiens]                 43   3e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         43   3e-04
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    42   5e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     42   5e-04
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        42   7e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    41   9e-04
gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001
gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001
gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]            41   0.001

>gi|32401437 H1 histone family, member N, testis-specific [Homo
           sapiens]
          Length = 255

 Score =  508 bits (1308), Expect = e-144
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MEQALTGEAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRV 60
           MEQALTGEAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRV
Sbjct: 1   MEQALTGEAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRV 60

Query: 61  SQLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYF 120
           SQLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYF
Sbjct: 61  SQLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYF 120

Query: 121 RVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKA 180
           RVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKA
Sbjct: 121 RVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKA 180

Query: 181 KANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPR 240
           KANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPR
Sbjct: 181 KANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPR 240

Query: 241 EEKQEPKKPAQRTIQ 255
           EEKQEPKKPAQRTIQ
Sbjct: 241 EEKQEPKKPAQRTIQ 255


>gi|4885373 histone cluster 1, H1a [Homo sapiens]
          Length = 215

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 29/233 (12%)

Query: 14  PRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHK- 72
           P    + A  E P    +++  +     ++K   GPS         VS+L++QA S+ K 
Sbjct: 6   PPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPS---------VSELIVQAASSSKE 56

Query: 73  --GLTLAALKKELRNAGYEVRRKSGRHEAPRGQ--AKATLLRVSGSDAAGYFRV-WKVPK 127
             G++LAALKK L  AGY+V + + R +       +K TL++  G+ A+G F++  K   
Sbjct: 57  RGGVSLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASS 116

Query: 128 PRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARAR 187
              KPG ++    T+A      A +  ++     +K+ +  ++  +  A  K+  N +  
Sbjct: 117 VETKPGASKVATKTKA----TGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKP 172

Query: 188 RTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPR 240
           +T + +  AK P  A+A +   A A            T P++ K K+ + K +
Sbjct: 173 KTVKPKKVAKSPAKAKAVKPKAAKA----------RVTKPKTAKPKKAAPKKK 215


>gi|4885379 histone cluster 1, H1e [Homo sapiens]
          Length = 219

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 58/220 (26%), Positives = 103/220 (46%), Gaps = 40/220 (18%)

Query: 21  AMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHK---GLTLA 77
           A   AP P+ ++      +  A K+ G   R  S     VS+L+ +A++  K   G++LA
Sbjct: 7   AAPAAPAPAEKT----PVKKKARKSAGAAKRKASGPP--VSELITKAVAASKERSGVSLA 60

Query: 78  ALKKELRNAGYEVRRKSGRHEAPRGQ--AKATLLRVSGSDAAGYFRVWK----------- 124
           ALKK L  AGY+V + + R +       +K TL++  G+ A+G F++ K           
Sbjct: 61  ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA 120

Query: 125 --------------VPKPRRKPGRA---RQEEGTRAPWRTPAAPRSSRRRRQPLRKAARK 167
                           KP++  G A   +  + T    + PAA   +++ + P +  A K
Sbjct: 121 KKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKKAKAAK 180

Query: 168 AREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEE 207
            ++  +  A+AKA    +A + + A+P+A +P  A AK++
Sbjct: 181 PKKAPKSPAKAKA-VKPKAAKPKTAKPKAAKPKKAAAKKK 219



 Score = 28.5 bits (62), Expect = 5.9
 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 16/91 (17%)

Query: 176 ARAKAKANARARRTRRARPRAKEPPCARAKEEAGAT-AADEGRGQAVKEDT---TPRSGK 231
           A    K N +A  +  A+P+AK+   A+AK+ AGA     +  G A  + +   TP+  K
Sbjct: 101 ASGSFKLNKKAA-SGEAKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAK 159

Query: 232 -----------DKRRSSKPREEKQEPKKPAQ 251
                         + +K  + K+ PK PA+
Sbjct: 160 KPAAAAGAKKAKSPKKAKAAKPKKAPKSPAK 190


>gi|4885381 histone cluster 1, H1b [Homo sapiens]
          Length = 226

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 52/204 (25%), Positives = 98/204 (48%), Gaps = 31/204 (15%)

Query: 41  PAEKTVGGPSRGCSSSVLR-----VSQLVLQAISTHK---GLTLAALKKELRNAGYEVRR 92
           PA+K     + G  ++  +     VS+L+ +A++  K   GL+LAALKK L   GY+V +
Sbjct: 19  PAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAALKKALAAGGYDVEK 78

Query: 93  KSGRHEAPRGQ--AKATLLRVSGSDAAGYFRVWK-----VPKPR---------RKPGRAR 136
            + R +       +K TL++  G+ A+G F++ K       KP+         +KP  A 
Sbjct: 79  NNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAGAAKAKKPAGAT 138

Query: 137 QEEGTRAPWRTPAAPRSSRRRRQP-------LRKAARKAREVWRRNARAKAKANARARRT 189
            ++  +A     A  ++ ++ ++P       + K+ +KA+   +     K+ A  +A + 
Sbjct: 139 PKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKP 198

Query: 190 RRARPRAKEPPCARAKEEAGATAA 213
           + A+P+A +P  A+ K      AA
Sbjct: 199 KAAKPKAAKPKAAKPKAAKAKKAA 222



 Score = 32.3 bits (72), Expect = 0.41
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 18/91 (19%)

Query: 176 ARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAAD----EGRGQAVKE-------- 223
           A    K N +A  +  A+P+AK+   A+AK+ AGAT        G  +AVK+        
Sbjct: 104 ASGSFKLNKKAA-SGEAKPKAKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKP 162

Query: 224 -----DTTPRSGKDKRRSSKPREEKQEPKKP 249
                    +S K  + ++KP++  + P KP
Sbjct: 163 AAAGVKKVAKSPKKAKAAAKPKKATKSPAKP 193


>gi|4885377 histone cluster 1, H1d [Homo sapiens]
          Length = 221

 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 56/206 (27%), Positives = 103/206 (50%), Gaps = 40/206 (19%)

Query: 41  PAEKT--------VGGPSRGCSSSVLRVSQLVLQAISTHK---GLTLAALKKELRNAGYE 89
           PAEKT         G  +    +S   VS+L+ +A++  K   G++LAALKK L  AGY+
Sbjct: 14  PAEKTPVKKKAKKAGATAGKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYD 73

Query: 90  VRRKSGRHEAPRGQ--AKATLLRVSGSDAAGYFRVWK---------------VPKPRRKP 132
           V + + R +       +K TL++  G+ A+G F++ K                 KPR+  
Sbjct: 74  VEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKPKAKKAGAAKPRKPA 133

Query: 133 GRARQEE---GTRAPWRTPAAPRSSRRRRQP-----LRKAARKAREVWRRNAR--AKAKA 182
           G A++ +   G   P +  +  ++ ++ ++P      +K A+ A++V     +  AK+ A
Sbjct: 134 GAAKKPKKVAGAATPKK--SIKKTPKKVKKPATAAGTKKVAKSAKKVKTPQPKKAAKSPA 191

Query: 183 NARARRTRRARPRAKEPPCARAKEEA 208
            A+A + + A+P++ +P   +AK+ A
Sbjct: 192 KAKAPKPKAAKPKSGKPKVTKAKKAA 217


>gi|4885375 histone cluster 1, H1c [Homo sapiens]
          Length = 213

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 57/211 (27%), Positives = 102/211 (48%), Gaps = 31/211 (14%)

Query: 23  AEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHK---GLTLAAL 79
           A A  P  E    +  +  A K  GG  R  S     VS+L+ +A++  K   G++LAAL
Sbjct: 8   APAAAPPAEK---APVKKKAAKKAGGTPRKASGPP--VSELITKAVAASKERSGVSLAAL 62

Query: 80  KKELRNAGYEVRRKSGRHEAPRGQ--AKATLLRVSGSDAAGYFRVWK-----VPKPR--- 129
           KK L  AGY+V + + R +       +K TL++  G+ A+G F++ K       KP+   
Sbjct: 63  KKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKK 122

Query: 130 ------RKPGRARQEEGTRAPWRTP--AAPRSSRRRRQP-----LRKAARKAREVWRRNA 176
                 +KP  A ++    A   TP  +A ++ ++ ++P      +K A+  ++      
Sbjct: 123 AGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKP 182

Query: 177 RAKAKANARARRTRRARPRAKEPPCARAKEE 207
           +  AK+ A+A + + A+P+  +P  A  K++
Sbjct: 183 KKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK 213


>gi|20544168 histone cluster 1, H1t [Homo sapiens]
          Length = 207

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 54/196 (27%), Positives = 93/196 (47%), Gaps = 18/196 (9%)

Query: 22  MAEAPGPSGESRGHSATQ-LPAEKTVGGPSRGCSSSV----LRVSQLVLQAISTHK---G 73
           M+E    +  S G +A + LP +K    P+   S+S     L VS+L+ +A+S  +   G
Sbjct: 1   MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG 60

Query: 74  LTLAALKKELRNAGYEVRRKSGRHEAPRGQA--KATLLRVSGSDAAGYFRVWKVPKPRRK 131
           ++L ALKK L  AGY+V + + R +        K  L++  G+ A+G F++ K   P  K
Sbjct: 61  MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIP--K 118

Query: 132 PGRARQEEGTRAPWRTPAAPRSSRR-RRQPLRKAARKAREVWRRNARAKAKANARARRTR 190
             R++ ++   A  +     R S+  +     K A+K R    +  R+  KA     +  
Sbjct: 119 STRSKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAKKPRATTPKTVRSGRKA-----KGA 173

Query: 191 RARPRAKEPPCARAKE 206
           + + + K P  ARA +
Sbjct: 174 KGKQQQKSPVKARASK 189


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 61/260 (23%), Positives = 106/260 (40%), Gaps = 24/260 (9%)

Query: 9   AQSRWPRRGGSGAMAEAPG-------PSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVS 61
           +QSR PRR  SG+                 SR  S T+      +G  S+  S S  +  
Sbjct: 282 SQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQ 341

Query: 62  QLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFR 121
               Q+ +  +G +    +   +   +   R S +    RG +     + SG   +G   
Sbjct: 342 N---QSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPR--KESGRSQSGSPN 396

Query: 122 VWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAAR-----KAREVWRRNA 176
             +     R P +AR    +R+P++  A  RS  R     R  +R     KAR+  R  +
Sbjct: 397 KQRDHSRSRSPNKARDRSRSRSPYK--ARDRSRSRSPNKARDCSRSRSPYKARDRSRSRS 454

Query: 177 RAKAKANARARRTRRA--RPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKR 234
             KA+ ++R+R   +A  R R++ P   R   + G+ + +    ++ +  +  R  +  R
Sbjct: 455 PNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRS-RSPSKERQCRQSR 513

Query: 235 RSSKPREEK--QEPKKPAQR 252
            SSK R+ +  + P K  QR
Sbjct: 514 SSSKERDHRRSRSPSKERQR 533



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 27/120 (22%), Positives = 54/120 (45%), Gaps = 11/120 (9%)

Query: 129 RRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARR 188
           +R+  R+  +E  R+  R+P+  R  R+ R P ++  R+    WR  ++ + +  +R+  
Sbjct: 532 QRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRR---WRSPSKERERRQSRSSS 588

Query: 189 TRRARPRAKEP--------PCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPR 240
             R   R++ P        P A +KE+A + +    +     +  T     D  +S+ PR
Sbjct: 589 EERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPR 648



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 27/131 (20%), Positives = 50/131 (38%), Gaps = 17/131 (12%)

Query: 134 RARQEEGTRAPWRTPAAPRSSRRRRQPLRKA--------------ARKAREVWRRNARAK 179
           R  Q  GT +  RTP    S   +R P R +              A + R    +   ++
Sbjct: 110 RCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSR 169

Query: 180 AKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKP 239
            K+  R R + R R  ++        +++       G G++ +   TP + K +  +  P
Sbjct: 170 GKSYGRPRTSNRERSDSQP---RNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIP 226

Query: 240 REEKQEPKKPA 250
            +EK +   P+
Sbjct: 227 SKEKSDNPSPS 237


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 22/181 (12%)

Query: 84  RNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRA 143
           RN     R +S R      ++ AT  R      A   R  +   P R+  R+R     R+
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRS-RSRTPARRRSRSRTPTRRRS 604

Query: 144 PWRTPAAPRSSR---------RRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARP 194
             RTPA    SR         R R P+R+ +R +R   RR+ R++++  AR  R+R   P
Sbjct: 605 RSRTPARRGRSRSRTPARRRSRTRSPVRRRSR-SRSPARRSGRSRSRTPARRGRSRSRTP 663

Query: 195 RAK-----EPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRS--SKPREEKQEPK 247
             +       P  R+      T A  GR ++     TPR G+ + RS   + R   + P+
Sbjct: 664 ARRGRSRSRTPARRSGRSRSRTPARRGRSRS----RTPRRGRSRSRSLVRRGRSHSRTPQ 719

Query: 248 K 248
           +
Sbjct: 720 R 720



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 9/123 (7%)

Query: 130 RKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRT 189
           R P R R    +R P R  +  R+  RRR   R  AR+ R   R  AR +++  +  RR 
Sbjct: 576 RTPAR-RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRR 634

Query: 190 RRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKP 249
            R+R      P  R+      T A  GR    +  T  R G+ + R+   R  +   + P
Sbjct: 635 SRSR-----SPARRSGRSRSRTPARRGRS---RSRTPARRGRSRSRTPARRSGRSRSRTP 686

Query: 250 AQR 252
           A+R
Sbjct: 687 ARR 689



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 10/139 (7%)

Query: 123 WKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKA 182
           W   +  ++ GR+R     R+  R+PA  R   R R P R+   ++R   RR +R++   
Sbjct: 542 WSRSRNTQRRGRSRSARRGRSHSRSPAT-RGRSRSRTPARRGRSRSRTPARRRSRSRTPT 600

Query: 183 NARARR---TRRARPRAKEPPCARAKEEAGATAADEGRGQAVKED-----TTPRSGKDKR 234
             R+R     RR R R++ P   R++  +        R  A +       T  R G+ + 
Sbjct: 601 RRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRS 660

Query: 235 RSSKPREEKQEPKKPAQRT 253
           R+   R  +   + PA+R+
Sbjct: 661 RTPA-RRGRSRSRTPARRS 678



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 64/276 (23%), Positives = 114/276 (41%), Gaps = 40/276 (14%)

Query: 14   PRRGGSGAMAEAPGPSGES------------------RGHSATQLPAEKTVGGPSRGCSS 55
            PRR  SG+ ++  GPS E                   RG  ++  P  K+   P R  S 
Sbjct: 1633 PRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSR 1692

Query: 56   SVLRVSQLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSD 115
            S     +L  +A  + +  + A+   E R+      R+S    +P    K+   R   S 
Sbjct: 1693 SS---PELTRKARLSRRSRS-ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748

Query: 116  AAGYFRVWK------VPKPR---RKPGRARQEEG--TRAPWRTPAAPRSSRRRRQPLRKA 164
            ++   +          PKPR   R   R+R+E+   TR   R+ ++  +SRRR++   ++
Sbjct: 1749 SSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRS 1808

Query: 165  --ARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVK 222
               R+ R     ++R+ A+  +    +RR R R++ PP +R +  +  + A   R ++  
Sbjct: 1809 RVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRA 1868

Query: 223  EDTTPRSGKDK-----RRSSKPREEKQEPKKPAQRT 253
               T R  + +     RR S+ R      ++   RT
Sbjct: 1869 SPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRT 1904



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 63/260 (24%), Positives = 104/260 (40%), Gaps = 36/260 (13%)

Query: 8   EAQSRWPRRGGSGAMAEAPGPSGESR-GHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQ 66
           ++  + P+   S +   +P P+  SR   S+ + P      G  R  SSS          
Sbjct: 407 KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSS---------- 456

Query: 67  AISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRV---- 122
              T K  +    K++ ++  +   R+ GR  +P   AK    R       G+ R     
Sbjct: 457 --PTSKNRSHGRAKRD-KSHSHTPSRRMGRSRSP-ATAKRGRSRSRTPTKRGHSRSRSPQ 512

Query: 123 WKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKA 182
           W+  +  ++ GR+R  +  R   R+P  P  SR R    R  +R AR   R ++R+ A  
Sbjct: 513 WRRSRSAQRWGRSRSPQ-RRGRSRSPQRPGWSRSRNTQRRGRSRSARR-GRSHSRSPATR 570

Query: 183 NARARRT--RRARPRAKEPPCARAKEEA-------GATAADEGRGQAVKEDTTPRSGKDK 233
                RT  RR R R++ P   R++            T A  GR ++     TP   + +
Sbjct: 571 GRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRS----RTPARRRSR 626

Query: 234 RRSSKPREEKQEPKKPAQRT 253
            RS  P   +   + PA+R+
Sbjct: 627 TRS--PVRRRSRSRSPARRS 644



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 46/187 (24%), Positives = 69/187 (36%), Gaps = 36/187 (19%)

Query: 91   RRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAA 150
            RR+ GR   P    K +  R S +        WK  + R  P   R+        RTP  
Sbjct: 1836 RRRRGRSRTPPTSRKRSRSRTSPAP-------WKRSRSRASPATHRRSRS-----RTPLI 1883

Query: 151  P-RSSRRRRQPL-RKAARKAREVWRRNARAKAKANARARR-----------------TRR 191
              R SR R  P+ R+ +R    V RR +R++A   +R R                  T R
Sbjct: 1884 SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTR 1943

Query: 192  ARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDK-----RRSSKPREEKQEP 246
             R R++ PP  R +  +        R ++     T R  + +     RR S+ R      
Sbjct: 1944 RRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTR 2003

Query: 247  KKPAQRT 253
            ++   RT
Sbjct: 2004 RRSRSRT 2010



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 37/171 (21%), Positives = 67/171 (39%), Gaps = 32/171 (18%)

Query: 91  RRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAA 150
           R +  +  AP      +L+R S S  +        P P++K  + +++ G R+   +P  
Sbjct: 156 RAREAKQPAPEPPKPYSLVRESSSSRS--------PTPKQKKKKKKKDRGRRSESSSPRR 207

Query: 151 PRSS---------------RRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPR 195
            R                 R+ R P  K+ RK+++  R+ +R+   A  ++RR  R+   
Sbjct: 208 ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA-PKSRRAHRS--- 263

Query: 196 AKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEP 246
                 +     +  T+    R  A K  TT  +G+    +S  R E   P
Sbjct: 264 -----TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAP 309



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 56/251 (22%), Positives = 92/251 (36%), Gaps = 34/251 (13%)

Query: 15   RRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHKGL 74
            RRGGSG  + +P     SR  S  +    +T   P      S  R S             
Sbjct: 1814 RRGGSGYHSRSPARQESSRTSSRRRRGRSRT---PPTSRKRSRSRTSP------------ 1858

Query: 75   TLAALKKELRNAGYEVRRKSGRHEAP---RGQAKATLLRVSGSDAAGYFRVWKVPKPRRK 131
              A  K+    A     R+S R   P   R ++++    VS   +     V +    RR 
Sbjct: 1859 --APWKRSRSRASPATHRRS-RSRTPLISRRRSRSRTSPVSRRRSRSRTSVTR----RRS 1911

Query: 132  PGRARQEEGTRAPWRTPAAPRSSRRRRQPL--RKAARKAREVWRRNARAKA------KAN 183
              RA      R+  RTP   R   R R P   R++  +   V RR +R++       ++ 
Sbjct: 1912 RSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSR 1971

Query: 184  ARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSS-KPREE 242
            +R     R R R++  P  R +  +  +     R ++     T R  + +   + + R  
Sbjct: 1972 SRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSR 2031

Query: 243  KQEPKKPAQRT 253
             + P  P +R+
Sbjct: 2032 SRTPLLPRKRS 2042



 Score = 36.6 bits (83), Expect = 0.022
 Identities = 60/290 (20%), Positives = 101/290 (34%), Gaps = 52/290 (17%)

Query: 4   ALTGEAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQL 63
           A  G + SR P   G  + +  P   G SR  +  +  +        R  S +  R  + 
Sbjct: 557 ARRGRSHSRSPATRGR-SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRS 615

Query: 64  VLQAISTHKGLTLAALKKELRNAGYEVR--RKSGRHEAPRGQAKATLLRVSGSDAAGYFR 121
             +  +  +  T + +++  R+     R  R   R  A RG++++      G   +    
Sbjct: 616 RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR--- 672

Query: 122 VWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARA--- 178
                 P R+ GR+R     R        PR  R R + L +  R      +R  R+   
Sbjct: 673 -----TPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS 727

Query: 179 ---KAKANARARRTR---------------RAR----PRAK-------------EPPCAR 203
              K K+    RR+R               R+R    PR+K               PC +
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787

Query: 204 AKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQRT 253
            K +     +  G  Q   +  TP     + RSS     KQ+ K P++++
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTP---PRRSRSSSSPPPKQKSKTPSRQS 834



 Score = 36.6 bits (83), Expect = 0.022
 Identities = 50/230 (21%), Positives = 93/230 (40%), Gaps = 19/230 (8%)

Query: 9   AQSRWPRRGGSGAMAEAPGPSGESR-------GHSATQLPAEKTVGGPSRGCSSSVLRVS 61
           ++SR P R    + +  P   G SR       G S ++ PA ++    SR  +      S
Sbjct: 635 SRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRS 694

Query: 62  QLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFR 121
           +   +  S  + L    +++   ++    RR      + R     T  R S S+++    
Sbjct: 695 RTPRRGRSRSRSL----VRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP--- 747

Query: 122 VWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAK 181
             ++ K R    R+R     R+  ++  + R S     P  K  +K++   RR+    ++
Sbjct: 748 --EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK--QKSQTPPRRSRSGSSQ 803

Query: 182 ANARARRT-RRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSG 230
             A++R   RR+R  +  PP  ++K  +  + +       VK  T PR G
Sbjct: 804 PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG 853



 Score = 35.8 bits (81), Expect = 0.037
 Identities = 53/259 (20%), Positives = 91/259 (35%), Gaps = 47/259 (18%)

Query: 8    EAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQA 67
            E +SR P R        +P P+ +SR     +  +       SR   S   +   L    
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774

Query: 68   ISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPK 127
              + +  T    +++   +     R   R +  R +++ T  R  GS   GY        
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSR---RRQRSRSRSRVTRRRRGGS---GYH------- 1821

Query: 128  PRRKPGRARQEEGTRAPWRTPAAPRSSRRRR--------QPLRKAARKAREVWRRNARAK 179
                         +R+P R  ++  SSRRRR           R  +R +   W+R+    
Sbjct: 1822 -------------SRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRA 1868

Query: 180  AKANARARRTR-----RARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKR 234
            + A  R  R+R     R R R++  P +R +  +        R    +  +  R+    R
Sbjct: 1869 SPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS--------RTSVTRRRSRSRASPVSR 1920

Query: 235  RSSKPREEKQEPKKPAQRT 253
            R S+ R      ++   RT
Sbjct: 1921 RRSRSRTPPVTRRRSRSRT 1939



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 8/87 (9%)

Query: 129  RRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPL--RKAAR-KAREVWRRNARAKAKANAR 185
            RR   R       R+  RTP A R   R R PL  RK +R ++    RR +R++    AR
Sbjct: 2004 RRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTAR 2063

Query: 186  ARRTRRARPRAKEPPCARAKEEAGATA 212
             +R+       + PP  R +  +G+++
Sbjct: 2064 GKRS-----LTRSPPAIRRRSASGSSS 2085



 Score = 33.1 bits (74), Expect = 0.24
 Identities = 60/264 (22%), Positives = 98/264 (37%), Gaps = 33/264 (12%)

Query: 11   SRWPRRGGSGAMAEAPG-PSGESRGHSATQLPAEKTVGG-PSRGCSSSVLRVSQLVLQAI 68
            SR  R G S  + +  G PS  S   S+   P  K +   PSRG S          L   
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSS---PGMKDIPRTPSRGRSECDSSPEPKALP-- 1490

Query: 69   STHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKP 128
             T +  + +    EL N     +R+    E+   Q       +     +G  +   V KP
Sbjct: 1491 QTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV-KP 1549

Query: 129  RRKPGRARQEEGT---RAPWRTPAAPRS---------SRRRRQPLRKAARKAREVWRRNA 176
               P    + + +   +A  RTP   RS         S+ R  P R  +  + EV     
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV----- 1604

Query: 177  RAKAKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTT--------PR 228
            + K +A  RA+    + P  K P        + + ++ +GRG + +  ++        P+
Sbjct: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664

Query: 229  SGKDKRRSSKPREEKQEPKKPAQR 252
            S   +R S    E K + + P +R
Sbjct: 1665 SRTARRGSRSSPEPKTKSRTPPRR 1688



 Score = 28.1 bits (61), Expect = 7.8
 Identities = 27/126 (21%), Positives = 51/126 (40%), Gaps = 21/126 (16%)

Query: 128 PRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARAR 187
           P+R+   A+Q      P   P  P S  R     R    K ++        K K   R R
Sbjct: 153 PQRRAREAKQ------PAPEPPKPYSLVRESSSSRSPTPKQKK--------KKKKKDRGR 198

Query: 188 RTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPK 247
           R+  + PR +    ++ K+    + + + + ++     TP+S   KR+S   + ++    
Sbjct: 199 RSESSSPRRERKKSSKKKKHRSESESKKRKHRS----PTPKS---KRKSKDKKRKRSRST 251

Query: 248 KPAQRT 253
            PA ++
Sbjct: 252 TPAPKS 257


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 61/256 (23%), Positives = 106/256 (41%), Gaps = 33/256 (12%)

Query: 17  GGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHK---- 72
           GGS   A A   +  + G +  + PA    GGP+ G ++S  R S     + S  +    
Sbjct: 333 GGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSS 392

Query: 73  GLTLAALKKELRNAGYEVRRKSGRHEAPR--------------GQAKATLLRVSGSDAAG 118
             +  +  +  R  GY    +SGRH   R               ++++   R SG  +  
Sbjct: 393 RSSSRSSSRSRRGGGY---YRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRD 449

Query: 119 YFRVWKVPKPR-----RKPGRARQEEGTR-APWRTPAAPRSSRRRRQPLRKAARKAREVW 172
             R  + P  R     R+  R+R   G R           SS R R     +  ++R + 
Sbjct: 450 GHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLT 509

Query: 173 RRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKD 232
           R  + + + + +R+    R+R R++ P  + A+E+    AA    G+ +K+ T P +GK+
Sbjct: 510 RSRSHSPSPSQSRS----RSRSRSQSPSPSPAREKLTRPAASPAVGEKLKK-TEPAAGKE 564

Query: 233 KRRSSKPREEKQEPKK 248
              ++KP+   QE  K
Sbjct: 565 -TGAAKPKLTPQEKLK 579


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 40/139 (28%), Positives = 64/139 (46%), Gaps = 22/139 (15%)

Query: 129 RRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNA--RAKAKANARA 186
           +R+  R+R     R   RTP++ R  R R +  R++  K+R   R  +  R ++ +  R 
Sbjct: 245 KRRHSRSRSRSRRR---RTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERG 301

Query: 187 RRTR------------RARPRAKEPPCARAKEEAGATAADEGRGQAVKEDT----TPRSG 230
           RR+R            + + R+K PP + +      +A+ E R +  +  T     PRS 
Sbjct: 302 RRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSP 361

Query: 231 KDK-RRSSKPREEKQEPKK 248
           K K  RS  PR  K+E KK
Sbjct: 362 KRKLSRSPSPRRHKKEKKK 380



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 12/106 (11%)

Query: 154 SRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAA 213
           SRRRR P     R++R   RR + +K+++  R++  RR R  ++E    R       T  
Sbjct: 255 SRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER--GRRSRSTSKTRD 312

Query: 214 DEGRGQAVKEDTTP----------RSGKDKRRSSKPREEKQEPKKP 249
            +   +  K   TP          RS   +RR  + R   + PKKP
Sbjct: 313 KKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKP 358



 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 37/161 (22%), Positives = 60/161 (37%), Gaps = 6/161 (3%)

Query: 91  RRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAA 150
           RR+S   E  R     +  R    +     R    PK      R+R     R   R+ + 
Sbjct: 292 RRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSG 351

Query: 151 PRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGA 210
            RS ++ R P RK +R       +  + K K   R+R  R      K+    + K+    
Sbjct: 352 TRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERK 411

Query: 211 TAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQ 251
           + +D+   Q  ++      G D  +      EK+E KKP +
Sbjct: 412 SESDKDVKQVTRDYDEEEQGYDSEK------EKKEEKKPIE 446



 Score = 36.2 bits (82), Expect = 0.029
 Identities = 42/162 (25%), Positives = 69/162 (42%), Gaps = 15/162 (9%)

Query: 91  RRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAA 150
           RR+S      R ++K+   R S S   G  R     K R K    ++E+  +   +TP  
Sbjct: 274 RRRSHSKSRSRRRSKSPRRRRSHSRERGR-RSRSTSKTRDK----KKEDKEKKRSKTPPK 328

Query: 151 PRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGA 210
             S+ RR    R A+R+ R   RR +R+  ++  + R  +R   R+  P     KE+   
Sbjct: 329 SYSTARRS---RSASRERR---RRRSRSGTRSPKKPRSPKRKLSRSPSPR-RHKKEKKKD 381

Query: 211 TAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQR 252
              +  R +  +  +  +  KDK    K RE K E  K  ++
Sbjct: 382 KDKERSRDERERSTSKKKKSKDK---EKDRERKSESDKDVKQ 420



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 22/100 (22%), Positives = 44/100 (44%), Gaps = 6/100 (6%)

Query: 156 RRRQPLRKAARKAREVWRRNARAKAKANARARRT------RRARPRAKEPPCARAKEEAG 209
           R  Q L  AA +  +   +   +++++ +R RRT      RR+R R++    ++++    
Sbjct: 227 REAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRR 286

Query: 210 ATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKP 249
           + +    R  + +     RS    R   K  +EK+  K P
Sbjct: 287 SKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTP 326


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 45/193 (23%), Positives = 79/193 (40%), Gaps = 27/193 (13%)

Query: 84  RNAGYEVRRK--SGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQ---- 137
           R  G ++RRK  + R E  R ++ +     + + AAG     K  + R++ G A++    
Sbjct: 476 RWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASS 535

Query: 138 EEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKA--------------- 182
             GT+     PA+P  S++ R   RK    A    RR +R+++++               
Sbjct: 536 SSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRG 595

Query: 183 ---NARARRTRRARPRAKEPPCARAKEEAGATAADEGR---GQAVKEDTTPRSGKDKRRS 236
               +R+R  RR R R+  PP A +   +       G+   G   K+       + ++RS
Sbjct: 596 GSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRS 655

Query: 237 SKPREEKQEPKKP 249
               E+   P  P
Sbjct: 656 GDGSEKAPAPAPP 668



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 44/181 (24%), Positives = 72/181 (39%), Gaps = 31/181 (17%)

Query: 80  KKELRNAGYEVRRKS---GRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRAR 136
           +K   +A    RR+S    R  + R ++++T  R  GS              RR   R +
Sbjct: 560 RKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGS--------------RRSRSREK 605

Query: 137 QEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRA 196
           +    R+    PA   SS  RR+  R   R            K K  +R+R  +R+   +
Sbjct: 606 RRRRRRSASPPPATSSSSSSRRERHRGKHRDG------GGSKKKKKRSRSRGEKRSGDGS 659

Query: 197 KEPPCARAKEEAGATAA---DEGRGQAVKEDTTPRSGKD----KRRSSKPREEKQEPKKP 249
           ++ P A A   +G+T+    D  R  AV       +  D    KR  +  R +K +P+ P
Sbjct: 660 EKAP-APAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGP 718

Query: 250 A 250
           +
Sbjct: 719 S 719


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 6/135 (4%)

Query: 124 KVPKPRRKPGRARQEE---GTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKA 180
           K  K R+K  R ++ E     R   R     +  R+R++  +K  RK R    R  + + 
Sbjct: 61  KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120

Query: 181 KANARARRTRRARPRAKEPPCARAKE---EAGATAADEGRGQAVKEDTTPRSGKDKRRSS 237
           K   R  + RR R R K     R KE   E      +  R +  KE+   +  ++++   
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180

Query: 238 KPREEKQEPKKPAQR 252
           K RE K+  ++  +R
Sbjct: 181 KERERKERRERKKER 195



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 44/177 (24%), Positives = 69/177 (38%), Gaps = 14/177 (7%)

Query: 80  KKELRNAGYEVRRKSGRHEAPRG--QAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQ 137
           KKE R      R +    +  RG  + K    R  G +        +  K R K  + R+
Sbjct: 37  KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERE------RKRKEREKQRKERR 90

Query: 138 EEGTRAPWRTPAA-PRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRA 196
           E+  R   +      R  R RR+  +K  RK RE   +  R + +   R ++ R+ R R 
Sbjct: 91  EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150

Query: 197 KEP-----PCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKK 248
           KE         + K+E      +  R +  KE       + K+   K R +K+E KK
Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 22/112 (19%), Positives = 47/112 (41%)

Query: 137 QEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRA 196
           Q E  R   R     R   R ++  R+  +K ++  ++  R K +   R  R ++ + R 
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90

Query: 197 KEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKK 248
           ++    R KE+        GR +  K+       ++ ++  + + +K+  KK
Sbjct: 91  EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 33/136 (24%), Positives = 56/136 (41%), Gaps = 20/136 (14%)

Query: 124 KVPKPRRKPGRARQEEGTRAPWRTPAAPRSSR-------RRRQPLRKAARKAREVWRRNA 176
           K  + R K  R R++E  R   +     R  R       R+R+   K  ++ RE  RR  
Sbjct: 38  KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKR 97

Query: 177 RAKAKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRS 236
           + + K   R +R RR R + KE    R + E         R    + +   +  + K+R 
Sbjct: 98  KKEKKKRERKQRGRRERKKKKE----RKERE---------RENKQRRERKRKKRRKKKRR 144

Query: 237 SKPREEKQEPKKPAQR 252
            + + EK+  K+  +R
Sbjct: 145 KERKREKERGKRERKR 160



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 12/133 (9%)

Query: 129 RRKPGRARQEEGTRAPWRTPAAPRSSR---------RRRQPLRKAARKAREVWRRNARAK 179
           R +  R R+ E  R   R     +  +         R+R+   K  ++ RE  RR  + +
Sbjct: 41  REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE 100

Query: 180 AKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKP 239
            K   R +R RR R + KE    + +E       +  R +  K+       ++K R  + 
Sbjct: 101 KKKRERKQRGRRERKKKKE---RKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157

Query: 240 REEKQEPKKPAQR 252
           R+ K+  K+  ++
Sbjct: 158 RKRKKRKKEEREK 170



 Score = 35.0 bits (79), Expect = 0.063
 Identities = 20/69 (28%), Positives = 30/69 (43%)

Query: 127 KPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARA 186
           K RRK  +  +E G R   R         ++R+  RK  +K RE   R  R K +   R 
Sbjct: 141 KKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERR 200

Query: 187 RRTRRARPR 195
           ++  R + R
Sbjct: 201 KKKERKKDR 209



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 169 REVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPR 228
           RE  R+  R + +   R R   R R R K+    R K E G    +  R +  +E     
Sbjct: 32  RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGK---ERERKRKEREKQRKE 88

Query: 229 SGKDKRRSSKPREEKQEPKKPAQR 252
             + +RR  K  ++K+E K+  +R
Sbjct: 89  RREKERRKRKKEKKKRERKQRGRR 112


>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 48/224 (21%), Positives = 91/224 (40%), Gaps = 32/224 (14%)

Query: 35  HSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHKGLTLAALKKELRNAGYEVRRKS 94
           H   +       G  S G SSS  R S       S+    +  + +   R++  + +++ 
Sbjct: 499 HKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRH 558

Query: 95  GRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSS 154
            R  +P  +A+ +  R        Y R  K+     +  RAR +   R      +  R  
Sbjct: 559 SRSRSPTIKARRSRSR-------SYSRRIKI-----ESNRARVKIRDRRRSNRNSIERER 606

Query: 155 RRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAAD 214
           RR R P R+             R ++++ +R RRT RA  R++     +  ++ G  + +
Sbjct: 607 RRNRSPSRE-------------RRRSRSRSRDRRTNRA-SRSRSRDRRKIDDQRGNLSGN 652

Query: 215 ------EGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQR 252
                 E + Q  K++ +    KD+++  K RE +Q+ +K  Q+
Sbjct: 653 SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696


>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 48/224 (21%), Positives = 91/224 (40%), Gaps = 32/224 (14%)

Query: 35  HSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQAISTHKGLTLAALKKELRNAGYEVRRKS 94
           H   +       G  S G SSS  R S       S+    +  + +   R++  + +++ 
Sbjct: 499 HKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRH 558

Query: 95  GRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSS 154
            R  +P  +A+ +  R        Y R  K+     +  RAR +   R      +  R  
Sbjct: 559 SRSRSPTIKARRSRSR-------SYSRRIKI-----ESNRARVKIRDRRRSNRNSIERER 606

Query: 155 RRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAAD 214
           RR R P R+             R ++++ +R RRT RA  R++     +  ++ G  + +
Sbjct: 607 RRNRSPSRE-------------RRRSRSRSRDRRTNRA-SRSRSRDRRKIDDQRGNLSGN 652

Query: 215 ------EGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQR 252
                 E + Q  K++ +    KD+++  K RE +Q+ +K  Q+
Sbjct: 653 SHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 1/118 (0%)

Query: 130 RKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRT 189
           R+  R ++ +  R   R     R   R R   ++  R+  E  R   R + +   R R  
Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERER 774

Query: 190 RRARPRAKEPPCARAKEEAGATAADEG-RGQAVKEDTTPRSGKDKRRSSKPREEKQEP 246
            RAR R KE    R  E+      D   + + ++ED  PR G D+R+S K    +  P
Sbjct: 775 ERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSP 832



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 8/130 (6%)

Query: 129 RRKPGRARQEEGTRAPWRTPAAP-----RSSRRRRQPLRKAARKAREVWRRNARAKAKAN 183
           RR   R R++   R   + P++P     R+    R   R+  R  R   RR+ RA+ +  
Sbjct: 624 RRHGERDRRDNRERD--QRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDR 681

Query: 184 ARARRTRRARPRAKEPPCARAKE-EAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREE 242
            R R   R R R +E    R KE E     A E   +  KE    R         + RE 
Sbjct: 682 ERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERER 741

Query: 243 KQEPKKPAQR 252
           +++ +K  +R
Sbjct: 742 ERDREKERER 751



 Score = 33.1 bits (74), Expect = 0.24
 Identities = 21/99 (21%), Positives = 44/99 (44%), Gaps = 2/99 (2%)

Query: 153 SSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATA 212
           S RR+R P     R      RR+A      +  + + +++ PR + P   + + +   T+
Sbjct: 348 SPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTS 407

Query: 213 ADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQ 251
               R    +EDT  R  +D+ + S+   E ++ +  ++
Sbjct: 408 QSHDRRHERREDT--RGKRDREKDSREEREYEQDQSSSR 444



 Score = 32.0 bits (71), Expect = 0.54
 Identities = 40/167 (23%), Positives = 62/167 (37%), Gaps = 14/167 (8%)

Query: 92  RKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAAP 151
           R+ GRH+  R             D  G        K  R+     Q++ +    R    P
Sbjct: 396 REKGRHDHERTSQSHDRRHERREDTRGKR---DREKDSREEREYEQDQSSSRDHRDDREP 452

Query: 152 RSSRRRRQPLRKAARKAREVW-RRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGA 210
           R  R RR    +  R  RE+   R+ R   +    +R T+ +R    +P  +R+  +A  
Sbjct: 453 RDGRDRRDA--RDTRDRRELRDSRDMRDSREMRDYSRDTKESR----DPRDSRSTRDAHD 506

Query: 211 TAADEGRGQAVKEDTTPRS----GKDKRRSSKPREEKQEPKKPAQRT 253
               EGR    KEDT P      G++  R    R E +   +   R+
Sbjct: 507 YRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRS 553



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 21/101 (20%), Positives = 40/101 (39%)

Query: 152 RSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGAT 211
           R  RR  +   +   +ARE  R   R + +   R R   R R + +E    RA+E     
Sbjct: 660 REERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERER 719

Query: 212 AADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQR 252
             +  R +    D      +++ R  +   E++  ++  +R
Sbjct: 720 EKERDRERDRDRDHDRERERERERDREKEREREREERERER 760


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 16/143 (11%)

Query: 125 VPKPRRKPG-------RARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNAR 177
           + KP  +PG       R R+ E  +   +   + R   RR +  RK  R+      R  +
Sbjct: 25  ISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKK 84

Query: 178 AKAKANARARRTRRARPRAKEPPCARAKE--------EAGATAADEGRGQAVKEDTTPRS 229
            K     +  R R+ R R KE      KE        E G T+  EG+ +  KE+     
Sbjct: 85  EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSK-EGKERERKEERKREE 143

Query: 230 GKDKRRSSKPREEKQEPKKPAQR 252
            K++ R  + RE+++E K+  +R
Sbjct: 144 RKERERKKEEREKERERKERKKR 166



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 8/123 (6%)

Query: 129 RRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARR 188
           R K  +  +E+  R         R+S+  ++  RK  RK  E   R  + + +   R R+
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161

Query: 189 TRRARPR---AKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQE 245
            R+ R R    ++    + KE       +  R +  KE    R  K++R   K R+ K+E
Sbjct: 162 ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE----RERKERRERKKERK-KKE 216

Query: 246 PKK 248
            +K
Sbjct: 217 ERK 219



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 8/130 (6%)

Query: 127 KPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKA----KA 182
           K + K  R R  +  +   R     R  R+ R+  ++   K RE   R  R +     K 
Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKE 175

Query: 183 NARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPRE- 241
             R  + R+ R + +     R KE       +  + +  KE+      KD++ + + +E 
Sbjct: 176 EERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235

Query: 242 ---EKQEPKK 248
              E++E KK
Sbjct: 236 GKRERKERKK 245


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 63/254 (24%), Positives = 94/254 (37%), Gaps = 36/254 (14%)

Query: 14   PRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSS-----VLRVSQLVLQAI 68
            P +  +G   E+  P          Q P     G P+RG   +         +    Q  
Sbjct: 884  PLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGR 943

Query: 69   STHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKP 128
               +G  L   +K+L + G      SG      G  +A+ LR   +D  G     +  +P
Sbjct: 944  QQRRGKQLKLFRKDLDSGGAAEGSGSG------GGGRASGLRPRRNDGLGERPPPRPRRP 997

Query: 129  RRKPGRARQEEGTRAPWRTPAAP---RSSRRRRQPLRKAARKAREVWRRNARAKAKANAR 185
            R +   +R +   R P R  A P   RSSRRRR P RK  RK      R AR  A     
Sbjct: 998  RTQAPGSRADPAPRVP-RAAALPEETRSSRRRRLPPRKDPRK------RKARGGAWGKEL 1050

Query: 186  ARRTRRARPRAKEPPCARAKEE-------AGATAADEGRGQAVKEDTTPRSGKDKRRSSK 238
              +  + + R +E   A   EE               GRG+  KE    +  ++      
Sbjct: 1051 ILKIVQQKNRLREYDFASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPRE------ 1104

Query: 239  PREEKQEPKKPAQR 252
              +E Q+P+K A++
Sbjct: 1105 --DEPQKPRKAARQ 1116


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 39/185 (21%), Positives = 82/185 (44%), Gaps = 26/185 (14%)

Query: 80  KKELRNAGYEVRRKSGRHEAPRGQAKA---TLLRVSGSDAAGYFRVWKVPKPR-RKPGRA 135
           KKE   +  + + +S  H A + ++K+      ++  +D  G        KP+ R P R 
Sbjct: 243 KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVG--------KPKSRSPSRH 294

Query: 136 RQEEGTRA---PWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRA 192
           + +  +R+     R     R S  R +   K+ R++R      +R+++K  +R+R   R+
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSR------SRSRSKGGSRSRSRSRS 348

Query: 193 RPRAKEPPCARAKEEA-----GATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPK 247
           + + K     R++EE+       + ++  R +  K D+   S K K++    R + + P 
Sbjct: 349 KSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS 408

Query: 248 KPAQR 252
           +   +
Sbjct: 409 RSVSK 413



 Score = 35.8 bits (81), Expect = 0.037
 Identities = 48/231 (20%), Positives = 92/231 (39%), Gaps = 21/231 (9%)

Query: 7   GEAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSV-LRVSQLVL 65
           G+ +SR P R  S           +SR  S  +   E+  G  SRG S    LR S+   
Sbjct: 284 GKPKSRSPSRHKS---------KSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRS 334

Query: 66  QAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKV 125
           ++    +  + +  K + +  G +  R+  R  + R ++K+   R  GS      R  K 
Sbjct: 335 RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRS-RSRSKSERSRKRGSK-----RDSKA 388

Query: 126 PKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANAR 185
              ++K    ++E+  R+  R+P+   S  R       + R+ R     NA    +  +R
Sbjct: 389 GSSKKK----KKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE-SENAGTNQETRSR 443

Query: 186 ARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRS 236
           +R   +++P       +R+K  +   +  + R ++     +    +   RS
Sbjct: 444 SRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494



 Score = 29.3 bits (64), Expect = 3.5
 Identities = 58/257 (22%), Positives = 94/257 (36%), Gaps = 31/257 (12%)

Query: 11  SRWPRRGGS---GAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCS----SSVLRVSQL 63
           +R PRR GS   G        SG  +    T+      V   S  CS       +R +  
Sbjct: 70  ARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGE 129

Query: 64  VLQAISTHKG---------LTLAALKKELRNA-GYEVR-RKSGRHEAPRGQAKATLLRVS 112
           V  A   HKG         ++ + +K+ L    G EV  RK    E   G  +      S
Sbjct: 130 VTYA-DAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRS 188

Query: 113 GSDAAGYFRVWKVPKPRRKPGRARQEEG-TRAPWRTPAAPRSSRRRRQPLRKAARKAREV 171
            S +    R     K R + G ++     +R+  R+ +  RS  R R   R  ++K +  
Sbjct: 189 RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEK-- 246

Query: 172 WRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGK 231
               +R+ +K  +R+R     + R+K    A  K +      ++  G+      +    K
Sbjct: 247 ----SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQ-----NNDNVGKPKSRSPSRHKSK 297

Query: 232 DKRRSSKPREEKQEPKK 248
            K RS       +E K+
Sbjct: 298 SKSRSRSQERRVEEEKR 314


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 11/129 (8%)

Query: 130 RKPGRARQEEGTRAPWRTPAAPRSSR---RRRQPLRKAARKAREVWRRNARAKAKANARA 186
           RK   +R   G+R+  R+P+  RS R   RR +   +  R+ R   R   R++++   R 
Sbjct: 9   RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRL 68

Query: 187 RRTR-RARPRAKEPPCARAKEEAGATAADEGR-------GQAVKEDTTPRSGKDKRRSSK 238
           RR+R R R R++E   +R+++   + +   GR       G   K+       K+K    +
Sbjct: 69  RRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGE 128

Query: 239 PREEKQEPK 247
             +EK++ K
Sbjct: 129 SSKEKKKDK 137



 Score = 36.2 bits (82), Expect = 0.029
 Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)

Query: 129 RRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARR 188
           RR   R R     R+  R     RS  R+R    ++  + R   RR +R++ +  +R+ R
Sbjct: 38  RRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRS-R 96

Query: 189 TRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQE 245
           +R  R R+  P           +   E R ++ ++     S K+K++    +E+++E
Sbjct: 97  SRGRRSRSSSP--------GNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKE 145


>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
          Length = 334

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 44/165 (26%), Positives = 70/165 (42%), Gaps = 21/165 (12%)

Query: 91  RRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAA 150
           RR S   E  R + K    R S S ++   R +      RK G  +    +R+ W     
Sbjct: 3   RRSSDTEEESRSKRKKKHRRRSSSSSSSDSRTYS-----RKKGGRKSRSKSRS-WSRDLQ 56

Query: 151 PRS---SRRRRQPLRKAA----RKAREVWRRNARAKAKANARAR---RTRRARPRAKEPP 200
           PRS    RRRR     ++    R+ R   R   R K+    R+R   RTRR+R R +   
Sbjct: 57  PRSHSYDRRRRHRSSSSSSYGSRRKRSRSRSRGRGKSYRVQRSRSKSRTRRSRSRPRLRS 116

Query: 201 CARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQE 245
            +R+ E +        R ++   D   R G+DK +  K +++ ++
Sbjct: 117 HSRSSERSS-----HRRTRSRSRDRERRKGRDKEKREKEKDKGKD 156


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 18/162 (11%)

Query: 90  VRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPA 149
           VR   GR +AP           SGS  +G  +     +P    G   ++ G   P +   
Sbjct: 623 VRSSGGRMDAP----------ASGSACSGLNK----QEPGGSHGSETEDTGRSLPSKKER 668

Query: 150 APRSSRRRRQPLRKAARKAREVWRRNAR---AKAKANARARRTRRARPRAKEPPCARAKE 206
           + +S R +++   K + K +   + +     +KA++  ++++ R+ R R K    A A  
Sbjct: 669 SGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKK-RKKRKRKKNKSSAPADS 727

Query: 207 EAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKK 248
           E G      G G         R+  D +R S P EE    KK
Sbjct: 728 ERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKK 769


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 31/131 (23%), Positives = 53/131 (40%), Gaps = 10/131 (7%)

Query: 124 KVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKAN 183
           K P P +   + +++E TR   R+ +  RS  R R P     R+      R+   + + +
Sbjct: 257 KEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS 316

Query: 184 ARARRT--RRARPRAKEPP--------CARAKEEAGATAADEGRGQAVKEDTTPRSGKDK 233
            R R +  RR  PR   PP          R +  + A+ +      +     +P     K
Sbjct: 317 PRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPK 376

Query: 234 RRSSKPREEKQ 244
           R SS PR+ ++
Sbjct: 377 RTSSPPRKTRR 387



 Score = 36.2 bits (82), Expect = 0.029
 Identities = 26/130 (20%), Positives = 56/130 (43%), Gaps = 2/130 (1%)

Query: 124 KVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKAN 183
           K  K  ++  R ++E  +R+P R  +   S RRR  P+R+  +++     R+ R K+++ 
Sbjct: 153 KRDKEEKESSREKRER-SRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRH-RTKSRSP 210

Query: 184 ARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEK 243
           + A   +   P   EP     +       +     +  K +  P   +     +  +E++
Sbjct: 211 SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKE 270

Query: 244 QEPKKPAQRT 253
           +E  +P  R+
Sbjct: 271 KEKTRPRSRS 280



 Score = 28.5 bits (62), Expect = 5.9
 Identities = 30/125 (24%), Positives = 48/125 (38%), Gaps = 15/125 (12%)

Query: 126 PKPRRKPGRARQEEGTRAPWRTPAAPRSS--RRRRQPLRKAARKAREVWRRNARAKAKAN 183
           PK R  P    +   + +P   P   RSS   +RR P   +  +      R+ R      
Sbjct: 621 PKRRASPSPPPKRRVSHSP---PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677

Query: 184 ARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEK 243
              R +   RPRA +   +      GA+++ + R     +  +P +   +R S  P    
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRR-----QSPSPSTRPIRRVSRTP---- 728

Query: 244 QEPKK 248
            EPKK
Sbjct: 729 -EPKK 732


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 19/163 (11%)

Query: 91  RRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAA 150
           RR+ G  E+PR +     L  +  DA G  R            R RQ+E  R   +    
Sbjct: 28  RRRPGSQESPRRRG----LGQAHKDADGDDRE-----------RNRQKERERRREKRQTE 72

Query: 151 PRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEAGA 210
             + R+R +   K   + R+  R   R + +   R R+T R R R +E    R KE    
Sbjct: 73  RETDRKRERRREKDRHRKRD--RHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130

Query: 211 TAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQRT 253
           T  +  RG+     T  +  ++++R ++   E+Q  ++  ++T
Sbjct: 131 TEREGERGR--DRQTDGQRERERQRDAEKERERQTDRERQRQT 171



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 1/124 (0%)

Query: 130 RKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAR-EVWRRNARAKAKANARARR 188
           R+  R R+ E  R   R     R + R R+  R+  RK + E+ R   R   +   R   
Sbjct: 309 RERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAE 368

Query: 189 TRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKK 248
             R R R ++   AR +EE       + + +  ++    R G+ +    + RE+ +E ++
Sbjct: 369 RERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428

Query: 249 PAQR 252
             +R
Sbjct: 429 GRER 432



 Score = 36.6 bits (83), Expect = 0.022
 Identities = 30/116 (25%), Positives = 48/116 (41%), Gaps = 14/116 (12%)

Query: 130 RKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARA--- 186
           R+  R    EG R       A R   R R+  R++AR+  E  R   R + K   R    
Sbjct: 353 RERNRQTGREGRRQ------AERERERERERDRQSAREREERERDRDRDRQKERERQTEK 406

Query: 187 -----RRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSS 237
                R T + R R K+    R +E        +GR +  +  T  ++G+ ++RS+
Sbjct: 407 DRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST 462



 Score = 31.6 bits (70), Expect = 0.70
 Identities = 31/123 (25%), Positives = 49/123 (39%), Gaps = 5/123 (4%)

Query: 130 RKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRT 189
           R   R R+ E  R         R + R R   RK  R+ RE      RA  +   R +  
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTERE-REKQAERERASERETERDKER 262

Query: 190 RRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKP 249
            R R R ++    R KE    T  D  R +  + D      ++++R  + RE ++  K+ 
Sbjct: 263 ERERDRDRDRD-RRQKERERQT--DRKRQRRTERDRETERKRERQR-ERERERERNRKRE 318

Query: 250 AQR 252
            +R
Sbjct: 319 RER 321


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 29/117 (24%), Positives = 54/117 (46%), Gaps = 9/117 (7%)

Query: 135 ARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARP 194
           A  E+  ++P +  A  +S    + P ++ A+   EV     ++  KA + A+   ++ P
Sbjct: 510 ASPEKEAKSPVKEEA--KSPAEAKSPEKEEAKSPAEV-----KSPEKAKSPAKEEAKSPP 562

Query: 195 RAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEPKKPAQ 251
            AK P    AK  A   + ++ +  A +E  +P   K   ++  P   K+E K PA+
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP--VKEEAKSPAE 617



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 30/138 (21%), Positives = 59/138 (42%), Gaps = 13/138 (9%)

Query: 124 KVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAAR---KAREVWRRNARAKA 180
           K P+  + P +A  +   +A     A  +S  + + P+++ A+   KA+   +  A++  
Sbjct: 661 KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE 720

Query: 181 KANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRS---- 236
           KA +  +   +   +AK P    AK    A + ++ +   VK        K++ RS    
Sbjct: 721 KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780

Query: 237 ------SKPREEKQEPKK 248
                 S  +EE + P+K
Sbjct: 781 FPEKAKSPVKEEVKSPEK 798



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 10/126 (7%)

Query: 124 KVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKAN 183
           K P+  + P +A+  +      +TPA        R P  K   KA+   +   ++  KA 
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEAKTPA----KEEARSPADKFPEKAKSPVKEEVKSPEKAK 800

Query: 184 ARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPR-EE 242
           +  +   +A P  + P     KEE  +   +E + Q VK    P+  ++++  + P+ EE
Sbjct: 801 SPLKEDAKA-PEKEIP----KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855

Query: 243 KQEPKK 248
           K++ KK
Sbjct: 856 KKDSKK 861



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 8/130 (6%)

Query: 125 VPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAAR---KAREVWRRNARAKAK 181
           V +  + P  A+      A  ++PA  +S  + + P ++ A+   KA+   +  A++  K
Sbjct: 608 VKEEAKSPAEAKSPVKEEA--KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665

Query: 182 ANARARRTRRARPRAKEPPCARAK--EEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKP 239
           A +  +   ++  +AK P  A AK  E+A +   +E +     +       K   ++  P
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725

Query: 240 -REEKQEPKK 248
            +EE + P+K
Sbjct: 726 VKEEAKTPEK 735



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 26/128 (20%), Positives = 56/128 (43%), Gaps = 4/128 (3%)

Query: 125 VPKPRRKPGRARQEEGTRAPWRTPA-APRSSRRRRQPLRKAARKAREVWRRNARAKAKAN 183
           V +  + P   +  E  ++P +  A +P  ++   +   K+  KA+   +  A++  KA 
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681

Query: 184 ARARRTRRARPRAKEPPCARAK--EEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKP-R 240
           +  +   ++  +AK P    AK  E+A +   +E +     +       K   ++  P +
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741

Query: 241 EEKQEPKK 248
           EE + P+K
Sbjct: 742 EEAKSPEK 749



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 51/259 (19%), Positives = 101/259 (38%), Gaps = 32/259 (12%)

Query: 8   EAQSRWPRRGGSGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRGCSSSVLRVSQLVLQA 67
           EA+    +    G   EA G      G   T+ P  +    P +   S V   ++   +A
Sbjct: 477 EAKEEEGKEEEGGEEEEAEG------GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEA 530

Query: 68  ISTHK--GLTLAALK--KELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVW 123
            S  K    + A +K  ++ ++   E  +     ++P  +   +   V   + A      
Sbjct: 531 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA------ 584

Query: 124 KVP--KPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAAR---------KAREVW 172
           K P  +  + P  A+  E  ++P +  A  +S    + P+++ A+         KA+   
Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEA--KSPAEAKSPVKEEAKSPAEVKSPEKAKSPT 642

Query: 173 RRNARAKAKANARARRTRRARPRAKEPPCARAK--EEAGATAADEGRGQAVKEDTTPRSG 230
           +  A++  KA +  +   ++  +AK P  A AK  E+A +    E +     +       
Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702

Query: 231 KDKRRSSKP-REEKQEPKK 248
           K   ++  P +EE + P+K
Sbjct: 703 KSPEKAKSPVKEEAKSPEK 721



 Score = 36.6 bits (83), Expect = 0.022
 Identities = 30/128 (23%), Positives = 62/128 (48%), Gaps = 8/128 (6%)

Query: 124 KVPKPRRKPGR--ARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAK 181
           K P+  + P +  A+  E  ++P +  A  +S  + + P+ KA  K+ E  +   +A+AK
Sbjct: 633 KSPEKAKSPTKEEAKSPEKAKSPEKEEA--KSPEKAKSPV-KAEAKSPEKAKSPVKAEAK 689

Query: 182 ANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDK-RRSSKPR 240
           +  +A+     +  AK P  A++  +  A + ++ +    +E  TP   K   +  +K  
Sbjct: 690 SPEKAKSP--VKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747

Query: 241 EEKQEPKK 248
           E+ + P+K
Sbjct: 748 EKAKSPEK 755



 Score = 35.4 bits (80), Expect = 0.049
 Identities = 26/133 (19%), Positives = 57/133 (42%), Gaps = 13/133 (9%)

Query: 130 RKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAAR---------KAREVWRRNARAKA 180
           + P  A+  E   A  ++PA  +S  + + P ++ A+         KA+   +  A++ A
Sbjct: 559 KSPPEAKSPEKEEA--KSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA 616

Query: 181 KANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKD--KRRSSK 238
           +A +  +   ++    K P  A++  +  A + ++ +    +E  +P   K   K  +  
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676

Query: 239 PREEKQEPKKPAQ 251
           P + K   K  A+
Sbjct: 677 PEKAKSPVKAEAK 689



 Score = 35.0 bits (79), Expect = 0.063
 Identities = 38/172 (22%), Positives = 67/172 (38%), Gaps = 28/172 (16%)

Query: 89   EVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTP 148
            E ++ S + EAP+ +A    +      A        V KP+     A++EE         
Sbjct: 854  EEKKDSKKEEAPKKEAPKPKVEEKKEPA--------VEKPKESKVEAKKEE--------- 896

Query: 149  AAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRARPRAKEPPCARAKEEA 208
                +  +++ P  +    A+   + +A+ K K     +    A+  AKEP     K+EA
Sbjct: 897  ----AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK--AKEPSKPAEKKEA 950

Query: 209  GATAADEGRGQAVKEDTTPRS-----GKDKRRSSKPREEKQEPKKPAQRTIQ 255
                 D    +A K +  P++       DK  S +P + K E  + +  T Q
Sbjct: 951  APEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQ 1002



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 28/126 (22%), Positives = 51/126 (40%), Gaps = 12/126 (9%)

Query: 127 KPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARA 186
           K +  P +A +E+    P       + S++   P ++A +   E  +  A  K K +   
Sbjct: 834 KVKEPPKKAEEEKAPATP--KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891

Query: 187 RRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPREEKQEP 246
            +   A  + K P     ++EA A          VKED  P+   +  +      + +EP
Sbjct: 892 AKKEEAEDKKKVPT---PEKEAPAKVE-------VKEDAKPKEKTEVAKKEPDDAKAKEP 941

Query: 247 KKPAQR 252
            KPA++
Sbjct: 942 SKPAEK 947


>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 753

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 42/131 (32%), Positives = 56/131 (42%), Gaps = 9/131 (6%)

Query: 124 KVPKPRRKPGRARQEEGTRAPWRTP---AAPRSSRRRRQPLRKAARKAREVWRRNARAKA 180
           +VP  R     A QE+  RA        AA RSS + RQP   AA  A   W R  R   
Sbjct: 50  RVPSVRSCALGAGQEQLARAAQPVGPLGAAGRSSGKPRQPTGAAAAAATSTWSRGPRGLG 109

Query: 181 KANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTT--PRSGKDKRRSSK 238
             + +A  + RA P A     A A +     +A  G    V+E  T  P  G  + + + 
Sbjct: 110 IPD-QACASSRADPGAS---LAAASQAVCGRSAGHGLPPGVQEARTLRPDGGALRAQEAI 165

Query: 239 PREEKQEPKKP 249
           PRE +Q P +P
Sbjct: 166 PREPRQPPPEP 176



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 53/237 (22%), Positives = 81/237 (34%), Gaps = 33/237 (13%)

Query: 17  GGSGAMAEAPGPSGESRGHSA-----TQLPAEKTVGGPSRGCSSS-------VLRVSQLV 64
           G  GA   + G   +  G +A     T     + +G P + C+SS       +   SQ V
Sbjct: 74  GPLGAAGRSSGKPRQPTGAAAAAATSTWSRGPRGLGIPDQACASSRADPGASLAAASQAV 133

Query: 65  LQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRVSGSDAAGYFRVW- 123
               + H         + LR  G  +R +      PR       L+        + ++W 
Sbjct: 134 CGRSAGHGLPPGVQEARTLRPDGGALRAQEAIPREPRQPPPEPELQCR-LQVVRWLQLWQ 192

Query: 124 -KVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKA 182
            ++P  R  P  A       A W     P    RRR   +         W     A+   
Sbjct: 193 PRIPSSRLAPISADPGGDAVAKWG--CGPSGGTRRRSTTQP------HPWAAEGPARGTP 244

Query: 183 NARARRTRRARPRAKEPPCARAK----------EEAGATAADEGRGQAVKEDTTPRS 229
           +  +   RRAR R    P  RA+            + ATAA  GR +A +  + PR+
Sbjct: 245 SVGSLWKRRARGRQLNRPWGRARLALQGAPPSRGTSAATAACTGRARAARAVSLPRA 301


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 41.2 bits (95), Expect = 9e-04
 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 8/123 (6%)

Query: 133 GRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREVWRRNARAKAKANARARRTRRA 192
           G   +EE TR         R  R R +  R+   + R+   R  +   +A ARA R   A
Sbjct: 592 GTTDREEATRLLAEKRRQAREQREREEQERRLQAE-RDKRMREEQLAREAEARAEREAEA 650

Query: 193 RPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKPRE---EKQEPKKP 249
           R R ++     A+E+A A   ++ R Q  KE+   RS ++  R    RE   ++QE ++ 
Sbjct: 651 RRREEQ----EAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQ 706

Query: 250 AQR 252
            +R
Sbjct: 707 ERR 709



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 30/133 (22%), Positives = 50/133 (37%), Gaps = 9/133 (6%)

Query: 126 PKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKA------REVWRRNARAK 179
           P     P    +  G   P   P   R  RR  QP   A   +      +EV +   R K
Sbjct: 81  PPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHK 140

Query: 180 AKANARARRTRRARPRAKEPPCARAKEEAGATAADEGRGQAVKEDTTPRSGKDKRRSSKP 239
               A+ RR  RA+  A +      KEE      ++   +  +     R   ++RR++  
Sbjct: 141 L---AKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALE 197

Query: 240 REEKQEPKKPAQR 252
             ++Q+ +K  +R
Sbjct: 198 ERQRQKLEKNKER 210


>gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 61/244 (25%), Positives = 83/244 (34%), Gaps = 44/244 (18%)

Query: 3   QALTGEAQSRWPRRGG-----SGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRG----- 52
           ++L  ++ +  PRRGG       A    P P     GH+  +       G P  G     
Sbjct: 80  ESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGER-------GSPGAGDVNPV 132

Query: 53  -CSSSVLRVSQLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRV 111
             SS   R   L+L       G T A                 GR   P G A+ T L  
Sbjct: 133 SASSPPGRPDPLLLTTFVFPPGKTSAPRPSP-----------GGRRGRPLGAARGTGLNP 181

Query: 112 SGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREV 171
             S         ++ +PR      R +  +RA W T  AP  SRRR     + +R+ R  
Sbjct: 182 GLSP--------RLQEPRGHQSARRTDTASRAGWATRRAP--SRRRNFGAPRGSRRLRPD 231

Query: 172 WRRNARAKAKANARARRTRRA-----RPRAKEPPCARAKEEAGATAADEGRGQAVKEDTT 226
             +   A      RA    R       PR++ P  A   E  G +    G G +      
Sbjct: 232 AGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQV 291

Query: 227 PRSG 230
           PRSG
Sbjct: 292 PRSG 295


>gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 61/244 (25%), Positives = 83/244 (34%), Gaps = 44/244 (18%)

Query: 3   QALTGEAQSRWPRRGG-----SGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRG----- 52
           ++L  ++ +  PRRGG       A    P P     GH+  +       G P  G     
Sbjct: 80  ESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGER-------GSPGAGDVNPV 132

Query: 53  -CSSSVLRVSQLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRV 111
             SS   R   L+L       G T A                 GR   P G A+ T L  
Sbjct: 133 SASSPPGRPDPLLLTTFVFPPGKTSAPRPSP-----------GGRRGRPLGAARGTGLNP 181

Query: 112 SGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREV 171
             S         ++ +PR      R +  +RA W T  AP  SRRR     + +R+ R  
Sbjct: 182 GLSP--------RLQEPRGHQSARRTDTASRAGWATRRAP--SRRRNFGAPRGSRRLRPD 231

Query: 172 WRRNARAKAKANARARRTRRA-----RPRAKEPPCARAKEEAGATAADEGRGQAVKEDTT 226
             +   A      RA    R       PR++ P  A   E  G +    G G +      
Sbjct: 232 AGKFPEASGGKGQRAAGAERVLDNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQV 291

Query: 227 PRSG 230
           PRSG
Sbjct: 292 PRSG 295


>gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 61/244 (25%), Positives = 83/244 (34%), Gaps = 44/244 (18%)

Query: 3   QALTGEAQSRWPRRGG-----SGAMAEAPGPSGESRGHSATQLPAEKTVGGPSRG----- 52
           ++L  ++ +  PRRGG       A    P P     GH+  +       G P  G     
Sbjct: 80  ESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGER-------GSPGAGDVNPV 132

Query: 53  -CSSSVLRVSQLVLQAISTHKGLTLAALKKELRNAGYEVRRKSGRHEAPRGQAKATLLRV 111
             SS   R   L+L       G T A                 GR   P G A+ T L  
Sbjct: 133 SASSPPGRPDPLLLTTFVFPPGKTSAPRPSP-----------GGRRGRPLGAARGTGLNP 181

Query: 112 SGSDAAGYFRVWKVPKPRRKPGRARQEEGTRAPWRTPAAPRSSRRRRQPLRKAARKAREV 171
             S         ++ +PR      R +  +RA W T  AP  SRRR     + +R+ R  
Sbjct: 182 GLSP--------RLQEPRGHQSARRTDTASRAGWATRRAP--SRRRNFGAPRGSRRLRPD 231

Query: 172 WRRNARAKAKANARARRTRRA-----RPRAKEPPCARAKEEAGATAADEGRGQAVKEDTT 226
             +   A      RA    R       PR++ P  A   E  G +    G G +      
Sbjct: 232 AGKFPEASGGKGQRAAGAERVLDNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQV 291

Query: 227 PRSG 230
           PRSG
Sbjct: 292 PRSG 295


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.125    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,020,450
Number of Sequences: 37866
Number of extensions: 556685
Number of successful extensions: 5168
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 156
Number of HSP's successfully gapped in prelim test: 397
Number of HSP's that attempted gapping in prelim test: 3948
Number of HSP's gapped (non-prelim): 1214
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.