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Search of human proteins with 31652264
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31652264 RNA binding motif protein 26 [Homo sapiens]
(980 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31652264 RNA binding motif protein 26 [Homo sapiens] 1981 0.0
gi|168229174 RNA binding motif protein 27 [Homo sapiens] 768 0.0
gi|56549694 enabled homolog isoform a [Homo sapiens] 86 2e-16
gi|39930375 enabled homolog isoform b [Homo sapiens] 86 2e-16
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 80 9e-15
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 80 1e-14
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 80 1e-14
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 79 2e-14
gi|160707881 formin 2 [Homo sapiens] 77 8e-14
gi|157168329 formin 1 [Homo sapiens] 76 1e-13
gi|47132519 Ras association and pleckstrin homology domains 1 is... 74 7e-13
gi|146134388 YLP motif containing 1 [Homo sapiens] 74 7e-13
gi|7706501 WW domain binding protein 11 [Homo sapiens] 72 2e-12
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 72 2e-12
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 72 2e-12
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 71 6e-12
gi|116812577 LUC7-like 2 [Homo sapiens] 70 1e-11
gi|52426743 cisplatin resistance-associated overexpressed protei... 70 1e-11
gi|19923485 cisplatin resistance-associated overexpressed protei... 70 1e-11
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 69 2e-11
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 69 2e-11
gi|210032580 SET domain containing 1B [Homo sapiens] 69 2e-11
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 69 2e-11
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 69 2e-11
gi|150417989 cyclin K isoform 1 [Homo sapiens] 69 2e-11
gi|153792074 proline rich 12 [Homo sapiens] 69 2e-11
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 69 3e-11
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 68 4e-11
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 67 6e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 8e-11
>gi|31652264 RNA binding motif protein 26 [Homo sapiens]
Length = 980
Score = 1981 bits (5132), Expect = 0.0
Identities = 980/980 (100%), Positives = 980/980 (100%)
Query: 1 MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVF 60
MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVF
Sbjct: 1 MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVF 60
Query: 61 LQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKF 120
LQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKF
Sbjct: 61 LQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKF 120
Query: 121 SRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYS 180
SRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYS
Sbjct: 121 SRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYS 180
Query: 181 RSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSVPS 240
RSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSVPS
Sbjct: 181 RSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSVPS 240
Query: 241 ISSGHYPVPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEK 300
ISSGHYPVPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEK
Sbjct: 241 ISSGHYPVPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEK 300
Query: 301 GFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNL 360
GFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNL
Sbjct: 301 GFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNL 360
Query: 361 RPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPP 420
RPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPP
Sbjct: 361 RPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPP 420
Query: 421 SLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSS 480
SLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSS
Sbjct: 421 SLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSS 480
Query: 481 MRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVP 540
MRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVP
Sbjct: 481 MRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVP 540
Query: 541 PELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIK 600
PELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIK
Sbjct: 541 PELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIK 600
Query: 601 VYWHREGSTQQLQTTSPKPLVQQPILPVVKQSVKERLGPVPSSTIEPAEAQSASSDLPQV 660
VYWHREGSTQQLQTTSPKPLVQQPILPVVKQSVKERLGPVPSSTIEPAEAQSASSDLPQV
Sbjct: 601 VYWHREGSTQQLQTTSPKPLVQQPILPVVKQSVKERLGPVPSSTIEPAEAQSASSDLPQV 660
Query: 661 LSTSTGLTKTVYNPAALKAAQKTLLVSTSAVDNNEAQKKKQEALKLQQDVRKRKQEILEK 720
LSTSTGLTKTVYNPAALKAAQKTLLVSTSAVDNNEAQKKKQEALKLQQDVRKRKQEILEK
Sbjct: 661 LSTSTGLTKTVYNPAALKAAQKTLLVSTSAVDNNEAQKKKQEALKLQQDVRKRKQEILEK 720
Query: 721 HIETQKMLISKLEKNKTMKSEDKAEIMKTLEVLTKNITKLKDEVKAASPGRCLPKSIKTK 780
HIETQKMLISKLEKNKTMKSEDKAEIMKTLEVLTKNITKLKDEVKAASPGRCLPKSIKTK
Sbjct: 721 HIETQKMLISKLEKNKTMKSEDKAEIMKTLEVLTKNITKLKDEVKAASPGRCLPKSIKTK 780
Query: 781 TQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHSRGRGAV 840
TQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHSRGRGAV
Sbjct: 781 TQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHSRGRGAV 840
Query: 841 HGRGRGRGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLH 900
HGRGRGRGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLH
Sbjct: 841 HGRGRGRGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDSSLH 900
Query: 901 AVITFKTRAEAEAAAVHGARFKGQDLKLAWNKPVTNISAVETEEVEPDEEEFQEESLVDD 960
AVITFKTRAEAEAAAVHGARFKGQDLKLAWNKPVTNISAVETEEVEPDEEEFQEESLVDD
Sbjct: 901 AVITFKTRAEAEAAAVHGARFKGQDLKLAWNKPVTNISAVETEEVEPDEEEFQEESLVDD 960
Query: 961 SLLQDDDEEEEDNESRSWRR 980
SLLQDDDEEEEDNESRSWRR
Sbjct: 961 SLLQDDDEEEEDNESRSWRR 980
>gi|168229174 RNA binding motif protein 27 [Homo sapiens]
Length = 1060
Score = 768 bits (1984), Expect = 0.0
Identities = 490/1129 (43%), Positives = 635/1129 (56%), Gaps = 222/1129 (19%)
Query: 5 MIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKE 64
M+IE+ +ALKSWL+K LEPICDADPSALA YV+ALVKKDK EKELKA C DQLDVFLQKE
Sbjct: 1 MLIEDVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELKAFCADQLDVFLQKE 60
Query: 65 TQIFVEKLFDAVNTKSYLP--PPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSR 122
T FV+KLF+++ TK+YLP P +P L QEK+ KEE+ +E E++ R
Sbjct: 61 TSGFVDKLFESLYTKNYLPLLEPVKPEPKPLV------QEKEEIKEEVFQEPAEEERDGR 114
Query: 123 RLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRS 182
+ + PQ + R E+K++D + RDYDR R + YR++Y+ RRGRS+S S+S
Sbjct: 115 KKKYPSPQKTRSESSERRTREKKRED-GKWRDYDRYYERNELYREKYDWRRGRSKSRSKS 173
Query: 183 RSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSVPSIS 242
R S S+ R R R +DR R+ RER K+ +R D LE++Y PVS+ P S
Sbjct: 174 RGLSRSRSRSRGRSKDRDPNRN---VEHRERS----KFKSERND-LESSYVPVSAPPPNS 225
Query: 243 SGHYP--VPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEK 300
S Y ++ ST+TVIAP HH NTTESWS ++ + NS+ R PK+RCRDYDE+
Sbjct: 226 SEQYSSGAQSIPSTVTVIAPAHHSENTTESWSNYYNNHSSSNSFGRNLPPKRRCRDYDER 285
Query: 301 GFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNL 360
GFC+ GD+C FDHG+DP+VV++V LP M+PFP PPPPGLPPP PPP L
Sbjct: 286 GFCVLGDLCQFDHGNDPLVVDEVALPSMIPFP--------PPPPGLPPP-----PPPGML 332
Query: 361 RPPVPPPGPLP-PSLPPVTGPPP-------------------------PLPPL-QPSGMD 393
PP+P PGP P P P GP P P PP+ Q S ++
Sbjct: 333 MPPMPGPGPGPGPGPGPGPGPGPGPGHSMRLPVPQGHGQPPPSVVLPIPRPPITQSSLIN 392
Query: 394 APPNSATSSVPTVVTTGIHHQPP------------------------------PAPPSLF 423
+ TS+VP + + G PP PP L
Sbjct: 393 SRDQPGTSAVPNLASVGTRLPPPLPQNLLYTVSERQPMYSREHGAAASERLQLGTPPPLL 452
Query: 424 TADT------------YDTDGYNPEAPSITNTSRP----------------MYRH---RV 452
A Y T +P P + +T P YR R
Sbjct: 453 AARLVPPRNLMGSSIGYHTSVSSP-TPLVPDTYEPDGYNPEAPSITSSGRSQYRQFFSRT 511
Query: 453 HAQRPNLIGLTSGDMDLPPR-------EKPP-----NKSSMRIVVDSESRKRTIGSGEPG 500
QRPNLIGLTSGDMD+ PR +PP N + R+V++ +SRKR + SG G
Sbjct: 512 QTQRPNLIGLTSGDMDVNPRAANIVIQTEPPVPVSINSNITRVVLEPDSRKRAM-SGLEG 570
Query: 501 VPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNEHFSRFGTLV 560
TKK W K N N PGF +K Q+ NTKLE++K+P ELNNI+KLNEHFS+FGT+V
Sbjct: 571 PLTKKPWLGKQGNNNQNKPGFLRKNQY--TNTKLEVKKIPQELNNITKLNEHFSKFGTIV 628
Query: 561 NLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIKVYWHREGS------------ 608
N+QVA+ GDPE ALIQ+ T EEA+KAISSTEAVLNNRFI+V WHRE +
Sbjct: 629 NIQVAFKGDPEAALIQYLTNEEARKAISSTEAVLNNRFIRVLWHRENNEQPTLQSSAQLL 688
Query: 609 TQQLQTTS---------PKPLVQQPIL--------------------------PVVKQSV 633
QQ QT S P+ L QQ +L + K V
Sbjct: 689 LQQQQTLSHLSQQHHHLPQHLHQQQVLVAQSAPSTVHGGIQKMMSKPQTSGAYVLNKVPV 748
Query: 634 KERLGPVPSSTIEPAEA--QSASSDLPQVLSTSTGLTKTVYNPAALKAAQKTLLVSTSAV 691
K RLG + + + QS + + ++ G K +Y+ + LK K L + +
Sbjct: 749 KHRLGHAGGNQSDASHLLNQSGGAGEDCQIFSTPGHPKMIYSSSNLKTPSK-LCSGSKSH 807
Query: 692 DNNEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDKAEIMKTLE 751
D E KKKQEA+KLQQD+RK++QE+LEK IE QKMLISKLEKNK MK E++A IMKTL+
Sbjct: 808 DVQEVLKKKQEAMKLQQDMRKKRQEVLEKQIECQKMLISKLEKNKNMKPEERANIMKTLK 867
Query: 752 VLTKNITKLKDEVKAASPGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKY 811
L + I++LKDE+K +S P +KTKT+ QKELLDTELDL+K++ +GE+ TELR+K
Sbjct: 868 ELGEKISQLKDELKTSS-AVSTPSKVKTKTEAQKELLDTELDLHKRLSSGEDTTELRKKL 926
Query: 812 TELQLEAAKRGILSSGRGRGIHSRGRGAVHGRGRGRGRGRGVPGHAVVDHRPRALEISAF 871
++LQ+EAA+ GIL GRG+ + S+GRG GRGRG GRGRG H VVDHRP+AL + F
Sbjct: 927 SQLQVEAARLGILPVGRGKTMSSQGRG--RGRGRG-GRGRGSLNHMVVDHRPKALTVGGF 983
Query: 872 TESDREDLLPHFAQYGEIEDCQIDDSSLHAVITFKTRAEAEAAAVHGARFKGQDLKLAWN 931
E ++EDLL HF + A G +FK + L+++W+
Sbjct: 984 IEEEKEDLLQHF-----------------------------STANQGPKFKDRRLQISWH 1014
Query: 932 KPVTNISAVETEEVEPDEEEFQEESLVDDSLLQDDDEEEEDNESRSWRR 980
KP + ETEE E EEE + L L DDDE+E++ ESRSWRR
Sbjct: 1015 KPKVPSISTETEEEEVKEEETETSDLF---LPDDDDEDEDEYESRSWRR 1060
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 85.9 bits (211), Expect = 2e-16
Identities = 81/323 (25%), Positives = 121/323 (37%), Gaps = 83/323 (25%)
Query: 85 PEQPSSGSLKVEFFPHQEK-DIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDE 143
P Q S +V+ P QE+ +I++ ++ +E++R+K+ R R R E
Sbjct: 121 PRQNSQLPAQVQNGPSQEELEIQRRQL-QEQQRQKELERERLERERMERERLERERLERE 179
Query: 144 RKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTR 203
R + +R + +R R+ ++R R+ R R +ER ++R+R
Sbjct: 180 RLERERLEQEQLERERQERER-QERLERQERLERQERLERQERLDRERQERQERERLERL 238
Query: 204 SRSRT-RSRERDLVKPKYDLDRTDPLENNYTPVS--------------SVPSISSGHYPV 248
R R R R+ L + + + +R + + P S S P + + P
Sbjct: 239 ERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPA 298
Query: 249 PTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEKGFCMRGDM 308
T S V+ P + PP P
Sbjct: 299 ETPSQQGIVLGP------------------------LAPPPP------------------ 316
Query: 309 CPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPG 368
P + P PAQ V PPPPG PPPPP+ + P PP PPP
Sbjct: 317 -----------------PPLPPGPAQASVAL-PPPPGPPPPPPLPSTGP----PPPPPPP 354
Query: 369 PLPPSLPPVTGPPPPLPPLQPSG 391
PLP +PP PPPP PPL SG
Sbjct: 355 PLPNQVPP-PPPPPPAPPLPASG 376
Score = 60.8 bits (146), Expect = 6e-09
Identities = 38/91 (41%), Positives = 43/91 (47%), Gaps = 22/91 (24%)
Query: 332 PAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPV-PPPGPLPPSLPPVTGPPPPLPPLQ-P 389
P+Q +V GP P PPPP L P P + PPPGP PP P TGPPPP PP P
Sbjct: 301 PSQQGIVLGPLAP---PPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLP 357
Query: 390 SGMDAPPNSATSSVPTVVTTGIHHQPPPAPP 420
+ + PP PPPAPP
Sbjct: 358 NQVPPPP-----------------PPPPAPP 371
Score = 33.9 bits (76), Expect = 0.77
Identities = 24/55 (43%), Positives = 27/55 (49%), Gaps = 8/55 (14%)
Query: 370 LPPSLPPVTGPPPPLP--PLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSL 422
L P PP PPPPLP P Q S + PP P + +TG PPP PP L
Sbjct: 308 LGPLAPP---PPPPLPPGPAQAS-VALPPPPGPPPPPPLPSTG--PPPPPPPPPL 356
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 85.9 bits (211), Expect = 2e-16
Identities = 81/323 (25%), Positives = 121/323 (37%), Gaps = 83/323 (25%)
Query: 85 PEQPSSGSLKVEFFPHQEK-DIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDE 143
P Q S +V+ P QE+ +I++ ++ +E++R+K+ R R R E
Sbjct: 121 PRQNSQLPAQVQNGPSQEELEIQRRQL-QEQQRQKELERERLERERMERERLERERLERE 179
Query: 144 RKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTR 203
R + +R + +R R+ ++R R+ R R +ER ++R+R
Sbjct: 180 RLERERLEQEQLERERQERER-QERLERQERLERQERLERQERLDRERQERQERERLERL 238
Query: 204 SRSRT-RSRERDLVKPKYDLDRTDPLENNYTPVS--------------SVPSISSGHYPV 248
R R R R+ L + + + +R + + P S S P + + P
Sbjct: 239 ERERQERERQEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPA 298
Query: 249 PTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEKGFCMRGDM 308
T S V+ P + PP P
Sbjct: 299 ETPSQQGIVLGP------------------------LAPPPP------------------ 316
Query: 309 CPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPG 368
P + P PAQ V PPPPG PPPPP+ + P PP PPP
Sbjct: 317 -----------------PPLPPGPAQASVAL-PPPPGPPPPPPLPSTGP----PPPPPPP 354
Query: 369 PLPPSLPPVTGPPPPLPPLQPSG 391
PLP +PP PPPP PPL SG
Sbjct: 355 PLPNQVPP-PPPPPPAPPLPASG 376
Score = 60.8 bits (146), Expect = 6e-09
Identities = 38/91 (41%), Positives = 43/91 (47%), Gaps = 22/91 (24%)
Query: 332 PAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPV-PPPGPLPPSLPPVTGPPPPLPPLQ-P 389
P+Q +V GP P PPPP L P P + PPPGP PP P TGPPPP PP P
Sbjct: 301 PSQQGIVLGPLAP---PPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLP 357
Query: 390 SGMDAPPNSATSSVPTVVTTGIHHQPPPAPP 420
+ + PP PPPAPP
Sbjct: 358 NQVPPPP-----------------PPPPAPP 371
Score = 33.9 bits (76), Expect = 0.77
Identities = 24/55 (43%), Positives = 27/55 (49%), Gaps = 8/55 (14%)
Query: 370 LPPSLPPVTGPPPPLP--PLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSL 422
L P PP PPPPLP P Q S + PP P + +TG PPP PP L
Sbjct: 308 LGPLAPP---PPPPLPPGPAQAS-VALPPPPGPPPPPPLPSTG--PPPPPPPPPL 356
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 80.1 bits (196), Expect = 9e-15
Identities = 49/132 (37%), Positives = 70/132 (53%), Gaps = 2/132 (1%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPP 160
+E++ ++E +E ERE++ R + R R+ R RD K+ DR R R+ DR+
Sbjct: 312 RERERERERERREREREREREREREKEKERERERERD-RDRDRTKERDRDRDRERDRDRD 370
Query: 161 RRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKY 220
R S +R R R +S R R R +ER RER+R+R R R R R R RER+ K K
Sbjct: 371 RERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDK- 429
Query: 221 DLDRTDPLENNY 232
DR + E+ Y
Sbjct: 430 KRDREEDEEDAY 441
Score = 77.8 bits (190), Expect = 5e-14
Identities = 48/116 (41%), Positives = 72/116 (62%), Gaps = 8/116 (6%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPP 160
+ ++I+KE +E ERE++ RR + R RE R R++ K+ +R R+RD DR+
Sbjct: 301 ERQEIEKERRERERERERERERR-----ERERERERE-REREKEKERERERERDRDRDRT 354
Query: 161 R-RDSYRDRY-NRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERD 214
+ RD RDR +R R R RS R++ RS S+E+ R+R+R+R R R R R R RER+
Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERE 410
Score = 71.6 bits (174), Expect = 3e-12
Identities = 45/130 (34%), Positives = 65/130 (50%), Gaps = 3/130 (2%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRE-NRSRDERKKDDRSRKRDYDRNP 159
+E+ ++ E +E EREK+ R + R +E +R RD + DR R+R DRN
Sbjct: 320 RERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK 379
Query: 160 PRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPK 219
R S +R R R R R R R +ER RER+R+R R R R R + ++RD + +
Sbjct: 380 DRSRSREKSRDRERERERERERERERE--REREREREREREREREREREKDKKRDREEDE 437
Query: 220 YDLDRTDPLE 229
D LE
Sbjct: 438 EDAYERRKLE 447
Score = 67.8 bits (164), Expect = 5e-11
Identities = 42/125 (33%), Positives = 66/125 (52%), Gaps = 4/125 (3%)
Query: 92 SLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSR 151
S ++ F K +++E+ KE+ER++ R + R RE R R+ ++ +R R
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERE--RERERERERRERERERERERER 335
Query: 152 KRDYDRNPPR-RDSYRDRYNRR-RGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTR 209
+++ +R R RD RDR R R R R R R R S +R ++R R R ++R R R R
Sbjct: 336 EKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER 395
Query: 210 SRERD 214
RER+
Sbjct: 396 ERERE 400
Score = 62.0 bits (149), Expect = 3e-09
Identities = 37/118 (31%), Positives = 59/118 (50%), Gaps = 15/118 (12%)
Query: 102 EKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPR 161
++D+ EI+K + KK + ++ + R E +K+ R R+R+ +R R
Sbjct: 273 KRDLISREISKFRDTHKKLEEE----------KGKKEKERQEIEKERRERERERERERER 322
Query: 162 RDSYRDRYNRR-----RGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERD 214
R+ R+R R + R R R R R +KER R+RDR+R R R R R+ R +D
Sbjct: 323 REREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380
Score = 54.7 bits (130), Expect = 4e-07
Identities = 37/119 (31%), Positives = 58/119 (48%), Gaps = 14/119 (11%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPP 160
+E+D ++ TKE +R++ R + +SS R ++ RSR K DR R+R+ +R
Sbjct: 345 RERDRDRDR-TKERDRDRDRERDRDRDRERSSDRNKD-RSRSREKSRDRERERERER--- 399
Query: 161 RRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPK 219
R R R R R R R +ER RER++D+ R R + ER ++ K
Sbjct: 400 ---------EREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK 449
Score = 51.2 bits (121), Expect = 5e-06
Identities = 33/129 (25%), Positives = 62/129 (48%), Gaps = 8/129 (6%)
Query: 106 KKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSY 165
+ E +++ ERE++ R + R RE R R+ ++ +R + + DR D+Y
Sbjct: 383 RSREKSRDRERERERERERERERERERERERE-REREREREREREKDKKRDREEDEEDAY 441
Query: 166 RDRYNRRRGRSRSYS-RSRSRSW---SKERLRERDRDRSRTRSRSRTRSRERDLVK---P 218
R R+ R + + + R ++W +++ RE +++ R R R ++E +K
Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501
Query: 219 KYDLDRTDP 227
YD DR DP
Sbjct: 502 DYDDDRDDP 510
Score = 43.5 bits (101), Expect = 0.001
Identities = 25/63 (39%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 350 PPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTT 409
PP L PP+ + P PPG PP P P PP P+ P M + T VPTV
Sbjct: 4 PPHLNRPPMGI--PALPPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTVSMV 61
Query: 410 GIH 412
G H
Sbjct: 62 GKH 64
Score = 38.9 bits (89), Expect = 0.024
Identities = 49/250 (19%), Positives = 94/250 (37%), Gaps = 43/250 (17%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPP 160
+ ++ ++ E+ KE +R K+F ++ + +Y + +R +D R+ +
Sbjct: 480 EREEERRREMAKEAKRLKEFLE--DYDDDRDDPKYYRGSALQKRLRD-----REKEMEAD 532
Query: 161 RRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRT-RSRSRTRSRERDLVKPK 219
RD R++ R R + ++ + E++ +R R + + S E + K +
Sbjct: 533 ERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQE 592
Query: 220 YDLDRTDPLENN------------YTPVSSVPSISSGH----YPVPTLSSTITVIAPTHH 263
+ R +P+E P+SS PS+SS P S +I P H
Sbjct: 593 KEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIP--H 650
Query: 264 GNNTTESWSEFHEDQV-------------DHNSYVRPPMPK----KRCRDYDEKGFCMRG 306
N+ + E H ++ NS R +P + D D +
Sbjct: 651 ENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKR 710
Query: 307 DMCPFDHGSD 316
+ P D+G D
Sbjct: 711 KLVPLDYGED 720
Score = 35.0 bits (79), Expect = 0.34
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 323 VNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPP-PVNLRPPVPPPGPLPPSLPPV 377
+N P M PA PP + P PG PPP P TP PV + P P L P++ V
Sbjct: 7 LNRPPM-GIPALPPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTVSMV 61
Score = 34.3 bits (77), Expect = 0.59
Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 9/46 (19%)
Query: 335 PPVVEGPP------PPGLPPPPPILTPPPVNLRPPVPPPGPLPPSL 374
PP + PP PPG+PPP PPPV PP P P+P S+
Sbjct: 4 PPHLNRPPMGIPALPPGIPPPQFPGFPPPV---PPGTPMIPVPMSI 46
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 79.7 bits (195), Expect = 1e-14
Identities = 102/403 (25%), Positives = 149/403 (36%), Gaps = 91/403 (22%)
Query: 83 PPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRD 142
PP +QP S + + P +K ++E+ E+ ++ R ++ + R++RSR
Sbjct: 373 PPVQQPFQASFQAQNEPLTQKP-HQQEMEVEQPCIQEVKRHMSDN--------RKSRSRS 423
Query: 143 ERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSR- 201
+ R R R R S R R+ R R RSR R RS S+ER R+R+++R R
Sbjct: 424 ASRSPKRRRSRSGSR------SRRSRHRRSRSRSRDRRRHSPRSRSQER-RDREKERERR 476
Query: 202 ----------TRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSV---PSISSGHYPV 248
T S T L K D LE + P+ S+ P + +
Sbjct: 477 QKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEE-FGPIESINMIPPRGCAYIVM 535
Query: 249 PTLSSTITVIAPTHHGNNTTE------SWSEFHEDQVDHNSYVRPPM-----PKKRCRDY 297
+ GN +W+ + D+ Y + P + +
Sbjct: 536 VHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKPE 595
Query: 298 DEKGFCMRGDMCPFDH--------------------GSDPVVVEDVN-LPGMLPFPAQPP 336
+ + FC G M D G++ E V+ +P LP P P
Sbjct: 596 ELESFC-EGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPI 654
Query: 337 VVEGP---PPPGLPP-----------PPPILTPP----PVNLRPPVPPPGPLPP------ 372
V P PPP +PP PP TPP P P VPPP P PP
Sbjct: 655 PVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGF 714
Query: 373 ---SLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIH 412
LPP PP P PP+ P PP++ S+P GI+
Sbjct: 715 NPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGIN 757
Score = 67.8 bits (164), Expect = 5e-11
Identities = 43/106 (40%), Positives = 52/106 (49%), Gaps = 10/106 (9%)
Query: 313 HGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPP--PVNLRPPVPPPGPL 370
H P VV + P P PP GP P PPPPP L P P++L P PPGP
Sbjct: 670 HQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPP 729
Query: 371 PPSLPPVTGPPPPLPPLQ-PSGMDAPPNSATSS-------VPTVVT 408
PP PPV+ PPP PP+ P+ A N T+ +PTVV+
Sbjct: 730 PPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVS 775
Score = 43.9 bits (102), Expect = 7e-04
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 10/89 (11%)
Query: 314 GSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPP----PILTPPPV--NLRPPVPPP 367
G P V + P A+P ++ PPG+PPP P++ P P+ ++ PPP
Sbjct: 818 GVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPP 877
Query: 368 GPLPPSLPPVTGPPPPLPP----LQPSGM 392
GP ++PP G P PP ++P GM
Sbjct: 878 GPGGFAMPPPHGMKGPFPPHGPFVRPGGM 906
Score = 42.0 bits (97), Expect = 0.003
Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 16/125 (12%)
Query: 83 PPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRY------R 136
PP +QP + P Q ++ +++ ++E+ R + RY R
Sbjct: 953 PPSQQPPPTQQQ----PQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDR 1008
Query: 137 ENRSRDER----KKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERL 192
+N +RD R + DR R RD + R +RDR R R R R + + KE+
Sbjct: 1009 DNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDR--ERDSRDRESRREKEEARGKEKP 1066
Query: 193 RERDR 197
DR
Sbjct: 1067 EVTDR 1071
Score = 41.6 bits (96), Expect = 0.004
Identities = 40/130 (30%), Positives = 49/130 (37%), Gaps = 29/130 (22%)
Query: 314 GSDPVVVEDVNLPGMLP-----FPAQPP-------VVEGPPPP--GLPPPPPILTPPPVN 359
G+ P ++ PGM P FP PP + GPPP G PPP
Sbjct: 836 GARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF------AMPPPHG 889
Query: 360 LRPPVPPPGPL--PPSLPPVTGP-PPPLPPLQPSGMDAPPNSATS----SVPTVVTTGIH 412
++ P PP GP P +P + GP P P P G PP P
Sbjct: 890 MKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQ 949
Query: 413 HQPPPA--PP 420
QPPP+ PP
Sbjct: 950 QQPPPSQQPP 959
Score = 30.8 bits (68), Expect = 6.5
Identities = 23/87 (26%), Positives = 31/87 (35%), Gaps = 31/87 (35%)
Query: 333 AQPPVVEGPPPPGLP-----------------------PPPPILTPPPVNLRPPVPPPGP 369
A P PPPP P P + P++ + P+PP G
Sbjct: 290 AAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQ 349
Query: 370 LP-------PSLPPVTGPP-PPLPPLQ 388
+P P PP+ P PP PP+Q
Sbjct: 350 MPGFGLLPTPPFPPMAQPVIPPTPPVQ 376
Score = 30.8 bits (68), Expect = 6.5
Identities = 32/113 (28%), Positives = 40/113 (35%), Gaps = 7/113 (6%)
Query: 341 PPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVT---GPPPPLPPLQ-PSGMDAPP 396
PP P P +T P L PGP+ P T G P L PLQ P GM P
Sbjct: 795 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPH 854
Query: 397 NSATSSVP--TVVTTGIHHQPPPAPPSLFTADTYDTDG-YNPEAPSITNTSRP 446
+P + +H PPP P + G + P P + P
Sbjct: 855 LQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMP 907
Score = 30.4 bits (67), Expect = 8.5
Identities = 29/132 (21%), Positives = 43/132 (32%), Gaps = 29/132 (21%)
Query: 339 EGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPS----------------------LPP 376
EG PPP P + + PP P P P PS L
Sbjct: 137 EGSPPP----PVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQT 192
Query: 377 VTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQ---PPPAPPSLFTADTYDTDGY 433
PP P P + + A + T+ + T T + PPP + F D Y
Sbjct: 193 FQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDY 252
Query: 434 NPEAPSITNTSR 445
+ E ++ + +
Sbjct: 253 DDEPEAVEESKK 264
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 79.7 bits (195), Expect = 1e-14
Identities = 102/403 (25%), Positives = 149/403 (36%), Gaps = 91/403 (22%)
Query: 83 PPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRD 142
PP +QP S + + P +K ++E+ E+ ++ R ++ + R++RSR
Sbjct: 388 PPVQQPFQASFQAQNEPLTQKP-HQQEMEVEQPCIQEVKRHMSDN--------RKSRSRS 438
Query: 143 ERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSR- 201
+ R R R R S R R+ R R RSR R RS S+ER R+R+++R R
Sbjct: 439 ASRSPKRRRSRSGSR------SRRSRHRRSRSRSRDRRRHSPRSRSQER-RDREKERERR 491
Query: 202 ----------TRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSV---PSISSGHYPV 248
T S T L K D LE + P+ S+ P + +
Sbjct: 492 QKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEE-FGPIESINMIPPRGCAYIVM 550
Query: 249 PTLSSTITVIAPTHHGNNTTE------SWSEFHEDQVDHNSYVRPPM-----PKKRCRDY 297
+ GN +W+ + D+ Y + P + +
Sbjct: 551 VHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKPE 610
Query: 298 DEKGFCMRGDMCPFDH--------------------GSDPVVVEDVN-LPGMLPFPAQPP 336
+ + FC G M D G++ E V+ +P LP P P
Sbjct: 611 ELESFC-EGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPI 669
Query: 337 VVEGP---PPPGLPP-----------PPPILTPP----PVNLRPPVPPPGPLPP------ 372
V P PPP +PP PP TPP P P VPPP P PP
Sbjct: 670 PVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGF 729
Query: 373 ---SLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIH 412
LPP PP P PP+ P PP++ S+P GI+
Sbjct: 730 NPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGIN 772
Score = 67.8 bits (164), Expect = 5e-11
Identities = 43/106 (40%), Positives = 52/106 (49%), Gaps = 10/106 (9%)
Query: 313 HGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPP--PVNLRPPVPPPGPL 370
H P VV + P P PP GP P PPPPP L P P++L P PPGP
Sbjct: 685 HQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPP 744
Query: 371 PPSLPPVTGPPPPLPPLQ-PSGMDAPPNSATSS-------VPTVVT 408
PP PPV+ PPP PP+ P+ A N T+ +PTVV+
Sbjct: 745 PPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVS 790
Score = 43.9 bits (102), Expect = 7e-04
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 10/89 (11%)
Query: 314 GSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPP----PILTPPPV--NLRPPVPPP 367
G P V + P A+P ++ PPG+PPP P++ P P+ ++ PPP
Sbjct: 833 GVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPP 892
Query: 368 GPLPPSLPPVTGPPPPLPP----LQPSGM 392
GP ++PP G P PP ++P GM
Sbjct: 893 GPGGFAMPPPHGMKGPFPPHGPFVRPGGM 921
Score = 42.0 bits (97), Expect = 0.003
Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 16/125 (12%)
Query: 83 PPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRY------R 136
PP +QP + P Q ++ +++ ++E+ R + RY R
Sbjct: 968 PPSQQPPPTQQQ----PQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDR 1023
Query: 137 ENRSRDER----KKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERL 192
+N +RD R + DR R RD + R +RDR R R R R + + KE+
Sbjct: 1024 DNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDR--ERDSRDRESRREKEEARGKEKP 1081
Query: 193 RERDR 197
DR
Sbjct: 1082 EVTDR 1086
Score = 41.6 bits (96), Expect = 0.004
Identities = 40/130 (30%), Positives = 49/130 (37%), Gaps = 29/130 (22%)
Query: 314 GSDPVVVEDVNLPGMLP-----FPAQPP-------VVEGPPPP--GLPPPPPILTPPPVN 359
G+ P ++ PGM P FP PP + GPPP G PPP
Sbjct: 851 GARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF------AMPPPHG 904
Query: 360 LRPPVPPPGPL--PPSLPPVTGP-PPPLPPLQPSGMDAPPNSATS----SVPTVVTTGIH 412
++ P PP GP P +P + GP P P P G PP P
Sbjct: 905 MKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQ 964
Query: 413 HQPPPA--PP 420
QPPP+ PP
Sbjct: 965 QQPPPSQQPP 974
Score = 30.8 bits (68), Expect = 6.5
Identities = 23/87 (26%), Positives = 31/87 (35%), Gaps = 31/87 (35%)
Query: 333 AQPPVVEGPPPPGLP-----------------------PPPPILTPPPVNLRPPVPPPGP 369
A P PPPP P P + P++ + P+PP G
Sbjct: 305 AAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQ 364
Query: 370 LP-------PSLPPVTGPP-PPLPPLQ 388
+P P PP+ P PP PP+Q
Sbjct: 365 MPGFGLLPTPPFPPMAQPVIPPTPPVQ 391
Score = 30.8 bits (68), Expect = 6.5
Identities = 32/113 (28%), Positives = 40/113 (35%), Gaps = 7/113 (6%)
Query: 341 PPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVT---GPPPPLPPLQ-PSGMDAPP 396
PP P P +T P L PGP+ P T G P L PLQ P GM P
Sbjct: 810 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPH 869
Query: 397 NSATSSVP--TVVTTGIHHQPPPAPPSLFTADTYDTDG-YNPEAPSITNTSRP 446
+P + +H PPP P + G + P P + P
Sbjct: 870 LQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMP 922
Score = 30.4 bits (67), Expect = 8.5
Identities = 29/132 (21%), Positives = 43/132 (32%), Gaps = 29/132 (21%)
Query: 339 EGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPS----------------------LPP 376
EG PPP P + + PP P P P PS L
Sbjct: 152 EGSPPP----PVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQT 207
Query: 377 VTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQ---PPPAPPSLFTADTYDTDGY 433
PP P P + + A + T+ + T T + PPP + F D Y
Sbjct: 208 FQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDY 267
Query: 434 NPEAPSITNTSR 445
+ E ++ + +
Sbjct: 268 DDEPEAVEESKK 279
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 79.3 bits (194), Expect = 2e-14
Identities = 102/393 (25%), Positives = 147/393 (37%), Gaps = 75/393 (19%)
Query: 83 PPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRD 142
PP +QP S + + P +K ++E+ E+ ++ R ++ + R++RSR
Sbjct: 388 PPVQQPFQASFQAQNEPLTQKP-HQQEMEVEQPCIQEVKRHMSDN--------RKSRSRS 438
Query: 143 ERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSR- 201
+ R R R R S R R+ R R RSR R RS S+ER R+R+++R R
Sbjct: 439 ASRSPKRRRSRSGSR------SRRSRHRRSRSRSRDRRRHSPRSRSQER-RDREKERERR 491
Query: 202 ----------TRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSV---PSISSGHYPV 248
T S T L K D LE + P+ S+ P + +
Sbjct: 492 QKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEE-FGPIESINMIPPRGCAYIVM 550
Query: 249 PTLSSTITVIAPTHHGNNTTE------SWSEFHEDQVDHNSYVRPPM-----PKKRCRDY 297
+ GN +W+ + D+ Y + P + +
Sbjct: 551 VHRQDAYRALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKPE 610
Query: 298 DEKGFCMRGDMCPFDH--------------------GSDPVVVEDVN-LPGMLPFPAQPP 336
+ + FC G M D G++ E V+ +P LP P P
Sbjct: 611 ELESFC-EGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPI 669
Query: 337 VVEGP---PPPGLPPPPPILTPPPVN-LRPP--VPPPGPLPPSLPPVTGPPPPLPPLQPS 390
V P PPP +PP P PP V L+PP PP G PP P PPPP PP
Sbjct: 670 PVPAPITVPPPQVPPHQP--GPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRP 727
Query: 391 G---MDAPPNSATSSVPTVVTTGIHHQPPPAPP 420
G M PP P +T + PP PP
Sbjct: 728 GFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPP 760
Score = 69.7 bits (169), Expect = 1e-11
Identities = 61/192 (31%), Positives = 75/192 (39%), Gaps = 41/192 (21%)
Query: 313 HGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPP--PVNLRPPVPPPGPL 370
H P VV + P P PP GP P PPPPP L P P++L P PPGP
Sbjct: 685 HQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPP 744
Query: 371 PPSLPPVTGPPPPLPPLQ-PSGMDAPPNSAT---------SSVPTVVTTGIHHQPPPAPP 420
PP PPV+ PPP PP+ P+ + +A S+VP T + P PP
Sbjct: 745 PPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNL-----PTPP 799
Query: 421 SLFTADTYDTDGYNP------EAPS---------ITNTSRPMYRHRVHAQRPNLIGLTSG 465
T G P +APS + RP H QR L
Sbjct: 800 VTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPL------ 853
Query: 466 DMDLPPREKPPN 477
+PPR PP+
Sbjct: 854 ---MPPRPMPPH 862
Score = 43.9 bits (102), Expect = 7e-04
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 10/89 (11%)
Query: 314 GSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPP----PILTPPPV--NLRPPVPPP 367
G P V + P A+P ++ PPG+PPP P++ P P+ ++ PPP
Sbjct: 811 GVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPP 870
Query: 368 GPLPPSLPPVTGPPPPLPP----LQPSGM 392
GP ++PP G P PP ++P GM
Sbjct: 871 GPGGFAMPPPHGMKGPFPPHGPFVRPGGM 899
Score = 42.0 bits (97), Expect = 0.003
Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 16/125 (12%)
Query: 83 PPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRY------R 136
PP +QP + P Q ++ +++ ++E+ R + RY R
Sbjct: 946 PPSQQPPPTQQQ----PQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRNDDR 1001
Query: 137 ENRSRDE----RKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERL 192
+N +RD R+ DR R RD + R +RDR R R R R + + KE+
Sbjct: 1002 DNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDR--ERDSRDRESRREKEEARGKEKP 1059
Query: 193 RERDR 197
DR
Sbjct: 1060 EVTDR 1064
Score = 41.6 bits (96), Expect = 0.004
Identities = 40/130 (30%), Positives = 49/130 (37%), Gaps = 29/130 (22%)
Query: 314 GSDPVVVEDVNLPGMLP-----FPAQPP-------VVEGPPPP--GLPPPPPILTPPPVN 359
G+ P ++ PGM P FP PP + GPPP G PPP
Sbjct: 829 GARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGF------AMPPPHG 882
Query: 360 LRPPVPPPGPL--PPSLPPVTGP-PPPLPPLQPSGMDAPPNSATS----SVPTVVTTGIH 412
++ P PP GP P +P + GP P P P G PP P
Sbjct: 883 MKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQ 942
Query: 413 HQPPPA--PP 420
QPPP+ PP
Sbjct: 943 QQPPPSQQPP 952
Score = 30.8 bits (68), Expect = 6.5
Identities = 23/87 (26%), Positives = 31/87 (35%), Gaps = 31/87 (35%)
Query: 333 AQPPVVEGPPPPGLP-----------------------PPPPILTPPPVNLRPPVPPPGP 369
A P PPPP P P + P++ + P+PP G
Sbjct: 305 AAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQ 364
Query: 370 LP-------PSLPPVTGPP-PPLPPLQ 388
+P P PP+ P PP PP+Q
Sbjct: 365 MPGFGLLPTPPFPPMAQPVIPPTPPVQ 391
Score = 30.4 bits (67), Expect = 8.5
Identities = 29/132 (21%), Positives = 43/132 (32%), Gaps = 29/132 (21%)
Query: 339 EGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPS----------------------LPP 376
EG PPP P + + PP P P P PS L
Sbjct: 152 EGSPPP----PVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQT 207
Query: 377 VTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQ---PPPAPPSLFTADTYDTDGY 433
PP P P + + A + T+ + T T + PPP + F D Y
Sbjct: 208 FQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDY 267
Query: 434 NPEAPSITNTSR 445
+ E ++ + +
Sbjct: 268 DDEPEAVEESKK 279
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 77.0 bits (188), Expect = 8e-14
Identities = 56/150 (37%), Positives = 72/150 (48%), Gaps = 22/150 (14%)
Query: 327 GMLPFPAQPPVVEGPPPP----GLPPPPPIL---TPPPVNLRPPVP----PPGPLPPSLP 375
G+ P P P V PPPP G+PPPPP+ PPP PP+P PP P PP P
Sbjct: 1172 GIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPP----PPLPGMGIPPAPAPPLPP 1227
Query: 376 PVTG-PPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYN 434
P TG PPPPL P+ SG P +S++PT G PPP P LF G
Sbjct: 1228 PGTGIPPPPLLPV--SGPPLLPQVGSSTLPTPQVCGF--LPPPLPSGLFGLGMNQDKGSR 1283
Query: 435 PEAPSITNTSRPMY--RHRVHAQRPNLIGL 462
+ +P+Y R ++H++R + L
Sbjct: 1284 KQPIEPCRPMKPLYWTRIQLHSKRDSSTSL 1313
Score = 62.8 bits (151), Expect = 2e-09
Identities = 43/105 (40%), Positives = 53/105 (50%), Gaps = 15/105 (14%)
Query: 327 GMLPFPAQPPVVEGPPPP----GLPPPPPIL---TPPPVNLRPPVPPPG-PLPPSLPPVT 378
G+ P P P V PPPP G+PPPPP+ PPP PP+P G P PP LP V
Sbjct: 1095 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP----PPLPGAGIPPPPPLPRVG 1150
Query: 379 GPPPPLPPLQPSGMDAPPNSATSSV-PTVVTTGIHHQPPPAPPSL 422
PPP PPL +G+ PP + + P G+ PPP P +
Sbjct: 1151 IPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGV 1193
Score = 62.0 bits (149), Expect = 3e-09
Identities = 43/108 (39%), Positives = 51/108 (47%), Gaps = 17/108 (15%)
Query: 327 GMLPFPAQPPVVEGPPPP----GLPPPPP-----ILTPPPV---NLRPPVPPPG---PLP 371
G+ P P P PPPP G+PPPPP I PPP+ + PP P PG P P
Sbjct: 1040 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1099
Query: 372 PSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAP 419
P LP V PPP PPL +G+ PP + +P PPP P
Sbjct: 1100 PPLPGVGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145
Score = 61.6 bits (148), Expect = 3e-09
Identities = 43/103 (41%), Positives = 51/103 (49%), Gaps = 15/103 (14%)
Query: 327 GMLPFPAQPPVVEGPPPP----GLPPPPPIL---TPPPVNLRPPVPPPG-PLPPSLPPVT 378
G+ P P P PPPP G+PPPPP+ PPP PP+P G P PP LP V
Sbjct: 1128 GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP----PPLPGAGIPPPPPLPGVG 1183
Query: 379 GPPPPLPPLQPSGMDAPPNSATSSV-PTVVTTGIHHQPPPAPP 420
PPP PPL G+ PP + + P G+ P PAPP
Sbjct: 1184 IPPP--PPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPP 1224
Score = 60.8 bits (146), Expect = 6e-09
Identities = 41/104 (39%), Positives = 49/104 (47%), Gaps = 14/104 (13%)
Query: 325 LPGM-LPFPAQPPVVEGPPPP-----GLPPPPPIL---TPPPVNLRPPVPPPGPLPPSLP 375
LPG +P P P PPPP G+PPPPP+ PPP PP+P G PP
Sbjct: 959 LPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP----PPLPGAGIPPPPPL 1014
Query: 376 PVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAP 419
P G PPP PPL +G+ PP + +P PPP P
Sbjct: 1015 PGAGIPPP-PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1057
Score = 60.8 bits (146), Expect = 6e-09
Identities = 46/120 (38%), Positives = 55/120 (45%), Gaps = 26/120 (21%)
Query: 327 GMLPFPAQPPVVEGPPPP----GLPPPPP-----ILTPPPV---NLRPPVPPPG---PLP 371
G+ P P P PPPP G+PPPPP I PPP+ + PP P PG P P
Sbjct: 1051 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1110
Query: 372 PSLPPVTGPPPPLPPLQPSGMDAPPNSATSSV---PTVVTTGIHHQPP------PAPPSL 422
P LP PPP PPL +G+ PP + + P + GI PP P PP L
Sbjct: 1111 PPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
Score = 60.1 bits (144), Expect = 1e-08
Identities = 45/125 (36%), Positives = 55/125 (44%), Gaps = 25/125 (20%)
Query: 317 PVVVEDVNLPGMLPFPAQPPVVEGPPPPGL--PPPPPI----LTPPPVNLRPPVPPPGPL 370
P+ + LP LP PP PP PG PPPPP+ + PPP +PPP PL
Sbjct: 958 PLPGAGIPLPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1014
Query: 371 P----PSLPPVTG----PPPPL--------PPLQPSGMDAPPNSATSSVPTVVTTGIHHQ 414
P P PP+ G PPPPL PPL +G+ PP + +P
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1074
Query: 415 PPPAP 419
PPP P
Sbjct: 1075 PPPPP 1079
Score = 59.3 bits (142), Expect = 2e-08
Identities = 43/108 (39%), Positives = 50/108 (46%), Gaps = 17/108 (15%)
Query: 327 GMLPFPAQPPVVEGPPPP--GL--PPPPP-----ILTPPPV---NLRPPVPPPG---PLP 371
G+LP P P PPPP G PPPPP I PPP+ + PP P PG P P
Sbjct: 930 GILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPP 989
Query: 372 PSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAP 419
P LP PPP PPL +G+ PP + +P PPP P
Sbjct: 990 PPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035
Score = 57.4 bits (137), Expect = 6e-08
Identities = 43/130 (33%), Positives = 56/130 (43%), Gaps = 27/130 (20%)
Query: 317 PVVVEDVNLPGMLPFPAQPPVVEGP-----PPPGLPPPPPI-----LTPPPVNL-RPPVP 365
P ++PG+ P PP + G P +P PPP+ L PPP L +P
Sbjct: 862 PCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIP 921
Query: 366 PPGPLPPS----LPPVTG----PPPPL--------PPLQPSGMDAPPNSATSSVPTVVTT 409
PP PLP + LPP+ G PPPPL PPL +G+ PP + +P
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981
Query: 410 GIHHQPPPAP 419
PPP P
Sbjct: 982 PGAGIPPPPP 991
Score = 57.4 bits (137), Expect = 6e-08
Identities = 41/108 (37%), Positives = 51/108 (47%), Gaps = 14/108 (12%)
Query: 327 GMLPFPAQPPVVEGPPPP--GL--PPPPPI----LTPPPVNLRPPVPPPGPLP----PSL 374
G+ P P P PPPP G PPPPP+ + PPP +PPP PLP P
Sbjct: 1007 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1066
Query: 375 PPVTGPP-PPLPPLQPSGMDAPPNSATSSV-PTVVTTGIHHQPPPAPP 420
PP+ G PP PPL +G+ PP + + P G+ PPP P
Sbjct: 1067 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP 1114
Score = 56.6 bits (135), Expect = 1e-07
Identities = 48/133 (36%), Positives = 57/133 (42%), Gaps = 40/133 (30%)
Query: 325 LPGM----LPFPA--QPPVVEG--------PPPPGL--PPPPPI---------------L 353
LPGM LP A QPP ++G PP PG PPPPP+ +
Sbjct: 883 LPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGI 942
Query: 354 TPPP----VNLRPPVPPPG---PLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTV 406
PPP + PP P PG PLPP LP PPP PPL +G+ PP + +P
Sbjct: 943 PPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPP 1000
Query: 407 VTTGIHHQPPPAP 419
PPP P
Sbjct: 1001 PPLPGAGIPPPPP 1013
Score = 52.0 bits (123), Expect = 3e-06
Identities = 43/143 (30%), Positives = 52/143 (36%), Gaps = 35/143 (24%)
Query: 312 DHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPP--------------ILTPPP 357
+H N+P P P P +PPPPP I PPP
Sbjct: 842 EHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPP 901
Query: 358 VNLRPPVPPPGPLPPSLPPVTGPPP---------PLPPLQPSGMDAP---PNSATSSVPT 405
+ +PPP PP LP PPP PLPPL +G+ P P +A P
Sbjct: 902 LQGTEMLPPP---PPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPP 958
Query: 406 VVTTGIHHQPP------PAPPSL 422
+ GI PP P PP L
Sbjct: 959 LPGAGIPLPPPLPGAGIPPPPPL 981
Score = 35.0 bits (79), Expect = 0.34
Identities = 26/57 (45%), Positives = 27/57 (47%), Gaps = 6/57 (10%)
Query: 325 LPGM----LPFPAQPPVVEG-PPPPGLPPPPPILTPPPVNLRPPVPPP-GPLPPSLP 375
LPGM P P PP G PPPP LP P L P + P P G LPP LP
Sbjct: 1212 LPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 30.4 bits (67), Expect = 8.5
Identities = 25/93 (26%), Positives = 31/93 (33%), Gaps = 27/93 (29%)
Query: 332 PAQPPVVEGPPP--------------------PGLPPPPPILT-----PPPVNLRPPVPP 366
PA PP P P PG P L+ P + P P
Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ 291
Query: 367 PGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSA 399
P P LP P LP QP+ D+P ++A
Sbjct: 292 QPPSPGGLP--VSEAPSLPAAQPAAKDSPSSTA 322
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 76.3 bits (186), Expect = 1e-13
Identities = 49/126 (38%), Positives = 62/126 (49%), Gaps = 19/126 (15%)
Query: 341 PPPPGLPPPPPI------LTP----PPVNLRPPVPPPGPLPPSLPPVT--GPPPPLPPLQ 388
PPP +PPPPP+ L+P PPV+ PP+PPP P PP LPP + GPPPP PP
Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPP 706
Query: 389 PSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNT--SRP 446
APPN P G+ PP PP LF + P P+I + +P
Sbjct: 707 LPNSPAPPNPG-GPPPAPPPPGL---APPPPPGLFFG-LGSSSSQCPRKPAIEPSCPMKP 761
Query: 447 MYRHRV 452
+Y R+
Sbjct: 762 LYWTRI 767
Score = 75.1 bits (183), Expect = 3e-13
Identities = 39/73 (53%), Positives = 41/73 (56%), Gaps = 3/73 (4%)
Query: 325 LPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPS-LPPVTGPPPP 383
L + P P PPV GPP P PPPPP L PP PP PPP PLP S PP G PPP
Sbjct: 662 LGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPP 721
Query: 384 LPPLQPSGMDAPP 396
PP P G+ PP
Sbjct: 722 APP--PPGLAPPP 732
Score = 54.7 bits (130), Expect = 4e-07
Identities = 30/55 (54%), Positives = 32/55 (58%), Gaps = 8/55 (14%)
Query: 330 PFPAQPPVVEGPPPPGLPPPPPI-LTPPPVNLRPPVPPPGPLPPSLPPVTGPPPP 383
P P PP GPPPP PPPPP+ +P P N P PPP P PP L P PPPP
Sbjct: 687 PPPLPPPSSAGPPPP--PPPPPLPNSPAPPN--PGGPPPAPPPPGLAP---PPPP 734
Score = 53.1 bits (126), Expect = 1e-06
Identities = 32/82 (39%), Positives = 36/82 (43%), Gaps = 16/82 (19%)
Query: 353 LTPPPVNLRPPVP---------PPGPLP-----PSLPPVTGPPPPLPPLQPSGMDAPPNS 398
L PPP ++ PP P P P+P P LPP PPPPLPP PS PP
Sbjct: 645 LPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPP--PSSAGPPPPP 702
Query: 399 ATSSVPTVVTTGIHHQPPPAPP 420
+P PPPAPP
Sbjct: 703 PPPPLPNSPAPPNPGGPPPAPP 724
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 73.9 bits (180), Expect = 7e-13
Identities = 67/237 (28%), Positives = 92/237 (38%), Gaps = 46/237 (19%)
Query: 330 PFPAQPPVVEGPPPPGLPPPPPILTPPPVNLR---------------PPVPPPGPLP--- 371
P P PP + P PP PP P + P P + + PPVPP P
Sbjct: 761 PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFP 820
Query: 372 -------PSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVV-TTGIHHQPPPAPPSLF 423
P PPV PPP LP Q S PP S S VP+VV PPP PP++
Sbjct: 821 ASYIPPSPPTPPVPVPPPTLPK-QQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM- 878
Query: 424 TADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREK-----PPNK 478
++ P ++ S P + + Q P+ I + S D PP E PP
Sbjct: 879 -----ESQPLKPVPANVAPQSPPAVKAKPKWQ-PSSIPVPSPDFPPPPPESSLVFPPPPP 932
Query: 479 SSMRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLE 535
S + + + G P KKT ++T+SPG +K N+ ++
Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKT-------SKTSSPGGKKPPPTPQRNSSIK 982
Score = 54.3 bits (129), Expect = 5e-07
Identities = 59/257 (22%), Positives = 84/257 (32%), Gaps = 30/257 (11%)
Query: 247 PVPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYV-----RPPMPKKRCRDYDEKG 301
P PT + T+ + T + SY+ PP+P ++
Sbjct: 786 PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQS 845
Query: 302 FCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLR 361
FC + P PV + P P PP +E P +P +PP V +
Sbjct: 846 FCAKPPPSPLS----PVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK 901
Query: 362 P-------PVPPPG--PLPPSLPPVTGPPPPLP------PLQPSGMDAPPNSATSSVPTV 406
P PVP P P PP V PPPP P P P+ P S + T
Sbjct: 902 PKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTS 961
Query: 407 VTTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGD 466
T+ + PP P ++ + +PE RP V P +
Sbjct: 962 KTSSPGGKKPPPTPQRNSSIKSSSGAEHPE------PKRPSVDSLVSKFTPPAESGSPSK 1015
Query: 467 MDLPPREKPPNKSSMRI 483
LPP PP + +
Sbjct: 1016 ETLPPPAAPPKPGKLNL 1032
Score = 53.5 bits (127), Expect = 9e-07
Identities = 34/84 (40%), Positives = 38/84 (45%), Gaps = 7/84 (8%)
Query: 344 PGLPPPPPILTPPPVNL-RPPVPPPGPLPPSLPPVTGPPPPLPPLQ--PSGMDAPPNSAT 400
P L P P I+TP + PP+PPP P PP PP PPPP P Q PS A P
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666
Query: 401 SSVPTVVTTGIHHQ----PPPAPP 420
S T + H PP PP
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPP 690
Score = 53.5 bits (127), Expect = 9e-07
Identities = 46/138 (33%), Positives = 55/138 (39%), Gaps = 32/138 (23%)
Query: 327 GMLPFPAQPPVVEG---------PPPPGLPPPPPILTPPPVNLRPPVP-------PPGPL 370
G L P PPV++ PP +PPPPP PPP PP P P P
Sbjct: 681 GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP---PPP----PPTPGSAMAQLKPAPC 733
Query: 371 PPSLPPVTGPPPPLP--PLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTY 428
PSLP + PPPPL +Q APP T P + + Q PP P A T
Sbjct: 734 APSLPQFSAPPPPLKIHQVQHITQVAPP---TPPPPPPIPAPLPPQAPPKPLVTIPAPT- 789
Query: 429 DTDGYNPEAPSITNTSRP 446
AP +T + P
Sbjct: 790 ---STKTVAPVVTQAAPP 804
Score = 53.1 bits (126), Expect = 1e-06
Identities = 49/150 (32%), Positives = 56/150 (37%), Gaps = 33/150 (22%)
Query: 330 PFPAQPPVVE----GPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLP----PVTGPP 381
P QP +V P P LPPPPP PPP PP PPP P PP LP P G
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPP---PPP----PPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 382 PPL-----------PPLQPSGM----DAPPNSATSSVP---TVVTTGIHHQPPPAPPSLF 423
P+ Q SG PP + SV V G+ PPP PP
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 424 TADTYDTDGYNPEAPSITNTSRPMYRHRVH 453
P APS+ S P ++H
Sbjct: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIH 750
Score = 39.7 bits (91), Expect = 0.014
Identities = 47/195 (24%), Positives = 72/195 (36%), Gaps = 39/195 (20%)
Query: 330 PFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLP---P 386
P + P E PPP PP P L VNL P V G + P ++G P
Sbjct: 1007 PAESGSPSKETLPPPAAPPKPGKLNLSGVNL-PGVLQQGCVSAKAPVLSGRGKDSVVEFP 1065
Query: 387 LQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNTSRP 446
PS D PP + +P PP P++F+ +T +P+ + +P
Sbjct: 1066 SPPSDSDFPPPPPETELPL---------PPIEIPAVFSGNT------SPKVAVV--NPQP 1108
Query: 447 MYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDSESRKRTIGSGEPGVPTKKT 506
++ ++ PP +P S R+ S + T+ + P VPT
Sbjct: 1109 QQWSKMSVKK------------APPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPT--- 1153
Query: 507 WFDKPNFNRTNSPGF 521
P + + PGF
Sbjct: 1154 ---SPKSSLSVQPGF 1165
Score = 35.4 bits (80), Expect = 0.26
Identities = 30/123 (24%), Positives = 44/123 (35%), Gaps = 20/123 (16%)
Query: 364 VPPPGPLP----------PSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHH 413
VPP P P PS PP+ PPPP PP P PP + S P+ +
Sbjct: 606 VPPLSPQPKIVTPYTASQPS-PPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664
Query: 414 QPPPAPPSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPRE 473
L A + + P P + + + +P ++ +G + PP
Sbjct: 665 VKYSTITRLQNASQHSGALFKPPTPPVMQS---------QSVKPQILVPPNGVVPPPPPP 715
Query: 474 KPP 476
PP
Sbjct: 716 PPP 718
Score = 31.2 bits (69), Expect = 5.0
Identities = 42/158 (26%), Positives = 55/158 (34%), Gaps = 19/158 (12%)
Query: 319 VVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPV---NLRPPVPPPGPLPPSLP 375
VVE + P FP PP E P PP + P V N P V P P
Sbjct: 1061 VVEFPSPPSDSDFPPPPPETELPLPP--------IEIPAVFSGNTSPKVAVVNPQPQQWS 1112
Query: 376 PVTGPPPPLPPLQPSGMDAP--PNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGY 433
++ P PP +P D+ + S PT+ T + Q P +P S +
Sbjct: 1113 KMSVKKAP-PPTRPKRNDSTRLTQAEISEQPTMAT--VVPQVPTSPKSSLSVQPGFLADL 1169
Query: 434 NPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPP 471
N + T R+ P T DM LPP
Sbjct: 1170 NRTLQRKSITRHGSLSSRMSRAEPT---ATMDDMALPP 1204
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 73.9 bits (180), Expect = 7e-13
Identities = 122/584 (20%), Positives = 191/584 (32%), Gaps = 167/584 (28%)
Query: 84 PPEQPSSGSLKVEFFPHQEKDIKKEE-ITKEEEREK-----KFSRRLNHSPPQSSSRYRE 137
PP + G + ++ E+D +E +E ER+ + SR ++ + +
Sbjct: 1251 PPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDR 1310
Query: 138 NRSRDERKKDDRSRKRDYDRNPPRR--------DSYRD-RYNRRRGRSRSYSRSRSRSWS 188
+ R +++ + R+RD PP D YRD R+ R R Y R
Sbjct: 1311 DYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDF----- 1365
Query: 189 KERLRERDRDRSRTRS---RSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSVPSISSGH 245
RDR R R R T +RD V + D +R + Y PS H
Sbjct: 1366 ------RDRGELRIREYPERGDTWREKRDYVPDRMDWERERLSDRWY------PSDVDRH 1413
Query: 246 YPVPTLSSTITVIAPTHHGNNTTESWSEFHEDQV----------DHNSYVRPPMPKKRCR 295
P+ + +HH + S + DQ H ++ K R
Sbjct: 1414 SPMAEHMPS------SHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLR 1467
Query: 296 DYDEKGFCMRGDMCPFDHGSDPVVVEDV-----------NLPGMLPFPA--QPPVVEG-- 340
+ E+ M+ D GS+P + + + + PGM P P +PP G
Sbjct: 1468 EQKEQLQKMK------DFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKP 1521
Query: 341 ----------------------------PPPPGLPPPPPILTP----------------- 355
PPPP LPPPPP++ P
Sbjct: 1522 PGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYG 1581
Query: 356 ---------------------------PPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQ 388
PP + +PPPGP+P +PP++ PPP +
Sbjct: 1582 LWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVD 1641
Query: 389 -PSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPE---APSITNTS 444
G D N +P + P P + T D Y+ E P S
Sbjct: 1642 YGHGRDISTNK-VEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQS 1700
Query: 445 RPMYRHR-------VHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDSESRKRTIGSG 497
+ HR H R G+ D D RE+ P + D + + G
Sbjct: 1701 NVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGG 1760
Query: 498 EPGVPTKKTWFDKPNFNR-TNSPGFQKKVQFGNENTKLELRKVP 540
FD+P+++R ++ P ++ FG E ++P
Sbjct: 1761 ----------FDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMP 1794
Score = 65.9 bits (159), Expect = 2e-10
Identities = 46/116 (39%), Positives = 56/116 (48%), Gaps = 19/116 (16%)
Query: 325 LPGMLPFPAQPPVVEGP-PPPGLPPP--PPIL--TPPPVNLRPPVPPPGPLPPSLPPVT- 378
LP LP P PP + PPPG+PPP PP L + PP + P + GP PP LPP +
Sbjct: 538 LPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGP-PPVLPPPSL 596
Query: 379 ---GPPPPLPP------LQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTA 425
GPPP LPP P M PP S+ + P + G+ P PP L A
Sbjct: 597 SSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGV---PQGIPPQLTAA 649
Score = 64.7 bits (156), Expect = 4e-10
Identities = 40/106 (37%), Positives = 53/106 (50%), Gaps = 18/106 (16%)
Query: 326 PGMLPFPAQPPVVEGPPPPGLPP--PPPILTPP-PVNLRPPVPPPGPLPPSLP---PVTG 379
P +P+ PP + PPP LPP PPP++ P P + PP PP +PPSLP P G
Sbjct: 518 PPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPG 577
Query: 380 PPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPP-----APP 420
PP L P + PP+ +++ P V+ PPP APP
Sbjct: 578 MPPSLSSAGPPPVLPPPSLSSAGPPPVL-------PPPSLSSTAPP 616
Score = 63.5 bits (153), Expect = 9e-10
Identities = 47/112 (41%), Positives = 53/112 (47%), Gaps = 20/112 (17%)
Query: 325 LPGMLPFPAQPPVVEGP------PPPGLPP------PPPILTPPPVNLRPPVPPPGPLPP 372
LP +P P PP V P PPPG+PP PPP+L PP +L PPP PP
Sbjct: 551 LPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPP--SLSSAGPPPVLPPP 608
Query: 373 SLPPVTGPPP--PLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQP-PPAPPS 421
SL T PPP PLPPL S PP VP + + P PPA S
Sbjct: 609 SLSS-TAPPPVMPLPPL--SSATPPPGIPPPGVPQGIPPQLTAAPVPPASSS 657
Score = 56.2 bits (134), Expect = 1e-07
Identities = 39/114 (34%), Positives = 51/114 (44%), Gaps = 12/114 (10%)
Query: 317 PVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPP--------PPPILTPPPVNLRPPVPPPG 368
P V +LP +P P PP + PP + P PPP+L PP ++ P PP
Sbjct: 561 PPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP-PPVM 619
Query: 369 PLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSL 422
PLPP L T PP PP P G+ PP + VP ++ P P+L
Sbjct: 620 PLPP-LSSATPPPGIPPPGVPQGI--PPQLTAAPVPPASSSQSSQVPEKPRPAL 670
Score = 53.9 bits (128), Expect = 7e-07
Identities = 44/124 (35%), Positives = 54/124 (43%), Gaps = 25/124 (20%)
Query: 317 PVVVEDVNLPGMLPFPAQPPVVEGP------PPPGLPPPPPILT-PPPVNLRPPV----P 365
P V +P L PPV+ P PPP LPPP T PPPV PP+ P
Sbjct: 570 PTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATP 629
Query: 366 PPGPLPPSLPPVTGPPP-----PLPPLQPS-GMDAPPNSATSSVPTVVTTGIHHQPPPAP 419
PPG PP +P G PP P+PP S P + +PT V+ G AP
Sbjct: 630 PPGIPPPGVP--QGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFG------SAP 681
Query: 420 PSLF 423
P+ +
Sbjct: 682 PTTY 685
Score = 50.4 bits (119), Expect = 8e-06
Identities = 28/74 (37%), Positives = 36/74 (48%), Gaps = 10/74 (13%)
Query: 326 PGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLP 385
PG++P + P P PPG PP + +PPP P PPS P T P LP
Sbjct: 136 PGLVPMELESPPESPPVPPGSYMPPS---------QSYMPPPQP-PPSYYPPTSSQPYLP 185
Query: 386 PLQPSGMDAPPNSA 399
P QPS +PP+ +
Sbjct: 186 PAQPSPSQSPPSQS 199
Score = 50.4 bits (119), Expect = 8e-06
Identities = 35/82 (42%), Positives = 40/82 (48%), Gaps = 14/82 (17%)
Query: 346 LPPP--PPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSV 403
+PPP P PPP+ P PP LPPSLPP PP + P GM PP S+
Sbjct: 516 MPPPFVPYSQMPPPL----PTMPPPVLPPSLPPPVMPPALPATVPPPGM--PPPVMPPSL 569
Query: 404 PTVVTTGIHHQPPPAPPSLFTA 425
PT V PP PPSL +A
Sbjct: 570 PTSV------PPPGMPPSLSSA 585
Score = 49.7 bits (117), Expect = 1e-05
Identities = 41/119 (34%), Positives = 57/119 (47%), Gaps = 33/119 (27%)
Query: 342 PPPGLP---PPPPILTPPPVNLRPPVPP-------PGPLPPSLPPVTGPPPPLPPLQPSG 391
PPP +P PPP+ T PP P +PP P LP ++PP PPP +PP P+
Sbjct: 517 PPPFVPYSQMPPPLPTMPP----PVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTS 572
Query: 392 MDAPPNSATSSVPTVVTTGIHHQPPPA--PPSLFTADTYDTDGYNP--EAPSITNTSRP 446
+ P P++ + G PPP PPSL +A G P PS+++T+ P
Sbjct: 573 VPPP-----GMPPSLSSAG----PPPVLPPPSLSSA------GPPPVLPPPSLSSTAPP 616
Score = 48.5 bits (114), Expect = 3e-05
Identities = 58/237 (24%), Positives = 83/237 (35%), Gaps = 72/237 (30%)
Query: 342 PPPGLPPPPPI-------LTPPPVNLRPPVPPP-GPL--------------------PPS 373
PPP LPPPP + PPP PP+PPP GP PP
Sbjct: 82 PPPPLPPPPVMPGGGYGDWQPPP----PPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137
Query: 374 LPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGY 433
L P+ PP P P G PP+ + + PPP PP + T + Y
Sbjct: 138 LVPMELESPPESPPVPPGSYMPPSQS-------------YMPPPQPPPSYYPPT-SSQPY 183
Query: 434 NPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMD--------LPPREKPPNKSSMRIVV 485
P A + S P + A P+ +S LP + P++ S
Sbjct: 184 LPPAQPSPSQSPPSQSYL--APTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPS----- 236
Query: 486 DSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPE 542
S+ + + P P N+T Q+ ++ G +N E ++ PE
Sbjct: 237 QGHSKSQLLAPPPPSAPPG---------NKTTVQ--QEPLESGAKNKSTEQQQAAPE 282
Score = 46.6 bits (109), Expect = 1e-04
Identities = 46/169 (27%), Positives = 59/169 (34%), Gaps = 72/169 (42%)
Query: 348 PPPPILTPPPVNLRPPVPPPG------PLPPS---------------------------- 373
PPPP+ PPPV L P PG P PS
Sbjct: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
Query: 374 -LPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQ----PPPAPPSLFTADTY 428
L P PPPPLPP P V+ G + PPP PP
Sbjct: 75 VLQPHHLPPPPLPP-----------------PPVMPGGGYGDWQPPPPPMPP-------- 109
Query: 429 DTDGYNPEAPSITNTSRPMYRHR-VHAQRPNLIGLTSGDMDLPPREKPP 476
P P+++ + Y+H+ +H QR GL +++ PP E PP
Sbjct: 110 ------PPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPP-ESPP 151
Score = 44.7 bits (104), Expect = 4e-04
Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 17/99 (17%)
Query: 317 PVVVEDVNLPGMLPFPAQP--PVVEGPPPPGLPPP------PPILTPPPV--------NL 360
P V+ +L P P P P+ PPPG+PPP PP LT PV +
Sbjct: 602 PPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQ 661
Query: 361 RPPVPPPGPLPPSLPPVTGPPPPL-PPLQPSGMDAPPNS 398
P P P LP + + PP PPLQ +G NS
Sbjct: 662 VPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNS 700
Score = 44.3 bits (103), Expect = 6e-04
Identities = 55/200 (27%), Positives = 77/200 (38%), Gaps = 63/200 (31%)
Query: 330 PFPAQPPVVEGPPPPGLP--------PPPPILTPPP---------------VNLRPPVPP 366
P PP + PPPP +P PPPP + PPP + P
Sbjct: 78 PHHLPPPPL--PPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP 135
Query: 367 PGPLPPSL--PPVTGPPPP----------LPPLQPSGMDAPPNSATSSVPTVVTTGIHHQ 414
PG +P L PP + P PP +PP QP PP TSS P +
Sbjct: 136 PGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPP---TSSQPYL-------- 184
Query: 415 PPPAPPSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQ-----------RPNLIGLT 463
PPA PS + + + Y PS +++S + H+Q RP+
Sbjct: 185 -PPAQPS--PSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSK 241
Query: 464 SGDMDLPPREKPP-NKSSMR 482
S + PP PP NK++++
Sbjct: 242 SQLLAPPPPSAPPGNKTTVQ 261
Score = 37.4 bits (85), Expect = 0.069
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 17/163 (10%)
Query: 80 SYLPPPEQPSSGSLKVEFFPHQEKDIKK---EEITKEEEREKKFSRRLNHSP---PQSSS 133
S +PPP G + P ++ + +I+ + + + R+ P P+ S+
Sbjct: 1615 SSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERST 1674
Query: 134 RYRENRSRDERKKDDRSRKRDYDRNP----PRRDSYRDRYNRR-RGRSRS---YSRSRSR 185
E+ + +R +R R+ +DR RD RDR R R R R Y R R
Sbjct: 1675 FETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDR-- 1732
Query: 186 SWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPL 228
+ +ER DR +S + + SR +P YD P+
Sbjct: 1733 -FDRERRPRDDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPV 1774
Score = 34.7 bits (78), Expect = 0.45
Identities = 19/68 (27%), Positives = 24/68 (35%)
Query: 347 PPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTV 406
P P P + P P PP PP PPPLPP +P D ++ +
Sbjct: 327 PEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAA 386
Query: 407 VTTGIHHQ 414
HQ
Sbjct: 387 AAHWQQHQ 394
Score = 32.3 bits (72), Expect = 2.2
Identities = 43/145 (29%), Positives = 60/145 (41%), Gaps = 14/145 (9%)
Query: 91 GSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRS 150
G +K E F ++K + + E ++E+ + SR P SS RE + DR
Sbjct: 1050 GLVKQEDF--RDKMMGRREDSREKMNRGEGSRDRGLVRPGSS---REKVPGGLQGSQDRG 1104
Query: 151 RKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKER-------LRERDRDRSR-T 202
+R PPRR ++R RR SR R R+ S+ER RER RS
Sbjct: 1105 AAGSRERGPPRRAGSQERGPLRRAGSRERIPPR-RAGSRERGPPRGPGSRERGLGRSDFG 1163
Query: 203 RSRSRTRSRERDLVKPKYDLDRTDP 227
R R R D + Y R +P
Sbjct: 1164 RDRGPFRPEPGDGGEKMYPYHRDEP 1188
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 72.4 bits (176), Expect = 2e-12
Identities = 52/149 (34%), Positives = 60/149 (40%), Gaps = 32/149 (21%)
Query: 317 PVVVEDVNLPGMLPF--PAQPPVVEGPPPPGLPPPPP---------------------IL 353
P ++ +PG P P PP+ PP GLPP PP +L
Sbjct: 399 PSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLL 458
Query: 354 TPPPVNLRPPVPPPGPLP--PSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGI 411
P P RPP PPPGP P P PP GPPP LPP P G+ PP P V G
Sbjct: 459 PPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI-PPPRPGMMRPPLVPPLG- 516
Query: 412 HHQPPPAPPSLFTADTYDTDGYNPEAPSI 440
PAPP LF G P++
Sbjct: 517 -----PAPPGLFPPAPLPNPGVLSAPPNL 540
Score = 61.6 bits (148), Expect = 3e-09
Identities = 39/92 (42%), Positives = 44/92 (47%), Gaps = 11/92 (11%)
Query: 330 PFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPP-LQ 388
P P ++ PP PG PP L PPP PP+ PPGP P LPP GPPP PP L+
Sbjct: 394 PQSVPPSQIQAPPMPGPPP----LGPPPA---PPLRPPGP-PTGLPP--GPPPGAPPFLR 443
Query: 389 PSGMDAPPNSATSSVPTVVTTGIHHQPPPAPP 420
P GM +P G PPP PP
Sbjct: 444 PPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPP 475
Score = 45.4 bits (106), Expect = 3e-04
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 12/93 (12%)
Query: 326 PGMLPFP---AQPPVVEGPPPPGLPPP------PPI---LTPPPVNLRPPVPPPGPLPPS 373
PG+ P P PP + P PPG+PPP PP+ L P P L PP P P P S
Sbjct: 476 PGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLS 535
Query: 374 LPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTV 406
PP P + ++ + S+ P +
Sbjct: 536 APPNLIQRPKADDTSAATIEKKATATISAKPQI 568
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 313 HGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPP 372
H ++++D+ LPG AQPP + PP + P + P PPG PP
Sbjct: 146 HAPSNILIQDIPLPG-----AQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPP 200
Query: 373 SLPPVTGPPPP 383
PP GPPPP
Sbjct: 201 GPPP--GPPPP 209
Score = 32.7 bits (73), Expect = 1.7
Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 318 VVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTP----PPVNLRPPVPPPGPLPPS 373
V VE + LP M P +++ P PG PP + PP +P G P
Sbjct: 134 VEVESIPLPDM-PHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPR 192
Query: 374 LPPVTGP--PPPLPP 386
LPP P PPP PP
Sbjct: 193 LPPGRKPPGPPPGPP 207
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 72.4 bits (176), Expect = 2e-12
Identities = 43/109 (39%), Positives = 64/109 (58%), Gaps = 9/109 (8%)
Query: 112 KEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNR 171
+ + +E+K SR +HS +S R +RSR+ +K RSR+R R+ R R
Sbjct: 52 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE--------R 103
Query: 172 RRGRSRSYSRSRS-RSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPK 219
++ RSRS R R RS S+ R R R R RSR+R+RSR+R R++ + KP+
Sbjct: 104 KKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPR 152
Score = 66.6 bits (161), Expect = 1e-10
Identities = 49/137 (35%), Positives = 64/137 (46%), Gaps = 23/137 (16%)
Query: 100 HQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNP 159
H+ KD ++ EE +K+ S SS + R ERK SR R + R+
Sbjct: 14 HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS---SRGRSHSRSR 70
Query: 160 PRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRS------------------- 200
R +R R +R R +SRS SR R +S S+ R R++ R RS
Sbjct: 71 SRERRHRSR-SRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 129
Query: 201 RTRSRSRTRSRERDLVK 217
RTRSRSRTRSR RD K
Sbjct: 130 RTRSRSRTRSRSRDRKK 146
Score = 56.6 bits (135), Expect = 1e-07
Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 5/94 (5%)
Query: 123 RLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRS 182
R + S +SS +++ D+ D+ R+R + + D ++ R R+ R RS+SRS
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRER-LNSSENGEDRHK-RKERKSSRGRSHSRS 69
Query: 183 RSRSW---SKERLRERDRDRSRTRSRSRTRSRER 213
RSR S+ R R++ R RSR R +SR+RSRER
Sbjct: 70 RSRERRHRSRSRERKKSRSRSRERKKSRSRSRER 103
Score = 48.9 bits (115), Expect = 2e-05
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 20/108 (18%)
Query: 107 KEEITKEEEREKKFSRRLNHSPPQSSSRYRE---NRSRD-ERKKDDRSRKRDYDRNPPRR 162
+E + RE+K SR + +S SR RE +RSR ERK+ RSR R
Sbjct: 72 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR--------- 122
Query: 163 DSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRS 210
+R R R R+ SRSR+RS S++R + ++ R +RS SRT S
Sbjct: 123 -------SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 163
Score = 44.3 bits (103), Expect = 6e-04
Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 10/163 (6%)
Query: 106 KKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPR-RDS 164
++ + ++ RE+K SR + +S SR RE + R + RSR R R+ R R
Sbjct: 81 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSR 140
Query: 165 YRDRYNRRRGRSRSYSRSRSRSWSKERLRERDR--------DRSRTRSRSRTRSRERDLV 216
RDR +R + R +SRS SR+ S R R+ R R++ RE+++V
Sbjct: 141 SRDR-KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMV 199
Query: 217 KPKYDLDRTDPLENNYTPVSSVPSISSGHYPVPTLSSTITVIA 259
+ + + + ++ ++SG P ++ + A
Sbjct: 200 EKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAA 242
Score = 33.9 bits (76), Expect = 0.77
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 145 KKDDRSRKRDYDRNPPRRDSYRDR-YNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTR 203
K+ R +D + + + D+ ++ +GR R S ++R + ++R SR R
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENG----EDRHKRKERKSSRGR 64
Query: 204 SRSRTRSRER 213
S SR+RSRER
Sbjct: 65 SHSRSRSRER 74
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 72.4 bits (176), Expect = 2e-12
Identities = 43/109 (39%), Positives = 64/109 (58%), Gaps = 9/109 (8%)
Query: 112 KEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNR 171
+ + +E+K SR +HS +S R +RSR+ +K RSR+R R+ R R
Sbjct: 111 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE--------R 162
Query: 172 RRGRSRSYSRSRS-RSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPK 219
++ RSRS R R RS S+ R R R R RSR+R+RSR+R R++ + KP+
Sbjct: 163 KKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPR 211
Score = 64.3 bits (155), Expect = 5e-10
Identities = 42/114 (36%), Positives = 56/114 (49%), Gaps = 12/114 (10%)
Query: 100 HQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNP 159
H+ KD ++ EE +K+ S SS + R ERK SR R + R+
Sbjct: 73 HESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKS---SRGRSHSRS- 128
Query: 160 PRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRER 213
R RR RSRS R +SRS S+ER + R R R R +SRSR+R R+R
Sbjct: 129 --------RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKR 174
Score = 60.8 bits (146), Expect = 6e-09
Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 9/123 (7%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKR------- 153
+ K E K R + R + S +SS +++ D+ D+ R+R
Sbjct: 49 ERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENG 108
Query: 154 -DYDRNPPRRDSYRDRYNRRRGRSRSY-SRSRSRSWSKERLRERDRDRSRTRSRSRTRSR 211
D + R+ S ++R R R R + SRSR R S+ R RER + RSR+R R ++RSR
Sbjct: 109 EDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
Query: 212 ERD 214
R+
Sbjct: 169 SRE 171
Score = 49.3 bits (116), Expect = 2e-05
Identities = 39/127 (30%), Positives = 59/127 (46%), Gaps = 15/127 (11%)
Query: 102 EKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRD---ERKKDDRSRK-RDYDR 157
E+D E T + +KK ++ SP S Y +RSR +RK D+ RK R R
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
Query: 158 NPP-RRDSYRDRYNRRRGRSRSYSRSRSRSWSKERL----------RERDRDRSRTRSRS 206
+ RR +D+ +++ + S +ERL + ++R SR RS S
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 126
Query: 207 RTRSRER 213
R+RSRER
Sbjct: 127 RSRSRER 133
Score = 48.9 bits (115), Expect = 2e-05
Identities = 40/108 (37%), Positives = 56/108 (51%), Gaps = 20/108 (18%)
Query: 107 KEEITKEEEREKKFSRRLNHSPPQSSSRYRE---NRSRD-ERKKDDRSRKRDYDRNPPRR 162
+E + RE+K SR + +S SR RE +RSR ERK+ RSR R
Sbjct: 131 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR--------- 181
Query: 163 DSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRS 210
+R R R R+ SRSR+RS S++R + ++ R +RS SRT S
Sbjct: 182 -------SRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 222
Score = 44.3 bits (103), Expect = 6e-04
Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 10/163 (6%)
Query: 106 KKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPR-RDS 164
++ + ++ RE+K SR + +S SR RE + R + RSR R R+ R R
Sbjct: 140 RERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSR 199
Query: 165 YRDRYNRRRGRSRSYSRSRSRSWSKERLRERDR--------DRSRTRSRSRTRSRERDLV 216
RDR +R + R +SRS SR+ S R R+ R R++ RE+++V
Sbjct: 200 SRDR-KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMV 258
Query: 217 KPKYDLDRTDPLENNYTPVSSVPSISSGHYPVPTLSSTITVIA 259
+ + + + ++ ++SG P ++ + A
Sbjct: 259 EKQKQQEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAA 301
Score = 36.6 bits (83), Expect = 0.12
Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 5/67 (7%)
Query: 156 DRNPPRRDSYRDRYN---RRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRE 212
++ P RD +++ R YSRSRSRS +ER R+ D + + RSRSR++
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRS--RERKRKSDNEGRKHRSRSRSKEGR 71
Query: 213 RDLVKPK 219
R K K
Sbjct: 72 RHESKDK 78
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 70.9 bits (172), Expect = 6e-12
Identities = 40/116 (34%), Positives = 60/116 (51%), Gaps = 2/116 (1%)
Query: 100 HQEKDIKKE-EITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKD-DRSRKRDYDR 157
H+E+D + + E +E ++E+ R+ + + R RE + + ERK+ DR R +D DR
Sbjct: 43 HRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDR 102
Query: 158 NPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRER 213
R NR+ GR R R R +ER R+R+R+R R R R R RER
Sbjct: 103 ERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRER 158
Score = 60.8 bits (146), Expect = 6e-09
Identities = 41/118 (34%), Positives = 55/118 (46%), Gaps = 7/118 (5%)
Query: 101 QEKDIKKE---EITKEEEREKKFSRRLNHSPPQSSSRYRE-NRSRDERKKDDRSRKRDYD 156
+E D KE E ++ ERE + R H + R+RE +R D K+ +R ++RD
Sbjct: 9 RETDRGKETERERDRQRERENQTERENRH---RQRDRHRERDRQTDREKERERQKERDRQ 65
Query: 157 RNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERD 214
R R R R R R R R K+R RER R+ R R R+R RERD
Sbjct: 66 RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERD 123
Score = 58.2 bits (139), Expect = 4e-08
Identities = 31/109 (28%), Positives = 52/109 (47%)
Query: 106 KKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSY 165
++ E +E +R K+ R + + + RENR R + +R R+ D ++ R+
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 166 RDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERD 214
+ R R R R R R +ER R+ DR+R + R R R R +R+
Sbjct: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111
Score = 56.2 bits (134), Expect = 1e-07
Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 1/110 (0%)
Query: 115 EREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRG 174
ER+++ R + R R+ ++ ++++R R+RD R R+ R++
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 175 RSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKYDLDR 224
R R R R ER RER R R R R R R ++RD + K + DR
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRER-KRETDR 110
Score = 53.1 bits (126), Expect = 1e-06
Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPP 160
+E+D ++E + ERE + +R H + + R R + + R R+R+ +R
Sbjct: 19 RERDRQRER-ENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETE 77
Query: 161 R-RDSYRDRYNRRR-GRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERD 214
R R+ R R +R+ R R R R R +R RER+R R R + R R+R+
Sbjct: 78 RQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRE 133
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/130 (26%), Positives = 68/130 (52%), Gaps = 11/130 (8%)
Query: 101 QEKDIKKE-EITKEEEREKKFSRRLNHSPPQSSSRYRE-----NRSRDERKKDDRSRKRD 154
+E++ ++E E +E +R+++ R+ + + R R+ NR R+ + +R ++ +
Sbjct: 68 RERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTE 127
Query: 155 YDRNPPR-RDSYRDR-YNRRRGRSRSYSRSRSRSWS--KERLRERDRDRSRTRSRSRTRS 210
+R+ R R R+R R+R R R R R R W+ +ER +ER ++R + R +
Sbjct: 128 RERDRERERQRQRERERQRQRERKRETDRERQR-WAEREERKKERKKERKKERKEKKKEE 186
Query: 211 RERDLVKPKY 220
+ R+ K K+
Sbjct: 187 KRREDKKRKW 196
>gi|116812577 LUC7-like 2 [Homo sapiens]
Length = 392
Score = 69.7 bits (169), Expect = 1e-11
Identities = 49/145 (33%), Positives = 71/145 (48%), Gaps = 9/145 (6%)
Query: 91 GSLKVEFFPHQEK--DIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDD 148
G L + F +EK ++K+ K+E+R ++ +R + + R +RS + K
Sbjct: 212 GKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRS 271
Query: 149 RSRK------RDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRT 202
RSR+ R R RR + R R R RSRS SRSRSRS + R RDR R R+
Sbjct: 272 RSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERS 331
Query: 203 RSR-SRTRSRERDLVKPKYDLDRTD 226
+ R S+ R R++DL D D
Sbjct: 332 KRRSSKERFRDQDLASCDRDRSSRD 356
Score = 41.6 bits (96), Expect = 0.004
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 100 HQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNP 159
H+ + + +E K R K +R H +SSSR R +RS + R R R+ +
Sbjct: 279 HRSRSMSRER--KRRTRSKSREKRHRHR-SRSSSRSR-SRSHQRSRHSSRDRSRERSKRR 334
Query: 160 PRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERD 214
++ +RD+ R RS SR RS + ++R + + RS R S ER+
Sbjct: 335 SSKERFRDQDLASCDRDRS-SRDRSPRDRDRKDKKRSYESANGRSEDRRSSEERE 388
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 69.7 bits (169), Expect = 1e-11
Identities = 58/201 (28%), Positives = 94/201 (46%), Gaps = 25/201 (12%)
Query: 33 AKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAV--------NTKSYLPP 84
A+ ++ LV++ K E+EL ++ F +E Q+ V ++ A +L
Sbjct: 155 AQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMG 214
Query: 85 PEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRD-E 143
+ +K +EK K+ E +ER KK + RE R ++ E
Sbjct: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKK------------EKQEREEREKERE 262
Query: 144 RKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSR----SWSKERLRERDRDR 199
R++++R RKR + ++ RDR R+R RSRS SR+ S S++ R R R+R
Sbjct: 263 REREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER 322
Query: 200 SRTRSRSRTRSRERDLVKPKY 220
R+RSR R RSR D + K+
Sbjct: 323 RRSRSRDRRRSRSHDRSERKH 343
Score = 68.9 bits (167), Expect = 2e-11
Identities = 44/122 (36%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 99 PHQEKDIKKEEITKEE---EREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDY 155
P +++ +KKE+ +EE ERE++ R + R +E ER+K RSR R
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 156 DRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDL 215
R RR S + R R R R SRSR R S+ R + RSR+R R R++SR+R
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS 360
Query: 216 VK 217
K
Sbjct: 361 YK 362
Score = 60.8 bits (146), Expect = 6e-09
Identities = 40/116 (34%), Positives = 62/116 (53%), Gaps = 10/116 (8%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDR--SRKRDYDRN 158
+E++ K+ +EEEREK+ +R + + +RSR + DR SR RD+ R+
Sbjct: 266 EERERKRRR--EEEEREKERAR------DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 159 PPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERD 214
R +RRR RS S + RS S++R R + RDR + RS++R RE+D
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQD 373
Score = 60.5 bits (145), Expect = 8e-09
Identities = 33/112 (29%), Positives = 52/112 (46%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPP 160
+E++ +++E ++ ER K+ R HS S R +R + +R R R DR
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS 333
Query: 161 RRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRE 212
R +R +R R R R S+SR R K R + RDR++ R R +
Sbjct: 334 RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
Score = 40.8 bits (94), Expect = 0.006
Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 5/106 (4%)
Query: 107 KEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYR 166
K ++E R + RR + S +S ++R +RSRD R+ R RK Y RD +
Sbjct: 315 KRSRSRERRRSRSRDRRRSRSHDRSERKHR-SRSRDRRRSKSRDRK-SYKHRSKSRDREQ 372
Query: 167 DRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRE 212
DR ++ + + S + +S K RE+ + + T S+ E
Sbjct: 373 DRKSKEKEKRGSDDK---KSSVKSGSREKQSEDTNTESKESDTKNE 415
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 69.7 bits (169), Expect = 1e-11
Identities = 58/201 (28%), Positives = 94/201 (46%), Gaps = 25/201 (12%)
Query: 33 AKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAV--------NTKSYLPP 84
A+ ++ LV++ K E+EL ++ F +E Q+ V ++ A +L
Sbjct: 155 AQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMG 214
Query: 85 PEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRD-E 143
+ +K +EK K+ E +ER KK + RE R ++ E
Sbjct: 215 KQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKK------------EKQEREEREKERE 262
Query: 144 RKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSR----SWSKERLRERDRDR 199
R++++R RKR + ++ RDR R+R RSRS SR+ S S++ R R R+R
Sbjct: 263 REREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRER 322
Query: 200 SRTRSRSRTRSRERDLVKPKY 220
R+RSR R RSR D + K+
Sbjct: 323 RRSRSRDRRRSRSHDRSERKH 343
Score = 68.9 bits (167), Expect = 2e-11
Identities = 44/122 (36%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 99 PHQEKDIKKEEITKEE---EREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDY 155
P +++ +KKE+ +EE ERE++ R + R +E ER+K RSR R
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 156 DRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDL 215
R RR S + R R R R SRSR R S+ R + RSR+R R R++SR+R
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKS 360
Query: 216 VK 217
K
Sbjct: 361 YK 362
Score = 60.8 bits (146), Expect = 6e-09
Identities = 40/116 (34%), Positives = 62/116 (53%), Gaps = 10/116 (8%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDR--SRKRDYDRN 158
+E++ K+ +EEEREK+ +R + + +RSR + DR SR RD+ R+
Sbjct: 266 EERERKRRR--EEEEREKERAR------DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 159 PPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERD 214
R +RRR RS S + RS S++R R + RDR + RS++R RE+D
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQD 373
Score = 60.5 bits (145), Expect = 8e-09
Identities = 33/112 (29%), Positives = 52/112 (46%)
Query: 101 QEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPP 160
+E++ +++E ++ ER K+ R HS S R +R + +R R R DR
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRS 333
Query: 161 RRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRE 212
R +R +R R R R S+SR R K R + RDR++ R R +
Sbjct: 334 RSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
Score = 40.8 bits (94), Expect = 0.006
Identities = 29/106 (27%), Positives = 49/106 (46%), Gaps = 5/106 (4%)
Query: 107 KEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYR 166
K ++E R + RR + S +S ++R +RSRD R+ R RK Y RD +
Sbjct: 315 KRSRSRERRRSRSRDRRRSRSHDRSERKHR-SRSRDRRRSKSRDRK-SYKHRSKSRDREQ 372
Query: 167 DRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRE 212
DR ++ + + S + +S K RE+ + + T S+ E
Sbjct: 373 DRKSKEKEKRGSDDK---KSSVKSGSREKQSEDTNTESKESDTKNE 415
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 69.3 bits (168), Expect = 2e-11
Identities = 127/516 (24%), Positives = 184/516 (35%), Gaps = 109/516 (21%)
Query: 41 KKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAVNTKSYLP---------PPEQPSSG 91
+K + E+ELK+ D+ ++ET K D+ +S P + PS
Sbjct: 182 EKTRKERELKSGHKDRSKSHRKRETPKSY-KTVDSPKRRSRSPHRKWSDSSKQDDSPSGA 240
Query: 92 SLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPP-------QSSSRYRENRSRDER 144
S ++ + ++ SRR + SPP QSS+R SR +R
Sbjct: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 145 KKDDRSRKRD--YDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRT 202
SR+R Y+R+ Y RRR S S+ RS S+ L R +SR+
Sbjct: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSK---RSLSRSPLPSRKSMKSRS 357
Query: 203 RS--------------RSRTRSRERDLVKPKYDLD---------------------RTDP 227
RS RS +RSR + + L+ + D
Sbjct: 358 RSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDG 417
Query: 228 LENNYTPV-------SSVPSISSG--HYPVPTL-----SSTITVIAPTHHGNNTTESWSE 273
E+ +PV SSV + SG +P S+ T + H N ++ S+
Sbjct: 418 KESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSD 477
Query: 274 FHEDQVDHNSYVRPPMPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPA 333
+ ++D NS K D K ++ ++ + P LP A
Sbjct: 478 TGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVT----PKETETSEKETPPPLPTIA 533
Query: 334 QPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPP----PPLPPLQP 389
PP PP P PPP PP+ P +P PLPPS P + P LPP
Sbjct: 534 SPP----PPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTH 589
Query: 390 SGMDAPPNSATSSVP--------TVVTTGIHH------QPPPAPPSLFTADTYDTDGYNP 435
S A + A S P VT I H P P PP L D D
Sbjct: 590 SKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMD------ 643
Query: 436 EAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPP 471
+P T S+P+ + + R L D+ LPP
Sbjct: 644 -SPKETLPSKPVKKEKEQRTRHLLT-----DLPLPP 673
Score = 36.6 bits (83), Expect = 0.12
Identities = 28/82 (34%), Positives = 33/82 (40%), Gaps = 22/82 (26%)
Query: 334 QPPVVEGPPPPGLPPPPPI----LTPPPVNLRPPV-------------PPPGPLP---PS 373
+PP GPPPP PPPPP+ L+ P L P V PPG LP +
Sbjct: 1256 RPPEPPGPPPP--PPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQA 1313
Query: 374 LPPVTGPPPPLPPLQPSGMDAP 395
L P+ P P D P
Sbjct: 1314 LRPMEYSTRPRPNRTYGNTDGP 1335
Score = 35.8 bits (81), Expect = 0.20
Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 21/130 (16%)
Query: 100 HQEKDIKKEEITKEEEREKKFSRRLNHSP--------PQSSSRYRENRSRDERKKDD--- 148
H+EK K+ E+ K +++ S R +P P+ SR + D K+DD
Sbjct: 180 HKEKTRKEREL-KSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPS 238
Query: 149 -RSRKRDYDRNPPR--RDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSR 205
S +DYD +P R S D Y + G S SR +S S +E +S TRS
Sbjct: 239 GASYGQDYDLSPSRSHTSSNYDSYKKSPG-----STSRRQSVSPP-YKEPSAYQSSTRSP 292
Query: 206 SRTRSRERDL 215
S R+R +
Sbjct: 293 SPYSRRQRSV 302
Score = 34.7 bits (78), Expect = 0.45
Identities = 25/81 (30%), Positives = 29/81 (35%), Gaps = 13/81 (16%)
Query: 340 GPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSA 399
GP P P P RPP PP P PPPP PPL + + P
Sbjct: 1237 GPQGPRRTPTMP--QEEAAEKRPPEPPGPP----------PPPPPPPLVEGDLSSAPQEL 1284
Query: 400 TSSVPTVVTTGIHHQPPPAPP 420
+V T + QP PP
Sbjct: 1285 NPAV-TAALLQLLSQPEAEPP 1304
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 69.3 bits (168), Expect = 2e-11
Identities = 127/516 (24%), Positives = 184/516 (35%), Gaps = 109/516 (21%)
Query: 41 KKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAVNTKSYLP---------PPEQPSSG 91
+K + E+ELK+ D+ ++ET K D+ +S P + PS
Sbjct: 182 EKTRKERELKSGHKDRSKSHRKRETPKSY-KTVDSPKRRSRSPHRKWSDSSKQDDSPSGA 240
Query: 92 SLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPP-------QSSSRYRENRSRDER 144
S ++ + ++ SRR + SPP QSS+R SR +R
Sbjct: 241 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR 300
Query: 145 KKDDRSRKRD--YDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRT 202
SR+R Y+R+ Y RRR S S+ RS S+ L R +SR+
Sbjct: 301 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSK---RSLSRSPLPSRKSMKSRS 357
Query: 203 RS--------------RSRTRSRERDLVKPKYDLD---------------------RTDP 227
RS RS +RSR + + L+ + D
Sbjct: 358 RSPAYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDG 417
Query: 228 LENNYTPV-------SSVPSISSG--HYPVPTL-----SSTITVIAPTHHGNNTTESWSE 273
E+ +PV SSV + SG +P S+ T + H N ++ S+
Sbjct: 418 KESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSD 477
Query: 274 FHEDQVDHNSYVRPPMPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPA 333
+ ++D NS K D K ++ ++ + P LP A
Sbjct: 478 TGKVKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVT----PKETETSEKETPPPLPTIA 533
Query: 334 QPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPP----PPLPPLQP 389
PP PP P PPP PP+ P +P PLPPS P + P LPP
Sbjct: 534 SPP----PPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTH 589
Query: 390 SGMDAPPNSATSSVP--------TVVTTGIHH------QPPPAPPSLFTADTYDTDGYNP 435
S A + A S P VT I H P P PP L D D
Sbjct: 590 SKTSAVSSQANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMD------ 643
Query: 436 EAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPP 471
+P T S+P+ + + R L D+ LPP
Sbjct: 644 -SPKETLPSKPVKKEKEQRTRHLLT-----DLPLPP 673
Score = 40.8 bits (94), Expect = 0.006
Identities = 31/90 (34%), Positives = 37/90 (41%), Gaps = 22/90 (24%)
Query: 326 PGMLPFPAQPPVVEGPPPPGLPPPPPI----LTPPPVNLRPPV-------------PPPG 368
P +LP +PP GPPPP PPPPP+ L+ P L P V PPG
Sbjct: 1257 PHILPPEKRPPEPPGPPPP--PPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPG 1314
Query: 369 PLP---PSLPPVTGPPPPLPPLQPSGMDAP 395
LP +L P+ P P D P
Sbjct: 1315 HLPHEHQALRPMEYSTRPRPNRTYGNTDGP 1344
Score = 37.7 bits (86), Expect = 0.053
Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 4/81 (4%)
Query: 340 GPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSA 399
GP P P P P + PP PP PP PPPP PPL + + P
Sbjct: 1237 GPQGPRRTPTMP--QEEAAACPPHILPPEKRPPE-PPGPPPPPPPPPLVEGDLSSAPQEL 1293
Query: 400 TSSVPTVVTTGIHHQPPPAPP 420
+V T + QP PP
Sbjct: 1294 NPAV-TAALLQLLSQPEAEPP 1313
Score = 35.8 bits (81), Expect = 0.20
Identities = 39/130 (30%), Positives = 57/130 (43%), Gaps = 21/130 (16%)
Query: 100 HQEKDIKKEEITKEEEREKKFSRRLNHSP--------PQSSSRYRENRSRDERKKDD--- 148
H+EK K+ E+ K +++ S R +P P+ SR + D K+DD
Sbjct: 180 HKEKTRKEREL-KSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPS 238
Query: 149 -RSRKRDYDRNPPR--RDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSR 205
S +DYD +P R S D Y + G S SR +S S +E +S TRS
Sbjct: 239 GASYGQDYDLSPSRSHTSSNYDSYKKSPG-----STSRRQSVSPP-YKEPSAYQSSTRSP 292
Query: 206 SRTRSRERDL 215
S R+R +
Sbjct: 293 SPYSRRQRSV 302
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 69.3 bits (168), Expect = 2e-11
Identities = 42/89 (47%), Positives = 46/89 (51%), Gaps = 13/89 (14%)
Query: 336 PVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPG-PLPPSLPPVTGPPPPLPPLQPSGMDA 394
P + PPPPG PP PP PPP PP P PG P+PP LPP PPPP PP P+
Sbjct: 677 PTLPLPPPPGFPPLPP---PPP----PPPPQPGFPMPPPLPP---PPPPPPPAHPAVTVP 726
Query: 395 PPNSATSSVPTVVTTGIHHQPPPAPPSLF 423
PP + P V I PP PP LF
Sbjct: 727 PP--PLPAPPGVPPPPILPPLPPFPPGLF 753
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/72 (43%), Positives = 35/72 (48%), Gaps = 11/72 (15%)
Query: 326 PGMLPFPAQPPVVEG-PPPPGLPPPPP--------ILTPPPVNLRPPVPPPGPLPPSLPP 376
P + P P PP G P PP LPPPPP + PPP PP PP P+ P LPP
Sbjct: 688 PPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPP 747
Query: 377 VTGPPPPLPPLQ 388
PP P +Q
Sbjct: 748 F--PPGLFPVMQ 757
Score = 43.9 bits (102), Expect = 7e-04
Identities = 86/399 (21%), Positives = 136/399 (34%), Gaps = 45/399 (11%)
Query: 112 KEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRD-SYRDRYN 170
+E+E+E + + + + E D+ DDR + D + + S +D +
Sbjct: 1034 EEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGD 1093
Query: 171 RRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLEN 230
+ S S++ + S E S + S + E ++V + + + E
Sbjct: 1094 SDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE---EEEEEEEE 1150
Query: 231 NYTPVSSVPSISSGHYPVPTLSSTITVIAPTHHGNNTTESW---SEFHEDQVDHNSYVRP 287
S+ S + + + AP E +E + + P
Sbjct: 1151 EMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEP 1210
Query: 288 PMPKKRCRDYD------EKGFCMRGDMCPFDHGSDPVVVEDVNLPGMLP--FPAQPPVVE 339
P+P D E G G M +P E P + P P VE
Sbjct: 1211 PLPVGVEEPADSREPPEEPGLSQEGAMLL---SPEPPAKEVEARPPLSPERAPEHDLEVE 1267
Query: 340 GPPPPGLPPP--PPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPL----PPLQPSGMD 393
PP LP P PP+ PPP RPP PPP P + PP PL PP P
Sbjct: 1268 PEPPMMLPLPLQPPL--PPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCG 1325
Query: 394 APPNS-ATSSVPTVV---------TTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNT 443
+ S +T +VP ++G+ P P S F+ Y +PS+++
Sbjct: 1326 SLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFS--------YPAPSPSLSSG 1377
Query: 444 SRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMR 482
P R + P SG + LP P + R
Sbjct: 1378 GLPRTPGRDFSFTPT-FSEPSGPLLLPVCPLPTGRRDER 1415
Score = 41.6 bits (96), Expect = 0.004
Identities = 42/145 (28%), Positives = 57/145 (39%), Gaps = 15/145 (10%)
Query: 333 AQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLP-PVTGPPPPLPPLQPSG 391
A P ++E P LP P P+ P LR P PLPP LP P+ PPP+
Sbjct: 1420 ASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRP 1479
Query: 392 MDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNTSRPMYRHR 451
+PP+ + P V PPA +L + G P+ P +T P R
Sbjct: 1480 RRSPPSMLSLDGPLV--------RPPAGAAL-GRELLLLPG-QPQTPVFPSTHDP----R 1525
Query: 452 VHAQRPNLIGLTSGDMDLPPREKPP 476
G+ + LPP+ PP
Sbjct: 1526 TVTLDFRNAGIPAPPPPLPPQPPPP 1550
Score = 39.7 bits (91), Expect = 0.014
Identities = 54/217 (24%), Positives = 77/217 (35%), Gaps = 60/217 (27%)
Query: 332 PAQPPVVEGPPPPG------------------LPPPPPILTPPPVNLRPPVPPPGPLPP- 372
P Q PV PPPP P PPP+ P+ P PPGP PP
Sbjct: 399 PYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPD 458
Query: 373 --------------SLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVV----TTGIHHQ 414
S P P P P+G + P +S S + ++ T + +
Sbjct: 459 TNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLR 518
Query: 415 PPPAPPSL---FTADTYDTDGYNPEAPSITNTSRPMYRHRV-HAQRPNLIGLTSGDMDLP 470
P + L + + + +P AP TN S+P +R + RP+ GL D+
Sbjct: 519 EPDSDTELQMEGSPISSSSSQLSPLAPFGTN-SQPGFRGPTPPSSRPSSTGLE----DIS 573
Query: 471 PREKPPNKSSMRIVVDSESRKRTIGSG-----EPGVP 502
P P + E + +G G EPG P
Sbjct: 574 PTPLPDS---------DEDEELDLGLGPRPPPEPGPP 601
Score = 38.9 bits (89), Expect = 0.024
Identities = 32/104 (30%), Positives = 40/104 (38%), Gaps = 39/104 (37%)
Query: 325 LPGMLPFP---AQPPVVEGPPPPGLPPPP------PILTPP------------PVNLRPP 363
LP +LP P PP+ P P PP P++ PP P + P
Sbjct: 1457 LPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTP 1516
Query: 364 VPP-----------------PGPLPPSLPPVTGPPPPLPPLQPS 390
V P P P PP LPP PPPP PP++P+
Sbjct: 1517 VFPSTHDPRTVTLDFRNAGIPAP-PPPLPPQPPPPPPPPPVEPT 1559
Score = 37.7 bits (86), Expect = 0.053
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 20/126 (15%)
Query: 315 SDPVVVED---VNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVP----PP 367
+ PV++E + LP LP P P V P PP+L P + PP+ P
Sbjct: 1420 ASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRP 1479
Query: 368 GPLPPSLPPVTGP--PPPLPP-------LQPSGMDAPPNSATSSVPTVV----TTGIHHQ 414
PPS+ + GP PP L P P +T TV GI
Sbjct: 1480 RRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAP 1539
Query: 415 PPPAPP 420
PPP PP
Sbjct: 1540 PPPLPP 1545
Score = 35.0 bits (79), Expect = 0.34
Identities = 25/73 (34%), Positives = 28/73 (38%), Gaps = 18/73 (24%)
Query: 328 MLPFPAQPPVVEGPPPP----------GLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPV 377
+LP Q PV P G+P PPP L PP PPP P PP + P
Sbjct: 1508 LLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPL--------PPQPPPPPPPPPVEPT 1559
Query: 378 TGPPPPLPPLQPS 390
P L PS
Sbjct: 1560 KLPFKELDNQWPS 1572
Score = 32.7 bits (73), Expect = 1.7
Identities = 22/103 (21%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 873 ESDREDLLPHFAQYGEIEDCQIDDSSLHAVITFKTRAEAEAAAVHGARFKGQDLKLAWNK 932
ES+ +D ++ E ++ D+ +++T K A + + + + F+ + +
Sbjct: 1073 ESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESS----SESS 1128
Query: 933 PVTNISAVETEEVEPDEEEFQEESLVDDSLLQDDDEE-EEDNE 974
P ++ E E +EEE +EE + ++S+ E+ E+D E
Sbjct: 1129 PSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGE 1171
Score = 32.0 bits (71), Expect = 2.9
Identities = 68/290 (23%), Positives = 89/290 (30%), Gaps = 69/290 (23%)
Query: 233 TPVSSVPSISSGHYPVPTL---SSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPM 289
TP S S SS P P+ H + T++++ HE HNS P +
Sbjct: 281 TPFSQDSSYSS-RQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNS---PAV 336
Query: 290 PKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQPPV--VEGPPPPGLP 347
+ G F SD LPF A GPP P
Sbjct: 337 T------------AVAGATAAFRGSSD------------LPFGAVGGTGGSSGPPFKAQP 372
Query: 348 PPPPIL--TPPPVNLRP---------PVPPP---GPLPPSLPPVTG-------------- 379
TPPP P P P P PP P T
Sbjct: 373 QDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAP 432
Query: 380 PPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQP----PPAPPSLFTADTYDTDGYNP 435
PPPLPP +P + P P + + +P P P T ++ P
Sbjct: 433 APPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGP 492
Query: 436 EAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMD--LPPREKPPNKSSMRI 483
E P + SR + QR L+ L D D L P + SS ++
Sbjct: 493 EKPHDSLDSR--IEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQL 540
Score = 30.4 bits (67), Expect = 8.5
Identities = 16/41 (39%), Positives = 18/41 (43%)
Query: 332 PAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPP 372
PA PP + PPP PPPP T P P +PP
Sbjct: 1537 PAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP 1577
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 68.9 bits (167), Expect = 2e-11
Identities = 41/102 (40%), Positives = 46/102 (45%), Gaps = 13/102 (12%)
Query: 332 PAQPPVVEGPPPP------GLPPPPPIL---TPPPVNLRPPVPPPGPLPPSLPPVTGPPP 382
P PP GPPPP PPPPP PPP R P P P PPS P V PPP
Sbjct: 278 PPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP 337
Query: 383 P----LPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPP 420
P PP P+ + P+ P+V+ G PPP PP
Sbjct: 338 PPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP 379
Score = 65.5 bits (158), Expect = 2e-10
Identities = 44/108 (40%), Positives = 48/108 (44%), Gaps = 23/108 (21%)
Query: 341 PPPP---GLPPPPPILTPPPVNLRPPVPP-----PGPLPPSLPPVTGPPPPLPPLQPSGM 392
PPPP G PPPP PPP N PP PP P PPS P PPPP PP +PS
Sbjct: 279 PPPPSRGGPPPPP----PPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPP-PPSRPSVA 333
Query: 393 --DAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEAP 438
PPN P + + PPP PPS+ G P AP
Sbjct: 334 VPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVL--------GVGPVAP 373
Score = 60.5 bits (145), Expect = 8e-09
Identities = 44/115 (38%), Positives = 46/115 (40%), Gaps = 33/115 (28%)
Query: 330 PFPAQPPVVEGPPPP-----GLPPPPP-----ILTPPPVNLRPPV------------PPP 367
P P PP GPPPP G PPPPP PPP RP V PPP
Sbjct: 288 PPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPP 347
Query: 368 GPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSL 422
LP S P +GPPPP P + G APP P PP PP L
Sbjct: 348 PALPSSAP--SGPPPPPPSVLGVGPVAPPPPPPPPPP---------PGPPPPPGL 391
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/92 (40%), Positives = 42/92 (45%), Gaps = 13/92 (14%)
Query: 330 PFPAQPPVVEGPPPP------GLPPPPPI-LTPPPVNLRPPVPPPGPLPPSLPPVTG--- 379
P P++ P PPPP +PPPPP + PPP P P GP PP P V G
Sbjct: 312 PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGP-PPPPPSVLGVGP 370
Query: 380 --PPPPLPPLQPSGMDAPPNSATSSVPTVVTT 409
PPPP PP P G PP + V TT
Sbjct: 371 VAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTT 402
Score = 52.4 bits (124), Expect = 2e-06
Identities = 35/80 (43%), Positives = 38/80 (47%), Gaps = 12/80 (15%)
Query: 326 PGMLPFPAQPPVVEGPPPPGLP------PPPPILTPPPVNLRPPVPPPGPLPPSLPPVTG 379
P + P P + PPPP LP PPPP PP V PV PP P PP PP G
Sbjct: 330 PSVAVPPPPPNRMYPPPPPALPSSAPSGPPPP---PPSVLGVGPVAPPPPPPP--PPPPG 384
Query: 380 PPPPLPPLQPSGMDAPPNSA 399
PPPP P L G P +A
Sbjct: 385 PPPP-PGLPSDGDHQVPTTA 403
Score = 47.8 bits (112), Expect = 5e-05
Identities = 36/118 (30%), Positives = 50/118 (42%), Gaps = 17/118 (14%)
Query: 362 PPVPPP---GPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPA 418
PP PPP GP PP PP PPP PP + G PP P+ T PPP+
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPP-PPARGRGAPPPP-------PSRAPTAAPPPPPPS 328
Query: 419 PPSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPP 476
PS+ Y P P++ +++ P+++G+ G + PP PP
Sbjct: 329 RPSVAVPPPPPNRMYPPPPPALPSSA----PSGPPPPPPSVLGV--GPVAPPPPPPPP 380
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 68.9 bits (167), Expect = 2e-11
Identities = 49/102 (48%), Positives = 60/102 (58%), Gaps = 8/102 (7%)
Query: 116 REKKFSRRLNHSPPQSSSRYRENRSRDERKK---DDRSRKRDYDRNPPRRDSYRDRYNRR 172
RE + R+ + S +S SR R D+R K D RSR RD DR RR+ R R ++R
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDR---RRERSRSR-DKR 58
Query: 173 RGRSRSYSR-SRSRSWSKERLRERDRDRSRTRSRSRTRSRER 213
R RSR R RSRS ++R RER R RSR R RSR+RSR R
Sbjct: 59 RSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGR 100
Score = 52.8 bits (125), Expect = 2e-06
Identities = 45/137 (32%), Positives = 64/137 (46%), Gaps = 17/137 (12%)
Query: 112 KEEEREKKFSRRLNHSPPQSSSRY---RENRSRDERKKDDRSRKRDY------DRNPPRR 162
+ R + SR + SP S+ R +RSRD ++ +RSR RD DR RR
Sbjct: 11 RSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRR 70
Query: 163 DSYRDR-YNRRRGRSRSYSRSRSRSWSKERL-------RERDRDRSRTRSRSRTRSRERD 214
R+R +R R RSRS R RSRS S+ R + + +R+RS+ +T E
Sbjct: 71 SRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESS 130
Query: 215 LVKPKYDLDRTDPLENN 231
K K D+ D E +
Sbjct: 131 KEKKKDKDDKEDEKEKD 147
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 8/72 (11%)
Query: 168 RYNRRRG--RSRSYSRSRSRSWSKERL------RERDRDRSRTRSRSRTRSRERDLVKPK 219
R+ R+R R RS SRSRSRS S +R R R RDR R R RSR+R + R + +
Sbjct: 6 RHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDR 65
Query: 220 YDLDRTDPLENN 231
L R+ E +
Sbjct: 66 KRLRRSRSRERD 77
Score = 40.4 bits (93), Expect = 0.008
Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 15/105 (14%)
Query: 104 DIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRD 163
D + ++ RE+ SR S + R R +RSR+ + +R R R DR RR
Sbjct: 37 DRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDR---RRS 93
Query: 164 SYRDRYNRRRG------------RSRSYSRSRSRSWSKERLRERD 196
R R R R RSRS ++ SKE+ +++D
Sbjct: 94 RSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKD 138
Score = 33.5 bits (75), Expect = 1.0
Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 22/63 (34%)
Query: 174 GRSRSY------------SRSRSRSWS----------KERLRERDRDRSRTRSRSRTRSR 211
GR + SRSRSRS S + R R+RDR R R+RSR + RSR
Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61
Query: 212 ERD 214
RD
Sbjct: 62 SRD 64
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 68.9 bits (167), Expect = 2e-11
Identities = 41/94 (43%), Positives = 44/94 (46%), Gaps = 12/94 (12%)
Query: 330 PFPAQPPVVEGP---PPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPP 386
P P PPV P PPP +PPP P PPP P PPP PP LPP PP PP
Sbjct: 480 PNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP---PPRLPPTHAVPPHPPP 536
Query: 387 LQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPP 420
G+ PP A+ P V G PPP PP
Sbjct: 537 ----GLGLPP--ASYPPPAVPPGGQPPVPPPIPP 564
Score = 61.2 bits (147), Expect = 4e-09
Identities = 41/83 (49%), Positives = 44/83 (53%), Gaps = 16/83 (19%)
Query: 326 PGMLPFPAQPPVVEGPPPP------GLPPPPPILTPPPVNLRPPVPPPG-PLPP-SLPPV 377
P P PA PP G PPP PPPPP L PP + PP PPPG LPP S PP
Sbjct: 491 PASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRL--PPTHAVPPHPPPGLGLPPASYPPP 548
Query: 378 TGPP---PPL-PPLQPSGMDAPP 396
PP PP+ PP+ P GM PP
Sbjct: 549 AVPPGGQPPVPPPIPPPGM--PP 569
Score = 50.1 bits (118), Expect = 1e-05
Identities = 39/109 (35%), Positives = 46/109 (42%), Gaps = 25/109 (22%)
Query: 330 PFPAQPPVVEGPPPPGLPP--PPPILTPPPVNLRPPVPPPGPLPPS-LPPVTGPPP--PL 384
P P + P +E PP LPP PPP PP PPGP+ + LP V PPP P
Sbjct: 350 PPPPKIPKIETTHPP-LPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPA 408
Query: 385 PPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGY 433
P QP PP + H+PPP PPS + T Y
Sbjct: 409 PVHQP-----PP--------------LPHRPPPPPPSSYMTGMSTTSSY 438
Score = 49.7 bits (117), Expect = 1e-05
Identities = 54/192 (28%), Positives = 69/192 (35%), Gaps = 54/192 (28%)
Query: 317 PVVVEDVNLPGM-LPFPAQPPVVEGPPP-PGLPPPPP---ILTPPPV-----------NL 360
P V+ +LP + +P PA P V PPP P PPPPP +T +L
Sbjct: 388 PGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSL 447
Query: 361 RPPVPPPGPLPPSLPPVTGPP-------------PPLPPLQPSGMDAPPNSATSSVPTVV 407
+ + GP +LPP GPP PP PP+ P PP + P
Sbjct: 448 QSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGY- 506
Query: 408 TTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDM 467
PP PP+ YNP P P H V P +GL
Sbjct: 507 --------PPPPPT-----------YNPNFPPPPPRLPP--THAVPPHPPPGLGLPPASY 545
Query: 468 D---LPPREKPP 476
+PP +PP
Sbjct: 546 PPPAVPPGGQPP 557
Score = 48.5 bits (114), Expect = 3e-05
Identities = 28/54 (51%), Positives = 30/54 (55%), Gaps = 5/54 (9%)
Query: 330 PFPAQPPVVEGPP--PPGLPPPPPILTPP--PVNLRPPVPPPGPLPPSLPPVTG 379
P P PP PP PPGL PP PP P +PPVPPP P PP +PPV G
Sbjct: 520 PPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIP-PPGMPPVGG 572
Score = 47.8 bits (112), Expect = 5e-05
Identities = 37/118 (31%), Positives = 43/118 (36%), Gaps = 19/118 (16%)
Query: 340 GPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSL-------PPVTGPPPPLPPLQPSGM 392
G PP PP + P V P PPP P PP+ PP G PPP P P+
Sbjct: 459 GALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFP 518
Query: 393 DAPPN-SATSSVPTVVTTGIHHQPPPA---PPSLFTADTYDTDGYNPEAPSITNTSRP 446
PP T +VP PPP PP+ + G P P I P
Sbjct: 519 PPPPRLPPTHAVPP--------HPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMP 568
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 68.9 bits (167), Expect = 2e-11
Identities = 36/92 (39%), Positives = 46/92 (50%), Gaps = 8/92 (8%)
Query: 316 DPVVVEDVNLPGMLPFPA---QPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPP 372
+P ++E+ P P P QPP PP P LP PPP++ P P + PPP PLPP
Sbjct: 1449 EPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS-----PPPPPLPP 1503
Query: 373 SLPPVTGPPPPLPPLQPSGMDAPPNSATSSVP 404
PP PPP PP + + APP + P
Sbjct: 1504 PPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Score = 65.5 bits (158), Expect = 2e-10
Identities = 50/152 (32%), Positives = 63/152 (41%), Gaps = 42/152 (27%)
Query: 321 EDVNLPGMLPFPAQPPVVEGPPPPGLP-------PPPPIL------TPPPV---NLRPPV 364
+D + P P V PP PGLP P PP+L TPPP +PP
Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPP 1473
Query: 365 PPPGPLP--PSLPPVTG------PPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPP 416
PPP P P PS PP+ PPPPLPP P M +PP PP
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP-----------------PPP 1516
Query: 417 PAPPSLFTADTYDTDGYNPEAPSITNTSRPMY 448
P + A + +PE P + +T RP++
Sbjct: 1517 PPAAAPLAAPPEEPAAPSPEDPELPDT-RPLH 1547
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/89 (35%), Positives = 37/89 (41%), Gaps = 11/89 (12%)
Query: 330 PFPAQPPVVEGPPP-----PGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPP--P 382
P P P + PPP P PPPPP+ PPP + P PPP PP+ P+ PP P
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP---PPAAAPLAAPPEEP 1530
Query: 383 PLP-PLQPSGMDAPPNSATSSVPTVVTTG 410
P P P D P T G
Sbjct: 1531 AAPSPEDPELPDTRPLHLAKKQETAAVCG 1559
Score = 52.4 bits (124), Expect = 2e-06
Identities = 34/96 (35%), Positives = 38/96 (39%), Gaps = 11/96 (11%)
Query: 336 PVVEGPPPPGLPPPPPILTPPPVNLRPPVP----------PPGPLPPSLPPVTGPPPPLP 385
P + GP P PP+ V PP+P P PL PP T PP P P
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
Query: 386 PLQPSGMDAPPNSATSSVPTVVT-TGIHHQPPPAPP 420
QP PP A S P +V T PPP PP
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP 1503
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/88 (30%), Positives = 34/88 (38%), Gaps = 9/88 (10%)
Query: 333 AQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGM 392
A PP EG P G PPP P P GP P GP P L P+
Sbjct: 965 AGPPEDEGDPKAGAGPPPG---------PPAYDPYGPYCPGRASGAGPETPGLGLDPNKP 1015
Query: 393 DAPPNSATSSVPTVVTTGIHHQPPPAPP 420
P++ + ++ +G H PP PP
Sbjct: 1016 PELPSTVNAEPLGLIQSGPHQAAPPPPP 1043
Score = 38.1 bits (87), Expect = 0.041
Identities = 26/62 (41%), Positives = 29/62 (46%), Gaps = 12/62 (19%)
Query: 336 PVVEGPPPPGL--------PPPPPILTPPPVNLRPPVPPPG-PLPPSLPPVTGPPPPLPP 386
P+V PPPP L P P P + V+L P G P PP PP PPPP P
Sbjct: 791 PLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPP---PPPPPMP 847
Query: 387 LQ 388
LQ
Sbjct: 848 LQ 849
Score = 38.1 bits (87), Expect = 0.041
Identities = 27/79 (34%), Positives = 31/79 (39%), Gaps = 12/79 (15%)
Query: 332 PAQPPVVEGPPPPGLPPPPPILTPPPVNLRP-PVPPPGPLPPSLPPVTGPPP-------- 382
PA PPPP PPPPP+ +LR + P P P P + PP
Sbjct: 826 PATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLG 885
Query: 383 ---PLPPLQPSGMDAPPNS 398
PLPP PPNS
Sbjct: 886 ALEPLPPAPGDTGVGPPNS 904
Score = 37.4 bits (85), Expect = 0.069
Identities = 36/111 (32%), Positives = 42/111 (37%), Gaps = 28/111 (25%)
Query: 348 PPPPILTPPPVNLRPPVPPPGPLP---PSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVP 404
PPPP PP P P L P LP V PPPP L PS + P+ + P
Sbjct: 764 PPPP---PPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPP--QLLPSVLSHAPSPS----P 814
Query: 405 TVVTTGIH----------HQPPPAPPS------LFTADTYDTDGYNPEAPS 439
+ G+H QPPP PP L + G P APS
Sbjct: 815 SASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPS 865
Score = 37.0 bits (84), Expect = 0.091
Identities = 30/88 (34%), Positives = 35/88 (39%), Gaps = 25/88 (28%)
Query: 332 PAQPPVVEG--PPPPGL------PPPPPILTPPPVNLRPPV----PPPGP---------L 370
P PP + P P GL P P +L PPP L P V P P P L
Sbjct: 765 PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL 824
Query: 371 PPS----LPPVTGPPPPLPPLQPSGMDA 394
P+ P PPPP PP P ++A
Sbjct: 825 EPATRDGAPQPPPPPPPPPPPMPLQLEA 852
Score = 32.7 bits (73), Expect = 1.7
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 10/50 (20%)
Query: 335 PPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPG--PLPPSLPPVTGPPP 382
PP+ + GL PP PP ++ P VP G P PP+ P V PPP
Sbjct: 1296 PPLYQA----GLTPP----LSPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337
Score = 32.3 bits (72), Expect = 2.2
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 5/47 (10%)
Query: 356 PPV---NLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSA 399
PP+ L PP+ PP +PPS+P P PP P+ PP+ A
Sbjct: 1296 PPLYQAGLTPPLSPPKSVPPSVP--ARGLQPQPPATPAVPHPPPSGA 1340
Score = 32.3 bits (72), Expect = 2.2
Identities = 52/220 (23%), Positives = 70/220 (31%), Gaps = 32/220 (14%)
Query: 361 RPPVPP----PGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPP 416
RPPVP P S + PPP P P P TS P T P
Sbjct: 1669 RPPVPVRRSGQAKNPVSAGGSSAPPPKAP--APPPKPETPEKTTSEKPPEQTPETAMPEP 1726
Query: 417 PAP--PSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREK 474
PAP PSL + E +T RP+ R TSG P R
Sbjct: 1727 PAPEKPSLLRPVEKE-----KEKEKVTRGERPLRGERA----------TSGRQTRPERSL 1771
Query: 475 PPNKSSMRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRT---NSPGFQKKVQFGNEN 531
+ + + + K EP +K W + N T PG +
Sbjct: 1772 ATGQPATSRLPKARPTK---VKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGA 1828
Query: 532 TKLELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPE 571
+ R VP L + E + + V + V+ DP+
Sbjct: 1829 PSEDERAVPGRLLKTRAMREMYRSY---VEMLVSTALDPD 1865
Score = 31.6 bits (70), Expect = 3.8
Identities = 35/131 (26%), Positives = 44/131 (33%), Gaps = 31/131 (23%)
Query: 327 GMLPFPAQPPVVEGPPPPGLPPPPPILTPPPV-NLRPPVPP------------------P 367
G PFP P + PP PP +L+P V +L+P P P
Sbjct: 158 GSRPFPV-PSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGP 216
Query: 368 GPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVT-----------TGIHHQPP 416
L P+ P P PP PP P + N SS +G PP
Sbjct: 217 AGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPP 276
Query: 417 PAPPSLFTADT 427
P +L DT
Sbjct: 277 PPERALPRQDT 287
Score = 31.6 bits (70), Expect = 3.8
Identities = 20/58 (34%), Positives = 22/58 (37%), Gaps = 4/58 (6%)
Query: 333 AQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPS 390
A+ PV G G PPP PP P PP P T P P P +PS
Sbjct: 1680 AKNPVSAG----GSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPS 1733
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 68.6 bits (166), Expect = 3e-11
Identities = 45/125 (36%), Positives = 54/125 (43%), Gaps = 17/125 (13%)
Query: 325 LPGMLPFPAQPPVVEGPPPP--GLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPP 382
+PG P P PP +GPPPP PP PP PP+ L PP PGP P G PP
Sbjct: 300 VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPP-------GAPP 352
Query: 383 PLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITN 442
P P + P+ P N S +PT + G PPP P YD Y P +
Sbjct: 353 PAPHVNPAFFPPPTN---SGMPTSDSRG----PPPTDP-YGRPPPYDRGDYGPPGREMDT 404
Query: 443 TSRPM 447
P+
Sbjct: 405 ARTPL 409
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/158 (32%), Positives = 58/158 (36%), Gaps = 31/158 (19%)
Query: 332 PAQPPVVEGPPPPGLPPPPPILTPPPVNLRPP-----------VPPPGPLPPSLPPVT-- 378
P PP GPPPPG PPP+ PP RPP PP GPLPP PP
Sbjct: 243 PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG 302
Query: 379 -GPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEA 437
GPPP PP Q G PP P + + PPP P G P A
Sbjct: 303 YGPPPGPPPPQ-QGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG-------PPPGAPPPA 354
Query: 438 PSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKP 475
P + P P G+ + D PP P
Sbjct: 355 PHVNPAFFP---------PPTNSGMPTSDSRGPPPTDP 383
Score = 65.5 bits (158), Expect = 2e-10
Identities = 47/116 (40%), Positives = 54/116 (46%), Gaps = 20/116 (17%)
Query: 330 PFPAQ--PPVVEGPPPPGLPPPPPILTP------PPVNLRPPVPPP-----GPLPPSLPP 376
P P Q PP + GPP G PPPP+L P PP+ PP PPP GP P PP
Sbjct: 253 PPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPP 312
Query: 377 VTGPPPPLPPL--QPSGMDAPPNSATSSVPTVVTTGIHHQPPPAP---PSLFTADT 427
GPPPP P +P G PP T + P + PPPAP P+ F T
Sbjct: 313 QQGPPPPPGPFPPRPPGPLGPP--LTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPT 366
Score = 56.2 bits (134), Expect = 1e-07
Identities = 46/110 (41%), Positives = 50/110 (45%), Gaps = 22/110 (20%)
Query: 326 PGMLPFPAQPPVVEGPPPPGLPPPP--PILTPPPVNLRPPVPP--PGPLPPSL---PPVT 378
PG +P + P GP PG PPPP TPP L PP PP PGP PP PP+
Sbjct: 208 PGAVPGGDRFP---GPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264
Query: 379 GPP-----PPLP---PLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPP 420
GPP PP P P QP G PP P G + PPP PP
Sbjct: 265 GPPNRGDRPPPPVLFPGQPFGQ--PPLGPLPPGPPPPVPG--YGPPPGPP 310
Score = 50.1 bits (118), Expect = 1e-05
Identities = 31/78 (39%), Positives = 43/78 (55%), Gaps = 11/78 (14%)
Query: 137 ENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERD 196
E++S + +RSR+RD+ R+ R RR +SRS R R + +ER RER+
Sbjct: 481 ESKSYGSGSRRERSRERDHSRS---------REKSRRHKSRS--RDRHDDYYRERSRERE 529
Query: 197 RDRSRTRSRSRTRSRERD 214
R R R R R R R RER+
Sbjct: 530 RHRDRDRDRDRERDRERE 547
Score = 40.8 bits (94), Expect = 0.006
Identities = 28/77 (36%), Positives = 33/77 (42%), Gaps = 13/77 (16%)
Query: 132 SSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYR-DRYNRRRGRSRSYSRSRSRSWSKE 190
S Y R+ ++ D SR R+ R R R D Y R R R R E
Sbjct: 482 SKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRER------------E 529
Query: 191 RLRERDRDRSRTRSRSR 207
R R+RDRDR R R R R
Sbjct: 530 RHRDRDRDRDRERDRER 546
Score = 37.7 bits (86), Expect = 0.053
Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 121 SRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSY 179
SR +HS + SR ++RSRD R R R+ +R+ RD RDR +R R R R Y
Sbjct: 494 SRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERH---RDRDRDR-DRERDREREY 548
Score = 37.4 bits (85), Expect = 0.069
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
Query: 131 SSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKE 190
S SR +R RD + ++SR R R+ R D Y +R R R R R R R +E
Sbjct: 487 SGSRRERSRERDHSRSREKSR-RHKSRSRDRHDDYYRERSRERERHRDRDRDRDRERDRE 545
Query: 191 R 191
R
Sbjct: 546 R 546
Score = 31.2 bits (69), Expect = 5.0
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 2/57 (3%)
Query: 112 KEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDR 168
++ R ++ SRR Y RSR+ + DR R RD +R+ R YR R
Sbjct: 497 RDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDRERD--REREYRHR 551
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 68.2 bits (165), Expect = 4e-11
Identities = 47/143 (32%), Positives = 73/143 (51%), Gaps = 16/143 (11%)
Query: 99 PHQEKDIK---KEEITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDY 155
P +E D + E+ +E ER + +SR + P+ R+R D+ RD+
Sbjct: 2099 PLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHR-----------DKDSSRDW 2147
Query: 156 DRNPPRRDSYRDRYNRR-RGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRSRERD 214
DRN R + RDR RG+ SR RSR+ +ER R RDRDRSR+R R R ++R+R+
Sbjct: 2148 DRNR-ERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRE 2206
Query: 215 LVKPKYDLDRTDPLENNYTPVSS 237
+ + D ++ + P +S
Sbjct: 2207 RGRDRKDRSKSKESARDPKPEAS 2229
Score = 46.2 bits (108), Expect = 1e-04
Identities = 35/106 (33%), Positives = 50/106 (47%), Gaps = 11/106 (10%)
Query: 96 EFFPHQEKDIKKE-----EITKEEEREKKFSRRLNHSPPQSSSRYRENRSRDERKKDDRS 150
E+ H++KD ++ E + +RE++ R + SR RE R RD R+ DRS
Sbjct: 2134 EWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRE-RERDRRRDRDRS 2192
Query: 151 RKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERD 196
R R+ DR D RDR R + RS S+ +R E R D
Sbjct: 2193 RSRERDR-----DKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
Score = 45.1 bits (105), Expect = 3e-04
Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 16/115 (13%)
Query: 131 SSSRYRENRSRDERKKDDRSRKRD-YDRNPPRRD---------SYRDRYNRRRGRSRSYS 180
+S+ +RE + + R + R+R+ +D P + + DR R R R R++S
Sbjct: 2066 ASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDR-RRERERGRNWS 2124
Query: 181 RSRS----RSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLENN 231
R R R W + R ++ RD R R RS R RER+ + K + DR+ N
Sbjct: 2125 RERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGK-EWDRSRERSRN 2178
Score = 34.7 bits (78), Expect = 0.45
Identities = 15/46 (32%), Positives = 20/46 (43%)
Query: 326 PGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLP 371
P P + V PP PPPPP+ PP + + + P P P
Sbjct: 1241 PSKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSP 1286
Score = 33.9 bits (76), Expect = 0.77
Identities = 24/72 (33%), Positives = 29/72 (40%), Gaps = 1/72 (1%)
Query: 332 PAQPPVVEGPPPPGLPPPPPILTPPP-VNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPS 390
PA P V P P P+ + V+ PP PP P P PPV L P PS
Sbjct: 1226 PAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKVLSSLKPAAPS 1285
Query: 391 GMDAPPNSATSS 402
A +A +S
Sbjct: 1286 PATAATTAAAAS 1297
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 67.4 bits (163), Expect = 6e-11
Identities = 39/92 (42%), Positives = 46/92 (50%), Gaps = 16/92 (17%)
Query: 339 EGPPPPGLPPP---------PPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQP 389
+ PPPP P P PP PPP + PPVPPPG LPP +PP PPPP+PP
Sbjct: 213 DAPPPPSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAM-PPPPMPP--G 269
Query: 390 SGMDAPPNSATSSVPTVVTTGI-HHQPPPAPP 420
+ PP++ T P G H P P PP
Sbjct: 270 AAGHGPPSAGT---PGAGHPGHGHSHPHPFPP 298
Score = 55.1 bits (131), Expect = 3e-07
Identities = 35/94 (37%), Positives = 41/94 (43%), Gaps = 18/94 (19%)
Query: 333 AQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPP-------PGPLPPSLPPVTGPPPPLP 385
A PP G PPP PP P PPP+ + P PP PGP+PP + GPPP +P
Sbjct: 324 AGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPH--GMRGPPPLMP 381
Query: 386 PLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAP 419
P +G PP P PPP P
Sbjct: 382 PHGYTGPPRPPPYGYQRGPL---------PPPRP 406
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/83 (43%), Positives = 38/83 (45%), Gaps = 23/83 (27%)
Query: 326 PGMLPFPAQPPV---VEGPP---PPGLPPP--------PPILTPPPVNLRPPVPPP---- 367
PGM P P PP+ GPP P G P P PP L PP PP PPP
Sbjct: 339 PGM-PHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQ 397
Query: 368 -GPLPPSLPPVTGPPPPLPPLQP 389
GPLPP P P PP+PP P
Sbjct: 398 RGPLPPPRPT---PRPPVPPRGP 417
Score = 47.0 bits (110), Expect = 9e-05
Identities = 30/81 (37%), Positives = 35/81 (43%), Gaps = 13/81 (16%)
Query: 340 GPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSA 399
GPP G PPP PP + P PPP +PP PP P P+ P GM PP
Sbjct: 325 GPPGSGGQPPPR----PPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPP--- 377
Query: 400 TSSVPTVVTTGIHHQPPPAPP 420
P + G + PP PP
Sbjct: 378 ----PLMPPHG--YTGPPRPP 392
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/59 (44%), Positives = 27/59 (45%), Gaps = 13/59 (22%)
Query: 330 PFPAQPPVVEGPPP-------PGLPPPPPI------LTPPPVNLRPPVPPPGPLPPSLP 375
P P P + GPPP G P PPP L PP RPPVPP GPL LP
Sbjct: 365 PGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGPLP 423
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 67.0 bits (162), Expect = 8e-11
Identities = 46/123 (37%), Positives = 54/123 (43%), Gaps = 12/123 (9%)
Query: 310 PFDHGSDPVVVEDVNLPGMLPFP-AQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPG 368
PF + P V P P A PP+ P PP PP P TPPP P PP
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735
Query: 369 PLPPSLP------PVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPP-APPS 421
+PPS P P PPP +PPL + APP S P + +PPP APP+
Sbjct: 736 QVPPSPPASPPMSPSATPPPRVPPL----LAAPPLQVPPSPPASLPMSPLAKPPPQAPPA 791
Query: 422 LFT 424
L T
Sbjct: 792 LAT 794
Score = 60.5 bits (145), Expect = 8e-09
Identities = 41/105 (39%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 326 PGMLPF--PAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPP 383
P PF PA PPV PP PP L PP+ + P P P+ PS P PPP
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPS--LAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Query: 384 L--PPLQ--PSGMDAPPNSATSSVPTVVTTGIHHQP---PPAPPS 421
L PPLQ PS +PP S +++ P V + P PP+PP+
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
Score = 58.9 bits (141), Expect = 2e-08
Identities = 44/143 (30%), Positives = 56/143 (39%), Gaps = 21/143 (14%)
Query: 309 CPFDHGSDPVVVEDVNLPGML--PFPAQPPVVEGPPPPGLPPPP--PILTPPPVNLRPPV 364
CP P+ P + P P PP + PP GLP PP P+ TPPP
Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP------- 619
Query: 365 PPPGPLPPSLPPVTGP--PPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSL 422
P +LPP+ P PP PPL P A P+ + V PPP+PP
Sbjct: 620 --QAPPXLALPPLQAPPSPPASPPLSPL---ATPSPQAPNALAVHLLQAPFSPPPSPP-- 672
Query: 423 FTADTYDTDGYNPEAPSITNTSR 445
+ P +PS T S+
Sbjct: 673 -VQAPFSPPASPPVSPSATPPSQ 694
Score = 58.2 bits (139), Expect = 4e-08
Identities = 45/130 (34%), Positives = 56/130 (43%), Gaps = 26/130 (20%)
Query: 324 NLPGMLPFPAQP-------PVVEGPPPPG----LPPPPPILTPPPVNLRPPVPPPGPLPP 372
NLP + P P Q P +E PP P PP P+ TPPP PP PP
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596
Query: 373 SL--PPVTG-PPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYD 429
+L PP+ G P PPL PL APP A + Q PP+PP+
Sbjct: 597 ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPL----------QAPPSPPASPPLSPLA 646
Query: 430 TDGYNPEAPS 439
T +P+AP+
Sbjct: 647 TP--SPQAPN 654
Score = 57.4 bits (137), Expect = 6e-08
Identities = 42/137 (30%), Positives = 54/137 (39%), Gaps = 27/137 (19%)
Query: 332 PAQPPVVEGPPPPG-LPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPS 390
P PP P P LPP PP+ TP P+ PP PPSL + PP P P
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPL-----APPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 391 GMDAPPNSATSSVPTVVTTGIHH-------QPPPAP--------------PSLFTADTYD 429
M PP A S+ T+ + H Q PP+P P+L ++
Sbjct: 371 SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430
Query: 430 TDGYNPEAPSITNTSRP 446
T S+T+ SRP
Sbjct: 431 TMSPRQTQASLTSPSRP 447
Score = 55.8 bits (133), Expect = 2e-07
Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 19/149 (12%)
Query: 315 SDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPP-----------PPILTPPPVNLRPP 363
+ P + P P P P ++ PP P PP PP+L PP+ + P
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771
Query: 364 VPPPGPLPPSLPPVTGPPPPL--PPLQPSGMDAPPNSATSSVPTVVTTGIHHQ----PPP 417
P P+ P P PP L PPLQ + +PP S P + + PPP
Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQ--ALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 418 APPSLFTADTYDTDGYNPEAPSITNTSRP 446
P + A P +P++ RP
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRP 858
Score = 53.1 bits (126), Expect = 1e-06
Identities = 32/81 (39%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 343 PPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPL-QPSGMDAPPNSATS 401
PP L PP LT PP+ P + PP PL + P+T P PP P + APP+ T+
Sbjct: 520 PPSLQTPPASLTTPPLENLPSLAPP-PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578
Query: 402 SVPTVVTTGIHHQPPPAPPSL 422
P + I PP APP+L
Sbjct: 579 P-PPETPSSIATPPPQAPPAL 598
Score = 52.8 bits (125), Expect = 2e-06
Identities = 53/179 (29%), Positives = 63/179 (35%), Gaps = 30/179 (16%)
Query: 326 PGMLPFPAQPPVVEGPPPPGLP----PPPPILTPPPVNLRPPVP-PPGPL---------- 370
P + P PP + PP LP PP P +PP L P P P L
Sbjct: 609 PPLSPLATPPP--QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 371 PPSLPPVTGP--PPPLPPLQPS---------GMDAPPNSATSSVPTVVTTGIHHQPPPAP 419
PP PPV P PP PP+ PS + APP S P PPP
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726
Query: 420 PSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLP--PREKPP 476
P A P +P ++ ++ P R P L S LP P KPP
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Score = 51.2 bits (121), Expect = 5e-06
Identities = 50/190 (26%), Positives = 62/190 (32%), Gaps = 45/190 (23%)
Query: 326 PGMLPFPAQPPVVEGPPPPGLPPPPPILTP----------------------PPVN---- 359
P P A PP+ P PP PP P+ TP PPV
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678
Query: 360 ------LRPPVPPPGPLPPSL--PPVTGPP-----PPL------PPLQPSGMDAPPNSAT 400
+ P PP PPSL PP+ PP PP+ PP P + APP
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738
Query: 401 SSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLI 460
S P PPP P L A P + ++ ++P + P L
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798
Query: 461 GLTSGDMDLP 470
L S P
Sbjct: 799 ALPSPPASFP 808
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/159 (27%), Positives = 58/159 (36%), Gaps = 29/159 (18%)
Query: 335 PPVVEGPPP----PGLPPPP------PILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPL 384
PP PP P L PPP P+ TP P P P PPS P+T PPP
Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS--PLTTPPPET 583
Query: 385 -------PPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEA 437
PP P + +PP +P+ + + PP APP L P +
Sbjct: 584 PSSIATPPPQAPPALASPP---LQGLPSPPLSPLATPPPQAPPXL-ALPPLQAPPSPPAS 639
Query: 438 PSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPP 476
P ++ + P Q PN + + P PP
Sbjct: 640 PPLSPLATP------SPQAPNALAVHLLQAPFSPPPSPP 672
Score = 46.2 bits (108), Expect = 1e-04
Identities = 49/171 (28%), Positives = 60/171 (35%), Gaps = 39/171 (22%)
Query: 310 PFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPP------------ 357
P S P+ P + P A PP+ P PP P P+ PPP
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798
Query: 358 VNLRPPVPPPG-------------PL---PPSLPPVTGPP----PPLPPLQPSGMDAP-- 395
PP PG PL PP PPV P PP PP P+ + AP
Sbjct: 799 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT-LQAPRR 857
Query: 396 ---PNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNT 443
P TS +T + PPP PPS + T + S T+T
Sbjct: 858 PPTPGPDTSVSGPRLTLALAPGPPP-PPSRSPSSTLSGPDLAGHSSSATST 907
Score = 42.4 bits (98), Expect = 0.002
Identities = 46/163 (28%), Positives = 59/163 (36%), Gaps = 30/163 (18%)
Query: 313 HGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRP-PVPPPGPLP 371
H S P + L + P PP + P G P+ TP P + PVPPP
Sbjct: 268 HPSQP---KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAA 324
Query: 372 PSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTD 431
LP P PPL P APP+ P APPSL T +
Sbjct: 325 TPLPATLPPSPPLATPLPL---APPS------------------PSAPPSLQTLPSPPAT 363
Query: 432 GYNPEAPSITN---TSRPMYRHRVHAQRPNLIGLTSGDMDLPP 471
+ PS+T + P + Q P+ LTS + PP
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIPPIQVPH--SLTSPSLQAPP 404
Score = 37.4 bits (85), Expect = 0.069
Identities = 48/178 (26%), Positives = 59/178 (33%), Gaps = 37/178 (20%)
Query: 325 LPGMLPFPAQPPVVEGPPPPGLPPPPPI----------------------LTPPPVNLRP 362
L L PA PP+ P P P+ L PP+ +
Sbjct: 457 LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS 516
Query: 363 PVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAP-PS 421
+ PP P T P LP L APP T+S P T H + PP P P
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSL------APPPLQTASAP---LTTPHLETPPCPAPC 567
Query: 422 LFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTS---GDMDLPPREKPP 476
A PE PS T P + + P L GL S + PP + PP
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALAS--PPLQGLPSPPLSPLATPPPQAPP 623
Score = 35.0 bits (79), Expect = 0.34
Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 23/95 (24%)
Query: 333 AQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLP-------------PSLPPVTG 379
A+ P + P PPG P PPP +TP + + G P P P G
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 380 P----------PPPLPPLQPSGMDAPPNSATSSVP 404
P P PP G APP TS P
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP 113
Score = 31.6 bits (70), Expect = 3.8
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 28/138 (20%)
Query: 348 PPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSS----- 402
P P TPP PP+ P LP S P T P + PL S + P A SS
Sbjct: 444 PSRPASTPPD---SPPLQAPLSLPASPPLQTSLSPAVSPLS-SPLTIHPLQALSSLASHS 499
Query: 403 ----VPTVVTTGIHHQPPPAPPSLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPN 458
+ +++ + Q APPSL + P + T+ P+ + + P
Sbjct: 500 PQAPLSSLIMPPLETQSSLAPPSL-------------QTPPASLTTPPL--ENLPSLAPP 544
Query: 459 LIGLTSGDMDLPPREKPP 476
+ S + P E PP
Sbjct: 545 PLQTASAPLTTPHLETPP 562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,803,319
Number of Sequences: 37866
Number of extensions: 3072926
Number of successful extensions: 72759
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1079
Number of HSP's successfully gapped in prelim test: 1598
Number of HSP's that attempted gapping in prelim test: 21739
Number of HSP's gapped (non-prelim): 21795
length of query: 980
length of database: 18,247,518
effective HSP length: 112
effective length of query: 868
effective length of database: 14,006,526
effective search space: 12157664568
effective search space used: 12157664568
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.