Search of human proteins with 31559829

Search of human proteins with 31559829

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31559829 keratin 25 [Homo sapiens]
         (450 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31559829 keratin 25 [Homo sapiens]                                 889   0.0  
gi|153945736 keratin 27 [Homo sapiens]                                717   0.0  
gi|114431246 keratin 25D [Homo sapiens]                               658   0.0  
gi|31559815 keratin 26 [Homo sapiens]                                 610   e-174
gi|192807292 keratin 24 [Homo sapiens]                                452   e-127
gi|195972866 keratin 10 [Homo sapiens]                                450   e-126
gi|4557699 keratin 12 [Homo sapiens]                                  420   e-117
gi|24430192 keratin 16 [Homo sapiens]                                 409   e-114
gi|15431310 keratin 14 [Homo sapiens]                                 403   e-112
gi|24430190 keratin 15 [Homo sapiens]                                 401   e-112
gi|131412228 keratin 13 isoform b [Homo sapiens]                      390   e-108
gi|131412225 keratin 13 isoform a [Homo sapiens]                      390   e-108
gi|4557701 keratin 17 [Homo sapiens]                                  385   e-107
gi|24234699 keratin 19 [Homo sapiens]                                 369   e-102
gi|55956899 keratin 9 [Homo sapiens]                                  339   3e-93
gi|4504927 keratin 36 [Homo sapiens]                                  328   6e-90
gi|94538345 keratin 35 [Homo sapiens]                                 308   8e-84
gi|27894337 keratin 20 [Homo sapiens]                                 304   9e-83
gi|116488398 keratin 32 [Homo sapiens]                                297   1e-80
gi|14917117 keratin 33A [Homo sapiens]                                291   6e-79
gi|14917115 keratin 31 [Homo sapiens]                                 291   8e-79
gi|10337581 type I hair keratin 3B [Homo sapiens]                     290   2e-78
gi|14917119 keratin 34 [Homo sapiens]                                 274   1e-73
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  273   2e-73
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  271   1e-72
gi|40354195 keratin 18 [Homo sapiens]                                 270   2e-72
gi|4557888 keratin 18 [Homo sapiens]                                  270   2e-72
gi|27894339 keratin 23 [Homo sapiens]                                 270   2e-72
gi|55770882 keratin 37 [Homo sapiens]                                 249   5e-66
gi|15431318 keratin 38 [Homo sapiens]                                 246   4e-65

>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  889 bits (2298), Expect = 0.0
 Identities = 450/450 (100%), Positives = 450/450 (100%)

Query: 1   MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG 60
           MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG
Sbjct: 1   MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG 60

Query: 61  GNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGP 120
           GNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGP
Sbjct: 61  GNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGP 120

Query: 121 GSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQ 180
           GSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQ
Sbjct: 121 GSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQ 180

Query: 181 SVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEM 240
           SVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEM
Sbjct: 181 SVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEM 240

Query: 241 NAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELT 300
           NAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELT
Sbjct: 241 NAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELT 300

Query: 301 EMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETE 360
           EMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETE
Sbjct: 301 EMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETE 360

Query: 361 GQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAI 420
           GQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAI
Sbjct: 361 GQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAI 420

Query: 421 VVKKVLEEVDQRSKILTTRLHSLEEKSQSN 450
           VVKKVLEEVDQRSKILTTRLHSLEEKSQSN
Sbjct: 421 VVKKVLEEVDQRSKILTTRLHSLEEKSQSN 450


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  717 bits (1852), Expect = 0.0
 Identities = 366/452 (80%), Positives = 397/452 (87%), Gaps = 11/452 (2%)

Query: 1   MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG 60
           MS+R SS SRR      TGS+RL  GG  FG GN+CG+ GIGSGFS AFGGSSS G  GG
Sbjct: 1   MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGG 60

Query: 61  G-----NPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWY 115
           G       CA FT NE GLLSGNEKVTMQNLNDRLASYL++V ALEEANADLEQKIKGWY
Sbjct: 61  GLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWY 120

Query: 116 EKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENE 175
           EKFGPGSCRGLDHDYSRYFPIID+LKNQII++TTSNA+ VLQ DNARLTADDFRLK+ENE
Sbjct: 121 EKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENE 180

Query: 176 LALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGN 235
           LALHQSVEAD+NGLRRVLDE+TLCRTDLEIQ ETLSEE+ YLKKNH+EEM+ LQCAAGGN
Sbjct: 181 LALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGN 240

Query: 236 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSA 295
           VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQIS+D GATTSA
Sbjct: 241 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSA 300

Query: 296 RNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 355
           RNEL EMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV
Sbjct: 301 RNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 360

Query: 356 RTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKD 415
           RTETEGQKLEYEQLLDIK+HLEKEIETYCLLI G+DG+C      SK  G G  G+Q KD
Sbjct: 361 RTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGEDGSC------SKSKGYGGPGNQTKD 414

Query: 416 PAKAIVVKKVLEEVDQRSKILTTRLHSLEEKS 447
            +K  +VK V+EE+D R K+L++R+H++EEKS
Sbjct: 415 SSKTTIVKTVVEEIDPRGKVLSSRVHTVEEKS 446


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  658 bits (1697), Expect = 0.0
 Identities = 336/454 (74%), Positives = 381/454 (83%), Gaps = 11/454 (2%)

Query: 1   MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGG---SSSGGN 57
           MSL+ S+ SR  C R   GS+R   GG  F   ++CG S  GS FS A GG   S  GG+
Sbjct: 1   MSLQFSNGSRHVCLRSGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGS 60

Query: 58  TGGGN----PCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKG 113
             GG      C GF  +E GLLSGNEKVTMQNLNDRLASYLD+V ALEEANA+LE+KIKG
Sbjct: 61  HAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKG 120

Query: 114 WYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYE 173
           WYEK+GPGSCRGLDHDYSRY   I+DLKN+II+STT+NAN +LQIDNARL ADDFRLKYE
Sbjct: 121 WYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYE 180

Query: 174 NELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAG 233
           NEL LHQ+VEAD+NGLRRVLDE+TLCRTD E+QYE+LSEEMTYLKKNH+EEM+ LQCAAG
Sbjct: 181 NELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAG 240

Query: 234 GNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATT 293
           GNVNVEMNAAPGVDL VLLNNMRAEYEALAEQNR+DAEAWFNEKSASLQQQIS D GA T
Sbjct: 241 GNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAAT 300

Query: 294 SARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLH 353
            AR++LTEM+RTLQTLEI+LQSL+ATKHSLECSLTETESNYC QLAQIQAQIGALEEQLH
Sbjct: 301 FARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLH 360

Query: 354 QVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQV 413
           QVRTETEGQKLEYE LLD+K+HLEKEIETYC LI GD  +C     KSK +GSG+ G+  
Sbjct: 361 QVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCS----KSKGFGSGSPGNSS 416

Query: 414 KDPAKAIVVKKVLEEVDQRSKILTTRLHSLEEKS 447
           KD +K  +VK V+EE+DQR K+L++R+HS+EEK+
Sbjct: 417 KDLSKTTLVKTVVEELDQRGKVLSSRIHSIEEKT 450


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  610 bits (1572), Expect = e-174
 Identities = 323/453 (71%), Positives = 359/453 (79%), Gaps = 8/453 (1%)

Query: 1   MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGG---N 57
           MS RLS  SRR C R  TGS RL GGGT F  GN C  SG  S FS    G SSGG   N
Sbjct: 1   MSFRLSGGSRRICSR--TGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCN 58

Query: 58  TGGG---NPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGW 114
           +GGG     CAGF  NE  LLSGNEKVTMQNLNDRLASYLD VHALEEANADLEQKIKG 
Sbjct: 59  SGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGR 118

Query: 115 YEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYEN 174
           YEK  PGS R  DHDYSRYF +I+DLK QI ++T  NA+ VLQ DNARLTADDFRLKYEN
Sbjct: 119 YEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYEN 178

Query: 175 ELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGG 234
           ELALH SVEAD +GLRRVLDE+TLC TDLEIQ ETLSEE+TYLKK+H+EEM+VLQ  AGG
Sbjct: 179 ELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGG 238

Query: 235 NVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTS 294
           NVNVEMNA PGVDLTVLLNNMRAEYE LAEQNR+DAEAWFNE+SA+LQQQIS+  GA T+
Sbjct: 239 NVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATA 298

Query: 295 ARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQ 354
           ARNELTE+KR LQTLEIELQSL+A KHS ECSL ETE NYC QL QIQ QIG +EEQL Q
Sbjct: 299 ARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQ 358

Query: 355 VRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVK 414
           +RTETEGQKLEYEQLLD+K+ LEKEI+ YC L+ G++   KS  YKSK Y   N G+Q K
Sbjct: 359 IRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAK 418

Query: 415 DPAKAIVVKKVLEEVDQRSKILTTRLHSLEEKS 447
           D  +  +VK V+EE+DQ   +L+ R+HS+EEKS
Sbjct: 419 DSTEETIVKTVVEELDQIGNLLSLRVHSVEEKS 451


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  452 bits (1163), Expect = e-127
 Identities = 253/450 (56%), Positives = 322/450 (71%), Gaps = 31/450 (6%)

Query: 18  TGSLRLYGGGTSFGTGNSCGISGI--GSGF--SSAFGGSSSGG--NTGGGNPCAGFTVNE 71
           +GS   +GGG+SFG     G+SG   GSGF  SS F   ++GG  + GGG    G  V +
Sbjct: 81  SGSGTGFGGGSSFG-----GVSGFGRGSGFCGSSRFSSGATGGFYSYGGG---MGGGVGD 132

Query: 72  RGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGS-CRGLDHDY 130
            GL SG EK TMQNLNDRLA+YLD V ALEEAN DLE KIK WY+K+GPGS   G   DY
Sbjct: 133 GGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDY 192

Query: 131 SRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLR 190
           S+Y+ II+DL+NQIIA+T  NA  +L IDNARL ADDFRLKYENEL L QSVEAD+NGLR
Sbjct: 193 SKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLR 252

Query: 191 RVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTV 250
           +VLD++T+ R+DLE+Q E+ +EE+ YL+KNH+EEM+ +Q ++GG V VEMNAAPG DLT 
Sbjct: 253 KVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTK 312

Query: 251 LLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLE 310
           LLN+MRA+YE LAEQNRR+AE  FN++SASLQ QIS D GA TSA+NE+TE+KRTLQ LE
Sbjct: 313 LLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALE 372

Query: 311 IELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLL 370
           IELQS LA K SLE +L +TE+ Y AQL++IQ QI ALEE++ Q+  ET+ Q  EY+QLL
Sbjct: 373 IELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLL 432

Query: 371 DIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGS---------------QVKD 415
           DIK  LE EIETY  L+ G+ G      +  ++ GS N+GS               Q +D
Sbjct: 433 DIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRD 492

Query: 416 PAKAIVVKKVLEEVDQRSKILTTRLHSLEE 445
            +K  V K ++EE+    K++++++ S+ E
Sbjct: 493 SSKTRVTKTIVEELVD-GKVVSSQVSSISE 521


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  450 bits (1157), Expect = e-126
 Identities = 247/412 (59%), Positives = 293/412 (71%), Gaps = 21/412 (5%)

Query: 19  GSLRLYGGGTSFGTGN---SCGISGIGSGFSSAFGGSSSGGNT-----------GGGNPC 64
           GS   YGG   FG G+   S G S  G  +  +FGG S GG +           GGG   
Sbjct: 69  GSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFG 128

Query: 65  AGF---TVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPG 121
            GF      + GLLSGNEKVTMQNLNDRLASYLD V ALEE+N +LE KIK WYEK G  
Sbjct: 129 GGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHG-N 187

Query: 122 SCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQS 181
           S +G   DYS+Y+  IDDLKNQI+  TT NAN +LQIDNARL ADDFRLKYENE+AL QS
Sbjct: 188 SHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQS 247

Query: 182 VEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMN 241
           VEAD+NGLRRVLDE+TL + DLE+Q E+L+EE+ YLKKNH+EEM+ L+  + G+VNVEMN
Sbjct: 248 VEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMN 307

Query: 242 AAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTE 301
           AAPGVDLT LLNNMR++YE LAEQNR+DAEAWFNEKS  L  +I  ++   +S ++E+TE
Sbjct: 308 AAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITE 367

Query: 302 MKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEG 361
           ++R +Q LEIELQS LA K SLE SL ETE  YC QL+QIQAQI ALEEQL Q+R ETE 
Sbjct: 368 LRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETEC 427

Query: 362 QKLEYEQLLDIKLHLEKEIETYCLLI---GGDDGACKSGGYKSKDYGSGNVG 410
           Q  EY+QLLDIK+ LE EI+TY  L+   G   G  + GG     YG G+ G
Sbjct: 428 QNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSG 479



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 10/60 (16%)

Query: 24  YGGGTSFGT----------GNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGFTVNERG 73
           YGGG+S G           G S G  G G G  S+ GGSSSGG  GGG+   G   +  G
Sbjct: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 22/44 (50%), Positives = 28/44 (63%), Gaps = 3/44 (6%)

Query: 24  YGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGF 67
           YGGG+S G G+S G  G G G SS  GG   GG++GGG+   G+
Sbjct: 473 YGGGSS-GGGSSGGGHGGGHGGSS--GGGYGGGSSGGGSSGGGY 513



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 33/88 (37%), Positives = 40/88 (45%), Gaps = 20/88 (22%)

Query: 1  MSLRLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGI---------GSGFSSA--F 49
          MS+R SS+   S       S R  GGG   G G   G+S +         G GFSS    
Sbjct: 1  MSVRYSSSKHYS-------SSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFS 53

Query: 50 GGSSSGGNTGGGNPCAGFTVNERGLLSG 77
          GGS S G++GGG  C G +    G L G
Sbjct: 54 GGSFSRGSSGGG--CFGGSSGGYGGLGG 79



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 22/43 (51%), Positives = 25/43 (58%), Gaps = 3/43 (6%)

Query: 24  YGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAG 66
           YGGG+S G G+S G  G G G SS   G SS G  GGG+   G
Sbjct: 499 YGGGSS-GGGSSGG--GYGGGSSSGGHGGSSSGGYGGGSSGGG 538



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 20/44 (45%), Positives = 24/44 (54%)

Query: 23  LYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAG 66
           L G G+S G G   G  G G G  S+ GGSS GG+ GG    +G
Sbjct: 453 LEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSG 496



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 18/36 (50%), Positives = 21/36 (58%), Gaps = 2/36 (5%)

Query: 24  YGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTG 59
           YGGG+S G  +S G  G G G SS    SSS G+ G
Sbjct: 542 YGGGSSGGGSSSGG--GYGGGSSSGGHKSSSSGSVG 575


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  420 bits (1079), Expect = e-117
 Identities = 236/478 (49%), Positives = 318/478 (66%), Gaps = 35/478 (7%)

Query: 1   MSLRLSSASRRSCPRPTTGSLRLYG-GGTSFGTGNSCG---------------------- 37
           +S RLSS S    PR  + S    G GG++FG G SCG                      
Sbjct: 17  LSRRLSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSS 76

Query: 38  -ISGIGSGFSSAFGGSSSGG-NTG-GGNPCAG----FTVNERGLLSGNEKVTMQNLNDRL 90
              G+G+G+  A GG S GG   G GG+P  G     + N+ GLLSG+EK TMQNLNDRL
Sbjct: 77  MAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRL 136

Query: 91  ASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTS 150
           ASYLD V ALEEAN +LE KI+ WYE  G G+      DYS+Y+P+I+DL+N+II+++  
Sbjct: 137 ASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIG 196

Query: 151 NANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETL 210
           NA  +LQIDNARL A+DFR+KYENELAL Q VEAD+NGLRRVLDE+TL RTDLE+Q E+L
Sbjct: 197 NAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESL 256

Query: 211 SEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDA 270
           +EE+ Y+KKNH++E+Q  +    G V+VEM+AAPGVDLT LLN+MRA+YE +AEQNR+DA
Sbjct: 257 NEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDA 316

Query: 271 EAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTET 330
           EAWF EKS  L+++IS +     S+++E+T+++R  Q LEIELQS LA K SLE SL E 
Sbjct: 317 EAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEA 376

Query: 331 ESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGD 390
           E +YCAQL+Q+Q  I  LE QL QVR + E Q +++++LL++K  LE EIETY  L+ G+
Sbjct: 377 EGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGE 436

Query: 391 ---DGACKSGGYKSKDYGSGNVGSQVKDPAKAIVVKKVLEEVDQRSKILTTRLHSLEE 445
              DG  +   + +            KDP K   +K V++E+    +++++++  +EE
Sbjct: 437 AQGDG-LEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEM-VNGEVVSSQVQEIEE 492


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  409 bits (1052), Expect = e-114
 Identities = 230/425 (54%), Positives = 285/425 (67%), Gaps = 26/425 (6%)

Query: 2   SLRLSSA-SRRSCPRPTTGSLRLYGGGTS----FGTGNSCGISG-----------IGSGF 45
           S R+SS  +  SC  P+T     YGGG S    F +G +CG+ G            GSGF
Sbjct: 28  SSRISSVLAGGSCRAPST-----YGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGF 82

Query: 46  SSAFGGSSSGGNTGG-GNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEAN 104
              +GG    G  GG G    G      GLL G+EKVTMQNLNDRLASYLD V ALEEAN
Sbjct: 83  GGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEAN 142

Query: 105 ADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLT 164
           ADLE KI+ WY++  P   +    DYS YF  I+DL+N+IIA+T  NA  +LQIDNARL 
Sbjct: 143 ADLEVKIRDWYQRQRPSEIK----DYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLA 198

Query: 165 ADDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEE 224
           ADDFR KYE+ELAL Q+VEADVNGLRRVLDE+TL RTDLE+Q E L EE+ YL+KNH+EE
Sbjct: 199 ADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEE 258

Query: 225 MQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQ 284
           M  L+   GG+VNVEM+AAPGVDL+ +LN MR +YE +AE+NRRDAE WF  K+  L ++
Sbjct: 259 MLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKE 318

Query: 285 ISEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQ 344
           ++ +     S+R+E+TE++R LQ LEIELQS L+ K SLE SL ET+  YC QL+QIQ  
Sbjct: 319 VASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGL 378

Query: 345 IGALEEQLHQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDY 404
           IG++EEQL Q+R E E Q  EY+ LLD+K  LE+EI TY  L+ G+D    S     + Y
Sbjct: 379 IGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQASGQSY 438

Query: 405 GSGNV 409
            S  V
Sbjct: 439 SSREV 443


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  403 bits (1036), Expect = e-112
 Identities = 234/461 (50%), Positives = 300/461 (65%), Gaps = 31/461 (6%)

Query: 2   SLRLSSA-SRRSCPRPTTGSLRLYGGGTS-----FGTGNSCGISG-IGSGFSSA------ 48
           S R+SS  +  SC  P+T     YGGG S     F +G + G+ G  G GFSS+      
Sbjct: 28  SSRISSVLAGGSCRAPST-----YGGGLSVSSSRFSSGGAYGLGGGYGGGFSSSSSSFGS 82

Query: 49  -FGGSSSGG-NTGGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANAD 106
            FGG   GG   G G    G      GLL G+EKVTMQNLNDRLASYLD V ALEEANAD
Sbjct: 83  GFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANAD 142

Query: 107 LEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTAD 166
           LE KI+ WY++  P   +    DYS YF  I+DL+N+I+ +T  NAN +LQIDNARL AD
Sbjct: 143 LEVKIRDWYQRQRPAEIK----DYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAAD 198

Query: 167 DFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQ 226
           DFR KYE EL L  SVEAD+NGLRRVLDE+TL R DLE+Q E+L EE+ YLKKNH+EEM 
Sbjct: 199 DFRTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMN 258

Query: 227 VLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQIS 286
            L+   GG+VNVEM+AAPGVDL+ +LN MR +YE +AE+NR+DAE WF  K+  L ++++
Sbjct: 259 ALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVA 318

Query: 287 EDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIG 346
            +     S ++E++E++RT+Q LEIELQS L+ K SLE SL ET+  YC QLAQIQ  IG
Sbjct: 319 TNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIG 378

Query: 347 ALEEQLHQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGS 406
           ++EEQL Q+R E E Q  EY+ LLD+K  LE+EI TY  L+ G+D    S  + S    S
Sbjct: 379 SVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSSGSQSS 438

Query: 407 GNVGSQVKDPAKAIVVKKVLEEVDQRSKILTTRLHSLEEKS 447
            +V S  +      +  KV++  D   K+++T    L  K+
Sbjct: 439 RDVTSSSRQ-----IRTKVMDVHD--GKVVSTHEQVLRTKN 472


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  401 bits (1031), Expect = e-112
 Identities = 216/395 (54%), Positives = 268/395 (67%), Gaps = 7/395 (1%)

Query: 17  TTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGFTVNERGLLS 76
           +  S R    G+  G G    + G G G  S FGG   GG  GG     GF   + GLLS
Sbjct: 45  SASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFG--GGFGGGDGGLLS 102

Query: 77  GNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPI 136
           GNEK+TMQNLNDRLASYLD V ALEEANADLE KI  WY+K  P S    + DYS+YF  
Sbjct: 103 GNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSP---ECDYSQYFKT 159

Query: 137 IDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEI 196
           I++L+++I+A+T  N+  +L+IDNARL ADDFRLKYENELAL Q VEAD+NGLRRVLDE+
Sbjct: 160 IEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDEL 219

Query: 197 TLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMR 256
           TL RTDLE+Q E L+EE+ YLKKNH+EEM+       G VNVEM+AAPGVDLT +L  MR
Sbjct: 220 TLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMR 279

Query: 257 AEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQSL 316
            +YEA+AE+NRRD EAWF  K+  L ++++ +     +++ E+T+++RT+Q LEIELQS 
Sbjct: 280 EQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQ 339

Query: 317 LATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKLHL 376
           L+ K  LE SL ETE  Y  QL QIQ  IG LE QL ++R E E Q  EY+ LLDIK  L
Sbjct: 340 LSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRL 399

Query: 377 EKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGS 411
           E+EI TY  L+ G D   K  G   ++  SG  GS
Sbjct: 400 EQEIATYRSLLEGQD--AKMAGIGIREASSGGGGS 432


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  390 bits (1003), Expect = e-108
 Identities = 209/378 (55%), Positives = 265/378 (70%), Gaps = 9/378 (2%)

Query: 19  GSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG-GNPCAG----FTVNERG 73
           GS   YGGG S G G   G SG G G+    GG   GG  GG G   AG    F   + G
Sbjct: 40  GSAGGYGGGVSCGFGGGAG-SGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98

Query: 74  LLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRY 133
           LL+GNEK+TMQNLNDRLASYL+ V ALEEANADLE KI+ W+ K  P S    + DYS Y
Sbjct: 99  LLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASP---ERDYSPY 155

Query: 134 FPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVL 193
           +  I++L+++I+ +T  N   +L+IDNARL ADDFRLKYENELAL QSVEAD+NGLRRVL
Sbjct: 156 YKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVL 215

Query: 194 DEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLN 253
           DE+TL +TDLE+Q E+L+EE+ Y+KKNH+EEM+       G VNVEM+A PG+DLT +L 
Sbjct: 216 DELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLA 275

Query: 254 NMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIEL 313
            MR +YEA+AE+NRRDAE WF+ KSA L +++S +     +++ E+TE++RTLQ LEIEL
Sbjct: 276 EMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIEL 335

Query: 314 QSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIK 373
           QS L+ K  LE ++ ETE  Y  QL QIQ  I ++E QL ++R+E E Q  EY+ LLDIK
Sbjct: 336 QSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIK 395

Query: 374 LHLEKEIETYCLLIGGDD 391
             LE+EI TY  L+ G D
Sbjct: 396 TRLEQEIATYRSLLEGQD 413


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  390 bits (1003), Expect = e-108
 Identities = 209/378 (55%), Positives = 265/378 (70%), Gaps = 9/378 (2%)

Query: 19  GSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG-GNPCAG----FTVNERG 73
           GS   YGGG S G G   G SG G G+    GG   GG  GG G   AG    F   + G
Sbjct: 40  GSAGGYGGGVSCGFGGGAG-SGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGG 98

Query: 74  LLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRY 133
           LL+GNEK+TMQNLNDRLASYL+ V ALEEANADLE KI+ W+ K  P S    + DYS Y
Sbjct: 99  LLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASP---ERDYSPY 155

Query: 134 FPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVL 193
           +  I++L+++I+ +T  N   +L+IDNARL ADDFRLKYENELAL QSVEAD+NGLRRVL
Sbjct: 156 YKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVL 215

Query: 194 DEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLN 253
           DE+TL +TDLE+Q E+L+EE+ Y+KKNH+EEM+       G VNVEM+A PG+DLT +L 
Sbjct: 216 DELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLA 275

Query: 254 NMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIEL 313
            MR +YEA+AE+NRRDAE WF+ KSA L +++S +     +++ E+TE++RTLQ LEIEL
Sbjct: 276 EMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIEL 335

Query: 314 QSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIK 373
           QS L+ K  LE ++ ETE  Y  QL QIQ  I ++E QL ++R+E E Q  EY+ LLDIK
Sbjct: 336 QSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIK 395

Query: 374 LHLEKEIETYCLLIGGDD 391
             LE+EI TY  L+ G D
Sbjct: 396 TRLEQEIATYRSLLEGQD 413


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  385 bits (988), Expect = e-107
 Identities = 215/439 (48%), Positives = 285/439 (64%), Gaps = 43/439 (9%)

Query: 2   SLRLSSA-SRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG 60
           S RLS      SC   + G L    GG+S+   +SC   G G G+ S+FGG         
Sbjct: 28  SCRLSGGLGAGSCRLGSAGGLGSTLGGSSY---SSCYSFGSGGGYGSSFGGVD------- 77

Query: 61  GNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGP 120
                       GLL+G EK TMQNLNDRLASYLD V ALEEAN +LE KI+ WY++  P
Sbjct: 78  ------------GLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAP 125

Query: 121 GSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQ 180
           G  R    DYS+Y+  I++L+N+I+ +T  NAN +LQIDNARL ADDFR K+E E AL  
Sbjct: 126 GPAR----DYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRL 181

Query: 181 SVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEM 240
           SVEAD+NGLRRVLDE+TL R DLE+Q E L EE+ YLKKNH+EEM  L+   GG +NVEM
Sbjct: 182 SVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEM 241

Query: 241 NAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELT 300
           +AAPGVDL+ +LN MR +YE +AE+NR+DAE WF  K+  L ++++ +     S ++E++
Sbjct: 242 DAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEIS 301

Query: 301 EMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETE 360
           E++RT+Q LEIELQS L+ K SLE +L ETE+ YC QL+QIQ  IG++EEQL Q+R E E
Sbjct: 302 ELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEME 361

Query: 361 GQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAI 420
            Q  EY+ LLD+K  LE+EI TY  L+ G+D                ++    K+P    
Sbjct: 362 QQNQEYKILLDVKTRLEQEIATYRRLLEGED---------------AHLTQYKKEPVTTR 406

Query: 421 VVKKVLEEVDQRSKILTTR 439
            V+ ++EEV Q  K++++R
Sbjct: 407 QVRTIVEEV-QDGKVISSR 424


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  369 bits (946), Expect = e-102
 Identities = 201/377 (53%), Positives = 259/377 (68%), Gaps = 14/377 (3%)

Query: 23  LYGGGTSFGTGNSC-------GISGIGSGFSSA-FGGSSSGGNTGGGNPCAGFTVNERGL 74
           L GG   FG G +        G  G G   SSA F  SSS G  GGG    G      GL
Sbjct: 18  LGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGY--GGVLTASDGL 75

Query: 75  LSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYF 134
           L+GNEK+TMQNLNDRLASYLD V ALE AN +LE KI+ WY+K GPG  R    DYS Y+
Sbjct: 76  LAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSR----DYSHYY 131

Query: 135 PIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLD 194
             I DL+++I+ +T  N+  VLQIDNARL ADDFR K+E E AL  SVEAD+NGLRRVLD
Sbjct: 132 TTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLD 191

Query: 195 EITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNN 254
           E+TL RTDLE+Q E L EE+ YLKKNH+EE+  L+   GG V+VE+++APG DL  +L++
Sbjct: 192 ELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSD 251

Query: 255 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQ 314
           MR++YE +AEQNR+DAEAWF  ++  L ++++        +R+E+T+++RTLQ LEIELQ
Sbjct: 252 MRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQ 311

Query: 315 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKL 374
           S L+ K +LE +L ETE+ + AQLA IQA I  +E QL  VR ++E Q  EY++L+DIK 
Sbjct: 312 SQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKS 371

Query: 375 HLEKEIETYCLLIGGDD 391
            LE+EI TY  L+ G +
Sbjct: 372 RLEQEIATYRSLLEGQE 388


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  339 bits (870), Expect = 3e-93
 Identities = 195/395 (49%), Positives = 246/395 (62%), Gaps = 13/395 (3%)

Query: 25  GGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGG-GNPCAGFTV-------NERGLLS 76
           GG   FG  +  G S  G GF   FGG S GG  GG G+   GF          + G+L+
Sbjct: 92  GGSRGFGGASGGGYSSSG-GFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILT 150

Query: 77  GNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPI 136
            NEK TMQ LN RLASYLD V ALEEAN DLE KI+ WY+K GP +   +  +YS Y+  
Sbjct: 151 ANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAA---IQKNYSPYYNT 207

Query: 137 IDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEI 196
           IDDLK+QI+  T  N   +L IDN R+T DDFR+K+E E  L Q V+AD+NGLR+VLD +
Sbjct: 208 IDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNL 267

Query: 197 TLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMR 256
           T+ ++DLE+QYETL EE+  LKKNHKEEM  L     G+VNVE+N APG DLT  LN+MR
Sbjct: 268 TMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMR 327

Query: 257 AEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQSL 316
            EYE L  +NR+D E  +  +   ++ ++S       S+  E+T+++  +Q LEIELQS 
Sbjct: 328 QEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQ 387

Query: 317 LATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKLHL 376
           L+ K +LE SL +T++ YC QL  IQ QI  LE Q+  VR E E Q  EY  LL IK+ L
Sbjct: 388 LSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRL 447

Query: 377 EKEIETY-CLLIGGDDGACKSGGYKSKDYGSGNVG 410
           EKEIETY  LL GG +    SG  K    G G  G
Sbjct: 448 EKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSG 482



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 22/53 (41%), Positives = 25/53 (47%)

Query: 25  GGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGFTVNERGLLSG 77
           G G S+G G S G  G GSG     GGS  GG+  GG    G+     G  SG
Sbjct: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSG 544



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 4/52 (7%)

Query: 19  GSLRLYGGGTSFGTGNSCGI-SGIGSGFSSAFGG---SSSGGNTGGGNPCAG 66
           GS   YGGG+  G G+  G   G G G S   GG     SGGN GGG+   G
Sbjct: 515 GSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGG 566



 Score = 35.8 bits (81), Expect = 0.081
 Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 1/49 (2%)

Query: 19  GSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGG-SSSGGNTGGGNPCAG 66
           GS   YG G+  G+G S G  G G G+    G    SGG+ GGG+   G
Sbjct: 480 GSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528



 Score = 35.8 bits (81), Expect = 0.081
 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 19  GSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGFTVNERGLLSG 77
           GS   YGGG+  G G+  G  G GSG     GGS  GG+  GG     +   E    SG
Sbjct: 553 GSGGNYGGGSGSGGGSGGGYGG-GSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSG 610



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 23/61 (37%), Positives = 29/61 (47%), Gaps = 3/61 (4%)

Query: 25  GGGTSFGTG-NSCGISGIGSGFSSAFGGSSS--GGNTGGGNPCAGFTVNERGLLSGNEKV 81
           GGG S G+G N  G SG G G    +GG S   GG+ G     +GF     G   G E+ 
Sbjct: 547 GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEA 606

Query: 82  T 82
           +
Sbjct: 607 S 607



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 82/413 (19%), Positives = 153/413 (37%), Gaps = 58/413 (14%)

Query: 12  SCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGG-------SSSGGNTGGGNPC 64
           SC + ++  L   GGG   G G+   I    S FSS+ GG       SSSG   G    C
Sbjct: 2   SCRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVC 61

Query: 65  AGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCR 124
                   G   G       + +     +         A+        G+   FG GS  
Sbjct: 62  GRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGG 121

Query: 125 GLDHDYSRYFPIIDDLKNQIIAS----TTSNANAVLQIDNARLTA--------DDFRLKY 172
           G    Y   F                  T+N  + +Q  N+RL +        ++     
Sbjct: 122 GFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDL 181

Query: 173 ENEL----------ALHQSVEADVNGLRRVLDEITLC-----RTDLEIQYETLSEEMTYL 217
           EN++          A+ ++     N +  + D+I        +T L+I    ++ +   +
Sbjct: 182 ENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRI 241

Query: 218 KKNHKEEMQVLQCAAGGNVNVEMNAAPGV--DLTVLLNNMRAEYEALAEQNRRDAEAWFN 275
           K   ++ ++         V+ ++N    V  +LT+  +++  +YE L E+     +    
Sbjct: 242 KFEMEQNLR-------QGVDADINGLRQVLDNLTMEKSDLEMQYETLQEE-LMALKKNHK 293

Query: 276 EKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYC 335
           E+ + L  Q S DV    +      ++ +TL  +  E + L+A          + E+ Y 
Sbjct: 294 EEMSQLTGQNSGDVNVEINVAPG-KDLTKTLNDMRQEYEQLIAKNRK------DIENQYE 346

Query: 336 AQLAQIQAQIGALEEQLH-------QVRTETEGQKLEYEQLLDIKLHLEKEIE 381
            Q+ QI+ ++ +  +++        Q+R   +  ++E +  L  K  LEK +E
Sbjct: 347 TQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLE 399



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 21/40 (52%), Positives = 24/40 (60%), Gaps = 4/40 (10%)

Query: 24  YGGGTSFGTGNSCGISGIGSGFSSAF--GGSSSGGNTGGG 61
           YGGG+  G G+S G  G  SG S     GGS SGG +GGG
Sbjct: 534 YGGGS--GGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGG 571



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 2/50 (4%)

Query: 31  GTGNSCGISGIGS--GFSSAFGGSSSGGNTGGGNPCAGFTVNERGLLSGN 78
           G G S G  G GS  G   ++GG  SGG  GGG+   G +    G  SG+
Sbjct: 477 GRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGS 526



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 21/45 (46%), Positives = 23/45 (51%), Gaps = 5/45 (11%)

Query: 19  GSLRLYGGGTSFGT--GNSCGISGIGSGFSSAFGGSSSGGNTGGG 61
           GS   YGGG S G   G S    G G  +    GGS SGG +GGG
Sbjct: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYG---GGSGSGGGSGGG 533



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 6/45 (13%)

Query: 24  YGGGTSF--GTGNSCGI-SGIGSGFSSAFGGSSSGG---NTGGGN 62
           YGGG+    G+G S G  SG G G    +GG S GG    +GGG+
Sbjct: 506 YGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGH 550


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  328 bits (841), Expect = 6e-90
 Identities = 182/384 (47%), Positives = 245/384 (63%), Gaps = 18/384 (4%)

Query: 17  TTGSLRL--YGGGTSFGTGNSCGISGIGSGFSSAFGGS---SSGGNTGGGNPCAGFTVNE 71
           + GS R+    G   + +    G+SG+GS    ++  S   +SG    GG  C       
Sbjct: 33  SVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFC------- 85

Query: 72  RGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYS 131
            G  +G+EK TMQ LNDRLA+YL+ V  LE  NA+LE +I+ WYE   P  C     DY 
Sbjct: 86  EGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICP----DYQ 141

Query: 132 RYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRR 191
            YF  I+D + +I+ + + NA  VLQIDNA+L ADDFR KYE EL+L Q VEAD+NGLRR
Sbjct: 142 SYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRR 201

Query: 192 VLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVL 251
           +LDE+TLC+ DLE Q E+L EE+  LKKNH+EE+ VL+C  G  +NVE++AAP VDL  +
Sbjct: 202 ILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKI 261

Query: 252 LNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEI 311
           L +MR +YEAL E NRRD EAWFN ++  L QQ+          + E+ E++RT+  LEI
Sbjct: 262 LEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEI 321

Query: 312 ELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLD 371
           ELQ+  + ++SLE +L ETE+ Y +QLAQ+Q  I  +E QL ++R + E Q  EY+ LLD
Sbjct: 322 ELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLD 381

Query: 372 IKLHLEKEIETYCLLIGGDDGACK 395
           +K  LE EI TY  L+ G+D  CK
Sbjct: 382 VKARLEGEIATYRHLLEGED--CK 403


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  308 bits (788), Expect = 8e-84
 Identities = 173/399 (43%), Positives = 242/399 (60%), Gaps = 27/399 (6%)

Query: 2   SLRLSSA-SRRSCPRPTTGSLRLYGGGTSFGTGNSC--------GISGIGSGFSSAFGGS 52
           S R+S+  S  SC  P+   +       S G G S          +     GF++++ G 
Sbjct: 25  STRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALCLPAGGFATSYSG- 83

Query: 53  SSGGNTGGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIK 112
             GG   G            G+L+GNEK TMQ+LNDRLA YL+ V  LE+ NA LE +I+
Sbjct: 84  --GGGWFG-----------EGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIR 130

Query: 113 GWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKY 172
            W E+  P  C     DY  YF  I++L+ + + S   NA  V++IDNA+L ADDFR KY
Sbjct: 131 EWCEQQVPYMCP----DYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKY 186

Query: 173 ENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAA 232
           E E++L Q VE+D+NGLRR+LD++TLC++DLE Q E+L EE+  LKKNH+EE+  L+C  
Sbjct: 187 ETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQL 246

Query: 233 GGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGAT 292
           G  +NVE++AAP VDL  +L  MR +YE L E NRRDAE W + +S  L QQ+       
Sbjct: 247 GDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQL 306

Query: 293 TSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQL 352
            S + E+ E++RT+  LEIELQ+  + + +LE +L ETE+ Y +QLAQ+Q  I  +E QL
Sbjct: 307 QSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQL 366

Query: 353 HQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDD 391
            ++R + E Q  EY+ LLD++  LE EI TY  L+  +D
Sbjct: 367 AEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESED 405


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  304 bits (779), Expect = 9e-83
 Identities = 188/444 (42%), Positives = 273/444 (61%), Gaps = 32/444 (7%)

Query: 9   SRRSCPRPTTGSLRL----YGGGTSFGTGNSC--GISGIGSGFSSAFGGSSSGGN-TGGG 61
           SRRS  R  + SL+       G    GT  S   G  G G   S++    + G + TGGG
Sbjct: 4   SRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGGG 63

Query: 62  NPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPG 121
           +           L  GNEK+ MQNLNDRLASYL+ V  LE++N+ LE +IK WYE   P 
Sbjct: 64  D-----------LFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPR 112

Query: 122 SCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQS 181
           + R    DYS Y+  I++L++QI  +   NA  VLQIDNA+L A+DFRLKYE E  +  +
Sbjct: 113 AGR----DYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLT 168

Query: 182 VEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMN 241
           VEAD+ GL +V D++TL +TDLEIQ E L++++  LKK H+EE+  L    G  VNVE++
Sbjct: 169 VEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVD 228

Query: 242 AAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTE 301
           AAPG++L V++N MR +YE +A++N ++A+  F  ++A LQQQ++ +         +LTE
Sbjct: 229 AAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTE 288

Query: 302 MKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEG 361
           ++RT Q+LEIELQS L+ K SLE +L ET++ Y +QLA +Q+ + +LE QL Q+R+  E 
Sbjct: 289 LRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMER 348

Query: 362 QKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAIV 421
           Q  EY  LLDIK  LE+EI TY  L+ G+D        K+ +Y    +  + +D  K   
Sbjct: 349 QNNEYHILLDIKTRLEQEIATYRRLLEGED-------VKTTEYQLSTL--EERDIKKTRK 399

Query: 422 VKKVLEEVDQRSKILTTRLHSLEE 445
           +K V++EV    K++++ +  +EE
Sbjct: 400 IKTVVQEVVD-GKVVSSEVKEVEE 422


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  297 bits (760), Expect = 1e-80
 Identities = 157/343 (45%), Positives = 226/343 (65%), Gaps = 9/343 (2%)

Query: 53  SSGGNTGGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIK 112
           ++ G +G   P + ++    G  +GNEK TMQ LNDRLASYL  V  LE+ NA+LE +I 
Sbjct: 73  AASGISGSMGPGSWYS---EGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRI- 128

Query: 113 GWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKY 172
              ++        +  DY  +F  I++L+ +I+ +   NA  V+ IDNA+L ADDFR KY
Sbjct: 129 ---QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKY 185

Query: 173 ENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAA 232
           E ELA+ Q VEAD+NGLRR+LD++TLC+ DLE Q E+L EE+  LKKNH+EE+  L+C  
Sbjct: 186 EAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQL 245

Query: 233 GGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGAT 292
           G  +N+E++AAP VDLT +L  MR +YEA+ E NRRD E WFN +   L QQ++      
Sbjct: 246 GDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQL 305

Query: 293 TSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQL 352
            + ++++ +++RT+ TLEIELQ+  + + SLE +LTE+E+ Y +QLAQ+Q  I  +E QL
Sbjct: 306 QNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQL 365

Query: 353 HQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACK 395
            ++R + E Q  EY+ LLD++  LE EI TY  L+  +D  CK
Sbjct: 366 AEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENED--CK 406


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  291 bits (746), Expect = 6e-79
 Identities = 154/323 (47%), Positives = 217/323 (67%), Gaps = 6/323 (1%)

Query: 73  GLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSR 132
           G  +G+EK TMQ LNDRLASYL+ V  LE  NA+LE  I+   ++  P  C      Y  
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCAS----YQS 105

Query: 133 YFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRV 192
           YF  I++L+ +I+ S + NA  V+QIDNA+L +DDFR KYE EL+L Q VE+D+NGLRR+
Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRI 165

Query: 193 LDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLL 252
           LDE+TLCR+DLE Q E+L EE+  LK+NH++E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 166 LDELTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVL 225

Query: 253 NNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIE 312
           N  R++YEAL E NRR+ E WF  ++  L +Q+        S + E+ E++RT+  LEIE
Sbjct: 226 NETRSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 313 LQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDI 372
           LQ+    + SLE +LTE+E+ Y +QL+Q+Q  I  +E QL ++R++ E Q  EY+ LLD+
Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 373 KLHLEKEIETYCLLIGGDDGACK 395
           +  LE EI TY  L+  +D  CK
Sbjct: 346 RARLECEINTYRSLLESED--CK 366


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  291 bits (745), Expect = 8e-79
 Identities = 155/349 (44%), Positives = 226/349 (64%), Gaps = 4/349 (1%)

Query: 73  GLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSR 132
           G  +G+EK TMQ LNDRLASYL+ V  LE  NA+LE  I+   ++  P  C      Y  
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105

Query: 133 YFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRV 192
           YF  I++L+ +I+ + + NA  V+QIDNA+L ADDFR KY+ EL+L Q VE+D+NGLRR+
Sbjct: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165

Query: 193 LDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLL 252
           LDE+TLC++DLE Q E+L EE+  LK NH++E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225

Query: 253 NNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIE 312
           N  R++YEAL E NRR+ E WF  ++  L +Q+        S + E+ E++RT+  LEIE
Sbjct: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 313 LQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDI 372
           LQ+    + SLE +LTE+E+ Y +QL+Q+Q+ I  +E QL ++R++ E Q  EY+ LLD+
Sbjct: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 373 KLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAIV 421
           +  LE EI TY  L+  +D    S    + +  S  +G  + +P  + V
Sbjct: 346 RARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCV 394


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  290 bits (742), Expect = 2e-78
 Identities = 155/344 (45%), Positives = 223/344 (64%), Gaps = 4/344 (1%)

Query: 73  GLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSR 132
           G  +G+EK TMQ LNDRLASYL+ V  LE  NA+LE  I+   ++  P  C      Y  
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105

Query: 133 YFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRV 192
           YF  I++L+ +I+ S + NA  V+QIDNA+L ADDFR KY+ E +L Q VE+D+N LRR+
Sbjct: 106 YFKTIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRI 165

Query: 193 LDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLL 252
           LDE+TLCR+DLE Q E+L EE+  LK+NH++E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 166 LDELTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVL 225

Query: 253 NNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIE 312
           N  R +YEAL E NRR+ E WF  ++  L +Q+        S + E+ E++RT+  LEIE
Sbjct: 226 NETRNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285

Query: 313 LQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDI 372
           LQ+    ++SLE +LTE+E+ Y +QL+Q+Q+ I  +E QL ++R++ E Q  EY+ LLD+
Sbjct: 286 LQAQHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345

Query: 373 KLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDP 416
           +  LE EI TY  L+  +D    S    + +     +GS V +P
Sbjct: 346 RARLECEINTYRSLLESEDCKLPSNPCATTNACEKPIGSCVTNP 389


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  274 bits (700), Expect = 1e-73
 Identities = 146/323 (45%), Positives = 212/323 (65%), Gaps = 6/323 (1%)

Query: 73  GLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSR 132
           G  +G+EK TMQ LNDRLASYL+ V  LE  NA+LE+ I+   ++  P  C      Y  
Sbjct: 92  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPS----YQS 147

Query: 133 YFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRV 192
           YF  I++L+ +I+ +   NA  V+ IDNA+L +DDFR KY+ E +L   VE+D+N +RR+
Sbjct: 148 YFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRI 207

Query: 193 LDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLL 252
           LDE+TLC++DLE Q E+L EE+  LKKNH+EE+  L+   G  +NVE++ AP VDL  +L
Sbjct: 208 LDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVL 267

Query: 253 NNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIE 312
           N  R++YEAL E NRR+ E WF  ++  L +Q+        S + E+ E++RT+  LEIE
Sbjct: 268 NETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIE 327

Query: 313 LQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDI 372
           LQ+    + SLE +LTE+E++Y +QL+Q+Q+ I  +E QL ++R + E Q  EY+ LLD+
Sbjct: 328 LQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDV 387

Query: 373 KLHLEKEIETYCLLIGGDDGACK 395
           +  LE EI TY  L+  +D  CK
Sbjct: 388 RARLECEINTYRSLLESED--CK 408


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  273 bits (698), Expect = 2e-73
 Identities = 143/321 (44%), Positives = 206/321 (64%), Gaps = 4/321 (1%)

Query: 71  ERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDY 130
           E G+ + NEK TMQ LNDRLASYL+ V +LEE NA+LE +I+   E+  P  C     DY
Sbjct: 81  EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP----DY 136

Query: 131 SRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLR 190
            RYF  I+DL+ +I+ +   N+   +Q+DN +L  DDF+ KYE+EL+L Q +EAD++ L 
Sbjct: 137 QRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLH 196

Query: 191 RVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTV 250
            +L+E+TLC++DLE   E+L E++  LKKNH+EE+ +L+   G  ++VE++ AP +DL  
Sbjct: 197 GILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNR 256

Query: 251 LLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLE 310
           +L+ MR + E +   NRR+AE W   ++  L QQ           + E+ E+KRT   LE
Sbjct: 257 VLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALE 316

Query: 311 IELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLL 370
           IELQ+  +   SLEC++ ETE+ Y +QLAQIQ  I  LE QL ++R + E Q  EY+ LL
Sbjct: 317 IELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLL 376

Query: 371 DIKLHLEKEIETYCLLIGGDD 391
           D+K  LE EI TY  L+  +D
Sbjct: 377 DVKARLEGEINTYWGLLDSED 397


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  271 bits (692), Expect = 1e-72
 Identities = 150/344 (43%), Positives = 205/344 (59%), Gaps = 21/344 (6%)

Query: 75  LSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYF 134
           ++ NEK TMQ LN+RLA+YL  V  LE  NA+LE KI+    K  P  C     DY  Y+
Sbjct: 92  INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP----DYLSYY 147

Query: 135 PIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLD 194
             I++L+ +I+ +   N+  V QIDN +LTADD R KYE E++L Q VE+D NGL+++L+
Sbjct: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207

Query: 195 EITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNN 254
            +TL + DLE Q ++L EE+  LK NHKEE+  LQC  G  +++E+ AAP  DL  +L  
Sbjct: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267

Query: 255 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQ 314
           MR +YE + E NR+D E WFN +   L QQ+          + E+ E++R++ TLE+ELQ
Sbjct: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327

Query: 315 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKL 374
           +    + S EC LTETE+ Y A L QIQ+ I  LE QL ++R   E Q  EYE LLD+K 
Sbjct: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387

Query: 375 HLEKEIETYCLLIGGDDG-----------------ACKSGGYKS 401
            LE EI TY  L+   DG                 +CKSG  +S
Sbjct: 388 RLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIES 431


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  270 bits (691), Expect = 2e-72
 Identities = 171/383 (44%), Positives = 236/383 (61%), Gaps = 26/383 (6%)

Query: 15  RPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAF-GGSSSGGNTGGGNPCAGFTVNERG 73
           RP + +  +Y G    G+G+   +S      S++F GG  SGG   G    AG      G
Sbjct: 27  RPVSSAASVYAGAG--GSGSRISVSR-----STSFRGGMGSGGLATG---IAGGLAGMGG 76

Query: 74  LLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRY 133
           +   NEK TMQ+LNDRLASYLD V +LE  N  LE KI+   EK GP        D+S Y
Sbjct: 77  IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-----RDWSHY 129

Query: 134 FPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVL 193
           F II+DL+ QI A+T  NA  VLQIDNARL ADDFR+KYE ELA+ QSVE D++GLR+V+
Sbjct: 130 FKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVI 189

Query: 194 DEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQC-AAGGNVNVEMNAAPGVDLTVLL 252
           D+  + R  LE + E L EE+ ++KKNH+EE++ LQ   A   + VE++A    DL  ++
Sbjct: 190 DDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIM 249

Query: 253 NNMRAEYEALAEQNRRDAEAWFN---EKSASLQQQISEDVGATTSARNELTEMKRTLQTL 309
            ++RA+Y+ LA +NR + + +++   E+S ++    S +VGA   A   LTE++RT+Q+L
Sbjct: 250 ADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGA---AETTLTELRRTVQSL 306

Query: 310 EIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQL 369
           EI+L S+   K SLE SL E E+ Y  Q+ Q+   +  LE +L Q R E + Q  EYE L
Sbjct: 307 EIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEAL 366

Query: 370 LDIKLHLEKEIETY-CLLIGGDD 391
           L+IK+ LE EI TY  LL  G+D
Sbjct: 367 LNIKVKLEAEIATYRRLLEDGED 389


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  270 bits (691), Expect = 2e-72
 Identities = 171/383 (44%), Positives = 236/383 (61%), Gaps = 26/383 (6%)

Query: 15  RPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAF-GGSSSGGNTGGGNPCAGFTVNERG 73
           RP + +  +Y G    G+G+   +S      S++F GG  SGG   G    AG      G
Sbjct: 27  RPVSSAASVYAGAG--GSGSRISVSR-----STSFRGGMGSGGLATG---IAGGLAGMGG 76

Query: 74  LLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRY 133
           +   NEK TMQ+LNDRLASYLD V +LE  N  LE KI+   EK GP        D+S Y
Sbjct: 77  IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-----RDWSHY 129

Query: 134 FPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVL 193
           F II+DL+ QI A+T  NA  VLQIDNARL ADDFR+KYE ELA+ QSVE D++GLR+V+
Sbjct: 130 FKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVI 189

Query: 194 DEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQC-AAGGNVNVEMNAAPGVDLTVLL 252
           D+  + R  LE + E L EE+ ++KKNH+EE++ LQ   A   + VE++A    DL  ++
Sbjct: 190 DDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIM 249

Query: 253 NNMRAEYEALAEQNRRDAEAWFN---EKSASLQQQISEDVGATTSARNELTEMKRTLQTL 309
            ++RA+Y+ LA +NR + + +++   E+S ++    S +VGA   A   LTE++RT+Q+L
Sbjct: 250 ADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGA---AETTLTELRRTVQSL 306

Query: 310 EIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQL 369
           EI+L S+   K SLE SL E E+ Y  Q+ Q+   +  LE +L Q R E + Q  EYE L
Sbjct: 307 EIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEAL 366

Query: 370 LDIKLHLEKEIETY-CLLIGGDD 391
           L+IK+ LE EI TY  LL  G+D
Sbjct: 367 LNIKVKLEAEIATYRRLLEDGED 389


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  270 bits (690), Expect = 2e-72
 Identities = 157/380 (41%), Positives = 219/380 (57%), Gaps = 21/380 (5%)

Query: 27  GTSFGTGNSCGISGIGSGFS---SAFGGSSSGGNTGGGNPCAGFTVNE------------ 71
           G SF    S    G G G+    S     +  G  GG      FT               
Sbjct: 4   GHSFSQTPSASFHGAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGR 63

Query: 72  -RGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDY 130
              LL GN K TMQNLNDRLASYL+ V ALEEAN  LE +I  W+++  PGS +    DY
Sbjct: 64  SSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKK----DY 119

Query: 131 SRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLR 190
           S+Y   I  L+ QI+    +NA  +L IDNAR+  DDF LKYENE +  + +E +V GLR
Sbjct: 120 SQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLR 179

Query: 191 RVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTV 250
           R LD +T+  TDLE + E + +E+  +KK+H++EM+     +  NVNV+++  P  DL  
Sbjct: 180 RTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIK 239

Query: 251 LLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLE 310
           +L +MR EYE + ++  RD + W+ E+SA++ Q+ +       S + ++ E+KRT Q LE
Sbjct: 240 VLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAASP-ATVQSRQGDIHELKRTFQALE 298

Query: 311 IELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLL 370
           I+LQ+  +TK +LE  L+ET+S Y  +L  +Q  I   EE+L Q+R E E Q  EY+ LL
Sbjct: 299 IDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLL 358

Query: 371 DIKLHLEKEIETYCLLIGGD 390
            IK HLEKEI TY  L+ G+
Sbjct: 359 GIKTHLEKEITTYRRLLEGE 378


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  249 bits (635), Expect = 5e-66
 Identities = 135/324 (41%), Positives = 197/324 (60%), Gaps = 6/324 (1%)

Query: 72  RGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYS 131
           +  L+G+EK TM+ LNDRLA+YL+ V  LE+ NA+LE  +    +      C     DY 
Sbjct: 97  KNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCP----DYQ 152

Query: 132 RYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRR 191
            YF  I++L+ +I+ S   NA  ++QIDNA+L ADDFR+K E+E +LHQ VEAD  G ++
Sbjct: 153 SYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQK 212

Query: 192 VLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVL 251
           +LD+ TL + DLE Q E+L EE   LK NH++E+++L+   G    +E++  P +DL  +
Sbjct: 213 LLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRV 272

Query: 252 LNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEI 311
           L  MRA+YEA+ E N +D E WF  +S  +  Q           ++E+ E++ T+  LE+
Sbjct: 273 LGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEV 332

Query: 312 ELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLD 371
           E Q+    K  L+ SL E E  Y  +LAQ+Q+ I  LEEQL ++R + E Q  EY+ LLD
Sbjct: 333 ERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLD 392

Query: 372 IKLHLEKEIETYCLLIGGDDGACK 395
           +K  LE EI TY  L+  +D  CK
Sbjct: 393 VKARLENEIATYRNLLESED--CK 414


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  246 bits (627), Expect = 4e-65
 Identities = 134/321 (41%), Positives = 197/321 (61%), Gaps = 6/321 (1%)

Query: 75  LSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYF 134
           L+G+EK TMQ LNDRLA+YL+ V  LE+ NA+LE  +    +      C     DY  YF
Sbjct: 100 LNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCP----DYQSYF 155

Query: 135 PIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLD 194
             I++L+ +I+ S   NA  ++QIDNA+L ADDFR+K E+E +L Q VEAD  G +++LD
Sbjct: 156 HTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLD 215

Query: 195 EITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNN 254
           + TL + DLE Q E+L EE   LK NH++E+++L+   G  + +E++  P +DL  +L  
Sbjct: 216 DATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGE 275

Query: 255 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQ 314
           MRA+YEA+ E NR+D E WF  +S  +  Q           ++E+ E++ T+  LE+E Q
Sbjct: 276 MRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQ 335

Query: 315 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKL 374
           +    K  L+ SL E E  +  +LAQ+Q+ I  +EEQL ++R + E Q  EY+ LLD+K 
Sbjct: 336 AQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKT 395

Query: 375 HLEKEIETYCLLIGGDDGACK 395
            LE EI TY  L+  +D  CK
Sbjct: 396 RLENEIATYRNLLESED--CK 414


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,232,800
Number of Sequences: 37866
Number of extensions: 742343
Number of successful extensions: 6440
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 324
Number of HSP's that attempted gapping in prelim test: 3682
Number of HSP's gapped (non-prelim): 1928
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.