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Search of human proteins with 31377468
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
(1830 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens] 3664 0.0
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens] 2146 0.0
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens] 1940 0.0
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens] 1166 0.0
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] 1152 0.0
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 82 5e-15
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens] 65 5e-10
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens] 65 5e-10
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens] 64 2e-09
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens] 59 3e-08
gi|157426887 dedicator of cytokinesis 6 [Homo sapiens] 59 6e-08
gi|54112429 dedicator of cytokinesis 7 [Homo sapiens] 58 7e-08
gi|9910266 kinesin family member 15 [Homo sapiens] 42 0.004
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 40 0.016
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 40 0.016
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 40 0.016
gi|39930351 dynamin binding protein [Homo sapiens] 40 0.027
gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens] 39 0.036
gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens] 39 0.036
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 39 0.061
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 39 0.061
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens] 39 0.061
gi|7662184 zinc finger homeobox 1b [Homo sapiens] 38 0.10
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 37 0.18
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 37 0.18
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 37 0.18
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 37 0.18
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 37 0.18
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 37 0.18
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] 37 0.18
>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
Length = 1830
Score = 3664 bits (9501), Expect = 0.0
Identities = 1830/1830 (100%), Positives = 1830/1830 (100%)
Query: 1 MAPWRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFP 60
MAPWRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFP
Sbjct: 1 MAPWRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFP 60
Query: 61 KSFIHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSM 120
KSFIHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSM
Sbjct: 61 KSFIHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSM 120
Query: 121 MYDLMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSV 180
MYDLMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSV
Sbjct: 121 MYDLMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSV 180
Query: 181 ISLFHAHEEATDKITERIKEEMSKDQPDYAMYSRISSSPTHSLYVFVRNFVCRIGEDAEL 240
ISLFHAHEEATDKITERIKEEMSKDQPDYAMYSRISSSPTHSLYVFVRNFVCRIGEDAEL
Sbjct: 181 ISLFHAHEEATDKITERIKEEMSKDQPDYAMYSRISSSPTHSLYVFVRNFVCRIGEDAEL 240
Query: 241 FMSLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIV 300
FMSLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIV
Sbjct: 241 FMSLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIV 300
Query: 301 RVGKMDLKDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDFL 360
RVGKMDLKDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDFL
Sbjct: 301 RVGKMDLKDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDFL 360
Query: 361 HSLLGKVIASKGDSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPG 420
HSLLGKVIASKGDSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPG
Sbjct: 361 HSLLGKVIASKGDSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPG 420
Query: 421 DVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVV 480
DVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVV
Sbjct: 421 DVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVV 480
Query: 481 YYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGT 540
YYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGT
Sbjct: 481 YYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGT 540
Query: 541 TLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVF 600
TLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVF
Sbjct: 541 TLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVF 600
Query: 601 SISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIM 660
SISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIM
Sbjct: 601 SISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIM 660
Query: 661 MEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTY 720
MEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTY
Sbjct: 661 MEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTY 720
Query: 721 LDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNL 780
LDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNL
Sbjct: 721 LDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNL 780
Query: 781 MKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMN 840
MKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMN
Sbjct: 781 MKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMN 840
Query: 841 EIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQD 900
EIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQD
Sbjct: 841 EIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQD 900
Query: 901 AAFTYHHIQEIMVQLLRTVNRTVITMGRDHILISHFVACMTAILNQMGDQHYSFYIETFQ 960
AAFTYHHIQEIMVQLLRTVNRTVITMGRDHILISHFVACMTAILNQMGDQHYSFYIETFQ
Sbjct: 901 AAFTYHHIQEIMVQLLRTVNRTVITMGRDHILISHFVACMTAILNQMGDQHYSFYIETFQ 960
Query: 961 TSSELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFLEHTN 1020
TSSELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFLEHTN
Sbjct: 961 TSSELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFLEHTN 1020
Query: 1021 FEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQN 1080
FEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQN
Sbjct: 1021 FEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQN 1080
Query: 1081 KICFIPGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEV 1140
KICFIPGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEV
Sbjct: 1081 KICFIPGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEV 1140
Query: 1141 EGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKLLDYRGVMTDESKDNR 1200
EGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKLLDYRGVMTDESKDNR
Sbjct: 1141 EGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKLLDYRGVMTDESKDNR 1200
Query: 1201 MSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCAS 1260
MSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCAS
Sbjct: 1201 MSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCAS 1260
Query: 1261 QVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQ 1320
QVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQ
Sbjct: 1261 QVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQ 1320
Query: 1321 NLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMT 1380
NLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMT
Sbjct: 1321 NLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMT 1380
Query: 1381 QFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQ 1440
QFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQ
Sbjct: 1381 QFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQ 1440
Query: 1441 RFHYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIE 1500
RFHYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIE
Sbjct: 1441 RFHYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIE 1500
Query: 1501 TMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHP 1560
TMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHP
Sbjct: 1501 TMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHP 1560
Query: 1561 EDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVR 1620
EDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVR
Sbjct: 1561 EDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVR 1620
Query: 1621 EMPDFDDRRVGRPRSMLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQ 1680
EMPDFDDRRVGRPRSMLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQ
Sbjct: 1621 EMPDFDDRRVGRPRSMLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQ 1680
Query: 1681 EEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSRKHEFMSDTNLSEHAA 1740
EEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSRKHEFMSDTNLSEHAA
Sbjct: 1681 EEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSRKHEFMSDTNLSEHAA 1740
Query: 1741 IPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTR 1800
IPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTR
Sbjct: 1741 IPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTR 1800
Query: 1801 KKVNQFFKTMLASKSAEEGKQIPDSLSTDL 1830
KKVNQFFKTMLASKSAEEGKQIPDSLSTDL
Sbjct: 1801 KKVNQFFKTMLASKSAEEGKQIPDSLSTDL 1830
>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
Length = 1865
Score = 2146 bits (5561), Expect = 0.0
Identities = 1081/1735 (62%), Positives = 1346/1735 (77%), Gaps = 22/1735 (1%)
Query: 9 KERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFPKSFIHIKE 68
+E++GVA YN+ GA +LSLQIGD V I ET WYRGY ++ K +GIFP S+IH+KE
Sbjct: 10 EEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIFPASYIHLKE 69
Query: 69 VTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSMMYDLMEWR 128
VE + E +IP ++PL QEVTTTL EW +IW+QLYV +E F V+ M+YDL+EWR
Sbjct: 70 AIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRHMIYDLIEWR 129
Query: 129 SQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSVISLFHAHE 188
SQ+LSGTLP+DELKELK+KVT+KIDYGN+IL+LDL+VRDEDGNILDP+ TS ISLF AHE
Sbjct: 130 SQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTSTISLFRAHE 189
Query: 189 EATDKITERIKEEMSKDQP-DYAMYSRISSSPTHSLYVFVRNFVCRIGEDAELFMSLYDP 247
A+ ++ ER++EE S+ Q D ++ +++P+ +L+V ++N VC+IGEDAE+ MSLYDP
Sbjct: 190 IASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDAEVLMSLYDP 249
Query: 248 NKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRVGKMDL 307
+ ISENYLVRW S G PK+I+ L+NL+ VFTDLG+KDL R+KI +CQIVRVG+M+L
Sbjct: 250 VESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQIVRVGRMEL 309
Query: 308 KDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDFLHSLLGKV 367
+D +K T GLRRPFGVAVMD+TDII GK + DE+KQHFIPF PV ENDFL +++ KV
Sbjct: 310 RDNNTRKLTSGLRRPFGVAVMDVTDIINGKVD-DEDKQHFIPFQPVAGENDFLQTVINKV 368
Query: 368 IASKG-DSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDI 426
IA+K + GQGLWVT+K+L GDI QIRK++PHLVDRTT VARK GFPEIIMPGDVRNDI
Sbjct: 369 IAAKEVNHKGQGLWVTLKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDI 428
Query: 427 YITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVVYYQVKQ 486
Y+TL+QGDFDK +KTT +NVEV + V EDGK L + I GAGD+ ++EY+SV+YYQVKQ
Sbjct: 429 YVTLVQGDFDKGSKTTAKNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQ 488
Query: 487 PRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGF 546
PRW ETVKVA+PIED+ R HLRF FRHRSS +SKDK EK FA+++VKLM+ DGTTL DG
Sbjct: 489 PRWFETVKVAIPIEDVNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGE 548
Query: 547 HDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLV 606
HDL+V K ++KK+EDA+ YL+LPS + +E KG + + S G S+D F ISTLV
Sbjct: 549 HDLIVYKAEAKKLEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLV 608
Query: 607 CSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIMMEHSQS 666
CSTKLTQNV LLGLLKWR LLQ+NL +L VDG EVVKFLQDTLDALFNIMME+S+S
Sbjct: 609 CSTKLTQNVDLLGLLKWRSNTSLLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSES 668
Query: 667 DEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTYLDTSSR 726
+ +D LVFDAL++IIGLIADRKFQHFN VLE YI++HFSATLAY KL VLK Y+D + +
Sbjct: 669 ETFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGAEK 728
Query: 727 GEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNLMKSQYK 786
E + + +KALE +FKFIVRSR LF+QLYE K + +F ES+ +LF SIN++M S
Sbjct: 729 PGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMSD 788
Query: 787 TTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMNEIVQSN 846
T+ ++ AALKY+P++++DV++VFD K LS++ EF +P L QK+ + EIV S+
Sbjct: 789 QTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIVHSD 848
Query: 847 LFKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQDAAFTYH 906
LF + +CR+ILLP++T +LK LE+++D++ C +LL+ ILEVL +D T
Sbjct: 849 LFTQHDCREILLPMMTDQLKYHLERQEDLEA-------CCQLLSHILEVLYRKDVGPTQR 901
Query: 907 HIQEIMVQLLRTVNRTVITMGRDHILISHFVACMTAILNQMGDQHYSFYIETF-QTSSEL 965
H+Q IM +LLRTVNRTVI+MGRD LI +FVACMTAIL QM D HY+ I+TF + +++
Sbjct: 902 HVQIIMEKLLRTVNRTVISMGRDSELIGNFVACMTAILRQMEDYHYAHLIKTFGKMRTDV 961
Query: 966 VDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFLEHTNFEFQL 1025
VDFLMETFIMFK+LIGKNVYP DW+ M+MVQN+VFLRAIN++A+ +N+KFL+ NFE QL
Sbjct: 962 VDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRAINQYADMLNKKFLDQANFELQL 1021
Query: 1026 WNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFI 1085
WNNYFHLAVAF+TQ+SLQLE FS AK KILNKYGDMRR IGF IRDMWY LGQ+KI FI
Sbjct: 1022 WNNYFHLAVAFLTQESLQLENFSSAKRAKILNKYGDMRRQIGFEIRDMWYNLGQHKIKFI 1081
Query: 1086 PGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRG 1145
P MVGPILEMTLIPE ELRKATIPIFFDMM CE+ + F+ FENEII KLDHEVEGGRG
Sbjct: 1082 PEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTRSFQMFENEIITKLDHEVEGGRG 1141
Query: 1146 DEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKLLDYRGVMTDESKDNRMSCTV 1205
DEQY L + IL+E +H +AK+ E FV LV L+E+LLDYR +M DE+K+NRMSCTV
Sbjct: 1142 DEQYKVLFDKILLEHCRKHKYLAKTGETFVKLVVRLMERLLDYRTIMHDENKENRMSCTV 1201
Query: 1206 NLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQT 1265
N+LNFYK+ REEMYIRYLYKL DLH +CDNYTEAAYTLLLH LLKWS++ C + + Q
Sbjct: 1202 NVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYTLLLHAKLLKWSEDVCVAHLTQR 1261
Query: 1266 GQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQ 1325
T QLKE LY+ II YFDKGKMWEEAI+L KELAEQYE E+FDYE LS+ L +Q
Sbjct: 1262 DGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAIALGKELAEQYENEMFDYEQLSELLKKQ 1321
Query: 1326 AKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQFPNA 1385
A+FYE+I+K++RPKPDYFAVGYYGQGFP+FLR KVFIYRGKEYERREDF+ +L+TQFPNA
Sbjct: 1322 AQFYENIVKVIRPKPDYFAVGYYGQGFPTFLRGKVFIYRGKEYERREDFEARLLTQFPNA 1381
Query: 1386 EKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYS 1445
EKM TTS PGDD+KN+PGQYIQCFTV+P LD P+F ++PV +QI++FY+ N VQRF YS
Sbjct: 1382 EKMKTTSPPGDDIKNSPGQYIQCFTVKPKLDLPPKF-HRPVSEQIVSFYRVNEVQRFEYS 1440
Query: 1446 RPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTA 1505
RP+R+G +P+NEFA+MWIERT + TAYKLPGILRWFEV + ISPLENAIETM
Sbjct: 1441 RPIRKGEKNPDNEFANMWIERTIYTTAYKLPGILRWFEVKSVFMVEISPLENAIETMQLT 1500
Query: 1506 NEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDK 1565
N+KI M+ Q+ D +LPINPLSMLLNGIVDPAVMGGFA YEKAFFT+ Y+++HPE +K
Sbjct: 1501 NDKINSMVQQHLDDPSLPINPLSMLLNGIVDPAVMGGFANYEKAFFTDRYLQEHPEAHEK 1560
Query: 1566 LTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMP-D 1624
+ LKDLIAWQIPFL GI+IH +V++ LRPFH+RME CFK LK KVEKEYGVR MP
Sbjct: 1561 IEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMEACFKQLKEKVEKEYGVRIMPSS 1620
Query: 1625 FDDRRVGRPRSMLRSY------RQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRV 1678
DDRR RPRSM+RS+ R +S+ S++S++SD STPS+P S+ F LE PK
Sbjct: 1621 LDDRRGSRPRSMVRSFTMPSSSRPLSVASVSSLSSD-STPSRPGSDGFALEPLLPKKMHS 1679
Query: 1679 EQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSRKHEFMSDT 1733
++ + E K ++ +KR + +F EK +D+ + +S+T
Sbjct: 1680 RSQDKLDKDDLEKEKKDKKKEKRNSKHQEIF--EKEFKPTDISLQQSEAVILSET 1732
>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
Length = 1870
Score = 1940 bits (5025), Expect = 0.0
Identities = 1009/1818 (55%), Positives = 1302/1818 (71%), Gaps = 54/1818 (2%)
Query: 1 MAPWRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFP 60
MA W ++++GVAIYN+ S +LSLQIGD V I E WYRGY +++K +GIFP
Sbjct: 1 MARWIPTKRQKYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIFP 60
Query: 61 KSFIHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSM 120
+++IH+KE TVE E +IP E+PL QE+T+TL EW IW++LYV +K F Q+Q M
Sbjct: 61 ETYIHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQM 120
Query: 121 MYDLMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSV 180
Y L+EWRSQ+LSGTLPKDEL ELK+KVT+KID+GN++L LDL+VRD++GNILDPD TS
Sbjct: 121 TYSLIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETST 180
Query: 181 ISLFHAHEEATDKITERIKEEMSKDQP-DYAMYSRISSSPTHSLYVFVRNFVCRIGEDAE 239
I+LF AHE A+ +I E+I+EE S Q D S S+ T+ LYV +NFVC IGEDAE
Sbjct: 181 IALFKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVCNIGEDAE 240
Query: 240 LFMSLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQI 299
LFM+LYDP++ T ISENYL+RWGS G PKEIE LNNL+ VFTDL + DL R ++ L+CQI
Sbjct: 241 LFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQI 300
Query: 300 VRVGKMDLKDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVT----- 354
VRVG M+LK+ KK T GLRRPFGVAVMDITDII GK + DEEKQHFIPF +
Sbjct: 301 VRVGHMELKE--GKKHTCGLRRPFGVAVMDITDIIHGKVD-DEEKQHFIPFQQIAMETYI 357
Query: 355 ----------------AENDFLHSLLGKVIASKG-DSGGQGLWVTMKMLVGDIIQIRKDY 397
EN+ L S+L KVIA+K + GQGLWV++K+L GD+ Q++K++
Sbjct: 358 RQRQLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNF 417
Query: 398 PHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDG 457
HLVDR+T +ARK+GFPEII+PGDVRNDIY+TL+ G+FDK K T +NVEV M V E+G
Sbjct: 418 SHLVDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEG 477
Query: 458 KTLPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSL 517
K L AI GAG + ++EY+SVVYYQVKQP W ETVKV++ IE++ R H+RF FRHRSS
Sbjct: 478 KLLEKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQ 537
Query: 518 ESKDKGEKNFAMSYVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVEN 577
E++DK E+ F +++VKLM DGTTL DG HDLVV KGD+KKMEDA YLTLP + +E
Sbjct: 538 ETRDKSERAFGVAFVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEE 597
Query: 578 KGATLSRSSSSVGGLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKL 637
K S++ + S++D F I+TL+CSTKLTQNV LLGLL WR Q ++ NL+KL
Sbjct: 598 KELQASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKL 657
Query: 638 KIVDGEEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLE 697
VDG E+VKFLQDTLDALFNIMME S S+ YD LVFDAL++II LI D KFQHFN VLE
Sbjct: 658 MEVDGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLE 717
Query: 698 AYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQL 757
YI +HFSATLAY KL VL Y+ + + E + LKAL+Y+F+FI++SR L+ +
Sbjct: 718 TYIYKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRF 777
Query: 758 Y-EGKEQMEFEESMRRLFESINNLMKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLS 816
Y + K+ EF S+R+LF + N LM + + ++ AALKY+PS+++DV++VFD LS
Sbjct: 778 YGQSKDGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYLPSIINDVKLVFDPVELS 837
Query: 817 QLLYEFYTCIPPVKLQKQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQ 876
L +F IP +L +QK+ M +IV+S LF++ ECR++LLP++T +L L+ +
Sbjct: 838 VLFCKFIQSIPDNQLVRQKLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQLDDNSNKP 897
Query: 877 HQVLERKYCVELLNSILEVLSYQDAAFTYHHIQEIMVQLLRTVNRTVITMGRDHILISHF 936
+ + +LL++ILEVL +D T HIQ IM +LLR +NRTVI M R I F
Sbjct: 898 ----DHEASSQLLSNILEVLDRKDVGATAVHIQLIMERLLRRINRTVIGMNRQSPHIGSF 953
Query: 937 VACMTAILNQMGDQHYSFYIETFQTSSELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQ 996
VACM A+L QM D HYS YI TF+T +++DFLMETFIMFKDLIGKNVY DWM M+M Q
Sbjct: 954 VACMIALLQQMDDSHYSHYISTFKTRQDIIDFLMETFIMFKDLIGKNVYAKDWMVMNMTQ 1013
Query: 997 NRVFLRAINKFAETMNQKFLEHTNFEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKIL 1056
NRVFLRAIN+FAE + + F++ +FE QLWNNYFHLAVAF+T +SLQLE FS AK NKI+
Sbjct: 1014 NRVFLRAINQFAEVLTRFFMDQASFELQLWNNYFHLAVAFLTHESLQLETFSQAKRNKIV 1073
Query: 1057 NKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEMTLIPEAELRKATIPIFFDMML 1116
KYGDMR+ IGF IRDMWY LG +KI FIP MVGPILE+TL PE ELRKATIPIFFDMM
Sbjct: 1074 KKYGDMRKEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVTLTPEVELRKATIPIFFDMMQ 1133
Query: 1117 CEYQRSGD--FKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENF 1174
CE+ SG+ F FENE+I KLD EVEGGRGDEQY LLE +L+E +H ++ S E F
Sbjct: 1134 CEFNFSGNGNFHMFENELITKLDQEVEGGRGDEQYKVLLEKLLLEHCRKHKYLSSSGEVF 1193
Query: 1175 VNLVKGLLEKLLDYRGV-MTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLD 1233
LV LLE LLDYR + M DESK+NRMSCTVN+LNFYK+ RE++YIRYLYKLRDLH D
Sbjct: 1194 ALLVSSLLENLLDYRTIIMQDESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLRDLHRD 1253
Query: 1234 CDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQLKETLYETIIGYFDKGKM 1293
C+NYTEAAYTLLLH LL+WSD+ C ++Q + T ++LKE LY+ II YFDKGKM
Sbjct: 1254 CENYTEAAYTLLLHAELLQWSDKPCVPHLLQKDSYYVYTQQELKEKLYQEIISYFDKGKM 1313
Query: 1294 WEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFP 1353
WE+AI L KELAE YE ++FDYE L L ++A FYE+I+K +RP+P+YFAVGYYGQGFP
Sbjct: 1314 WEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFYENIIKAMRPQPEYFAVGYYGQGFP 1373
Query: 1354 SFLRNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQP 1413
SFLRNK+FIYRGKEYERREDF ++L+TQFPNAEKM +T+ PG+D+K++P QY+QCFTV+P
Sbjct: 1374 SFLRNKIFIYRGKEYERREDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKP 1433
Query: 1414 VLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDPENEFASMWIERTSFVTAY 1473
V+ P +K+KPVP+QI+N+Y++N VQ+F YSRP R+G DP+NEFA+MWIERT++ TAY
Sbjct: 1434 VMSLPPSYKDKPVPEQILNYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAY 1493
Query: 1474 KLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNG 1533
PGIL+WFEV +S ISPLENAIETM NE+I + Q+ D +L ++PLSMLL+G
Sbjct: 1494 TFPGILKWFEVKQISTEEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSG 1553
Query: 1534 IVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSD 1593
IVDPAVMGGF+ YEKAFFTE+Y+++HPEDQ+K+ LK LIA Q+P L GI+IH +++++
Sbjct: 1554 IVDPAVMGGFSNYEKAFFTEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTE 1613
Query: 1594 NLRPFHDRMEECFKNLKMKVEKEYGVREM-PDFDDRRVGRPRSMLRSY------RQMSII 1646
L+P H+R+ CF+ LK KVEK YGV + P+ +R+ R S++ Y R++SI
Sbjct: 1614 QLKPLHERLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSIVLPYIMSSTLRRLSIT 1673
Query: 1647 SL------ASMNSDCSTPSKPTSESFDLE-LASPKTPRVEQEEPISPGSTLPEVKLRRSK 1699
S+ S NS + PS+P S+ LE L + + E +S E ++ + K
Sbjct: 1674 SVTSSVVSTSSNSSDNAPSRPGSDGSILEPLLERRASSGARVEDLSLREENSENRISKFK 1733
Query: 1700 KRTKRSSVVFADEKAAAESDLKRLSRKHE-----FMSDTNLSE-HAAIPLKASVLSQMSF 1753
++ S + A E DL +RK + + D LS H + P +++ LS
Sbjct: 1734 RKDWSLSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPL 1793
Query: 1754 ASQSMPTIPALALSVAGI 1771
++ T+ + +L GI
Sbjct: 1794 TPKATRTLSSPSLQTDGI 1811
>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
Length = 2030
Score = 1166 bits (3016), Expect = 0.0
Identities = 643/1659 (38%), Positives = 1004/1659 (60%), Gaps = 75/1659 (4%)
Query: 4 WRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFPKSF 63
W ++E++GV I +F+GS L L+IG+ V+I E C WYRG K ++GIFP ++
Sbjct: 2 WTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPANY 61
Query: 64 IHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSMMYD 123
IH+K+ V R E ++P E + EVT TL EW S+WKQLYV K + F +++ +M +
Sbjct: 62 IHLKKAIVSNRGQYETVVPLEDSIVTEVTATLQEWASLWKQLYVKHKVDLFYKLRHVMNE 121
Query: 124 LMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSVISL 183
L++ R QLLSG L +D+++E+K+ +T ++D+GN+ L LDL+ R +D ++D D SV L
Sbjct: 122 LIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPR-KDFEVVDSDQISVSDL 180
Query: 184 FHAHEEATDKITERIKEEMSKDQPDYAMYSRISSSPTHSLYVFVRNFVCR-IGEDAELFM 242
+ H + + ++ ++ +P + R+ H ++ +++F IGED ++F
Sbjct: 181 YKMHLSSRQSV-QQSTSQVDTMRPRHGETCRMPVP--HHFFLSLKSFTYNTIGEDTDVFF 237
Query: 243 SLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRV 302
SLYD + ISE +LVR G P+ E + + +FTDL +KD+ RD +Y++ ++R+
Sbjct: 238 SLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRD-LYIVAHVIRI 296
Query: 303 GKMDLKDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDF--L 360
G+M L D+ RRP+G AV+ I D+++ E EEK + + E+++ +
Sbjct: 297 GRMLLNDSKKGPPHLHYRRPYGCAVLSILDVLQSLTEVKEEKDFVLKVYTCNNESEWSQI 356
Query: 361 HSLLGKVIASK--GDSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIM 418
H + + ++K S GL +++++L GD+ QIR++ P + +R + RKLGFP++IM
Sbjct: 357 HENIIRKSSAKYSAPSASHGLIISLQLLRGDMEQIRRENPMIFNRGLAITRKLGFPDVIM 416
Query: 419 PGDVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRS 478
PGD+RND+Y+TL +GDF++ K+ Q+N+EV M V DG+ L + I +G+G+ + Y S
Sbjct: 417 PGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHS 476
Query: 479 VVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKN-FAMSYVKLMKE 537
V Y PRW E +K+ +PI+ + HLRF FRH S+ KDKGEK F ++ LM++
Sbjct: 477 FVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCST---KDKGEKKLFGFAFSTLMRD 533
Query: 538 DGTTLHDGFHDLVVLKGDSKK-MEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSS 596
DGTTL D H+L V K D + + YL LP + E+ + SS + S+
Sbjct: 534 DGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCK---EDYNGCPNIPSSLI--FQRST 588
Query: 597 RDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDAL 656
++ F IST + STKLTQNV LL LLKW+ P + + L +L+ V GEE+VKFLQD LD L
Sbjct: 589 KESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDVLGRLRHVSGEEIVKFLQDILDTL 648
Query: 657 FNIMMEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTV 716
F I+ ++++ +Y +LVF +L++II L+ D K+ HF V++ YIQ+HF+ LAYK+L+
Sbjct: 649 FVILDDNTE--KYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRC 706
Query: 717 LKTYLDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFES 776
LK Y+D S+ + + I ++ALEY+FKFIV+SR L+S+ G E+ +F S++ LF+S
Sbjct: 707 LKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQS 766
Query: 777 IN---NLMKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPV---- 829
I +L +T + Q A L P++ ++ +F + +++ + +P
Sbjct: 767 IRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIG 826
Query: 830 -KLQKQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVEL 888
+ K+QS+ V S LF E R ILLPV+ + L Q+ ++ C +
Sbjct: 827 QSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELL-------ICSGI 879
Query: 889 LNSILEVLSYQDAAFTYHHIQEIMVQ-LLRTVNRTVIT-MGRDHI--------------- 931
L SI ++ E+MV+ LL + +T++T M + H
Sbjct: 880 LGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAE 939
Query: 932 LISHFVACMTAILNQMGDQHYSFYIETFQTSSELVDFLMETFIMFKDLIGKNVYPGDWMA 991
+ +V+C+ ++L QM D H+ ++ FQ+ EL +FL++ F +F++L+ +V+P DWM
Sbjct: 940 ITGEYVSCLLSLLRQMCDTHFQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMV 999
Query: 992 MSMVQNRVFLRAINKFAETMNQKFLEHTNFEFQLWNNYFHLAVAFITQDSLQLEQFSHAK 1051
M ++ + + + + + +++ F E T+F+F++WN+YF LAV FI Q SLQLE + AK
Sbjct: 1000 MRLLTSNIIVTTVQYLSSALHKNFTE-TDFDFKVWNSYFSLAVLFINQPSLQLEIITSAK 1058
Query: 1052 YNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEMTLIPEAELRKATIPIF 1111
KIL+KYGDMR ++ + + MW LG++KI FIPGM+GP L +TL+P+ E+R IPIF
Sbjct: 1059 RKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIF 1118
Query: 1112 FDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSV 1171
DMM E +++G+FK+ E E+I KLD V G+GDE Y +L S+L + +P++ + V
Sbjct: 1119 HDMMDWEQRKNGNFKQVEAELIDKLDSMVSEGKGDESYRELF-SLLTQLFGPYPSLLEKV 1177
Query: 1172 E---------NFVNLVKGLLEKLLDYRGVMTDESKDNR-MSCTVNLLNFYKDN-NREEMY 1220
E +FV V L+E+LLDYR M E +N+ + CTVNL+NFYK N+EEMY
Sbjct: 1178 EQETWRETGISFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMY 1237
Query: 1221 IRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHP-QTHRQLKET 1279
IRY++KL D+HL +NYTEAA+TLLL+ LL+W D ++ +P QT Q KE
Sbjct: 1238 IRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRP-----LREFLHYPSQTEWQRKEG 1292
Query: 1280 LYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPK 1339
L II YF+KGK WE I LC+ELA QYE ++DY+ LS +A +Y++IM+ R +
Sbjct: 1293 LCRKIIHYFNKGKSWEFGIPLCRELACQYE-SLYDYQSLSWIRKMEASYYDNIMEQQRLE 1351
Query: 1340 PDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVK 1399
P++F VG+YG+ FP FLRNK ++ RG +YER E FQ +++++FP A M + P D +
Sbjct: 1352 PEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAIL 1411
Query: 1400 NAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDPENEF 1459
QY+Q + V P+ D + VPD++ +FY+ N V++F Y RP +G D ENEF
Sbjct: 1412 QCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEF 1471
Query: 1460 ASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSD 1519
S+WIERT+ + LPGI RWFEV +SPLENAI+ + N+++ +I+QYQ
Sbjct: 1472 KSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRSLISQYQHK 1531
Query: 1520 ETL-PINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIP 1578
+ IN LSM LNG++D AV GG A+Y++AFF ++Y+ HP D +K+T LK+L+ Q+
Sbjct: 1532 QVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYINKHPGDAEKITQLKELMQEQVH 1591
Query: 1579 FLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEY 1617
LG G+ +HEK V +RP H ++ + F+ ++ + E+
Sbjct: 1592 VLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEF 1630
>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
Length = 1966
Score = 1152 bits (2979), Expect = 0.0
Identities = 645/1633 (39%), Positives = 986/1633 (60%), Gaps = 76/1633 (4%)
Query: 4 WRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFPKSF 63
W + E++GV I +F+G+ LSL+IGD V+I E C WYRG+ +K+ ++GIFP S+
Sbjct: 2 WIPTEHEKYGVVIASFRGTVPYGLSLEIGDTVQILEKCDGWYRGFALKNPNIKGIFPSSY 61
Query: 64 IHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSMMYD 123
+H+K V+ + E +IP E + E+T+TL +WG++WKQLYV ++ + F ++ +M +
Sbjct: 62 VHLKNACVKNKGQFEMVIPTEDSVITEMTSTLRDWGTMWKQLYVRNEGDLFHRLWHIMNE 121
Query: 124 LMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSVISL 183
+++ R Q+L G L D +K++K+ +T+++D+GN+ L LDL+ R E ++DP++ S+ L
Sbjct: 122 ILDLRRQVLVGHLTHDRMKDVKRHITARLDWGNEQLGLDLVPRKEYA-MVDPEDISITEL 180
Query: 184 FHAHEEATDKITERIKEEMSKDQPDYAMYSRISSSPTHSLYVFVRNFVC-RIGEDAELFM 242
+ E K KD P A +H L+V +++ +C +GE+ E+
Sbjct: 181 YRLMEHRHRK----------KDTPVQAS--------SHHLFVQMKSLMCSNLGEELEVIF 222
Query: 243 SLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRV 302
SL+D + ISE + +R G PK + +F DLG+ +L +D IY+ I+R+
Sbjct: 223 SLFDSKENRPISERFFLRLNRNGLPKAPDKPERHCSLFVDLGSSELRKD-IYITVHIIRI 281
Query: 303 GKMDLKDTGAKK--CTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDF- 359
G+M G KK C+ RRPFG AV+ I D++ G+ + D + + E+++
Sbjct: 282 GRMG---AGEKKNACSVQYRRPFGCAVLSIADLLTGETKDDL----ILKVYMCNTESEWY 334
Query: 360 -LHSLLGKVIASKGDSGGQ--GLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEI 416
+H + K + ++ + G GL V++++L GDI QIR++Y + + RKLGF I
Sbjct: 335 QIHENIIKKLNARYNLTGSNAGLAVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNI 394
Query: 417 IMPGDVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEY 476
IMPG++RND+YIT+ +G+F+K K+ RNVEV M + G+TL + I G+G+ P +EY
Sbjct: 395 IMPGEMRNDLYITIERGEFEKGGKSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEY 454
Query: 477 RSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKN-FAMSYVKLM 535
S V Y PRW E +K+ +P++ + H+RF FRH S+ K+KGEK F S+V LM
Sbjct: 455 HSFVLYHNNSPRWSELLKLPIPVDKFRGAHIRFEFRHCST---KEKGEKKLFGFSFVPLM 511
Query: 536 KEDGTTLHDGFHDLVVLK-GDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSV 594
+EDG TL DG H+L+V K ++ ++D + YL LP +KG L ++ ++
Sbjct: 512 QEDGRTLPDGTHELIVHKCEENTNLQDTTRYLKLPF------SKGIFLGNNNQAMK---- 561
Query: 595 SSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLD 654
++++ F I++ +CSTKLTQN +L LLKWR P + L KLK +DG E+VKFLQDTLD
Sbjct: 562 ATKESFCITSFLCSTKLTQNGDMLDLLKWRTHPDKITGCLSKLKEIDGSEIVKFLQDTLD 621
Query: 655 ALFNIMMEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLM 714
LF I+ E+SQ +Y VFD+L++II L+ D KF HF V++ YI+ HF+ LAY+ L+
Sbjct: 622 TLFGILDENSQ--KYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLI 679
Query: 715 TVLKTYLDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLF 774
VLK Y+D + E+ E I LKA EY+FK+IV+SR LFS G+ + EF ++ L
Sbjct: 680 KVLKWYVDRITEAERQEHIQEVLKAQEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELL 739
Query: 775 ESINNLMKSQYKTTILL---QVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPV-- 829
S+ + + K + L Q L P+V ++ +FD + ++ L+ + +P +
Sbjct: 740 MSVRFFLSQESKGSGALSQSQAVFLSSFPAVYSELLKLFDVREVANLVQDTLGSLPTILH 799
Query: 830 ---KLQKQKVQSMNEIVQSNLFKKQECRDILLPVITKELK-ELLEQKD-DMQHQVLERKY 884
LQ K+Q + + V+S L+ + R ILLPV+ L L EQKD M ++L +
Sbjct: 800 VDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHIHLQEQKDLIMCARILSNVF 859
Query: 885 CVELLNS----ILEVLSYQDAAFTYHHIQEIMVQLLRTVNRTVITMGRDHILISHFVACM 940
C+ NS +LE + A+ ++ I+ R + + + FVAC+
Sbjct: 860 CLIKKNSSEKSVLEEIDVIVASLLDILLRTILEITSRPQPSSSAMRFQFQDVTGEFVACL 919
Query: 941 TAILNQMGDQHYSFYIETFQTSSELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVF 1000
++L QM D+HY +++F T EL DFL++ F +F+ LI ++P DW M +V N V
Sbjct: 920 LSLLRQMTDRHYQQLLDSFNTKEELRDFLLQIFTVFRILIRPEMFPKDWTVMRLVANNVI 979
Query: 1001 LRAINKFAETMNQKFLEHTNFEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYG 1060
+ + ++ + + FL NF++++W++YF+LAV FI Q LQLE F+ +K K+L KYG
Sbjct: 980 ITTVLYLSDALRKNFLNE-NFDYKIWDSYFYLAVIFINQLCLQLEMFTPSKKKKVLEKYG 1038
Query: 1061 DMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQ 1120
DMR +G I MW LG++K+ FIP ++GP LE+TLIP+ +LR IPIF DMM E +
Sbjct: 1039 DMRVTMGCEIFSMWQNLGEHKLHFIPALIGPFLEVTLIPQPDLRNVMIPIFHDMMDWEQR 1098
Query: 1121 RSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKG 1180
RSG+FK+ E ++I KLD + G+GDE Y +L SIL++ E T +S + + V
Sbjct: 1099 RSGNFKQVEAKLIDKLDSLMSEGKGDETYRELFNSILLK-KIERETWRESGVSLIATVTR 1157
Query: 1181 LLEKLLDYRGVMT-DESKDNRMSCTVNLLNFYKDN-NREEMYIRYLYKLRDLHLDCDNYT 1238
L+E+LLDYR M E ++ CTV+LLNFYK N+EEMYIRY++KL DLHL N+T
Sbjct: 1158 LMERLLDYRDCMKMGEVDGKKIGCTVSLLNFYKTELNKEEMYIRYIHKLYDLHLKAQNFT 1217
Query: 1239 EAAYTLLLHTWLLKWSDEQCASQVMQTGQQHP-QTHRQLKETLYETIIGYFDKGKMWEEA 1297
EAAYTLLL+ LL+WSD ++ +P QT Q KE L+ TII FD+GK WE
Sbjct: 1218 EAAYTLLLYDELLEWSDRP-----LREFLTYPMQTEWQRKEHLHLTIIQNFDRGKCWENG 1272
Query: 1298 ISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLR 1357
I LC+++AEQYE +DY LS+ + +A Y+ IM R +P++F VG+YG+ FP FLR
Sbjct: 1273 IILCRKIAEQYE-SYYDYRNLSKMRMMEASLYDKIMDQQRLEPEFFRVGFYGKKFPFFLR 1331
Query: 1358 NKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDE 1417
NK F+ RG +YER E FQ +++ +FP+A M + P + + A QY+Q + V P+ +
Sbjct: 1332 NKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPDETIFQAEAQYLQIYAVTPIPES 1391
Query: 1418 HPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPG 1477
+ + VPD I +FYK N++ +F Y RP +GT D ENEF S+W+ERTS LPG
Sbjct: 1392 QEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGTKDKENEFKSLWVERTSLYLVQSLPG 1451
Query: 1478 ILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDP 1537
I RWFEV +SPLENAIE + N+++ +I+Q Q+ + INPL+M LNG++D
Sbjct: 1452 ISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQMQNINPLTMCLNGVIDA 1511
Query: 1538 AVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRP 1597
AV GG ++Y++AFF +EY+ HPED +K+ L++L+ Q L G+ +HEK V ++RP
Sbjct: 1512 AVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQILEFGLAVHEKFVPQDMRP 1571
Query: 1598 FHDRMEECFKNLK 1610
H ++ + F +K
Sbjct: 1572 LHKKLVDQFFVMK 1584
>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
Length = 2186
Score = 82.0 bits (201), Expect = 5e-15
Identities = 74/347 (21%), Positives = 145/347 (41%), Gaps = 13/347 (3%)
Query: 1267 QQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQA 1326
Q P L E LY + + K + +E + K + +E + D++ LS
Sbjct: 1800 QDTPYNENILVEQLY-MCVEFLWKSERYELIADVNKPIIAVFEKQR-DFKKLSDLYYDIH 1857
Query: 1327 KFYESIMKILRPKPD----YFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQF 1382
+ Y + +++ + Y+ V +YGQGF K +IY+ + + +L+ +
Sbjct: 1858 RSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLY 1917
Query: 1383 PNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRF 1442
+ + D K P + V P F+ K + D+ +F + + RF
Sbjct: 1918 ADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRF 1977
Query: 1443 HYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETM 1502
+ P A RT T++ P + + +V+ S T ++P+E AI+ M
Sbjct: 1978 VFETPFTLSG-KKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEM 2036
Query: 1503 STANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPED 1562
S K + +NQ + E + + L + L G V V G Y +AF E + +P++
Sbjct: 2037 S----KKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDN 2092
Query: 1563 QDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNL 1609
Q KL LK++ G + ++E+ + ++ + + + +K++
Sbjct: 2093 QVKL--LKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDM 2137
Score = 35.8 bits (81), Expect = 0.39
Identities = 58/297 (19%), Positives = 116/297 (39%), Gaps = 53/297 (17%)
Query: 423 RNDIYITLLQGDFDK---YNKTTQRNVEVIMCVCAEDGKTLPNAICV-GAGDKPM---NE 475
+N IYI +D +NK RN+ V + D ++ C+ G P+
Sbjct: 672 KNQIYIYPKHLKYDSQKCFNKA--RNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAA 729
Query: 476 YRSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFA 528
Y +V+++ + P + + VK+ +P + ++ H+ F F H +++ + K+ E +
Sbjct: 730 YTAVLHHS-QNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVG 788
Query: 529 MSYVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSS 588
+++ LMK D + AS +P N + +S
Sbjct: 789 YAWLPLMKHD---------------------QIASQEYNIPIATSLPPNYLSFQDSASGK 827
Query: 589 VGGLSV----SSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQ----------LLQENL 634
GG + + +F +ST V ST TQ+ + + K + ++
Sbjct: 828 HGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCK 887
Query: 635 EKLKIVDGEEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIADRKFQH 691
L + ++ FL L+ LF ++++ ++ DE V L I+ + + H
Sbjct: 888 NLLNVEKIHAIMSFLPIILNQLFKVLVQ-NEEDEITTTVTRVLTDIVAKCHEEQLDH 943
>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
Length = 2068
Score = 65.5 bits (158), Expect = 5e-10
Identities = 75/384 (19%), Positives = 153/384 (39%), Gaps = 37/384 (9%)
Query: 1255 DEQCASQVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFD 1314
DE+ AS + G Q + + L E K + +E + K + YE D
Sbjct: 1692 DEE-ASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRR-D 1749
Query: 1315 YELLSQNLIQQAKFYESIMKIL----RPKPDYFAVGYYGQ--------------GFPSFL 1356
+E L+ + Y + +++ R YF V ++GQ GF
Sbjct: 1750 FERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDE 1809
Query: 1357 RNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLD 1416
K +IY+ + + +L+ + + D K P + V
Sbjct: 1810 DGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTH 1869
Query: 1417 EHPRFKNKPVPDQIINFYKSNYVQRFHYSRPV-----RRGTVDPENEFASMWIERTSFVT 1471
P F K + ++ F +S+ ++RF + P R+G V+ + + RT
Sbjct: 1870 VIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCK------RRTILTA 1923
Query: 1472 AYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLL 1531
+ P + + V++ T ++P+E AI+ MS K + + Q S + + L + L
Sbjct: 1924 IHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMS----KKVAELRQLCSSAEVDMIKLQLKL 1979
Query: 1532 NGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRV 1591
G V V G Y +AF + + +P+++ KL LK++ + G + ++E+ +
Sbjct: 1980 QGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKL--LKEVFRQFVEACGQALAVNERLI 2037
Query: 1592 SDNLRPFHDRMEECFKNLKMKVEK 1615
++ + + M+ ++ + ++ +
Sbjct: 2038 KEDQLEYQEEMKANYREMAKELSE 2061
Score = 39.3 bits (90), Expect = 0.036
Identities = 67/332 (20%), Positives = 130/332 (39%), Gaps = 54/332 (16%)
Query: 478 SVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFAMS 530
+ V + + P + + +K+ +P + ++ HL F H + S + +D E S
Sbjct: 698 AAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYS 757
Query: 531 YVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVG 590
++ L+K DG + H V S + Y L RH+ V
Sbjct: 758 WLPLLK-DGRVVTSEQHIPVSANLPSGYL----GYQELGMGRHY--------GPEIKWVD 804
Query: 591 GLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQL--------LQENLEKLKIVDG 642
G + + IST + ST TQ+ L ++ K + L + L+ L ++G
Sbjct: 805 G----GKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEG 860
Query: 643 EEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIAD-------RKFQHFNTV 695
++ FL L+ LF ++ +Q +E + V +I+++ + R + +
Sbjct: 861 HVMIAFLPTILNQLFRVLTRATQ-EEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 919
Query: 696 LEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYV-FKFIVRSRTLF 754
E Y+ + +++L + T L S+ L + K L+Y F F V +++
Sbjct: 920 AEPYVASEYKT--VHEELTKSMTTILKPSA------DFLTSNKLLKYSWFFFDVLIKSMA 971
Query: 755 SQLYEGKE-----QMEFEESMRRLFESINNLM 781
L E + F S E++ N++
Sbjct: 972 QHLIENSKVKLLRNQRFPASYHHAVETVVNML 1003
>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
Length = 2069
Score = 65.5 bits (158), Expect = 5e-10
Identities = 75/384 (19%), Positives = 153/384 (39%), Gaps = 37/384 (9%)
Query: 1255 DEQCASQVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFD 1314
DE+ AS + G Q + + L E K + +E + K + YE D
Sbjct: 1693 DEE-ASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRR-D 1750
Query: 1315 YELLSQNLIQQAKFYESIMKIL----RPKPDYFAVGYYGQ--------------GFPSFL 1356
+E L+ + Y + +++ R YF V ++GQ GF
Sbjct: 1751 FERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDE 1810
Query: 1357 RNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLD 1416
K +IY+ + + +L+ + + D K P + V
Sbjct: 1811 DGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTH 1870
Query: 1417 EHPRFKNKPVPDQIINFYKSNYVQRFHYSRPV-----RRGTVDPENEFASMWIERTSFVT 1471
P F K + ++ F +S+ ++RF + P R+G V+ + + RT
Sbjct: 1871 VIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCK------RRTILTA 1924
Query: 1472 AYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLL 1531
+ P + + V++ T ++P+E AI+ MS K + + Q S + + L + L
Sbjct: 1925 IHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMS----KKVAELRQLCSSAEVDMIKLQLKL 1980
Query: 1532 NGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRV 1591
G V V G Y +AF + + +P+++ KL LK++ + G + ++E+ +
Sbjct: 1981 QGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKL--LKEVFRQFVEACGQALAVNERLI 2038
Query: 1592 SDNLRPFHDRMEECFKNLKMKVEK 1615
++ + + M+ ++ + ++ +
Sbjct: 2039 KEDQLEYQEEMKANYREMAKELSE 2062
Score = 39.3 bits (90), Expect = 0.036
Identities = 67/332 (20%), Positives = 130/332 (39%), Gaps = 54/332 (16%)
Query: 478 SVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFAMS 530
+ V + + P + + +K+ +P + ++ HL F H + S + +D E S
Sbjct: 699 AAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYS 758
Query: 531 YVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVG 590
++ L+K DG + H V S + Y L RH+ V
Sbjct: 759 WLPLLK-DGRVVTSEQHIPVSANLPSGYL----GYQELGMGRHY--------GPEIKWVD 805
Query: 591 GLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQL--------LQENLEKLKIVDG 642
G + + IST + ST TQ+ L ++ K + L + L+ L ++G
Sbjct: 806 G----GKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEG 861
Query: 643 EEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIAD-------RKFQHFNTV 695
++ FL L+ LF ++ +Q +E + V +I+++ + R + +
Sbjct: 862 HVMIAFLPTILNQLFRVLTRATQ-EEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 920
Query: 696 LEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYV-FKFIVRSRTLF 754
E Y+ + +++L + T L S+ L + K L+Y F F V +++
Sbjct: 921 AEPYVASEYKT--VHEELTKSMTTILKPSA------DFLTSNKLLKYSWFFFDVLIKSMA 972
Query: 755 SQLYEGKE-----QMEFEESMRRLFESINNLM 781
L E + F S E++ N++
Sbjct: 973 QHLIENSKVKLLRNQRFPASYHHAVETVVNML 1004
>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
Length = 2099
Score = 63.5 bits (153), Expect = 2e-09
Identities = 68/280 (24%), Positives = 117/280 (41%), Gaps = 30/280 (10%)
Query: 1342 YFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMT---QFPNAEKMNTT--SAPGD 1396
YF VG++G F L + F+Y+ + + +L Q AE + S P D
Sbjct: 1794 YFRVGFFGSKFGD-LDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVD 1852
Query: 1397 DVKNAPGQ-YIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVD- 1454
K P + YIQ V+P DE+ + D++ F K+ ++RF Y+ P T++
Sbjct: 1853 KTKLDPNKAYIQITFVEPYFDEYE------MKDRVTYFEKNFNLRRFMYTTPF---TLEG 1903
Query: 1455 -PENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMI 1513
P E + T T + P I V+ + ++P+E AIE M ++ + I
Sbjct: 1904 RPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAI 1963
Query: 1514 NQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLI 1573
NQ D + L M+L G V V G + + F E P D H L
Sbjct: 1964 NQEPPDAKM----LQMVLQGSVGATVNQGPLEVAQVFLAE-----IPADPKLYRHHNKLR 2014
Query: 1574 AWQIPFL---GAGIKIHEKRVSDNLRPFHDRMEECFKNLK 1610
F+ G ++ +++ ++ + R + +++ + LK
Sbjct: 2015 LCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLK 2054
Score = 40.0 bits (92), Expect = 0.021
Identities = 81/340 (23%), Positives = 136/340 (40%), Gaps = 48/340 (14%)
Query: 398 PHLVDRTTVVARKLGFP--EIIMPGDV-RNDIYITLLQGDFDKYNK-TTQRNVEV-IMCV 452
P +RT L FP E+ +P V RN +Y+ + +F NK + RN+ + I +
Sbjct: 532 PFPENRTRPHKEILEFPTREVYVPHTVYRNLLYVYPQRLNF--VNKLASARNITIKIQFM 589
Query: 453 CAEDGKT-LPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMF 511
C ED +P +G + + E + V Y K P + E VK+ +P + HL F F
Sbjct: 590 CGEDASNAMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTF 649
Query: 512 RHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSY 571
H S + K + Y L L G + L V +K+ P+Y
Sbjct: 650 YH-ISCQQKQGASVETLLGYSWLPILLNERLQTGSYCLPVA---LEKLP--------PNY 697
Query: 572 RHHVENK----GATLSRSSSSVGGLSVSSRDVFSIST---------LVCSTKLTQNVGLL 618
H K + + G ++ + V S+ T +C + +Q +
Sbjct: 698 SMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPI 757
Query: 619 GLLKWRMKPQLLQENLEKLKIV-----DGEEVVKFLQDTLDALFNI----MMEHSQSDEY 669
+L ++ L+ L KL I+ E +V FL LD LF + M+ Q+ +
Sbjct: 758 RVLDQKISEMALEHEL-KLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANF 816
Query: 670 DILVFDALIYIIGLIAD----RKFQH-FNTVLEAYIQQHF 704
F++++ I + + K QH N +L +Y+ F
Sbjct: 817 SQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVF 856
>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
Length = 2073
Score = 59.3 bits (142), Expect = 3e-08
Identities = 67/346 (19%), Positives = 145/346 (41%), Gaps = 29/346 (8%)
Query: 1276 LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKI 1335
L E L + + G + K + +E + K + YE ++E L+Q Y I+++
Sbjct: 1695 LLELLEQCVDGLW-KAERYEIISEISKLIVPIYEKRR-EFEKLTQVYRTLHGAYTKILEV 1752
Query: 1336 LRPKP----DYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTT 1391
+ K +F V +YGQ F K +IY+ + + ++L+ + EK T
Sbjct: 1753 MHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLY--GEKFGTE 1810
Query: 1392 SAP---GDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPV 1448
+ D NA + +Q V P F +K + ++ F +++ + RF + P
Sbjct: 1811 NVKIIQDSDKVNAKELDPKYAHIQ-VTYVKPYFDDKELTERKTEFERNHNISRFVFEAPY 1869
Query: 1449 -----RRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMS 1503
++G ++ + + RT T+ P + + + Q + P++ A + +
Sbjct: 1870 TLSGKKQGCIEEQCK------RRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIK 1923
Query: 1504 TANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQ 1563
++ + + D + L + L G V V G Y +AF + +P
Sbjct: 1924 DKTAELQKLCSSTDVD----MIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPK- 1978
Query: 1564 DKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNL 1609
K++ LKD+ I ++++E+ + ++ +H+ ++ F+++
Sbjct: 1979 -KVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDM 2023
Score = 37.4 bits (85), Expect = 0.14
Identities = 84/362 (23%), Positives = 145/362 (40%), Gaps = 56/362 (15%)
Query: 423 RNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPM------NEY 476
+N +Y+ LQ +D KT + + +CV D + KP N Y
Sbjct: 640 KNHLYVYPLQLKYDS-QKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAY 698
Query: 477 RSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMK 536
+VV + + P + + +K+ +PI Q+ HL F F H S E KG K
Sbjct: 699 -AVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYH-VSCEINTKGTTK---------K 747
Query: 537 EDGTTLHDGFHDLVVLKGDS----KKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGL 592
+D GF + +LK ++ SA L P Y N SR +V
Sbjct: 748 QDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLP-PGYL----NLNDAESRRQCNVDIK 802
Query: 593 SV-SSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQLLQ--------ENLEKLKIVDGE 643
V ++ + I + + ST TQ+ L + K+ QL+Q E ++ LK +
Sbjct: 803 WVDGAKPLLKIKSHLESTIYTQD---LHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAM 859
Query: 644 EV---VKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYI 700
E+ ++FL L LF ++ + D+ I L++I+ + + ++ L ++I
Sbjct: 860 EIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHE---EGLDSYLRSFI 916
Query: 701 QQHF--------SATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYVFKFIVRSRT 752
+ F A L ++ L T + L S+ I + LK + F+ I +S
Sbjct: 917 KYSFRPEKPSAPQAQLIHETLATTMIAILKQSA---DFLSINKLLKYSWFFFEIIAKSMA 973
Query: 753 LF 754
+
Sbjct: 974 TY 975
>gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]
Length = 2047
Score = 58.5 bits (140), Expect = 6e-08
Identities = 74/304 (24%), Positives = 116/304 (38%), Gaps = 38/304 (12%)
Query: 1280 LYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPK 1339
L E GYF G ++E + K L E DY+ L+ K E+ KI+
Sbjct: 1686 LLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHR-DYKKLAA---VHGKLQEAFTKIMHQS 1741
Query: 1340 PD-------YFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQFP-----NAEK 1387
YF VG+YG F L + F+Y+ + + +L + + +
Sbjct: 1742 SGWERVFGTYFRVGFYGAHFGD-LDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVE 1800
Query: 1388 MNTTSAPGDDVK-NAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSR 1446
+ S P D K ++ YIQ V+P D + + D++ F ++ ++ F +
Sbjct: 1801 IIKDSNPVDKSKLDSQKAYIQITYVEPYFDTYE------LKDRVTYFDRNYGLRTFLFCT 1854
Query: 1447 PVRRGTVD--PENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMST 1504
P T D E +T T + P I V H +T ++P+E AIE M
Sbjct: 1855 PF---TPDGRAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQK 1911
Query: 1505 ANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHPEDQD 1564
++ Q D + L M+L G V P V G + + F E PED
Sbjct: 1912 KTRELAFATEQDPPDAKM----LQMVLQGSVGPTVNQGPLEVAQVFLAE-----IPEDPK 1962
Query: 1565 KLTH 1568
H
Sbjct: 1963 LFRH 1966
>gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]
Length = 2109
Score = 58.2 bits (139), Expect = 7e-08
Identities = 56/220 (25%), Positives = 94/220 (42%), Gaps = 22/220 (10%)
Query: 1342 YFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMTQF-----PNAEKMNTTSAPGD 1396
YF VG+YG F L + F+Y+ + + +L + + ++ S P D
Sbjct: 1811 YFRVGFYGTKFGD-LDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIKDSNPVD 1869
Query: 1397 DVKNAPGQ-YIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVD- 1454
K P + YIQ V+P D + + D+I F K+ ++RF Y P T+D
Sbjct: 1870 KCKLDPNKAYIQITYVEPYFDTYE------MKDRITYFDKNYNLRRFMYCTPF---TLDG 1920
Query: 1455 -PENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMI 1513
E + +T T++ P I V H + ++P+E AIE M +++
Sbjct: 1921 RAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFAT 1980
Query: 1514 NQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTE 1553
+Q +D + L M+L G V V G + + F +E
Sbjct: 1981 HQDPADPKM----LQMVLQGSVGTTVNQGPLEVAQVFLSE 2016
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 42.4 bits (98), Expect = 0.004
Identities = 45/180 (25%), Positives = 81/180 (45%), Gaps = 11/180 (6%)
Query: 1139 EVEGGRGDEQY-MQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKLLDYRGVMTDESK 1197
EVE + + + M+ LE + M+ AAE P K+ +F + LLE E +
Sbjct: 1113 EVEQKKNEYNFKMRQLEHV-MDSAAEDPQSPKTPPHFQTHLAKLLE-------TQEQEIE 1164
Query: 1198 DNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQ 1257
D R S T K N E+ + ++++ + +N + L+ WLL+ +
Sbjct: 1165 DGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDD 1224
Query: 1258 CASQVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYEL 1317
Q + Q HP ++QLK E+I K K+ EE + + +L E+ + +++ E+
Sbjct: 1225 IKRQKENSDQNHPD-NQQLKNEQEESIKERLAKSKIVEEMLKMKADL-EEVQSALYNKEM 1282
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 40.4 bits (93), Expect = 0.016
Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Query: 9 KERHGVAIYNFQGSGAPQLSLQIGDVV-RIQETCGDWYRGYLIKHKMLQGIFPKSFIHIK 67
K R A+Y+F+G +LS + GD++ ++ DW G L+ GIFPK++I
Sbjct: 672 KGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGK---SGIFPKNYIQFL 728
Query: 68 EVT 70
+++
Sbjct: 729 QIS 731
Score = 32.3 bits (72), Expect = 4.3
Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 12 HGVAIYNFQGSGAPQLSLQIGDVVRIQETCG-DWYRGYLIKHKMLQGIFPKSFIHI 66
H V +++F L+L G++V + E DWYRG + GIFP +++ +
Sbjct: 440 HAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRG---NCRNQIGIFPANYVKV 492
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 40.4 bits (93), Expect = 0.016
Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Query: 9 KERHGVAIYNFQGSGAPQLSLQIGDVV-RIQETCGDWYRGYLIKHKMLQGIFPKSFIHIK 67
K R A+Y+F+G +LS + GD++ ++ DW G L+ GIFPK++I
Sbjct: 708 KGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGK---SGIFPKNYIQFL 764
Query: 68 EVT 70
+++
Sbjct: 765 QIS 767
Score = 32.3 bits (72), Expect = 4.3
Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 12 HGVAIYNFQGSGAPQLSLQIGDVVRIQETCG-DWYRGYLIKHKMLQGIFPKSFIHI 66
H V +++F L+L G++V + E DWYRG + GIFP +++ +
Sbjct: 476 HAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRG---NCRNQIGIFPANYVKV 528
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 40.4 bits (93), Expect = 0.016
Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Query: 9 KERHGVAIYNFQGSGAPQLSLQIGDVV-RIQETCGDWYRGYLIKHKMLQGIFPKSFIHIK 67
K R A+Y+F+G +LS + GD++ ++ DW G L+ GIFPK++I
Sbjct: 731 KGRKAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGK---SGIFPKNYIQFL 787
Query: 68 EVT 70
+++
Sbjct: 788 QIS 790
Score = 32.3 bits (72), Expect = 4.3
Identities = 17/56 (30%), Positives = 29/56 (51%), Gaps = 4/56 (7%)
Query: 12 HGVAIYNFQGSGAPQLSLQIGDVVRIQETCG-DWYRGYLIKHKMLQGIFPKSFIHI 66
H V +++F L+L G++V + E DWYRG + GIFP +++ +
Sbjct: 499 HAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRG---NCRNQIGIFPANYVKV 551
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 39.7 bits (91), Expect = 0.027
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 7/85 (8%)
Query: 12 HGVAIYNFQGSGAPQLSLQIGDVVRIQETCGD-WYRGYLIKHKMLQGIFPKSFIHIKEVT 70
+GVA+Y FQ +L ++GD +RI T D W G L K GIFP F+ ++
Sbjct: 247 YGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSL---KGRTGIFPYRFV---KLC 300
Query: 71 VEKRRNTENIIPAEIPLAQEVTTTL 95
+ R +P E LA+ T+L
Sbjct: 301 PDTRVEETMALPQEGSLARIPETSL 325
>gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]
Length = 1253
Score = 39.3 bits (90), Expect = 0.036
Identities = 67/332 (20%), Positives = 130/332 (39%), Gaps = 54/332 (16%)
Query: 478 SVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFAMS 530
+ V + + P + + +K+ +P + ++ HL F H + S + +D E S
Sbjct: 698 AAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYS 757
Query: 531 YVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVG 590
++ L+K DG + H V S + Y L RH+ V
Sbjct: 758 WLPLLK-DGRVVTSEQHIPVSANLPSGYL----GYQELGMGRHY--------GPEIKWVD 804
Query: 591 GLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQL--------LQENLEKLKIVDG 642
G + + IST + ST TQ+ L ++ K + L + L+ L ++G
Sbjct: 805 G----GKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEG 860
Query: 643 EEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIAD-------RKFQHFNTV 695
++ FL L+ LF ++ +Q +E + V +I+++ + R + +
Sbjct: 861 HVMIAFLPTILNQLFRVLTRATQ-EEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 919
Query: 696 LEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYV-FKFIVRSRTLF 754
E Y+ + +++L + T L S+ L + K L+Y F F V +++
Sbjct: 920 AEPYVASEYKT--VHEELTKSMTTILKPSA------DFLTSNKLLKYSWFFFDVLIKSMA 971
Query: 755 SQLYEGKE-----QMEFEESMRRLFESINNLM 781
L E + F S E++ N++
Sbjct: 972 QHLIENSKVKLLRNQRFPASYHHAVETVVNML 1003
>gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]
Length = 1254
Score = 39.3 bits (90), Expect = 0.036
Identities = 67/332 (20%), Positives = 130/332 (39%), Gaps = 54/332 (16%)
Query: 478 SVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRH-------RSSLESKDKGEKNFAMS 530
+ V + + P + + +K+ +P + ++ HL F H + S + +D E S
Sbjct: 699 AAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYS 758
Query: 531 YVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVG 590
++ L+K DG + H V S + Y L RH+ V
Sbjct: 759 WLPLLK-DGRVVTSEQHIPVSANLPSGYL----GYQELGMGRHY--------GPEIKWVD 805
Query: 591 GLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQL--------LQENLEKLKIVDG 642
G + + IST + ST TQ+ L ++ K + L + L+ L ++G
Sbjct: 806 G----GKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEG 861
Query: 643 EEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIAD-------RKFQHFNTV 695
++ FL L+ LF ++ +Q +E + V +I+++ + R + +
Sbjct: 862 HVMIAFLPTILNQLFRVLTRATQ-EEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYK 920
Query: 696 LEAYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYV-FKFIVRSRTLF 754
E Y+ + +++L + T L S+ L + K L+Y F F V +++
Sbjct: 921 AEPYVASEYKT--VHEELTKSMTTILKPSA------DFLTSNKLLKYSWFFFDVLIKSMA 972
Query: 755 SQLYEGKE-----QMEFEESMRRLFESINNLM 781
L E + F S E++ N++
Sbjct: 973 QHLIENSKVKLLRNQRFPASYHHAVETVVNML 1004
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 38.5 bits (88), Expect = 0.061
Identities = 16/55 (29%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 14 VAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFPKSFIHIKE 68
+A+Y ++ S L+ Q GDV+ + + GDW+ G + G+FP +++ +K+
Sbjct: 1008 IAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDK---AGVFPSNYVRLKD 1059
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 38.5 bits (88), Expect = 0.061
Identities = 16/55 (29%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 14 VAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFPKSFIHIKE 68
+A+Y ++ S L+ Q GDV+ + + GDW+ G + G+FP +++ +K+
Sbjct: 1008 IAMYTYESSEQGDLTFQQGDVILVTKKDGDWWTGTVGDK---AGVFPSNYVRLKD 1059
>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
Length = 882
Score = 38.5 bits (88), Expect = 0.061
Identities = 22/84 (26%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 14 VAIYNFQGSGAPQLSLQIGDVVRIQETCGD-WYRGYLIKHKMLQGIFPKSFI-HIKEVTV 71
+A+Y ++ + +L L G++ R+ E C D W++G ++ + G+FP +++ + V
Sbjct: 470 LALYAYKPQKSDELELHKGEMYRVLEKCQDGWFKGASLR-TGVSGVFPGNYVTPVSRVPA 528
Query: 72 EKRRNTENIIPAEIPLAQEVTTTL 95
N + PLA+ +TTT+
Sbjct: 529 GGAGPPRNNVVGGSPLAKGITTTM 552
>gi|7662184 zinc finger homeobox 1b [Homo sapiens]
Length = 1214
Score = 37.7 bits (86), Expect = 0.10
Identities = 47/226 (20%), Positives = 89/226 (39%), Gaps = 41/226 (18%)
Query: 1584 IKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEY-GVREMPDFDDRRVGRPRSMLRSYRQ 1642
+K + S ++ H+ + C L++ + ++ + D R P +
Sbjct: 733 VKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPL-----N 787
Query: 1643 MSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRT 1702
+S S + +S TP+ +SE E P+ + +EP S +T K +T
Sbjct: 788 LSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPK-QMKEPKSIIAT---------KNKT 837
Query: 1703 KRSSVVFADEKAAAESD-----LKRLSRKHEFMSDTNLSEHAAIPLKASVLSQMSFASQS 1757
K SS+ ++ S+ L K EF + NL + P V S F+++
Sbjct: 838 KASSISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNP----VFSMNPFSAKP 893
Query: 1758 MPT-------------IPALALSVAGI---PGLDEANTSPRLSQTF 1787
+ T +P + S+ G+ PGLD+ + P ++ T+
Sbjct: 894 LYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTY 939
>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
Length = 1015
Score = 37.0 bits (84), Expect = 0.18
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 833 KQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDD--MQHQVLERKYCVELLN 890
K+K+ + E + K Q + L KEL++L+ QKDD + H+ L +K +++ +
Sbjct: 267 KEKIDQLQEELLHTQLKYQRILE-RLEKENKELRKLVLQKDDKGIHHRKL-KKSLIDMYS 324
Query: 891 SILEVLSYQDAAF-TYHHIQEIMV 913
+L+VLS DA++ T H+ ++V
Sbjct: 325 EVLDVLSDYDASYNTQDHLPRVVV 348
>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
Length = 997
Score = 37.0 bits (84), Expect = 0.18
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 833 KQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDD--MQHQVLERKYCVELLN 890
K+K+ + E + K Q + L KEL++L+ QKDD + H+ L +K +++ +
Sbjct: 249 KEKIDQLQEELLHTQLKYQRILE-RLEKENKELRKLVLQKDDKGIHHRKL-KKSLIDMYS 306
Query: 891 SILEVLSYQDAAF-TYHHIQEIMV 913
+L+VLS DA++ T H+ ++V
Sbjct: 307 EVLDVLSDYDASYNTQDHLPRVVV 330
>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
Length = 979
Score = 37.0 bits (84), Expect = 0.18
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 833 KQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDD--MQHQVLERKYCVELLN 890
K+K+ + E + K Q + L KEL++L+ QKDD + H+ L +K +++ +
Sbjct: 231 KEKIDQLQEELLHTQLKYQRILE-RLEKENKELRKLVLQKDDKGIHHRKL-KKSLIDMYS 288
Query: 891 SILEVLSYQDAAF-TYHHIQEIMV 913
+L+VLS DA++ T H+ ++V
Sbjct: 289 EVLDVLSDYDASYNTQDHLPRVVV 312
>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
Length = 978
Score = 37.0 bits (84), Expect = 0.18
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 833 KQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDD--MQHQVLERKYCVELLN 890
K+K+ + E + K Q + L KEL++L+ QKDD + H+ L +K +++ +
Sbjct: 230 KEKIDQLQEELLHTQLKYQRILE-RLEKENKELRKLVLQKDDKGIHHRKL-KKSLIDMYS 287
Query: 891 SILEVLSYQDAAF-TYHHIQEIMV 913
+L+VLS DA++ T H+ ++V
Sbjct: 288 EVLDVLSDYDASYNTQDHLPRVVV 311
>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
Length = 961
Score = 37.0 bits (84), Expect = 0.18
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 833 KQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDD--MQHQVLERKYCVELLN 890
K+K+ + E + K Q + L KEL++L+ QKDD + H+ L +K +++ +
Sbjct: 213 KEKIDQLQEELLHTQLKYQRILE-RLEKENKELRKLVLQKDDKGIHHRKL-KKSLIDMYS 270
Query: 891 SILEVLSYQDAAF-TYHHIQEIMV 913
+L+VLS DA++ T H+ ++V
Sbjct: 271 EVLDVLSDYDASYNTQDHLPRVVV 294
>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
Length = 942
Score = 37.0 bits (84), Expect = 0.18
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 833 KQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDD--MQHQVLERKYCVELLN 890
K+K+ + E + K Q + L KEL++L+ QKDD + H+ L +K +++ +
Sbjct: 194 KEKIDQLQEELLHTQLKYQRILE-RLEKENKELRKLVLQKDDKGIHHRKL-KKSLIDMYS 251
Query: 891 SILEVLSYQDAAF-TYHHIQEIMV 913
+L+VLS DA++ T H+ ++V
Sbjct: 252 EVLDVLSDYDASYNTQDHLPRVVV 275
>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
Length = 924
Score = 37.0 bits (84), Expect = 0.18
Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 833 KQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDD--MQHQVLERKYCVELLN 890
K+K+ + E + K Q + L KEL++L+ QKDD + H+ L +K +++ +
Sbjct: 176 KEKIDQLQEELLHTQLKYQRILE-RLEKENKELRKLVLQKDDKGIHHRKL-KKSLIDMYS 233
Query: 891 SILEVLSYQDAAF-TYHHIQEIMV 913
+L+VLS DA++ T H+ ++V
Sbjct: 234 EVLDVLSDYDASYNTQDHLPRVVV 257
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,066,479
Number of Sequences: 37866
Number of extensions: 2861183
Number of successful extensions: 8036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 84
Number of HSP's that attempted gapping in prelim test: 7842
Number of HSP's gapped (non-prelim): 221
length of query: 1830
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1713
effective length of database: 13,817,196
effective search space: 23668856748
effective search space used: 23668856748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.