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Search of human proteins with 30039698
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30039698 Ras association (RalGDS/AF-6) domain family member
3 [Homo sapiens]
(238 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30039698 Ras association (RalGDS/AF-6) domain family member 3... 482 e-136
gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isofor... 213 2e-55
gi|25777682 Ras association domain family 1 isoform C [Homo sapi... 184 8e-47
gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isofor... 181 4e-46
gi|25777684 Ras association domain family 1 isoform D [Homo sapi... 167 7e-42
gi|20149588 Ras association domain family 1 isoform A [Homo sapi... 167 7e-42
gi|25777680 Ras association domain family 1 isoform B [Homo sapi... 150 7e-37
gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isofor... 85 6e-17
gi|25777677 Ras association domain family 2 [Homo sapiens] 68 6e-12
gi|7661964 Ras association domain family 2 [Homo sapiens] 68 6e-12
gi|23510360 Ras association domain family 4 [Homo sapiens] 64 1e-10
gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isofor... 41 0.001
gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isofor... 41 0.001
gi|103471999 serine/threonine kinase 3 [Homo sapiens] 34 0.13
gi|219521893 coiled-coil transcriptional coactivator isoform 2 [... 33 0.17
gi|14149742 coiled-coil transcriptional coactivator isoform 1 [H... 33 0.17
gi|149363664 septin 8 isoform d [Homo sapiens] 33 0.28
gi|149363638 septin 8 isoform c [Homo sapiens] 33 0.28
gi|149363689 septin 8 isoform a [Homo sapiens] 33 0.28
gi|149363661 septin 8 isoform b [Homo sapiens] 33 0.28
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 31 0.82
gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens] 30 1.8
gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens] 30 1.8
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 30 1.8
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 30 1.8
gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens] 30 1.8
gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens] 30 1.8
gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens] 30 1.8
gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens] 30 1.8
gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens] 30 1.8
>gi|30039698 Ras association (RalGDS/AF-6) domain family member 3
[Homo sapiens]
Length = 238
Score = 482 bits (1240), Expect = e-136
Identities = 238/238 (100%), Positives = 238/238 (100%)
Query: 1 MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHK 60
MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHK
Sbjct: 1 MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHK 60
Query: 61 YNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCMNTLHISSTNT 120
YNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCMNTLHISSTNT
Sbjct: 61 YNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCMNTLHISSTNT 120
Query: 121 VGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSF 180
VGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSF
Sbjct: 121 VGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSF 180
Query: 181 VLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREVWKPD 238
VLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREVWKPD
Sbjct: 181 VLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREVWKPD 238
>gi|32996735 Ras association (RalGDS/AF-6) domain family 5 isoform C
[Homo sapiens]
Length = 265
Score = 213 bits (541), Expect = 2e-55
Identities = 124/255 (48%), Positives = 172/255 (67%), Gaps = 24/255 (9%)
Query: 1 MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHK 60
MSSGY SL+E+ ED FFTA+T+FFR A Q K S + + +ET + +EIK+K+
Sbjct: 7 MSSGYCSLDEELEDCFFTAKTTFFRNA-QSKHLS-KNVCKPVEETQRPPTLQEIKQKIDS 64
Query: 61 YNLAVTDKLKMTLNSNGIYTGFIKVQMELCKP--------PQTSPNSGK---LSPSSN-- 107
YN + L M L+ +G YTGFIKV ++L +P PQ+ ++ K L+ +++
Sbjct: 65 YNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNLAATTDKR 124
Query: 108 -------GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSD 160
+ LHISST TV EVI+ LLKKF+V ++P KFAL+KR H++ QV KLS
Sbjct: 125 TSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSI 184
Query: 161 REHPLYLRLVAGPRTDTLSFVLREHEIG--EWEAFSLPELQNFLRILDKEEDEQLQNLKR 218
+ PLYLRL+AGP T+ LSFVL+E+E G EW+AFS+PELQNFL IL+KEE +++Q +++
Sbjct: 185 ADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIQQVQK 244
Query: 219 RYTAYRQKLEEALRE 233
+Y +RQKLEEALRE
Sbjct: 245 KYDKFRQKLEEALRE 259
>gi|25777682 Ras association domain family 1 isoform C [Homo
sapiens]
Length = 270
Score = 184 bits (466), Expect = 8e-47
Identities = 116/256 (45%), Positives = 151/256 (58%), Gaps = 35/256 (13%)
Query: 2 SSGYSSLEEDAEDF--FFTARTSFFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVH 59
SSGY S E+ + +FTARTS RR PR QD E ET LS+ EI++K+
Sbjct: 18 SSGYCSQEDSDSELEQYFTARTSLARR-----PRR-DQDEPVEWETPD-LSQAEIEQKIK 70
Query: 60 KYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPS-------------- 105
+YN + L M+LN +G YTGFIKVQ++L +P S S K PS
Sbjct: 71 EYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRP--VSVPSSKKPPSLQDARRGPGRGTSV 128
Query: 106 --------SNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACK 157
+ LH+ S EVIEALL+KFLV + P KFAL++R R QVY K
Sbjct: 129 RRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRK 188
Query: 158 LSDREHPLYLRLVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRILDKEEDEQLQN 215
L D E PL LRL+AGP LSFVL+E++ GE W+AFS+PEL NFLRIL +EE+E L+
Sbjct: 189 LLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQ 248
Query: 216 LKRRYTAYRQKLEEAL 231
+ ++Y+ RQK++EAL
Sbjct: 249 ILQKYSYCRQKIQEAL 264
>gi|32996731 Ras association (RalGDS/AF-6) domain family 5 isoform A
[Homo sapiens]
Length = 418
Score = 181 bits (460), Expect = 4e-46
Identities = 102/213 (47%), Positives = 144/213 (67%), Gaps = 22/213 (10%)
Query: 43 KETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKP--------PQ 94
+ET + +EIK+K+ YN + L M L+ +G YTGFIKV ++L +P PQ
Sbjct: 200 EETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQ 259
Query: 95 TSPNSGK---LSPSSN---------GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFA 142
+ ++ K L+ +++ + LHISST TV EVI+ LLKKF+V ++P KFA
Sbjct: 260 SIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFA 319
Query: 143 LYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIG--EWEAFSLPELQN 200
L+KR H++ QV KLS + PLYLRL+AGP T+ LSFVL+E+E G EW+AFS+PELQN
Sbjct: 320 LFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDAFSIPELQN 379
Query: 201 FLRILDKEEDEQLQNLKRRYTAYRQKLEEALRE 233
FL IL+KEE +++Q ++++Y +RQKLEEALRE
Sbjct: 380 FLTILEKEEQDKIQQVQKKYDKFRQKLEEALRE 412
>gi|25777684 Ras association domain family 1 isoform D [Homo
sapiens]
Length = 344
Score = 167 bits (423), Expect = 7e-42
Identities = 95/207 (45%), Positives = 127/207 (61%), Gaps = 26/207 (12%)
Query: 49 LSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPS--- 105
LS+ EI++K+ +YN + L M+LN +G YTGFIKVQ++L +P S S K PS
Sbjct: 134 LSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRP--VSVPSSKKPPSLQD 191
Query: 106 -------------------SNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKR 146
+ LH+ S EVIEALL+KFLV + P KFAL++R
Sbjct: 192 ARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFER 251
Query: 147 CHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRI 204
R QVY KL D E PL LRL+AGP LSFVL+E++ GE W+AFS+PEL NFLRI
Sbjct: 252 AERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRI 311
Query: 205 LDKEEDEQLQNLKRRYTAYRQKLEEAL 231
L +EE+E L+ + ++Y+ RQK++EAL
Sbjct: 312 LQREEEEHLRQILQKYSYCRQKIQEAL 338
>gi|20149588 Ras association domain family 1 isoform A [Homo
sapiens]
Length = 340
Score = 167 bits (423), Expect = 7e-42
Identities = 95/207 (45%), Positives = 127/207 (61%), Gaps = 26/207 (12%)
Query: 49 LSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPS--- 105
LS+ EI++K+ +YN + L M+LN +G YTGFIKVQ++L +P S S K PS
Sbjct: 130 LSQAEIEQKIKEYNAQINSNLFMSLNKDGSYTGFIKVQLKLVRP--VSVPSSKKPPSLQD 187
Query: 106 -------------------SNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKR 146
+ LH+ S EVIEALL+KFLV + P KFAL++R
Sbjct: 188 ARRGPGRGTSVRRRTSFYLPKDAVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFER 247
Query: 147 CHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRI 204
R QVY KL D E PL LRL+AGP LSFVL+E++ GE W+AFS+PEL NFLRI
Sbjct: 248 AERHGQVYLRKLLDDEQPLRLRLLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRI 307
Query: 205 LDKEEDEQLQNLKRRYTAYRQKLEEAL 231
L +EE+E L+ + ++Y+ RQK++EAL
Sbjct: 308 LQREEEEHLRQILQKYSYCRQKIQEAL 334
>gi|25777680 Ras association domain family 1 isoform B [Homo
sapiens]
Length = 189
Score = 150 bits (380), Expect = 7e-37
Identities = 87/185 (47%), Positives = 113/185 (61%), Gaps = 26/185 (14%)
Query: 71 MTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPS----------------------SNG 108
M+LN +G YTGFIKVQ++L +P S S K PS
Sbjct: 1 MSLNKDGSYTGFIKVQLKLVRP--VSVPSSKKPPSLQDARRGPGRGTSVRRRTSFYLPKD 58
Query: 109 CMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLR 168
+ LH+ S EVIEALL+KFLV + P KFAL++R R QVY KL D E PL LR
Sbjct: 59 AVKHLHVLSRTRAREVIEALLRKFLVVDDPRKFALFERAERHGQVYLRKLLDDEQPLRLR 118
Query: 169 LVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQK 226
L+AGP LSFVL+E++ GE W+AFS+PEL NFLRIL +EE+E L+ + ++Y+ RQK
Sbjct: 119 LLAGPSDKALSFVLKENDSGEVNWDAFSMPELHNFLRILQREEEEHLRQILQKYSYCRQK 178
Query: 227 LEEAL 231
++EAL
Sbjct: 179 IQEAL 183
>gi|32996733 Ras association (RalGDS/AF-6) domain family 5 isoform B
[Homo sapiens]
Length = 336
Score = 84.7 bits (208), Expect = 6e-17
Identities = 52/131 (39%), Positives = 78/131 (59%), Gaps = 20/131 (15%)
Query: 43 KETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKP--------PQ 94
+ET + +EIK+K+ YN + L M L+ +G YTGFIKV ++L +P PQ
Sbjct: 200 EETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQ 259
Query: 95 TSPNSGK---LSPSSN---------GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFA 142
+ ++ K L+ +++ + LHISST TV EVI+ LLKKF+V ++P KFA
Sbjct: 260 SIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFA 319
Query: 143 LYKRCHREDQV 153
L+KR H++ QV
Sbjct: 320 LFKRIHKDGQV 330
>gi|25777677 Ras association domain family 2 [Homo sapiens]
Length = 326
Score = 68.2 bits (165), Expect = 6e-12
Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 11/135 (8%)
Query: 108 GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYL 167
G + + I+ST T +V++ LL KF + S +FALY H + K +D +PL
Sbjct: 188 GSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYV-VHTSGEKQKLKATD--YPLIA 244
Query: 168 RLVAGPRTDTLSFVLRE--------HEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRR 219
R++ GP L E +++ ++ F +P L++F++ L +EED +++ L R+
Sbjct: 245 RILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRK 304
Query: 220 YTAYRQKLEEALREV 234
YT R + + L E+
Sbjct: 305 YTVLRLMIRQRLEEI 319
>gi|7661964 Ras association domain family 2 [Homo sapiens]
Length = 326
Score = 68.2 bits (165), Expect = 6e-12
Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 11/135 (8%)
Query: 108 GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYL 167
G + + I+ST T +V++ LL KF + S +FALY H + K +D +PL
Sbjct: 188 GSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYV-VHTSGEKQKLKATD--YPLIA 244
Query: 168 RLVAGPRTDTLSFVLRE--------HEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRR 219
R++ GP L E +++ ++ F +P L++F++ L +EED +++ L R+
Sbjct: 245 RILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKKLMRK 304
Query: 220 YTAYRQKLEEALREV 234
YT R + + L E+
Sbjct: 305 YTVLRLMIRQRLEEI 319
>gi|23510360 Ras association domain family 4 [Homo sapiens]
Length = 321
Score = 63.9 bits (154), Expect = 1e-10
Identities = 40/135 (29%), Positives = 69/135 (51%), Gaps = 11/135 (8%)
Query: 108 GCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYL 167
G + + ++ST T +V+ LL KF V + P++FALY H + KL D E+PL
Sbjct: 186 GSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALY-IVHESGE--RTKLKDCEYPLIS 242
Query: 168 RLVAGPRTDTLSFVLRE--------HEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRR 219
R++ GP L E HE+ ++ F +P L +F+ L +EE+ ++ L +
Sbjct: 243 RILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMK 302
Query: 220 YTAYRQKLEEALREV 234
+ A R + + L ++
Sbjct: 303 FQALRLTMLQRLEQL 317
>gi|41393610 Ras association (RalGDS/AF-6) domain family 6 isoform b
[Homo sapiens]
Length = 369
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 10/115 (8%)
Query: 113 LHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAG 172
+ ++S EVI+ LL+KF + SP FAL+ +Q +L + PL RL+ G
Sbjct: 235 VRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ---RRLKKTDIPLLQRLLQG 291
Query: 173 PRTDTLSFVLRE-------HEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRY 220
P L + ++ ++ F L++ L+ L++EE ++Q + ++
Sbjct: 292 PSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRIVTKF 346
>gi|29789443 Ras association (RalGDS/AF-6) domain family 6 isoform a
[Homo sapiens]
Length = 337
Score = 40.8 bits (94), Expect = 0.001
Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 10/115 (8%)
Query: 113 LHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAG 172
+ ++S EVI+ LL+KF + SP FAL+ +Q +L + PL RL+ G
Sbjct: 203 VRVNSNMRTEEVIKQLLQKFKIENSPQDFALHIIFATGEQ---RRLKKTDIPLLQRLLQG 259
Query: 173 PRTDTLSFVLRE-------HEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRRY 220
P L + ++ ++ F L++ L+ L++EE ++Q + ++
Sbjct: 260 PSEKNARIFLMDKDAEEISSDVAQYINFHFSLLESILQRLNEEEKREIQRIVTKF 314
>gi|103471999 serine/threonine kinase 3 [Homo sapiens]
Length = 491
Score = 33.9 bits (76), Expect = 0.13
Identities = 16/38 (42%), Positives = 26/38 (68%)
Query: 194 SLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEAL 231
SL ELQ L+ LD + +++ L++RYTA RQ + +A+
Sbjct: 444 SLEELQMRLKALDPMMEREIEELRQRYTAKRQPILDAM 481
>gi|219521893 coiled-coil transcriptional coactivator isoform 2
[Homo sapiens]
Length = 606
Score = 33.5 bits (75), Expect = 0.17
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 5/48 (10%)
Query: 195 LPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREV----WKPD 238
L EL++ LR+L KE+ EQLQ K+ Y +KLE L +V W D
Sbjct: 387 LTELRSALRVLQKEK-EQLQEEKQELLEYMRKLEARLEKVADEKWNED 433
>gi|14149742 coiled-coil transcriptional coactivator isoform 1 [Homo
sapiens]
Length = 691
Score = 33.5 bits (75), Expect = 0.17
Identities = 21/48 (43%), Positives = 28/48 (58%), Gaps = 5/48 (10%)
Query: 195 LPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREV----WKPD 238
L EL++ LR+L KE+ EQLQ K+ Y +KLE L +V W D
Sbjct: 472 LTELRSALRVLQKEK-EQLQEEKQELLEYMRKLEARLEKVADEKWNED 518
>gi|149363664 septin 8 isoform d [Homo sapiens]
Length = 369
Score = 32.7 bits (73), Expect = 0.28
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 141 FALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLR-EHEIGEWEAFSLPELQ 199
+ LY+RC E+ + D + R + LS + R E E+ + + E +
Sbjct: 237 YELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETE 296
Query: 200 NFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREV 234
L+ ++E E+ ++LKR + ++K+EE RE+
Sbjct: 297 LELKEKERELHEKFEHLKRVHQEEKRKVEEKRREL 331
>gi|149363638 septin 8 isoform c [Homo sapiens]
Length = 442
Score = 32.7 bits (73), Expect = 0.28
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 141 FALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLR-EHEIGEWEAFSLPELQ 199
+ LY+RC E+ + D + R + LS + R E E+ + + E +
Sbjct: 297 YELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETE 356
Query: 200 NFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREV 234
L+ ++E E+ ++LKR + ++K+EE RE+
Sbjct: 357 LELKEKERELHEKFEHLKRVHQEEKRKVEEKRREL 391
>gi|149363689 septin 8 isoform a [Homo sapiens]
Length = 483
Score = 32.7 bits (73), Expect = 0.28
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 141 FALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLR-EHEIGEWEAFSLPELQ 199
+ LY+RC E+ + D + R + LS + R E E+ + + E +
Sbjct: 297 YELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETE 356
Query: 200 NFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREV 234
L+ ++E E+ ++LKR + ++K+EE RE+
Sbjct: 357 LELKEKERELHEKFEHLKRVHQEEKRKVEEKRREL 391
>gi|149363661 septin 8 isoform b [Homo sapiens]
Length = 429
Score = 32.7 bits (73), Expect = 0.28
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 141 FALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLR-EHEIGEWEAFSLPELQ 199
+ LY+RC E+ + D + R + LS + R E E+ + + E +
Sbjct: 297 YELYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFLSELQRKEEEMRQMFVNKVKETE 356
Query: 200 NFLRILDKEEDEQLQNLKRRYTAYRQKLEEALREV 234
L+ ++E E+ ++LKR + ++K+EE RE+
Sbjct: 357 LELKEKERELHEKFEHLKRVHQEEKRKVEEKRREL 391
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 31.2 bits (69), Expect = 0.82
Identities = 49/234 (20%), Positives = 90/234 (38%), Gaps = 34/234 (14%)
Query: 2 SSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEK-------EKETHSYLS---- 50
SS LE++ + S +R Q + + + +EK EK+ H S
Sbjct: 503 SSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDK 562
Query: 51 -KEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGC 109
KE+ ++K+HK+ A+ +K + T +VQ + + K N
Sbjct: 563 GKEDTQKKIHKFEEALKEKEEQ-------LTRVTEVQRLQAQQADAALEEFKRQVELNS- 614
Query: 110 MNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYK----RCHREDQVYACKLSDREHPL 165
++ + +V L + + E +K L++ R E Q+ KL +
Sbjct: 615 -EKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKT 673
Query: 166 YLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKRR 219
+L D+L +R+HE + L+ LR + E + Q+Q K+R
Sbjct: 674 HLLQQHNAEKDSL---VRDHE------REIENLEKQLRAANMEHENQIQEFKKR 718
>gi|225735629 disco-interacting protein 2A isoform g [Homo sapiens]
Length = 1567
Score = 30.0 bits (66), Expect = 1.8
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 70 KMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCM----NTLHISSTNTVGEV 124
K L+ NG+ G I+V E T + G++ P +N C+ T ++ T+ VGE+
Sbjct: 686 KAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEI 744
>gi|45827692 disco-interacting protein 2A isoform a [Homo sapiens]
Length = 1571
Score = 30.0 bits (66), Expect = 1.8
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 70 KMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCM----NTLHISSTNTVGEV 124
K L+ NG+ G I+V E T + G++ P +N C+ T ++ T+ VGE+
Sbjct: 690 KAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEI 748
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 30.0 bits (66), Expect = 1.8
Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 18/133 (13%)
Query: 105 SSNGCMNTLHISSTNTVGEVIEALLKKF---LVTESPAKFALYKRCHREDQVYACKLSDR 161
+ N + +SST T +VIE L +KF + S K++LY+ H + +L
Sbjct: 52 AGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYE-VHVSGE---RRLDID 107
Query: 162 EHPLYLRLVAGPRTDTLSFVLREHE--IGEWEAFSLPE-------LQNFLRILDKEEDEQ 212
E PL ++L FVL+ I + PE +QNF R L K+E ++
Sbjct: 108 EKPLVVQLNWNKDDREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKE 167
Query: 213 LQNLKRRYTAYRQ 225
+ KR A RQ
Sbjct: 168 KK--KREKEALRQ 178
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 30.0 bits (66), Expect = 1.8
Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 18/133 (13%)
Query: 105 SSNGCMNTLHISSTNTVGEVIEALLKKF---LVTESPAKFALYKRCHREDQVYACKLSDR 161
+ N + +SST T +VIE L +KF + S K++LY+ H + +L
Sbjct: 52 AGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYE-VHVSGE---RRLDID 107
Query: 162 EHPLYLRLVAGPRTDTLSFVLREHE--IGEWEAFSLPE-------LQNFLRILDKEEDEQ 212
E PL ++L FVL+ I + PE +QNF R L K+E ++
Sbjct: 108 EKPLVVQLNWNKDDREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKE 167
Query: 213 LQNLKRRYTAYRQ 225
+ KR A RQ
Sbjct: 168 KK--KREKEALRQ 178
>gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens]
Length = 798
Score = 30.0 bits (66), Expect = 1.8
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 70 KMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCM----NTLHISSTNTVGEV 124
K L+ NG+ G I+V E T + G++ P +N C+ T ++ T+ VGE+
Sbjct: 647 KAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEI 705
>gi|225735625 disco-interacting protein 2A isoform e [Homo sapiens]
Length = 1110
Score = 30.0 bits (66), Expect = 1.8
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 70 KMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCM----NTLHISSTNTVGEV 124
K L+ NG+ G I+V E T + G++ P +N C+ T ++ T+ VGE+
Sbjct: 626 KAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEI 684
>gi|45827698 disco-interacting protein 2A isoform d [Homo sapiens]
Length = 812
Score = 30.0 bits (66), Expect = 1.8
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 70 KMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCM----NTLHISSTNTVGEV 124
K L+ NG+ G I+V E T + G++ P +N C+ T ++ T+ VGE+
Sbjct: 690 KAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEI 748
>gi|45827696 disco-interacting protein 2A isoform c [Homo sapiens]
Length = 841
Score = 30.0 bits (66), Expect = 1.8
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 70 KMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCM----NTLHISSTNTVGEV 124
K L+ NG+ G I+V E T + G++ P +N C+ T ++ T+ VGE+
Sbjct: 690 KAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEI 748
>gi|45827694 disco-interacting protein 2A isoform b [Homo sapiens]
Length = 889
Score = 30.0 bits (66), Expect = 1.8
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 70 KMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKLSPSSNGCM----NTLHISSTNTVGEV 124
K L+ NG+ G I+V E T + G++ P +N C+ T ++ T+ VGE+
Sbjct: 690 KAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEI 748
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,868,745
Number of Sequences: 37866
Number of extensions: 460728
Number of successful extensions: 2358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 2307
Number of HSP's gapped (non-prelim): 66
length of query: 238
length of database: 18,247,518
effective HSP length: 99
effective length of query: 139
effective length of database: 14,498,784
effective search space: 2015330976
effective search space used: 2015330976
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.