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Search of human proteins with 30023828
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30023828 thioredoxin domain containing 6 [Homo sapiens]
(263 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30023828 thioredoxin domain containing 6 [Homo sapiens] 534 e-152
gi|148839372 thioredoxin domain containing 3 [Homo sapiens] 121 5e-28
gi|4505413 non-metastatic cells 5, protein expressed in (nucleos... 88 9e-18
gi|5031951 nucleoside diphosphate kinase type 6 [Homo sapiens] 82 6e-16
gi|37574614 nucleoside diphosphate kinase 7 isoform b [Homo sapi... 81 8e-16
gi|7019465 nucleoside diphosphate kinase 7 isoform a [Homo sapiens] 81 8e-16
gi|66392203 NME1-NME2 protein [Homo sapiens] 60 2e-09
gi|66392227 nucleoside diphosphate kinase B [Homo sapiens] 59 4e-09
gi|66392205 nucleoside diphosphate kinase B [Homo sapiens] 59 4e-09
gi|66392192 nucleoside diphosphate kinase B [Homo sapiens] 59 4e-09
gi|4505409 nucleoside diphosphate kinase B [Homo sapiens] 59 4e-09
gi|37693993 nucleoside diphosphate kinase 3 [Homo sapiens] 59 6e-09
gi|38045913 non-metastatic cells 1, protein (NM23A) expressed in... 58 7e-09
gi|4557797 non-metastatic cells 1, protein (NM23A) expressed in ... 58 7e-09
gi|4826862 nucleoside diphosphate kinase 4 [Homo sapiens] 54 1e-07
gi|50592994 thioredoxin [Homo sapiens] 39 0.004
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 35 0.067
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 35 0.067
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 35 0.067
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 34 0.15
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 34 0.15
gi|21361403 thioredoxin 2 precursor [Homo sapiens] 33 0.19
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 33 0.19
gi|95113651 glutaredoxin 3 [Homo sapiens] 31 0.96
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens] 31 0.96
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 30 2.8
gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform ... 29 3.7
gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein... 29 3.7
gi|122937271 WAS protein homolog associated with actin, golgi me... 29 4.8
gi|4506787 IQ motif containing GTPase activating protein 1 [Homo... 28 6.2
>gi|30023828 thioredoxin domain containing 6 [Homo sapiens]
Length = 263
Score = 534 bits (1376), Expect = e-152
Identities = 263/263 (100%), Positives = 263/263 (100%)
Query: 1 MLSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRLDVLEKYRGKCE 60
MLSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRLDVLEKYRGKCE
Sbjct: 1 MLSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRLDVLEKYRGKCE 60
Query: 61 PTFLFYAIKDEALSDEDECVSHGKNNGEDEDMVSSERTCTLAIIKPDAVAHGKTDEIIMK 120
PTFLFYAIKDEALSDEDECVSHGKNNGEDEDMVSSERTCTLAIIKPDAVAHGKTDEIIMK
Sbjct: 61 PTFLFYAIKDEALSDEDECVSHGKNNGEDEDMVSSERTCTLAIIKPDAVAHGKTDEIIMK 120
Query: 121 IQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTEGFEDV 180
IQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTEGFEDV
Sbjct: 121 IQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTEGFEDV 180
Query: 181 VTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAVHGSRDREDADRELALLFPSLKFS 240
VTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAVHGSRDREDADRELALLFPSLKFS
Sbjct: 181 VTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAVHGSRDREDADRELALLFPSLKFS 240
Query: 241 DKDTEAPQGESSTQPRLKITDLD 263
DKDTEAPQGESSTQPRLKITDLD
Sbjct: 241 DKDTEAPQGESSTQPRLKITDLD 263
>gi|148839372 thioredoxin domain containing 3 [Homo sapiens]
Length = 588
Score = 121 bits (304), Expect = 5e-28
Identities = 85/237 (35%), Positives = 122/237 (51%), Gaps = 37/237 (15%)
Query: 1 MLSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLD-LLHFALAEADRLDVLEKYRGKC 59
ML +KGLTV+DVYQ WCGPC+ + LF+K++ E+ D +LHFA+AEAD + L+ +R KC
Sbjct: 23 MLQNKGLTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEILHFAVAEADNIVTLQPFRDKC 82
Query: 60 EPTFLFYAI-----------------KDEALSDEDECVSHGKNNG---------EDEDMV 93
EP FLF K L DE+ ++ G+ + + V
Sbjct: 83 EPVFLFSVNGKIIEKIQGANAPLVNKKVINLIDEERKIAAGEMARPQYPEIPLVDSDSEV 142
Query: 94 SSERTC-------TLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQ 146
S E C ++AIIKPDAV K EI KI +AGF I + +TE +V FY
Sbjct: 143 SEESPCESVQELYSIAIIKPDAVISKKVLEIKRKITKAGFIIEAEHKTVLTEEQVVNFYS 202
Query: 147 HKAGEEAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRT-VMGPRDPNVARREQPE 202
A + FE+ V M SG S++L++ ++G + + T +PN +QPE
Sbjct: 203 RIADQCDFEEFVSFMTSGLSYILVV--SQGSKHNPPSEETEPQTDTEPNERSEDQPE 257
Score = 82.4 bits (202), Expect = 4e-16
Identities = 48/145 (33%), Positives = 81/145 (55%), Gaps = 6/145 (4%)
Query: 92 MVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGE 151
M S + TLA+++P+ + H + D+++ I++ F+IL + ++E E + + E
Sbjct: 310 MKSMKLEKTLALLRPN-LFHERKDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYENE 368
Query: 152 EAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTE 211
+ F KL+ +M SGPS L+L R G + W+ ++GPR A PESL AQ+ +
Sbjct: 369 DYFNKLIENMTSGPSLALVLLRDNGLQ----YWKQLLGPRTVEEAIEYFPESLCAQFAMD 424
Query: 212 -MPFNAVHGSRDREDADRELALLFP 235
+P N ++GS E A+RE+ FP
Sbjct: 425 SLPVNQLYGSDSLETAEREIQHFFP 449
Score = 80.5 bits (197), Expect = 1e-15
Identities = 43/135 (31%), Positives = 77/135 (57%), Gaps = 5/135 (3%)
Query: 100 TLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVH 159
TL +IKP A + + ++I+ ++EAGF++ ++ +T ++ Y G++ ++ L+
Sbjct: 453 TLGLIKPHATSEQR-EQILKIVKEAGFDLTQVKKMFLTPEQIEKIYPKVTGKDFYKDLLE 511
Query: 160 HMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAVHG 219
+ GPS ++ILT+ + V WR +MGP DP A+ P+S+RAQ+G N VHG
Sbjct: 512 MLSVGPSMVMILTKW----NAVAEWRRLMGPTDPEEAKLLSPDSIRAQFGISKLKNIVHG 567
Query: 220 SRDREDADRELALLF 234
+ + +A + LF
Sbjct: 568 ASNAYEAKEVVNRLF 582
>gi|4505413 non-metastatic cells 5, protein expressed in
(nucleoside-diphosphate kinase) [Homo sapiens]
Length = 212
Score = 87.8 bits (216), Expect = 9e-18
Identities = 53/138 (38%), Positives = 77/138 (55%), Gaps = 6/138 (4%)
Query: 100 TLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVH 159
TLAIIKPD V K +EI I +GF I+ + ++ + FY K G+ F L
Sbjct: 15 TLAIIKPDIV--DKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTA 72
Query: 160 HMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAVHG 219
+M SGP +IL R + ++ W ++GP + VA+ P+SLRA YGT+ NA+HG
Sbjct: 73 YMSSGPLVAMILARHKA----ISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHG 128
Query: 220 SRDREDADRELALLFPSL 237
S D A+RE+ +FP +
Sbjct: 129 SNDFAAAEREIRFMFPEV 146
>gi|5031951 nucleoside diphosphate kinase type 6 [Homo sapiens]
Length = 194
Score = 81.6 bits (200), Expect = 6e-16
Identities = 55/153 (35%), Positives = 76/153 (49%), Gaps = 10/153 (6%)
Query: 100 TLAIIKPDAVAHGKTDEII-MKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLV 158
TLA+IKPDAVAH E + +I F I+ E + + + FY+ G +++LV
Sbjct: 22 TLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFFYQRLV 81
Query: 159 HHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAVH 218
M SGP IL +D + WRT+MGP AR P+S+R +G N H
Sbjct: 82 EFMASGPIRAYILAH----KDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTH 137
Query: 219 GSRDREDADRELALLFPSLKFSDK---DTEAPQ 248
GS A RE+A FP FS++ + E PQ
Sbjct: 138 GSDSVVSASREIAAFFPD--FSEQRWYEEEEPQ 168
>gi|37574614 nucleoside diphosphate kinase 7 isoform b [Homo
sapiens]
Length = 340
Score = 81.3 bits (199), Expect = 8e-16
Identities = 49/144 (34%), Positives = 76/144 (52%), Gaps = 6/144 (4%)
Query: 93 VSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEE 152
+ S + TLA+IKPDA++ K EII I +AGF I + ++ E F+
Sbjct: 51 LGSRKEKTLALIKPDAIS--KAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRP 108
Query: 153 AFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEM 212
F +L+ + +GP + + R +D + W+ ++GP + VAR + ES+RA +GT+
Sbjct: 109 FFNELIQFITTGPIIAMEILR----DDAICEWKRLLGPANSGVARTDASESIRALFGTDG 164
Query: 213 PFNAVHGSRDREDADRELALLFPS 236
NA HG A RE+ L FPS
Sbjct: 165 IRNAAHGPDSFASAAREMELFFPS 188
Score = 73.9 bits (180), Expect = 1e-13
Identities = 48/140 (34%), Positives = 70/140 (50%), Gaps = 5/140 (3%)
Query: 99 CTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQ-HKAGEEAFEKL 157
CT I+KP AV+ G +I+M I++AGFEI + M V FY+ +K + +
Sbjct: 203 CTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDM 262
Query: 158 VHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAV 217
V M SGP + + + + T+R GP DP +AR +P +LRA +G NAV
Sbjct: 263 VTEMYSGPCVAMEIQQ----NNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAV 318
Query: 218 HGSRDREDADRELALLFPSL 237
H + ED E+ F L
Sbjct: 319 HCTDLPEDGLLEVQYFFKIL 338
>gi|7019465 nucleoside diphosphate kinase 7 isoform a [Homo sapiens]
Length = 376
Score = 81.3 bits (199), Expect = 8e-16
Identities = 49/144 (34%), Positives = 76/144 (52%), Gaps = 6/144 (4%)
Query: 93 VSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEE 152
+ S + TLA+IKPDA++ K EII I +AGF I + ++ E F+
Sbjct: 87 LGSRKEKTLALIKPDAIS--KAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRP 144
Query: 153 AFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEM 212
F +L+ + +GP + + R +D + W+ ++GP + VAR + ES+RA +GT+
Sbjct: 145 FFNELIQFITTGPIIAMEILR----DDAICEWKRLLGPANSGVARTDASESIRALFGTDG 200
Query: 213 PFNAVHGSRDREDADRELALLFPS 236
NA HG A RE+ L FPS
Sbjct: 201 IRNAAHGPDSFASAAREMELFFPS 224
Score = 73.9 bits (180), Expect = 1e-13
Identities = 48/140 (34%), Positives = 70/140 (50%), Gaps = 5/140 (3%)
Query: 99 CTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQ-HKAGEEAFEKL 157
CT I+KP AV+ G +I+M I++AGFEI + M V FY+ +K + +
Sbjct: 239 CTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDM 298
Query: 158 VHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAV 217
V M SGP + + + + T+R GP DP +AR +P +LRA +G NAV
Sbjct: 299 VTEMYSGPCVAMEIQQ----NNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAV 354
Query: 218 HGSRDREDADRELALLFPSL 237
H + ED E+ F L
Sbjct: 355 HCTDLPEDGLLEVQYFFKIL 374
>gi|66392203 NME1-NME2 protein [Homo sapiens]
Length = 267
Score = 60.1 bits (144), Expect = 2e-09
Identities = 45/158 (28%), Positives = 76/158 (48%), Gaps = 15/158 (9%)
Query: 77 DECVSHGKNNGEDEDMVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTM 136
D C+ G+ M + ERT IKPD V G EII + ++ GF ++ +
Sbjct: 107 DFCIQVGRT------MANLERT--FIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRA 158
Query: 137 TEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVA 196
+E ++ Y F LV +M SGP ++ EG +VV T R ++G +P
Sbjct: 159 SEEHLKQHYIDLKDRPFFPGLVKYMNSGP---VVAMVWEGL-NVVKTGRVMLGETNP--- 211
Query: 197 RREQPESLRAQYGTEMPFNAVHGSRDREDADRELALLF 234
+P ++R + ++ N +HGS + A++E++L F
Sbjct: 212 ADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWF 249
Score = 41.6 bits (96), Expect = 7e-04
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Query: 92 MVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGE 151
M + ERT IKPD V G EII + ++ GF ++ + +E ++ Y
Sbjct: 1 MANCERT--FIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDR 58
Query: 152 EAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDP 193
F LV +M SGP ++ EG +VV T R ++G +P
Sbjct: 59 PFFAGLVKYMHSGP---VVAMVWEGL-NVVKTGRVMLGETNP 96
>gi|66392227 nucleoside diphosphate kinase B [Homo sapiens]
Length = 152
Score = 58.9 bits (141), Expect = 4e-09
Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 9/143 (6%)
Query: 92 MVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGE 151
M + ERT IKPD V G EII + ++ GF ++ + +E ++ Y
Sbjct: 1 MANLERT--FIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDR 58
Query: 152 EAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTE 211
F LV +M SGP ++ EG +VV T R ++G +P +P ++R + +
Sbjct: 59 PFFPGLVKYMNSGP---VVAMVWEGL-NVVKTGRVMLGETNP---ADSKPGTIRGDFCIQ 111
Query: 212 MPFNAVHGSRDREDADRELALLF 234
+ N +HGS + A++E++L F
Sbjct: 112 VGRNIIHGSDSVKSAEKEISLWF 134
>gi|66392205 nucleoside diphosphate kinase B [Homo sapiens]
Length = 152
Score = 58.9 bits (141), Expect = 4e-09
Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 9/143 (6%)
Query: 92 MVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGE 151
M + ERT IKPD V G EII + ++ GF ++ + +E ++ Y
Sbjct: 1 MANLERT--FIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDR 58
Query: 152 EAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTE 211
F LV +M SGP ++ EG +VV T R ++G +P +P ++R + +
Sbjct: 59 PFFPGLVKYMNSGP---VVAMVWEGL-NVVKTGRVMLGETNP---ADSKPGTIRGDFCIQ 111
Query: 212 MPFNAVHGSRDREDADRELALLF 234
+ N +HGS + A++E++L F
Sbjct: 112 VGRNIIHGSDSVKSAEKEISLWF 134
>gi|66392192 nucleoside diphosphate kinase B [Homo sapiens]
Length = 152
Score = 58.9 bits (141), Expect = 4e-09
Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 9/143 (6%)
Query: 92 MVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGE 151
M + ERT IKPD V G EII + ++ GF ++ + +E ++ Y
Sbjct: 1 MANLERT--FIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDR 58
Query: 152 EAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTE 211
F LV +M SGP ++ EG +VV T R ++G +P +P ++R + +
Sbjct: 59 PFFPGLVKYMNSGP---VVAMVWEGL-NVVKTGRVMLGETNP---ADSKPGTIRGDFCIQ 111
Query: 212 MPFNAVHGSRDREDADRELALLF 234
+ N +HGS + A++E++L F
Sbjct: 112 VGRNIIHGSDSVKSAEKEISLWF 134
>gi|4505409 nucleoside diphosphate kinase B [Homo sapiens]
Length = 152
Score = 58.9 bits (141), Expect = 4e-09
Identities = 42/143 (29%), Positives = 71/143 (49%), Gaps = 9/143 (6%)
Query: 92 MVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGE 151
M + ERT IKPD V G EII + ++ GF ++ + +E ++ Y
Sbjct: 1 MANLERT--FIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDR 58
Query: 152 EAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTE 211
F LV +M SGP ++ EG +VV T R ++G +P +P ++R + +
Sbjct: 59 PFFPGLVKYMNSGP---VVAMVWEGL-NVVKTGRVMLGETNP---ADSKPGTIRGDFCIQ 111
Query: 212 MPFNAVHGSRDREDADRELALLF 234
+ N +HGS + A++E++L F
Sbjct: 112 VGRNIIHGSDSVKSAEKEISLWF 134
>gi|37693993 nucleoside diphosphate kinase 3 [Homo sapiens]
Length = 169
Score = 58.5 bits (140), Expect = 6e-09
Identities = 41/135 (30%), Positives = 66/135 (48%), Gaps = 7/135 (5%)
Query: 100 TLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVH 159
T +KPD V EI+ + + GF+++ + +E +R Y + +LV
Sbjct: 24 TFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYAELRERPFYGRLVK 83
Query: 160 HMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAVHG 219
+M SGP ++ +G DVV T R ++G +P A P ++R + E+ N +HG
Sbjct: 84 YMASGP---VVAMVWQGL-DVVRTSRALIGATNPADA---PPGTIRGDFCIEVGKNLIHG 136
Query: 220 SRDREDADRELALLF 234
S E A RE+AL F
Sbjct: 137 SDSVESARREIALWF 151
>gi|38045913 non-metastatic cells 1, protein (NM23A) expressed in
isoform a [Homo sapiens]
Length = 177
Score = 58.2 bits (139), Expect = 7e-09
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 9/143 (6%)
Query: 92 MVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGE 151
M + ERT IKPD V G EII + ++ GF ++ + +E ++ Y
Sbjct: 26 MANCERT--FIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDR 83
Query: 152 EAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTE 211
F LV +M SGP ++ EG +VV T R ++G +P +P ++R + +
Sbjct: 84 PFFAGLVKYMHSGP---VVAMVWEGL-NVVKTGRVMLGETNP---ADSKPGTIRGDFCIQ 136
Query: 212 MPFNAVHGSRDREDADRELALLF 234
+ N +HGS E A++E+ L F
Sbjct: 137 VGRNIIHGSDSVESAEKEIGLWF 159
>gi|4557797 non-metastatic cells 1, protein (NM23A) expressed in
isoform b [Homo sapiens]
Length = 152
Score = 58.2 bits (139), Expect = 7e-09
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 9/143 (6%)
Query: 92 MVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGE 151
M + ERT IKPD V G EII + ++ GF ++ + +E ++ Y
Sbjct: 1 MANCERT--FIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDR 58
Query: 152 EAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTE 211
F LV +M SGP ++ EG +VV T R ++G +P +P ++R + +
Sbjct: 59 PFFAGLVKYMHSGP---VVAMVWEGL-NVVKTGRVMLGETNP---ADSKPGTIRGDFCIQ 111
Query: 212 MPFNAVHGSRDREDADRELALLF 234
+ N +HGS E A++E+ L F
Sbjct: 112 VGRNIIHGSDSVESAEKEIGLWF 134
>gi|4826862 nucleoside diphosphate kinase 4 [Homo sapiens]
Length = 187
Score = 53.9 bits (128), Expect = 1e-07
Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 7/140 (5%)
Query: 97 RTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEK 156
R TL +KPD V ++I + + GF ++ + E+ + YQ + +
Sbjct: 37 RERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPA 96
Query: 157 LVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNA 216
L+ +M SGP ++ EG+ +VV R ++G D + P ++R + + N
Sbjct: 97 LIRYMSSGP---VVAMVWEGY-NVVRASRAMIGHTD---SAEAAPGTIRGDFSVHISRNV 149
Query: 217 VHGSRDREDADRELALLFPS 236
+H S E A RE+ L F S
Sbjct: 150 IHASDSVEGAQREIQLWFQS 169
>gi|50592994 thioredoxin [Homo sapiens]
Length = 105
Score = 39.3 bits (90), Expect = 0.004
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 7 LTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRLDVLEKYRGKCEPTFLFY 66
L VVD WCGPCK + F + E +++ + D DV + KC PTF F+
Sbjct: 22 LVVVDFSATWCGPCKMIKPFFHSLS-EKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFF 80
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 35.0 bits (79), Expect = 0.067
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 7 LTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRL-DVLEKYRGKCEPTFLF 65
L VD WCGPC+ + F + ++ + + F +AD +V+ + C PTF F
Sbjct: 403 LVAVDFSATWCGPCRTIRPFFHALSVK--HEDVVFLEVDADNCEEVVRECAIMCVPTFQF 460
Query: 66 YAIKDEALSDE 76
Y K E DE
Sbjct: 461 Y--KKEEKVDE 469
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 35.0 bits (79), Expect = 0.067
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 7 LTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRL-DVLEKYRGKCEPTFLF 65
L VD WCGPC+ + F + ++ + + F +AD +V+ + C PTF F
Sbjct: 470 LVAVDFSATWCGPCRTIRPFFHALSVK--HEDVVFLEVDADNCEEVVRECAIMCVPTFQF 527
Query: 66 YAIKDEALSDE 76
Y K E DE
Sbjct: 528 Y--KKEEKVDE 536
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 35.0 bits (79), Expect = 0.067
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 7 LTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRL-DVLEKYRGKCEPTFLF 65
L VD WCGPC+ + F + ++ + + F +AD +V+ + C PTF F
Sbjct: 403 LVAVDFSATWCGPCRTIRPFFHALSVK--HEDVVFLEVDADNCEEVVRECAIMCVPTFQF 460
Query: 66 YAIKDEALSDE 76
Y K E DE
Sbjct: 461 Y--KKEEKVDE 469
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 33.9 bits (76), Expect = 0.15
Identities = 17/66 (25%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
Query: 4 SKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEAD---RLDVLEKYRGKCE 60
++G+T + Y WCG CK + ++++ + L +AE D ++ KY +
Sbjct: 337 AEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGY 396
Query: 61 PTFLFY 66
PT L +
Sbjct: 397 PTLLLF 402
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 33.9 bits (76), Expect = 0.15
Identities = 17/66 (25%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
Query: 4 SKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEAD---RLDVLEKYRGKCE 60
++G+T + Y WCG CK + ++++ + L +AE D ++ KY +
Sbjct: 229 AEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGY 288
Query: 61 PTFLFY 66
PT L +
Sbjct: 289 PTLLLF 294
>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
Length = 166
Score = 33.5 bits (75), Expect = 0.19
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 10/81 (12%)
Query: 1 MLSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRLDVLEKYRGKCE 60
+++S+ VVD + WCGPCK + +KM + ++ + D D+ +Y
Sbjct: 74 VVNSETPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAV 133
Query: 61 PTFL----------FYAIKDE 71
PT L F IKDE
Sbjct: 134 PTVLAMKNGDVVDKFVGIKDE 154
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 33.5 bits (75), Expect = 0.19
Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 11/114 (9%)
Query: 2 LSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEAD---RLDVLEKYRGK 58
L++ +V+ Y WCG CK + + K ++ + LA+ D D+ ++Y +
Sbjct: 38 LAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVR 97
Query: 59 CEPTFLFYAIKDEALSDEDECVSHGKNNGEDEDMVS--SERTCTLAIIKPDAVA 110
PT F+ D A E + G+ E +D+V+ +RT A PD A
Sbjct: 98 GYPTIKFFRNGDTASPKE---YTAGR---EADDIVNWLKKRTGPAATTLPDGAA 145
>gi|95113651 glutaredoxin 3 [Homo sapiens]
Length = 335
Score = 31.2 bits (69), Expect = 0.96
Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
Query: 2 LSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRL-DVLEKYRGKCE 60
L +K L VV + W C + + ++ E L + F EA+ + +V EKY
Sbjct: 28 LKAKSLLVVHFWAPWAPQCAQMNEVMAELAKE--LPQVSFVKLEAEGVPEVSEKYEISSV 85
Query: 61 PTFLFY 66
PTFLF+
Sbjct: 86 PTFLFF 91
>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
Length = 1012
Score = 31.2 bits (69), Expect = 0.96
Identities = 48/214 (22%), Positives = 76/214 (35%), Gaps = 34/214 (15%)
Query: 16 WCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRLDVLEKYRGKCEPTFLFYAIKDEALSD 75
W C ++S + +I + E +RL E + EP +DE S
Sbjct: 802 WINTCSCLLSNIKGRKITL------LTYEEIERLLEEEAVKEFIEPEIDESFKEDEEESK 855
Query: 76 EDECVSH-GKNNGEDEDMVSSERTCTLAIIKPDAVAHGK----TD------------EII 118
ED + K E++ S+E+ + I D H K TD +
Sbjct: 856 EDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESAKQGTLA 915
Query: 119 MKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTEGFE 178
K EA ++ + + + E E R + E+A+EKL H L + + E
Sbjct: 916 QKYLEA-MAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHH----------TLIKNKDLE 964
Query: 179 DVVTTWRTVMGPRDPNVARREQPESLRAQYGTEM 212
++V T R N RE E Q E+
Sbjct: 965 ELVMTSRKESKEEKENQDEREVKEEEEQQEEEEV 998
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 29.6 bits (65), Expect = 2.8
Identities = 11/28 (39%), Positives = 15/28 (53%)
Query: 1 MLSSKGLTVVDVYQGWCGPCKPVVSLFQ 28
+L K V+D Y WCGPC+ F+
Sbjct: 684 VLQGKNHWVIDFYAPWCGPCQNFAPEFE 711
>gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform 2
[Homo sapiens]
Length = 2044
Score = 29.3 bits (64), Expect = 3.7
Identities = 16/74 (21%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 119 MKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTEGFE 178
M +Q+ + + + T+A +L + ++ +L+HH+C GP L + G E
Sbjct: 1114 MMVQDLHSALDRSHPQHYTQAMFKLTAMLISSKDCDPQLLHHLCWGP---LRMFNEHGME 1170
Query: 179 DVVTTWRTVMGPRD 192
+ W ++ +D
Sbjct: 1171 TALACWEWLLAGKD 1184
>gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein
[Homo sapiens]
Length = 614
Score = 29.3 bits (64), Expect = 3.7
Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 7/82 (8%)
Query: 71 EALSDEDECVSHGKNNGEDEDMVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILT 130
E + + + + D+D S R C L K K + + K Q+ FE
Sbjct: 395 EMIKTQQQLLQQQLATAYDDDTTSLLRDCYLLEEKERL----KEEWSLFKEQKKNFE--- 447
Query: 131 NEERTMTEAEVRLFYQHKAGEE 152
E R+ TEA +RL + KA EE
Sbjct: 448 RERRSFTEAAIRLGLERKAFEE 469
>gi|122937271 WAS protein homolog associated with actin, golgi
membranes and microtubules [Homo sapiens]
Length = 809
Score = 28.9 bits (63), Expect = 4.8
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 116 EIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTE 175
EI +++ E FEIL NEE +T L + E+ E + + C P L ++
Sbjct: 391 EIQLELYEVKFEILKNEEILLTTQLDSL--KRLIKEKQDEVVYYDPCENPEELKVIDCVV 448
Query: 176 GFED 179
G +D
Sbjct: 449 GLQD 452
>gi|4506787 IQ motif containing GTPase activating protein 1 [Homo
sapiens]
Length = 1657
Score = 28.5 bits (62), Expect = 6.2
Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 10/65 (15%)
Query: 107 DAVAHGK----------TDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEK 156
D V+H K +D +++ Q+ G + L+ E+R EA LFY + K
Sbjct: 929 DVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAK 988
Query: 157 LVHHM 161
L+ M
Sbjct: 989 LIFQM 993
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,979,334
Number of Sequences: 37866
Number of extensions: 432563
Number of successful extensions: 1244
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1197
Number of HSP's gapped (non-prelim): 44
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.