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Search of human proteins with 122937345
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937345 myosin VB [Homo sapiens]
(1848 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937345 myosin VB [Homo sapiens] 3663 0.0
gi|215982791 myosin VA isoform 1 [Homo sapiens] 2295 0.0
gi|215982794 myosin VA isoform 2 [Homo sapiens] 2269 0.0
gi|153945715 myosin VC [Homo sapiens] 1646 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 596 e-170
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 596 e-170
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 594 e-169
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 594 e-169
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 589 e-168
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 587 e-167
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 583 e-166
gi|156104908 myosin heavy chain 6 [Homo sapiens] 583 e-166
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 582 e-165
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 580 e-165
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 579 e-164
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 575 e-163
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 570 e-162
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 569 e-161
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 566 e-161
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 566 e-161
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 566 e-161
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 564 e-160
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 564 e-160
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 558 e-158
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 558 e-158
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 557 e-158
gi|154354979 myosin X [Homo sapiens] 555 e-157
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 554 e-157
gi|122937512 myosin VIIB [Homo sapiens] 540 e-153
gi|194328685 myosin IB isoform 1 [Homo sapiens] 513 e-145
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 3663 bits (9499), Expect = 0.0
Identities = 1848/1848 (100%), Positives = 1848/1848 (100%)
Query: 1 MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLP 60
MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLP
Sbjct: 1 MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLP 60
Query: 61 FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYG 120
FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYG
Sbjct: 61 FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYG 120
Query: 121 QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF 180
QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF
Sbjct: 121 QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF 180
Query: 181 ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240
ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR
Sbjct: 181 ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240
Query: 241 TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD 300
TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD
Sbjct: 241 TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD 300
Query: 301 DAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSN 360
DAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSN
Sbjct: 301 DAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSN 360
Query: 361 FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI 420
FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI
Sbjct: 361 FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI 420
Query: 421 NKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480
NKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK
Sbjct: 421 NKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480
Query: 481 EQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK 540
EQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK
Sbjct: 481 EQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK 540
Query: 541 PRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVP 600
PRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVP
Sbjct: 541 PRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVP 600
Query: 601 ATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP 660
ATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP
Sbjct: 601 ATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP 660
Query: 661 NDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTD 720
NDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTD
Sbjct: 661 NDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTD 720
Query: 721 KKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQ 780
KKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQ
Sbjct: 721 KKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQ 780
Query: 781 KVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAV 840
KVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAV
Sbjct: 781 KVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAV 840
Query: 841 VIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKAR 900
VIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKAR
Sbjct: 841 VIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKAR 900
Query: 901 RELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVE 960
RELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVE
Sbjct: 901 RELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVE 960
Query: 961 RLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADL 1020
RLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADL
Sbjct: 961 RLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADL 1020
Query: 1021 EQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQR 1080
EQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQR
Sbjct: 1021 EQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQR 1080
Query: 1081 YDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAA 1140
YDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAA
Sbjct: 1081 YDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAA 1140
Query: 1141 MDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSL 1200
MDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSL
Sbjct: 1141 MDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSL 1200
Query: 1201 KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE 1260
KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE
Sbjct: 1201 KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE 1260
Query: 1261 VLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDW 1320
VLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDW
Sbjct: 1261 VLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDW 1320
Query: 1321 GYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFC 1380
GYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFC
Sbjct: 1321 GYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFC 1380
Query: 1381 QTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAA 1440
QTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAA
Sbjct: 1381 QTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAA 1440
Query: 1441 QALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSGTVPCL 1500
QALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSGTVPCL
Sbjct: 1441 QALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSGTVPCL 1500
Query: 1501 PAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCL 1560
PAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCL
Sbjct: 1501 PAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCL 1560
Query: 1561 KQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGVLQPMIVSA 1620
KQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGVLQPMIVSA
Sbjct: 1561 KQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGVLQPMIVSA 1620
Query: 1621 MLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQ 1680
MLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQ
Sbjct: 1621 MLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQ 1680
Query: 1681 VFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPL 1740
VFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPL
Sbjct: 1681 VFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPL 1740
Query: 1741 IQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQ 1800
IQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQ
Sbjct: 1741 IQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQ 1800
Query: 1801 LQERNDPQQLLLDAKHMFPVLFPFNPSSLTMDSIHIPACLNLEFLNEV 1848
LQERNDPQQLLLDAKHMFPVLFPFNPSSLTMDSIHIPACLNLEFLNEV
Sbjct: 1801 LQERNDPQQLLLDAKHMFPVLFPFNPSSLTMDSIHIPACLNLEFLNEV 1848
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 2295 bits (5946), Expect = 0.0
Identities = 1170/1868 (62%), Positives = 1456/1868 (77%), Gaps = 33/1868 (1%)
Query: 1 MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLP 60
M+ ELY++ RVWIPDP+EVW+SAEL KDYK GDK L L LE+ LEY +D + +LP
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60
Query: 61 FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYG 120
LRNPDILVGENDLTALSYLHEPAVLHNL+VRF++S IYTYCGIVLVAINPYEQLPIYG
Sbjct: 61 HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120
Query: 121 QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF 180
+D+I YSGQNMGDMDPHIFAVAEEAYKQMARDE+NQSIIVSGESGAGKTVSAKYAMRYF
Sbjct: 121 EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180
Query: 181 ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240
ATV GSASE N+EEKVLAS+PIME+IGNAKTTRNDNSSRFGKYI+IGFDKRY IIGANMR
Sbjct: 181 ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
Query: 241 TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD 300
TYLLEKSRVVFQA++ERNYHIFYQLCA+A LPEFK L L +A++F YT QGG IEGVD
Sbjct: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
Query: 301 DAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSN 360
DA++ TRQA TLLG+ ESHQM IF+I+A ILHLG+V RD DSC+I P+ L
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCI 359
Query: 361 FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI 420
FC L+GV++ +M HWLCHRKL T +ETY+K +S Q NAR+ALAKHIYA+LF WIV+++
Sbjct: 360 FCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNV 419
Query: 421 NKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480
N+ALH+++KQHSFIGVLDIYGFETFE+NSFEQFCINYANEKLQQQFN HVFKLEQEEYMK
Sbjct: 420 NQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 479
Query: 481 EQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQ 539
EQIPWTLIDFYDNQPCI+LIE+KLGILDLLDEECK+PKGTD WAQKLY+ H + F+
Sbjct: 480 EQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
Query: 540 KPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDK--- 596
KPR+SN AFII HFADKVEY +GFLEKN+DTV+EEQI +LK+SKF ++ +LF DD+
Sbjct: 540 KPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAI 599
Query: 597 DPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVR 656
P AT+ G+ ++ + + KEHKKTVGHQFR SLHLLMETLNATTPHYVR
Sbjct: 600 SPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVR 659
Query: 657 CIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKREL 716
CIKPND K PF FD KRAVQQLRACGVLETIRISAAG+PSRW Y +FF+RYRVL+K++++
Sbjct: 660 CIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDV 719
Query: 717 ANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVR 776
+D+K C++VLE LI D DK+QFG+TKIFFRAGQVAYLEKLRADK R A I IQKT+R
Sbjct: 720 L-SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIR 778
Query: 777 GWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVR 836
GWL + KY R++ A +T+QRY RG+ AR A+ LRR +AA ++QK++RM R+ Y+ R
Sbjct: 779 GWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRR 838
Query: 837 RAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRM 896
A +V+Q++ R R YR++L EHKA IQK VRGW+AR H++R A I +QC FR
Sbjct: 839 AATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRR 898
Query: 897 LKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYT 956
+ A+RELK L+IEARS E K+L++GMENK++QLQRK+DEQNK++K L E+L+ Y
Sbjct: 899 MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
Query: 957 MEVERLKKELVHYQQSPGE-----DTSLRLQEEVESLRTELQRAHSERKILEDAHSREKD 1011
E E+L+ +L Q S E L LQEE+ LR +L++ SE+K +E+ R K
Sbjct: 959 SETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQ 1018
Query: 1012 ELRKRVADLEQENALLKDEKEQLNNQILCQSKD--EFAQNSVKENLMKKELE--EERSRY 1067
E + V++L++EN LLK EKE LN++I+ Q+K+ E + + E + EL+ +ER RY
Sbjct: 1019 ETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078
Query: 1068 QNLVKEYSQLEQRYDNLRDEMTIIKQT--PGHRRNPSNQSSLESDSNYPSISTSEIGDTE 1125
QNL+ E+S+LE+RYD+L++EMT++ PGH+R S SS ES+ I +SEI + E
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE----YIFSSEIAEME 1134
Query: 1126 DALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQ--DSKKVQAEPP 1183
D + EE +K +DM++FLKLQKRV ELEQE++ +Q +L+++E+Q SK + E P
Sbjct: 1135 DIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERP 1194
Query: 1184 QTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLL 1243
Q A+L Y SLKRQELESENKKLKN+LNELRKA+++++ ++ G+P +Y +L
Sbjct: 1195 QI-----RGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP-AYRVL 1248
Query: 1244 LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA 1303
+ QL EEL+VRKEEVLILR+Q+VS + + ++ + +K D+ +
Sbjct: 1249 MEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEI 1308
Query: 1304 IEAYHGVCQTN-SKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLK 1362
+AY G+ +TN S D+ LNEDGEL L Y+GLKQ RLLE+QLQ+Q HE E E L+
Sbjct: 1309 AQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALR 1368
Query: 1363 AQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERK 1422
++++LKEE ++QQQ Q L L PEA++E +Q EI+RLTNENLDL E +EK +K RK
Sbjct: 1369 GEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRK 1428
Query: 1423 LKKQLKIYMKKAQDLEAAQALAQSERK-RHELNRQVTVQRKEKDFQGMLEYHKEDEALLI 1481
LKKQLK++ KK +LE Q S + E R V + RKEKDFQGMLEY KEDE L+
Sbjct: 1429 LKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLV 1488
Query: 1482 RNLVTDLKPQMLS-GTVPCLPAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHN 1540
+NL+ +LKP+ ++ +P LPAYIL+MC+RHADY NDD KV SLLTSTIN IKKVLKK
Sbjct: 1489 KNLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRG 1548
Query: 1541 DDFEMTSFWLSNTCRLLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQ 1600
DDFE SFWLSNTCR LHCLKQYSG+EGFM NT++QNEHCL NFDL EYRQVLSDL+IQ
Sbjct: 1549 DDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQ 1608
Query: 1601 IYQQLIKIAEGVLQPMIVSAMLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQ 1660
IYQQL+++ E +LQPMIVS MLE+E+IQG+SGVKPTG RKR+SS+AD + +Y L++I+RQ
Sbjct: 1609 IYQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIAD-EGTYTLDSILRQ 1667
Query: 1661 MNAFHTVMCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLE 1720
+N+FH+VMC G+DPE+I QV KQ+FY+I A+TLNNLLLRKD+CSWS GMQ+RYN+SQLE
Sbjct: 1668 LNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLE 1727
Query: 1721 EWLRGRNLHQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYT 1780
EWLR +NL SGA +T+EPLIQAAQLLQ+KKKT +DAEAICS+C +L+T QIVK+LNLYT
Sbjct: 1728 EWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYT 1787
Query: 1781 PLNEFEERVTVAFIRTIQAQLQERNDPQQLLLDAKHMFPVLFPFNPSSLTMDSIHIPACL 1840
P+NEFEERV+V+FIRTIQ +L++R D QLL+DAKH+FPV FPFNPSSL +++I IPA L
Sbjct: 1788 PVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASL 1847
Query: 1841 NLEFLNEV 1848
L F++ V
Sbjct: 1848 GLGFISRV 1855
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 2269 bits (5879), Expect = 0.0
Identities = 1160/1867 (62%), Positives = 1442/1867 (77%), Gaps = 58/1867 (3%)
Query: 1 MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLP 60
M+ ELY++ RVWIPDP+EVW+SAEL KDYK GDK L L LE+ LEY +D + +LP
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELP 60
Query: 61 FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYG 120
LRNPDILVGENDLTALSYLHEPAVLHNL+VRF++S IYTYCGIVLVAINPYEQLPIYG
Sbjct: 61 HLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYG 120
Query: 121 QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF 180
+D+I YSGQNMGDMDPHIFAVAEEAYKQMARDE+NQSIIVSGESGAGKTVSAKYAMRYF
Sbjct: 121 EDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYF 180
Query: 181 ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240
ATV GSASE N+EEKVLAS+PIME+IGNAKTTRNDNSSRFGKYI+IGFDKRY IIGANMR
Sbjct: 181 ATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMR 240
Query: 241 TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD 300
TYLLEKSRVVFQA++ERNYHIFYQLCA+A LPEFK L L +A++F YT QGG IEGVD
Sbjct: 241 TYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVD 300
Query: 301 DAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSN 360
DA++ TRQA TLLG+ ESHQM IF+I+A ILHLG+V RD DSC+I P+ L
Sbjct: 301 DAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCI 359
Query: 361 FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI 420
FC L+GV++ +M HWLCHRKL T +ETY+K +S Q NAR+ALAKHIYA+LF WIV+++
Sbjct: 360 FCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNV 419
Query: 421 NKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480
N+ALH+++KQHSFIGVLDIYGFETFE+NSFEQFCINYANEKLQQQFN HVFKLEQEEYMK
Sbjct: 420 NQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 479
Query: 481 EQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQ 539
EQIPWTLIDFYDNQPCI+LIE+KLGILDLLDEECK+PKGTD WAQKLY+ H + F+
Sbjct: 480 EQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
Query: 540 KPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDK--- 596
KPR+SN AFII HFADKVEY +GFLEKN+DTV+EEQI +LK+SKF ++ +LF DD+
Sbjct: 540 KPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAI 599
Query: 597 DPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVR 656
P AT+ G+ ++ + + KEHKKTVGHQFR SLHLLMETLNATTPHYVR
Sbjct: 600 SPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVR 659
Query: 657 CIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKREL 716
CIKPND K PF FD KRAVQQLRACGVLETIRISAAG+PSRW Y +FF+RYRVL+K++++
Sbjct: 660 CIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDV 719
Query: 717 ANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVR 776
+D+K C++VLE LI D DK+QFG+TKIFFRAGQVAYLEKLRADK R A I IQKT+R
Sbjct: 720 L-SDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIR 778
Query: 777 GWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVR 836
GWL + KY R++ A +T+QRY RG+ AR A+ LRR +AA ++QK++RM R+ Y+ R
Sbjct: 779 GWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRR 838
Query: 837 RAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRM 896
A +V+Q++ R R YR++L EHKA IQK VRGW+AR H++R A I +QC FR
Sbjct: 839 AATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRR 898
Query: 897 LKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYT 956
+ A+RELK L+IEARS E K+L++GMENK++QLQRK+DEQNK++K L E+L+ Y
Sbjct: 899 MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
Query: 957 MEVERLKKELVHYQQSPGE-----DTSLRLQEEVESLRTELQRAHSERKILEDAHSREKD 1011
E E+L+ +L Q S E L LQEE+ LR +L++ SE+K +E+ R K
Sbjct: 959 SETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQ 1018
Query: 1012 ELRKRVADLEQENALLKDEKEQLNNQILCQSKD--EFAQNSVKENLMKKELE--EERSRY 1067
E + V++L++EN LLK EKE LN++I+ Q+K+ E + + E + EL+ +ER RY
Sbjct: 1019 ETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078
Query: 1068 QNLVKEYSQLEQRYDNLRDEMTIIKQT--PGHRRNPSNQSSLESDSNYPSISTSEIGDTE 1125
QNL+ E+S+LE+RYD+L++EMT++ PGH+R S SS ES+ I +SEI + E
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE----YIFSSEIAEME 1134
Query: 1126 DALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQ--DSKKVQAEPP 1183
D + EE +K +DM++FLKLQKRV ELEQE++ +Q +L+++E+Q SK + E P
Sbjct: 1135 DIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERP 1194
Query: 1184 QTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLL 1243
Q A+L Y SLKRQELESENKKLKN+LNELRKA+++++ ++ G+P +Y +L
Sbjct: 1195 QI-----RGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAP-AYRVL 1248
Query: 1244 LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA 1303
+ QL EEL+VRKEEVLILR+Q+VS + + P +K+ +
Sbjct: 1249 MEQLTSVSEELDVRKEEVLILRSQLVSQKE---------------AIQPKDDKNTMTDST 1293
Query: 1304 IEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKA 1363
I ED + + GE+ AY GLK+ RLLE+QLQ+Q HE E E L+
Sbjct: 1294 I-----------LLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRG 1342
Query: 1364 QLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKL 1423
++++LKEE ++QQQ Q L L PEA++E +Q EI+RLTNENLDL E +EK +K RKL
Sbjct: 1343 EIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKL 1402
Query: 1424 KKQLKIYMKKAQDLEAAQALAQSERK-RHELNRQVTVQRKEKDFQGMLEYHKEDEALLIR 1482
KKQLK++ KK +LE Q S + E R V + RKEKDFQGMLEY KEDE L++
Sbjct: 1403 KKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVK 1462
Query: 1483 NLVTDLKPQMLS-GTVPCLPAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHND 1541
NL+ +LKP+ ++ +P LPAYIL+MC+RHADY NDD KV SLLTSTIN IKKVLKK D
Sbjct: 1463 NLILELKPRGVAVNLIPGLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGD 1522
Query: 1542 DFEMTSFWLSNTCRLLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQI 1601
DFE SFWLSNTCR LHCLKQYSG+EGFM NT++QNEHCL NFDL EYRQVLSDL+IQI
Sbjct: 1523 DFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQI 1582
Query: 1602 YQQLIKIAEGVLQPMIVSAMLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQM 1661
YQQL+++ E +LQPMIVS MLE+E+IQG+SGVKPTG RKR+SS+AD + +Y L++I+RQ+
Sbjct: 1583 YQQLVRVLENILQPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIAD-EGTYTLDSILRQL 1641
Query: 1662 NAFHTVMCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEE 1721
N+FH+VMC G+DPE+I QV KQ+FY+I A+TLNNLLLRKD+CSWS GMQ+RYN+SQLEE
Sbjct: 1642 NSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEE 1701
Query: 1722 WLRGRNLHQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTP 1781
WLR +NL SGA +T+EPLIQAAQLLQ+KKKT +DAEAICS+C +L+T QIVK+LNLYTP
Sbjct: 1702 WLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTP 1761
Query: 1782 LNEFEERVTVAFIRTIQAQLQERNDPQQLLLDAKHMFPVLFPFNPSSLTMDSIHIPACLN 1841
+NEFEERV+V+FIRTIQ +L++R D QLL+DAKH+FPV FPFNPSSL +++I IPA L
Sbjct: 1762 VNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLG 1821
Query: 1842 LEFLNEV 1848
L F++ V
Sbjct: 1822 LGFISRV 1828
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 1646 bits (4263), Expect = 0.0
Identities = 922/1896 (48%), Positives = 1240/1896 (65%), Gaps = 202/1896 (10%)
Query: 1 MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLP 60
M+V ELY+Q RVWIPDP+EVW+SAE+ KDY+ GDK L+L LED T L+Y ++ + LP
Sbjct: 1 MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPE--SLP 58
Query: 61 FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYG 120
LRNPDILVGENDLTALSYLHEPAVLHNL++RF ES IYTY GI+LVA+NPY+QLPIYG
Sbjct: 59 PLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYG 118
Query: 121 QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF 180
+I+ YSGQNMGDMDPHIFAVAEEAYKQMAR+ +NQSIIVSGESGAGKTVSA+YAMRYF
Sbjct: 119 DAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYF 178
Query: 181 ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240
ATV S S ++E+KVLAS+PI EA+GNAKTTRNDNSSRFGKY +I FD++ IIGANM
Sbjct: 179 ATVSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238
Query: 241 TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD 300
TYLLEKSRVVFQ+++ERNYHIFYQLCA+A EFK L L SAE+F YT GG+T IEGV+
Sbjct: 239 TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVN 298
Query: 301 DAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSN 360
D + +T++ FTLLG KE QM +FKI+A+ILHLG+V I A + S S+S D +L
Sbjct: 299 DRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERS-SVSEDDSHLKV 357
Query: 361 FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI 420
FC LLG+E ++ WLC+RK+VT+SET VK M+ Q +NAR+ALAK IYA LF +IVE I
Sbjct: 358 FCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERI 417
Query: 421 NKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480
N+AL S KQH+FIGVLDIYGFETF+VNSFEQFCINYANEKLQQQFN HVFKLEQEEYMK
Sbjct: 418 NQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 477
Query: 481 EQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQ 539
E IPWTLIDFYDNQP IDLIEAK+GIL+LLDEEC +P GTD+NW QKLY+ + + F+
Sbjct: 478 EDIPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFE 537
Query: 540 KPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPV 599
KPRMSNT+F+I HFADKVEY +GFLEKNRDTVY+ + IL+ASKF L A+ F ++
Sbjct: 538 KPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENP--- 594
Query: 600 PATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIK 659
TP S I+V+SA+ +K ++K + TVG +FR+SL+LLMETLNATTPHYVRCIK
Sbjct: 595 ---TPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIK 651
Query: 660 PNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANT 719
PNDEKLPF FD KR VQQLRACGVLETIRISA YPSRW Y +F++RY +L+ K+EL+ +
Sbjct: 652 PNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFS 711
Query: 720 DKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWL 779
DKK +C+ VL LI+D +++QFG+TKIFFRAGQVAYLEKLR DK R + +M+QK +RGWL
Sbjct: 712 DKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWL 771
Query: 780 QKVKYHRLKGATLTLQRYCRGHLARR---LAEHLRRIRAAVVLQKHYRMQRARQAYQRVR 836
Q+ K+ R + A L +Q+Y RG R A L+ AA+++QKH R R YQ +R
Sbjct: 772 QRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIR 831
Query: 837 RAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRM 896
A + +QA++R RR YR++L EHKA +QK+ R W+ARR FQ +R + IQ +R
Sbjct: 832 MATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYR- 890
Query: 897 LKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYT 956
V +LQ+K+++QNKE L E+L+ +
Sbjct: 891 ------------------------------VQRLQKKLEDQNKENHGLVEKLTSLAALRA 920
Query: 957 MEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKR 1016
+VE+++K L EL++A + R+ E+ R +D + ++
Sbjct: 921 GDVEKIQK-----------------------LEAELEKAATHRRNYEEKGKRYRDAVEEK 957
Query: 1017 VADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELE----EERSRY----- 1067
+A L++ N+ L+ +KEQ+ Q+ Q K E + + +NL K+ + EER R
Sbjct: 958 LAKLQKHNSELETQKEQI--QLKLQEKTEELKEKM-DNLTKQLFDDVQKEERQRMLLEKS 1014
Query: 1068 -----QNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIG 1122
Q+ K+ L++ L+DE ++ S+ E + T
Sbjct: 1015 FELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEF 1074
Query: 1123 DTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEP 1182
+ E L Q ++I +EK +Q + RE+ ++ ++ QL E D + V++
Sbjct: 1075 EKEIELLQAQKIDVEK---------HVQSQKREMREKMSEITKQL--LESYDIEDVRSRL 1123
Query: 1183 PQTDID-LDPNADL--AYNSLKR-----------------QELESENKK---LKNDLNEL 1219
D++ L+ + +L AY LK+ +E+E+ N K L ++N L
Sbjct: 1124 SVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHL 1183
Query: 1220 RKAVADQATQNNSSHGSPD---SYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRL 1276
+K ++ N S S ++++ K ELE +K+++ I ++ ++
Sbjct: 1184 QKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIR----LNEQAEKM 1239
Query: 1277 AGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGL 1336
G+ E + ++ H QE+ +G
Sbjct: 1240 KGKLEELS---------NQLHRSQEE-------------------------------EGT 1259
Query: 1337 KQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQ 1396
++ A L+AQ+ H +E E L +++ ++E D ++ F E++V+ +
Sbjct: 1260 QRKA------LEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQF------ETESEVKCNFR 1307
Query: 1397 QEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMK---KAQDLEAAQALAQSERKRHEL 1453
QE SRLT EN DL+E ++ ++ +KL+ Q+K K KA D+ ++
Sbjct: 1308 QEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSG----------- 1356
Query: 1454 NRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQ-MLSGTVPCLPAYILYMCIRHA 1512
K++ GML+Y +EDEA LI+NL+ DLKP+ ++ +P LPA+IL+MC+R+A
Sbjct: 1357 ---------PKEYLGMLQYKREDEAKLIQNLILDLKPRGVVVNMIPGLPAHILFMCVRYA 1407
Query: 1513 DYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCLKQYSGDEGFMTQ 1572
D ND + SL+ STINGIK+V+K+H +DFEM SFWLSNTC L+CLKQYSG+E FM
Sbjct: 1408 DSLNDANMLKSLMNSTINGIKQVVKEHLEDFEMLSFWLSNTCHFLNCLKQYSGEEEFMKH 1467
Query: 1573 NTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGVLQPMIVSAMLENESIQGLSG 1632
N+ +QN++CL NFDL+EYRQ+LSD++I+IY Q I I E +QP+IV MLE ES+QG+SG
Sbjct: 1468 NSPQQNKNCLNNFDLSEYRQILSDVAIRIYHQFIIIMEKNIQPIIVPGMLEYESLQGISG 1527
Query: 1633 VKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQVFKQLFYMINAV 1692
+KPTG+RKRSSS+ D D Y + ++++Q++ F+T MC GLDPE++ Q KQLF++I AV
Sbjct: 1528 LKPTGFRKRSSSIDDTDG-YTMTSVLQQLSYFYTTMCQNGLDPELVRQAVKQLFFLIGAV 1586
Query: 1693 TLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPLIQAAQLLQLKKK 1752
TLN+L LRKD+CS GMQ+R NIS LEEWL+ +NL S A +T+EPL QAA LLQ+KK
Sbjct: 1587 TLNSLFLRKDMCSCRKGMQIRCNISYLEEWLKDKNLQNSLAKETLEPLSQAAWLLQVKKT 1646
Query: 1753 TQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQLQERNDPQQLLL 1812
T DA+ I CTSLS QI+KILN YTP+++FE+RVT +F+R +QA L R D QL+L
Sbjct: 1647 TDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFEKRVTPSFVRKVQALLNSREDSSQLML 1706
Query: 1813 DAKHMFPVLFPFNPSSLTMDSIHIPACLNLEFLNEV 1848
D K++F V FPF PS ++ I IP+ L FLN +
Sbjct: 1707 DTKYLFQVTFPFTPSPHALEMIQIPSSFKLGFLNRL 1742
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 596 bits (1537), Expect = e-170
Identities = 462/1523 (30%), Positives = 751/1523 (49%), Gaps = 159/1523 (10%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
VW+P + + +A + K+ K + ++L + + D+Q+ NP
Sbjct: 36 VWVPSEKQGFEAASI-KEEKGDEVVVELVENGKKVTVGKDDIQK------MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V +NPY+ LPIY + ++ Y G+
Sbjct: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---ASE 189
+M PHI+A+A+ AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S +
Sbjct: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
Query: 190 TNI----EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLE 245
T+I E+++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+GAN+ TYLLE
Sbjct: 208 TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 246 KSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDF 305
KSR + QA DER +HIFY + A A +L L ++ + S G I D E F
Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEMF 326
Query: 306 EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLL 365
++T +A ++G E Q+SI K+++S+L LG++ + ER+ D S+ P + C L+
Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM-PDNTAAQKVCHLM 385
Query: 366 GVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH 425
G+ + + ++ + K + +Q A ALAK Y +LF WI+ +NKAL
Sbjct: 386 GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
Query: 426 TSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484
+ +Q SF+G+LDI GFE FEVNSFEQ CINY NEKLQQ FN +F LEQEEY +E I
Sbjct: 446 KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
Query: 485 WTLIDF-YDNQPCIDLIEA---KLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK 540
W IDF D QPCI+LIE G+L LLDEEC PK TD+++ +KL S FQK
Sbjct: 506 WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQK 565
Query: 541 PRM--SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598
P+ T F I+H+A KV+Y + +L KN D + + ++L AS VADL+ D
Sbjct: 566 PKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625
Query: 599 VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCI 658
V G +K++ S+ P + K +TVG ++ L LM TL TTP++VRCI
Sbjct: 626 V-----GLDQMAKMT-ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
Query: 659 KPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELA 717
PN EK D ++QLR GVLE IRI G+P+R + +F RY +L
Sbjct: 680 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739
Query: 718 NTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRG 777
D K C +++ L DP+ ++ G++KIFFR G +A+LE+ R K + Q RG
Sbjct: 740 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799
Query: 778 WLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVL--------------- 819
+L + K + A +QR C +L R + R L
Sbjct: 800 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 859
Query: 820 --------------------QKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVR-----RT 854
QKH ++ + Q +A + A M VR +
Sbjct: 860 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 919
Query: 855 YRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAE 914
++L E +A ++ RG + +++ + ++ +A R+ L++E +AE
Sbjct: 920 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ--KLQLEKVTAE 977
Query: 915 -HLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKK--ELVHYQQ 971
+K+L E++++ + + ++ +KE K L E++S T+ E E+ K +L + +
Sbjct: 978 AKIKKL----EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 972 SPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLK--- 1028
S + +RL++E E R EL++ +RK+ DA + +++ADL+ + A LK
Sbjct: 1034 SMISELEVRLKKE-EKSRQELEKL--KRKLEGDA-----SDFHEQIADLQAQIAELKMQL 1085
Query: 1029 DEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEM 1088
+KE+ L + DE AQ + N +K+ +LE +L++++
Sbjct: 1086 AKKEEELQAALARLDDEIAQKN------------------NALKKIRELEGHISDLQEDL 1127
Query: 1089 TIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLK 1148
+ RN + + + ++ T E+ DT D+ +E+ K ++TV K
Sbjct: 1128 ----DSERAARNKAEKQKRDLGEELEALKT-ELEDTLDSTATQQEL-RAKREQEVTVLKK 1181
Query: 1149 L--------QKRVRELEQERKKLQVQL-EKREQQDSKKVQAEPPQTDIDLDPNADLAYN- 1198
+ +V+E+ Q+ + +L E+ EQ K + + ++ + NADLA
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE-NADLAGEL 1240
Query: 1199 ---SLKRQELESENKKLKNDLNELRKAVAD----QATQNNSSHGSPDSYSLLLNQLKLAH 1251
+QE+E + KKL+ + EL+ +D +A N+ H + + L A
Sbjct: 1241 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
Query: 1252 EELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVC 1311
+ ++V L +Q+ + + N++ + E++ Q+ E
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Query: 1312 QTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEE 1371
D + + L+ A +EA L+ ++E+E+L Q E
Sbjct: 1361 NLERHISTLNIQLSDSK-----KKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAA 1414
Query: 1372 MDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERK----LKKQL 1427
DK ++T + +QQE+ L + + ++LV LEK +RK L ++
Sbjct: 1415 YDKLEKT-------------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1428 KIYMKKAQDLEAAQALAQSERKR 1450
I K A + + A+A A+ + +
Sbjct: 1462 NISSKYADERDRAEAEAREKETK 1484
Score = 85.9 bits (211), Expect = 3e-16
Identities = 125/543 (23%), Positives = 240/543 (44%), Gaps = 69/543 (12%)
Query: 925 NKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEE 984
NK + +R + E+ + KT E +T+T + ++E+ +++ E+T + +
Sbjct: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EAQ 1193
Query: 985 VESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKD 1044
V+ +R + +A E + R K L K LE+ENA L E ++L Q+K
Sbjct: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL-----RVLGQAKQ 1248
Query: 1045 EFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQ 1104
E K+ ++ +++E +S+ + + ++L + L++E+ + N +
Sbjct: 1249 EVEH---KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM----LNEAEG 1301
Query: 1105 SSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQ 1164
+++ + S+S S++ DT++ LQ E+ + V KL R+LE+ER LQ
Sbjct: 1302 KAIKLAKDVASLS-SQLQDTQELLQ-------EETRQKLNVSTKL----RQLEEERNSLQ 1349
Query: 1165 VQLEKREQQDSKKVQAEPPQTDIDL-DPNADLAYNSLKRQELESENKKLKNDLNELRKAV 1223
QL++ E + + ++ +I L D L + + LE K+ + ++ L +
Sbjct: 1350 DQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1408
Query: 1224 ADQA--------TQNNSSHGSPDSYSLLLNQLKLAHE-ELEVRKEEVLILRTQIVS---A 1271
++A T+N D L NQ +L E + RK + L+ + +S A
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 1272 DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNS--KTEDWGYLNEDGEL 1329
D+R A A S + E+A+EA + +TN K E ++ ++
Sbjct: 1469 DERDRAEAEAREKETKALSLARA-----LEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1523
Query: 1330 GLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEA 1389
G L++ R LE Q+ E +K QLE L++E+ + +A
Sbjct: 1524 GKNVHELEKSKRALETQM-----------EEMKTQLEELEDELQATE-----------DA 1561
Query: 1390 QVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERK 1449
++ V + + E DL+ E+ E+ R+L++QL Y + +D +ALA + +K
Sbjct: 1562 KLRLEVNMQALKGQFER-DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
Query: 1450 RHE 1452
+ E
Sbjct: 1621 KLE 1623
Score = 80.9 bits (198), Expect = 1e-14
Identities = 151/652 (23%), Positives = 267/652 (40%), Gaps = 98/652 (15%)
Query: 902 ELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE--------QNKEFKTLSEQLSVTTS 953
EL+ L + EH K+ +E +V +LQ K + +K K +E SVT
Sbjct: 1239 ELRVLGQAKQEVEHKKKK---LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1295
Query: 954 TYTMEVERLK-KELVHYQQSPGEDTSLRLQEEVE---SLRTELQRAHSERKILEDAHSRE 1009
E + +K + V S +DT LQEE ++ T+L++ ER L+D E
Sbjct: 1296 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE 1355
Query: 1010 KDELRKRVADLEQENALLKDEKEQLNN-----QILCQSKDEFAQNSVKENLMKKELEEER 1064
+ + + N L D K++L + + L + K F + ENL + + EE+
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI--ENLTQ-QYEEKA 1412
Query: 1065 SRYQNLVKEYSQLEQRYD--------------NLRDEMTIIKQTPGHRRNPSNQSSLESD 1110
+ Y L K ++L+Q D NL + Q +N S++ + E D
Sbjct: 1413 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1472
Query: 1111 SNYPSISTSEIGDT------EDALQQVEEIG----LEKAAMDMTVFLK--LQKRVRELEQ 1158
E E+AL+ EE+ + KA M+ V K + K V ELE+
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1532
Query: 1159 ERKKLQVQLEKREQQDSKKVQAEPPQTD---IDLDPNADLAYNSLKR------QELESEN 1209
++ L+ Q+E+ + Q ++++ E T+ + L+ N +R ++ E +
Sbjct: 1533 SKRALETQMEEMKTQ-LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1591
Query: 1210 KKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL-AHEELEVRKEEVLILRT-Q 1267
++L+ L+E + D+ Q + + L L+L A ++ R+E + LR Q
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 1268 IVSAD-QRRLAGRNAEPNINARSSWPNSEKHVD--------QEDAIEAYHGVCQTNSKTE 1318
D QR L A + ++ N +K QED A Q + + E
Sbjct: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
Query: 1319 DWGYLNEDGELGLAYQG---LKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQ 1375
+ EL + G L+ R LEA++ E EEE +++A + +++ +
Sbjct: 1712 ELAE-----ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 1376 QQTFCQTLLLSPEAQVEFGVQQEISRLTNE------------NLDLKELVEKLEKNERKL 1423
+Q + AQ +Q++ R E K + LE +L
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 1424 KKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKE 1475
++Q++ ++ Q A ++L Q ++K E+ QV +RK M E +KE
Sbjct: 1827 EEQVEQEAREKQ--AATKSLKQKDKKLKEILLQVEDERK------MAEQYKE 1870
Score = 62.0 bits (149), Expect = 5e-09
Identities = 70/369 (18%), Positives = 157/369 (42%), Gaps = 43/369 (11%)
Query: 863 KATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRE--LKALRIEARSAEHLKRLN 920
+A +K + R + +A ++ +MLKA E + + ++ L++
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 921 VGMENKVVQLQRKIDEQNKEFKTLSE---QLSVTTSTYTMEVERLKKELVHYQQSPGEDT 977
+E ++ +++ +++E E + + +L V + ER + + E+
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD----LQARDEQNEEK 1590
Query: 978 SLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE-QENALLKDEKEQLNN 1036
+LQ ++ TEL+ +R + A + + +L+ DLE Q ++ +K +E +
Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQ 1646
Query: 1037 --QILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQT 1094
++ Q KD ++ELE+ R+ + + E++ +L ++ +++
Sbjct: 1647 LRKLQAQMKD-----------FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 1095 PGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR 1154
Q+ LE + +++S G +ALQ + +L+ R+
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSG--RNALQDEKR--------------RLEARIA 1739
Query: 1155 ELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKN 1214
+LE+E ++ Q +E + K Q ++ + N RQ+LE +NK+L++
Sbjct: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1799
Query: 1215 DLNELRKAV 1223
L+E+ AV
Sbjct: 1800 KLHEMEGAV 1808
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 596 bits (1537), Expect = e-170
Identities = 462/1523 (30%), Positives = 751/1523 (49%), Gaps = 159/1523 (10%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
VW+P + + +A + K+ K + ++L + + D+Q+ NP
Sbjct: 36 VWVPSEKQGFEAASI-KEEKGDEVVVELVENGKKVTVGKDDIQK------MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V +NPY+ LPIY + ++ Y G+
Sbjct: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---ASE 189
+M PHI+A+A+ AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S +
Sbjct: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
Query: 190 TNI----EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLE 245
T+I E+++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+GAN+ TYLLE
Sbjct: 208 TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 246 KSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDF 305
KSR + QA DER +HIFY + A A +L L ++ + S G I D E F
Sbjct: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEMF 326
Query: 306 EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLL 365
++T +A ++G E Q+SI K+++S+L LG++ + ER+ D S+ P + C L+
Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM-PDNTAAQKVCHLM 385
Query: 366 GVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH 425
G+ + + ++ + K + +Q A ALAK Y +LF WI+ +NKAL
Sbjct: 386 GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
Query: 426 TSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484
+ +Q SF+G+LDI GFE FEVNSFEQ CINY NEKLQQ FN +F LEQEEY +E I
Sbjct: 446 KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
Query: 485 WTLIDF-YDNQPCIDLIEA---KLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK 540
W IDF D QPCI+LIE G+L LLDEEC PK TD+++ +KL S FQK
Sbjct: 506 WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQK 565
Query: 541 PRM--SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598
P+ T F I+H+A KV+Y + +L KN D + + ++L AS VADL+ D
Sbjct: 566 PKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625
Query: 599 VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCI 658
V G +K++ S+ P + K +TVG ++ L LM TL TTP++VRCI
Sbjct: 626 V-----GLDQMAKMT-ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
Query: 659 KPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELA 717
PN EK D ++QLR GVLE IRI G+P+R + +F RY +L
Sbjct: 680 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739
Query: 718 NTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRG 777
D K C +++ L DP+ ++ G++KIFFR G +A+LE+ R K + Q RG
Sbjct: 740 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799
Query: 778 WLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVL--------------- 819
+L + K + A +QR C +L R + R L
Sbjct: 800 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 859
Query: 820 --------------------QKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVR-----RT 854
QKH ++ + Q +A + A M VR +
Sbjct: 860 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 919
Query: 855 YRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAE 914
++L E +A ++ RG + +++ + ++ +A R+ L++E +AE
Sbjct: 920 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ--KLQLEKVTAE 977
Query: 915 -HLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKK--ELVHYQQ 971
+K+L E++++ + + ++ +KE K L E++S T+ E E+ K +L + +
Sbjct: 978 AKIKKL----EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 972 SPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLK--- 1028
S + +RL++E E R EL++ +RK+ DA + +++ADL+ + A LK
Sbjct: 1034 SMISELEVRLKKE-EKSRQELEKL--KRKLEGDA-----SDFHEQIADLQAQIAELKMQL 1085
Query: 1029 DEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEM 1088
+KE+ L + DE AQ + N +K+ +LE +L++++
Sbjct: 1086 AKKEEELQAALARLDDEIAQKN------------------NALKKIRELEGHISDLQEDL 1127
Query: 1089 TIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLK 1148
+ RN + + + ++ T E+ DT D+ +E+ K ++TV K
Sbjct: 1128 ----DSERAARNKAEKQKRDLGEELEALKT-ELEDTLDSTATQQEL-RAKREQEVTVLKK 1181
Query: 1149 L--------QKRVRELEQERKKLQVQL-EKREQQDSKKVQAEPPQTDIDLDPNADLAYN- 1198
+ +V+E+ Q+ + +L E+ EQ K + + ++ + NADLA
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE-NADLAGEL 1240
Query: 1199 ---SLKRQELESENKKLKNDLNELRKAVAD----QATQNNSSHGSPDSYSLLLNQLKLAH 1251
+QE+E + KKL+ + EL+ +D +A N+ H + + L A
Sbjct: 1241 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
Query: 1252 EELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVC 1311
+ ++V L +Q+ + + N++ + E++ Q+ E
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Query: 1312 QTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEE 1371
D + + L+ A +EA L+ ++E+E+L Q E
Sbjct: 1361 NLERHISTLNIQLSDSK-----KKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAA 1414
Query: 1372 MDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERK----LKKQL 1427
DK ++T + +QQE+ L + + ++LV LEK +RK L ++
Sbjct: 1415 YDKLEKT-------------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
Query: 1428 KIYMKKAQDLEAAQALAQSERKR 1450
I K A + + A+A A+ + +
Sbjct: 1462 NISSKYADERDRAEAEAREKETK 1484
Score = 85.9 bits (211), Expect = 3e-16
Identities = 125/543 (23%), Positives = 240/543 (44%), Gaps = 69/543 (12%)
Query: 925 NKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEE 984
NK + +R + E+ + KT E +T+T + ++E+ +++ E+T + +
Sbjct: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EAQ 1193
Query: 985 VESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKD 1044
V+ +R + +A E + R K L K LE+ENA L E ++L Q+K
Sbjct: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL-----RVLGQAKQ 1248
Query: 1045 EFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQ 1104
E K+ ++ +++E +S+ + + ++L + L++E+ + N +
Sbjct: 1249 EVEH---KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM----LNEAEG 1301
Query: 1105 SSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQ 1164
+++ + S+S S++ DT++ LQ E+ + V KL R+LE+ER LQ
Sbjct: 1302 KAIKLAKDVASLS-SQLQDTQELLQ-------EETRQKLNVSTKL----RQLEEERNSLQ 1349
Query: 1165 VQLEKREQQDSKKVQAEPPQTDIDL-DPNADLAYNSLKRQELESENKKLKNDLNELRKAV 1223
QL++ E + + ++ +I L D L + + LE K+ + ++ L +
Sbjct: 1350 DQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1408
Query: 1224 ADQA--------TQNNSSHGSPDSYSLLLNQLKLAHE-ELEVRKEEVLILRTQIVS---A 1271
++A T+N D L NQ +L E + RK + L+ + +S A
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 1272 DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNS--KTEDWGYLNEDGEL 1329
D+R A A S + E+A+EA + +TN K E ++ ++
Sbjct: 1469 DERDRAEAEAREKETKALSLARA-----LEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1523
Query: 1330 GLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEA 1389
G L++ R LE Q+ E +K QLE L++E+ + +A
Sbjct: 1524 GKNVHELEKSKRALETQM-----------EEMKTQLEELEDELQATE-----------DA 1561
Query: 1390 QVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERK 1449
++ V + + E DL+ E+ E+ R+L++QL Y + +D +ALA + +K
Sbjct: 1562 KLRLEVNMQALKGQFER-DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
Query: 1450 RHE 1452
+ E
Sbjct: 1621 KLE 1623
Score = 80.9 bits (198), Expect = 1e-14
Identities = 151/652 (23%), Positives = 267/652 (40%), Gaps = 98/652 (15%)
Query: 902 ELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE--------QNKEFKTLSEQLSVTTS 953
EL+ L + EH K+ +E +V +LQ K + +K K +E SVT
Sbjct: 1239 ELRVLGQAKQEVEHKKKK---LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1295
Query: 954 TYTMEVERLK-KELVHYQQSPGEDTSLRLQEEVE---SLRTELQRAHSERKILEDAHSRE 1009
E + +K + V S +DT LQEE ++ T+L++ ER L+D E
Sbjct: 1296 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE 1355
Query: 1010 KDELRKRVADLEQENALLKDEKEQLNN-----QILCQSKDEFAQNSVKENLMKKELEEER 1064
+ + + N L D K++L + + L + K F + ENL + + EE+
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI--ENLTQ-QYEEKA 1412
Query: 1065 SRYQNLVKEYSQLEQRYD--------------NLRDEMTIIKQTPGHRRNPSNQSSLESD 1110
+ Y L K ++L+Q D NL + Q +N S++ + E D
Sbjct: 1413 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1472
Query: 1111 SNYPSISTSEIGDT------EDALQQVEEIG----LEKAAMDMTVFLK--LQKRVRELEQ 1158
E E+AL+ EE+ + KA M+ V K + K V ELE+
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1532
Query: 1159 ERKKLQVQLEKREQQDSKKVQAEPPQTD---IDLDPNADLAYNSLKR------QELESEN 1209
++ L+ Q+E+ + Q ++++ E T+ + L+ N +R ++ E +
Sbjct: 1533 SKRALETQMEEMKTQ-LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1591
Query: 1210 KKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL-AHEELEVRKEEVLILRT-Q 1267
++L+ L+E + D+ Q + + L L+L A ++ R+E + LR Q
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 1268 IVSAD-QRRLAGRNAEPNINARSSWPNSEKHVD--------QEDAIEAYHGVCQTNSKTE 1318
D QR L A + ++ N +K QED A Q + + E
Sbjct: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
Query: 1319 DWGYLNEDGELGLAYQG---LKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQ 1375
+ EL + G L+ R LEA++ E EEE +++A + +++ +
Sbjct: 1712 ELAE-----ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 1376 QQTFCQTLLLSPEAQVEFGVQQEISRLTNE------------NLDLKELVEKLEKNERKL 1423
+Q + AQ +Q++ R E K + LE +L
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
Query: 1424 KKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKE 1475
++Q++ ++ Q A ++L Q ++K E+ QV +RK M E +KE
Sbjct: 1827 EEQVEQEAREKQ--AATKSLKQKDKKLKEILLQVEDERK------MAEQYKE 1870
Score = 62.0 bits (149), Expect = 5e-09
Identities = 70/369 (18%), Positives = 157/369 (42%), Gaps = 43/369 (11%)
Query: 863 KATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRE--LKALRIEARSAEHLKRLN 920
+A +K + R + +A ++ +MLKA E + + ++ L++
Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
Query: 921 VGMENKVVQLQRKIDEQNKEFKTLSE---QLSVTTSTYTMEVERLKKELVHYQQSPGEDT 977
+E ++ +++ +++E E + + +L V + ER + + E+
Sbjct: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD----LQARDEQNEEK 1590
Query: 978 SLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE-QENALLKDEKEQLNN 1036
+LQ ++ TEL+ +R + A + + +L+ DLE Q ++ +K +E +
Sbjct: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQ 1646
Query: 1037 --QILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQT 1094
++ Q KD ++ELE+ R+ + + E++ +L ++ +++
Sbjct: 1647 LRKLQAQMKD-----------FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
Query: 1095 PGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR 1154
Q+ LE + +++S G +ALQ + +L+ R+
Sbjct: 1696 LAAAERARKQADLEKEELAEELASSLSG--RNALQDEKR--------------RLEARIA 1739
Query: 1155 ELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKN 1214
+LE+E ++ Q +E + K Q ++ + N RQ+LE +NK+L++
Sbjct: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1799
Query: 1215 DLNELRKAV 1223
L+E+ AV
Sbjct: 1800 KLHEMEGAV 1808
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 594 bits (1531), Expect = e-169
Identities = 461/1530 (30%), Positives = 750/1530 (49%), Gaps = 166/1530 (10%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
VW+P + + +A + K+ K + ++L + + D+Q+ NP
Sbjct: 36 VWVPSEKQGFEAASI-KEEKGDEVVVELVENGKKVTVGKDDIQK------MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V +NPY+ LPIY + ++ Y G+
Sbjct: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATV--------- 183
+M PHI+A+A+ AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V
Sbjct: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
Query: 184 -----GGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGAN 238
G S + +E+++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+GAN
Sbjct: 208 TSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 267
Query: 239 MRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEG 298
+ TYLLEKSR + QA DER +HIFY + A A +L L ++ + S G I
Sbjct: 268 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPA 326
Query: 299 VDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYL 358
D E F++T +A ++G E Q+SI K+++S+L LG++ + ER+ D S+ P +
Sbjct: 327 AQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM-PDNTAA 385
Query: 359 SNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVE 418
C L+G+ + + ++ + K + +Q A ALAK Y +LF WI+
Sbjct: 386 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445
Query: 419 HINKALHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEE 477
+NKAL + +Q SF+G+LDI GFE FEVNSFEQ CINY NEKLQQ FN +F LEQEE
Sbjct: 446 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505
Query: 478 YMKEQIPWTLIDF-YDNQPCIDLIEA---KLGILDLLDEECKVPKGTDQNWAQKLYDRHS 533
Y +E I W IDF D QPCI+LIE G+L LLDEEC PK TD+++ +KL
Sbjct: 506 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 565
Query: 534 SSQHFQKPRM--SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADL 591
S FQKP+ T F I+H+A KV+Y + +L KN D + + ++L AS VADL
Sbjct: 566 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625
Query: 592 FHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATT 651
+ D V G +K++ S+ P + K +TVG ++ L LM TL TT
Sbjct: 626 WKDVDRIV-----GLDQMAKMT-ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTT 679
Query: 652 PHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLV 711
P++VRCI PN EK D ++QLR GVLE IRI G+P+R + +F RY +L
Sbjct: 680 PNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILA 739
Query: 712 KKR-ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIM 770
D K C +++ L DP+ ++ G++KIFFR G +A+LE+ R K +
Sbjct: 740 ANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMA 799
Query: 771 IQKTVRGWLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVL-------- 819
Q RG+L + K + A +QR C +L R + R L
Sbjct: 800 FQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEE 859
Query: 820 ---------------------------QKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVR 852
QKH ++ + Q +A + A M VR
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 919
Query: 853 -----RTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALR 907
+ ++L E +A ++ RG + +++ + ++ +A R+ L+
Sbjct: 920 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ--KLQ 977
Query: 908 IEARSAE-HLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKK-- 964
+E +AE +K+L E++++ + + ++ +KE K L E++S T+ E E+ K
Sbjct: 978 LEKVTAEAKIKKL----EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 965 ELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQEN 1024
+L + +S + +RL++E E R EL++ +RK+ DA + +++ADL+ +
Sbjct: 1034 KLKNKHESMISELEVRLKKE-EKSRQELEKL--KRKLEGDA-----SDFHEQIADLQAQI 1085
Query: 1025 ALLK---DEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRY 1081
A LK +KE+ L + DE AQ + N +K+ +LE
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKN------------------NALKKIRELEGHI 1127
Query: 1082 DNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAM 1141
+L++++ + RN + + + ++ T E+ DT D+ +E+ K
Sbjct: 1128 SDLQEDL----DSERAARNKAEKQKRDLGEELEALKT-ELEDTLDSTATQQEL-RAKREQ 1181
Query: 1142 DMTVFLKL--------QKRVRELEQERKKLQVQL-EKREQQDSKKVQAEPPQTDIDLDPN 1192
++TV K + +V+E+ Q+ + +L E+ EQ K + + ++ + N
Sbjct: 1182 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE-N 1240
Query: 1193 ADLAYN----SLKRQELESENKKLKNDLNELRKAVAD----QATQNNSSHGSPDSYSLLL 1244
ADLA +QE+E + KKL+ + EL+ +D +A N+ H + +
Sbjct: 1241 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 1245 NQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAI 1304
L A + ++V L +Q+ + + N++ + E++ Q+
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 1305 EAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQ 1364
E D + + L+ A +EA L+ ++E+E+L Q
Sbjct: 1361 EEMEAKQNLERHISTLNIQLSDSK-----KKLQDFASTVEA-LEEGKKRFQKEIENLTQQ 1414
Query: 1365 LEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERK-- 1422
E DK ++T + +QQE+ L + + ++LV LEK +RK
Sbjct: 1415 YEEKAAAYDKLEKT-------------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461
Query: 1423 --LKKQLKIYMKKAQDLEAAQALAQSERKR 1450
L ++ I K A + + A+A A+ + +
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETK 1491
Score = 85.9 bits (211), Expect = 3e-16
Identities = 125/543 (23%), Positives = 240/543 (44%), Gaps = 69/543 (12%)
Query: 925 NKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEE 984
NK + +R + E+ + KT E +T+T + ++E+ +++ E+T + +
Sbjct: 1142 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EAQ 1200
Query: 985 VESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKD 1044
V+ +R + +A E + R K L K LE+ENA L E ++L Q+K
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL-----RVLGQAKQ 1255
Query: 1045 EFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQ 1104
E K+ ++ +++E +S+ + + ++L + L++E+ + N +
Sbjct: 1256 EVEH---KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM----LNEAEG 1308
Query: 1105 SSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQ 1164
+++ + S+S S++ DT++ LQ E+ + V KL R+LE+ER LQ
Sbjct: 1309 KAIKLAKDVASLS-SQLQDTQELLQ-------EETRQKLNVSTKL----RQLEEERNSLQ 1356
Query: 1165 VQLEKREQQDSKKVQAEPPQTDIDL-DPNADLAYNSLKRQELESENKKLKNDLNELRKAV 1223
QL++ E + + ++ +I L D L + + LE K+ + ++ L +
Sbjct: 1357 DQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1415
Query: 1224 ADQA--------TQNNSSHGSPDSYSLLLNQLKLAHE-ELEVRKEEVLILRTQIVS---A 1271
++A T+N D L NQ +L E + RK + L+ + +S A
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 1272 DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNS--KTEDWGYLNEDGEL 1329
D+R A A S + E+A+EA + +TN K E ++ ++
Sbjct: 1476 DERDRAEAEAREKETKALSLARA-----LEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1530
Query: 1330 GLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEA 1389
G L++ R LE Q+ E +K QLE L++E+ + +A
Sbjct: 1531 GKNVHELEKSKRALETQM-----------EEMKTQLEELEDELQATE-----------DA 1568
Query: 1390 QVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERK 1449
++ V + + E DL+ E+ E+ R+L++QL Y + +D +ALA + +K
Sbjct: 1569 KLRLEVNMQALKGQFER-DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1627
Query: 1450 RHE 1452
+ E
Sbjct: 1628 KLE 1630
Score = 80.9 bits (198), Expect = 1e-14
Identities = 151/652 (23%), Positives = 267/652 (40%), Gaps = 98/652 (15%)
Query: 902 ELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE--------QNKEFKTLSEQLSVTTS 953
EL+ L + EH K+ +E +V +LQ K + +K K +E SVT
Sbjct: 1246 ELRVLGQAKQEVEHKKKK---LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1302
Query: 954 TYTMEVERLK-KELVHYQQSPGEDTSLRLQEEVE---SLRTELQRAHSERKILEDAHSRE 1009
E + +K + V S +DT LQEE ++ T+L++ ER L+D E
Sbjct: 1303 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE 1362
Query: 1010 KDELRKRVADLEQENALLKDEKEQLNN-----QILCQSKDEFAQNSVKENLMKKELEEER 1064
+ + + N L D K++L + + L + K F + ENL + + EE+
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI--ENLTQ-QYEEKA 1419
Query: 1065 SRYQNLVKEYSQLEQRYD--------------NLRDEMTIIKQTPGHRRNPSNQSSLESD 1110
+ Y L K ++L+Q D NL + Q +N S++ + E D
Sbjct: 1420 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1479
Query: 1111 SNYPSISTSEIGDT------EDALQQVEEIG----LEKAAMDMTVFLK--LQKRVRELEQ 1158
E E+AL+ EE+ + KA M+ V K + K V ELE+
Sbjct: 1480 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1539
Query: 1159 ERKKLQVQLEKREQQDSKKVQAEPPQTD---IDLDPNADLAYNSLKR------QELESEN 1209
++ L+ Q+E+ + Q ++++ E T+ + L+ N +R ++ E +
Sbjct: 1540 SKRALETQMEEMKTQ-LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1598
Query: 1210 KKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL-AHEELEVRKEEVLILRT-Q 1267
++L+ L+E + D+ Q + + L L+L A ++ R+E + LR Q
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 1268 IVSAD-QRRLAGRNAEPNINARSSWPNSEKHVD--------QEDAIEAYHGVCQTNSKTE 1318
D QR L A + ++ N +K QED A Q + + E
Sbjct: 1659 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1718
Query: 1319 DWGYLNEDGELGLAYQG---LKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQ 1375
+ EL + G L+ R LEA++ E EEE +++A + +++ +
Sbjct: 1719 ELAE-----ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 1376 QQTFCQTLLLSPEAQVEFGVQQEISRLTNE------------NLDLKELVEKLEKNERKL 1423
+Q + AQ +Q++ R E K + LE +L
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 1424 KKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKE 1475
++Q++ ++ Q A ++L Q ++K E+ QV +RK M E +KE
Sbjct: 1834 EEQVEQEAREKQ--AATKSLKQKDKKLKEILLQVEDERK------MAEQYKE 1877
Score = 62.0 bits (149), Expect = 5e-09
Identities = 70/369 (18%), Positives = 157/369 (42%), Gaps = 43/369 (11%)
Query: 863 KATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRE--LKALRIEARSAEHLKRLN 920
+A +K + R + +A ++ +MLKA E + + ++ L++
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 921 VGMENKVVQLQRKIDEQNKEFKTLSE---QLSVTTSTYTMEVERLKKELVHYQQSPGEDT 977
+E ++ +++ +++E E + + +L V + ER + + E+
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD----LQARDEQNEEK 1597
Query: 978 SLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE-QENALLKDEKEQLNN 1036
+LQ ++ TEL+ +R + A + + +L+ DLE Q ++ +K +E +
Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQ 1653
Query: 1037 --QILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQT 1094
++ Q KD ++ELE+ R+ + + E++ +L ++ +++
Sbjct: 1654 LRKLQAQMKD-----------FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 1095 PGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR 1154
Q+ LE + +++S G +ALQ + +L+ R+
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSG--RNALQDEKR--------------RLEARIA 1746
Query: 1155 ELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKN 1214
+LE+E ++ Q +E + K Q ++ + N RQ+LE +NK+L++
Sbjct: 1747 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1806
Query: 1215 DLNELRKAV 1223
L+E+ AV
Sbjct: 1807 KLHEMEGAV 1815
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 594 bits (1531), Expect = e-169
Identities = 461/1530 (30%), Positives = 750/1530 (49%), Gaps = 166/1530 (10%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
VW+P + + +A + K+ K + ++L + + D+Q+ NP
Sbjct: 36 VWVPSEKQGFEAASI-KEEKGDEVVVELVENGKKVTVGKDDIQK------MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V +NPY+ LPIY + ++ Y G+
Sbjct: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATV--------- 183
+M PHI+A+A+ AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V
Sbjct: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
Query: 184 -----GGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGAN 238
G S + +E+++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+GAN
Sbjct: 208 TSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 267
Query: 239 MRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEG 298
+ TYLLEKSR + QA DER +HIFY + A A +L L ++ + S G I
Sbjct: 268 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPA 326
Query: 299 VDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYL 358
D E F++T +A ++G E Q+SI K+++S+L LG++ + ER+ D S+ P +
Sbjct: 327 AQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM-PDNTAA 385
Query: 359 SNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVE 418
C L+G+ + + ++ + K + +Q A ALAK Y +LF WI+
Sbjct: 386 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445
Query: 419 HINKALHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEE 477
+NKAL + +Q SF+G+LDI GFE FEVNSFEQ CINY NEKLQQ FN +F LEQEE
Sbjct: 446 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505
Query: 478 YMKEQIPWTLIDF-YDNQPCIDLIEA---KLGILDLLDEECKVPKGTDQNWAQKLYDRHS 533
Y +E I W IDF D QPCI+LIE G+L LLDEEC PK TD+++ +KL
Sbjct: 506 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 565
Query: 534 SSQHFQKPRM--SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADL 591
S FQKP+ T F I+H+A KV+Y + +L KN D + + ++L AS VADL
Sbjct: 566 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625
Query: 592 FHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATT 651
+ D V G +K++ S+ P + K +TVG ++ L LM TL TT
Sbjct: 626 WKDVDRIV-----GLDQMAKMT-ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTT 679
Query: 652 PHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLV 711
P++VRCI PN EK D ++QLR GVLE IRI G+P+R + +F RY +L
Sbjct: 680 PNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILA 739
Query: 712 KKR-ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIM 770
D K C +++ L DP+ ++ G++KIFFR G +A+LE+ R K +
Sbjct: 740 ANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMA 799
Query: 771 IQKTVRGWLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVL-------- 819
Q RG+L + K + A +QR C +L R + R L
Sbjct: 800 FQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEE 859
Query: 820 ---------------------------QKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVR 852
QKH ++ + Q +A + A M VR
Sbjct: 860 EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVR 919
Query: 853 -----RTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALR 907
+ ++L E +A ++ RG + +++ + ++ +A R+ L+
Sbjct: 920 LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ--KLQ 977
Query: 908 IEARSAE-HLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKK-- 964
+E +AE +K+L E++++ + + ++ +KE K L E++S T+ E E+ K
Sbjct: 978 LEKVTAEAKIKKL----EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLT 1033
Query: 965 ELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQEN 1024
+L + +S + +RL++E E R EL++ +RK+ DA + +++ADL+ +
Sbjct: 1034 KLKNKHESMISELEVRLKKE-EKSRQELEKL--KRKLEGDA-----SDFHEQIADLQAQI 1085
Query: 1025 ALLK---DEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRY 1081
A LK +KE+ L + DE AQ + N +K+ +LE
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKN------------------NALKKIRELEGHI 1127
Query: 1082 DNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAM 1141
+L++++ + RN + + + ++ T E+ DT D+ +E+ K
Sbjct: 1128 SDLQEDL----DSERAARNKAEKQKRDLGEELEALKT-ELEDTLDSTATQQEL-RAKREQ 1181
Query: 1142 DMTVFLKL--------QKRVRELEQERKKLQVQL-EKREQQDSKKVQAEPPQTDIDLDPN 1192
++TV K + +V+E+ Q+ + +L E+ EQ K + + ++ + N
Sbjct: 1182 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE-N 1240
Query: 1193 ADLAYN----SLKRQELESENKKLKNDLNELRKAVAD----QATQNNSSHGSPDSYSLLL 1244
ADLA +QE+E + KKL+ + EL+ +D +A N+ H + +
Sbjct: 1241 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 1245 NQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAI 1304
L A + ++V L +Q+ + + N++ + E++ Q+
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 1305 EAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQ 1364
E D + + L+ A +EA L+ ++E+E+L Q
Sbjct: 1361 EEMEAKQNLERHISTLNIQLSDSK-----KKLQDFASTVEA-LEEGKKRFQKEIENLTQQ 1414
Query: 1365 LEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERK-- 1422
E DK ++T + +QQE+ L + + ++LV LEK +RK
Sbjct: 1415 YEEKAAAYDKLEKT-------------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461
Query: 1423 --LKKQLKIYMKKAQDLEAAQALAQSERKR 1450
L ++ I K A + + A+A A+ + +
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETK 1491
Score = 85.9 bits (211), Expect = 3e-16
Identities = 125/543 (23%), Positives = 240/543 (44%), Gaps = 69/543 (12%)
Query: 925 NKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEE 984
NK + +R + E+ + KT E +T+T + ++E+ +++ E+T + +
Sbjct: 1142 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EAQ 1200
Query: 985 VESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKD 1044
V+ +R + +A E + R K L K LE+ENA L E ++L Q+K
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL-----RVLGQAKQ 1255
Query: 1045 EFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQ 1104
E K+ ++ +++E +S+ + + ++L + L++E+ + N +
Sbjct: 1256 EVEH---KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM----LNEAEG 1308
Query: 1105 SSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQ 1164
+++ + S+S S++ DT++ LQ E+ + V KL R+LE+ER LQ
Sbjct: 1309 KAIKLAKDVASLS-SQLQDTQELLQ-------EETRQKLNVSTKL----RQLEEERNSLQ 1356
Query: 1165 VQLEKREQQDSKKVQAEPPQTDIDL-DPNADLAYNSLKRQELESENKKLKNDLNELRKAV 1223
QL++ E + + ++ +I L D L + + LE K+ + ++ L +
Sbjct: 1357 DQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1415
Query: 1224 ADQA--------TQNNSSHGSPDSYSLLLNQLKLAHE-ELEVRKEEVLILRTQIVS---A 1271
++A T+N D L NQ +L E + RK + L+ + +S A
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 1272 DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNS--KTEDWGYLNEDGEL 1329
D+R A A S + E+A+EA + +TN K E ++ ++
Sbjct: 1476 DERDRAEAEAREKETKALSLARA-----LEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1530
Query: 1330 GLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEA 1389
G L++ R LE Q+ E +K QLE L++E+ + +A
Sbjct: 1531 GKNVHELEKSKRALETQM-----------EEMKTQLEELEDELQATE-----------DA 1568
Query: 1390 QVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERK 1449
++ V + + E DL+ E+ E+ R+L++QL Y + +D +ALA + +K
Sbjct: 1569 KLRLEVNMQALKGQFER-DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1627
Query: 1450 RHE 1452
+ E
Sbjct: 1628 KLE 1630
Score = 80.9 bits (198), Expect = 1e-14
Identities = 151/652 (23%), Positives = 267/652 (40%), Gaps = 98/652 (15%)
Query: 902 ELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE--------QNKEFKTLSEQLSVTTS 953
EL+ L + EH K+ +E +V +LQ K + +K K +E SVT
Sbjct: 1246 ELRVLGQAKQEVEHKKKK---LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1302
Query: 954 TYTMEVERLK-KELVHYQQSPGEDTSLRLQEEVE---SLRTELQRAHSERKILEDAHSRE 1009
E + +K + V S +DT LQEE ++ T+L++ ER L+D E
Sbjct: 1303 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE 1362
Query: 1010 KDELRKRVADLEQENALLKDEKEQLNN-----QILCQSKDEFAQNSVKENLMKKELEEER 1064
+ + + N L D K++L + + L + K F + ENL + + EE+
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI--ENLTQ-QYEEKA 1419
Query: 1065 SRYQNLVKEYSQLEQRYD--------------NLRDEMTIIKQTPGHRRNPSNQSSLESD 1110
+ Y L K ++L+Q D NL + Q +N S++ + E D
Sbjct: 1420 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1479
Query: 1111 SNYPSISTSEIGDT------EDALQQVEEIG----LEKAAMDMTVFLK--LQKRVRELEQ 1158
E E+AL+ EE+ + KA M+ V K + K V ELE+
Sbjct: 1480 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1539
Query: 1159 ERKKLQVQLEKREQQDSKKVQAEPPQTD---IDLDPNADLAYNSLKR------QELESEN 1209
++ L+ Q+E+ + Q ++++ E T+ + L+ N +R ++ E +
Sbjct: 1540 SKRALETQMEEMKTQ-LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1598
Query: 1210 KKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL-AHEELEVRKEEVLILRT-Q 1267
++L+ L+E + D+ Q + + L L+L A ++ R+E + LR Q
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 1268 IVSAD-QRRLAGRNAEPNINARSSWPNSEKHVD--------QEDAIEAYHGVCQTNSKTE 1318
D QR L A + ++ N +K QED A Q + + E
Sbjct: 1659 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1718
Query: 1319 DWGYLNEDGELGLAYQG---LKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQ 1375
+ EL + G L+ R LEA++ E EEE +++A + +++ +
Sbjct: 1719 ELAE-----ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 1376 QQTFCQTLLLSPEAQVEFGVQQEISRLTNE------------NLDLKELVEKLEKNERKL 1423
+Q + AQ +Q++ R E K + LE +L
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833
Query: 1424 KKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKE 1475
++Q++ ++ Q A ++L Q ++K E+ QV +RK M E +KE
Sbjct: 1834 EEQVEQEAREKQ--AATKSLKQKDKKLKEILLQVEDERK------MAEQYKE 1877
Score = 62.0 bits (149), Expect = 5e-09
Identities = 70/369 (18%), Positives = 157/369 (42%), Gaps = 43/369 (11%)
Query: 863 KATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRE--LKALRIEARSAEHLKRLN 920
+A +K + R + +A ++ +MLKA E + + ++ L++
Sbjct: 1482 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1541
Query: 921 VGMENKVVQLQRKIDEQNKEFKTLSE---QLSVTTSTYTMEVERLKKELVHYQQSPGEDT 977
+E ++ +++ +++E E + + +L V + ER + + E+
Sbjct: 1542 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD----LQARDEQNEEK 1597
Query: 978 SLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE-QENALLKDEKEQLNN 1036
+LQ ++ TEL+ +R + A + + +L+ DLE Q ++ +K +E +
Sbjct: 1598 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQ 1653
Query: 1037 --QILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQT 1094
++ Q KD ++ELE+ R+ + + E++ +L ++ +++
Sbjct: 1654 LRKLQAQMKD-----------FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1702
Query: 1095 PGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR 1154
Q+ LE + +++S G +ALQ + +L+ R+
Sbjct: 1703 LAAAERARKQADLEKEELAEELASSLSG--RNALQDEKR--------------RLEARIA 1746
Query: 1155 ELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKN 1214
+LE+E ++ Q +E + K Q ++ + N RQ+LE +NK+L++
Sbjct: 1747 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1806
Query: 1215 DLNELRKAV 1223
L+E+ AV
Sbjct: 1807 KLHEMEGAV 1815
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 589 bits (1518), Expect = e-168
Identities = 488/1621 (30%), Positives = 772/1621 (47%), Gaps = 207/1621 (12%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
VWIP + +A + K+ + + ++L + + D+Q+ NP
Sbjct: 36 VWIPSERHGFEAASI-KEERGDEVMVELAENGKKAMVNKDDIQK------MNPPKFSKVE 88
Query: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
D+ L+ L+E +VLHNLK R+ S IYTY G+ V INPY+ LPIY +++I Y G+
Sbjct: 89 DMAELTCLNEASVLHNLKDRYY-SGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---ASE 189
+M PHI+A++E AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S +
Sbjct: 148 HEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRKD 207
Query: 190 TNI----EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLE 245
NI E ++L ++PI+E+ GNAKT +NDNSSRFGK+I+I FD +I+GAN+ TYLLE
Sbjct: 208 HNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
Query: 246 KSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDF 305
KSR V QA DER +HIFYQL + AG +L L ++ + S G I G D ++F
Sbjct: 268 KSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLS-NGYIPIPGQQDKDNF 326
Query: 306 EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLL 365
++T +A ++G +S+ K+++S+L G+++ + ER+ D S+ P++ C LL
Sbjct: 327 QETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASM-PENTVAQKLCHLL 385
Query: 366 GVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH 425
G+ + + ++ + K + +Q A ALAK Y +LF W+V INKAL
Sbjct: 386 GMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALD 445
Query: 426 TSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484
+ +Q SFIG+LDI GFE FE+NSFEQ CINY NEKLQQ FN +F LEQEEY +E I
Sbjct: 446 RTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
Query: 485 WTLIDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK 540
W IDF D QPCIDLIE G+L LLDEEC PK TD+ + +KL S FQK
Sbjct: 506 WNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQK 565
Query: 541 PRM--SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598
PR F I+H+A KV+Y +D +L KN D + + +L S VA+L+ D D
Sbjct: 566 PRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELW-KDVDR 624
Query: 599 VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCI 658
+ G + +A + K +TVG ++ SL LM TL T P++VRCI
Sbjct: 625 IVGLDQVTGMT-----ETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCI 679
Query: 659 KPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELA 717
PN EK DP + QLR GVLE IRI G+P+R + +F RY +L
Sbjct: 680 IPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKG 739
Query: 718 NTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRG 777
D K C ++ L DP+ ++ G++KIFFRAG +A+LE+ R K I Q RG
Sbjct: 740 FMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRG 799
Query: 778 WLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQR 834
+L + K + A LQR C +L R + R L + R + QA
Sbjct: 800 YLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQA--- 856
Query: 835 VRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAF 894
+ + ++ K T ++ + M R+H Q L + I+ +
Sbjct: 857 ------------------KDEELLKVKEKQTKVEGELEE-MERKHQQLLEEKNILAE--- 894
Query: 895 RMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTST 954
L+A EL A E R+ K+ +E + L+ +++E+ + + L + +
Sbjct: 895 -QLQAETELFAEAEEMRARLAAKKQE--LEEILHDLESRVEEEEERNQILQNEKKKMQAH 951
Query: 955 YTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHS---REKD 1011
E+L +E E +LQ E + ++++ E +LED +S +EK
Sbjct: 952 IQDLEEQLDEE---------EGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002
Query: 1012 ELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKE------------ 1059
+ R+A+ + L +E+E+ N ++K E + ++E L K+E
Sbjct: 1003 LMEDRIAECSSQ---LAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059
Query: 1060 LEEERSRYQNLVKEYS--------QLEQRYDNLRDEMTIIKQTPGHRRNPSN-------- 1103
L+ E + Q+ + E QL ++ + L+ + H+ N
Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQ 1119
Query: 1104 ----QSSLESDS---NYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE- 1155
Q ES+ N ++ + +AL+ E L+ A + K ++ V E
Sbjct: 1120 IAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAEL 1179
Query: 1156 ---LEQERKKLQVQL---------------EKREQQDSKKVQAEPPQTDIDLDPNADLA- 1196
LE+E K + Q+ E+ EQ K E + ++ D N +LA
Sbjct: 1180 KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETD-NKELAC 1238
Query: 1197 -YNSLKRQELESENKKLKND--LNELRKAVA-------DQATQNNSSHGSPDSYSLLL-- 1244
L++ + ESE+K+ K D + EL V+ + A + + D+ S LL
Sbjct: 1239 EVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEE 1298
Query: 1245 ----------------NQLKLAHEELEVRKEEVLILRTQIVSADQRR-----------LA 1277
+QL+ E L+ + L L ++I ++ + A
Sbjct: 1299 AEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEA 1358
Query: 1278 GRNAEPNINA-RSSWPNSEKHVDQE-DAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQG 1335
+N E + A +S +++K VD + IE+ + K + E LAY
Sbjct: 1359 RKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAE-ALSQRLEEKALAYDK 1417
Query: 1336 LKQVARLLEAQLQ--AQSLEHEEEV-----------EHLKAQ--------------LEAL 1368
L++ L+ +L L+H+ +V + L A+ EA
Sbjct: 1418 LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAE 1477
Query: 1369 KEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENL-----DLKELVEKLEKNERKL 1423
E + + + + L + EA+ EF Q + R E+L D+ + V +LEK++R L
Sbjct: 1478 AREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRAL 1537
Query: 1424 KKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRN 1483
++Q++ + ++LE + + R E+N Q + E+D Q E ++E + LLI+
Sbjct: 1538 EQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ 1597
Query: 1484 L 1484
+
Sbjct: 1598 V 1598
Score = 72.4 bits (176), Expect = 4e-12
Identities = 141/681 (20%), Positives = 277/681 (40%), Gaps = 137/681 (20%)
Query: 895 RMLKARRELKALRIEARSAE-HLK-----RLNVGMENKVVQLQRKIDEQN---------- 938
+ +KA E K +++A+ E H K RL V + K +LQ ++D +
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 939 ----KEFKTLSEQLSVTTSTYTME----------VERLKKELVHYQQSPGEDTSLRLQEE 984
K+ +L QL T E + +L++E Q+ E+ R E
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLE 1363
Query: 985 VESLRTELQRAHSERKILEDAHSRE--KDELRKRVADLE------QENALLKDEKEQLNN 1036
+ L + Q A +++K+ +D + E ++ +K + D E +E AL D+ E+ N
Sbjct: 1364 KQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKN 1423
Query: 1037 QILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTII---KQ 1093
+ L Q D+ + + + LE+++ ++ L+ E + RY RD K+
Sbjct: 1424 R-LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKE 1482
Query: 1094 TPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRV 1153
T + + +LE+ + + D ED + +++G +L+K
Sbjct: 1483 TKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVH--------ELEKSK 1534
Query: 1154 RELEQERKKLQVQLEKREQQ-----DSK-----KVQAEPPQTDIDLDPNAD--------- 1194
R LEQ+ ++++ QLE+ E + D+K +QA Q + DL +
Sbjct: 1535 RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLL 1594
Query: 1195 -------------------LAYNSLKRQEL---------ESENKKLKNDLNELRKAVADQ 1226
LA S K+ E+ E+ NK + +LRK A
Sbjct: 1595 IKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1654
Query: 1227 ATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNI- 1285
+ S + Q K + ++L+ + E+L L+ ++ S+++ R +
Sbjct: 1655 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
Query: 1286 -NARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTE--DWGYLNE------------DGELG 1330
+S +D++ +EA + + E + LN+ + EL
Sbjct: 1715 DEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1774
Query: 1331 L----------AYQGLKQVARLLEAQLQ----AQSLEHEEEVEHLKAQLEALKEEMDKQ- 1375
A Q L++ + L+A+LQ A + + + L+A++ L+E+++++
Sbjct: 1775 AERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA 1834
Query: 1376 -QQTFCQTLLLSPEAQV-EFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKK 1433
++ L+ E ++ E +Q E R + KE +EK ++LK+QL ++
Sbjct: 1835 KERAAANKLVRRTEKKLKEIFMQVEDERRHADQY--KEQMEKANARMKQLKRQL----EE 1888
Query: 1434 AQDLEAAQALAQSERKRHELN 1454
A++ EA +A A + + EL+
Sbjct: 1889 AEE-EATRANASRRKLQRELD 1908
Score = 60.5 bits (145), Expect = 2e-08
Identities = 82/393 (20%), Positives = 153/393 (38%), Gaps = 80/393 (20%)
Query: 877 RRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE 936
++ F +L I + + R E +A E ++ + L +E K + +
Sbjct: 1450 QKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK-----EEFER 1504
Query: 937 QNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAH 996
QNK+ + E L + V L+K + L+++VE +RT+L+
Sbjct: 1505 QNKQLRADMEDLMSSKDDVGKNVHELEK------------SKRALEQQVEEMRTQLEELE 1552
Query: 997 SERKILEDAHSR--------------------EKDELRKR--VADLEQENALLKDEKEQL 1034
E + EDA R E++E +KR + + + A L+DE++Q
Sbjct: 1553 DELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQR 1612
Query: 1035 NNQILCQSKDEF----------AQNSVKENLMK-------------KELEEERSRYQNLV 1071
+ + K E A N ++ ++K +ELEE R+ +
Sbjct: 1613 ALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIF 1672
Query: 1072 KEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQV 1131
+ + E++ +L E+ +++ + E D I+ S G
Sbjct: 1673 AQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG--------- 1723
Query: 1132 EEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDP 1191
+ A +D +L+ R+ +LE+E ++ Q +E + +K + + +L
Sbjct: 1724 -----KSALLDEK--RRLEARIAQLEEELEEEQSNMELLNDR-FRKTTLQVDTLNAELAA 1775
Query: 1192 NADLAYNS-LKRQELESENKKLKNDLNELRKAV 1223
A S RQ+LE +NK+LK L EL AV
Sbjct: 1776 ERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808
Score = 45.8 bits (107), Expect = 4e-04
Identities = 62/321 (19%), Positives = 134/321 (41%), Gaps = 56/321 (17%)
Query: 876 ARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKID 935
ARRH ++ RD + A + + AL E R +E ++ QL+ +++
Sbjct: 1702 ARRHAEQERD-----ELADEITNSASGKSALLDEKRR----------LEARIAQLEEELE 1746
Query: 936 EQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRA 995
E+ + L+++ TT ++V+ L EL + + ++ ++ R +L+R
Sbjct: 1747 EEQSNMELLNDRFRKTT----LQVDTLNAELAAERSAA---------QKSDNARQQLERQ 1793
Query: 996 HSERKI-LEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKEN 1054
+ E K L++ K + + ++ LE + L+++ EQ ++K+ A N +
Sbjct: 1794 NKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQ-------EAKERAAANKLVRR 1846
Query: 1055 LMKK------ELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSN---QS 1105
KK ++E+ER ++ + R L+ ++ ++ R N S Q
Sbjct: 1847 TEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEE-ATRANASRRKLQR 1905
Query: 1106 SLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQV 1165
L+ + + E+ ++ L++ I F + R+L E L++
Sbjct: 1906 ELDDATEANEGLSREVSTLKNRLRRGGPIS----------FSSSRSGRRQLHLEGASLEL 1955
Query: 1166 QLEKREQQDSKKVQAEPPQTD 1186
+ E + S + +PPQ++
Sbjct: 1956 SDDDTESKTSDVNETQPPQSE 1976
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 587 bits (1512), Expect = e-167
Identities = 471/1621 (29%), Positives = 771/1621 (47%), Gaps = 210/1621 (12%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
VW+P + A L ++ E + ++L + + D+Q+ NP
Sbjct: 32 VWVPSDKSGFEPASLKEEVGE-EAIVELVENGKKVKVNKDDIQK------MNPPKFSKVE 84
Query: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
D+ L+ L+E +VLHNLK R+ S IYTY G+ V INPY+ LPIY ++++ Y G+
Sbjct: 85 DMAELTCLNEASVLHNLKERYY-SGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKR 143
Query: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS----AS 188
+M PHI+A+ + AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S
Sbjct: 144 HEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKD 203
Query: 189 ETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSR 248
+ +E ++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+GAN+ TYLLEKSR
Sbjct: 204 QGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSR 263
Query: 249 VVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKT 308
+ QA +ER +HIFY L + AG +L L + + S G +I G D + F++T
Sbjct: 264 AIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLS-NGHVTIPGQQDKDMFQET 322
Query: 309 RQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLLGVE 368
+A ++G+ E QM + ++I+ +L LG++ + ER+ D S+ P + LLG+
Sbjct: 323 MEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASM-PDNTAAQKVSHLLGIN 381
Query: 369 HSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSL 428
+ + ++ + K + +Q A ALAK Y ++F W+V INKAL +
Sbjct: 382 VTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTK 441
Query: 429 KQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTL 487
+Q SFIG+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQEEY +E I W
Sbjct: 442 RQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 501
Query: 488 IDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKPRM 543
IDF D QPCIDLIE GIL LLDEEC PK TD+++ +K+ + FQKP+
Sbjct: 502 IDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKPKQ 561
Query: 544 --SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPA 601
F I+H+A KV+Y +D +L KN D + + +L S V++L+ D D +
Sbjct: 562 LKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELW-KDVDRIIG 620
Query: 602 TTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPN 661
G S +A P + K +TVG ++ L LM TL T P++VRCI PN
Sbjct: 621 LDQVAGMS-----ETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPN 675
Query: 662 DEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELANTD 720
EK DP + QLR GVLE IRI G+P+R + +F RY +L D
Sbjct: 676 HEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMD 735
Query: 721 KKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQ 780
K C +++ L D + ++ G++K+FFRAG +A+LE+ R K I Q RG+L
Sbjct: 736 GKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLA 795
Query: 781 K---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRR 837
+ K + A LQR C +L R + R L +Q +RQ + + +
Sbjct: 796 RKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPL-----LQVSRQEEEMMAK 850
Query: 838 AAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCA---- 893
+++ VR +Q+ E++ T ++ MA + + + A CA
Sbjct: 851 EEELVK-------VRE--KQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEE 901
Query: 894 --FRMLKARRELKAL--RIEARSAE------HLKRLNVGMENKVVQLQRKIDEQNKEFKT 943
R+ ++EL+ + +EAR E HL+ M+ + +L+ +++E+ +
Sbjct: 902 LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQK 961
Query: 944 LSEQLSVTTSTYTMEVE-----------RLKKELVHYQQSPGEDTSLRLQEEVESLRTEL 992
L + VTT ++E +L KE + E T+ L EE E ++
Sbjct: 962 LQLE-KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTT-NLTEEEEKSKSLA 1019
Query: 993 QRAHSERKILEDAHSR------EKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEF 1046
+ + ++ D R ++ EL K LE ++ L D+ +L QI + K +
Sbjct: 1020 KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI-AELKMQL 1078
Query: 1047 AQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSS 1106
A+ + +EEE ++ +K+ +LE + L++++ ++ RN + +
Sbjct: 1079 AKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDL----ESERASRNKAEKQK 1134
Query: 1107 LESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQ 1166
+ ++ T E+ DT D+ +E+ K ++ + K LE+E K + Q
Sbjct: 1135 RDLGEELEALKT-ELEDTLDSTAAQQEL-RSKREQEVNILKK------TLEEEAKTHEAQ 1186
Query: 1167 LEKREQQDSKKVQ--AEPPQTDIDLDPNADLAYNSL-----------------------K 1201
+++ Q+ S+ V+ AE + + N + A +L K
Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHK 1246
Query: 1202 RQELESENKKLKNDLNE---LRKAVADQATQ---------------NNSSHGSPDSYSLL 1243
R+++E++ ++L+ NE +R +AD+ T+ ++ S +S L
Sbjct: 1247 RKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL 1306
Query: 1244 LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA 1303
+QL+ E L+ + L L T++ + + + R + KH ++
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFRE-------QLEEEEEAKHNLEKQI 1359
Query: 1304 IEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEV----- 1358
+ V K ED E E +V R L+ L+ S HEE+V
Sbjct: 1360 ATLHAQVADMKKKMEDSVGCLETAE---------EVKRKLQKDLEGLSQRHEEKVAAYDK 1410
Query: 1359 -----EHLKAQLEALKEEMDKQQQTFC--------------------------------- 1380
L+ +L+ L ++D Q+Q+ C
Sbjct: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
Query: 1381 ----QTLLLSPEAQVEFGVQQ-------------EISRLTNENLDLKELVEKLEKNERKL 1423
+T LS +E ++Q E+ L + D+ + V +LEK++R L
Sbjct: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
Query: 1424 KKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRN 1483
++Q++ + ++LE + + R E+N Q + E+D QG E +E + L+R
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 1484 L 1484
+
Sbjct: 1591 V 1591
Score = 77.0 bits (188), Expect = 2e-13
Identities = 121/641 (18%), Positives = 263/641 (41%), Gaps = 51/641 (7%)
Query: 898 KARRELKALRIEARSAEHL----KRLNVGMENKVVQLQ---RKIDEQNKEFKTLSEQLSV 950
K ++ AL + + + L R + + K+ Q++ EQ +E + L
Sbjct: 1298 KLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK 1357
Query: 951 TTSTYTMEVERLKKELVHYQQSPG-----EDTSLRLQEEVESLRTELQRAHSERKILEDA 1005
+T +V +KK++ + S G E+ +LQ+++E L + + LE
Sbjct: 1358 QIATLHAQVADMKKKM---EDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKT 1414
Query: 1006 HSREKDELRKRVADLE--QENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEE 1063
+R + EL + DL+ +++A ++K++ +Q+L + K A+ + + + + E E+
Sbjct: 1415 KTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREK 1474
Query: 1064 RSRYQNLVK----------EYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNY 1113
++ +L + E +L +++ +++ K G + +S +
Sbjct: 1475 ETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQV 1534
Query: 1114 PSISTSEIGDTEDALQQVEE--IGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKRE 1171
+ T ++ + ED LQ E+ + LE M + + R+ + E KK Q+ + RE
Sbjct: 1535 EEMKT-QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593
Query: 1172 QQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNN 1231
+ + + + + ++ L+ ++S NK + +LRK A
Sbjct: 1594 MEAELEDERKQRSMAVAARKKLEMDLKDLEAH-IDSANKNRDEAIKQLRKLQAQMKDCMR 1652
Query: 1232 SSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSW 1291
+ S +L Q K ++L+ + E++ L+ ++ +A++ + + + +
Sbjct: 1653 ELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIAN 1712
Query: 1292 PNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQS 1351
+ + + E+ + Q + E+ E G L LK+ ++ +
Sbjct: 1713 SSGKGALALEEKRRLEARIAQLEEELEE-----EQGNTELINDRLKKANLQIDQINTDLN 1767
Query: 1352 LE--HEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQV---EFGVQQEISRLTNEN 1406
LE H ++ E+ + QLE +E+ + Q T+ +A + E + Q +L NE
Sbjct: 1768 LERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNET 1827
Query: 1407 LDLKELVEKLEKNERKLKKQL--------KIYMKKAQDLEAAQALAQSERKRHELNRQV- 1457
+ + +++ + E+KLK L K Q +A+ L Q +R+ E +
Sbjct: 1828 KERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ 1887
Query: 1458 TVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSGTVP 1498
+ Q LE E + R V+ LK ++ G +P
Sbjct: 1888 RANASRRKLQRELEDATETADAMNRE-VSSLKNKLRRGDLP 1927
Score = 71.6 bits (174), Expect = 7e-12
Identities = 116/532 (21%), Positives = 205/532 (38%), Gaps = 98/532 (18%)
Query: 877 RRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE 936
++ F +L I + + R E +A E ++ + L ME K +++
Sbjct: 1443 QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA-----ELER 1497
Query: 937 QNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAH 996
NK+F+T E L + V L+K + L+++VE ++T+L+
Sbjct: 1498 LNKQFRTEMEDLMSSKDDVGKSVHELEK------------SKRALEQQVEEMKTQLEELE 1545
Query: 997 SERKILEDAHSREKDELRKRVA----DLEQENALLKDEKEQLNNQIL---CQSKDEFAQN 1049
E + EDA R + L+ A DL+ + +++K+QL Q+ + +DE Q
Sbjct: 1546 DELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQR 1605
Query: 1050 SV------KENLMKKELEEE-RSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRN-- 1100
S+ K + K+LE S +N + QL + ++D M + T R
Sbjct: 1606 SMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEIL 1665
Query: 1101 ---PSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLE----------KAAMDMTVFL 1147
N+ L+S E+ E A +Q ++ E K A+ +
Sbjct: 1666 AQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKR 1725
Query: 1148 KLQKRVRELEQERKKLQVQLEK-REQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELE 1206
+L+ R+ +LE+E ++ Q E ++ +Q + TD++L+ + N RQ+LE
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE-RSHAQKNENARQQLE 1784
Query: 1207 SENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRT 1266
+NK+LK L E+ V S S+ + K+A E ++ E
Sbjct: 1785 RQNKELKVKLQEMEGTVK-----------SKYKASITALEAKIAQLEEQLDNE---TKER 1830
Query: 1267 QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNED 1326
Q RR + + + N+E++ DQ D
Sbjct: 1831 QAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADK----------------------- 1867
Query: 1327 GELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQT 1378
A LKQ+ R LE E EEE + A L+ E++ +T
Sbjct: 1868 -----ASTRLKQLKRQLE--------EAEEEAQRANASRRKLQRELEDATET 1906
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 583 bits (1502), Expect = e-166
Identities = 468/1600 (29%), Positives = 797/1600 (49%), Gaps = 180/1600 (11%)
Query: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
T ++ D E + ++ K ++G +++ ++ T++ P DV + NP
Sbjct: 36 TYCFVVDSKEEYAKGKI-KSSQDGKVTVETE-DNRTLVVKPEDV------YAMNPPKFDR 87
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ L++L+EPAVL+NLK R+ S IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 88 IEDMAMLTHLNEPAVLYNLKDRYT-SWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGK 146
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGG----- 185
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+
Sbjct: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLA 206
Query: 186 ----SASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRT 241
S + +E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++ T
Sbjct: 207 KKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 266
Query: 242 YLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIEGV 299
YLLEKSRV FQ ER+YHIFYQ+ + PE EL L T+ D+ + SQG + + +
Sbjct: 267 YLLEKSRVTFQLKAERSYHIFYQILSNKK-PELIELLLITTNPYDYPFISQG-EILVASI 324
Query: 300 DDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCSIS 352
DDAE+ T A +LG + ++K+ +++H G++ QAE DG ++
Sbjct: 325 DDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTE--VA 382
Query: 353 PQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQL 412
+ YL +G+ S + LC ++ +E K ++ QV +A NAL+K +Y +L
Sbjct: 383 DKTAYL------MGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKL 436
Query: 413 FGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFK 472
F W+V IN+ L T L + FIGVLDI GFE FE NS EQ CIN+ NEKLQQ FN H+F
Sbjct: 437 FLWMVTRINQQLDTKLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFV 496
Query: 473 LEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDR 531
LEQEEY KE I WT IDF D CI+LIE +GI +L+EEC PK TD ++ KLYD+
Sbjct: 497 LEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQ 556
Query: 532 H-SSSQHFQKPRM----SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFP 586
H S +FQKP++ + F ++H+A V+Y G+LEKN+D + E + + + S
Sbjct: 557 HLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNR 616
Query: 587 LVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMET 646
L+A L+ AT K++ + +TV FR +L+ LM
Sbjct: 617 LLAHLY-----ATFATADADSGKKKVAKKKG---------SSFQTVSALFRENLNKLMSN 662
Query: 647 LNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNR 706
L T PH+VRCI PN+ K P + + QLR GVLE IRI G+P+R Y DF R
Sbjct: 663 LRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQR 722
Query: 707 YRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKF 764
YRVL E D K C +L ++ D +++FG TK+FF+AG + LE++R D+
Sbjct: 723 YRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRL 782
Query: 765 RTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYR 824
Q RG+L +V++ ++ ++ +C + R ++ ++ ++
Sbjct: 783 AKLITRTQAVCRGFLMRVEFQKMVQRRESI--FCIQYNIR----SFMNVKHWPWMKLFFK 836
Query: 825 MQRARQAYQRVRRAAVVIQAF--TRAMFVRRTYRQVLMEHKATTI--QKHVRGWMARRHF 880
++ ++ + + A + + F T+ + ++ +E K T+ +K+ +
Sbjct: 837 IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES 896
Query: 881 QRLRDAAIVIQCAFRMLKARRELKA-LRIEARSAEHLKRLNV-------GMENKVVQLQR 932
+ L DA + +++KA+ +L+A ++ AE + +N +E++ +L++
Sbjct: 897 ENLLDAE---ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKK 953
Query: 933 KIDE--------------QNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGED-- 976
ID+ + K L+E+LS T ++ R KK L Q +D
Sbjct: 954 DIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIA-KLTREKKALQEAHQQALDDLQ 1012
Query: 977 -----------TSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENA 1025
T +L+++VE L + L++ R LE + + +L+ L QE+
Sbjct: 1013 AEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLK-----LAQESI 1067
Query: 1026 L-LKDEKEQLNNQILCQSKD-EFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDN 1083
L L+++K+QL+ ++ + KD E+ Q ++ ++E+E++ K+ +L+ R +
Sbjct: 1068 LDLENDKQQLDERL--KKKDFEYCQ-------LQSKVEDEQTLGLQFQKKIKELQARIEE 1118
Query: 1084 LRDEM--------TIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA-----LQQ 1130
L +E+ KQ + R S ++ + + E+ +A +
Sbjct: 1119 LEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRD 1178
Query: 1131 VEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAEPPQTDID- 1188
+EE L+ AM + K V EL ++ LQ +K E++ S+ K++ + + ++
Sbjct: 1179 LEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMES 1238
Query: 1189 ---LDPNADLAYNSLKRQ--ELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLL 1243
N + +L+ Q E +N++++ L+EL + T+ + +
Sbjct: 1239 VSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESI 1298
Query: 1244 LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA 1303
++QL + + + EE L+ Q+ ++ + A +A + + +QE
Sbjct: 1299 VSQLSRSKQAFTQQTEE---LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGK 1355
Query: 1304 IEAYHGVCQTNSKTEDW------GYLNEDGELGLAYQGLKQVARLLEAQLQA-----QSL 1352
E + + NS+ W + EL A + L Q + E Q++A SL
Sbjct: 1356 AELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASL 1415
Query: 1353 EH-----EEEVEHLKAQLE---ALKEEMDKQQQTFCQTL----LLSPEAQVEFGVQQEIS 1400
E + EVE L +E +L +DK+Q+ F + L E+Q E + S
Sbjct: 1416 EKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKES 1475
Query: 1401 R-LTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNR-QVT 1458
R L+ E LK E+ +K++ K ++ DL + +A++ + HEL + +
Sbjct: 1476 RSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADL--TEQIAENGKTIHELEKSRKQ 1533
Query: 1459 VQRKEKDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492
++ ++ D Q LE H+E + L I+ +T +K ++
Sbjct: 1534 IELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEI 1573
Score = 62.8 bits (151), Expect = 3e-09
Identities = 121/580 (20%), Positives = 236/580 (40%), Gaps = 87/580 (15%)
Query: 929 QLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESL 988
+LQR + + N E + T E+E KK+L RLQ+ E
Sbjct: 1357 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ-----------RLQDSEE-- 1403
Query: 989 RTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLK--DEKEQLNNQIL------C 1040
+++ +++ LE R + E+ + D+E+ N+L D+K++ +++L C
Sbjct: 1404 --QVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKC 1461
Query: 1041 QSKDEFAQNSVKENL--------MKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIK 1092
+ + S+KE+ +K EE + + + +E LEQ +L +++
Sbjct: 1462 EESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENG 1521
Query: 1093 QTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKR 1152
+T Q LE ++ +E E ++ I LE + + K+ ++
Sbjct: 1522 KTIHELEKSRKQIELEKADIQLALEEAEAA-LEHEEAKILRIQLELTQVKSEIDRKIAEK 1580
Query: 1153 VRELEQERKKLQ---------VQLEKREQQDS----KKVQAEPPQTDIDLDPNADLAYNS 1199
E+EQ ++ Q + E R + ++ KK++ + + +I L A +
Sbjct: 1581 DEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAET 1640
Query: 1200 LKRQELESENKKLKNDL----------NELRKAVADQATQNNSSHGSPDSYSLLLNQL-- 1247
LK L S +LK+ +L++ +A + N + L Q
Sbjct: 1641 LKH--LRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTER 1698
Query: 1248 --KLAHEELEVRKEEVLILRTQIVS---------ADQRRLAGRNAEPNINARSSWPNSEK 1296
KLA +EL E V +L TQ S D +L + + +AR++ ++K
Sbjct: 1699 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 1758
Query: 1297 HVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEE 1356
AI + + K +D E + L Q +K + L+ Q ++
Sbjct: 1759 ------AITDAAMMAEELKKEQDTSAHLERMKKNLE-QTVKDLQHRLDEAEQLALKGGKK 1811
Query: 1357 EVEHLKAQLEALKEEMDKQQQTFCQTL--LLSPEAQV-EFGVQQEISRLTNENLDLKELV 1413
+++ L+ ++ L+ E++ +Q+ +++ L E +V E Q E R L L++LV
Sbjct: 1812 QIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDR--KNVLRLQDLV 1869
Query: 1414 EKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHEL 1453
+KL+ + K+Q + D +A L + + +HEL
Sbjct: 1870 DKLQVKVKSYKRQ-----AEEADEQANAHLTKFRKAQHEL 1904
Score = 55.8 bits (133), Expect = 4e-07
Identities = 89/357 (24%), Positives = 156/357 (43%), Gaps = 40/357 (11%)
Query: 905 ALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEF-KTLSEQLSVT-----TSTYTME 958
AL E RS RL ME + +++ ++ N++ +TL SV T + +
Sbjct: 1601 ALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDD 1660
Query: 959 VERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVA 1018
R +++L Q + E + LQ EVE LR L++ RK+ E +E + +RV
Sbjct: 1661 ALRGQEDLKE-QLAIVERRANLLQAEVEELRATLEQTERARKLAE----QELLDSNERVQ 1715
Query: 1019 DLEQENALLKDEKEQLNNQIL-CQSKDEFAQNSVK--ENLMKKELEEERSRYQNLVKEY- 1074
L +N L K++L ++ QS+ E A + E KK + + + L KE
Sbjct: 1716 LLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQD 1775
Query: 1075 --SQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVE 1132
+ LE+ NL + ++ HR + + Q +L+ + I + E L+ +
Sbjct: 1776 TSAHLERMKKNLEQTVKDLQ----HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQ 1831
Query: 1133 EIGLEKAAMDMTVFLKLQKRVREL----EQERK---KLQVQLEKRE-QQDSKKVQAEPPQ 1184
+K + K ++RV+EL E++RK +LQ ++K + + S K QAE
Sbjct: 1832 ----KKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAE--- 1884
Query: 1185 TDIDLDPNADLAYNSLKRQELESENKK---LKNDLNELRKAVADQATQNNSSHGSPD 1238
+ D NA L + ELE ++ ++ +N+LR D + H S +
Sbjct: 1885 -EADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE 1940
Score = 37.7 bits (86), Expect = 0.10
Identities = 45/199 (22%), Positives = 89/199 (44%), Gaps = 27/199 (13%)
Query: 896 MLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTY 955
+L + ++ L + S H K+ +E ++QLQ ++++ +++ + E+ +
Sbjct: 1707 LLDSNERVQLLHTQNTSLIHTKKK---LETDLMQLQSEVEDASRDARNAEEKAKKAITDA 1763
Query: 956 TMEVERLKKELVHYQQSPGEDTSL---RLQEEVESLRTELQ-RAHSERKILEDAHSREKD 1011
M E LKKE +DTS R+++ +E +LQ R ++ ++
Sbjct: 1764 AMMAEELKKE---------QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ 1814
Query: 1012 ELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERS---RYQ 1068
+L R+ +LE E L+ E+++ + K E VKE + + EE+R R Q
Sbjct: 1815 KLETRIRELEFE---LEGEQKKNTESVKGLRKYE---RRVKE--LTYQSEEDRKNVLRLQ 1866
Query: 1069 NLVKEYSQLEQRYDNLRDE 1087
+LV + + Y +E
Sbjct: 1867 DLVDKLQVKVKSYKRQAEE 1885
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 583 bits (1502), Expect = e-166
Identities = 449/1508 (29%), Positives = 751/1508 (49%), Gaps = 176/1508 (11%)
Query: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
T ++PD E + A++ +EG K + ET + V+ +Q+ +NP
Sbjct: 35 TECFVPDDKEEFVKAKILS--REGGKVIA-----ETENGKTVTVKEDQV-LQQNPPKFDK 86
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ L++LHEPAVL NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 87 IEDMAMLTFLHEPAVLFNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGK 145
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGG----- 185
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFA++
Sbjct: 146 KRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRG 205
Query: 186 -----SASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240
+A++ +E++++ ++P +EA GNAKT RNDNSSRFGK+I+I F + A++
Sbjct: 206 KKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIE 265
Query: 241 TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAE--DFFYTSQGGDTSIEG 298
TYLLEKSRV+FQ ERNYHIFYQ+ + PE ++ L + D+ + SQG + S+
Sbjct: 266 TYLLEKSRVIFQLKAERNYHIFYQILSNKK-PELLDMLLVTNNPYDYAFVSQG-EVSVAS 323
Query: 299 VDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-QAERDGDSCSISPQDVY 357
+DD+E+ T AF +LG + ++K+ +I+H G++ Q +R+ + +D
Sbjct: 324 IDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDAD 383
Query: 358 LSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIV 417
S + L+G+ + + LCH ++ +E K S+QQV + ALAK +Y ++F W+V
Sbjct: 384 KSAY--LMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMV 441
Query: 418 EHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEE 477
IN L T + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LEQEE
Sbjct: 442 TRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEE 501
Query: 478 YMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSS 535
Y KE I WT IDF D Q CIDLIE +GI+ +L+EEC PK TD + KLYD H S
Sbjct: 502 YKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLYDNHLGKS 561
Query: 536 QHFQKPR----MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADL 591
+FQKPR F ++H+A V+Y G+LEKN+D + E + + + S L+A L
Sbjct: 562 NNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATL 621
Query: 592 FHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATT 651
F T G S K S K S+ + TV R +L+ LM L T
Sbjct: 622 FSS------YATADTGDSGK----SKGGKKKGSSFQ---TVSALHRENLNKLMTNLRTTH 668
Query: 652 PHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVL- 710
PH+VRCI PN+ K P D + QLR GVLE IRI G+P+R Y DF RYR+L
Sbjct: 669 PHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 728
Query: 711 -VKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATI 769
V E D + +L +L D ++++FG TK+FF+AG + LE++R ++
Sbjct: 729 PVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIIT 788
Query: 770 MIQKTVRGWLQKVKYHRL---KGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQ 826
+Q RG L ++++ ++ + A L +Q R + ++ ++ +++++
Sbjct: 789 RMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMG---------VKNWPWMKLYFKIK 839
Query: 827 RARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDA 886
++ + + A + + F R I++ + ARR +
Sbjct: 840 PLLKSAETEKEMATMKEEFGR-------------------IKETLEKSEARRKELEEKMV 880
Query: 887 AIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKI---DEQNKEFKT 943
+++ + L+ + E L + L + + +E KV ++ ++ +E N E
Sbjct: 881 SLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 940
Query: 944 LSEQLSVTTSTYTMEVERLKKEL--VHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKI 1001
+L S +++ L+ L V ++ E+ L EE+ L + + E+K
Sbjct: 941 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKA 1000
Query: 1002 LEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELE 1061
L++AH + D+L+ + ++ N+L K K +L Q+ D+ + +E ++ +LE
Sbjct: 1001 LQEAHQQALDDLQ---VEEDKVNSLSK-SKVKLEQQV-----DDLEGSLEQEKKVRMDLE 1051
Query: 1062 EERSRYQNLVK--EYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTS 1119
+ + + +K + S ++ D L+ E + K+ E D N S
Sbjct: 1052 RAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKK--------------EFDINQ---QNS 1094
Query: 1120 EIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQER------KKLQVQLEKREQQ 1173
+I D +QV + L+K + ++++ ELE ER +KL+ L + ++
Sbjct: 1095 KIED-----EQVLALQLQKKLKENQA--RIEELEEELEAERTARAKVEKLRSDLSRELEE 1147
Query: 1174 DSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSS 1233
S++++ T + ++ N ++ E+E +K++ DL E + +AT
Sbjct: 1148 ISERLEEAGGATSVQIEMN----------KKREAEFQKMRRDLEE--ATLQHEATAAALR 1195
Query: 1234 HGSPDSYSLL---LNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSS 1290
DS + L ++ L+ ++LE K E + + S ++ + + ++
Sbjct: 1196 KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLE 1255
Query: 1291 WPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQ 1350
+E V E+A + + +K + E+GEL + L++ L+ +QL
Sbjct: 1256 DQANEYRVKLEEAQRSLNDFTTQRAKLQ-----TENGELA---RQLEEKEALI-SQLTRG 1306
Query: 1351 SLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTL--------LLSPEAQVEFGVQQEISRL 1402
L + +++E LK QL EE K + L LL + + E + E+ R+
Sbjct: 1307 KLSYTQQMEDLKRQL----EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRV 1362
Query: 1403 ------------TNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQS-ERK 1449
T D + E+LE+ ++KL ++L+ + +EA A S E+
Sbjct: 1363 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ---DAEEAVEAVNAKCSSLEKT 1419
Query: 1450 RHELNRQV 1457
+H L ++
Sbjct: 1420 KHRLQNEI 1427
Score = 67.8 bits (164), Expect = 9e-11
Identities = 126/642 (19%), Positives = 259/642 (40%), Gaps = 112/642 (17%)
Query: 860 MEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELK-ALRIEARSAEH--- 915
+E K I + RG ++ + Q++ D R L+ + K AL +SA H
Sbjct: 1293 LEEKEALISQLTRGKLS--YTQQMEDLK-------RQLEEEGKAKNALAHALQSARHDCD 1343
Query: 916 LKRLNVGMENKV-VQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQ--- 971
L R E + +LQR + + N E + T E+E KK+L Q
Sbjct: 1344 LLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1403
Query: 972 ----------SPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE 1021
S E T RLQ E+E L +++R+++ L
Sbjct: 1404 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL------------------- 1444
Query: 1022 QENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRY 1081
D+K++ ++IL + K ++ ++ + ELE + ++L E +L+ Y
Sbjct: 1445 -------DKKQRNFDKILAEWKQKYEES-------QSELESSQKEARSLSTELFKLKNAY 1490
Query: 1082 DNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQ--VEEIGLEKA 1139
+ + + K R N + Q + + + + E +Q VE++ L+ A
Sbjct: 1491 EESLEHLETFK-----RENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545
Query: 1140 AMDMTVFLKLQK-RVRELEQERKKLQVQLEKR-EQQDSKKVQAEPPQTDIDLDPNADLAY 1197
+ L+ ++ ++ + E +++ ++E++ ++D + QA+ + L
Sbjct: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605
Query: 1198 NSLKRQELESENKKLKNDLNEL-------RKAVADQATQNNSSHGSPDSYSLLLNQLKLA 1250
+ R E+ KK++ DLNE+ + A+ Q S + L+ A
Sbjct: 1606 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1665
Query: 1251 HEELEVRKEEVLIL--RTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYH 1308
+++L KE + I+ R ++ A+ L A RS ++ ++ + ++ H
Sbjct: 1666 NDDL---KENIAIVERRNNLLQAELEEL---RAVVEQTERSRKLAEQELIETSERVQLLH 1719
Query: 1309 G-----VCQTNSKTEDWGYLNEDGELGL-AYQGLKQVAR--LLEAQLQAQSLEHEEEVEH 1360
+ Q D L + E + + ++ A+ + +A + A+ L+ E++
Sbjct: 1720 SQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDT-- 1777
Query: 1361 LKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNE 1420
A LE +K+ M++ + L + + ++ G K+ ++KLE
Sbjct: 1778 -SAHLERMKKNMEQTIKDLQHRLDEAEQIALKGG---------------KKQLQKLEARV 1821
Query: 1421 RKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRK 1462
R+L+ +L+ K+ + E+ + + +SER+ EL Q +K
Sbjct: 1822 RELEGELEAEQKR--NAESVKGMRKSERRIKELTYQTEEDKK 1861
Score = 56.6 bits (135), Expect = 2e-07
Identities = 85/379 (22%), Positives = 169/379 (44%), Gaps = 63/379 (16%)
Query: 898 KARRELKALRIEARSA----------EHLKRLNVGME-NKV-VQLQRKIDEQNKEFKTL- 944
K R++L+ ++E +SA E K L +E N++ +++RK+ E+++E +
Sbjct: 1530 KVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1589
Query: 945 --------SEQLSVTTSTYTM-EVERLKKEL------VHYQQSPGEDTSLRLQEEVESLR 989
S Q S+ T + EV R+KK++ + Q S + Q++V+SL+
Sbjct: 1590 RNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1649
Query: 990 TELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQL------NNQILCQSK 1043
+ L+ + L+DA R D+L++ +A +E+ N LL+ E E+L + ++
Sbjct: 1650 SLLKDTQIQ---LDDA-VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705
Query: 1044 DEFAQNSVKENLMKKE----LEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRR 1099
E + S + L+ + + +++ +L + S++E+ R+ K+
Sbjct: 1706 QELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAA 1765
Query: 1100 NPSNQSSLESDSN-----YPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR 1154
+ + E D++ I D + L + E+I L+ + KL+ RVR
Sbjct: 1766 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQ---KLEARVR 1822
Query: 1155 ELEQE---RKKLQVQLEKREQQDSKKVQAEPPQTD---------IDLDPNADLAYNSLKR 1202
ELE E +K + K ++ ++++ QT+ DL L + KR
Sbjct: 1823 ELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKR 1882
Query: 1203 QELESENKKLKNDLNELRK 1221
Q E+E ++ +L++ RK
Sbjct: 1883 QAEEAE-EQANTNLSKFRK 1900
Score = 35.8 bits (81), Expect = 0.40
Identities = 39/169 (23%), Positives = 73/169 (43%), Gaps = 23/169 (13%)
Query: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNK--------------------EFKTLS 945
L+ E ++ HL+R+ ME + LQ ++DE + E + +
Sbjct: 1771 LKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEA 1830
Query: 946 EQLSVTTSTYTM-EVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILED 1004
EQ S M + ER KEL YQ + LRLQ+ V+ L+ +++ + + E+
Sbjct: 1831 EQKRNAESVKGMRKSERRIKELT-YQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1889
Query: 1005 AHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKE 1053
+ + RK +L++ D E N++ +S+D A+ + +
Sbjct: 1890 QANTNLSKFRKVQHELDEAEE-RADIAESQVNKLRAKSRDIGAKQKMHD 1937
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 582 bits (1499), Expect = e-165
Identities = 458/1587 (28%), Positives = 768/1587 (48%), Gaps = 191/1587 (12%)
Query: 32 KEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGENDLTALSYLHEPAVLHNLKV 91
+E DK + L+D + N F NP D+ +++LHEPAVL+NLK
Sbjct: 55 RENDKVIVKTLDDRML------TLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKE 108
Query: 92 RFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNMGDMDPHIFAVAEEAYKQMA 151
R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+ + PHIF++++ AY+ M
Sbjct: 109 RYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFML 167
Query: 152 RDEKNQSIIVSGESGAGKTVSAKYAMRYFATV---GGSASETN-------IEEKVLASSP 201
D NQSI+++GESGAGKTV+ K ++YFAT+ G ET +E++++ ++P
Sbjct: 168 TDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANP 227
Query: 202 IMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVFQADDERNYHI 261
++EA GNAKT RNDNSSRFGK+I+I F + A++ TYLLEKSRV FQ ER+YHI
Sbjct: 228 LLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHI 287
Query: 262 FYQLCAAAGLPEFKELALTSAE--DFFYTSQGGDTSIEGVDDAEDFEKTRQAFTLLGVKE 319
FYQ+ + PE +L L S DF + SQG + ++ +DD+E+ T A +LG
Sbjct: 288 FYQIMSNKK-PELIDLLLISTNPFDFPFVSQG-EVTVASIDDSEELLATDNAIDILGFSS 345
Query: 320 SHQMSIFKIIASILHLGSVAI-------QAERDGDSCSISPQDVYLSNFCRLLGVEHSQM 372
++ I+K+ +++H G++ QAE DG ++ + YL +G+ ++M
Sbjct: 346 EEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE--VADKAGYL------MGLNSAEM 397
Query: 373 EHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSLKQHS 432
LC ++ +E K ++QQV N+ ALAK +Y ++F W+V IN+ L T +
Sbjct: 398 LKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQY 457
Query: 433 FIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDF-Y 491
FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I W IDF
Sbjct: 458 FIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGM 517
Query: 492 DNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQKPR----MSNT 546
D CI+LIE +GI +L+EEC PK TD ++ KLYD+H S +FQKP+ +
Sbjct: 518 DLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEA 577
Query: 547 AFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPATTPGK 606
F +VH+A V+Y G+L+KN+D + E + + + S L++ LF + A T
Sbjct: 578 HFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLF---SNYAGAETGDS 634
Query: 607 GSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLP 666
G S K + +TV FR +L+ LM L +T PH+VRC+ PN+ K P
Sbjct: 635 GGSKKGGKKKG---------SSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTP 685
Query: 667 FHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR--ELANTDKKAI 724
D + QLR GVLE IRI G+PSR Y DF RYR+L E D K
Sbjct: 686 GVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNA 745
Query: 725 CRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKY 784
+L ++ D ++F+FG TK+FF+AG + LE++R +K T Q RG+L +V++
Sbjct: 746 SEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEF 805
Query: 785 HRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQA 844
++ ++ +C + R ++ + ++++ ++ + + A + +
Sbjct: 806 KKMMERRDSI--FCIQYNIR----SFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKED 859
Query: 845 F--TRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRE 902
F T+ R R+ +E K ++ Q D + +Q E
Sbjct: 860 FERTKEELARSEARRKELEEKMVSL------------LQEKNDLQLQVQ---------SE 898
Query: 903 LKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ---NKEFKTLSEQLSVTTSTYTMEV 959
+ L E L + + +E KV +L +++E+ N E L S+ ++
Sbjct: 899 TENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958
Query: 960 ERLKKEL--VHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDEL---- 1013
+ L+ L V ++ E+ L EE+ +L + + E+K L++AH + D+L
Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEE 1018
Query: 1014 ---------------------------RKRVADLEQENALLKDEKEQLNNQILCQSKDEF 1046
+K ADLE+ L+ + + I+ D
Sbjct: 1019 DKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLEND-- 1076
Query: 1047 AQNSVKENLMKKELE---------EERSRYQNLVKEYSQLEQRYDNLRDEM--------T 1089
+ ++E L KKE E +E+ K+ +L+ R + L +E+
Sbjct: 1077 -KQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAK 1135
Query: 1090 IIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA-----LQQVEEIGLEKAAMDMT 1144
I KQ R S +++ + + E+ +A + +EE L+ A T
Sbjct: 1136 IEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1195
Query: 1145 VFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAEPPQTDIDL----DPNADLAYNS 1199
+ K V EL ++ LQ +K E++ S+ K++ + ++I+ N + +
Sbjct: 1196 LRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRT 1255
Query: 1200 LKRQ--ELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVR 1257
++ Q E+++++++ +++L A TQN + L++QL + + L +
Sbjct: 1256 VEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQ 1315
Query: 1258 KEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKT 1317
EE L+ Q+ + + A +A + + +QE E + + NS+
Sbjct: 1316 LEE---LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEV 1372
Query: 1318 EDW------GYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEH-----EEEVEHLKAQLE 1366
W + EL A + L Q RL EA+ ++ E+ + L+ ++E
Sbjct: 1373 AQWRTKYETDAIQRTEELEEAKKKLAQ--RLQEAEENTETANSKCASLEKTKQRLQGEVE 1430
Query: 1367 ALKEE----------MDKQQQTFCQTLL----LSPEAQVEFGVQQEISR-LTNENLDLKE 1411
L + +DK+Q+ F + L E+Q E Q+ SR L+ E ++
Sbjct: 1431 DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRN 1490
Query: 1412 LVEKLEKNERKLKKQLKIYMKKAQDL-----EAAQALAQSERKRHELNRQVT-VQRKEKD 1465
E++ L+++ K ++ DL E + L ++E+ + + ++ + +Q ++
Sbjct: 1491 AYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEE 1550
Query: 1466 FQGMLEYHKEDEALLIRNLVTDLKPQM 1492
+G LE H+E + L ++ ++ +K ++
Sbjct: 1551 VEGSLE-HEESKILRVQLELSQVKSEL 1576
Score = 40.4 bits (93), Expect = 0.016
Identities = 90/472 (19%), Positives = 176/472 (37%), Gaps = 94/472 (19%)
Query: 914 EHLKRLNVGMENKVVQLQRKIDEQNKEF------KTLSEQ----LSVTTSTYTMEVERLK 963
E L+R N ++ ++ L +I E K K L EQ L V +E +
Sbjct: 1500 ETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEE 1559
Query: 964 KELVHYQQSPGEDTS------LRLQEEVESLRTELQRAHSERKILEDAHSREKDEL---- 1013
+++ Q + S + EE+E L+ QRA + + DA R +++
Sbjct: 1560 SKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLK 1619
Query: 1014 RKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKE 1073
+K DL + L Q+ Q Q +K++ + L++ ++L ++
Sbjct: 1620 KKMEGDLNEMEIQLGHSNRQMAE---TQKHLRTVQGQLKDSQL--HLDDALRSNEDLKEQ 1674
Query: 1074 YSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEE 1133
+ +E+R L +E+ +K +LE +S E+ D D +Q +
Sbjct: 1675 LAIVERRNGLLLEELEEMK------------VALEQTERTRRLSEQELLDASDRVQLLHS 1722
Query: 1134 IGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNA 1193
T + +K+ LE + + Q ++E Q+S+ + + + D A
Sbjct: 1723 --------QNTSLINTKKK---LEADIAQCQAEVE-NSIQESRNAEEKAKKAITDA---A 1767
Query: 1194 DLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEE 1253
+A K Q+ + +++K +L + T + H ++ L L K ++
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNLEQ---------TVKDLQHRLDEAEQLALKGGKKQIQK 1818
Query: 1254 LEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQT 1313
LE R E+ +E V+Q+ EA G +
Sbjct: 1819 LENRVREL-------------------------------ENELDVEQKRGAEALKGAHKY 1847
Query: 1314 NSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQL 1365
K ++ Y E+ + L+ + L+A++++ + EE E QL
Sbjct: 1848 ERKVKEMTYQAEEDHKNIL--RLQDLVDKLQAKVKSYKRQAEEAEEQANTQL 1897
Score = 37.4 bits (85), Expect = 0.14
Identities = 40/166 (24%), Positives = 73/166 (43%), Gaps = 27/166 (16%)
Query: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ--------NKEFKTLSEQLSVTTSTYTM 957
L+ E ++ HL+R+ +E V LQ ++DE K+ + L ++ + +
Sbjct: 1773 LKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDV 1832
Query: 958 E-------------VERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILED 1004
E ER KE+ YQ LRLQ+ V+ L+ +++ S ++ E+
Sbjct: 1833 EQKRGAEALKGAHKYERKVKEMT-YQAEEDHKNILRLQDLVDKLQAKVK---SYKRQAEE 1888
Query: 1005 AHSREKDELR--KRVADLEQENALLKDEKEQLNNQILCQSKDEFAQ 1048
A + +L +RV +E A D E N++ +S+D +Q
Sbjct: 1889 AEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQ 1934
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 580 bits (1495), Expect = e-165
Identities = 486/1635 (29%), Positives = 818/1635 (50%), Gaps = 217/1635 (13%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
V++PD + + A++ +EG K + ET + V+ +Q+ +NP
Sbjct: 37 VFVPDDKQEFVKAKIVS--REGGK-----VTAETEYGKTVTVKEDQV-MQQNPPKFDKIE 88
Query: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
D+ L++LHEPAVL+NLK R+ S IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 89 DMAMLTFLHEPAVLYNLKDRY-GSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKR 147
Query: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGG------- 185
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFA +
Sbjct: 148 SEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKK 207
Query: 186 --SASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYL 243
S + +E++++ ++P +EA GNAKT RNDNSSRFGK+I+I F + A++ TYL
Sbjct: 208 DQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267
Query: 244 LEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAE--DFFYTSQGGDTSIEGVDD 301
LEKSRV+FQ ER+YHIFYQ+ + PE ++ L + D+ + SQG +T++ +DD
Sbjct: 268 LEKSRVIFQLKAERDYHIFYQILSNKK-PELLDMLLITNNPYDYAFISQG-ETTVASIDD 325
Query: 302 AEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCSISPQ 354
AE+ T AF +LG + S++K+ +I+H G++ QAE DG + +
Sbjct: 326 AEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTE--EADK 383
Query: 355 DVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFG 414
YL +G+ + + LCH ++ +E K ++QQVI A ALAK +Y ++F
Sbjct: 384 SAYL------MGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFN 437
Query: 415 WIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLE 474
W+V IN L T + FIGVLDI GFE F+ NSFEQ CIN+ NEKLQQ FN H+F LE
Sbjct: 438 WMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLE 497
Query: 475 QEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH- 532
QEEY KE I WT IDF D Q CIDLIE +GI+ +L+EEC PK TD + KL+D H
Sbjct: 498 QEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHL 557
Query: 533 SSSQHFQKPR----MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLV 588
S +FQKPR F ++H+A V+Y G+L+KN+D + E + + + S L+
Sbjct: 558 GKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLL 617
Query: 589 ADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLN 648
+ LF + GKG + K S +TV R +L+ LM L
Sbjct: 618 STLFANYAGADAPIEKGKGKAKKGS--------------SFQTVSALHRENLNKLMTNLR 663
Query: 649 ATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYR 708
+T PH+VRCI PN+ K P D + QLR GVLE IRI G+P+R Y DF RYR
Sbjct: 664 STHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYR 723
Query: 709 VL----VKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKF 764
+L + + + ++ K A +L +L D ++++FG TK+FF+AG + LE++R ++
Sbjct: 724 ILNPAAIPEGQFIDSRKGA--EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERL 781
Query: 765 RTATIMIQKTVRGWLQKVKYHRL---KGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQK 821
IQ RG L +++Y +L + + L +Q R + ++ ++
Sbjct: 782 SRIITRIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMG---------VKNWPWMKL 832
Query: 822 HYRMQRARQAYQRVRRAAVVIQAFTR---AMFVRRTYRQVLMEHKATTIQ-KHVRGWMAR 877
+++++ ++ +R + A + + FTR A+ R+ L E + +Q K+ +
Sbjct: 833 YFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQ 892
Query: 878 RHFQRLRDA----------AIVIQCAFRMLKARRE----------LKALRIEARSAEHLK 917
L DA I ++ + + R E K ++E +E LK
Sbjct: 893 AEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE-LK 951
Query: 918 RLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGED- 976
R +E + +++++ + K L+E+++ ++ + KK L Q +D
Sbjct: 952 RDIDDLELTLAKVEKEKHATENKVKNLTEEMA-GLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 977 ------------TSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELR---KRVADLE 1021
++L+++V+ L L++ R LE A + + +L+ + + DLE
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 1022 QENALLKD---EKEQLNNQILCQSKDEFAQNSVKENLMK------KELEEE-------RS 1065
+ L + +K+ N + + +DE A S + +K +ELEEE R+
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 1066 RYQNLVKEYS-QLEQRYDNLRD---------EMTIIKQTPGHR-RNPSNQSSLESDSNYP 1114
+ + L + S +LE+ + L + EM ++ + R +++L+ ++
Sbjct: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1190
Query: 1115 SI------STSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLE 1168
++ S +E+G+ D LQ+V++ LEK + L+L +EQ K + LE
Sbjct: 1191 ALRKKHADSVAELGEQIDNLQRVKQ-KLEKEKSEFK--LELDDVTSNMEQ-IIKAKANLE 1246
Query: 1169 K-----REQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAV 1223
K +Q + + +AE Q ++ DL + +R +L++EN +L L+E ++A+
Sbjct: 1247 KMCRTLEDQMNEHRSKAEETQRSVN-----DL---TSQRAKLQTENGELSRQLDE-KEAL 1297
Query: 1224 ADQATQNNSSHGS--PDSYSLLLNQLK----LAHEELEVRKEEVLILR------TQIVSA 1271
Q T+ ++ D L ++K LAH L+ + + +LR T+ +
Sbjct: 1298 ISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAH-ALQSARHDCDLLREQYEEETEAKAE 1356
Query: 1272 DQRRLAGRNAE----------PNINARSSWPNSEKHVDQ-----EDAIEAYHGVCQTNSK 1316
QR L+ N+E I ++K + Q E+A+EA + C + K
Sbjct: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
Query: 1317 TEDWGYLNEDGELGLAYQGLKQVARLLE----------AQLQAQSLEHEEEVEHLKAQLE 1366
T+ NE +L + + A L+ A+ + + E + E+E + +
Sbjct: 1417 TKH-RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1475
Query: 1367 ALKEEMDKQQQTFCQTL-LLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKK 1425
+L E+ K + + ++L L + +Q+EIS LT + + + +LEK ++L+
Sbjct: 1476 SLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEA 1535
Query: 1426 QLKIYMKKAQDLEAAQALAQSE-----RKRHELNR-QVTVQRKEKDFQGMLEYHKEDEAL 1479
+ K+ ++ A LE A+A + E R + E N+ + ++RK + +E K +
Sbjct: 1536 E-KMELQSA--LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLR 1592
Query: 1480 LIRNLVTDLKPQMLS 1494
++ +L T L + S
Sbjct: 1593 VVDSLQTSLDAETRS 1607
Score = 73.2 bits (178), Expect = 2e-12
Identities = 131/645 (20%), Positives = 254/645 (39%), Gaps = 118/645 (18%)
Query: 860 MEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRL 919
++ K I + RG + + Q+L D ++ +KA+ L AR L R
Sbjct: 1291 LDEKEALISQLTRGKLT--YTQQLEDLKRQLE---EEVKAKNALAHALQSARHDCDLLRE 1345
Query: 920 NVGMENKV-VQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQ------- 971
E + +LQR + + N E + T E+E KK+L Q
Sbjct: 1346 QYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVE 1405
Query: 972 ------SPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENA 1025
S E T RLQ E+E L +++R+++ L
Sbjct: 1406 AVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL----------------------- 1442
Query: 1026 LLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLR 1085
D+K++ ++IL + K ++ ++ + ELE + ++L E +L+ Y+
Sbjct: 1443 ---DKKQRNFDKILAEWKQKYEES-------QSELESSQKEARSLSTELFKLKNAYEESL 1492
Query: 1086 DEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTV 1145
+ + K R N + Q + S T ++G + + ++E++ + A M +
Sbjct: 1493 EHLETFK-----RENKNLQEEI-------SDLTEQLGSSGKTIHELEKVRKQLEAEKMEL 1540
Query: 1146 FLKLQKRVRELEQERKK-LQVQLE----------KREQQDSKKVQAEPPQTDIDLDPNAD 1194
L++ LE E K L+ QLE K ++D + QA+ +
Sbjct: 1541 QSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTS 1600
Query: 1195 LAYNSLKRQELESENKKLKNDLNEL-------RKAVADQATQNNSSHGSPDSYSLLLNQL 1247
L + R E KK++ DLNE+ + A+ Q S + L+
Sbjct: 1601 LDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDA 1660
Query: 1248 KLAHEELEVRKEEVLIL--RTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIE 1305
A+++L KE + I+ R ++ A+ L A RS ++ ++ + ++
Sbjct: 1661 VRANDDL---KENIAIVERRNNLLQAELEEL---RAVVEQTERSRKLAEQELIETSERVQ 1714
Query: 1306 AYHG-----VCQTNSKTEDWGYLNEDGELGL-AYQGLKQVAR--LLEAQLQAQSLEHEEE 1357
H + Q D L + E + + ++ A+ + +A + A+ L+ E++
Sbjct: 1715 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQD 1774
Query: 1358 VEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLE 1417
A LE +K+ M++ + L + + ++ G K+ ++KLE
Sbjct: 1775 T---SAHLERMKKNMEQTIKDLQHRLDEAEQIALKGG---------------KKQLQKLE 1816
Query: 1418 KNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRK 1462
R+L+ +L+ K+ + E+ + + +SER+ EL Q RK
Sbjct: 1817 ARVRELENELEAEQKR--NAESVKGMRKSERRIKELTYQTEEDRK 1859
Score = 55.1 bits (131), Expect = 6e-07
Identities = 91/381 (23%), Positives = 165/381 (43%), Gaps = 67/381 (17%)
Query: 898 KARRELKALRIEARSA----------EHLKRLNVGME-NKV-VQLQRKIDEQNKEFKTLS 945
K R++L+A ++E +SA E K L +E N++ +++RK+ E+++E +
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
Query: 946 EQ-LSVTTSTYTM---------EVERLKKEL------VHYQQSPGEDTSLRLQEEVESLR 989
L V S T E R+KK++ + Q S + Q++V+SL+
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
Query: 990 TELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLN-------------N 1036
+ L+ + L+DA R D+L++ +A +E+ N LL+ E E+L
Sbjct: 1648 SLLKDTQIQ---LDDA-VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1703
Query: 1037 QILCQSKDE----FAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIK 1092
Q L ++ + +QN+ N KK+++ + S+ Q V+E Q E R + + I
Sbjct: 1704 QELIETSERVQLLHSQNTSLIN-QKKKMDADLSQLQTEVEEAVQ-ECRNAEEKAKKAITD 1761
Query: 1093 QTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKR 1152
Q + I D + L + E+I L+ + KL+ R
Sbjct: 1762 AAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQ---KLEAR 1818
Query: 1153 VRELEQE---RKKLQVQLEKREQQDSKKVQAEPPQTD---------IDLDPNADLAYNSL 1200
VRELE E +K + K ++ ++++ QT+ DL L +
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878
Query: 1201 KRQELESENKKLKNDLNELRK 1221
KRQ E+E ++ +L++ RK
Sbjct: 1879 KRQAEEAE-EQANTNLSKFRK 1898
Score = 35.0 bits (79), Expect = 0.68
Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 23/160 (14%)
Query: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNK--------------------EFKTLS 945
L+ E ++ HL+R+ ME + LQ ++DE + E + +
Sbjct: 1769 LKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA 1828
Query: 946 EQLSVTTSTYTM-EVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILED 1004
EQ S M + ER KEL YQ LRLQ+ V+ L+ +++ + + E+
Sbjct: 1829 EQKRNAESVKGMRKSERRIKELT-YQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1887
Query: 1005 AHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKD 1044
+ + RK +L++ D E N++ +S+D
Sbjct: 1888 QANTNLSKFRKVQHELDEAEE-RADIAESQVNKLRAKSRD 1926
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 579 bits (1492), Expect = e-164
Identities = 465/1564 (29%), Positives = 768/1564 (49%), Gaps = 153/1564 (9%)
Query: 12 RVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNP--DILV 69
RVW+PD + + AE+ + G +++ + D+ +L V+ +L + P D+L
Sbjct: 76 RVWVPDEQDAYVEAEVKSEATGGRVTVETK--DQKVLM----VREAELQPMNPPRFDLL- 128
Query: 70 GENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSG 129
D+ +++L+E +VLHNL+ R+ IYTY G+ V INPY+ LP+Y V+ Y G
Sbjct: 129 --EDMAMMTHLNEASVLHNLRQRYARWM-IYTYSGLFCVTINPYKWLPVYTASVVAAYKG 185
Query: 130 QNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS--- 186
+ D PHI+AVA+ AY M R+ NQS++++GESGAGKTV+ K ++YFA V
Sbjct: 186 KRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDG 245
Query: 187 --------ASETN--IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIG 236
A++T +E++++ ++P MEA GNAKT RNDNSSRFGK+I+I F +
Sbjct: 246 PGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLAS 305
Query: 237 ANMRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAE--DFFYTSQGGDT 294
A++ +YLLEKSRV+FQ ER+YH++YQ+ + PE +++ L S D+ + SQG T
Sbjct: 306 ADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRK-PELQDMLLLSMNPYDYHFCSQGVIT 364
Query: 295 SIEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGD 347
++ ++D E+ T A +LG + + +KI+ ++LH G++ QAE DG
Sbjct: 365 -VDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGT 423
Query: 348 SCSISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKH 407
+ L+GV + L H ++ +E K S++QV+ A ALAK
Sbjct: 424 ESA--------DKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKA 475
Query: 408 IYAQLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFN 467
Y +LF W+V IN+ L T L + FIGVLDI GFE FE NSFEQ CIN+ NEKLQQ FN
Sbjct: 476 TYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFN 535
Query: 468 SHVFKLEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQ 526
H+F LEQEEY +E I W IDF D QPCIDLIE LGIL +L+EEC PK +D ++
Sbjct: 536 QHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRA 595
Query: 527 KLYDRHS-SSQHFQKPRMS-----NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINIL 580
KLYD H+ S +FQ+PR F +VH+A V Y G+LEKN+D + E + I
Sbjct: 596 KLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIF 655
Query: 581 KASKFPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSL 640
+ S+ L+A L+ + P G K R + ++ HK+ +L
Sbjct: 656 QKSQNRLLATLYENYAGSCSTEPPKSGVKEK---RKKAASFQTVSQLHKE--------NL 704
Query: 641 HLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAY 700
+ LM L AT PH+VRCI PN+ K P D + QLR GVLE IRI G+P+R Y
Sbjct: 705 NKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLY 764
Query: 701 HDFFNRYRVLVKKRELANT--DKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEK 758
DF RYR+L +T D + +L +L D ++QFG TK+FF+AG + LE+
Sbjct: 765 TDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEE 824
Query: 759 LRADKFRTATIMIQKTVRGWLQKVKYHRLKG---ATLTLQRYCRGHLARRLAEHLRRIRA 815
LR + ++Q RG L +++Y RL G A T+Q R A + ++
Sbjct: 825 LRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMK---- 880
Query: 816 AVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLME-HKATTIQKHVRGW 874
+ K + R+ QA + + ++ A+ RQ L E H + T +K+
Sbjct: 881 --LFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLAL 938
Query: 875 MARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGME--NKVVQLQR 932
+ L DA + ++K++ +++E + E +RL E + +R
Sbjct: 939 QLQAEQDNLADAE---ERCHLLIKSK-----VQLEGKVKELSERLEDEEEVNADLAARRR 990
Query: 933 KIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPG--EDTSLRLQEEVESLRT 990
K++++ E K + L +T + E + + ++ + + +++ RL +E ++L+
Sbjct: 991 KLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQE 1050
Query: 991 ELQRAHSERKILED---AHSREKDELRKRVAD----LEQENALLKD-----EKEQLNNQI 1038
Q+A + + ED A ++ K L ++V D LEQE L D K + + ++
Sbjct: 1051 AHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKL 1110
Query: 1039 LCQSKDEFAQN--SVKENLMKKE---------LEEERSRYQNLVKEYSQLEQRYDNLRDE 1087
+S + AQ+ ++E L KK+ +E+E+ + K+ +L+ R + L +E
Sbjct: 1111 TQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEE 1170
Query: 1088 MTIIKQTPGH---RRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIG-----LEKA 1139
+ + +R + + E + G E ++ E+G LE+A
Sbjct: 1171 LEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEA 1230
Query: 1140 AM--DMTVFLKLQKRVR---ELEQERKKLQVQLEKREQQDSK-KVQAEPPQTDIDLDPNA 1193
A+ + TV +K+ EL ++ LQ +K E++ S+ +++ + +++ A
Sbjct: 1231 ALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRA 1290
Query: 1194 DLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEE 1253
+ L R E + + K + EL++ +AD +TQ S LL + + +
Sbjct: 1291 KASAEKLCR-TYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQ 1349
Query: 1254 LEVRK----EEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHG 1309
L K + + LR Q+ + + A +A + + + E E
Sbjct: 1350 LSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRL 1409
Query: 1310 VCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALK 1369
+ + N++ W E + + L++ + L +LQ E EE VE A+ +L
Sbjct: 1410 LSKANAEVAQWRSKYEADAIQRT-EELEEAKKKLALRLQ----EAEEGVEAANAKCSSL- 1463
Query: 1370 EEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKI 1429
E+ + QT + + L E + L + L+ +E+ + E +++++L+
Sbjct: 1464 EKAKLRLQTESEDVTLELER-----ATSAAAALDKKQRHLERALEERRRQEEEMQRELEA 1518
Query: 1430 YMKKAQDL------------EAAQALAQSERKRHELNRQVTVQRKEKDFQG--MLEYHKE 1475
++++ L EA +AL +R+ L +++ + G + E K
Sbjct: 1519 AQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKT 1578
Query: 1476 DEAL 1479
+AL
Sbjct: 1579 KKAL 1582
Score = 63.5 bits (153), Expect = 2e-09
Identities = 137/590 (23%), Positives = 241/590 (40%), Gaps = 105/590 (17%)
Query: 929 QLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESL 988
+LQR + + N E + T E+E KK+L +LRLQE E +
Sbjct: 1405 ELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKL-----------ALRLQEAEEGV 1453
Query: 989 RTELQRAHSERKILEDAHSREKDELRKRVADLEQEN--ALLKDEKEQLNNQILCQSKDEF 1046
+ A+++ LE A R + E +LE+ A D+K++ + L + + +
Sbjct: 1454 ----EAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ- 1508
Query: 1047 AQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSS 1106
E M++ELE + + L E +L ++ + + +K R N + Q
Sbjct: 1509 ------EEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLK-----RENKNLQEE 1557
Query: 1107 LESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQ 1166
+ ++ S+S I + E + LE ++ L+ + ELE E K L++Q
Sbjct: 1558 ISDLTDQVSLSGKSIQELEKTKK-----ALEGEKSEIQAALEEAEGALELE-ETKTLRIQ 1611
Query: 1167 LEKRE-QQDSKKVQAEPPQTDIDLDPNADLAYNSLK---------RQELESENKKLKNDL 1216
LE + + + + AE + +L N A SL+ R E KK++ DL
Sbjct: 1612 LELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDL 1671
Query: 1217 NEL--------RKAVADQAT------QNNSSHGSPDSYSLLLNQLKLAHEELEVRKE--- 1259
N+L R+A QA Q D L +L + LE R
Sbjct: 1672 NDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLA 1731
Query: 1260 -EVLILRTQIVSADQ-RRLAGRN---AEPNINARSSWP----NSEKHVD----------Q 1300
E+ LR + ++ RRLA + A +N S N +K ++ +
Sbjct: 1732 AELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVE 1791
Query: 1301 EDAIEAYHGVCQTNSKTEDWGYLNED--------GELGLAYQGLKQVARLLEAQL----Q 1348
E A E + D + E+ L + L+Q R L+A+L Q
Sbjct: 1792 EAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQ 1851
Query: 1349 AQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTL--LLSPEAQV-EFGVQQEISRLTNE 1405
A +++V+ L+A++ L+ E+D +Q+ + L + E +V E Q E R +
Sbjct: 1852 AALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDR---K 1908
Query: 1406 NLD-LKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELN 1454
NL +++LV+KL+ + K+Q + + +A LA+ + +HEL+
Sbjct: 1909 NLARMQDLVDKLQSKVKSYKRQF-----EEAEQQANTNLAKYRKAQHELD 1953
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 575 bits (1481), Expect = e-163
Identities = 463/1593 (29%), Positives = 775/1593 (48%), Gaps = 166/1593 (10%)
Query: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
T V++ +P E + + T KEG K + ++ E L V+ +Q+ F NP
Sbjct: 38 TSVFVAEPKESY--VKSTIQSKEGGK-VTVKTEGGATLT----VREDQV-FPMNPPKYDK 89
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ +++LHEP VL+NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 90 IEDMAMMTHLHEPGVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGK 148
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+ + +
Sbjct: 149 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 208
Query: 191 N---------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRT 241
+E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++ T
Sbjct: 209 KDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
Query: 242 YLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIEGV 299
YLLEKSRV FQ ER+YHIFYQ+ + P+ E+ L T+ D+ + SQG + ++ +
Sbjct: 269 YLLEKSRVTFQLKAERSYHIFYQITSNKK-PDLIEMLLITTNPYDYAFVSQG-EITVPSI 326
Query: 300 DDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCSIS 352
DD E+ T A +LG ++SI+K+ +++H G++ QAE DG ++
Sbjct: 327 DDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE--VA 384
Query: 353 PQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQL 412
+ YL + + + + LC+ ++ +E K ++QQV NA ALAK +Y ++
Sbjct: 385 DKAAYLQS------LNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKM 438
Query: 413 FGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFK 472
F W+V IN+ L T + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+F
Sbjct: 439 FLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFV 498
Query: 473 LEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDR 531
LEQEEY KE I WT IDF D CI+LIE LGI +L+EEC PK TD ++ KLYD+
Sbjct: 499 LEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQ 558
Query: 532 H-SSSQHFQKPRM----SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFP 586
H S +FQKP++ + F ++H+A V+Y G+L+KN+D + + + + + S
Sbjct: 559 HLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMK 618
Query: 587 LVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMET 646
+A LF ++ KG+ K S +TV FR +L+ LM
Sbjct: 619 TLASLFSTYASAEADSSAKKGAKKKGS--------------SFQTVSALFRENLNKLMTN 664
Query: 647 LNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNR 706
L +T PH+VRCI PN+ K P + + + QLR GVLE IRI G+PSR Y DF R
Sbjct: 665 LRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQR 724
Query: 707 YRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKF 764
Y+VL E D K +L ++ D +++FG TK+FF+AG + LE++R +K
Sbjct: 725 YKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKL 784
Query: 765 RTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYR 824
Q RG+L +V+Y ++ LQR + ++ ++ ++
Sbjct: 785 AQIITRTQAVCRGFLMRVEYQKM------LQRREALFCIQYNVRAFMNVKHWPWMKLFFK 838
Query: 825 MQRARQAYQRVRRAAVVIQAF--TRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQR 882
++ ++ + + A + + F T+ + ++ +E K T+ K + +
Sbjct: 839 IKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEA 898
Query: 883 LRDAAIVIQCAFRMLKARRELKA-LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEF 941
A +C +++K + +L+A ++ AE + +N + K +RK++++ E
Sbjct: 899 DSLADAEERCE-QLIKNKIQLEAKIKEVTERAEEEEEINAELTAK----KRKLEDECSEL 953
Query: 942 KTLSEQLSVTTSTYTME-------VERLKKELVHYQQSPGEDTSLR--LQEEVESLRTEL 992
K + L +T + E V+ L +E+ ++ + + + LQE + +L
Sbjct: 954 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDL 1013
Query: 993 QRAHSERKILEDAHSREKDELRKRVADLEQENAL---LKDEKEQLNNQI-LCQSKDEFAQ 1048
Q + IL A ++ + ++ LEQE L L+ K +L + L Q +
Sbjct: 1014 QAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDME 1073
Query: 1049 N---SVKENLMKKE---------LEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPG 1096
N + E L KKE +E+E++ L K+ +L+ R + L +E I +
Sbjct: 1074 NDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEE--IEAERAS 1131
Query: 1097 HRRNPSNQSSLESDSNYPSISTSEIGDTEDA---------------LQQVEEIGLEKAAM 1141
+ +S L + S E G A + +EE L+ AM
Sbjct: 1132 RAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAM 1191
Query: 1142 DMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADL---AYN 1198
+ K + EL ++ LQ R +Q +K ++E DL NA+ A
Sbjct: 1192 VAALRKKHADSMAELGEQIDNLQ-----RVKQKLEKEKSELKMETDDLSSNAEAISKAKG 1246
Query: 1199 SLKR--QELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256
+L++ + LE + +LK E ++ + D Q YS L++ +L
Sbjct: 1247 NLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSR 1306
Query: 1257 RK----EEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQ 1312
K +++ L+ Q+ + + A +A + + +QE E + +
Sbjct: 1307 SKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSK 1366
Query: 1313 TNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEE- 1371
NS+ W E + + L++ + L +LQ ++ EH E V A LE K+
Sbjct: 1367 ANSEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQ-EAEEHVEAVNAKCASLEKTKQRL 1424
Query: 1372 --------------------MDKQQQTFCQTL----LLSPEAQVEFGVQQEISR-LTNEN 1406
+DK+Q+ F + L E Q E Q+ SR L+ E
Sbjct: 1425 QNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL 1484
Query: 1407 LDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNR-QVTVQRKEKD 1465
+K + E+ L+++ K ++ DL + +A+ ++ HEL + + V++++ +
Sbjct: 1485 FKVKNVYEESLDQLETLRRENKNLQQEISDL--TEQIAEGGKQIHELEKIKKQVEQEKCE 1542
Query: 1466 FQGMLE------YHKEDEALLIRNLVTDLKPQM 1492
Q LE H+E + L I+ + +K ++
Sbjct: 1543 IQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1575
Score = 67.0 bits (162), Expect = 2e-10
Identities = 110/540 (20%), Positives = 223/540 (41%), Gaps = 89/540 (16%)
Query: 929 QLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESL 988
+LQR + + N E + T E+E KK+L RLQE E
Sbjct: 1359 ELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQ-----------RLQEAEE-- 1405
Query: 989 RTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLK--DEKEQLNNQILCQSKDEF 1046
++ +++ LE R ++E+ + D+E+ NA D+K++ +++L + K ++
Sbjct: 1406 --HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKY 1463
Query: 1047 AQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSS 1106
+ ELE + ++L E +++ Y+ D++ ++ R N + Q
Sbjct: 1464 EETQA-------ELEASQKESRSLSTELFKVKNVYEESLDQLETLR-----RENKNLQQE 1511
Query: 1107 LESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKL--- 1163
+ + + +I + E +QVE+ E A L++ LE E K+
Sbjct: 1512 ISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAA-------LEEAEASLEHEEGKILRI 1564
Query: 1164 QVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQ---ELESEN------KKLKN 1214
Q++L + + + +K+ + + D L N +++ E+ S N KK++
Sbjct: 1565 QLELNQVKSEVDRKIAEKDEEID-QLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEG 1623
Query: 1215 DLNELR-------KAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLIL--R 1265
DLNE+ + A+ ++ G L L+ E+L KE++ I+ R
Sbjct: 1624 DLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDL---KEQLAIVERR 1680
Query: 1266 TQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYH----GVCQTNSKTEDWG 1321
++ A+ L + RS ++ +D + ++ H + T K E
Sbjct: 1681 ANLLQAEIEELWATLEQTE---RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE--- 1734
Query: 1322 YLNEDGELGLAYQGLKQVAR---------LLEAQLQAQSLEHEEE----VEHLKAQLEAL 1368
N+ +L + + Q +R + +A + A+ L+ E++ +E +K LE
Sbjct: 1735 --NDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT 1792
Query: 1369 KEEMDKQQQTFCQTLLLSPEAQV---EFGVQQEISRLTNENLDLKELVEKLEKNERKLKK 1425
+++ + Q L + Q+ E V++ + NE E V+ L K+ER++K+
Sbjct: 1793 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKE 1852
Score = 62.4 bits (150), Expect = 4e-09
Identities = 124/662 (18%), Positives = 278/662 (41%), Gaps = 70/662 (10%)
Query: 851 VRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML-KARRELKALRIE 909
+RR + ++H+A + ++H + + I R+ K +E L++E
Sbjct: 1177 LRRDLEEATLQHEAMVAA------LRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKME 1230
Query: 910 ----ARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKE 965
+ +AE + + +E ++ R +++Q E KT E+ + T + RL+ E
Sbjct: 1231 TDDLSSNAEAISKAKGNLE----KMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTE 1286
Query: 966 LVHYQQSPGEDTSLRLQ---------EEVESLRTELQRAHSERKILEDAHSREK---DEL 1013
Y + E +L Q +++E L+ +L+ + L A + D L
Sbjct: 1287 AGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLL 1346
Query: 1014 RKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKE 1073
R++ + ++ A L+ + N+++ Q + ++ ++++ +ELEE + + L +
Sbjct: 1347 REQYEEEQEGKAELQRALSKANSEV-AQWRTKYETDAIQRT---EELEEAKKK---LAQR 1399
Query: 1074 YSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEE 1133
+ E+ + + + +++T +N L+ + + + + + + + +V
Sbjct: 1400 LQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERS--NAACAALDKKQRNFDKVLS 1457
Query: 1134 IGLEKAAMDMTVFLKLQKRVRELEQERKKLQ-VQLEKREQQDSKKVQAEPPQTDIDLDPN 1192
+K QK R L E K++ V E +Q ++ + + + Q +I D
Sbjct: 1458 EWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEIS-DLT 1516
Query: 1193 ADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL-AH 1251
+A + ELE K+++ + E++ A+ + G L LNQ+K
Sbjct: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1576
Query: 1252 EELEVRKEEVLILR---TQIVSADQRRLAGRNAEPNINARSSWPNSEKHVD---QEDAIE 1305
++ + EE+ L+ T++V Q L + I +R+ +K ++ E I+
Sbjct: 1577 RKIAEKDEEIDQLKRNHTRVVETMQSTL-----DAEIRSRNDALRVKKKMEGDLNEMEIQ 1631
Query: 1306 AYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQL 1365
H + Y N G LK+ L+ L+ Q + +E++ ++ +
Sbjct: 1632 LNHANRLAAESLRN--YRNTQGI-------LKETQLHLDDALRGQE-DLKEQLAIVERRA 1681
Query: 1366 EALKEEMDKQQQTFCQTLLLSPEAQVE-FGVQQEISRLTNENLDLKELVEKLEKNERKLK 1424
L+ E+++ T QT A+ E + + L +N L +KLE + +L+
Sbjct: 1682 NLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQ 1741
Query: 1425 KQLKIYMKKAQDLE--AAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIR 1482
+++ ++++++ E A +A+ + EL +KE+D LE K++ ++
Sbjct: 1742 SEVEEVIQESRNAEEKAKKAITDAAMMAEEL-------KKEQDTSAHLERMKKNLEQTVK 1794
Query: 1483 NL 1484
+L
Sbjct: 1795 DL 1796
Score = 44.3 bits (103), Expect = 0.001
Identities = 71/327 (21%), Positives = 123/327 (37%), Gaps = 69/327 (21%)
Query: 859 LMEHKATTIQKHVRG-WMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLK 917
++E +A +Q + W +R R A +L A ++ L + S + K
Sbjct: 1676 IVERRANLLQAEIEELWATLEQTERSRKIA-----EQELLDASERVQLLHTQNTSLINTK 1730
Query: 918 RLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDT 977
+ +EN V QLQ +++E +E + E+ + M E LKKE +DT
Sbjct: 1731 KK---LENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKE---------QDT 1778
Query: 978 SLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQ 1037
S L+ R K L + V DL+ DE EQL
Sbjct: 1779 SAHLE-------------------------RMKKNLEQTVKDLQHR----LDEAEQL--- 1806
Query: 1038 ILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGH 1097
L K + + + ++ E+E E+ R VK + E+R L QT
Sbjct: 1807 ALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKEL------TYQTEED 1860
Query: 1098 RRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELE 1157
R+N L ++ + ++ E E++ +++ F KLQ + E E
Sbjct: 1861 RKNVLRLQDL----------VDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAE 1910
Query: 1158 QERKKLQVQLEK---REQQDSKKVQAE 1181
+ + Q+ K + ++ K+ AE
Sbjct: 1911 ERADIAESQVNKLRVKSREVHTKISAE 1937
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 570 bits (1468), Expect = e-162
Identities = 463/1607 (28%), Positives = 773/1607 (48%), Gaps = 191/1607 (11%)
Query: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
T V++ DP E + A T +EG K + +T + V+ +Q+ F NP
Sbjct: 36 TSVFVVDPKESFVKA--TVQSREGGK-----VTAKTEAGATVTVKDDQV-FPMNPPKYDK 87
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ +++LHEPAVL+NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 88 IEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGK 146
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+ + +
Sbjct: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 206
Query: 191 N-----------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANM 239
+E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++
Sbjct: 207 KEEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
Query: 240 RTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIE 297
TYLLEKSRV FQ ER+YHIFYQ+ + P+ E+ L T+ D+ + SQG + ++
Sbjct: 267 ETYLLEKSRVTFQLKAERSYHIFYQIMSNKK-PDLIEMLLITTNPYDYAFVSQG-EITVP 324
Query: 298 GVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCS 350
+DD E+ T A +LG ++SI+K+ +++H G++ QAE DG
Sbjct: 325 SIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE-- 382
Query: 351 ISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYA 410
++ + YL N + + + LC+ ++ +E K ++QQV NA ALAK +Y
Sbjct: 383 VADKAAYLQN------LNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYD 436
Query: 411 QLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHV 470
++F W+V IN+ L T + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+
Sbjct: 437 KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHM 496
Query: 471 FKLEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLY 529
F LEQEEY KE I WT IDF D CI+LIE +GI +L+EEC PK TD ++ KLY
Sbjct: 497 FVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLY 556
Query: 530 DRH-SSSQHFQKPRMS----NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASK 584
++H S +FQKP+ + F ++H+A V+Y G+L+KN+D + E + + + S
Sbjct: 557 EQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSA 616
Query: 585 FPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLM 644
+A LF GK K +TV FR +L+ LM
Sbjct: 617 MKTLALLFVGATGAEAEAGGGKKGGKK-------------KGSSFQTVSALFRENLNKLM 663
Query: 645 ETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFF 704
L +T PH+VRCI PN+ K P + + + QLR GVLE IRI G+PSR Y DF
Sbjct: 664 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 723
Query: 705 NRYRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRAD 762
RY+VL E D K +L ++ D +++FG TK+FF+AG + LE++R +
Sbjct: 724 QRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDE 783
Query: 763 KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822
K Q RG+L +V+Y ++ ++ +C + R ++ ++ +
Sbjct: 784 KLAQLITRTQAMCRGFLARVEYQKMVERRESI--FCIQYNVRA----FMNVKHWPWMKLY 837
Query: 823 YRMQRARQAYQRVRRAAVVIQAF--TRAMFVRRTYRQVLMEHKATTI--QKHVRGWMARR 878
++++ ++ + + A + + F T+ + ++ +E K T+ +K+ +
Sbjct: 838 FKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQA 897
Query: 879 HFQRLRDAAIVIQCAFRMLKARRELKA-LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ 937
L DA + +++K + +L+A ++ AE + +N + K +RK++++
Sbjct: 898 EADSLADAE---ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK----KRKLEDE 950
Query: 938 NKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHS 997
E K + L +T + V ++ E+ L EE+ L + +
Sbjct: 951 CSELKKDIDDLELTLAK------------VEKEKHATENKVKNLTEEMAGLDETIAKLTK 998
Query: 998 ERKILEDAHSREKDELR-----------------KRVAD----LEQENAL---LKDEKEQ 1033
E+K L++AH + D+L+ ++V D LEQE + L+ K +
Sbjct: 999 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRK 1058
Query: 1034 LNNQI-LCQSKDEFAQN---SVKENLMKKE---------LEEERSRYQNLVKEYSQLEQR 1080
L + L Q +N + E L KKE +E+E++ L K+ +L+ R
Sbjct: 1059 LEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQAR 1118
Query: 1081 YDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA------------- 1127
+ L +E I + + +S L + S E G A
Sbjct: 1119 IEELEEE--IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176
Query: 1128 --LQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQ-----A 1180
+ +EE L+ A T+ K V EL ++ LQ +K E++ S+ A
Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1236
Query: 1181 EPPQTDIDLDPNADLAYNSLKRQ--ELESENKKLKNDLNELRKAVADQATQNNSSHGSPD 1238
+T N + +L+ Q E++++ ++ + +N+L A T++ D
Sbjct: 1237 SNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLD 1296
Query: 1239 SYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHV 1298
L++QL + + EE L+ Q+ + + A +A + +
Sbjct: 1297 EKDTLVSQLSRGKQAFTQQIEE---LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE 1353
Query: 1299 DQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEV 1358
+QE E + + NS+ W E + + L++ + L +LQ + EH E V
Sbjct: 1354 EQEAKAELQRAMSKANSEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQ-DAEEHVEAV 1411
Query: 1359 EHLKAQLEALKEE---------------------MDKQQQTFCQTLL----LSPEAQVEF 1393
A LE K+ +DK+Q+ F + L E E
Sbjct: 1412 NAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAEL 1471
Query: 1394 GVQQEISR-LTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHE 1452
Q+ SR L+ E +K E+ LK++ K ++ DL + +A+ ++ HE
Sbjct: 1472 EASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDL--TEQIAEGGKRIHE 1529
Query: 1453 LNR-QVTVQRKEKDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492
L + + V++++ + Q LE H+E + L I+ + +K ++
Sbjct: 1530 LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1576
Score = 63.5 bits (153), Expect = 2e-09
Identities = 124/662 (18%), Positives = 268/662 (40%), Gaps = 69/662 (10%)
Query: 851 VRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML-KARRELKALRIE 909
+RR + ++H+AT + ++H + + I R+ K +E +++E
Sbjct: 1178 MRRDLEEATLQHEATAAT------LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1231
Query: 910 ARS-AEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVH 968
A +++ ++ N + ++ R +++Q E KT E+ + T + RL+ E
Sbjct: 1232 IDDLASNMETVSKAKGN-LEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGE 1290
Query: 969 YQQSPGEDTSLRLQ---------EEVESLRTELQRAHSERKILEDAHSREK---DELRKR 1016
Y + E +L Q +++E L+ +L+ + L A + D LR++
Sbjct: 1291 YSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQ 1350
Query: 1017 VADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQ 1076
+ ++ A L+ + N+++ Q + ++ ++++ +ELEE + + L +
Sbjct: 1351 YEEEQEAKAELQRAMSKANSEV-AQWRTKYETDAIQRT---EELEEAKKK---LAQRLQD 1403
Query: 1077 LEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGL 1136
E+ + + + +++T +N L D + + + + + ++
Sbjct: 1404 AEEHVEAVNAKCASLEKTKQRLQN--EVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1461
Query: 1137 EKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKR-EQQDSKKVQAEPPQTDIDLDPNADL 1195
+K QK R L E K++ E+ +Q ++ K + + Q +I D +
Sbjct: 1462 QKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEIS-DLTEQI 1520
Query: 1196 AYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL------ 1249
A + ELE K+++ + +EL+ A+ + G L LNQ+K
Sbjct: 1521 AEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1580
Query: 1250 --AHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVD----QEDA 1303
EE++ K + + + S + RN + + +E + A
Sbjct: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640
Query: 1304 IEAYHGVCQTNSKTEDW-----GYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEV 1358
EA T + +D L +L +++ A LL+A+++ E+
Sbjct: 1641 AEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1700
Query: 1359 EHLKAQLEALKEEMDKQQQTFCQ-TLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLE 1417
K + L + ++ Q Q T L++ + ++E +IS++ E +++++++
Sbjct: 1701 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLE----TDISQIQGE---MEDIIQEAR 1753
Query: 1418 KNERKLKKQLKIYMKKAQDLEAAQ-ALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKED 1476
E K KK + A++L+ Q A ER + L + V KD Q H+ D
Sbjct: 1754 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV------KDLQ-----HRLD 1802
Query: 1477 EA 1478
EA
Sbjct: 1803 EA 1804
Score = 45.8 bits (107), Expect = 4e-04
Identities = 70/343 (20%), Positives = 142/343 (41%), Gaps = 48/343 (13%)
Query: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTL------SEQLSVTTSTYTMEV 959
L E RS RL ME + +++ +++ N+ ++ + T + +
Sbjct: 1605 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDA 1664
Query: 960 ERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVAD 1019
R +++L Q + E + LQ E+E LR L++ RKI E +E + +RV
Sbjct: 1665 LRSQEDLKE-QLAMVERRANLLQAEIEELRATLEQTERSRKIAE----QELLDASERVQL 1719
Query: 1020 LEQENALLKDEKEQLN---NQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEY-- 1074
L +N L + K++L +QI + +D + E KK + + + L KE
Sbjct: 1720 LHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDT 1779
Query: 1075 -SQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEE 1133
+ LE+ NL + ++ HR + + Q +L+ + + + E ++ ++
Sbjct: 1780 SAHLERMKKNLEQTVKDLQ----HRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1835
Query: 1134 IGLE-----------------KAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDS- 1175
+E + D L+LQ V +L+ + K + Q E+ E+Q +
Sbjct: 1836 RNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNV 1895
Query: 1176 -----KKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLK 1213
+++Q E + + AD+A + + + ++S K
Sbjct: 1896 NLSKFRRIQHELEEA----EERADIAESQVNKLRVKSREVHTK 1934
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 569 bits (1466), Expect = e-161
Identities = 457/1595 (28%), Positives = 777/1595 (48%), Gaps = 167/1595 (10%)
Query: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
T V++ DP E + A + +EG K + +T + V+ +Q+ F NP
Sbjct: 36 TSVFVVDPKESYVKAIVQS--REGGK-----VTAKTEAGATVTVKEDQV-FSMNPPKYDK 87
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ +++LHEPAVL+NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 88 IEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGK 146
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+ + +
Sbjct: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 206
Query: 191 N-----------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANM 239
+E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++
Sbjct: 207 KEEPASGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADI 266
Query: 240 RTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIE 297
TYLLEKSRV FQ ER+YHIFYQ+ + PE E+ L T+ DF + SQG + ++
Sbjct: 267 ETYLLEKSRVTFQLKAERSYHIFYQILSNKK-PELIEMLLITTNPYDFAFVSQG-EITVP 324
Query: 298 GVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCS 350
+DD E+ T A +LG +++I+K+ +++H G++ QAE DG
Sbjct: 325 SIDDQEELMATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTE-- 382
Query: 351 ISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYA 410
++ + YL++ + + + LC+ ++ +E K ++QQV NA ALAK IY
Sbjct: 383 VADKAAYLTS------LNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYE 436
Query: 411 QLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHV 470
++F W+V IN+ L T + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+
Sbjct: 437 KMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHM 496
Query: 471 FKLEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLY 529
F LEQEEY KE I W IDF D CI+LIE +GI +L+EEC PK TD ++ KLY
Sbjct: 497 FVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLY 556
Query: 530 DRH-SSSQHFQKPRMS----NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASK 584
++H S +FQKP+ + F +VH+A V+Y G+L+KN+D + E + + + S
Sbjct: 557 EQHLGKSNNFQKPKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSA 616
Query: 585 FPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLM 644
+A LF + GK K +TV FR +L+ LM
Sbjct: 617 MKTLAFLFSGAQTAEAEGGGGKKGGKK-------------KGSSFQTVSALFRENLNKLM 663
Query: 645 ETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFF 704
L +T PH+VRCI PN+ K P + + + QLR GVLE IRI G+PSR Y DF
Sbjct: 664 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 723
Query: 705 NRYRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRAD 762
RY+VL E D K +L ++ D +++FG TK+FF+AG + LE++R +
Sbjct: 724 QRYKVLNASAIPEGQFIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDE 783
Query: 763 KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822
K Q RG+L +V++ ++ ++ +C + R ++ ++ +
Sbjct: 784 KLAQLITRTQAICRGFLMRVEFRKMMERRESI--FCIQYNIRA----FMNVKHWPWMKLY 837
Query: 823 YRMQRARQAYQRVRRAAVVIQAF--TRAMFVRRTYRQVLMEHKATTI--QKHVRGWMARR 878
++++ ++ + + A + + F T+ + ++ +E K T+ +K+ +
Sbjct: 838 FKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQA 897
Query: 879 HFQRLRDAAIVIQCAFRMLKARRELKA-LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ 937
L DA + +++K + +L+A ++ AE + +N + K +RK++++
Sbjct: 898 EADALADAE---ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK----KRKLEDE 950
Query: 938 NKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPG--EDTSLRLQEEVESLRTELQRA 995
E K + L +T + E + ++ + + ++T +L +E ++L+ Q+
Sbjct: 951 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQT 1010
Query: 996 HSERKILED---AHSREKDELRKRVAD----LEQENALLKD---EKEQLNNQI-LCQSKD 1044
+ ++ ED ++ K +L ++V D LEQE L D K +L + L Q
Sbjct: 1011 LDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQEST 1070
Query: 1045 EFAQN---SVKENLMKKE---------LEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIK 1092
+N + E L KKE +E+E++ L K+ +L+ R + L +E I
Sbjct: 1071 MDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEE--IEA 1128
Query: 1093 QTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA---------------LQQVEEIGLE 1137
+ + +S L + S E G A + +EE L+
Sbjct: 1129 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQ 1188
Query: 1138 KAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAEPPQTDIDLDPNADLA 1196
A + K V EL ++ LQ +K E++ S+ K++ ++++ A
Sbjct: 1189 HEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKAN 1248
Query: 1197 YNSLKR------QELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLA 1250
+ + R E++++ ++ + +NEL A T++ D +++QL
Sbjct: 1249 FEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRG 1308
Query: 1251 HEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGV 1310
+ + EE L+ Q+ + + +A + + +QE E G+
Sbjct: 1309 KQAFTQQIEE---LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGM 1365
Query: 1311 CQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKE 1370
+ NS+ W E + + L++ + L +LQ + EH E V A LE K+
Sbjct: 1366 SKANSEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQ-DAEEHVEAVNSKCASLEKTKQ 1423
Query: 1371 E---------------------MDKQQQTFCQTLL----LSPEAQVEFGVQQEISR-LTN 1404
+DK+Q+ F + L E Q E Q+ SR L+
Sbjct: 1424 RLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLST 1483
Query: 1405 ENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNR-QVTVQRKE 1463
E +K E+ + LK++ K ++ DL + +A+ + HEL + + + ++
Sbjct: 1484 ELFKVKNAYEESLDHLETLKRENKNLQQEISDL--TEQIAEGGKHIHELEKVKKQLDHEK 1541
Query: 1464 KDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492
+ Q LE H+E + L I+ + +K ++
Sbjct: 1542 SELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI 1576
Score = 62.8 bits (151), Expect = 3e-09
Identities = 126/669 (18%), Positives = 265/669 (39%), Gaps = 84/669 (12%)
Query: 851 VRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML-KARRELKALRIE 909
+RR + ++H+AT + ++H + + I R+ K +E L++E
Sbjct: 1178 MRRDLEESTLQHEATAAA------LRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKME 1231
Query: 910 ARS-AEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVH 968
A +++ ++ N ++ R +++Q E KT E+ + + + RL E
Sbjct: 1232 INDLASNMETVSKAKAN-FEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGE 1290
Query: 969 YQQSPGEDTSLRLQ---------EEVESLRTELQRAHSERKILEDAHSREK---DELRKR 1016
+ + E ++ Q +++E L+ +L+ + L A + D LR++
Sbjct: 1291 FSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQ 1350
Query: 1017 VADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQ 1076
+ ++ A L+ + N+++ Q + ++ ++++ +ELEE + + L +
Sbjct: 1351 YEEEQEAKAELQRGMSKANSEV-AQWRTKYETDAIQRT---EELEEAKKK---LAQRLQD 1403
Query: 1077 LEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESD-SNYPSISTSEIGDTEDAL-----QQ 1130
E+ + + + +++T +N ++ + SN I+ + D + Q+
Sbjct: 1404 AEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQK 1463
Query: 1131 VEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKR-EQQDSKKVQAEPPQTDIDL 1189
EE E A QK R L E K++ E+ + ++ K + + Q +I
Sbjct: 1464 YEETQAELEAS--------QKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEIS- 1514
Query: 1190 DPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL 1249
D +A ELE K+L ++ +EL+ ++ + G L LNQ+K
Sbjct: 1515 DLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKS 1574
Query: 1250 --------AHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVD-- 1299
EEL+ K L + + S + RN I + +E +
Sbjct: 1575 EIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLN 1634
Query: 1300 --QEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEE 1357
A EA + T +D +D G LK+ ++E + + E
Sbjct: 1635 HANRQAAEALRNLRNTQGILKDTQLHLDDAIRG--QDDLKEQLAMVERRANLM----QAE 1688
Query: 1358 VEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLE 1417
VE L+A LE + +Q + + L +N L +KLE
Sbjct: 1689 VEELRASLERTERGRKMAEQEL-------------LDASERVQLLHTQNTSLINTKKKLE 1735
Query: 1418 KNERKLKKQLKIYMKKAQDLE--AAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKE 1475
+ +++ +++ +++A++ E A +A+ + EL +KE+D LE K+
Sbjct: 1736 TDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL-------KKEQDTSAHLERMKK 1788
Query: 1476 DEALLIRNL 1484
+ +++L
Sbjct: 1789 NMEQTVKDL 1797
Score = 48.5 bits (114), Expect = 6e-05
Identities = 94/451 (20%), Positives = 169/451 (37%), Gaps = 120/451 (26%)
Query: 914 EHLKRLNVGMENKVVQLQRKIDEQNK---EFKTLSEQLSVTTSTYTMEVERLKKELVHYQ 970
E LKR N ++ ++ L +I E K E + + +QL S +E + L H
Sbjct: 1500 ETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHE- 1558
Query: 971 QSPGEDTSLRLQEEVESLRTELQRAHSER------------KILEDAHSREKDELRKR-- 1016
E LR+Q E+ +++E+ R +E+ +++E S E+R R
Sbjct: 1559 ----EGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRND 1614
Query: 1017 -----------------------------VADLEQENALLKDEKEQLNNQILCQS--KDE 1045
+ +L +LKD + L++ I Q K++
Sbjct: 1615 ALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQ 1674
Query: 1046 FAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPS--- 1102
A + NLM+ E+EE R+ + + EQ + + + ++ H +N S
Sbjct: 1675 LAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLL-----HTQNTSLIN 1729
Query: 1103 NQSSLESDSNYPSISTSEIGDTE------------DALQQVEEIGLE----------KAA 1140
+ LE+D + +I DA EE+ E K
Sbjct: 1730 TKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1789
Query: 1141 MDMTV---------------------FLKLQKRVRELEQE---RKKLQVQLEKREQQDSK 1176
M+ TV KL+ RVRELE E +K V+ K ++ +
Sbjct: 1790 MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHER 1849
Query: 1177 KVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGS 1236
+V+ QT+ D N L+ Q+L KL+ + ++ + Q+N +
Sbjct: 1850 RVKELTYQTEED-------RKNILRLQDLVD---KLQTKVKAYKRQAEEAEEQSNVNLA- 1898
Query: 1237 PDSYSLLLNQLKLAHEELEVRKEEVLILRTQ 1267
+ L ++L+ A E ++ + +V LR +
Sbjct: 1899 --KFRKLQHELEEAKERADIAESQVNKLRVK 1927
Score = 45.4 bits (106), Expect = 5e-04
Identities = 65/275 (23%), Positives = 122/275 (44%), Gaps = 26/275 (9%)
Query: 1350 QSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQ-----TLLLSPEAQVEFGVQQEISRLTN 1404
+S E E+E+ ++K + E KEE+ K + + L+ + ++ VQ E L
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALA- 903
Query: 1405 ENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEK 1464
D +E ++L K + +L+ ++K ++A+D E A + K+ +L + + +K+
Sbjct: 904 ---DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINA--ELTAKKRKLEDECSELKKDI 958
Query: 1465 DFQGMLEYHKEDEALLIRNLVTDLKPQM--LSGTVPCLPAYILYMCIRHADYTNDDLKVH 1522
D + E E N V +L +M L T+ L + H T DDL++
Sbjct: 959 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ-TLDDLQME 1017
Query: 1523 SLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCR-LLHCLKQYSGD-----EGFM-TQNTA 1575
+T+ K L++ DD E + C L ++ GD E M T+N
Sbjct: 1018 EDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDK 1077
Query: 1576 KQNEHCL--KNFDLTEYRQVLSD---LSIQIYQQL 1605
+Q L K F+++ + + D L+IQ+ +++
Sbjct: 1078 QQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKI 1112
Score = 38.1 bits (87), Expect = 0.080
Identities = 36/150 (24%), Positives = 61/150 (40%), Gaps = 20/150 (13%)
Query: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQN----KEFKTLSEQLSVTTSTYTMEVER 961
L+ E ++ HL+R+ ME V LQ ++DE K K ++L EVE
Sbjct: 1773 LKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVES 1832
Query: 962 LKKELVH----------------YQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDA 1005
+K V YQ LRLQ+ V+ L+T+++ + + E+
Sbjct: 1833 EQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQ 1892
Query: 1006 HSREKDELRKRVADLEQENALLKDEKEQLN 1035
+ + RK +LE+ + Q+N
Sbjct: 1893 SNVNLAKFRKLQHELEEAKERADIAESQVN 1922
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 566 bits (1459), Expect = e-161
Identities = 363/957 (37%), Positives = 526/957 (54%), Gaps = 62/957 (6%)
Query: 19 DEVWRSAELTKDYKEGDKSL-------QLRLEDETILEYPIDVQRNQLPFLRNPDILVGE 71
D VW L +++ ++ Q+++ D+ E+ I Q +P + G
Sbjct: 8 DHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGV 67
Query: 72 NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQN 131
D+ L L+E +L NL +R+ + + IYTY G +LVA+NPY+ L IY + I Y+ +
Sbjct: 68 EDMIRLGDLNEAGILRNLLIRYRD-HLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126
Query: 132 MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191
+G+M PHIFA+A+ Y M R+ ++Q I+SGESGAGKT S K +++ A + G S
Sbjct: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW-- 184
Query: 192 IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVF 251
IE++VL ++PI+EA GNAKT RNDNSSRFGKYI I F+KR I GA + YLLEKSRV
Sbjct: 185 IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244
Query: 252 QADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQA 311
QA DERNYH+FY + + K+L L A D+ Y + G + EG D++++ R A
Sbjct: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304
Query: 312 FTLLGVKESHQMSIFKIIASILHLGSVAIQAE--RDGDSCSI--SPQDVYLSNFCRLLGV 367
+L ++ I K++A+ILHLG++ +A + D+C + SP L+ LL V
Sbjct: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPS---LATAASLLEV 361
Query: 368 EHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTS 427
+ L R L+T ET +S +Q ++ R+A K IY +LF WIV+ IN A++
Sbjct: 362 NPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKP 421
Query: 428 LKQ-----HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQ 482
Q IG+LDI+GFE F VNSFEQ CIN+ANE LQQ F HVFKLEQEEY E
Sbjct: 422 PSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLES 481
Query: 483 IPWTLIDFYDNQPCIDLIEAK-LGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKP 541
I W I+F DNQ +D+I K + I+ L+DEE K PKGTD KL +H + ++ P
Sbjct: 482 IDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPP 541
Query: 542 RMSN-TAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVP 600
+ ++ T F I HFA V Y + GFLEKNRDT++ + I ++ +S+ + +F D
Sbjct: 542 KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD----- 596
Query: 601 ATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP 660
M ++ T+ QF+ SL LLM TL A P +VRCIKP
Sbjct: 597 ------------------VAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKP 638
Query: 661 NDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVK--KRELAN 718
N+ K P FD V+QLR G++ETIRI AGYP R+++ +F RYRVL+ K
Sbjct: 639 NEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQ 698
Query: 719 TDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGW 778
D + C+ + E ++ D +Q G+TKIF + LE R I++QK +RG+
Sbjct: 699 GDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGF 758
Query: 779 LQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRA 838
+ + +LK A +QR+ RGH R+ +R + LQ +R ++ Q Y+ R+
Sbjct: 759 KDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR--LGFLRLQALHRSRKLHQQYRLARQR 816
Query: 839 AVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML- 897
+ QA RA VR+ +R L T+Q + RG +ARR QRLR + A +M
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLW--AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL 874
Query: 898 ----KARRELKALRI-EARSAEHLKRL-NVGMENKVVQLQRKIDEQNKEFKTLSEQL 948
K R+E+ A + E +H +RL + E+ +L+ K E + K L EQ+
Sbjct: 875 AEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEK--EAARRKKELLEQM 929
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 566 bits (1459), Expect = e-161
Identities = 363/957 (37%), Positives = 526/957 (54%), Gaps = 62/957 (6%)
Query: 19 DEVWRSAELTKDYKEGDKSL-------QLRLEDETILEYPIDVQRNQLPFLRNPDILVGE 71
D VW L +++ ++ Q+++ D+ E+ I Q +P + G
Sbjct: 8 DHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGV 67
Query: 72 NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQN 131
D+ L L+E +L NL +R+ + + IYTY G +LVA+NPY+ L IY + I Y+ +
Sbjct: 68 EDMIRLGDLNEAGILRNLLIRYRD-HLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126
Query: 132 MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191
+G+M PHIFA+A+ Y M R+ ++Q I+SGESGAGKT S K +++ A + G S
Sbjct: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW-- 184
Query: 192 IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVF 251
IE++VL ++PI+EA GNAKT RNDNSSRFGKYI I F+KR I GA + YLLEKSRV
Sbjct: 185 IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244
Query: 252 QADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQA 311
QA DERNYH+FY + + K+L L A D+ Y + G + EG D++++ R A
Sbjct: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304
Query: 312 FTLLGVKESHQMSIFKIIASILHLGSVAIQAE--RDGDSCSI--SPQDVYLSNFCRLLGV 367
+L ++ I K++A+ILHLG++ +A + D+C + SP L+ LL V
Sbjct: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPS---LATAASLLEV 361
Query: 368 EHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTS 427
+ L R L+T ET +S +Q ++ R+A K IY +LF WIV+ IN A++
Sbjct: 362 NPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKP 421
Query: 428 LKQ-----HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQ 482
Q IG+LDI+GFE F VNSFEQ CIN+ANE LQQ F HVFKLEQEEY E
Sbjct: 422 PSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLES 481
Query: 483 IPWTLIDFYDNQPCIDLIEAK-LGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKP 541
I W I+F DNQ +D+I K + I+ L+DEE K PKGTD KL +H + ++ P
Sbjct: 482 IDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPP 541
Query: 542 RMSN-TAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVP 600
+ ++ T F I HFA V Y + GFLEKNRDT++ + I ++ +S+ + +F D
Sbjct: 542 KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD----- 596
Query: 601 ATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP 660
M ++ T+ QF+ SL LLM TL A P +VRCIKP
Sbjct: 597 ------------------VAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKP 638
Query: 661 NDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVK--KRELAN 718
N+ K P FD V+QLR G++ETIRI AGYP R+++ +F RYRVL+ K
Sbjct: 639 NEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQ 698
Query: 719 TDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGW 778
D + C+ + E ++ D +Q G+TKIF + LE R I++QK +RG+
Sbjct: 699 GDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGF 758
Query: 779 LQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRA 838
+ + +LK A +QR+ RGH R+ +R + LQ +R ++ Q Y+ R+
Sbjct: 759 KDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR--LGFLRLQALHRSRKLHQQYRLARQR 816
Query: 839 AVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML- 897
+ QA RA VR+ +R L T+Q + RG +ARR QRLR + A +M
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLW--AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL 874
Query: 898 ----KARRELKALRI-EARSAEHLKRL-NVGMENKVVQLQRKIDEQNKEFKTLSEQL 948
K R+E+ A + E +H +RL + E+ +L+ K E + K L EQ+
Sbjct: 875 AEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEK--EAARRKKELLEQM 929
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 566 bits (1459), Expect = e-161
Identities = 363/957 (37%), Positives = 526/957 (54%), Gaps = 62/957 (6%)
Query: 19 DEVWRSAELTKDYKEGDKSL-------QLRLEDETILEYPIDVQRNQLPFLRNPDILVGE 71
D VW L +++ ++ Q+++ D+ E+ I Q +P + G
Sbjct: 8 DHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGV 67
Query: 72 NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQN 131
D+ L L+E +L NL +R+ + + IYTY G +LVA+NPY+ L IY + I Y+ +
Sbjct: 68 EDMIRLGDLNEAGILRNLLIRYRD-HLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKK 126
Query: 132 MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191
+G+M PHIFA+A+ Y M R+ ++Q I+SGESGAGKT S K +++ A + G S
Sbjct: 127 IGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW-- 184
Query: 192 IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVF 251
IE++VL ++PI+EA GNAKT RNDNSSRFGKYI I F+KR I GA + YLLEKSRV
Sbjct: 185 IEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCR 244
Query: 252 QADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQA 311
QA DERNYH+FY + + K+L L A D+ Y + G + EG D++++ R A
Sbjct: 245 QALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSA 304
Query: 312 FTLLGVKESHQMSIFKIIASILHLGSVAIQAE--RDGDSCSI--SPQDVYLSNFCRLLGV 367
+L ++ I K++A+ILHLG++ +A + D+C + SP L+ LL V
Sbjct: 305 MKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPS---LATAASLLEV 361
Query: 368 EHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTS 427
+ L R L+T ET +S +Q ++ R+A K IY +LF WIV+ IN A++
Sbjct: 362 NPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKP 421
Query: 428 LKQ-----HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQ 482
Q IG+LDI+GFE F VNSFEQ CIN+ANE LQQ F HVFKLEQEEY E
Sbjct: 422 PSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLES 481
Query: 483 IPWTLIDFYDNQPCIDLIEAK-LGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKP 541
I W I+F DNQ +D+I K + I+ L+DEE K PKGTD KL +H + ++ P
Sbjct: 482 IDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPP 541
Query: 542 RMSN-TAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVP 600
+ ++ T F I HFA V Y + GFLEKNRDT++ + I ++ +S+ + +F D
Sbjct: 542 KNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD----- 596
Query: 601 ATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP 660
M ++ T+ QF+ SL LLM TL A P +VRCIKP
Sbjct: 597 ------------------VAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKP 638
Query: 661 NDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVK--KRELAN 718
N+ K P FD V+QLR G++ETIRI AGYP R+++ +F RYRVL+ K
Sbjct: 639 NEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQ 698
Query: 719 TDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGW 778
D + C+ + E ++ D +Q G+TKIF + LE R I++QK +RG+
Sbjct: 699 GDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGF 758
Query: 779 LQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRA 838
+ + +LK A +QR+ RGH R+ +R + LQ +R ++ Q Y+ R+
Sbjct: 759 KDRSNFLKLKNAATLIQRHWRGHNCRKNYGLMR--LGFLRLQALHRSRKLHQQYRLARQR 816
Query: 839 AVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML- 897
+ QA RA VR+ +R L T+Q + RG +ARR QRLR + A +M
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLW--AVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL 874
Query: 898 ----KARRELKALRI-EARSAEHLKRL-NVGMENKVVQLQRKIDEQNKEFKTLSEQL 948
K R+E+ A + E +H +RL + E+ +L+ K E + K L EQ+
Sbjct: 875 AEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEK--EAARRKKELLEQM 929
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 564 bits (1454), Expect = e-160
Identities = 462/1608 (28%), Positives = 769/1608 (47%), Gaps = 191/1608 (11%)
Query: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
T V++ +P E + + +EG K + ++ E L V+ +Q+ F NP
Sbjct: 36 TSVFVAEPKESFVKGTIQS--REGGK-VTVKTEGGATLT----VKDDQV-FPMNPPKYDK 87
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ +++LHEPAVL+NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 88 IEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGK 146
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+ + +
Sbjct: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 206
Query: 191 N-----------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANM 239
+E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++
Sbjct: 207 KEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
Query: 240 RTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIE 297
TYLLEKSRVVFQ ER+YHIFYQ+ + PE E+ L T+ D+ + SQG + S+
Sbjct: 267 ETYLLEKSRVVFQLKAERSYHIFYQITSNKK-PELIEMLLITTNPYDYPFVSQG-EISVA 324
Query: 298 GVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCS 350
+DD E+ T A +LG ++SI+K+ +++H G++ QAE DG
Sbjct: 325 SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTE-- 382
Query: 351 ISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYA 410
++ + YL + + + + LC+ ++ +E K +++QV NA ALAK +Y
Sbjct: 383 VADKAAYLQS------LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYE 436
Query: 411 QLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHV 470
++F W+V IN+ L T + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+
Sbjct: 437 KMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHM 496
Query: 471 FKLEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLY 529
F LEQEEY KE I WT IDF D CI+LIE +GI +L+EEC PK TD ++ KLY
Sbjct: 497 FVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLY 556
Query: 530 DRH-SSSQHFQKPRM----SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASK 584
D+H S +FQKP++ + F ++H+A V+Y G+LEKN+D + E + + + S
Sbjct: 557 DQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSA 616
Query: 585 FPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLM 644
+A LF + T G+G+ A+ K + TV FR +L+ LM
Sbjct: 617 MKTLAQLFSGAQ-----TAEGEGAGG-----GAKKGGKKKGSSFQ-TVSALFRENLNKLM 665
Query: 645 ETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFF 704
L +T PH+VRCI PN+ K P + + + QLR GVLE IRI G+PSR Y DF
Sbjct: 666 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 725
Query: 705 NRYRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRAD 762
RY+VL E D K +L ++ D +++FG TK+FF+AG + LE++R D
Sbjct: 726 QRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDD 785
Query: 763 KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822
K +I +T Q CRG LAR + + R A+
Sbjct: 786 KLAQ---LITRT--------------------QARCRGFLARVEYQRMVERREAI----- 817
Query: 823 YRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQ---VLMEHKATTIQKHVRGWMARRH 879
+ +Q +++ V+ + F ++ + M+ + I+ + A+R
Sbjct: 818 FCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRK 877
Query: 880 FQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ-- 937
+ ++ + L+ + E + L + L + + +E K+ ++ + +++
Sbjct: 878 ELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEE 937
Query: 938 -NKEFKTLSEQLSVTTSTYTMEVERLKKEL--VHYQQSPGEDTSLRLQEEVESLRTELQR 994
N E +L S +++ L+ L V ++ E+ L EE+ L + +
Sbjct: 938 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 997
Query: 995 AHSERKILEDAHSREKDELR-----------------KRVAD----LEQENAL---LKDE 1030
E+K L++AH + D+L+ ++V D LEQE L L+
Sbjct: 998 LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERA 1057
Query: 1031 KEQLNNQILCQSKD----EFAQNSVKENLMKKE---------LEEERSRYQNLVKEYSQL 1077
K +L + + E + + E L KKE +E+E++ L K+ +L
Sbjct: 1058 KRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
Query: 1078 EQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA---------- 1127
+ R + L +E I + + +S L + S E G A
Sbjct: 1118 QARIEELEEE--IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175
Query: 1128 -----LQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAE 1181
+ +EE L+ A T+ K V EL ++ LQ +K E++ S+ K++ +
Sbjct: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235
Query: 1182 PPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYS 1241
++++ A + R LE + +LK+ E ++ + D Q +S
Sbjct: 1236 DLASNVETVSKAKGNLEKMCR-TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFS 1294
Query: 1242 LLLNQLKLAHEELEVRK----EEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKH 1297
L++ + +L K +++ L+ Q+ + + A +A + +
Sbjct: 1295 RQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYE 1354
Query: 1298 VDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEE 1357
+QE E + + N++ W E + + L++ + L +LQA EH E
Sbjct: 1355 EEQESKAELQRALSKANTEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQAAE-EHVEA 1412
Query: 1358 VEHLKAQLEALKEE---------------------MDKQQQTFCQTLL----LSPEAQVE 1392
V A LE K+ +DK+Q+ F + L E E
Sbjct: 1413 VNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE 1472
Query: 1393 FGVQQEISR-LTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRH 1451
Q+ +R L E +K E+ LK++ K ++ DL + +A+ ++ H
Sbjct: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL--TEQIAEGGKRIH 1530
Query: 1452 ELNR-QVTVQRKEKDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492
EL + + V++++ + Q LE H+E + L I+ + +K ++
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578
Score = 59.3 bits (142), Expect = 3e-08
Identities = 119/660 (18%), Positives = 282/660 (42%), Gaps = 66/660 (10%)
Query: 851 VRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML-KARRELKALRIE 909
+RR + ++H+AT + ++H + + I R+ K +E +++E
Sbjct: 1180 MRRDLEEATLQHEATAAT------LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1233
Query: 910 -----------ARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQ---LSVTTSTY 955
+++ +L+++ +E+++ +L+ K +EQ + L+ Q L + +
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEF 1293
Query: 956 TMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREK---DE 1012
+ +++ +KE + Q S G+ +++E L+ +L+ + L A + D
Sbjct: 1294 SRQLD--EKEALVSQLSRGKQA---FTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348
Query: 1013 LRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVK 1072
LR++ + ++ A L+ + N ++ Q + ++ ++++ +ELEE + + L +
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEV-AQWRTKYETDAIQRT---EELEEAKKK---LAQ 1401
Query: 1073 EYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVE 1132
E+ + + + +++T +N L+ + + + + + + ++
Sbjct: 1402 RLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT--NAACAALDKKQRNFDKIL 1459
Query: 1133 EIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKR-EQQDSKKVQAEPPQTDIDLDP 1191
+K QK R L E K++ E+ +Q ++ K + + Q +I D
Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS-DL 1518
Query: 1192 NADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL-A 1250
+A + ELE K+++ + EL+ A+ + G L LNQ+K
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578
Query: 1251 HEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVD---QEDAIEAY 1307
++ + EE+ L+ + + + +AE I +R+ +K ++ E I+
Sbjct: 1579 DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAE--IRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Query: 1308 HGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEA 1367
H + Y N G LK L+ L++Q + +E++ ++ +
Sbjct: 1637 HANRMAAEALRN--YRNTQGI-------LKDTQIHLDDALRSQE-DLKEQLAMVERRANL 1686
Query: 1368 LKEEMDKQQQTFCQTLLLSPEAQVE-FGVQQEISRLTNENLDLKELVEKLEKNERKLKKQ 1426
L+ E+++ + T QT A+ E + + L +N L +KLE + +++ +
Sbjct: 1687 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGE 1746
Query: 1427 LKIYMKKAQDLE--AAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNL 1484
++ +++A++ E A +A+ + EL +KE+D LE K++ +++L
Sbjct: 1747 MEDILQEARNAEEKAKKAITDAAMMAEEL-------KKEQDTSAHLERMKKNMEQTVKDL 1799
Score = 47.8 bits (112), Expect = 1e-04
Identities = 78/371 (21%), Positives = 148/371 (39%), Gaps = 57/371 (15%)
Query: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVT------TSTYTMEV 959
L E RS RL ME + +++ +++ N+ T T + +
Sbjct: 1607 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1666
Query: 960 ERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVAD 1019
R +++L Q + E + LQ E+E LR L++ RKI E +E + +RV
Sbjct: 1667 LRSQEDLKE-QLAMVERRANLLQAEIEELRATLEQTERSRKIAE----QELLDASERVQL 1721
Query: 1020 LEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQ 1079
L +N L + K++L I S + M+ L+E R+ + K +
Sbjct: 1722 LHTQNTSLINTKKKLETDI-----------SQMQGEMEDILQEARNAEEKAKKAITDAAM 1770
Query: 1080 RYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKA 1139
+ L+ E ++N + D + L + E++ L+
Sbjct: 1771 MAEELKKEQDTSAHLERMKKN----------------MEQTVKDLQLRLDEAEQLALKGG 1814
Query: 1140 AMDMTVFLKLQKRVRELEQE---RKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLA 1196
+ KL+ RVRELE E +K + K ++ ++V+ QT+ D
Sbjct: 1815 KKQIQ---KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED-------R 1864
Query: 1197 YNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256
N L+ Q+L KL+ + ++ + Q+N++ + L ++L+ A E ++
Sbjct: 1865 KNILRLQDLVD---KLQAKVKSYKRQAEEAEEQSNTNLA---KFRKLQHELEEAEERADI 1918
Query: 1257 RKEEVLILRTQ 1267
+ +V LR +
Sbjct: 1919 AESQVNKLRVK 1929
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 564 bits (1454), Expect = e-160
Identities = 462/1608 (28%), Positives = 769/1608 (47%), Gaps = 191/1608 (11%)
Query: 11 TRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVG 70
T V++ +P E + + +EG K + ++ E L V+ +Q+ F NP
Sbjct: 36 TSVFVAEPKESFVKGTIQS--REGGK-VTVKTEGGATLT----VKDDQV-FPMNPPKYDK 87
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ +++LHEPAVL+NLK R+ + IYTY G+ V +NPY+ LP+Y +V+ Y G+
Sbjct: 88 IEDMAMMTHLHEPAVLYNLKERYA-AWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGK 146
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190
+ PHIF++++ AY+ M D +NQSI+++GESGAGKTV+ K ++YFAT+ + +
Sbjct: 147 KRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKK 206
Query: 191 N-----------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANM 239
+E+++++++P++EA GNAKT RNDNSSRFGK+I+I F + A++
Sbjct: 207 KEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
Query: 240 RTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELAL--TSAEDFFYTSQGGDTSIE 297
TYLLEKSRVVFQ ER+YHIFYQ+ + PE E+ L T+ D+ + SQG + S+
Sbjct: 267 ETYLLEKSRVVFQLKAERSYHIFYQITSNKK-PELIEMLLITTNPYDYPFVSQG-EISVA 324
Query: 298 GVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-------QAERDGDSCS 350
+DD E+ T A +LG ++SI+K+ +++H G++ QAE DG
Sbjct: 325 SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTE-- 382
Query: 351 ISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYA 410
++ + YL + + + + LC+ ++ +E K +++QV NA ALAK +Y
Sbjct: 383 VADKAAYLQS------LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYE 436
Query: 411 QLFGWIVEHINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHV 470
++F W+V IN+ L T + FIGVLDI GFE F+ NS EQ CIN+ NEKLQQ FN H+
Sbjct: 437 KMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHM 496
Query: 471 FKLEQEEYMKEQIPWTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLY 529
F LEQEEY KE I WT IDF D CI+LIE +GI +L+EEC PK TD ++ KLY
Sbjct: 497 FVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLY 556
Query: 530 DRH-SSSQHFQKPRM----SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASK 584
D+H S +FQKP++ + F ++H+A V+Y G+LEKN+D + E + + + S
Sbjct: 557 DQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSA 616
Query: 585 FPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLM 644
+A LF + T G+G+ A+ K + TV FR +L+ LM
Sbjct: 617 MKTLAQLFSGAQ-----TAEGEGAGG-----GAKKGGKKKGSSFQ-TVSALFRENLNKLM 665
Query: 645 ETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFF 704
L +T PH+VRCI PN+ K P + + + QLR GVLE IRI G+PSR Y DF
Sbjct: 666 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFK 725
Query: 705 NRYRVLVKKR--ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRAD 762
RY+VL E D K +L ++ D +++FG TK+FF+AG + LE++R D
Sbjct: 726 QRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDD 785
Query: 763 KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822
K +I +T Q CRG LAR + + R A+
Sbjct: 786 KLAQ---LITRT--------------------QARCRGFLARVEYQRMVERREAI----- 817
Query: 823 YRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQ---VLMEHKATTIQKHVRGWMARRH 879
+ +Q +++ V+ + F ++ + M+ + I+ + A+R
Sbjct: 818 FCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRK 877
Query: 880 FQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ-- 937
+ ++ + L+ + E + L + L + + +E K+ ++ + +++
Sbjct: 878 ELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEE 937
Query: 938 -NKEFKTLSEQLSVTTSTYTMEVERLKKEL--VHYQQSPGEDTSLRLQEEVESLRTELQR 994
N E +L S +++ L+ L V ++ E+ L EE+ L + +
Sbjct: 938 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 997
Query: 995 AHSERKILEDAHSREKDELR-----------------KRVAD----LEQENAL---LKDE 1030
E+K L++AH + D+L+ ++V D LEQE L L+
Sbjct: 998 LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERA 1057
Query: 1031 KEQLNNQILCQSKD----EFAQNSVKENLMKKE---------LEEERSRYQNLVKEYSQL 1077
K +L + + E + + E L KKE +E+E++ L K+ +L
Sbjct: 1058 KRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
Query: 1078 EQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDA---------- 1127
+ R + L +E I + + +S L + S E G A
Sbjct: 1118 QARIEELEEE--IEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175
Query: 1128 -----LQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSK-KVQAE 1181
+ +EE L+ A T+ K V EL ++ LQ +K E++ S+ K++ +
Sbjct: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235
Query: 1182 PPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYS 1241
++++ A + R LE + +LK+ E ++ + D Q +S
Sbjct: 1236 DLASNVETVSKAKGNLEKMCR-TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFS 1294
Query: 1242 LLLNQLKLAHEELEVRK----EEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKH 1297
L++ + +L K +++ L+ Q+ + + A +A + +
Sbjct: 1295 RQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYE 1354
Query: 1298 VDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEE 1357
+QE E + + N++ W E + + L++ + L +LQA EH E
Sbjct: 1355 EEQESKAELQRALSKANTEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQAAE-EHVEA 1412
Query: 1358 VEHLKAQLEALKEE---------------------MDKQQQTFCQTLL----LSPEAQVE 1392
V A LE K+ +DK+Q+ F + L E E
Sbjct: 1413 VNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE 1472
Query: 1393 FGVQQEISR-LTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRH 1451
Q+ +R L E +K E+ LK++ K ++ DL + +A+ ++ H
Sbjct: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL--TEQIAEGGKRIH 1530
Query: 1452 ELNR-QVTVQRKEKDFQGMLE------YHKEDEALLIRNLVTDLKPQM 1492
EL + + V++++ + Q LE H+E + L I+ + +K ++
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578
Score = 59.3 bits (142), Expect = 3e-08
Identities = 119/660 (18%), Positives = 282/660 (42%), Gaps = 66/660 (10%)
Query: 851 VRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML-KARRELKALRIE 909
+RR + ++H+AT + ++H + + I R+ K +E +++E
Sbjct: 1180 MRRDLEEATLQHEATAAT------LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1233
Query: 910 -----------ARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQ---LSVTTSTY 955
+++ +L+++ +E+++ +L+ K +EQ + L+ Q L + +
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEF 1293
Query: 956 TMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREK---DE 1012
+ +++ +KE + Q S G+ +++E L+ +L+ + L A + D
Sbjct: 1294 SRQLD--EKEALVSQLSRGKQA---FTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDL 1348
Query: 1013 LRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVK 1072
LR++ + ++ A L+ + N ++ Q + ++ ++++ +ELEE + + L +
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEV-AQWRTKYETDAIQRT---EELEEAKKK---LAQ 1401
Query: 1073 EYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVE 1132
E+ + + + +++T +N L+ + + + + + + ++
Sbjct: 1402 RLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT--NAACAALDKKQRNFDKIL 1459
Query: 1133 EIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKR-EQQDSKKVQAEPPQTDIDLDP 1191
+K QK R L E K++ E+ +Q ++ K + + Q +I D
Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS-DL 1518
Query: 1192 NADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL-A 1250
+A + ELE K+++ + EL+ A+ + G L LNQ+K
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578
Query: 1251 HEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVD---QEDAIEAY 1307
++ + EE+ L+ + + + +AE I +R+ +K ++ E I+
Sbjct: 1579 DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAE--IRSRNDAIRLKKKMEGDLNEMEIQLN 1636
Query: 1308 HGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEA 1367
H + Y N G LK L+ L++Q + +E++ ++ +
Sbjct: 1637 HANRMAAEALRN--YRNTQGI-------LKDTQIHLDDALRSQE-DLKEQLAMVERRANL 1686
Query: 1368 LKEEMDKQQQTFCQTLLLSPEAQVE-FGVQQEISRLTNENLDLKELVEKLEKNERKLKKQ 1426
L+ E+++ + T QT A+ E + + L +N L +KLE + +++ +
Sbjct: 1687 LQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGE 1746
Query: 1427 LKIYMKKAQDLE--AAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNL 1484
++ +++A++ E A +A+ + EL +KE+D LE K++ +++L
Sbjct: 1747 MEDILQEARNAEEKAKKAITDAAMMAEEL-------KKEQDTSAHLERMKKNMEQTVKDL 1799
Score = 47.8 bits (112), Expect = 1e-04
Identities = 78/371 (21%), Positives = 148/371 (39%), Gaps = 57/371 (15%)
Query: 906 LRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVT------TSTYTMEV 959
L E RS RL ME + +++ +++ N+ T T + +
Sbjct: 1607 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1666
Query: 960 ERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVAD 1019
R +++L Q + E + LQ E+E LR L++ RKI E +E + +RV
Sbjct: 1667 LRSQEDLKE-QLAMVERRANLLQAEIEELRATLEQTERSRKIAE----QELLDASERVQL 1721
Query: 1020 LEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQ 1079
L +N L + K++L I S + M+ L+E R+ + K +
Sbjct: 1722 LHTQNTSLINTKKKLETDI-----------SQMQGEMEDILQEARNAEEKAKKAITDAAM 1770
Query: 1080 RYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKA 1139
+ L+ E ++N + D + L + E++ L+
Sbjct: 1771 MAEELKKEQDTSAHLERMKKN----------------MEQTVKDLQLRLDEAEQLALKGG 1814
Query: 1140 AMDMTVFLKLQKRVRELEQE---RKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLA 1196
+ KL+ RVRELE E +K + K ++ ++V+ QT+ D
Sbjct: 1815 KKQIQ---KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEED-------R 1864
Query: 1197 YNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256
N L+ Q+L KL+ + ++ + Q+N++ + L ++L+ A E ++
Sbjct: 1865 KNILRLQDLVD---KLQAKVKSYKRQAEEAEEQSNTNLA---KFRKLQHELEEAEERADI 1918
Query: 1257 RKEEVLILRTQ 1267
+ +V LR +
Sbjct: 1919 AESQVNKLRVK 1929
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 558 bits (1439), Expect = e-158
Identities = 452/1509 (29%), Positives = 732/1509 (48%), Gaps = 145/1509 (9%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRL-EDETILEYPID-VQRNQLPFLRNPDILVG 70
VW+P + +A L EG++ ++ L E L P D +QR NP
Sbjct: 56 VWVPSELHGFEAAALRD---EGEEEAEVELAESGRRLRLPRDQIQR------MNPPKFSK 106
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V INPY+QLPIY + ++ Y G+
Sbjct: 107 AEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGK 165
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190
++ PH++AV E AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S
Sbjct: 166 KRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR 225
Query: 191 N-------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYL 243
+E ++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+GAN+ TYL
Sbjct: 226 KEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 285
Query: 244 LEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAE 303
LEKSR + QA DE ++HIFYQL AG +L L + + + G +S + E
Sbjct: 286 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSS--PGQERE 343
Query: 304 DFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCR 363
F++T ++ +LG +S+ ++++++L G++A++ ER+ D ++ P + CR
Sbjct: 344 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATM-PDNTAAQKLCR 402
Query: 364 LLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKA 423
LLG+ + L ++ + K + +Q A ALAK Y +LF W+V +N+A
Sbjct: 403 LLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRA 462
Query: 424 LHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQ 482
L S +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQEEY +E
Sbjct: 463 LDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 522
Query: 483 IPWTLIDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHF 538
IPWT +DF D QPCIDLIE G+L LLDEEC PK TD+++ +K+ F
Sbjct: 523 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKF 582
Query: 539 QKPR--MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDK 596
Q+PR F ++H+A KV+Y ++ +L KN D + + +L S L A+++ D
Sbjct: 583 QRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD-- 640
Query: 597 DPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVR 656
G ++S PP + +TVG ++ SL LM TL+ T P +VR
Sbjct: 641 ------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVR 694
Query: 657 CIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-E 715
CI PN EK +P+ + QLR GVLE IRI G+P+R + +F RY +L
Sbjct: 695 CIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIP 754
Query: 716 LANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTV 775
D K C +++ L DP+ ++ G++KIFFRAG +A LE+ R K + Q
Sbjct: 755 KGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 814
Query: 776 RGWLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAY 832
RG+L + K + + A +QR C +L R + +R+ +
Sbjct: 815 RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLR-------------HWQWWRLFTKVKPL 861
Query: 833 QRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQC 892
+V R V+QA RA +++ Q L + A + + ++G +A+ +R R A
Sbjct: 862 LQVTRQDEVLQA--RAQELQKV--QELQQQSAREVGE-LQGRVAQLEEERARLA------ 910
Query: 893 AFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTT 952
L+A EL A E R L +E V +L+ ++ E+ + S Q+
Sbjct: 911 --EQLRAEAELCAEAEETRG--RLAARKQELELVVSELEARVGEEEE----CSRQMQTEK 962
Query: 953 STYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAH---SRE 1009
++ L+ L E +LQ E + ++++ + +LED + S+E
Sbjct: 963 KRLQQHIQELEAHL-----EAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1017
Query: 1010 KDELRKRVADLEQENALLKDEKEQLNNQILCQSKD--EFAQNSVKENLMKKELEEERSRY 1067
+ L R+A+ + A +++ + LN L + KE ++ELE+ + R
Sbjct: 1018 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRL 1077
Query: 1068 ----QNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSL---ESDSNYPSISTSE 1120
L ++ + +QR + LR ++ R+ Q++L E + +
Sbjct: 1078 DGESSELQEQMVEQQQRAEELRAQL--------GRKEEELQAALARAEDEGGARAQLLKS 1129
Query: 1121 IGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQA 1180
+ + + AL + +E LE + T K +K+ R+L +E + L+ +LE + DS Q
Sbjct: 1130 LREAQAALAEAQE-DLESERVART---KAEKQRRDLGEELEALRGELE--DTLDSTNAQQ 1183
Query: 1181 EPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRK-------AVADQATQNNSS 1233
E L + LK+ LE E + + + ELR+ +A+Q Q
Sbjct: 1184 E-------LRSKREQEVTELKK-TLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1235
Query: 1234 HGSPDSYSLL-----------LNQLKLAHEELEVRKE--EVLILRTQIVSADQRRLAGRN 1280
G+ + L L+ L+ A +E E R+ E+ + Q + D R
Sbjct: 1236 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1295
Query: 1281 AEPNINARSSWPNSEKHVDQEDA--IEAYHGVCQTNSKTEDWGYLNEDG-----ELGLAY 1333
AE A++ N +++ ++ I + T ++ D L ++ LG
Sbjct: 1296 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1355
Query: 1334 QGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEF 1393
+ ++ A L QL+ ++ E L+ L E +Q++ + L +
Sbjct: 1356 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE---EAGALEAGEEARR 1412
Query: 1394 GVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHEL 1453
+E LT + E V++LE+ R+L+++L DLE + L + K+
Sbjct: 1413 RAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDLEQQRQLVSTLEKKQRK 1469
Query: 1454 NRQVTVQRK 1462
Q+ + K
Sbjct: 1470 FDQLLAEEK 1478
Score = 56.2 bits (134), Expect = 3e-07
Identities = 127/642 (19%), Positives = 260/642 (40%), Gaps = 93/642 (14%)
Query: 895 RMLKARRELKALRIEARSAEHL------KRLNVG-----MENKVVQLQRKIDEQNKEFKT 943
+ ++ +EL + + A+ L +L +G ME + L+ +++E+ +
Sbjct: 1319 KTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARER 1378
Query: 944 LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILE 1003
+L T E R ++E ++ GE+ R E E+L L LE
Sbjct: 1379 AGRELQ-TAQAQLSEWRRRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLE 1436
Query: 1004 DAHSREKDELRKRVADLEQENALLK--DEKEQLNNQILCQSKDEFAQNSVKENLMKKELE 1061
R + EL DLEQ+ L+ ++K++ +Q+L + K + + + E
Sbjct: 1437 RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGR 1496
Query: 1062 EERSRYQNLVKEYSQ-------LEQRYDNLRDEMTII---KQTPGHRRNPSNQSSLESDS 1111
E +R +L + + LE++ LR E+ + K G + ++ ++
Sbjct: 1497 EREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQ 1556
Query: 1112 NYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVREL-------EQERKKLQ 1164
+ +++ + ED L E+ K +++TV + R+L E+ R++L
Sbjct: 1557 AANDLR-AQVTELEDELTAAEDA---KLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA 1612
Query: 1165 VQLEKRE-QQDSKKVQ-----AEPPQTDIDLDP-NADLAYNSLKRQELESENKKLKNDLN 1217
QL E ++D ++ Q A + + +L+ A +A ++E + +K++ +
Sbjct: 1613 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1672
Query: 1218 ELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLA 1277
EL + V + T + +Q + + + L+ + EVL L+ ++ ++D+ R
Sbjct: 1673 ELWREVEETRTSREE----------IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQ 1722
Query: 1278 GRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLK 1337
+ + + N K E+ + + Q + E+ +E L Y+ L
Sbjct: 1723 AQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSE--LLNDRYRKLL 1780
Query: 1338 QVARLLEAQLQAQ---SLEHEEEVEHLKAQLEALKEEMDKQ------QQTFCQTLLLSPE 1388
L +L A+ S + E + L+ Q++ L+ + ++ + L S
Sbjct: 1781 LQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKL 1840
Query: 1389 AQVEFGVQQEI-SRLTNENL------DLKELVEKLEKNER-----------------KLK 1424
AQ E ++QE R+ + L LKE+V ++E+ R +LK
Sbjct: 1841 AQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLK 1900
Query: 1425 KQLKIYMKKAQDLEAAQALAQSE-----RKRHELNRQVTVQR 1461
+QL+ ++A +A + Q E +NR+VT R
Sbjct: 1901 RQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLR 1942
Score = 53.1 bits (126), Expect = 2e-06
Identities = 125/604 (20%), Positives = 236/604 (39%), Gaps = 73/604 (12%)
Query: 824 RMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKAT----------TIQKHVRG 873
++ A++ Q RA + + + RAM + +E +A T Q +
Sbjct: 1333 QLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSE 1392
Query: 874 WMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIE-ARSAEHLKRLNVG---MENKVVQ 929
W R+ +A + +A RE +AL A E + RL G ++ ++
Sbjct: 1393 WRRRQE----EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDD 1448
Query: 930 LQRKIDEQNKEFKTLSEQ-------LSVTTSTYTMEVERLKKELVHYQQSPGEDTSL-RL 981
+++Q + TL ++ L+ + VE ++ ++ SL R
Sbjct: 1449 ATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA 1508
Query: 982 QEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQI--- 1038
EE + R EL+R + + +A KD++ K V +LE+ + + L Q+
Sbjct: 1509 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 1568
Query: 1039 ---LCQSKDEFAQNSVKENLMKKELEEE--------RSRYQNLVKEYSQLEQRYDNLRDE 1087
L ++D + V +K + E + R + L K+ E D R +
Sbjct: 1569 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 1628
Query: 1088 MTII----KQTPGHRRNPSNQSSLESDSNYPSISTSEI--GDTEDALQQVEEIGLEKAAM 1141
T+ K+ G Q + ++ ++ ++VEE + +
Sbjct: 1629 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEI 1688
Query: 1142 DMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNAD-LAYNSL 1200
+ + +KR++ LE E +LQ E+ D + QA+ D D AD +A +L
Sbjct: 1689 -FSQNRESEKRLKGLEAEVLRLQ---EELAASDRARRQAQQ-----DRDEMADEVANGNL 1739
Query: 1201 KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE 1260
+ + E ++L+ L +L + + ++ Q+NS + D Y LL Q++ EL +
Sbjct: 1740 SKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLN-DRYRKLLLQVESLTTELSAERSF 1796
Query: 1261 VLILRT--QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTE 1318
+ Q + + L GR E + AR+ +H A+E+ + + E
Sbjct: 1797 SAKAESGRQQLERQIQELRGRLGEEDAGARA------RHKMTIAALESKLAQAEEQLEQE 1850
Query: 1319 DWGYLNEDGELGLAYQGLKQVA------RLLEAQLQAQSLEHEEEVEHLKAQLEALKEEM 1372
+ + A + LK+V R + QL+ Q + V+ LK QLE +EE
Sbjct: 1851 TRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEA 1910
Query: 1373 DKQQ 1376
+ Q
Sbjct: 1911 SRAQ 1914
Score = 47.8 bits (112), Expect = 1e-04
Identities = 120/610 (19%), Positives = 230/610 (37%), Gaps = 89/610 (14%)
Query: 898 KARRELKAL--RIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKT------------ 943
K R+EL+ L R++ S+E L+ V + + +L+ ++ + +E +
Sbjct: 1065 KGRQELEKLKRRLDGESSE-LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123
Query: 944 --LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKI 1001
L + L + E L+ E V ++ E L EE+E+LR EL+
Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERV--ARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1181
Query: 1002 LEDAHSREKDELRKRVADLEQENALLK---DEKEQLNNQILCQSKDEFAQNSVKENLMKK 1058
++ S+ + E+ + LE+E + + E Q + Q L + ++ Q + +K
Sbjct: 1182 QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1241
Query: 1059 -------ELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNP---------- 1101
E+ E R+ +L + EQR L ++ ++ G
Sbjct: 1242 TRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1301
Query: 1102 -----SNQSSLESDSNYPSISTS-EIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE 1155
N S +++ +I S E+ TE L +E+ E+ L L RVR
Sbjct: 1302 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK----LALGSRVRA 1357
Query: 1156 LEQERKKLQVQLEK------REQQDSKKVQAEPPQTDIDLDPNAD-LAYNSLKRQELESE 1208
+E E L+ QLE+ R ++ + QA+ + + A L R+ E
Sbjct: 1358 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1417
Query: 1209 NKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQI 1268
+ L L E + V D ++ L Q + LE ++ + L +
Sbjct: 1418 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1477
Query: 1269 VSA------DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGY 1322
+A ++ R E A S E+ + + +E + + +
Sbjct: 1478 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA----L 1533
Query: 1323 LNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQT 1382
L+ ++G + L++ R+ E + L+AQ+ L++E+ +
Sbjct: 1534 LSSKDDVGKSVHELERACRVAE-----------QAANDLRAQVTELEDELTAAEDA---- 1578
Query: 1383 LLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQA 1442
+ ++E VQ + T DL+ E E+ R+L KQL+ + + +
Sbjct: 1579 -----KLRLEVTVQ---ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1630
Query: 1443 LAQSERKRHE 1452
LA + RK+ E
Sbjct: 1631 LAVAARKKLE 1640
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 558 bits (1438), Expect = e-158
Identities = 477/1646 (28%), Positives = 781/1646 (47%), Gaps = 233/1646 (14%)
Query: 12 RVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGE 71
+ WIPD + + AE+ +G + ET + ++ +++ + P+ + E
Sbjct: 53 KCWIPDGENAYIEAEVKGSEDDGTVIV------ETADGESLSIKEDKIQQMNPPEFEMIE 106
Query: 72 NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQN 131
D+ L++L+E +VLH LK R+ + IYTY G+ V INPY+ LP+Y ++V+ Y G+
Sbjct: 107 -DMAMLTHLNEASVLHTLKRRYGQWM-IYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKR 164
Query: 132 MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191
+ PHIFAVA A++ M + +NQSI+ +GESGAGKTV++K+ ++YFAT+
Sbjct: 165 RSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRK 224
Query: 192 ----IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKS 247
+E++++ ++ I+EA GNAKT RNDNSSRFGK+I++ F R + ++ YLLEKS
Sbjct: 225 KQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKS 284
Query: 248 RVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAE--DFFYTSQGGDTSIEGVDDAEDF 305
RV+FQ ERNYHIFYQ+ + G E +L L SA DF + S G T +E +DDAE+
Sbjct: 285 RVIFQQAGERNYHIFYQILS--GQKELHDLLLVSANPSDFHFCSCGAVT-VESLDDAEEL 341
Query: 306 EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAI-QAERDGDSCSISPQDVYLSNFCRL 364
T QA +LG + +K+ +I+H G++ Q R+ + ++ + F L
Sbjct: 342 LATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAF--L 399
Query: 365 LGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKAL 424
+G+ S++ L H ++ +E + +++QV A AL+K +Y ++F W+V IN+AL
Sbjct: 400 MGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL 459
Query: 425 HTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484
L + FIG+LDI GFE E NS EQ CIN+ NEKLQQ FN H+F LEQEEY KE I
Sbjct: 460 DAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIE 519
Query: 485 WTLIDF-YDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQKPR 542
W I F D Q CIDLIE +GIL +L+EEC PK TD + KL+D H S H QKP+
Sbjct: 520 WVSIGFGLDLQACIDLIEKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPK 579
Query: 543 MS----NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598
F +VH+A V Y G+LEKN+D + E + + + S L+A LF
Sbjct: 580 PDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF------ 633
Query: 599 VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLH-----LLMETLNATTPH 653
+ +S SA P K+ KK Q SLH LM L +T PH
Sbjct: 634 ----------ENYMSTDSAIP---FGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPH 680
Query: 654 YVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVL--- 710
+VRCI PN K+P DP +QQLR GVLE RI G+P+R Y DF RY +L
Sbjct: 681 FVRCINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPR 740
Query: 711 -VKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATI 769
K + ++ K A +L +L D +++FG TK+FF+AG + LE +R ++
Sbjct: 741 TFPKSKFVSSRKAA--EELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFT 798
Query: 770 MIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRAR 829
+ Q +G L ++K+ ++ L A +++Q + R A
Sbjct: 799 LFQARAQGKLMRIKFQKI----------------------LEERDALILIQWNIRAFMAV 836
Query: 830 QAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIV 889
+ + + R I+ ++ V ++ + +QK + +R + + ++
Sbjct: 837 KNWPWM-RLFFKIKPLVKSSEVGEEVAG--LKEECAQLQKALEKSEFQREELKAKQVSLT 893
Query: 890 IQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQ---NKEFKTLSE 946
+ +L+ + E + L E L + + +E +V +L +++E+ N E
Sbjct: 894 QEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGR 953
Query: 947 QLSVTTSTYTMEVERLKKELV--HYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILED 1004
+L E++ L+ LV ++ E L EEVE L ++ + + K++++
Sbjct: 954 KLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE 1013
Query: 1005 AHSREKDEL---RKRVADLEQENALLKDEKEQLNNQILCQSKD----------------- 1044
AH + D+L ++++ L + N L+ + ++L + + K
Sbjct: 1014 AHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKL 1073
Query: 1045 --------EFAQNSVKENLMKKEL---------EEERSRYQNLVKEYSQLEQRYDNLRDE 1087
E +Q + E L KKEL E E+ L K +L+ + +L+++
Sbjct: 1074 NRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEK 1133
Query: 1088 MTIIKQTPG---HRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDM- 1143
+ + T R Q + + + S + E + + +E +K DM
Sbjct: 1134 LEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLE--ITKKQETKFQKLHRDME 1191
Query: 1144 -------TVFLKLQKR-----------VRELEQERKKLQ-----VQLE------KREQQD 1174
T L+KR V L+Q ++KL+ +QLE + EQ
Sbjct: 1192 EATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMT 1251
Query: 1175 SKKVQAEP---------PQTDIDLDPNADLAYN-SLKRQELESENKKLKNDLNELRKAVA 1224
K AE + LD LA + + ++ +L SE+ + L E ++A+
Sbjct: 1252 RAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEE-KEALI 1310
Query: 1225 DQATQNNSS------------HGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSAD 1272
+Q ++ S+ S S L + L+ A + ++ +E+ Q V A+
Sbjct: 1311 NQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQ--YEEEQEVKAE 1368
Query: 1273 QRRLAGRNAEPNINARSSWPNS--EKHVDQEDAIEAY----------HGVCQTNSKTEDW 1320
R + + R + N+ ++ D EDA + GV + + +
Sbjct: 1369 LHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLER 1428
Query: 1321 GYLNEDGELGLAYQGLKQV----ARLLEAQLQAQSL------EHEEEVEHLKA---QLEA 1367
ELG A L +V ARL + QLQ+ +HEE L A +++A
Sbjct: 1429 ARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQA 1488
Query: 1368 LKEEMDKQQQTFCQTLLLSPEAQVE-FGVQQEISRLTNE------NLDLKELVEKLEKNE 1420
L E+ K + T+ ++++ + E +Q+EIS LTN+ NL E V+KL + E
Sbjct: 1489 LSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEE 1548
Query: 1421 RKLKKQLKIYMKKAQ-------------DLEAAQALAQSERKRHELNRQV-TVQRKEKDF 1466
K ++++ +++ + LE +A A+ ERK E + ++ +RK++
Sbjct: 1549 ---KTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCT 1605
Query: 1467 QGMLEYHKEDEALLIRNLVTDLKPQM 1492
L+ + EA R VT LK +M
Sbjct: 1606 IDSLQSSLDSEA-KSRIEVTRLKKKM 1630
Score = 60.1 bits (144), Expect = 2e-08
Identities = 157/781 (20%), Positives = 309/781 (39%), Gaps = 120/781 (15%)
Query: 907 RIEARSAEHLKRLNVG--MENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKK 964
R+E L +L + E K +L R ++E F+T S L + E+E +
Sbjct: 1161 RLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVE 1220
Query: 965 ELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQEN 1024
L +Q +D S LQ EV+ L T +++ + E + ++ L + A L++
Sbjct: 1221 NLQQVKQKLEKDKS-DLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVT 1279
Query: 1025 ALLKD--------------------EKEQLNNQILCQSKDEFAQNSVKENLMKKELEEER 1064
L D EKE L NQ L + K F + ++ +LE+E
Sbjct: 1280 QLANDLAAQKTKLWSESGEFLRRLEEKEALINQ-LSREKSNFTRQIED---LRGQLEKET 1335
Query: 1065 SRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPG--HRR-NPSNQSSLESDSNYPSISTSEI 1121
L + ++ D LR++ ++ HR + N ++ Y +
Sbjct: 1336 KSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRT 1395
Query: 1122 GDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQL-----------EKR 1170
D EDA +++ I L++AA M V R LE+ R +LQ++L
Sbjct: 1396 EDLEDAKKELA-IRLQEAAEAMGV---ANARNASLERARHQLQLELGDALSDLGKVRSAA 1451
Query: 1171 EQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQN 1230
+ D K++Q+ D A ++E+++ + +L N +++ Q T
Sbjct: 1452 ARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLR 1511
Query: 1231 NSSHGSPDSYSLLLNQLKLAHEEL-EVRKEEVLI----LRTQIVSADQRRLAGRNAEPNI 1285
+ + S L NQ++ + L E+ K + LI Q+ + RN +
Sbjct: 1512 RENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKIL 1571
Query: 1286 NARSSWPNSEKHVDQ-----EDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQVA 1340
+ + ++ +++ ++ IE + Q + L+ + + + LK+
Sbjct: 1572 HFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQ-SSLDSEAKSRIEVTRLKKKM 1630
Query: 1341 R--LLEAQLQA-----QSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEF 1393
L E +LQ Q E + + L+ Q++ L+ ++D Q L+ + + +
Sbjct: 1631 EEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQ-------LNSDLKEQV 1683
Query: 1394 GVQQEISRLTNENL-DLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHE 1452
V + + L L DL+ L E+ E+ R +++L ++ S++K+ E
Sbjct: 1684 AVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLE 1743
Query: 1453 LNRQVTVQRKEKDFQGMLEYHKEDE------ALLIRNLVTDLKPQMLSGTVPCLPAYILY 1506
+ V R +K+ + +++ + E A+ NL +LK + +
Sbjct: 1744 AD----VARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDT------------ 1787
Query: 1507 MCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCLKQYSGD 1566
I H + T ++++ TI ++K L + M S +L +++ G+
Sbjct: 1788 --IAHLERTRENME------QTITDLQKRLAEAEQMALMGS--RKQIQKLESRVRELEGE 1837
Query: 1567 -EGFM-----TQNTAKQNEHCLKN--FDLTEYRQVLS---------DLSIQIYQQLIKIA 1609
EG + Q A++ E C+K + E ++ LS L +Q Y+Q +++A
Sbjct: 1838 LEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVA 1897
Query: 1610 E 1610
E
Sbjct: 1898 E 1898
Score = 54.7 bits (130), Expect = 8e-07
Identities = 110/546 (20%), Positives = 240/546 (43%), Gaps = 65/546 (11%)
Query: 905 ALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEV---ER 961
A R++ + + K L + K + Q +D KE + LS +L +TY + E
Sbjct: 1451 AARLDQKQLQSGKAL-ADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQET 1509
Query: 962 LKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE 1021
L++E + Q+ T+ +++E ++L TE+++ +K++E+ EK E++ + E
Sbjct: 1510 LRRENKNLQEEISNLTN-QVREGTKNL-TEMEKV---KKLIEE----EKTEVQVTLE--E 1558
Query: 1022 QENALLKDEKEQLNNQI-LCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQR 1080
E AL ++E + L+ Q+ L ++K E + +++ +E+E R + Q +
Sbjct: 1559 TEGALERNESKILHFQLELLEAKAELERKLSEKD---EEIENFRRKQQCTIDSLQSSLDS 1615
Query: 1081 YDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAA 1140
R E+T +K+ N + L + S +T +G + Q++++ ++
Sbjct: 1616 EAKSRIEVTRLKKKMEEDLNEM-ELQLSCANRQVSEATKSLGQLQI---QIKDLQMQ--- 1668
Query: 1141 MDMTVFLK--LQKRVRELEQERKKLQVQLE--KREQQDSKKVQAEPPQTDIDLDPNADLA 1196
+D + L L+++V E+ LQ +LE + Q+ +++ + + ++ +L
Sbjct: 1669 LDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLF 1728
Query: 1197 YNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEV 1256
Y + L S+ KKL+ D+ ++K + + ++ ++ L EEL+
Sbjct: 1729 YT--QNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLS---EELKK 1783
Query: 1257 RKEEVLILRT------QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGV 1310
+++ + L Q ++ Q+RLA + +R E V + +
Sbjct: 1784 KQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEG------- 1836
Query: 1311 CQTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKE 1370
E G + E A +G +++ R ++ +L Q+ E ++ + ++ Q++ L+
Sbjct: 1837 -------ELEGEIRRSAE---AQRGARRLERCIK-ELTYQAEEDKKNLSRMQTQMDKLQL 1885
Query: 1371 EMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIY 1430
++ +Q Q + +A ++ NE +KE E E KLK + + +
Sbjct: 1886 KVQNYKQ---QVEVAETQANQYLSKYKKQQHELNE---VKERAEVAESQVNKLKIKAREF 1939
Query: 1431 MKKAQD 1436
KK Q+
Sbjct: 1940 GKKVQE 1945
Score = 31.2 bits (69), Expect = 9.8
Identities = 29/160 (18%), Positives = 66/160 (41%), Gaps = 22/160 (13%)
Query: 897 LKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE--------QNKEFKTLSEQL 948
++A + L+ + + HL+R ME + LQ+++ E K+ + L ++
Sbjct: 1772 IEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRV 1831
Query: 949 -------------SVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRA 995
S +ER KEL YQ + R+Q +++ L+ ++Q
Sbjct: 1832 RELEGELEGEIRRSAEAQRGARRLERCIKELT-YQAEEDKKNLSRMQTQMDKLQLKVQNY 1890
Query: 996 HSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLN 1035
+ ++ E ++ + +K+ +L + + + Q+N
Sbjct: 1891 KQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVN 1930
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 557 bits (1435), Expect = e-158
Identities = 453/1517 (29%), Positives = 733/1517 (48%), Gaps = 153/1517 (10%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRL-EDETILEYPID-VQRNQLPFLRNPDILVG 70
VW+P + +A L EG++ ++ L E L P D +QR NP
Sbjct: 56 VWVPSELHGFEAAALRD---EGEEEAEVELAESGRRLRLPRDQIQR------MNPPKFSK 106
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V INPY+QLPIY + ++ Y G+
Sbjct: 107 AEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGK 165
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---- 186
++ PH++AV E AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S
Sbjct: 166 KRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR 225
Query: 187 -----------ASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHII 235
S +E ++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+
Sbjct: 226 KEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIV 285
Query: 236 GANMRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTS 295
GAN+ TYLLEKSR + QA DE ++HIFYQL AG +L L + + + G +S
Sbjct: 286 GANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSS 345
Query: 296 IEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQD 355
+ E F++T ++ +LG +S+ ++++++L G++A++ ER+ D ++ P +
Sbjct: 346 --PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATM-PDN 402
Query: 356 VYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGW 415
CRLLG+ + L ++ + K + +Q A ALAK Y +LF W
Sbjct: 403 TAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRW 462
Query: 416 IVEHINKALHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLE 474
+V +N+AL S +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LE
Sbjct: 463 LVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLE 522
Query: 475 QEEYMKEQIPWTLIDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYD 530
QEEY +E IPWT +DF D QPCIDLIE G+L LLDEEC PK TD+++ +K+
Sbjct: 523 QEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQ 582
Query: 531 RHSSSQHFQKPR--MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLV 588
FQ+PR F ++H+A KV+Y ++ +L KN D + + +L S L
Sbjct: 583 EQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLT 642
Query: 589 ADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLN 648
A+++ D G ++S PP + +TVG ++ SL LM TL+
Sbjct: 643 AEIWKD--------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLS 694
Query: 649 ATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYR 708
T P +VRCI PN EK +P+ + QLR GVLE IRI G+P+R + +F RY
Sbjct: 695 NTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYE 754
Query: 709 VLVKKR-ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTA 767
+L D K C +++ L DP+ ++ G++KIFFRAG +A LE+ R K
Sbjct: 755 ILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDI 814
Query: 768 TIMIQKTVRGWLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYR 824
+ Q RG+L + K + + A +QR C +L R + +R
Sbjct: 815 IVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLR-------------HWQWWR 861
Query: 825 MQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLR 884
+ + +V R V+QA RA +++ Q L + A + + ++G +A+ +R R
Sbjct: 862 LFTKVKPLLQVTRQDEVLQA--RAQELQKV--QELQQQSAREVGE-LQGRVAQLEEERAR 916
Query: 885 DAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTL 944
A L+A EL A E R L +E V +L+ ++ E+ +
Sbjct: 917 LA--------EQLRAEAELCAEAEETRG--RLAARKQELELVVSELEARVGEEEE----C 962
Query: 945 SEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILED 1004
S Q+ ++ L+ L E +LQ E + ++++ + +LED
Sbjct: 963 SRQMQTEKKRLQQHIQELEAHL-----EAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED 1017
Query: 1005 AH---SREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKD--EFAQNSVKENLMKKE 1059
+ S+E+ L R+A+ + A +++ + LN L + KE ++E
Sbjct: 1018 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE 1077
Query: 1060 LEEERSRY----QNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSL---ESDSN 1112
LE+ + R L ++ + +QR + LR ++ R+ Q++L E +
Sbjct: 1078 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQL--------GRKEEELQAALARAEDEGG 1129
Query: 1113 YPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQ 1172
+ + + + AL + +E LE + T K +K+ R+L +E + L+ +LE +
Sbjct: 1130 ARAQLLKSLREAQAALAEAQE-DLESERVART---KAEKQRRDLGEELEALRGELE--DT 1183
Query: 1173 QDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRK-------AVAD 1225
DS Q E L + LK+ LE E + + + ELR+ +A+
Sbjct: 1184 LDSTNAQQE-------LRSKREQEVTELKK-TLEEETRIHEAAVQELRQRHGQALGELAE 1235
Query: 1226 QATQNNSSHGSPDSYSLL-----------LNQLKLAHEELEVRKE--EVLILRTQIVSAD 1272
Q Q G+ + L L+ L+ A +E E R+ E+ + Q + D
Sbjct: 1236 QLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD 1295
Query: 1273 QRRLAGRNAEPNINARSSWPNSEKHVDQEDA--IEAYHGVCQTNSKTEDWGYLNEDG--- 1327
R AE A++ N +++ ++ I + T ++ D L ++
Sbjct: 1296 GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 1355
Query: 1328 --ELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLL 1385
LG + ++ A L QL+ ++ E L+ L E +Q++ + L
Sbjct: 1356 KLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE---EAGAL 1412
Query: 1386 SPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQ 1445
+ +E LT + E V++LE+ R+L+++L DLE + L
Sbjct: 1413 EAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDLEQQRQLVS 1469
Query: 1446 SERKRHELNRQVTVQRK 1462
+ K+ Q+ + K
Sbjct: 1470 TLEKKQRKFDQLLAEEK 1486
Score = 56.2 bits (134), Expect = 3e-07
Identities = 127/642 (19%), Positives = 260/642 (40%), Gaps = 93/642 (14%)
Query: 895 RMLKARRELKALRIEARSAEHL------KRLNVG-----MENKVVQLQRKIDEQNKEFKT 943
+ ++ +EL + + A+ L +L +G ME + L+ +++E+ +
Sbjct: 1327 KTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARER 1386
Query: 944 LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILE 1003
+L T E R ++E ++ GE+ R E E+L L LE
Sbjct: 1387 AGRELQ-TAQAQLSEWRRRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLE 1444
Query: 1004 DAHSREKDELRKRVADLEQENALLK--DEKEQLNNQILCQSKDEFAQNSVKENLMKKELE 1061
R + EL DLEQ+ L+ ++K++ +Q+L + K + + + E
Sbjct: 1445 RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGR 1504
Query: 1062 EERSRYQNLVKEYSQ-------LEQRYDNLRDEMTII---KQTPGHRRNPSNQSSLESDS 1111
E +R +L + + LE++ LR E+ + K G + ++ ++
Sbjct: 1505 EREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQ 1564
Query: 1112 NYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVREL-------EQERKKLQ 1164
+ +++ + ED L E+ K +++TV + R+L E+ R++L
Sbjct: 1565 AANDLR-AQVTELEDELTAAEDA---KLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA 1620
Query: 1165 VQLEKRE-QQDSKKVQ-----AEPPQTDIDLDP-NADLAYNSLKRQELESENKKLKNDLN 1217
QL E ++D ++ Q A + + +L+ A +A ++E + +K++ +
Sbjct: 1621 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1680
Query: 1218 ELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLA 1277
EL + V + T + +Q + + + L+ + EVL L+ ++ ++D+ R
Sbjct: 1681 ELWREVEETRTSREE----------IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQ 1730
Query: 1278 GRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLK 1337
+ + + N K E+ + + Q + E+ +E L Y+ L
Sbjct: 1731 AQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSE--LLNDRYRKLL 1788
Query: 1338 QVARLLEAQLQAQ---SLEHEEEVEHLKAQLEALKEEMDKQ------QQTFCQTLLLSPE 1388
L +L A+ S + E + L+ Q++ L+ + ++ + L S
Sbjct: 1789 LQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKL 1848
Query: 1389 AQVEFGVQQEI-SRLTNENL------DLKELVEKLEKNER-----------------KLK 1424
AQ E ++QE R+ + L LKE+V ++E+ R +LK
Sbjct: 1849 AQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLK 1908
Query: 1425 KQLKIYMKKAQDLEAAQALAQSE-----RKRHELNRQVTVQR 1461
+QL+ ++A +A + Q E +NR+VT R
Sbjct: 1909 RQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLR 1950
Score = 53.1 bits (126), Expect = 2e-06
Identities = 125/604 (20%), Positives = 236/604 (39%), Gaps = 73/604 (12%)
Query: 824 RMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKAT----------TIQKHVRG 873
++ A++ Q RA + + + RAM + +E +A T Q +
Sbjct: 1341 QLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSE 1400
Query: 874 WMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIE-ARSAEHLKRLNVG---MENKVVQ 929
W R+ +A + +A RE +AL A E + RL G ++ ++
Sbjct: 1401 WRRRQE----EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDD 1456
Query: 930 LQRKIDEQNKEFKTLSEQ-------LSVTTSTYTMEVERLKKELVHYQQSPGEDTSL-RL 981
+++Q + TL ++ L+ + VE ++ ++ SL R
Sbjct: 1457 ATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA 1516
Query: 982 QEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQI--- 1038
EE + R EL+R + + +A KD++ K V +LE+ + + L Q+
Sbjct: 1517 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 1576
Query: 1039 ---LCQSKDEFAQNSVKENLMKKELEEE--------RSRYQNLVKEYSQLEQRYDNLRDE 1087
L ++D + V +K + E + R + L K+ E D R +
Sbjct: 1577 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 1636
Query: 1088 MTII----KQTPGHRRNPSNQSSLESDSNYPSISTSEI--GDTEDALQQVEEIGLEKAAM 1141
T+ K+ G Q + ++ ++ ++VEE + +
Sbjct: 1637 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEI 1696
Query: 1142 DMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNAD-LAYNSL 1200
+ + +KR++ LE E +LQ E+ D + QA+ D D AD +A +L
Sbjct: 1697 -FSQNRESEKRLKGLEAEVLRLQ---EELAASDRARRQAQQ-----DRDEMADEVANGNL 1747
Query: 1201 KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE 1260
+ + E ++L+ L +L + + ++ Q+NS + D Y LL Q++ EL +
Sbjct: 1748 SKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLN-DRYRKLLLQVESLTTELSAERSF 1804
Query: 1261 VLILRT--QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTE 1318
+ Q + + L GR E + AR+ +H A+E+ + + E
Sbjct: 1805 SAKAESGRQQLERQIQELRGRLGEEDAGARA------RHKMTIAALESKLAQAEEQLEQE 1858
Query: 1319 DWGYLNEDGELGLAYQGLKQVA------RLLEAQLQAQSLEHEEEVEHLKAQLEALKEEM 1372
+ + A + LK+V R + QL+ Q + V+ LK QLE +EE
Sbjct: 1859 TRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEA 1918
Query: 1373 DKQQ 1376
+ Q
Sbjct: 1919 SRAQ 1922
Score = 47.8 bits (112), Expect = 1e-04
Identities = 120/610 (19%), Positives = 230/610 (37%), Gaps = 89/610 (14%)
Query: 898 KARRELKAL--RIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKT------------ 943
K R+EL+ L R++ S+E L+ V + + +L+ ++ + +E +
Sbjct: 1073 KGRQELEKLKRRLDGESSE-LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131
Query: 944 --LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKI 1001
L + L + E L+ E V ++ E L EE+E+LR EL+
Sbjct: 1132 AQLLKSLREAQAALAEAQEDLESERV--ARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1189
Query: 1002 LEDAHSREKDELRKRVADLEQENALLK---DEKEQLNNQILCQSKDEFAQNSVKENLMKK 1058
++ S+ + E+ + LE+E + + E Q + Q L + ++ Q + +K
Sbjct: 1190 QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1249
Query: 1059 -------ELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNP---------- 1101
E+ E R+ +L + EQR L ++ ++ G
Sbjct: 1250 TRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1309
Query: 1102 -----SNQSSLESDSNYPSISTS-EIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE 1155
N S +++ +I S E+ TE L +E+ E+ L L RVR
Sbjct: 1310 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK----LALGSRVRA 1365
Query: 1156 LEQERKKLQVQLEK------REQQDSKKVQAEPPQTDIDLDPNAD-LAYNSLKRQELESE 1208
+E E L+ QLE+ R ++ + QA+ + + A L R+ E
Sbjct: 1366 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1425
Query: 1209 NKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQI 1268
+ L L E + V D ++ L Q + LE ++ + L +
Sbjct: 1426 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1485
Query: 1269 VSA------DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGY 1322
+A ++ R E A S E+ + + +E + + +
Sbjct: 1486 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA----L 1541
Query: 1323 LNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQT 1382
L+ ++G + L++ R+ E + L+AQ+ L++E+ +
Sbjct: 1542 LSSKDDVGKSVHELERACRVAE-----------QAANDLRAQVTELEDELTAAEDA---- 1586
Query: 1383 LLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQA 1442
+ ++E VQ + T DL+ E E+ R+L KQL+ + + +
Sbjct: 1587 -----KLRLEVTVQ---ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1638
Query: 1443 LAQSERKRHE 1452
LA + RK+ E
Sbjct: 1639 LAVAARKKLE 1648
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 555 bits (1431), Expect = e-157
Identities = 341/999 (34%), Positives = 546/999 (54%), Gaps = 75/999 (7%)
Query: 7 YSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPD 66
+++ TRVW+ + + + S EG + R + + Y +Q +P
Sbjct: 5 FTEGTRVWLRENGQHFPST--VNSCAEG--IVVFRTDYGQVFTYKQSTITHQKVTAMHPT 60
Query: 67 ILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP-IYGQDVIY 125
G +D+ +L+ LH ++++NL R+ + N IYTY G +L ++NPY+ + +Y +
Sbjct: 61 NEEGVDDMASLTELHGGSIMYNLFQRY-KRNQIYTYIGSILASVNPYQPIAGLYEPATME 119
Query: 126 TYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGG 185
YS +++G++ PHIFA+A E Y+ + + NQ I++SGESGAGKT S K +++ + +
Sbjct: 120 QYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQ 179
Query: 186 SASETNIEEK-------VLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGAN 238
+ E +++EK +L SSPIMEA GNAKT N+NSSRFGK++Q+ ++ +I G
Sbjct: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
Query: 239 MRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEG 298
+ YLLEK+RVV Q ERNYHIFY L A E +E L++ E++ Y +Q G +
Sbjct: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKT 299
Query: 299 VDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYL 358
+ D E F + A ++ + + +++A ILHLG++ G S L
Sbjct: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF-ITAGGAQVSFKTA---L 355
Query: 359 SNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVE 418
LLG++ +Q+ L R + E + +++QQ +++R++LA +YA F W+++
Sbjct: 356 GRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIK 415
Query: 419 HINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEY 478
IN + + + IG+LDI+GFE FEVN FEQF INYANEKLQ+ FN H+F LEQ EY
Sbjct: 416 KINSRIKGN-EDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEY 474
Query: 479 MKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHF 538
+E + W ID+ DN C+DLIE KLG+L L++EE P+ TD +KL+ +H+++ +
Sbjct: 475 SREGLVWEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANNHFY 534
Query: 539 QKPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598
KPR++ F + H+A +V+Y G LEKNRDT ++ +N+L+ S+F + DLF
Sbjct: 535 VKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLF------ 588
Query: 599 VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCI 658
+S R+ + +K +K + TV QF+ SLH LM TL+++ P +VRCI
Sbjct: 589 -----------EHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCI 637
Query: 659 KPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELAN 718
KPN +K+P FD + QLR G+LET+RI AGY R + DF+ RY+VL++ L
Sbjct: 638 KPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE 697
Query: 719 TDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGW 778
D + C S+L+ ++Q G+TK+F R LEK R ++ A ++I+ V G+
Sbjct: 698 -DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGF 756
Query: 779 LQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRA 838
L + +Y ++ YC V++QK+YR R+ + +++A
Sbjct: 757 LARKQYRKV--------LYC-----------------VVIIQKNYRAFLLRRRFLHLKKA 791
Query: 839 AVVIQAFTRAMFVRRTYRQVLME-------HKATTIQKHVRGWMARRHFQRLRDAAIVIQ 891
A+V Q R RR YRQ+L E K +K R R + R+A + Q
Sbjct: 792 AIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQ 851
Query: 892 CAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQ--LS 949
K ++EL+AL+ + AE + L ENK V+ +++++ ++ + + EQ LS
Sbjct: 852 QEEETRK-QQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELS 910
Query: 950 VTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESL 988
+T ++ ER +EL + E+ QE +ESL
Sbjct: 911 LTEASLQKLQERRDQELRRLE----EEACRAAQEFLESL 945
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/350 (24%), Positives = 153/350 (43%), Gaps = 57/350 (16%)
Query: 726 RSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKY- 784
R + N+ K PD QF + + Q+ Y L + R A +++ + + ++ K
Sbjct: 635 RCIKPNMQKMPD--QFDQAVVL---NQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVL 689
Query: 785 -------HRLKG-ATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVR 836
++G T LQ Y + +L + V L++ + ++ + V
Sbjct: 690 MRNLALPEDVRGKCTSLLQLYDASNSEWQLG------KTKVFLRESLEQKLEKRREEEVS 743
Query: 837 RAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRM 896
AA+VI+A R+ YR+VL + IQK+ R ++ RR F L+ AAIV Q R
Sbjct: 744 HAAMVIRAHVLGFLARKQYRKVL--YCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRG 801
Query: 897 LKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYT 956
ARR + L E R E K+ + + ++K +E+ +E
Sbjct: 802 QIARRVYRQLLAEKREQEEKKK-------QEEEEKKKREEEERE---------------- 838
Query: 957 MEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKR 1016
E ER + EL Q+ E+T R Q+E+E+L+ + A R++ + +++ +E+ +
Sbjct: 839 RERERREAELRAQQE---EET--RKQQELEALQKSQKEAELTRELEKQKENKQVEEILR- 892
Query: 1017 VADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSR 1066
LE+E L+ KEQ + S + + +E + LEEE R
Sbjct: 893 ---LEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE---LRRLEEEACR 936
Score = 41.6 bits (96), Expect = 0.007
Identities = 42/163 (25%), Positives = 84/163 (51%), Gaps = 15/163 (9%)
Query: 1338 QVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQ 1397
Q+AR + QL A+ E EE+ + + + + +EE +++++ + L + + E QQ
Sbjct: 802 QIARRVYRQLLAEKREQEEKKKQEEEEKKK-REEEERERERERREAELRAQQEEETRKQQ 860
Query: 1398 EISRL--TNENLDLKELVEKLEKNER-----KLKKQLKIY--MKKAQDLEAAQALAQ--S 1446
E+ L + + +L +EK ++N++ +L+K+++ MK+ Q+L +A Q
Sbjct: 861 ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ 920
Query: 1447 ERKRHELNR-QVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDL 1488
ER+ EL R + R ++F L + + DE +RN+ L
Sbjct: 921 ERRDQELRRLEEEACRAAQEFLESLNFDEIDEC--VRNIERSL 961
Score = 36.2 bits (82), Expect = 0.30
Identities = 48/230 (20%), Positives = 90/230 (39%), Gaps = 71/230 (30%)
Query: 856 RQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEH 915
R+ + H A I+ HV G++AR+ ++++ ++IQ +R RR H
Sbjct: 738 REEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFL----------H 787
Query: 916 LKRLNVGMENKVV-QLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPG 974
LK+ + + ++ Q+ R++ Q L+E+ E E KK+
Sbjct: 788 LKKAAIVFQKQLRGQIARRVYRQ-----LLAEK---------REQEEKKKQ--------- 824
Query: 975 EDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQL 1034
+EE + R E +R + + +++++E RK
Sbjct: 825 -------EEEEKKKREEEERERERERREAELRAQQEEETRK------------------- 858
Query: 1035 NNQILCQSKDEFAQNSVKENLMKKELEEERSRYQ-----NLVKEYSQLEQ 1079
Q + E Q S KE + +ELE+++ Q L KE L++
Sbjct: 859 ------QQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQR 902
Score = 33.1 bits (74), Expect = 2.6
Identities = 32/142 (22%), Positives = 64/142 (45%), Gaps = 7/142 (4%)
Query: 1041 QSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQR-YDNLRDEMTIIKQTPGHRR 1099
Q + + A+ ++ L +K +EE+ + + K+ + E+R + R E + Q R
Sbjct: 798 QLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETR 857
Query: 1100 NPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQE 1159
+L+ + T E+ ++ Q E + LEK D L+ K +EL
Sbjct: 858 KQQELEALQKSQKEAEL-TRELEKQKENKQVEEILRLEKEIED----LQRMKEQQELSLT 912
Query: 1160 RKKLQVQLEKREQQDSKKVQAE 1181
LQ +L++R Q+ ++++ E
Sbjct: 913 EASLQ-KLQERRDQELRRLEEE 933
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 554 bits (1427), Expect = e-157
Identities = 458/1542 (29%), Positives = 738/1542 (47%), Gaps = 170/1542 (11%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRL-EDETILEYPID-VQRNQLPFLRNPDILVG 70
VW+P + +A L EG++ ++ L E L P D +QR NP
Sbjct: 56 VWVPSELHGFEAAALRD---EGEEEAEVELAESGRRLRLPRDQIQR------MNPPKFSK 106
Query: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V INPY+QLPIY + ++ Y G+
Sbjct: 107 AEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGK 165
Query: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---- 186
++ PH++AV E AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S
Sbjct: 166 KRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR 225
Query: 187 -----------ASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHII 235
S +E ++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+
Sbjct: 226 KEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIV 285
Query: 236 GANMRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTS 295
GAN+ TYLLEKSR + QA DE ++HIFYQL AG +L L + + + G +S
Sbjct: 286 GANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSS 345
Query: 296 IEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQD 355
+ E F++T ++ +LG +S+ ++++++L G++A++ ER+ D ++ P +
Sbjct: 346 --PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATM-PDN 402
Query: 356 VYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGW 415
CRLLG+ + L ++ + K + +Q A ALAK Y +LF W
Sbjct: 403 TAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRW 462
Query: 416 IVEHINKALHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLE 474
+V +N+AL S +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LE
Sbjct: 463 LVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLE 522
Query: 475 QEEYMKEQIPWTLIDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYD 530
QEEY +E IPWT +DF D QPCIDLIE G+L LLDEEC PK TD+++ +K+
Sbjct: 523 QEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQ 582
Query: 531 RHSSSQHFQKPR--MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLV 588
FQ+PR F ++H+A KV+Y ++ +L KN D + + +L S L
Sbjct: 583 EQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLT 642
Query: 589 ADLFHDDK---------DPVPATTPGKGS--SSKISVRSAR--------------PPMKV 623
A+++ D+ P + PG SS IS PP
Sbjct: 643 AEIWKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGR 702
Query: 624 SNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGV 683
+ +TVG ++ SL LM TL+ T P +VRCI PN EK +P+ + QLR GV
Sbjct: 703 PRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGV 762
Query: 684 LETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELANTDKKAICRSVLENLIKDPDKFQFG 742
LE IRI G+P+R + +F RY +L D K C +++ L DP+ ++ G
Sbjct: 763 LEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVG 822
Query: 743 RTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQK---VKYHRLKGATLTLQRYCR 799
++KIFFRAG +A LE+ R K + Q RG+L + K + + A +QR C
Sbjct: 823 QSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCA 882
Query: 800 GHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVL 859
+L R + +R+ + +V R V+QA RA +++ Q L
Sbjct: 883 AYLKLR-------------HWQWWRLFTKVKPLLQVTRQDEVLQA--RAQELQKV--QEL 925
Query: 860 MEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRL 919
+ A + + ++G +A+ +R R A L+A EL A E R L
Sbjct: 926 QQQSAREVGE-LQGRVAQLEEERARLA--------EQLRAEAELCAEAEETRG--RLAAR 974
Query: 920 NVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSL 979
+E V +L+ ++ E+ + S Q+ ++ L+ L E
Sbjct: 975 KQELELVVSELEARVGEEEE----CSRQMQTEKKRLQQHIQELEAHL-----EAEEGARQ 1025
Query: 980 RLQEEVESLRTELQRAHSERKILEDAH---SREKDELRKRVADLEQENALLKDEKEQLNN 1036
+LQ E + ++++ + +LED + S+E+ L R+A+ + A +++ + LN
Sbjct: 1026 KLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1085
Query: 1037 QILCQSKD--EFAQNSVKENLMKKELEEERSRY----QNLVKEYSQLEQRYDNLRDEMTI 1090
L + KE ++ELE+ + R L ++ + +QR + LR ++
Sbjct: 1086 LRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQL-- 1143
Query: 1091 IKQTPGHRRNPSNQSSL---ESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFL 1147
R+ Q++L E + + + + + AL + +E LE + T
Sbjct: 1144 ------GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE-DLESERVART--- 1193
Query: 1148 KLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELES 1207
K +K+ R+L +E + L+ +LE + DS Q E L + LK+ LE
Sbjct: 1194 KAEKQRRDLGEELEALRGELE--DTLDSTNAQQE-------LRSKREQEVTELKK-TLEE 1243
Query: 1208 ENKKLKNDLNELRK-------AVADQATQNNSSHGSPDSYSLL-----------LNQLKL 1249
E + + + ELR+ +A+Q Q G+ + L L+ L+
Sbjct: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
Query: 1250 AHEELEVRKE--EVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDA--IE 1305
A +E E R+ E+ + Q + D R AE A++ N +++ ++ I
Sbjct: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
Query: 1306 AYHGVCQTNSKTEDWGYLNEDG-----ELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEH 1360
+ T ++ D L ++ LG + ++ A L QL+ ++ E
Sbjct: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
Query: 1361 LKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNE 1420
L+ L E +Q++ + L + +E LT + E V++LE+
Sbjct: 1424 LQTAQAQLSEWRRRQEE---EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGR 1480
Query: 1421 RKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRK 1462
R+L+++L DLE + L + K+ Q+ + K
Sbjct: 1481 RRLQQELD---DATMDLEQQRQLVSTLEKKQRKFDQLLAEEK 1519
Score = 56.2 bits (134), Expect = 3e-07
Identities = 127/642 (19%), Positives = 260/642 (40%), Gaps = 93/642 (14%)
Query: 895 RMLKARRELKALRIEARSAEHL------KRLNVG-----MENKVVQLQRKIDEQNKEFKT 943
+ ++ +EL + + A+ L +L +G ME + L+ +++E+ +
Sbjct: 1360 KTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARER 1419
Query: 944 LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILE 1003
+L T E R ++E ++ GE+ R E E+L L LE
Sbjct: 1420 AGRELQ-TAQAQLSEWRRRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLE 1477
Query: 1004 DAHSREKDELRKRVADLEQENALLK--DEKEQLNNQILCQSKDEFAQNSVKENLMKKELE 1061
R + EL DLEQ+ L+ ++K++ +Q+L + K + + + E
Sbjct: 1478 RGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGR 1537
Query: 1062 EERSRYQNLVKEYSQ-------LEQRYDNLRDEMTII---KQTPGHRRNPSNQSSLESDS 1111
E +R +L + + LE++ LR E+ + K G + ++ ++
Sbjct: 1538 EREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQ 1597
Query: 1112 NYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVREL-------EQERKKLQ 1164
+ +++ + ED L E+ K +++TV + R+L E+ R++L
Sbjct: 1598 AANDLR-AQVTELEDELTAAEDA---KLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA 1653
Query: 1165 VQLEKRE-QQDSKKVQ-----AEPPQTDIDLDP-NADLAYNSLKRQELESENKKLKNDLN 1217
QL E ++D ++ Q A + + +L+ A +A ++E + +K++ +
Sbjct: 1654 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1713
Query: 1218 ELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLA 1277
EL + V + T + +Q + + + L+ + EVL L+ ++ ++D+ R
Sbjct: 1714 ELWREVEETRTSREE----------IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQ 1763
Query: 1278 GRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLK 1337
+ + + N K E+ + + Q + E+ +E L Y+ L
Sbjct: 1764 AQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSE--LLNDRYRKLL 1821
Query: 1338 QVARLLEAQLQAQ---SLEHEEEVEHLKAQLEALKEEMDKQ------QQTFCQTLLLSPE 1388
L +L A+ S + E + L+ Q++ L+ + ++ + L S
Sbjct: 1822 LQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKL 1881
Query: 1389 AQVEFGVQQEI-SRLTNENL------DLKELVEKLEKNER-----------------KLK 1424
AQ E ++QE R+ + L LKE+V ++E+ R +LK
Sbjct: 1882 AQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLK 1941
Query: 1425 KQLKIYMKKAQDLEAAQALAQSE-----RKRHELNRQVTVQR 1461
+QL+ ++A +A + Q E +NR+VT R
Sbjct: 1942 RQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLR 1983
Score = 53.1 bits (126), Expect = 2e-06
Identities = 125/604 (20%), Positives = 236/604 (39%), Gaps = 73/604 (12%)
Query: 824 RMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKAT----------TIQKHVRG 873
++ A++ Q RA + + + RAM + +E +A T Q +
Sbjct: 1374 QLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSE 1433
Query: 874 WMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIE-ARSAEHLKRLNVG---MENKVVQ 929
W R+ +A + +A RE +AL A E + RL G ++ ++
Sbjct: 1434 WRRRQE----EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDD 1489
Query: 930 LQRKIDEQNKEFKTLSEQ-------LSVTTSTYTMEVERLKKELVHYQQSPGEDTSL-RL 981
+++Q + TL ++ L+ + VE ++ ++ SL R
Sbjct: 1490 ATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA 1549
Query: 982 QEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQI--- 1038
EE + R EL+R + + +A KD++ K V +LE+ + + L Q+
Sbjct: 1550 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 1609
Query: 1039 ---LCQSKDEFAQNSVKENLMKKELEEE--------RSRYQNLVKEYSQLEQRYDNLRDE 1087
L ++D + V +K + E + R + L K+ E D R +
Sbjct: 1610 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 1669
Query: 1088 MTII----KQTPGHRRNPSNQSSLESDSNYPSISTSEI--GDTEDALQQVEEIGLEKAAM 1141
T+ K+ G Q + ++ ++ ++VEE + +
Sbjct: 1670 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEI 1729
Query: 1142 DMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNAD-LAYNSL 1200
+ + +KR++ LE E +LQ E+ D + QA+ D D AD +A +L
Sbjct: 1730 -FSQNRESEKRLKGLEAEVLRLQ---EELAASDRARRQAQQ-----DRDEMADEVANGNL 1780
Query: 1201 KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE 1260
+ + E ++L+ L +L + + ++ Q+NS + D Y LL Q++ EL +
Sbjct: 1781 SKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLN-DRYRKLLLQVESLTTELSAERSF 1837
Query: 1261 VLILRT--QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTE 1318
+ Q + + L GR E + AR+ +H A+E+ + + E
Sbjct: 1838 SAKAESGRQQLERQIQELRGRLGEEDAGARA------RHKMTIAALESKLAQAEEQLEQE 1891
Query: 1319 DWGYLNEDGELGLAYQGLKQVA------RLLEAQLQAQSLEHEEEVEHLKAQLEALKEEM 1372
+ + A + LK+V R + QL+ Q + V+ LK QLE +EE
Sbjct: 1892 TRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEA 1951
Query: 1373 DKQQ 1376
+ Q
Sbjct: 1952 SRAQ 1955
Score = 47.8 bits (112), Expect = 1e-04
Identities = 120/610 (19%), Positives = 230/610 (37%), Gaps = 89/610 (14%)
Query: 898 KARRELKAL--RIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKT------------ 943
K R+EL+ L R++ S+E L+ V + + +L+ ++ + +E +
Sbjct: 1106 KGRQELEKLKRRLDGESSE-LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
Query: 944 --LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKI 1001
L + L + E L+ E V ++ E L EE+E+LR EL+
Sbjct: 1165 AQLLKSLREAQAALAEAQEDLESERV--ARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1222
Query: 1002 LEDAHSREKDELRKRVADLEQENALLK---DEKEQLNNQILCQSKDEFAQNSVKENLMKK 1058
++ S+ + E+ + LE+E + + E Q + Q L + ++ Q + +K
Sbjct: 1223 QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1282
Query: 1059 -------ELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNP---------- 1101
E+ E R+ +L + EQR L ++ ++ G
Sbjct: 1283 TRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1342
Query: 1102 -----SNQSSLESDSNYPSISTS-EIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE 1155
N S +++ +I S E+ TE L +E+ E+ L L RVR
Sbjct: 1343 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK----LALGSRVRA 1398
Query: 1156 LEQERKKLQVQLEK------REQQDSKKVQAEPPQTDIDLDPNAD-LAYNSLKRQELESE 1208
+E E L+ QLE+ R ++ + QA+ + + A L R+ E
Sbjct: 1399 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1458
Query: 1209 NKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQI 1268
+ L L E + V D ++ L Q + LE ++ + L +
Sbjct: 1459 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1518
Query: 1269 VSA------DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGY 1322
+A ++ R E A S E+ + + +E + + +
Sbjct: 1519 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA----L 1574
Query: 1323 LNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQT 1382
L+ ++G + L++ R+ E + L+AQ+ L++E+ +
Sbjct: 1575 LSSKDDVGKSVHELERACRVAE-----------QAANDLRAQVTELEDELTAAEDA---- 1619
Query: 1383 LLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQA 1442
+ ++E VQ + T DL+ E E+ R+L KQL+ + + +
Sbjct: 1620 -----KLRLEVTVQ---ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1671
Query: 1443 LAQSERKRHE 1452
LA + RK+ E
Sbjct: 1672 LAVAARKKLE 1681
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 540 bits (1390), Expect = e-153
Identities = 327/891 (36%), Positives = 509/891 (57%), Gaps = 27/891 (3%)
Query: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
VW+ P + KE K ++ +ED+ E+ I + + +P+ + G +
Sbjct: 10 VWLEPPSTHKTGVAIGGIIKEA-KPGKVLVEDDEGKEHWIRAEDFGVLSPMHPNSVQGVD 68
Query: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
D+ L L+E ++HNL +R+ + + IYTY G +LVA+NP++ LP+Y + + Y ++M
Sbjct: 69 DMIRLGDLNEAGMVHNLLIRY-QQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSRHM 127
Query: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETNI 192
G++ PH+FA+A Y M R++++Q I+SGESGAGKT + K +++ AT+ G S I
Sbjct: 128 GELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISGQHSW--I 185
Query: 193 EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVFQ 252
E++VL ++PI+EA GNAKT RNDNSSRFGKYI I F+ I GA + +LLEKSRV Q
Sbjct: 186 EQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKSRVCRQ 245
Query: 253 ADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQAF 312
A +ERNYHIFY + + + L+L + ++ Y + G TS EG++DA+D+ R A
Sbjct: 246 APEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAHIRSAM 305
Query: 313 TLLGVKESHQMSIFKIIASILHLGSVAIQAE--RDGDSCSISPQDVYLSNFCRLLGVEHS 370
+L +S + K++A+ILHLG+V A + D+ + + +LL V+H
Sbjct: 306 KILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAF-PTVMKLLEVQHQ 364
Query: 371 QMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSLKQ 430
++ L ++ E +++++ Q + R+A K IY LF WIV+ IN A+ T Q
Sbjct: 365 ELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAIFTPPAQ 424
Query: 431 -----HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPW 485
IG+LDI+GFE FE NSFEQ CIN+ANE LQQ F HVF +EQEEY E I W
Sbjct: 425 DPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYRSENISW 484
Query: 486 TLIDFYDNQPCIDLIEAK-LGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKPR-M 543
I + DN+P +DL+ K + I+ LLDEE + P+GTD QKL H++++ F +P+ +
Sbjct: 485 DYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAFLQPKNI 544
Query: 544 SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPATT 603
+ F I HFA +V Y ++GFLEKNRD + + + ++ +SK + ++F+ + + T
Sbjct: 545 HDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLE---LAETK 601
Query: 604 PGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDE 663
G G+ + + SNK T+G QF+ SL LM+ L P+++RCIKPN+
Sbjct: 602 LGHGTIRQAKAGNHLFKSADSNK-RPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEY 660
Query: 664 KLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKK--RELANTDK 721
K P FD + ++QLR G++ET+ I +G+P R+ + +F R+ VL+ R
Sbjct: 661 KKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKL 720
Query: 722 KAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQK 781
+ + + + ++ ++ G+TKIF R Q LE R+ A + IQK +RG+ +
Sbjct: 721 RQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYR 780
Query: 782 VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVV 841
++ R + A +TLQ + RG+ RR + + + LQ R Q + YQ +R+ V
Sbjct: 781 KEFLRQRRAAVTLQAWWRGYCNRRNFKLI--LVGFERLQAIARSQPLARQYQAMRQRTVQ 838
Query: 842 IQAFTRAMFVRRTYRQVLMEHKA-TTIQKHVRGWMARRHF-QRLRDAAIVI 890
+QA R VR +QV + +A IQ H RG ARR+F QR +A +VI
Sbjct: 839 LQALCRGYLVR---QQVQAKRRAVVVIQAHARGMAARRNFQQRKANAPLVI 886
Score = 38.9 bits (89), Expect = 0.047
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 6/82 (7%)
Query: 856 RQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKAL-----RIEA 910
R +++ A +IQK +RG+ R+ F R R AA+ +Q +R RR K + R++A
Sbjct: 759 RSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQA 818
Query: 911 -RSAEHLKRLNVGMENKVVQLQ 931
++ L R M + VQLQ
Sbjct: 819 IARSQPLARQYQAMRQRTVQLQ 840
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 513 bits (1321), Expect = e-145
Identities = 322/879 (36%), Positives = 476/879 (54%), Gaps = 87/879 (9%)
Query: 66 DILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIY 125
D ++G D+ L L+E ++NLK RF + + IYTY G V++++NPY LPIY + +
Sbjct: 12 DNMIGVGDMVLLEPLNEETFINNLKKRF-DHSEIYTYIGSVVISVNPYRSLPIYSPEKVE 70
Query: 126 TYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGG 185
Y +N ++ PHIFA+++EAY+ + +K+Q I+++GESGAGKT ++K M Y A V G
Sbjct: 71 EYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCG 130
Query: 186 SASETN-IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLL 244
+E N ++E++L S+P++EA GNAKT RNDNSSRFGKY+ I FD + +G + YLL
Sbjct: 131 KGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLL 190
Query: 245 EKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAED 304
EKSRVV Q ERN+H+FYQL + A +L L + + GVDDA +
Sbjct: 191 EKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKVNGVDDAAN 250
Query: 305 FEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAER--DGDSCSISPQDVYLSNFC 362
F R A ++G + S+ ++A++L LG++ + E +G S L C
Sbjct: 251 FRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEIC 310
Query: 363 RLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINK 422
L G++ S +E R + E T+++ Q AR+ALAK++Y++LF W+V IN+
Sbjct: 311 ELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINE 370
Query: 423 ALHTSLK-QHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKE 481
++ K + +GVLDIYGFE FE NSFEQF INY NEKLQQ F K EQEEY++E
Sbjct: 371 SIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 482 QIPWTLIDFYDNQPCIDLIEAKL-GILDLLDEECKVP-KGTDQNWAQKLYDRHSSSQHFQ 539
I WT ID+++N DLIE GIL +LDEEC P TD+ + +KL ++ QHF+
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFE 490
Query: 540 KPRMS------------NTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPL 587
RMS ++ F I H+A KV Y +GF++KN D +Y + + + L
Sbjct: 491 S-RMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHAL 549
Query: 588 VADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETL 647
+ LF + G+ +KI+++ RPP T G QF+ S+ LM+ L
Sbjct: 550 IKSLFPE------------GNPAKINLK--RPP----------TAGSQFKASVATLMKNL 585
Query: 648 NATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRY 707
P+Y+RCIKPND+K F+ Q+R G+LE +R+ AGY R AY RY
Sbjct: 586 QTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERY 645
Query: 708 RVLVKKRELANTDKKAICRSVLENLIKD----PDKFQFGRTKIFFRAGQVAY-LEKLRAD 762
++L K+ K RS +E L + +++ FGR+KIF R + + LE LR
Sbjct: 646 KMLCKQ---TWPHWKGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQ 702
Query: 763 KFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKH 822
+ +IQK RGW CR H L ++ +V+
Sbjct: 703 RLEDLATLIQKIYRGW------------------KCRTHF-------LLMKKSQIVIAAW 737
Query: 823 YRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHK----ATTIQKHVRGWMARR 878
YR ++ YQ+ + +A+VIQ++ R R+ R++ + + TTI + G ARR
Sbjct: 738 YRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARR 797
Query: 879 HFQRLRD------AAIVIQCAFRMLKARRELKALRIEAR 911
+RL++ A VI + KARRELK L+ EAR
Sbjct: 798 ELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEAR 836
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,626,408
Number of Sequences: 37866
Number of extensions: 2843528
Number of successful extensions: 24499
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 234
Number of HSP's successfully gapped in prelim test: 1194
Number of HSP's that attempted gapping in prelim test: 12916
Number of HSP's gapped (non-prelim): 6443
length of query: 1848
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1731
effective length of database: 13,817,196
effective search space: 23917566276
effective search space used: 23917566276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.