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Search of human proteins with 28882049
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]
(320 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28882049 replication factor C 2 isoform 2 [Homo sapiens] 640 0.0
gi|31563534 replication factor C 2 isoform 1 [Homo sapiens] 622 e-178
gi|6677723 replication factor C 5 isoform 1 [Homo sapiens] 171 6e-43
gi|194306571 replication factor C 5 isoform 2 [Homo sapiens] 162 3e-40
gi|194306567 replication factor C 5 isoform 2 [Homo sapiens] 162 3e-40
gi|31881687 replication factor C 4 [Homo sapiens] 151 9e-37
gi|4506491 replication factor C 4 [Homo sapiens] 151 9e-37
gi|194306569 replication factor C 5 isoform 3 [Homo sapiens] 119 5e-27
gi|108773789 replication factor C 3 isoform 2 [Homo sapiens] 58 1e-08
gi|4506489 replication factor C 3 isoform 1 [Homo sapiens] 58 1e-08
gi|18426904 Werner helicase interacting protein isoform 2 [Homo ... 49 5e-06
gi|18426902 Werner helicase interacting protein isoform 1 [Homo ... 41 0.001
gi|32528306 replication factor C large subunit [Homo sapiens] 41 0.002
gi|19718796 RAD17 homolog isoform 1 [Homo sapiens] 40 0.003
gi|19718794 RAD17 homolog isoform 1 [Homo sapiens] 40 0.003
gi|19718792 RAD17 homolog isoform 1 [Homo sapiens] 40 0.003
gi|19718784 RAD17 homolog isoform 1 [Homo sapiens] 40 0.003
gi|4506383 RAD17 homolog isoform 1 [Homo sapiens] 40 0.003
gi|19718786 RAD17 homolog isoform 2 [Homo sapiens] 40 0.003
gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo... 37 0.023
gi|5730023 RuvB-like 2 [Homo sapiens] 35 0.068
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] 34 0.20
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] 34 0.20
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 32 0.75
gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens] 32 0.98
gi|4506753 RuvB-like 1 [Homo sapiens] 32 0.98
gi|14251207 MOV10-like 1 [Homo sapiens] 32 0.98
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens] 31 1.3
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] 30 2.2
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] 30 2.2
>gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]
Length = 320
Score = 640 bits (1650), Expect = 0.0
Identities = 320/320 (100%), Positives = 320/320 (100%)
Query: 1 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60
MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
Sbjct: 1 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60
Query: 61 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDSMTDGAQQAL 120
EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDSMTDGAQQAL
Sbjct: 61 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDSMTDGAQQAL 120
Query: 121 RRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYT 180
RRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYT
Sbjct: 121 RRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYT 180
Query: 181 DDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNAN 240
DDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNAN
Sbjct: 181 DDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNAN 240
Query: 241 IDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSL 300
IDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSL
Sbjct: 241 IDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSL 300
Query: 301 LQMAGLLARLCQKTMAPVAS 320
LQMAGLLARLCQKTMAPVAS
Sbjct: 301 LQMAGLLARLCQKTMAPVAS 320
>gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]
Length = 354
Score = 622 bits (1605), Expect = e-178
Identities = 320/354 (90%), Positives = 320/354 (90%), Gaps = 34/354 (9%)
Query: 1 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60
MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
Sbjct: 1 MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL 60
Query: 61 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASND---------- 110
EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASND
Sbjct: 61 EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI 120
Query: 111 ------------------------SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 146
SMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP
Sbjct: 121 KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP 180
Query: 147 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 206
IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF
Sbjct: 181 IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF 240
Query: 207 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 266
SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF
Sbjct: 241 SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF 300
Query: 267 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 320
RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
Sbjct: 301 RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS 354
>gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]
Length = 340
Score = 171 bits (434), Expect = 6e-43
Identities = 100/316 (31%), Positives = 164/316 (51%), Gaps = 35/316 (11%)
Query: 28 PGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSIL 87
P + LPWVEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL
Sbjct: 12 PAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTIL 71
Query: 88 CLARALL-GPALKDAMLELNASN---------------------------------DSMT 113
A+ L +LELNAS+ D+MT
Sbjct: 72 ACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMT 131
Query: 114 DGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIE 173
AQ ALRR +E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+E
Sbjct: 132 QDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVE 191
Query: 174 KERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMI 233
+E+V ++DG++A++ + GDMR+ALN LQST FG + E V+ P + ++
Sbjct: 192 EEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANIL 251
Query: 234 QHCVNANIDEAYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMK 292
+N + AY+ + L L G + DI+ I +++ + ++ +
Sbjct: 252 DWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYR 311
Query: 293 IAEGVNSLLQMAGLLA 308
++ G N +Q++ L+A
Sbjct: 312 LSVGTNEKIQLSSLIA 327
>gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]
Length = 319
Score = 162 bits (411), Expect = 3e-40
Identities = 96/305 (31%), Positives = 159/305 (52%), Gaps = 35/305 (11%)
Query: 39 VEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALL-GPA 97
VEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL A+ L
Sbjct: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61
Query: 98 LKDAMLELNASN---------------------------------DSMTDGAQQALRRTM 124
+LELNAS+ D+MT AQ ALRR +
Sbjct: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI 121
Query: 125 EIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGL 184
E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+E+E+V ++DG+
Sbjct: 122 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 181
Query: 185 EAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEA 244
+A++ + GDMR+ALN LQST FG + E V+ P + ++ +N + A
Sbjct: 182 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA 241
Query: 245 YKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQM 303
Y+ + L L G + DI+ I +++ + ++ +++ G N +Q+
Sbjct: 242 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL 301
Query: 304 AGLLA 308
+ L+A
Sbjct: 302 SSLIA 306
>gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]
Length = 319
Score = 162 bits (411), Expect = 3e-40
Identities = 96/305 (31%), Positives = 159/305 (52%), Gaps = 35/305 (11%)
Query: 39 VEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALL-GPA 97
VEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL A+ L
Sbjct: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61
Query: 98 LKDAMLELNASN---------------------------------DSMTDGAQQALRRTM 124
+LELNAS+ D+MT AQ ALRR +
Sbjct: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI 121
Query: 125 EIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGL 184
E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+E+E+V ++DG+
Sbjct: 122 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 181
Query: 185 EAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEA 244
+A++ + GDMR+ALN LQST FG + E V+ P + ++ +N + A
Sbjct: 182 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA 241
Query: 245 YKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQM 303
Y+ + L L G + DI+ I +++ + ++ +++ G N +Q+
Sbjct: 242 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL 301
Query: 304 AGLLA 308
+ L+A
Sbjct: 302 SSLIA 306
>gi|31881687 replication factor C 4 [Homo sapiens]
Length = 363
Score = 151 bits (381), Expect = 9e-37
Identities = 104/334 (31%), Positives = 166/334 (49%), Gaps = 51/334 (15%)
Query: 29 GSAGHYE----LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTT 84
GS+G + +PWVEKYRP ++E+ E+ V+ L+ ++PN++ GPPGTGKT+
Sbjct: 27 GSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTS 86
Query: 85 SILCLARALLGPAL-KDAMLELNASN---------------------------------- 109
+IL AR L GP L + +LELNAS+
Sbjct: 87 TILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKI 146
Query: 110 ------DSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ 163
DSMT AQ ALRRTME SKTTRF L CN +IIEP+ SRC+ R+ L+D
Sbjct: 147 VILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKI 206
Query: 164 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE 223
RL+++ +KE V +D+G+ ++ ++GD+R+A+ LQS G E KV +
Sbjct: 207 QQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTG--GKEITEKVITD 264
Query: 224 PHPLLVKEMIQ----HCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLK 279
++ E I C + + D+ ++ L G++ ++ + V +++ K
Sbjct: 265 IAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQK 324
Query: 280 LEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQK 313
+++ +A+G + LQ+ L A + Q+
Sbjct: 325 SIITEKLAEVDKCLADGADEHLQLISLCATVMQQ 358
>gi|4506491 replication factor C 4 [Homo sapiens]
Length = 363
Score = 151 bits (381), Expect = 9e-37
Identities = 104/334 (31%), Positives = 166/334 (49%), Gaps = 51/334 (15%)
Query: 29 GSAGHYE----LPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTT 84
GS+G + +PWVEKYRP ++E+ E+ V+ L+ ++PN++ GPPGTGKT+
Sbjct: 27 GSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTS 86
Query: 85 SILCLARALLGPAL-KDAMLELNASN---------------------------------- 109
+IL AR L GP L + +LELNAS+
Sbjct: 87 TILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKI 146
Query: 110 ------DSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQ 163
DSMT AQ ALRRTME SKTTRF L CN +IIEP+ SRC+ R+ L+D
Sbjct: 147 VILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKI 206
Query: 164 ILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDE 223
RL+++ +KE V +D+G+ ++ ++GD+R+A+ LQS G E KV +
Sbjct: 207 QQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTG--GKEITEKVITD 264
Query: 224 PHPLLVKEMIQ----HCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLK 279
++ E I C + + D+ ++ L G++ ++ + V +++ K
Sbjct: 265 IAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLSDKQK 324
Query: 280 LEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQK 313
+++ +A+G + LQ+ L A + Q+
Sbjct: 325 SIITEKLAEVDKCLADGADEHLQLISLCATVMQQ 358
>gi|194306569 replication factor C 5 isoform 3 [Homo sapiens]
Length = 255
Score = 119 bits (297), Expect = 5e-27
Identities = 65/200 (32%), Positives = 110/200 (55%), Gaps = 1/200 (0%)
Query: 110 DSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLM 169
D+MT AQ ALRR +E +++ TRF L CN KII +QSRC R+ LT ++ RL
Sbjct: 43 DAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLE 102
Query: 170 NVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLV 229
+V+E+E+V ++DG++A++ + GDMR+ALN LQST FG + E V+ P +
Sbjct: 103 HVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDI 162
Query: 230 KEMIQHCVNANIDEAYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGY 288
++ +N + AY+ + L L G + DI+ I +++ + ++
Sbjct: 163 ANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMAD 222
Query: 289 THMKIAEGVNSLLQMAGLLA 308
+++ G N +Q++ L+A
Sbjct: 223 IEYRLSVGTNEKIQLSSLIA 242
>gi|108773789 replication factor C 3 isoform 2 [Homo sapiens]
Length = 305
Score = 58.2 bits (139), Expect = 1e-08
Identities = 32/77 (41%), Positives = 42/77 (54%)
Query: 99 KDAMLELNASNDSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTK 158
+D + L D +T AQ ALRRTME Y T R L CN++ K+I PI+SRC +R
Sbjct: 127 RDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPA 186
Query: 159 LTDAQILTRLMNVIEKE 175
+ I L V +KE
Sbjct: 187 PSIEDICHVLSTVCKKE 203
Score = 55.1 bits (131), Expect = 8e-08
Identities = 29/104 (27%), Positives = 57/104 (54%), Gaps = 8/104 (7%)
Query: 38 WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPA 97
WV+KYRP L + +++ ++L + G+ P++++ GP G GK T I+C+ R L G
Sbjct: 4 WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
Query: 98 LKDAMLELNASNDSMTDGAQQALRRTMEIYSKTTRFALACNASD 141
++ +L + ++T + ++ +EI + + + L N SD
Sbjct: 64 VE----KLRIEHQTITTPS----KKKIEISTIASNYHLEVNPSD 99
>gi|4506489 replication factor C 3 isoform 1 [Homo sapiens]
Length = 356
Score = 58.2 bits (139), Expect = 1e-08
Identities = 32/77 (41%), Positives = 42/77 (54%)
Query: 99 KDAMLELNASNDSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTK 158
+D + L D +T AQ ALRRTME Y T R L CN++ K+I PI+SRC +R
Sbjct: 127 RDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPA 186
Query: 159 LTDAQILTRLMNVIEKE 175
+ I L V +KE
Sbjct: 187 PSIEDICHVLSTVCKKE 203
Score = 55.1 bits (131), Expect = 8e-08
Identities = 29/104 (27%), Positives = 57/104 (54%), Gaps = 8/104 (7%)
Query: 38 WVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPA 97
WV+KYRP L + +++ ++L + G+ P++++ GP G GK T I+C+ R L G
Sbjct: 4 WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
Query: 98 LKDAMLELNASNDSMTDGAQQALRRTMEIYSKTTRFALACNASD 141
++ +L + ++T + ++ +EI + + + L N SD
Sbjct: 64 VE----KLRIEHQTITTPS----KKKIEISTIASNYHLEVNPSD 99
>gi|18426904 Werner helicase interacting protein isoform 2 [Homo
sapiens]
Length = 640
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/241 (22%), Positives = 88/241 (36%), Gaps = 52/241 (21%)
Query: 11 GEVEAQDSDPAPAFSKAPGSAGHYEL-------------PWVEKYRPVKLNEIVGNEDTV 57
G +A ++ A AF + G H P + RP L + G V
Sbjct: 187 GHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAV 246
Query: 58 SR---LEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLE-LNASNDSMT 113
+ L +P++I+ GPPG GKTT +A +++ L NA + +
Sbjct: 247 GQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIRFVTLSATNAKTNDVR 306
Query: 114 DGAQQA-------LRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILT 166
D +QA R+T+ + RF N S ++ + SRC V+ KL ++T
Sbjct: 307 DVIKQAQNEKSFFKRKTILFIDEIHRF----NKSQQVNAALLSRCRVIVLEKLPVEAMVT 362
Query: 167 RLMNVIEKERVPYTDD------------------------GLEAIIFTAQGDMRQALNNL 202
LM I + D ++ + + + GD R LN L
Sbjct: 363 ILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGL 422
Query: 203 Q 203
Q
Sbjct: 423 Q 423
>gi|18426902 Werner helicase interacting protein isoform 1 [Homo
sapiens]
Length = 665
Score = 41.2 bits (95), Expect = 0.001
Identities = 56/262 (21%), Positives = 89/262 (33%), Gaps = 69/262 (26%)
Query: 11 GEVEAQDSDPAPAFSKAPGSAGHYEL-------------PWVEKYRPVKLNEIVGNEDTV 57
G +A ++ A AF + G H P + RP L + G V
Sbjct: 187 GHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAV 246
Query: 58 SR---LEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLE-LNASNDSMT 113
+ L +P++I+ GPPG GKTT +A +++ L NA + +
Sbjct: 247 GQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIRFVTLSATNAKTNDVR 306
Query: 114 DGAQQA-------LRRTMEIYSKTTRF---------------------ALACNASDKIIE 145
D +QA R+T+ + RF A N S ++
Sbjct: 307 DVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNA 366
Query: 146 PIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDD----------------------- 182
+ SRC V+ KL ++T LM I + D
Sbjct: 367 ALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIED 426
Query: 183 -GLEAIIFTAQGDMRQALNNLQ 203
++ + + + GD R LN LQ
Sbjct: 427 KAVDTLAYLSDGDARAGLNGLQ 448
>gi|32528306 replication factor C large subunit [Homo sapiens]
Length = 1147
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/234 (21%), Positives = 84/234 (35%), Gaps = 67/234 (28%)
Query: 36 LPWVEKYRPVKLNEIVGNEDTVSRLEVFAR--------------------------EGNV 69
L WV+KY+P L I+G + S R +
Sbjct: 584 LLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSEDKKHAKFGKFSGKDDGSSF 643
Query: 70 PNIIIAGPPGTGKTT--SILCLA-------------------RALLGPALKDAMLELNAS 108
+++GPPG GKTT S++C +A++ +L + ++ S
Sbjct: 644 KAALLSGPPGVGKTTTASLVCQELGYSYVELNASDTRSKSSLKAIVAESLNNTSIKGFYS 703
Query: 109 N-----------------DSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSR- 150
N D M + + + K T+ + C +D+ I+S
Sbjct: 704 NGAASSVSTKHALIMDEVDGMAGNEDRGGIQELIGLIKHTKIPIICMCNDRNHPKIRSLV 763
Query: 151 --CAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNL 202
C LR+ + QI +M++ KE + + II A D+RQ L+NL
Sbjct: 764 HYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPPPAMNEIILGANQDIRQVLHNL 817
>gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 8/63 (12%)
Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++
Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138
Query: 89 LAR 91
L++
Sbjct: 139 LSK 141
>gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 8/63 (12%)
Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++
Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138
Query: 89 LAR 91
L++
Sbjct: 139 LSK 141
>gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 8/63 (12%)
Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++
Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138
Query: 89 LAR 91
L++
Sbjct: 139 LSK 141
>gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 8/63 (12%)
Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++
Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138
Query: 89 LAR 91
L++
Sbjct: 139 LSK 141
>gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 8/63 (12%)
Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++
Sbjct: 79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 138
Query: 89 LAR 91
L++
Sbjct: 139 LSK 141
>gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]
Length = 681
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/63 (28%), Positives = 35/63 (55%), Gaps = 8/63 (12%)
Query: 37 PWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPN--------IIIAGPPGTGKTTSILC 88
PWV+KY+P +E+ ++ + +E + + + ++I GPPG GKTT++
Sbjct: 90 PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTLKI 149
Query: 89 LAR 91
L++
Sbjct: 150 LSK 152
>gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo
sapiens]
Length = 479
Score = 37.0 bits (84), Expect = 0.023
Identities = 21/55 (38%), Positives = 30/55 (54%)
Query: 68 NVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDSMTDGAQQALRR 122
NVP I+I GPP +GKTT + L + L L L LN + + T+ + L+R
Sbjct: 56 NVPRIVILGPPASGKTTIAMWLCKHLNSSLLTLENLILNEFSYTATEARRLYLQR 110
>gi|5730023 RuvB-like 2 [Homo sapiens]
Length = 463
Score = 35.4 bits (80), Expect = 0.068
Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 6/70 (8%)
Query: 65 REGNVPN--IIIAGPPGTGKTTSILCLARALLGPALKDAML---ELNASNDSMTDGAQQA 119
REG + ++IAG PGTGKT + +A+A LGP + E+ + S T+ QA
Sbjct: 64 REGKIAGRAVLIAGQPGTGKTAIAMGMAQA-LGPDTPFTAIAGSEIFSLEMSKTEALTQA 122
Query: 120 LRRTMEIYSK 129
RR++ + K
Sbjct: 123 FRRSIGVRIK 132
>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
Length = 750
Score = 33.9 bits (76), Expect = 0.20
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 45 VKLNEIVGNEDTVSRL----------EVFAREGNVP--NIIIAGPPGTGKTTSILCLARA 92
VK ++ GN+ T+ + EV+ G VP +++ GPPG GKT +A
Sbjct: 156 VKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGE 215
Query: 93 LLGPALKDAMLELNASNDSMTDGAQQALRRTME 125
L P LK A E+ + ++ ++Q LR E
Sbjct: 216 LDLPILKVAAPEIVS---GVSGESEQKLRELFE 245
>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
Length = 856
Score = 33.9 bits (76), Expect = 0.20
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 45 VKLNEIVGNEDTVSRL----------EVFAREGNVP--NIIIAGPPGTGKTTSILCLARA 92
VK ++ GN+ T+ + EV+ G VP +++ GPPG GKT +A
Sbjct: 262 VKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGE 321
Query: 93 LLGPALKDAMLELNASNDSMTDGAQQALRRTME 125
L P LK A E+ + ++ ++Q LR E
Sbjct: 322 LDLPILKVAAPEIVS---GVSGESEQKLRELFE 351
>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
Length = 1844
Score = 32.0 bits (71), Expect = 0.75
Identities = 11/36 (30%), Positives = 23/36 (63%)
Query: 31 AGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFARE 66
+G ++ W EKY+P +E++GNE + +L + ++
Sbjct: 1047 SGTEDMLWTEKYQPQTASELIGNELAIKKLHSWLKD 1082
>gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]
Length = 1118
Score = 31.6 bits (70), Expect = 0.98
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
Query: 70 PNIIIAGPPGTGKT----TSILCLARALLGPALKDAMLELNASNDSMTDGAQQALRRTME 125
P +I GPPGTGKT T + LAR GP L A N + D +T+ Q + +
Sbjct: 486 PLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCA--PSNIAVDQLTEKIHQTGLKVVR 543
Query: 126 IYSKT 130
+ +K+
Sbjct: 544 LCAKS 548
>gi|4506753 RuvB-like 1 [Homo sapiens]
Length = 456
Score = 31.6 bits (70), Expect = 0.98
Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 72 IIIAGPPGTGKTTSILCLARALLG--PALKDAMLELNASNDSMTDGAQQALRRTMEIYSK 129
+++AGPPGTGKT L +A+ L P E+ ++ T+ + RR + + K
Sbjct: 66 VLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIK 125
Query: 130 TTR 132
T+
Sbjct: 126 ETK 128
>gi|14251207 MOV10-like 1 [Homo sapiens]
Length = 1211
Score = 31.6 bits (70), Expect = 0.98
Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 38 WVEKYRPVK------LNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLAR 91
WV++ + K N ++ ++ + + + I+ GPPGTGKT +I+ A
Sbjct: 726 WVDEIQTPKARKMEFFNPVLNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTII-EAV 784
Query: 92 ALLGPALKDAMLELNASNDSMTDGAQQALRRTMEIYSKT-TRFALACNASDKIIEPIQSR 150
+ AL D+ + + A ++S D L + + T R C + +I+ ++
Sbjct: 785 LQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCRFEEIVIDAVKPY 844
Query: 151 C 151
C
Sbjct: 845 C 845
>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
Length = 403
Score = 31.2 bits (69), Expect = 1.3
Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 11/69 (15%)
Query: 28 PGSAGHYELPWV-EKYRPVKLNEIVGNEDTVSRLEVFAREGNVP--NIIIAGPPGTGKTT 84
PG+ + E+ + E+ R +L E++ E ++ E+F R G +P ++ GPPGTGKT
Sbjct: 141 PGNVSYSEIGGLSEQIR--ELREVI--ELPLTNPELFQRVGIIPPKGCLLYGPPGTGKT- 195
Query: 85 SILCLARAL 93
LARA+
Sbjct: 196 ---LLARAV 201
>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
Length = 753
Score = 30.4 bits (67), Expect = 2.2
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 72 IIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDSMT-DGAQQALRRTMEIYSK 129
+++AGPPG GKT + +AR L + L S T + ++ +R E+ S+
Sbjct: 237 VLLAGPPGVGKTQLVRAVAREAGAELLAVSAPALQGSRPGETEENVRRVFQRARELASR 295
>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
Length = 773
Score = 30.4 bits (67), Expect = 2.2
Identities = 17/32 (53%), Positives = 21/32 (65%), Gaps = 5/32 (15%)
Query: 67 GNVPN-IIIAGPPGTGKTTSILCLARALLGPA 97
G +P I++ GPPGTGKT LARA+ G A
Sbjct: 369 GKLPKGILLVGPPGTGKT----LLARAVAGEA 396
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,890,746
Number of Sequences: 37866
Number of extensions: 501146
Number of successful extensions: 1594
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1527
Number of HSP's gapped (non-prelim): 81
length of query: 320
length of database: 18,247,518
effective HSP length: 102
effective length of query: 218
effective length of database: 14,385,186
effective search space: 3135970548
effective search space used: 3135970548
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.