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Search of human proteins with 28372543
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28372543 protein disulfide isomerase-like, testis expressed
[Homo sapiens]
(584 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28372543 protein disulfide isomerase-like, testis expressed [... 1145 0.0
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 278 1e-74
gi|94966757 protein disulfide isomerase A2 [Homo sapiens] 253 3e-67
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 133 4e-31
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 117 4e-26
gi|22748703 endoplasmic reticulum protein 27 kDa [Homo sapiens] 112 9e-25
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 54 3e-07
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 54 5e-07
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul... 52 2e-06
gi|54633317 thioredoxin domain containing 11 [Homo sapiens] 48 3e-05
gi|5803121 protein disulfide isomerase A5 [Homo sapiens] 47 6e-05
gi|110349719 titin isoform N2-A [Homo sapiens] 44 3e-04
gi|21361403 thioredoxin 2 precursor [Homo sapiens] 40 0.008
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 39 0.010
gi|227430327 calsequestrin 1 [Homo sapiens] 39 0.010
gi|5031973 protein disulfide isomerase A6 [Homo sapiens] 38 0.023
gi|50592994 thioredoxin [Homo sapiens] 37 0.050
gi|110611228 utrophin [Homo sapiens] 36 0.086
gi|16579828 zinc finger protein 91 [Homo sapiens] 35 0.15
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 34 0.33
gi|66932943 variable charge, X chromosome [Homo sapiens] 34 0.33
gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens] 34 0.43
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 34 0.43
gi|38505222 thioredoxin domain containing 10 [Homo sapiens] 34 0.43
gi|221219020 NYD-SP11 protein [Homo sapiens] 33 0.56
gi|4506467 radixin [Homo sapiens] 33 0.56
gi|55770834 centromere protein F [Homo sapiens] 33 0.56
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 33 0.73
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 33 0.73
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 33 0.73
>gi|28372543 protein disulfide isomerase-like, testis expressed
[Homo sapiens]
Length = 584
Score = 1145 bits (2961), Expect = 0.0
Identities = 584/584 (100%), Positives = 584/584 (100%)
Query: 1 MDLLWMPLLLVAACVSAVHSSPEVNAGVSSIHITKPVHILEERSLLVLTPAGLTQMLNQT 60
MDLLWMPLLLVAACVSAVHSSPEVNAGVSSIHITKPVHILEERSLLVLTPAGLTQMLNQT
Sbjct: 1 MDLLWMPLLLVAACVSAVHSSPEVNAGVSSIHITKPVHILEERSLLVLTPAGLTQMLNQT 60
Query: 61 RFLMVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITIEKELQQEFGITKAPE 120
RFLMVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITIEKELQQEFGITKAPE
Sbjct: 61 RFLMVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITIEKELQQEFGITKAPE 120
Query: 121 LKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQVAEFVISRPLVIVGFF 180
LKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQVAEFVISRPLVIVGFF
Sbjct: 121 LKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQVAEFVISRPLVIVGFF 180
Query: 181 QDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLDSVLVFKKGKIVNRQKLINDS 240
QDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLDSVLVFKKGKIVNRQKLINDS
Sbjct: 181 QDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLDSVLVFKKGKIVNRQKLINDS 240
Query: 241 TNKQELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLLFVSKSSESYGIIIQHYKLAS 300
TNKQELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLLFVSKSSESYGIIIQHYKLAS
Sbjct: 241 TNKQELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLLFVSKSSESYGIIIQHYKLAS 300
Query: 301 KEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILNLSSDARYKMPSDDITYESLK 360
KEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILNLSSDARYKMPSDDITYESLK
Sbjct: 301 KEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILNLSSDARYKMPSDDITYESLK 360
Query: 361 KFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKC 420
KFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKC
Sbjct: 361 KFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKC 420
Query: 421 KMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLMYLDRYPFFRLFPSGSQQAVLYKGEH 480
KMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLMYLDRYPFFRLFPSGSQQAVLYKGEH
Sbjct: 421 KMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLMYLDRYPFFRLFPSGSQQAVLYKGEH 480
Query: 481 TLKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELEN 540
TLKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELEN
Sbjct: 481 TLKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELEN 540
Query: 541 MTKYVSKLEEPAGKKKTSEEVVVVVAKPKGPPVQKKKPKVKEEL 584
MTKYVSKLEEPAGKKKTSEEVVVVVAKPKGPPVQKKKPKVKEEL
Sbjct: 541 MTKYVSKLEEPAGKKKTSEEVVVVVAKPKGPPVQKKKPKVKEEL 584
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 278 bits (711), Expect = 1e-74
Identities = 156/485 (32%), Positives = 262/485 (54%), Gaps = 4/485 (0%)
Query: 41 EERSLLVLTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGFGK 100
EE +LVL + + L ++L+V F+ P + LA E KA + + I K
Sbjct: 22 EEDHVLVLRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAK 81
Query: 101 VDITIEKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFN 160
VD T E +L Q++G+ P +K F G+ + P E+ +V WL+++ A
Sbjct: 82 VDATEESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLP 141
Query: 161 SSEQVAEFVISRPLVIVGFFQDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLD 220
V S + ++GFF+D+E + A+ F + ++ FG+ + +V ++ + D
Sbjct: 142 DGAAAESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKD 201
Query: 221 SVLVFKKGKIVNRQKLINDSTNKQELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLL 280
V++FKK + K+ L IK + VIE+ + I I +H+LL
Sbjct: 202 GVVLFKK--FDEGRNNFEGEVTKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILL 259
Query: 281 FVSKSSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILN 340
F+ KS Y + ++K A++ F+ KILFI +D+D N R+ ++F + + + P+V+++
Sbjct: 260 FLPKSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLIT 319
Query: 341 LSSD-ARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNFNV 399
L + +YK S+++T E + +F FL H S+E+P+ WD+ VK LVGKNF
Sbjct: 320 LEEEMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFED 379
Query: 400 VVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLMYLDR 459
V FD++K+VFV FYAPW CK L P+ ++LG Y++H I+IAK+D TAN+++ + +
Sbjct: 380 VAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHS 439
Query: 460 YPFFRLFPSGSQQAVL-YKGEHTLKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLA 518
+P + FP+ + + V+ Y GE TL GF FLES + D+D+L +E+ E + E
Sbjct: 440 FPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDMEEDD 499
Query: 519 EEKEV 523
++K V
Sbjct: 500 DQKAV 504
>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
Length = 525
Score = 253 bits (646), Expect = 3e-67
Identities = 148/457 (32%), Positives = 244/457 (53%), Gaps = 5/457 (1%)
Query: 39 ILEERSLLVLTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGF 98
I +E +LVL+ L L + L+V F+ P + LA E KA ++ +
Sbjct: 38 IPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTL 97
Query: 99 GKVDITIEKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFL 158
KVD ++EL +EFG+T+ P LK F GNR+ P G ++ + WLRR++ A
Sbjct: 98 AKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMR 157
Query: 159 FNSSEQVAEFVISRPLVIVGFFQDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVT 218
+ R LV++GFFQDL++E F + +D ++TFG+ + +F +T
Sbjct: 158 LEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALDMTFGLTDRPRLFQQFGLT 217
Query: 219 LDSVLVFKKGKIVNRQKLINDSTNKQ--ELNRVIKQHLTDFVIEYNTENKDLISELHIMS 276
D+V++FKK +++ +L+R + H V E+N++ I I++
Sbjct: 218 KDTVVLFKKFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILN 277
Query: 277 HMLLFVSKSSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSV 336
H+LLFV+++ ++ ++ + A+ F+ ++LF++VD N V +YF + P++
Sbjct: 278 HLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVAAD-NEHVLQYFGLKAEAAPTL 336
Query: 337 QILNLSSDARYK-MPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGK 395
+++NL + +Y + +T S+ F + L+ + S+EIP WDQ VK LVGK
Sbjct: 337 RLVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGK 396
Query: 396 NFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLM 455
NF V FD+ K+VFV FYAPW CK + P E L KYQ+H IIIA++D TAN++
Sbjct: 397 NFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAF 456
Query: 456 YLDRYPFFRLFPSGSQQAVL-YKGEHTLKGFSDFLES 491
+ +P + FP+G + V+ YK L+ FS FL++
Sbjct: 457 AVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDN 493
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 133 bits (335), Expect = 4e-31
Identities = 117/475 (24%), Positives = 214/475 (45%), Gaps = 26/475 (5%)
Query: 46 LVLTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITI 105
LVLT +++N ++V F+ P + LA E KA + + K I KVD T
Sbjct: 180 LVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATA 239
Query: 106 EKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQV 165
E +L + F ++ P LK+F +G P G E +V ++ Q + + +QV
Sbjct: 240 ETDLAKRFDVSGYPTLKIFRKGR---PYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQV 296
Query: 166 AEFVISRP-LVIVGFFQDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRF-HVTLDSVL 223
EF+ ++I+G F+ + + + D + E T I +F V+ ++
Sbjct: 297 QEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAKFLKVSQGQLV 356
Query: 224 VFKKGKIVNRQKLINDSTNKQELNRVIKQHLTDFVIEYNTE---NKDLISELHIMSHMLL 280
V + K ++ + + + Q + + DFV++Y ++ + ++ + L
Sbjct: 357 VMQPEKFQSKYEPRSHMMDVQGSTQ--DSAIKDFVLKYALPLVGHRKVSNDAKRYTRRPL 414
Query: 281 FVSKSSESYGIIIQHYKLASKEFQNKILFILVD--------ADEPRNGRVFKYFRVTEVD 332
V S + Y+ A++ +++K+L + D ADE K ++E
Sbjct: 415 VVVYYSVDFSF---DYRAATQFWRSKVLEVAKDFPEYTFAIADEEDYAGEVKDLGLSESG 471
Query: 333 IPSVQILNLSSDARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQL 392
+ S ++ M ++ ++L++F +F S+ +PK ++G VK +
Sbjct: 472 EDVNAAILDESGKKFAMEPEEFDSDTLREFVTAFKKGKLKPVIKSQPVPKN-NKGPVKVV 530
Query: 393 VGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTANDI 452
VGK F+ +V D +KDV + FYAPW CK L P+ L +KY+ ++IAK+D TAND+
Sbjct: 531 VGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDV 590
Query: 453 --QLMYLDRYPFFRLFPSGSQQ--AVLYKGEHTLKGFSDFLESHIKTKIEDEDEL 503
++ +P PSG ++ G+ L+ S F+E H ++EL
Sbjct: 591 PSDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRDLEHLSKFIEEHATKLSRTKEEL 645
Score = 47.0 bits (110), Expect = 5e-05
Identities = 51/188 (27%), Positives = 80/188 (42%), Gaps = 29/188 (15%)
Query: 396 NFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHS-TIIIAKIDVTANDIQL 454
NF+ V DK+ V + FYAPW CK P E++ ++ I +AKID T+ +
Sbjct: 71 NFDNFVADKDT-VLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLA 129
Query: 455 MYLD--RYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIED----------EDE 502
D YP ++ G QAV Y+G T + I K+ + E
Sbjct: 130 SRFDVSGYPTIKILKKG--QAVDYEGSRT--------QEEIVAKVREVSQPDWTPPPEVT 179
Query: 503 LLSVEQN--EVIEE-EVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKTSE 559
L+ ++N EV+ + +++ E P G ++ +PE E K +SK P K
Sbjct: 180 LVLTKENFDEVVNDADIILVEFYAPWC--GHCKKLAPEYEKAAKELSKRSPPIPLAKVDA 237
Query: 560 EVVVVVAK 567
+AK
Sbjct: 238 TAETDLAK 245
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 117 bits (292), Expect = 4e-26
Identities = 106/450 (23%), Positives = 192/450 (42%), Gaps = 38/450 (8%)
Query: 63 LMVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITIEKELQQEFGITKAPELK 122
++V F P + LA E A + K + KVD T ++G++ P LK
Sbjct: 48 MLVEFFAPWCGHCKRLAPEYEAAATRL---KGIVPLAKVDCTANTNTCNKYGVSGYPTLK 104
Query: 123 LFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQVAEFVISRPLVIVGFFQD 182
+F +G E + G + +V L++Q + + E+ +F+ + IVGFF D
Sbjct: 105 IFRDGE--EAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDD 162
Query: 183 LEEEVAELFYDVIKDFPE-LTFGVITIGNVIGRFHVTLDSVLVFKKGKIVNR--QKLIND 239
E F + + F + +++ + + +++F+ + N+ K +
Sbjct: 163 SFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAY 222
Query: 240 STNKQ---ELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLLFVSKSSESYGIIIQHY 296
+ K ++ + I++++ +NKDLI ++ Y + +
Sbjct: 223 TEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAY----------YDVDYEKN 272
Query: 297 KLASKEFQNKILFI---LVDADEPRNGRV-----FKY------FRVTEVDIPSVQILNLS 342
S ++N+++ + +DA N V F + T +IP V I
Sbjct: 273 AKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAK 332
Query: 343 SDARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNFNVVVF 402
+ ++L++F + + N ++ SE IP+ D G VK +V +NF+ +V
Sbjct: 333 GEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESND-GPVKVVVAENFDEIVN 391
Query: 403 DKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLMYLDR-YP 461
++ KDV + FYAPW CK L P +ELG K I+IAK+D TAND+ Y R +P
Sbjct: 392 NENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFP 451
Query: 462 FFRLFPSGSQ-QAVLYKGEHTLKGFSDFLE 490
P+ + Y+G L F +L+
Sbjct: 452 TIYFSPANKKLNPKKYEGGRELSDFISYLQ 481
>gi|22748703 endoplasmic reticulum protein 27 kDa [Homo sapiens]
Length = 273
Score = 112 bits (280), Expect = 9e-25
Identities = 64/217 (29%), Positives = 116/217 (53%), Gaps = 6/217 (2%)
Query: 167 EFVISRPLVIVGFFQDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLDSVLVFK 226
EF+ + + ++GFFQDLE + + +++ FP ++FG+ T V+ +++T +++ +F+
Sbjct: 51 EFIAATEVAVIGFFQDLEIPAVPILHSMVQKFPGVSFGISTDSEVLTHYNITGNTICLFR 110
Query: 227 KGKIVNRQKLIND----STNKQELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLLFV 282
+ N Q + D S + +L+R I+ + V EYN + I H+LL +
Sbjct: 111 L--VDNEQLNLEDEDIESIDATKLSRFIEINSLHMVTEYNPVTVIGLFNSVIQIHLLLIM 168
Query: 283 SKSSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQILNLS 342
+K+S Y + Y+ A+K FQ KILFILVD+ NG+V +F++ E +P++ I
Sbjct: 169 NKASPEYEENMHRYQKAAKLFQGKILFILVDSGMKENGKVISFFKLKESQLPALAIYQTL 228
Query: 343 SDARYKMPSDDITYESLKKFGRSFLSKNATKHQSSEE 379
D +P+ +++ E ++ F FLS K E
Sbjct: 229 DDEWDTLPTAEVSVEHVQNFCDGFLSGKLLKENRESE 265
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 54.3 bits (129), Expect = 3e-07
Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 19/135 (14%)
Query: 409 FVMFYAPWSKKCKMLFPLLEELGRKYQN--HSTIIIAKIDVTAND--IQLMYLDRYPFFR 464
FVMF+APW C+ L P +LG KY + + + +AK+D TA+ + YP +
Sbjct: 81 FVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLK 140
Query: 465 LFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVP 524
LF G Q+AV Y+G + E+ +L E + E E P
Sbjct: 141 LFKPG-QEAVKYQGPRDFQTL--------------ENWMLQTLNEEPVTPEPEVEPPSAP 185
Query: 525 MMRKGLPEQQSPELE 539
+++GL E + E
Sbjct: 186 ELKQGLYELSASNFE 200
Score = 53.5 bits (127), Expect = 5e-07
Identities = 49/196 (25%), Positives = 93/196 (47%), Gaps = 14/196 (7%)
Query: 334 PSVQILNLSSDA-RYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWD--QGLVK 390
P++++ +A +Y+ P D +++L+ + L++ + E P + QGL
Sbjct: 137 PTLKLFKPGQEAVKYQGPRD---FQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLY- 192
Query: 391 QLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTAN 450
+L NF + V + D F+ F+APW CK L P E+L ++ T+ I K+D T +
Sbjct: 193 ELSASNFELHV--AQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQH 250
Query: 451 DIQLM---YLDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIEDEDELLSVE 507
+L + YP F G ++ YKG+ L+ +++ES ++ E ++
Sbjct: 251 -YELCSGNQVRGYPTLLWFRDG-KKVDQYKGKRDLESLREYVESQLQRTETGATETVTPS 308
Query: 508 QNEVIEEEVLAEEKEV 523
+ V+ E A++ V
Sbjct: 309 EAPVLAAEPEADKGTV 324
Score = 50.8 bits (120), Expect = 3e-06
Identities = 48/152 (31%), Positives = 71/152 (46%), Gaps = 14/152 (9%)
Query: 357 ESLKKFGRSFLSKN---ATKHQSSEEIPKYW-----DQGLVKQLVGKNFNVVVFDKEKDV 408
ESL+++ S L + AT+ + E P D+G V L NF+ + E
Sbjct: 284 ESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTI--AEGIT 341
Query: 409 FVMFYAPWSKKCKMLFPLLEELGRK-YQNHSTIIIAKIDVTA-NDIQLMYLDR-YPFFRL 465
F+ FYAPW CK L P EEL +K + + + IA++D TA +I Y R YP L
Sbjct: 342 FIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLL 401
Query: 466 FPSGSQQAVLYKGEHTLKGFSDFLESHIKTKI 497
F G ++ + G L F+ S K ++
Sbjct: 402 F-RGGKKVSEHSGGRDLDSLHRFVLSQAKDEL 432
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 53.5 bits (127), Expect = 5e-07
Identities = 49/196 (25%), Positives = 93/196 (47%), Gaps = 14/196 (7%)
Query: 334 PSVQILNLSSDA-RYKMPSDDITYESLKKFGRSFLSKNATKHQSSEEIPKYWD--QGLVK 390
P++++ +A +Y+ P D +++L+ + L++ + E P + QGL
Sbjct: 29 PTLKLFKPGQEAVKYQGPRD---FQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLY- 84
Query: 391 QLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTAN 450
+L NF + V + D F+ F+APW CK L P E+L ++ T+ I K+D T +
Sbjct: 85 ELSASNFELHV--AQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQH 142
Query: 451 DIQLM---YLDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIEDEDELLSVE 507
+L + YP F G ++ YKG+ L+ +++ES ++ E ++
Sbjct: 143 -YELCSGNQVRGYPTLLWFRDG-KKVDQYKGKRDLESLREYVESQLQRTETGATETVTPS 200
Query: 508 QNEVIEEEVLAEEKEV 523
+ V+ E A++ V
Sbjct: 201 EAPVLAAEPEADKGTV 216
Score = 50.8 bits (120), Expect = 3e-06
Identities = 48/152 (31%), Positives = 71/152 (46%), Gaps = 14/152 (9%)
Query: 357 ESLKKFGRSFLSKN---ATKHQSSEEIPKYW-----DQGLVKQLVGKNFNVVVFDKEKDV 408
ESL+++ S L + AT+ + E P D+G V L NF+ + E
Sbjct: 176 ESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTI--AEGIT 233
Query: 409 FVMFYAPWSKKCKMLFPLLEELGRK-YQNHSTIIIAKIDVTA-NDIQLMYLDR-YPFFRL 465
F+ FYAPW CK L P EEL +K + + + IA++D TA +I Y R YP L
Sbjct: 234 FIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLL 293
Query: 466 FPSGSQQAVLYKGEHTLKGFSDFLESHIKTKI 497
F G ++ + G L F+ S K ++
Sbjct: 294 F-RGGKKVSEHSGGRDLDSLHRFVLSQAKDEL 324
>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
[Homo sapiens]
Length = 406
Score = 52.0 bits (123), Expect = 2e-06
Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 6/103 (5%)
Query: 410 VMFYAPWSKKCKMLFPLLEE----LGRKYQNHSTIIIAKIDVTAN-DIQLMY-LDRYPFF 463
V FYA W + +ML P+ EE + ++ N + ++ A++D + DI Y + +YP
Sbjct: 51 VNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTL 110
Query: 464 RLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIEDEDELLSV 506
+LF +G Y+G+ ++K +D++ I++ +L +
Sbjct: 111 KLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEI 153
Score = 42.7 bits (99), Expect = 0.001
Identities = 59/294 (20%), Positives = 114/294 (38%), Gaps = 7/294 (2%)
Query: 48 LTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLA---EELGKAVEIMGKGKNGIGFGKVDIT 104
L + ++LN +V F+ + S+ L EE ++ +N + F +VD
Sbjct: 34 LDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCD 93
Query: 105 IEKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQ 164
++ Q + I+K P LKLF G + +G AL ++R+Q S +
Sbjct: 94 QHSDIAQRYRISKYPTLKLFRNGMMMKR-EYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152
Query: 165 VAEFVISRPLVIVGFFQDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLDSVLV 224
+ S+ I+G+F+ + + +F V + + G+V + D+++
Sbjct: 153 ITTLDRSK-RNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIY 211
Query: 225 FKKGKIVNRQKLINDSTNKQELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLLFVSK 284
G + TN I+ V E EN + ++E + +L + +
Sbjct: 212 KPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKE 271
Query: 285 SSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQI 338
+ES I + I F+ D D+ R+ + + + T D P + I
Sbjct: 272 DTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLL--HIQKTPADCPVIAI 323
>gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
Length = 958
Score = 47.8 bits (112), Expect = 3e-05
Identities = 36/134 (26%), Positives = 65/134 (48%), Gaps = 6/134 (4%)
Query: 338 ILNLSSDARYKM-PSDDITYESLKKFGRSF--LSKNATKHQSSEEIPKYWDQGLVKQLVG 394
I+++ ++ Y + P + +L+ F ++F L +H ++ Q L+ ++
Sbjct: 611 IVDVKEESHYILDPKQALMKLTLESFIQNFSVLYSPLKRHLIGSGSAQFPSQHLITEVTT 670
Query: 395 KNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQL 454
F VV K+ DV +++YAPW C L + +L R T +A+IDV+ ND+
Sbjct: 671 DTFWEVVLQKQ-DVLLLYYAPWCGFCPSLNHIFIQLARNLP-MDTFTVARIDVSQNDLPW 728
Query: 455 MYL-DRYPFFRLFP 467
++ DR P FP
Sbjct: 729 EFMVDRLPTVLFFP 742
>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
Length = 519
Score = 46.6 bits (109), Expect = 6e-05
Identities = 37/130 (28%), Positives = 57/130 (43%), Gaps = 10/130 (7%)
Query: 386 QGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKI 445
Q V LVG NF + K+K VMFYAPW CK + P +++ I A +
Sbjct: 396 QTSVLHLVGDNFRETL-KKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAV 454
Query: 446 DVTAND----IQLMYLDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIEDED 501
D + Q + YP F + G + A Y + T GF+++ I+ E +
Sbjct: 455 DCVKDKNQDLCQQEAVKGYPTFHYYHYG-KFAEKYDSDRTELGFTNY----IRALREGDH 509
Query: 502 ELLSVEQNEV 511
E L ++ E+
Sbjct: 510 ERLGKKKEEL 519
Score = 43.9 bits (102), Expect = 4e-04
Identities = 41/197 (20%), Positives = 91/197 (46%), Gaps = 10/197 (5%)
Query: 258 VIEYNTENKDLISELHIMSHMLLFVSKSSESYGIIIQHYKLASKEFQNKILFILVDADEP 317
+IE ++ KDL L +++L+ SKS + ++ ++ + + VD +
Sbjct: 29 LIERISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTVAQAVKGQGTICWVDCGDA 88
Query: 318 RNGRVFKYFRVT-EVDIPSVQILNLSSDARYKMPSDDITYESLKKFGRSFLSKNATKHQS 376
+ ++ K +V V++ + A + + +T++S+ F K+
Sbjct: 89 ESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVAF-----LKDPKGPPL 143
Query: 377 SEEIPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQN 436
EE P D +V K+F ++ +EK + +MFYAPW CK + P ++ + +
Sbjct: 144 WEEDPGAKD--VVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRG 201
Query: 437 HSTIIIAKIDVTANDIQ 453
H+ ++A ++V +++ +
Sbjct: 202 HA--VLAGMNVYSSEFE 216
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 5/100 (5%)
Query: 379 EIPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNH- 437
E P + G V L ++F+ V + V VMF+APW CK + P E+
Sbjct: 268 ETPWADEGGSVYHLTDEDFDQFV-KEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEA 326
Query: 438 -STIIIAKIDVTAND--IQLMYLDRYPFFRLFPSGSQQAV 474
S+ ++A +D T N + ++ +P + F +G + AV
Sbjct: 327 DSSGVLAAVDATVNKALAERFHISEFPTLKYFKNGEKYAV 366
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 41 EERSLLVLTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLAEELGKAVEIM-GKGKNGIGFG 99
E S+ LT Q + + ++V+FH P + + E KA E + G+ +
Sbjct: 274 EGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLA 333
Query: 100 KVDITIEKELQQEFGITKAPELKLFFEGNR 129
VD T+ K L + F I++ P LK F G +
Sbjct: 334 AVDATVNKALAERFHISEFPTLKYFKNGEK 363
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 44.3 bits (103), Expect = 3e-04
Identities = 33/110 (30%), Positives = 57/110 (51%), Gaps = 12/110 (10%)
Query: 485 FSDFLESHIKTK-IEDEDELLSVEQNEVIEEEVL----AEEKEVPMMRKGLPEQQSPELE 539
F + + +H++ +E+E+E + E+ + EEEV+ + EVP RK +PE++ P
Sbjct: 9910 FEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVP--RKPVPEEKKPVPV 9967
Query: 540 NMTKYVSKLEEPAGKKKTSEEVVVVVAKPKGPPVQK-----KKPKVKEEL 584
K + P KK E+V V++ K + PP K KKP +E++
Sbjct: 9968 PKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKV 10017
Score = 38.9 bits (89), Expect = 0.013
Identities = 34/110 (30%), Positives = 54/110 (49%), Gaps = 22/110 (20%)
Query: 496 KIEDEDELLSVEQNEVIEEEVLA---------------EEKEVPMMRKGLPEQQS--PEL 538
+I E+E+L E+ + EEE + EE+EVP + +PE++ PE
Sbjct: 10112 EIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEE 10171
Query: 539 ENMTKYVSKLEEPAG----KKKTSEEVVVVVAKPKGPPVQ-KKKPKVKEE 583
E + + K+ PA KKK +E+ VV+ K + PP + + PK EE
Sbjct: 10172 EVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEE 10221
Score = 38.5 bits (88), Expect = 0.017
Identities = 38/102 (37%), Positives = 54/102 (52%), Gaps = 12/102 (11%)
Query: 493 IKTKIEDEDELLSVEQNEVIEEEVLAEEKEV-PMMRKGLPEQQS--PELENM---TKYVS 546
+ + E+E+L E+ V EEEVL EE+EV P + LPE++ PE E + + V
Sbjct: 10097 VPVALPQEEEVL-FEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVP 10155
Query: 547 KLEE--PAGKKKTSEEVVVVVAKPKGP---PVQKKKPKVKEE 583
EE P ++ EE V+ KPK P PV + K KV E+
Sbjct: 10156 PEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEK 10197
Score = 36.2 bits (82), Expect = 0.086
Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 13/75 (17%)
Query: 507 EQNEVIEEEVLA--EEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKTSEEVVVV 564
E E+ EE +A EEK VP+ + PE P + EEP KK E+ V V
Sbjct: 10806 EPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVP---------EEP--KKIIPEKKVPV 10854
Query: 565 VAKPKGPPVQKKKPK 579
+ KP+ PP ++ +P+
Sbjct: 10855 IKKPEAPPPKEPEPE 10869
Score = 35.4 bits (80), Expect = 0.15
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 493 IKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPA 552
+ K+E++ +L E+ EV+ EV E +E P+ + +PE + P +E + +
Sbjct: 10215 VPKKVEEKRIILPKEE-EVLPVEVTEEPEEEPISEEEIPE-EPPSIEEVEEVAPPRVPEV 10272
Query: 553 GKKKTSEEVVVVVAKPKGPP--VQKKKPKVK 581
KK E V K + PP V KK P+ K
Sbjct: 10273 IKKAVPEAPTPVPKKVEAPPAKVSKKIPEEK 10303
Score = 35.0 bits (79), Expect = 0.19
Identities = 31/111 (27%), Positives = 46/111 (41%), Gaps = 17/111 (15%)
Query: 490 ESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRK-------------GLPEQQSP 536
E + + E+E E+ EV E EV+ E +E + K + E+Q
Sbjct: 9501 EEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEK 9560
Query: 537 ELENMTKYVSKLEEPAGKKKTSEEVVVVVAKPKGPPVQKKK----PKVKEE 583
++ K +K+EEP K +V K PV KK+ PKV EE
Sbjct: 9561 KIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEE 9611
Score = 34.3 bits (77), Expect = 0.33
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 10/92 (10%)
Query: 500 EDELLSVEQNEVIEEEVLAEEKEVPMMR--------KGLPEQQSPELENMTKYVSKLEEP 551
E+E +SV++ E EE + KE + E++ E +Y+++ E+P
Sbjct: 9733 EEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKP 9792
Query: 552 AGKKKTSEEVVVVVAKPKGPPVQKKKPKVKEE 583
K EE V KPK PP + K V EE
Sbjct: 9793 IPVKPVPEEPVPT--KPKAPPAKVLKKAVPEE 9822
Score = 32.7 bits (73), Expect = 0.95
Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 496 KIEDEDELLSVEQNEVIEEEV---LAEEKEVPMMRKGLPEQQSPEL-ENMTKYVSKLEEP 551
++ +E E ++ E+ EEE +AEE+E + +PE+ + E + K E P
Sbjct: 10802 EVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAP 10861
Query: 552 AGKKKTSEEVV---VVVAKPKGPPVQKKKPKVKEEL 584
K+ E+V+ + +P PP K VKE++
Sbjct: 10862 PPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKI 10897
Score = 31.2 bits (69), Expect = 2.8
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 4/84 (4%)
Query: 498 EDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKT 557
E+E +SV + E EEE AE E +M E + +E +SK E + T
Sbjct: 9500 EEEGVSISVYREEEREEEEEAEVTEYEVME----EPEEYVVEEKLHIISKRVEAEPAEVT 9555
Query: 558 SEEVVVVVAKPKGPPVQKKKPKVK 581
+ +V KPK P ++ P K
Sbjct: 9556 ERQEKKIVLKPKIPAKIEEPPPAK 9579
Score = 30.8 bits (68), Expect = 3.6
Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 13/96 (13%)
Query: 490 ESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLE 549
E H K+ E+ E+ EV E+ A K + K +P ++ P TK V + E
Sbjct: 10411 EEHRVEKVHRVIEVFEAEEVEVFEKPK-APPKGPEISEKIIPPKKPP-----TKVVPRKE 10464
Query: 550 EPA-----GKKKTSEEVVVVVAKPKGPPVQKKKPKV 580
PA KK EE V V +P+ PP K P+V
Sbjct: 10465 PPAKVPEVPKKIVVEEKVRVPEEPRVPPT--KVPEV 10498
Score = 30.4 bits (67), Expect = 4.7
Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 13/106 (12%)
Query: 488 FLESHIKTKIEDEDELLSVEQNEVIEEE----VLAEEKEVPMMRKGLPEQQSPELENMTK 543
F SH + E+ + Q E++ EE +++ E P LPE+ +PE
Sbjct: 9248 FFASHTE---EEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVP 9304
Query: 544 YVSKLEEPA------GKKKTSEEVVVVVAKPKGPPVQKKKPKVKEE 583
K+E PA KK EE V K P K P+V ++
Sbjct: 9305 IPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKK 9350
>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
Length = 166
Score = 39.7 bits (91), Expect = 0.008
Identities = 20/54 (37%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 394 GKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDV 447
G +F V + E V V F+A W CK+L P LE++ K H +++AK+D+
Sbjct: 67 GPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKMVAK--QHGKVVMAKVDI 118
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 39.3 bits (90), Expect = 0.010
Identities = 34/125 (27%), Positives = 59/125 (47%), Gaps = 22/125 (17%)
Query: 374 HQSSEEIPKYWDQGL---VKQLVGKNFNVVVFD-KEKDVFVM-FYAPWSKKCKMLFPLLE 428
H S+E+I ++ + + V L FN +V K +V+++ FY+PW C++L P +
Sbjct: 540 HHSAEQILEFIEDLMNPSVVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWK 599
Query: 429 ELGRKYQNHSTIIIAKIDVTANDIQLMY-------LDRYPFFRLFPSGSQQAVLYKGEHT 481
+ R + I+V + D Q + + RYP R FP S +A Y H+
Sbjct: 600 RMAR-------TLTGLINVGSIDCQQYHSFCAQENVQRYPEIRFFPPKSNKAYHY---HS 649
Query: 482 LKGFS 486
G++
Sbjct: 650 YNGWN 654
>gi|227430327 calsequestrin 1 [Homo sapiens]
Length = 396
Score = 39.3 bits (90), Expect = 0.010
Identities = 40/198 (20%), Positives = 83/198 (41%), Gaps = 12/198 (6%)
Query: 63 LMVLFHNP----SSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITIEKELQQEFGITKA 118
L +L+H P + Q + EEL + G+GFG VD + + ++ G+T+
Sbjct: 67 LALLYHEPPEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEV 126
Query: 119 PELKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQVAEFV-ISRPLVIV 177
+ +F E I G + +V +L + L ++ F I + ++
Sbjct: 127 DSMYVF---KGDEVIEYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEIKLI 183
Query: 178 GFFQDLEEEVAELFYDVIKDF-PELTFGVITIGNVIGRFHVTLDSVLVFKKGKIVNRQKL 236
G+F+ + E + F D ++F P + F V + + L+ + ++ +
Sbjct: 184 GYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYE--AFMEEPVT 241
Query: 237 INDSTN-KQELNRVIKQH 253
I D N ++E+ +++H
Sbjct: 242 IPDKPNSEEEIVNFVEEH 259
>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
Length = 440
Score = 38.1 bits (87), Expect = 0.023
Identities = 29/97 (29%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
Query: 389 VKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGR--KYQNHSTIIIAKID 446
V +L +F+ V D E V FYAPW CK L P K Q + +A +D
Sbjct: 162 VIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVD 221
Query: 447 VTANDI--QLMYLDRYPFFRLFPSGSQQAVLYKGEHT 481
T N + + +P ++F G + V Y G T
Sbjct: 222 ATVNQVLASRYGIRGFPTIKIFQKG-ESPVDYDGGRT 257
Score = 35.4 bits (80), Expect = 0.15
Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 14/118 (11%)
Query: 389 VKQLVGKNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVT 448
V +L NFN V + V FYAPW C+ L P +++ +T + + V
Sbjct: 27 VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTP-------EWKKAATALKDVVKVG 79
Query: 449 ANDIQLMY-------LDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIED 499
A D + + +P ++F S + Y+G T + D S ++ ++D
Sbjct: 80 AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKD 137
Score = 33.5 bits (75), Expect = 0.56
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 64 MVLFHNPSSKQSRNLAEELGKAV-EIMGKGKNGIGFGKVDITIEKELQQEFGITKAPELK 122
MV F+ P +NL E A E+ + K + VD T+ + L +GI P +K
Sbjct: 182 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIK 241
Query: 123 LFFEG 127
+F +G
Sbjct: 242 IFQKG 246
Score = 30.0 bits (66), Expect = 6.1
Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 5/102 (4%)
Query: 45 LLVLTPAGLTQMLNQTRFL-MVLFHNPSSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDI 103
++ LTP+ + + Q+ L +V F+ P + L E KA + K+ + G VD
Sbjct: 27 VIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATAL---KDVVKVGAVDA 83
Query: 104 TIEKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALV 145
L ++G+ P +K+ F N++ P +G A+V
Sbjct: 84 DKHHSLGGQYGVQGFPTIKI-FGSNKNRPEDYQGGRTGEAIV 124
>gi|50592994 thioredoxin [Homo sapiens]
Length = 105
Score = 37.0 bits (84), Expect = 0.050
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 10/84 (11%)
Query: 388 LVKQLVGKNFNVVVFDKEKD--VFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKI 445
+VKQ+ K D D V V F A W CKM+ P L KY N +I ++
Sbjct: 1 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSN---VIFLEV 57
Query: 446 DV-----TANDIQLMYLDRYPFFR 464
DV A++ ++ + + FF+
Sbjct: 58 DVDDCQDVASECEVKCMPTFQFFK 81
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 36.2 bits (82), Expect = 0.086
Identities = 37/149 (24%), Positives = 70/149 (46%), Gaps = 11/149 (7%)
Query: 378 EEIPKYWDQGLVKQLVGK--NFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQ 435
E+ P + +VK+LV + + N+ V + ++ A S +++ P L EL R ++
Sbjct: 1679 EKKPTSKQEEIVKRLVSELDDANLQVENVRDQALILMNARGSSSRELVEPKLAELNRNFE 1738
Query: 436 NHSTII-IAKIDVTANDIQLMYLDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIK 494
S I AK+ + + + F +G + L K E+ ++ F+E H++
Sbjct: 1739 KVSQHIKSAKLLIAQEPLYQCLVTT----ETFETGVPFSDLEKLENDIENMLKFVEKHLE 1794
Query: 495 TKIEDEDELLSVEQNEVIEEEVLAEEKEV 523
+ DEDE + E ++ EEVL +E+
Sbjct: 1795 S--SDEDEKMDEESAQI--EEVLQRGEEM 1819
>gi|16579828 zinc finger protein 91 [Homo sapiens]
Length = 570
Score = 35.4 bits (80), Expect = 0.15
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Query: 504 LSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMT----KYVSKLEEPAGKKKTSE 559
+S E+ E EEE+L E+E+P E P LE T + K++E KK+
Sbjct: 205 ISSEEEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKV 264
Query: 560 EVVVVVAKPKGPPVQKKKPKVK 581
EV V V + + + ++P K
Sbjct: 265 EVEVEVKEEENEIREDEEPPRK 286
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 34.3 bits (77), Expect = 0.33
Identities = 23/90 (25%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Query: 494 KTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAG 553
+TK++ ED+ E+ E ++EV +E + P+ ++ P+++ + E + K + K E+
Sbjct: 641 ETKVKPEDKK---EEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKE-VKKEIKKEEKKEP 696
Query: 554 KKKTSEEVVVVVAKPKGPPVQKKKPKVKEE 583
KK+ +E K + +KK+ K +E+
Sbjct: 697 KKEVKKETPPKEVKKEVKKEEKKEVKKEEK 726
Score = 32.7 bits (73), Expect = 0.95
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Query: 498 EDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKT 557
E ++E V + +E+ E KE M++K P + + K V EEP+ K
Sbjct: 560 ESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAE 619
Query: 558 SEEVVVVVAKPKGPPVQ--KKKPKVKEE 583
E KPK + KK+ KVK E
Sbjct: 620 VAEKQATDVKPKAAKEKTVKKETKVKPE 647
Score = 30.0 bits (66), Expect = 6.1
Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 470 SQQAVLYKGEHTLKGFS--DFLESHIKTKIEDEDELLSVEQNEVIE-EEVLAEEKEVPMM 526
S++ V+ K + +K + E + +K E V + + + + A+EK V
Sbjct: 582 SKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKE 641
Query: 527 RKGLPEQQSPELENMTKYVSKLEEPAGKKKTSEEVVVVVAKPKGPPVQKK-KPKVKEE 583
K PE + E E K V+K E+ KK KPK V+K+ K ++K+E
Sbjct: 642 TKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEE--------KPKKEEVKKEVKKEIKKE 691
Score = 29.6 bits (65), Expect = 8.0
Identities = 26/103 (25%), Positives = 55/103 (53%), Gaps = 9/103 (8%)
Query: 489 LESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPEL------ENMT 542
+ES K ++ + + + + V E+EV ++E+ P+ + + E+Q+ ++ E
Sbjct: 580 VESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAE-VAEKQATDVKPKAAKEKTV 638
Query: 543 KYVSKLEEPAGKKKTSEEVVVVVAKPKGP-PVQKKKPKVKEEL 584
K +K++ P KK+ E+ VAK + P++K++ KEE+
Sbjct: 639 KKETKVK-PEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEV 680
>gi|66932943 variable charge, X chromosome [Homo sapiens]
Length = 206
Score = 34.3 bits (77), Expect = 0.33
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 490 ESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEV--PMMRKGLPEQ---QSPELENMTKY 544
E+ ++ + E E+ E EE L++E EV P+ ++ E+ Q E+E
Sbjct: 107 EAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQ 166
Query: 545 VSKLEEPAGKKKTSEEVVVVVAKPKGPPVQKKK 577
S++EEP ++ EE + ++ + PP Q+ +
Sbjct: 167 ESQVEEPLSQESEMEEPLSQESQVEEPPSQESE 199
Score = 32.3 bits (72), Expect = 1.2
Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
Query: 490 ESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEV--PMMRKGLPEQ---QSPELENMTKY 544
ES ++ + E E+ E EE L++E EV P+ ++ E+ Q E+E
Sbjct: 127 ESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQ 186
Query: 545 VSKLEEPAGKKKTSEEV 561
S++EEP ++ EE+
Sbjct: 187 ESQVEEPPSQESEMEEL 203
>gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]
Length = 506
Score = 33.9 bits (76), Expect = 0.43
Identities = 31/82 (37%), Positives = 38/82 (46%), Gaps = 10/82 (12%)
Query: 507 EQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVS--KLEEPAGKKKTSEEVVVV 564
E+N EV AEEKEVP K +PE + E E + K + K EE A K E V
Sbjct: 193 EENPKENPEVKAEEKEVP---KEIPEVKDEEKE-VPKEIPEVKAEEKADSKDCMEATPEV 248
Query: 565 VAKPKGPPV----QKKKPKVKE 582
PK P K++PK E
Sbjct: 249 KEDPKEVPQVKADDKEQPKATE 270
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 33.9 bits (76), Expect = 0.43
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 505 SVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKTSEE---- 560
S+E E +EE +++E K E+Q +LEN + + LEE KK+ +E
Sbjct: 229 SLEDEETKKEEETPKQEEQKESEKMKSEEQPMDLENRST-ANVLEETTVKKEKEDEKELV 287
Query: 561 -VVVVVAKPKGPPVQKKKPKVKEE 583
+ V+V K P ++K +KEE
Sbjct: 288 KLPVIVKLEKPLPENEEKKIIKEE 311
>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
Length = 454
Score = 33.9 bits (76), Expect = 0.43
Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 403 DKEKDVFVM-FYAPWSKKCKMLFPLLEELGRKYQN-HSTIIIAKIDVTA 449
++ D++++ FYAPW CK L P+ E+G + ++ S + + K+D T+
Sbjct: 38 NRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATS 86
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 33.5 bits (75), Expect = 0.56
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 13/100 (13%)
Query: 490 ESHIKTKIE------DEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTK 543
E H ++E ++ E LS E+ E EEE EE+EV + E++ E E K
Sbjct: 2223 EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEV----REEEEERKEEEEGEEK 2278
Query: 544 YVSKLEEPAGKKKTSEEVVVVVAKPKGPPVQKKKPKVKEE 583
V K EE KKK ++ V K + V ++K ++ E
Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEE---VFEEKEEIMSE 2315
Score = 30.4 bits (67), Expect = 4.7
Identities = 32/138 (23%), Positives = 65/138 (47%), Gaps = 8/138 (5%)
Query: 447 VTANDIQLMYLDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIEDEDELLSV 506
V + +L+ ++R P ++ + + GE T K + + E K +++E++L
Sbjct: 1441 VVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGE-TRKSWKAWKEEWEKRLLQEEEKLHQA 1499
Query: 507 EQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKK-TSEEVVVVV 565
+ EEE+L E+K++ E+ ENM SK ++ +++ T EE V
Sbjct: 1500 GEKLSPEEEMLQEDKKLKW------EEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSRE 1553
Query: 566 AKPKGPPVQKKKPKVKEE 583
+ K V +++ ++EE
Sbjct: 1554 GEEKEQQVTEEQRHIQEE 1571
Score = 30.0 bits (66), Expect = 6.1
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 482 LKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENM 541
++ D LE E+E+E E+ E EEEV EE+E +G E++ E E
Sbjct: 2230 MESLLDELEKQESLSSEEEEEREEEEERE--EEEVREEEEERKEEEEG--EEKQVEKEEE 2285
Query: 542 TKYVSKLEEPAGKKKTSEEV 561
K K E+ + + EEV
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEV 2305
Score = 29.6 bits (65), Expect = 8.0
Identities = 21/95 (22%), Positives = 48/95 (50%), Gaps = 2/95 (2%)
Query: 491 SHIKTKIEDEDELLSVEQNEVIE--EEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKL 548
S +TK+ E+ELL E+ ++ + E++ EE+ + R+ L E++ + ++++ +
Sbjct: 1764 SEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSM 1823
Query: 549 EEPAGKKKTSEEVVVVVAKPKGPPVQKKKPKVKEE 583
EE K + + + K +K+K ++E
Sbjct: 1824 EELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKE 1858
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 33.5 bits (75), Expect = 0.56
Identities = 52/234 (22%), Positives = 87/234 (37%), Gaps = 46/234 (19%)
Query: 395 KNFNVVVFDKEKDVFVMFYAPWSKKCKMLFPLL---EELGRKYQNHSTIIIAKIDVTAND 451
K F + DK+ FV FYAP + K + L EL + + TI + ++ A +
Sbjct: 253 KKFVIKPIDKKAPDFV-FYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQARE 311
Query: 452 ------IQLMYLDRYPFFRLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIE------- 498
++ L+ R ++ + + E ++ E IK + E
Sbjct: 312 EKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRK 371
Query: 499 ----DEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLP------EQQSPELENMTKYVSKL 548
D++ + E+ E +E+E A E+ + K EQ + EL T ++ L
Sbjct: 372 ALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALL 431
Query: 549 EEPAGKK-------------------KTSEEVVVVVAKPKGPPVQKKKPKVKEE 583
EE KK KT EE+ V++ P PP P + E
Sbjct: 432 EEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIPPTENE 485
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 33.5 bits (75), Expect = 0.56
Identities = 36/189 (19%), Positives = 84/189 (44%), Gaps = 7/189 (3%)
Query: 357 ESLKKFGRSFLSKNATKHQSSEEIPKYWDQGLVKQLVGKNFNVVVFDKEKDVFVMFYAPW 416
+SL+ ++ + K + E+ K ++ +++ +F ++ +KE++ V
Sbjct: 2378 QSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEK-VQMKEKS 2436
Query: 417 SKKCKMLFPLLEELGRKY---QNHSTIIIAKIDVTANDIQLMYLDRYPFFRLFPSGSQQA 473
S +ML L+EL + N AK ++ ++ + L++ +
Sbjct: 2437 STAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNY 2496
Query: 474 VLYKGEHTLKGFSDFLESHIKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQ 533
++ + ++ G +E K K+E +DE +S +N++ ++E L + L ++
Sbjct: 2497 IVLQS--SVNGLIQEVEDG-KQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKE 2553
Query: 534 QSPELENMT 542
Q+ EL N+T
Sbjct: 2554 QNLELRNLT 2562
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 33.1 bits (74), Expect = 0.73
Identities = 19/88 (21%), Positives = 47/88 (53%), Gaps = 7/88 (7%)
Query: 496 KIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKK 555
KI +++E + ++ ++ E+E + +E+E M G E++ E E M + K+ E K
Sbjct: 524 KIREQEEKIREQEEKIREQEEMMQEQEEKM---GEQEEKMQEQEKMRRQEEKIREQEEKI 580
Query: 556 KTSEEVVVVVAKPKGPPVQKKKPKVKEE 583
+ +E + + + + +++ K++E+
Sbjct: 581 REQKEKI----REQEEKIWEQEEKIREQ 604
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 33.1 bits (74), Expect = 0.73
Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Query: 493 IKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPA 552
+K K+E LL Q ++EE+ +E+E+ K + +Q+ E M + +L E
Sbjct: 251 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE----EKMWRQEERLREQE 306
Query: 553 GKKKTSEE 560
GK + EE
Sbjct: 307 GKMREQEE 314
Score = 29.6 bits (65), Expect = 8.0
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 498 EDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSP--ELENMTKYVSKLEEPAGKK 555
E+E+ + E+ +EE + E++E ++ LPEQ+ E E M + K+ E K
Sbjct: 461 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520
Query: 556 KTSEEV 561
+ EE+
Sbjct: 521 RDQEEM 526
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 33.1 bits (74), Expect = 0.73
Identities = 20/68 (29%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Query: 493 IKTKIEDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSPELENMTKYVSKLEEPA 552
+K K+E LL Q ++EE+ +E+E+ K + +Q+ E M + +L E
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQE----EKMWRQEERLREQE 268
Query: 553 GKKKTSEE 560
GK + EE
Sbjct: 269 GKMREQEE 276
Score = 29.6 bits (65), Expect = 8.0
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 498 EDEDELLSVEQNEVIEEEVLAEEKEVPMMRKGLPEQQSP--ELENMTKYVSKLEEPAGKK 555
E+E+ + E+ +EE + E++E ++ LPEQ+ E E M + K+ E K
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462
Query: 556 KTSEEV 561
+ EE+
Sbjct: 463 RDQEEM 468
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,873,167
Number of Sequences: 37866
Number of extensions: 935314
Number of successful extensions: 4025
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 3732
Number of HSP's gapped (non-prelim): 310
length of query: 584
length of database: 18,247,518
effective HSP length: 108
effective length of query: 476
effective length of database: 14,157,990
effective search space: 6739203240
effective search space used: 6739203240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.