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Search of human proteins with 27894337
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27894337 keratin 20 [Homo sapiens]
(424 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27894337 keratin 20 [Homo sapiens] 816 0.0
gi|4557701 keratin 17 [Homo sapiens] 398 e-111
gi|15431310 keratin 14 [Homo sapiens] 394 e-109
gi|24234699 keratin 19 [Homo sapiens] 379 e-105
gi|24430190 keratin 15 [Homo sapiens] 367 e-101
gi|24430192 keratin 16 [Homo sapiens] 367 e-101
gi|131412228 keratin 13 isoform b [Homo sapiens] 362 e-100
gi|131412225 keratin 13 isoform a [Homo sapiens] 362 e-100
gi|4557699 keratin 12 [Homo sapiens] 360 1e-99
gi|192807292 keratin 24 [Homo sapiens] 348 4e-96
gi|4504927 keratin 36 [Homo sapiens] 342 4e-94
gi|94538345 keratin 35 [Homo sapiens] 333 1e-91
gi|153945736 keratin 27 [Homo sapiens] 329 3e-90
gi|195972866 keratin 10 [Homo sapiens] 326 2e-89
gi|114431246 keratin 25D [Homo sapiens] 320 2e-87
gi|116488398 keratin 32 [Homo sapiens] 313 2e-85
gi|14917117 keratin 33A [Homo sapiens] 313 2e-85
gi|27894339 keratin 23 [Homo sapiens] 312 3e-85
gi|14917115 keratin 31 [Homo sapiens] 312 4e-85
gi|14917119 keratin 34 [Homo sapiens] 311 9e-85
gi|10337581 type I hair keratin 3B [Homo sapiens] 310 1e-84
gi|40354195 keratin 18 [Homo sapiens] 308 5e-84
gi|4557888 keratin 18 [Homo sapiens] 308 5e-84
gi|31559829 keratin 25 [Homo sapiens] 304 9e-83
gi|125490370 type I hair keratin KA36 [Homo sapiens] 294 1e-79
gi|31559815 keratin 26 [Homo sapiens] 290 1e-78
gi|55956899 keratin 9 [Homo sapiens] 287 1e-77
gi|15431318 keratin 38 [Homo sapiens] 278 7e-75
gi|55770882 keratin 37 [Homo sapiens] 278 9e-75
gi|148277620 type I hair keratin KA35 [Homo sapiens] 273 2e-73
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 816 bits (2107), Expect = 0.0
Identities = 424/424 (100%), Positives = 424/424 (100%)
Query: 1 MDFSRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDLT 60
MDFSRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDLT
Sbjct: 1 MDFSRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDLT 60
Query: 61 GGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAY 120
GGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAY
Sbjct: 61 GGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAY 120
Query: 121 YRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVF 180
YRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVF
Sbjct: 121 YRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVF 180
Query: 181 DDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMN 240
DDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMN
Sbjct: 181 DDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMN 240
Query: 241 EMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIEL 300
EMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIEL
Sbjct: 241 EMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIEL 300
Query: 301 QSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIK 360
QSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIK
Sbjct: 301 QSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIK 360
Query: 361 TRLEQEIATYRRLLEGEDVKTTEYQLSTLEERDIKKTRKIKTVVQEVVDGKVVSSEVKEV 420
TRLEQEIATYRRLLEGEDVKTTEYQLSTLEERDIKKTRKIKTVVQEVVDGKVVSSEVKEV
Sbjct: 361 TRLEQEIATYRRLLEGEDVKTTEYQLSTLEERDIKKTRKIKTVVQEVVDGKVVSSEVKEV 420
Query: 421 EENI 424
EENI
Sbjct: 421 EENI 424
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 398 bits (1023), Expect = e-111
Identities = 208/395 (52%), Positives = 281/395 (71%), Gaps = 14/395 (3%)
Query: 29 LGTTPSVYGGAGGRGIRISNSRHTV--------NYGSDLTGGGDLFVGNEKMAMQNLNDR 80
LG G AGG G + S ++ YGS G L G EK MQNLNDR
Sbjct: 35 LGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDR 94
Query: 81 LASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNAR 140
LASYL+KVR LE++N++LEV+I+ WY+ AP RDYS YYR IEEL+++I A + NA
Sbjct: 95 LASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNAN 154
Query: 141 CVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKD 200
+LQIDNA+LAA+DFR K+ETE+ +RL+VEAD+ GL +V D+LTL + DLE+QIE L ++
Sbjct: 155 ILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEE 214
Query: 201 LALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQ 260
LA LKK H+EE++ L +G +NVE+DAAPG++L I+NEMR +YE MA+KN ++A++
Sbjct: 215 LAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDW 274
Query: 261 FERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKAR 320
F +T L ++V N+E ++ + +++ELRRT Q+LEIELQS LSMK SLE L ET+ R
Sbjct: 275 FFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENR 334
Query: 321 YSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVK 380
Y QL+ +Q L+ S+E QL Q+R ME+QN EY ILLD+KTRLEQEIATYRRLLEGED
Sbjct: 335 YCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAH 394
Query: 381 TTEYQLSTLEERDIKKTRKIKTVVQEVVDGKVVSS 415
T+Y +++ TR+++T+V+EV DGKV+SS
Sbjct: 395 LTQY------KKEPVTTRQVRTIVEEVQDGKVISS 423
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 394 bits (1011), Expect = e-109
Identities = 204/383 (53%), Positives = 280/383 (73%), Gaps = 10/383 (2%)
Query: 36 YGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSN 95
YGG G G+ +G GG L VG+EK+ MQNLNDRLASYL+KVR LE++N
Sbjct: 88 YGGGLGAGLG-------GGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEAN 140
Query: 96 SKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDF 155
+ LEV+I+ WY+ P +DYS Y++ IE+LR++I A + NA +LQIDNA+LAA+DF
Sbjct: 141 ADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDF 200
Query: 156 RLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGL 215
R KYETE +R++VEAD+ GL +V D+LTL + DLE+QIE L ++LA LKK H+EE++ L
Sbjct: 201 RTKYETELNLRMSVEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNAL 260
Query: 216 HKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVN 275
+G VNVE+DAAPG++L I+NEMR +YE MA+KN ++A+E F +T L ++V N
Sbjct: 261 RGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATN 320
Query: 276 TEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSL 335
+E ++ + +++ELRRT Q+LEIELQS LSMK SLE++LEETK RY QLA +Q ++ S+
Sbjct: 321 SELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSV 380
Query: 336 EAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGED--VKTTEYQLSTLEERD 393
E QL Q+R ME+QN EY ILLD+KTRLEQEIATYRRLLEGED + ++++ + RD
Sbjct: 381 EEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSSGSQSSRD 440
Query: 394 I-KKTRKIKTVVQEVVDGKVVSS 415
+ +R+I+T V +V DGKVVS+
Sbjct: 441 VTSSSRQIRTKVMDVHDGKVVST 463
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 379 bits (974), Expect = e-105
Identities = 190/355 (53%), Positives = 266/355 (74%), Gaps = 9/355 (2%)
Query: 33 PSVYGGAGGRGIRISNSRHTVN---------YGSDLTGGGDLFVGNEKMAMQNLNDRLAS 83
PS++GG+GGRG+ +S++R + YG LT L GNEK+ MQNLNDRLAS
Sbjct: 34 PSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLAS 93
Query: 84 YLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNARCVL 143
YL+KVR LE +N +LEV+I+ WY+ P RDYS YY I++LR +I A ++N+R VL
Sbjct: 94 YLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRIVL 153
Query: 144 QIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLAL 203
QIDNA+LAA+DFR K+ETE+ +R++VEAD+ GL +V D+LTL +TDLE+QIE L ++LA
Sbjct: 154 QIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAY 213
Query: 204 LKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFER 263
LKK H+EE+ L +G V+VEVD+APG +L I+++MR +YEVMA++N ++A+ F
Sbjct: 214 LKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTS 273
Query: 264 QTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSS 323
+T L ++V +TE+L+ + ++T+LRRT Q LEIELQS LSMK +LE TL ET+AR+ +
Sbjct: 274 RTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGA 333
Query: 324 QLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGED 378
QLA++Q+L+S +EAQL +R++ ERQN EY L+DIK+RLEQEIATYR LLEG++
Sbjct: 334 QLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 367 bits (942), Expect = e-101
Identities = 197/393 (50%), Positives = 265/393 (67%), Gaps = 9/393 (2%)
Query: 30 GTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGG-GDLFVGNEKMAMQNLNDRLASYLEKV 88
G SV+GG G G+ +G GG G L GNEK+ MQNLNDRLASYL+KV
Sbjct: 71 GGAGSVFGGGFGGGVG-------GGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKV 123
Query: 89 RTLEQSNSKLEVQIKQWYETNAPRAGR-DYSAYYRQIEELRSQIKDAQLQNARCVLQIDN 147
R LE++N+ LEV+I WY+ P + DYS Y++ IEELR +I + N+R +L+IDN
Sbjct: 124 RALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDN 183
Query: 148 AKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKE 207
A+LAA+DFRLKYE E +R VEAD+ GL +V D+LTL +TDLE+QIE LN++LA LKK
Sbjct: 184 ARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKN 243
Query: 208 HQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAV 267
H+EE+ L VNVE+DAAPG++L ++ EMR++YE MA+KN ++ + F +T
Sbjct: 244 HEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEE 303
Query: 268 LQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLAN 327
L ++V NTE ++ ++ ++T+LRRT Q LEIELQS LSMK LE++L ET+ RY++QL
Sbjct: 304 LNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQ 363
Query: 328 LQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQLS 387
+Q L+ LEAQL ++R ME QN EY +LLDIKTRLEQEIATYR LLEG+D K +
Sbjct: 364 IQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGIGIR 423
Query: 388 TLEERDIKKTRKIKTVVQEVVDGKVVSSEVKEV 420
+ V+E VDG+VVSS +E+
Sbjct: 424 EASSGGGGSSSNFHINVEESVDGQVVSSHKREI 456
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 367 bits (942), Expect = e-101
Identities = 191/352 (54%), Positives = 253/352 (71%), Gaps = 3/352 (0%)
Query: 36 YGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSN 95
YGG G G +G GG L VG+EK+ MQNLNDRLASYL+KVR LE++N
Sbjct: 86 YGGGLGAGF---GGGLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEAN 142
Query: 96 SKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDF 155
+ LEV+I+ WY+ P +DYS Y++ IE+LR++I A ++NA+ +LQIDNA+LAA+DF
Sbjct: 143 ADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDF 202
Query: 156 RLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGL 215
R KYE E +R TVEAD+ GL +V D+LTL +TDLE+QIE L ++LA L+K H+EE+ L
Sbjct: 203 RTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLAL 262
Query: 216 HKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVN 275
G VNVE+DAAPG++L I+NEMR +YE MA+KN ++A+ F +T L ++V N
Sbjct: 263 RGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASN 322
Query: 276 TEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSL 335
+E ++ + ++TELRR Q LEIELQS LSMK SLE++LEETK RY QL+ +Q L+ S+
Sbjct: 323 SELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSV 382
Query: 336 EAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQLS 387
E QL Q+R ME+Q+ EY ILLD+KTRLEQEIATYRRLLEGED + Q S
Sbjct: 383 EEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQAS 434
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 362 bits (929), Expect = e-100
Identities = 188/346 (54%), Positives = 255/346 (73%), Gaps = 4/346 (1%)
Query: 36 YGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSN 95
YGG G G + V++G+ G L GNEK+ MQNLNDRLASYLEKVR LE++N
Sbjct: 73 YGGGLGGGFGGGFAGGFVDFGAC---DGGLLTGNEKITMQNLNDRLASYLEKVRALEEAN 129
Query: 96 SKLEVQIKQWYETNAPRAG-RDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAED 154
+ LEV+I+ W+ +P + RDYS YY+ IEELR +I A ++N R +L+IDNA+LAA+D
Sbjct: 130 ADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADD 189
Query: 155 FRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDG 214
FRLKYE E +R +VEAD+ GL +V D+LTL KTDLE+QIE LN++LA +KK H+EE+
Sbjct: 190 FRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKE 249
Query: 215 LHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTV 274
+ VNVE+DA PG++L ++ EMR++YE MA++N ++A+E F ++A L ++V+
Sbjct: 250 FSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVST 309
Query: 275 NTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSS 334
NT ++ ++ ++TELRRT Q LEIELQS LSMK LE+T+ ET+ RY+ QL +Q L+SS
Sbjct: 310 NTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISS 369
Query: 335 LEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVK 380
+EAQL ++RS ME QN EY +LLDIKTRLEQEIATYR LLEG+D K
Sbjct: 370 IEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 362 bits (929), Expect = e-100
Identities = 188/346 (54%), Positives = 255/346 (73%), Gaps = 4/346 (1%)
Query: 36 YGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSN 95
YGG G G + V++G+ G L GNEK+ MQNLNDRLASYLEKVR LE++N
Sbjct: 73 YGGGLGGGFGGGFAGGFVDFGAC---DGGLLTGNEKITMQNLNDRLASYLEKVRALEEAN 129
Query: 96 SKLEVQIKQWYETNAPRAG-RDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAED 154
+ LEV+I+ W+ +P + RDYS YY+ IEELR +I A ++N R +L+IDNA+LAA+D
Sbjct: 130 ADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADD 189
Query: 155 FRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDG 214
FRLKYE E +R +VEAD+ GL +V D+LTL KTDLE+QIE LN++LA +KK H+EE+
Sbjct: 190 FRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKE 249
Query: 215 LHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTV 274
+ VNVE+DA PG++L ++ EMR++YE MA++N ++A+E F ++A L ++V+
Sbjct: 250 FSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVST 309
Query: 275 NTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSS 334
NT ++ ++ ++TELRRT Q LEIELQS LSMK LE+T+ ET+ RY+ QL +Q L+SS
Sbjct: 310 NTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISS 369
Query: 335 LEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVK 380
+EAQL ++RS ME QN EY +LLDIKTRLEQEIATYR LLEG+D K
Sbjct: 370 IEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 360 bits (925), Expect = 1e-99
Identities = 194/401 (48%), Positives = 281/401 (70%), Gaps = 15/401 (3%)
Query: 37 GGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNS 96
G GG G+ S + G G L G+EK MQNLNDRLASYL+KVR LE++N+
Sbjct: 92 GSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANT 151
Query: 97 KLEVQIKQWYETN----APRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAA 152
+LE +I++WYET A + DYS YY IE+LR++I A + NA+ +LQIDNA+LAA
Sbjct: 152 ELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAA 211
Query: 153 EDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEV 212
EDFR+KYE E +R VEAD+ GL +V D+LTL +TDLE+QIE LN++LA +KK H++E+
Sbjct: 212 EDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDEL 271
Query: 213 DGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQV 272
V+VE+DAAPG++L ++N+MR +YE +A++N ++A+ F ++ L++++
Sbjct: 272 QSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEI 331
Query: 273 TVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLL 332
+ NTE+L+ ++ ++T+LRR Q+LEIELQS L+MK+SLE +L E + Y +QL+ +Q L+
Sbjct: 332 STNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLI 391
Query: 333 SSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGED-----------VKT 381
S+LEAQL+Q+R++ ERQN ++ LL++K RLE EI TYRRLL+GE +
Sbjct: 392 SNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDS 451
Query: 382 TEYQLSTLEERDIKKTRKIKTVVQEVVDGKVVSSEVKEVEE 422
ST +D KTRKIKTVVQE+V+G+VVSS+V+E+EE
Sbjct: 452 KSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEIEE 492
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 348 bits (894), Expect = 4e-96
Identities = 192/401 (47%), Positives = 270/401 (67%), Gaps = 32/401 (7%)
Query: 54 NYGSDLTGG---GDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNA 110
+YG + GG G LF G EK MQNLNDRLA+YL+KVR LE++N+ LE +IK+WY+
Sbjct: 121 SYGGGMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYG 180
Query: 111 PRAG-----RDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGI 165
P +G RDYS YY IE+LR+QI A ++NA +L IDNA+LAA+DFRLKYE E +
Sbjct: 181 PGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCL 240
Query: 166 RLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNV 225
R +VEAD+ GL KV DDLT+ ++DLE+QIE ++LA L+K H+EE+ + G V V
Sbjct: 241 RQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTV 300
Query: 226 EVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQ 285
E++AAPG +L ++N+MR +YE +A++N +EA+E+F +Q+A LQ Q++ + + +
Sbjct: 301 EMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNE 360
Query: 286 LTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSN 345
+TEL+RT Q+LEIELQS L+MK SLE TL +T+A Y +QL+ +Q+ +S+LE ++ QI
Sbjct: 361 ITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGE 420
Query: 346 MERQNNEYHILLDIKTRLEQEIATYRRLLEGE----------------------DVKTTE 383
+ QN EY LLDIKTRLE EI TYRRLL+GE D+ + +
Sbjct: 421 TKCQNAEYKQLLDIKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGD 480
Query: 384 YQLSTL--EERDIKKTRKIKTVVQEVVDGKVVSSEVKEVEE 422
+ + + RD KTR KT+V+E+VDGKVVSS+V + E
Sbjct: 481 SRSGSCSGQGRDSSKTRVTKTIVEELVDGKVVSSQVSSISE 521
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 342 bits (877), Expect = 4e-94
Identities = 200/439 (45%), Positives = 273/439 (62%), Gaps = 33/439 (7%)
Query: 4 SRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGG--RGIRISNSRHTVNYGSDLTG 61
SR S RS+ S + G + + S G G G +S+ HT S G
Sbjct: 26 SRVSSIRSVGSCRVPSLAGAAGY--ISSARSGLSGLGSCLPGSYLSSECHT----SGFVG 79
Query: 62 GGDLFV-----GNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRD 116
G F G+EK MQ LNDRLA+YLEKVR LE+ N++LE +I++WYE P D
Sbjct: 80 SGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPD 139
Query: 117 YSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGL 176
Y +Y++ IE+ + +I + +NAR VLQIDNAKLAA+DFR KYETE +R VEAD+ GL
Sbjct: 140 YQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGL 199
Query: 177 NKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLG 236
++ D+LTL K DLE Q+E L ++L LKK H+EEV L LG+ +NVEVDAAP ++L
Sbjct: 200 RRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLN 259
Query: 237 VIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSL 296
I+ +MR +YE + + N ++ + F QT L QQV ++E+L+ + ++ ELRRT +L
Sbjct: 260 KILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNAL 319
Query: 297 EIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHIL 356
EIELQ+ SM+ SLE TL ET+ARYSSQLA +Q L+S++EAQL +IR ++ERQN EY +L
Sbjct: 320 EIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVL 379
Query: 357 LDIKTRLEQEIATYRRLLEGEDVKTTEYQLSTLEERDIKKT------------------- 397
LD+K RLE EIATYR LLEGED K +T + I+
Sbjct: 380 LDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCTPAPQV 439
Query: 398 -RKIKTVVQEVVDGKVVSS 415
+I+T+ +E+ DGKV+SS
Sbjct: 440 GTQIRTITEEIRDGKVISS 458
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 333 bits (855), Expect = 1e-91
Identities = 169/331 (51%), Positives = 239/331 (72%), Gaps = 5/331 (1%)
Query: 55 YGSDLTGGGDLF-----VGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETN 109
+ + +GGG F GNEK MQ+LNDRLA YLEKVR LEQ N+ LE +I++W E
Sbjct: 77 FATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQ 136
Query: 110 APRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTV 169
P DY +Y+R IEEL+ + ++ +NAR V++IDNAKLAA+DFR KYETE +R V
Sbjct: 137 VPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLV 196
Query: 170 EADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDA 229
E+D+ GL ++ DDLTL K+DLE Q+E L ++L LKK H+EEV+ L LG+ +NVEVDA
Sbjct: 197 ESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDA 256
Query: 230 APGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTEL 289
AP ++L ++ EMR +YE + + N ++A++ + Q+ L QQV ++E+L+ + ++ EL
Sbjct: 257 APPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIEL 316
Query: 290 RRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQ 349
RRT +LEIELQ+ SM+++LE TL ET+ARYSSQLA +Q +++++EAQL +IR+++ERQ
Sbjct: 317 RRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQ 376
Query: 350 NNEYHILLDIKTRLEQEIATYRRLLEGEDVK 380
N EY +LLD++ RLE EI TYR LLE ED K
Sbjct: 377 NQEYQVLLDVRARLECEINTYRGLLESEDSK 407
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 329 bits (843), Expect = 3e-90
Identities = 192/412 (46%), Positives = 260/412 (63%), Gaps = 19/412 (4%)
Query: 30 GTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGGG-----------DLFVGNEKMAMQNLN 78
G T V G G S YG L GG L GNEK+ MQNLN
Sbjct: 33 GNTCGVPGIGSGFSCAFGGSSSAGGYGGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLN 92
Query: 79 DRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGR----DYSAYYRQIEELRSQIKDA 134
DRLASYLE VR LE++N+ LE +IK WYE P + R DYS Y+ I+EL++QI A
Sbjct: 93 DRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISA 152
Query: 135 QLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQI 194
NA VLQ DNA+L A+DFRLK+E E + +VEAD+ GL +V D+LTL +TDLEIQ+
Sbjct: 153 TTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQL 212
Query: 195 EELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNL 254
E L+++LA LKK H+EE+ L G VNVE++AAPG++L V++N MR +YE +A++N
Sbjct: 213 ETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNR 272
Query: 255 QEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTL 314
++A+ F ++A LQQQ++ + +L E++RT Q+LEIELQS L+ K SLE +L
Sbjct: 273 RDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSL 332
Query: 315 EETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLL 374
ET++ Y +QLA +Q+ + +LE QL Q+R+ E Q EY LLDIK LE+EI TY L+
Sbjct: 333 TETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLI 392
Query: 375 EGED---VKTTEYQLSTLEERDIKKTRKIKTVVQEV-VDGKVVSSEVKEVEE 422
+GED K+ Y + +D KT +KTVV+E+ GKV+SS V VEE
Sbjct: 393 DGEDGSCSKSKGYGGPGNQTKDSSKTTIVKTVVEEIDPRGKVLSSRVHTVEE 444
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 326 bits (836), Expect = 2e-89
Identities = 175/344 (50%), Positives = 236/344 (68%), Gaps = 10/344 (2%)
Query: 37 GGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNS 96
GG GG G +G G G L GNEK+ MQNLNDRLASYL+KVR LE+SN
Sbjct: 120 GGFGGGGFG-------GGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNY 172
Query: 97 KLEVQIKQWYETNAPR---AGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAE 153
+LE +IK+WYE + RDYS YY+ I++L++QI + NA +LQIDNA+LAA+
Sbjct: 173 ELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAAD 232
Query: 154 DFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVD 213
DFRLKYE E +R +VEAD+ GL +V D+LTL K DLE+QIE L ++LA LKK H+EE+
Sbjct: 233 DFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMK 292
Query: 214 GLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVT 273
L VNVE++AAPG++L ++N MR +YE +A++N ++A+ F ++ L ++
Sbjct: 293 DLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEID 352
Query: 274 VNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLS 333
N E++ + ++TELRR Q+LEIELQS L++K+SLE +L ET+ RY QL+ +Q+ +S
Sbjct: 353 NNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQIS 412
Query: 334 SLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGE 377
+LE QL QIR+ E QN EY LLDIK RLE EI TYR LLEGE
Sbjct: 413 ALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGE 456
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 320 bits (819), Expect = 2e-87
Identities = 181/403 (44%), Positives = 264/403 (65%), Gaps = 15/403 (3%)
Query: 30 GTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVR 89
G SV GG+ G + N+ GS+ G L GNEK+ MQNLNDRLASYL+ VR
Sbjct: 51 GGLGSVPGGSHAGGA-LGNAACIGFAGSE----GGLLSGNEKVTMQNLNDRLASYLDNVR 105
Query: 90 TLEQSNSKLEVQIKQWYETNAPRAGR----DYSAYYRQIEELRSQIKDAQLQNARCVLQI 145
LE++N++LE +IK WYE P + R DYS Y+ IE+L+++I + NA +LQI
Sbjct: 106 ALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQI 165
Query: 146 DNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLK 205
DNA+LAA+DFRLKYE E + VEAD+ GL +V D+LTL +TD E+Q E L++++ LK
Sbjct: 166 DNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLK 225
Query: 206 KEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQT 265
K H+EE+ L G VNVE++AAPG++L V++N MR +YE +A++N ++A+ F ++
Sbjct: 226 KNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKS 285
Query: 266 AVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQL 325
A LQQQ++ ++ QLTE+RRT Q+LEI+LQS ++ K SLE +L ET++ Y +QL
Sbjct: 286 ASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQL 345
Query: 326 ANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQ 385
A +Q+ + +LE QL Q+R+ E Q EY LLD+K LE+EI TY RL++G+ ++ +
Sbjct: 346 AQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDGNSCSKSK 405
Query: 386 -----LSTLEERDIKKTRKIKTVVQEVVD-GKVVSSEVKEVEE 422
+D+ KT +KTVV+E+ GKV+SS + +EE
Sbjct: 406 GFGSGSPGNSSKDLSKTTLVKTVVEELDQRGKVLSSRIHSIEE 448
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 313 bits (802), Expect = 2e-85
Identities = 161/315 (51%), Positives = 225/315 (71%)
Query: 66 FVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIE 125
F GNEK MQ LNDRLASYL +VR LEQ N++LE +I++ + DY +++R IE
Sbjct: 92 FNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIE 151
Query: 126 ELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTL 185
EL+ +I + +NAR V+ IDNAKLAA+DFR KYE E +R VEAD+ GL ++ DDLTL
Sbjct: 152 ELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTL 211
Query: 186 HKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQK 245
K DLE Q+E L ++L LKK H+EEV L LG+ +N+EVDAAP ++L ++ EMR +
Sbjct: 212 CKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQ 271
Query: 246 YEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLS 305
YE M + N ++ +E F Q L QQV ++E+L+ + + +LRRT +LEIELQ+ S
Sbjct: 272 YEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHS 331
Query: 306 MKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQ 365
+++SLE+TL E++ARYSSQLA +Q +++++EAQL +IR+++ERQN EY +LLD++ RLE
Sbjct: 332 LRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEG 391
Query: 366 EIATYRRLLEGEDVK 380
EI TYR LLE ED K
Sbjct: 392 EINTYRSLLENEDCK 406
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 313 bits (801), Expect = 2e-85
Identities = 159/328 (48%), Positives = 235/328 (71%)
Query: 66 FVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIE 125
F G+EK MQ LNDRLASYLEKVR LE+ N++LE I++ + P Y +Y++ IE
Sbjct: 52 FNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIE 111
Query: 126 ELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTL 185
EL+ +I ++ +NAR V+QIDNAKLA++DFR KYETE +R VE+D+ GL ++ D+LTL
Sbjct: 112 ELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTL 171
Query: 186 HKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQK 245
++DLE Q+E L ++L LK+ H++EV+ L LG+ +NVEVDAAP ++L ++NE R +
Sbjct: 172 CRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQ 231
Query: 246 YEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLS 305
YE + + N +E ++ F QT L +QV ++E+L+ + ++ ELRRT +LEIELQ+ +
Sbjct: 232 YEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHN 291
Query: 306 MKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQ 365
+++SLE+TL E++ARYSSQL+ +Q L++++E+QL +IRS++ERQN EY +LLD++ RLE
Sbjct: 292 LRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLEC 351
Query: 366 EIATYRRLLEGEDVKTTEYQLSTLEERD 393
EI TYR LLE ED K +T D
Sbjct: 352 EINTYRSLLESEDCKLPSNPCATTNACD 379
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 312 bits (800), Expect = 3e-85
Identities = 164/394 (41%), Positives = 255/394 (64%), Gaps = 7/394 (1%)
Query: 33 PSVYGGAGGRGIRISNSRHTVNYGSDLTGGG---DLFVGNEKMAMQNLNDRLASYLEKVR 89
P+V+GGAGG I +S + + G G L GN K MQNLNDRLASYLEKVR
Sbjct: 32 PTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVR 91
Query: 90 TLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAK 149
LE++N KLE +I +W++ P + +DYS Y I L+ QI D ++ NA+ +L IDNA+
Sbjct: 92 ALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNAR 151
Query: 150 LAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQ 209
+A +DF LKYE E + +E +++GL + D+LT+ TDLE ++E + K+L L+KK H+
Sbjct: 152 MAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHE 211
Query: 210 EEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQ 269
+E++ H VNV+VD P +L ++ +MRQ+YE++ +K ++ ++ Q+A +
Sbjct: 212 QEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMS 271
Query: 270 QQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQ 329
Q+ + ++ + + EL+RT Q+LEI+LQ+ S K +LE+ L ET++RYS +L ++Q
Sbjct: 272 QE-AASPATVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQ 330
Query: 330 SLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQLSTL 389
++S E +L Q+R +ERQNNEY +LL IKT LE+EI TYRRLLEGE T E S++
Sbjct: 331 EIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGESEGTREESKSSM 390
Query: 390 EERDIKKTRKIKTVVQEVVDGKVVSSEVKEVEEN 423
+ + T KIK + QE ++G++V +V E++++
Sbjct: 391 K---VSATPKIKAITQETINGRLVLCQVNEIQKH 421
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 312 bits (799), Expect = 4e-85
Identities = 158/313 (50%), Positives = 230/313 (73%)
Query: 66 FVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIE 125
F G+EK MQ LNDRLASYLEKVR LE+ N++LE I++ + P Y +Y++ IE
Sbjct: 52 FNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIE 111
Query: 126 ELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTL 185
EL+ +I + +NAR V+QIDNAKLAA+DFR KY+TE +R VE+D+ GL ++ D+LTL
Sbjct: 112 ELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTL 171
Query: 186 HKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQK 245
K+DLE Q+E L ++L LK H++EV+ L LG+ +NVEVDAAP ++L ++NE R +
Sbjct: 172 CKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQ 231
Query: 246 YEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLS 305
YE + + N +E ++ F QT L +QV ++E+L+ + ++ ELRRT +LEIELQ+ +
Sbjct: 232 YEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHN 291
Query: 306 MKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQ 365
+++SLE+TL E++ARYSSQL+ +QSL++++E+QL +IRS++ERQN EY +LLD++ RLE
Sbjct: 292 LRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLEC 351
Query: 366 EIATYRRLLEGED 378
EI TYR LLE ED
Sbjct: 352 EINTYRSLLESED 364
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 311 bits (796), Expect = 9e-85
Identities = 156/315 (49%), Positives = 230/315 (73%)
Query: 66 FVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIE 125
F G+EK MQ LNDRLASYLEKVR LE+ N++LE I++ + P Y +Y++ IE
Sbjct: 94 FNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIE 153
Query: 126 ELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTL 185
EL+ +I A+ +NAR V+ IDNAKLA++DFR KY+TE+ +RL VE+D+ + ++ D+LTL
Sbjct: 154 ELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTL 213
Query: 186 HKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQK 245
K+DLE Q+E L ++L LKK H+EEV+ L LG+ +NVEVD AP ++L ++NE R +
Sbjct: 214 CKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQ 273
Query: 246 YEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLS 305
YE + + N +E ++ F QT L +QV ++E+L+ + ++ ELRRT +LEIELQ+ +
Sbjct: 274 YEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHN 333
Query: 306 MKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQ 365
+++SLE+TL E++A YSSQL+ +QSL++++E+QL +IR ++ERQN EY +LLD++ RLE
Sbjct: 334 LRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLEC 393
Query: 366 EIATYRRLLEGEDVK 380
EI TYR LLE ED K
Sbjct: 394 EINTYRSLLESEDCK 408
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 310 bits (795), Expect = 1e-84
Identities = 157/315 (49%), Positives = 232/315 (73%)
Query: 66 FVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIE 125
F G+EK MQ LNDRLASYLEKVR LE+ N++LE I++ + P Y +Y++ IE
Sbjct: 52 FNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIE 111
Query: 126 ELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTL 185
EL+ +I ++ +NAR V+QIDNAKLAA+DFR KY+TE+ +R VE+D+ L ++ D+LTL
Sbjct: 112 ELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTL 171
Query: 186 HKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQK 245
++DLE Q+E L ++L LK+ H++EV+ L LG+ +NVEVDAAP ++L ++NE R +
Sbjct: 172 CRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQ 231
Query: 246 YEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLS 305
YE + + N +E ++ F QT L +QV ++E+L+ + ++ ELRRT +LEIELQ+ +
Sbjct: 232 YEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHN 291
Query: 306 MKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQ 365
++ SLE+TL E++ARYSSQL+ +QSL++++E+QL +IRS++ERQN EY +LLD++ RLE
Sbjct: 292 LRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLEC 351
Query: 366 EIATYRRLLEGEDVK 380
EI TYR LLE ED K
Sbjct: 352 EINTYRSLLESEDCK 366
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 308 bits (790), Expect = 5e-84
Identities = 188/426 (44%), Positives = 263/426 (61%), Gaps = 18/426 (4%)
Query: 1 MDFSRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDLT 60
M F+ RS + SL + + G + + + SVY GAGG G RIS SR T G +
Sbjct: 1 MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS 60
Query: 61 GG----------GDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNA 110
GG G + NEK MQ+LNDRLASYL++VR+LE N +LE +I++ E
Sbjct: 61 GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG 120
Query: 111 PRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVE 170
P+ RD+S Y++ IE+LR+QI + NAR VLQIDNA+LAA+DFR+KYETE +R +VE
Sbjct: 121 PQV-RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVE 179
Query: 171 ADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNT-VNVEVDA 229
D+ GL KV DD + + LE +IE L ++L +KK H+EEV GL + ++ + VEVDA
Sbjct: 180 NDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDA 239
Query: 230 APGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTEL 289
+L IM ++R +Y+ +A+KN +E + + +Q VT + E+ E LTEL
Sbjct: 240 PKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTEL 299
Query: 290 RRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQ 349
RRT QSLEI+L S ++K SLE++L E +ARY+ Q+ L +L LE++L Q R+ +RQ
Sbjct: 300 RRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQ 359
Query: 350 NNEYHILLDIKTRLEQEIATYRRLLE-GEDVKTTEYQLSTLEERDIKKTRKIKTVVQEVV 408
EY LL+IK +LE EIATYRRLLE GED + S+ + I+ KT + +V
Sbjct: 360 AQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQ-----KTTTRRIV 414
Query: 409 DGKVVS 414
DGKVVS
Sbjct: 415 DGKVVS 420
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 308 bits (790), Expect = 5e-84
Identities = 188/426 (44%), Positives = 263/426 (61%), Gaps = 18/426 (4%)
Query: 1 MDFSRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDLT 60
M F+ RS + SL + + G + + + SVY GAGG G RIS SR T G +
Sbjct: 1 MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS 60
Query: 61 GG----------GDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNA 110
GG G + NEK MQ+LNDRLASYL++VR+LE N +LE +I++ E
Sbjct: 61 GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG 120
Query: 111 PRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVE 170
P+ RD+S Y++ IE+LR+QI + NAR VLQIDNA+LAA+DFR+KYETE +R +VE
Sbjct: 121 PQV-RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVE 179
Query: 171 ADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNT-VNVEVDA 229
D+ GL KV DD + + LE +IE L ++L +KK H+EEV GL + ++ + VEVDA
Sbjct: 180 NDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDA 239
Query: 230 APGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTEL 289
+L IM ++R +Y+ +A+KN +E + + +Q VT + E+ E LTEL
Sbjct: 240 PKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTEL 299
Query: 290 RRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQ 349
RRT QSLEI+L S ++K SLE++L E +ARY+ Q+ L +L LE++L Q R+ +RQ
Sbjct: 300 RRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQ 359
Query: 350 NNEYHILLDIKTRLEQEIATYRRLLE-GEDVKTTEYQLSTLEERDIKKTRKIKTVVQEVV 408
EY LL+IK +LE EIATYRRLLE GED + S+ + I+ KT + +V
Sbjct: 360 AQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQ-----KTTTRRIV 414
Query: 409 DGKVVS 414
DGKVVS
Sbjct: 415 DGKVVS 420
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 304 bits (779), Expect = 9e-83
Identities = 184/442 (41%), Positives = 270/442 (61%), Gaps = 29/442 (6%)
Query: 10 RSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDL----TGGGD- 64
R S+S ++ T G RL + +G GI S + +G TGGG+
Sbjct: 4 RLSSASRRSCPRPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNP 63
Query: 65 ----------LFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAG 114
L GNEK+ MQNLNDRLASYL+ V LE++N+ LE +IK WYE P +
Sbjct: 64 CAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSC 123
Query: 115 R----DYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVE 170
R DYS Y+ I++L++QI + NA VLQIDNA+L A+DFRLKYE E + +VE
Sbjct: 124 RGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVE 183
Query: 171 ADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAA 230
AD+ GL +V D++TL +TDLEIQ E L++++ LKK H+EE+ L G VNVE++AA
Sbjct: 184 ADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAA 243
Query: 231 PGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELR 290
PG++L V++N MR +YE +A++N ++A+ F ++A LQQQ++ + +LTE++
Sbjct: 244 PGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMK 303
Query: 291 RTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQN 350
RT Q+LEIELQS L+ K SLE +L ET++ Y +QLA +Q+ + +LE QL Q+R+ E Q
Sbjct: 304 RTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQK 363
Query: 351 NEYHILLDIKTRLEQEIATYRRLLEGED-------VKTTEYQLSTL--EERDIKKTRKIK 401
EY LLDIK LE+EI TY L+ G+D K+ +Y + + +D K +K
Sbjct: 364 LEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAIVVK 423
Query: 402 TVVQEVVD-GKVVSSEVKEVEE 422
V++EV K++++ + +EE
Sbjct: 424 KVLEEVDQRSKILTTRLHSLEE 445
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 294 bits (752), Expect = 1e-79
Identities = 153/324 (47%), Positives = 226/324 (69%)
Query: 65 LFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQI 124
+F NEK MQ LNDRLASYLEKVR+LE++N++LE +I++ E + P DY Y+ I
Sbjct: 84 VFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTI 143
Query: 125 EELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLT 184
E+L+ +I + +N+R +Q+DN KLA +DF+ KYE+E +R +EAD+ L+ + ++LT
Sbjct: 144 EDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELT 203
Query: 185 LHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQ 244
L K+DLE +E L +DL LKK H+EEV+ L + LG+ ++VE+D AP L+L +++EMR
Sbjct: 204 LCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRC 263
Query: 245 KYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHL 304
+ E + N +EA+E QT L QQ + E+L+G ++++ EL+RT+ +LEIELQ+
Sbjct: 264 QCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQ 323
Query: 305 SMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLE 364
S+ ESLE T+ ET+A+YSSQLA +Q L+ +LE QL +IR ++ERQN EY +LLD+K RLE
Sbjct: 324 SLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLE 383
Query: 365 QEIATYRRLLEGEDVKTTEYQLST 388
EI TY LL+ ED + + ST
Sbjct: 384 GEINTYWGLLDSEDSRLSCSPCST 407
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 290 bits (743), Expect = 1e-78
Identities = 170/372 (45%), Positives = 238/372 (63%), Gaps = 14/372 (3%)
Query: 65 LFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGR----DYSAY 120
L GNEK+ MQNLNDRLASYL+ V LE++N+ LE +IK YE P + R DYS Y
Sbjct: 78 LLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRY 137
Query: 121 YRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVF 180
+ IE+L+ QI A + NA VLQ DNA+L A+DFRLKYE E + +VEAD GL +V
Sbjct: 138 FSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVL 197
Query: 181 DDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMN 240
D+LTL TDLEIQ E L+++L LKK H+EE++ L G VNVE++A PG++L V++N
Sbjct: 198 DELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLN 257
Query: 241 EMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIEL 300
MR +YE +A++N ++A+ F ++A LQQQ++ + +LTEL+R Q+LEIEL
Sbjct: 258 NMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIEL 317
Query: 301 QSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIK 360
QS +++K S E +L ET+ Y +QL +Q + +E QL QIR+ E Q EY LLD+K
Sbjct: 318 QSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVK 377
Query: 361 TRLEQEIATYRRLLEGED--VKTTEYQL-------STLEERDIKKTRKIKTVVQEVVD-G 410
LE+EI Y LL+GE+ K+T Y+ S + +D + +KTVV+E+ G
Sbjct: 378 IFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEETIVKTVVEELDQIG 437
Query: 411 KVVSSEVKEVEE 422
++S V VEE
Sbjct: 438 NLLSLRVHSVEE 449
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 287 bits (734), Expect = 1e-77
Identities = 151/344 (43%), Positives = 221/344 (64%), Gaps = 13/344 (3%)
Query: 34 SVYGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQ 93
S +GG GG G G G G + NEK MQ LN RLASYL+KV+ LE+
Sbjct: 129 SGFGGFGGFG------------GGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEE 176
Query: 94 SNSKLEVQIKQWYETNAPRA-GRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAA 152
+N+ LE +I+ WY+ P A ++YS YY I++L+ QI D + N + +L IDN ++
Sbjct: 177 ANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTL 236
Query: 153 EDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEV 212
+DFR+K+E E+ +R V+AD+ GL +V D+LT+ K+DLE+Q E L ++L LKK H+EE+
Sbjct: 237 DDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEM 296
Query: 213 DGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQV 272
L VNVE++ APG +L +N+MRQ+YE + KN ++ + Q+E Q ++ +V
Sbjct: 297 SQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEV 356
Query: 273 TVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLL 332
+ + +E++ + ++T+LR Q LEIELQS LS K +LE +LE+TK RY QL +Q +
Sbjct: 357 SSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQI 416
Query: 333 SSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEG 376
S+LEAQ+ +R +E QN EY +LL IK RLE+EI TY LLEG
Sbjct: 417 SNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG 460
>gi|15431318 keratin 38 [Homo sapiens]
Length = 456
Score = 278 bits (711), Expect = 7e-75
Identities = 145/319 (45%), Positives = 215/319 (67%)
Query: 62 GGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYY 121
G + G+EK MQ LNDRLA+YLEKVR LEQ N++LE + + + + DY +Y+
Sbjct: 96 GENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQSYF 155
Query: 122 RQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFD 181
IEEL+ +I ++ +NAR ++QIDNAKLAA+DFR+K E+ER +R VEAD G K+ D
Sbjct: 156 HTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLD 215
Query: 182 DLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNE 241
D TL K DLE Q E L ++ LK H++EV L LG + +E+D P ++L ++ E
Sbjct: 216 DATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGE 275
Query: 242 MRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQ 301
MR +YE M + N Q+ ++ F+ Q+ + Q +EEL+ + ++ ELR T +LE+E Q
Sbjct: 276 MRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQ 335
Query: 302 SHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKT 361
+ ++K+ L+++L E + R+ ++LA +QSL+S++E QL +IR+++ERQN EY +LLD+KT
Sbjct: 336 AQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKT 395
Query: 362 RLEQEIATYRRLLEGEDVK 380
RLE EIATYR LLE ED K
Sbjct: 396 RLENEIATYRNLLESEDCK 414
>gi|55770882 keratin 37 [Homo sapiens]
Length = 449
Score = 278 bits (710), Expect = 9e-75
Identities = 145/319 (45%), Positives = 213/319 (66%)
Query: 62 GGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYY 121
G + G+EK M+ LNDRLA+YLEKVR LEQ N++LE + + + + DY +Y+
Sbjct: 96 GKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYF 155
Query: 122 RQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFD 181
R IEEL+ +I ++ +NAR ++QIDNAKLAA+DFR+K E+ER + VEAD G K+ D
Sbjct: 156 RTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLD 215
Query: 182 DLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNE 241
D TL K DLE Q E L ++ LK H++EV L LG +E+D P ++L ++ E
Sbjct: 216 DATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGE 275
Query: 242 MRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQ 301
MR +YE M + N Q+ ++ F+ Q+ + Q +EEL+ + ++ ELR T +LE+E Q
Sbjct: 276 MRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQ 335
Query: 302 SHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKT 361
+ ++K+ L+++L E + RY ++LA +QSL+S+LE QL +IR+++ERQN EY +LLD+K
Sbjct: 336 AQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKA 395
Query: 362 RLEQEIATYRRLLEGEDVK 380
RLE EIATYR LLE ED K
Sbjct: 396 RLENEIATYRNLLESEDCK 414
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 273 bits (699), Expect = 2e-73
Identities = 159/393 (40%), Positives = 232/393 (59%), Gaps = 35/393 (8%)
Query: 58 DLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDY 117
D + G+ NEK MQ LN+RLA+YL+KVR LE+ N++LE +I++ P DY
Sbjct: 84 DCSWYGEGINSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDY 143
Query: 118 SAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLN 177
+YY IEEL+ +I + +N+R V QIDN KL A+D R KYE E +R VE+D GL
Sbjct: 144 LSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLK 203
Query: 178 KVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGV 237
++ + LTL K DLE Q++ L ++L LK H+EE++ L LG +++EV AAP +L
Sbjct: 204 QILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQ 263
Query: 238 IMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLE 297
++ EMR +YE + + N ++ ++ F Q L QQV ++++ + + ++ ELRR+ +LE
Sbjct: 264 VLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLE 323
Query: 298 IELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILL 357
+ELQ+ M++S E L ET+ARY++ L +QSL+ +LEAQL +IR +ERQN EY ILL
Sbjct: 324 VELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILL 383
Query: 358 DIKTRLEQEIATYRRLLEGEDVKTTEYQLSTLEERD---------IKKTR---------- 398
D+K+RLE EI TYR LLE D K Y +T E I+ T
Sbjct: 384 DVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKSGAIESTAPACTSSSPCS 443
Query: 399 ----------------KIKTVVQEVVDGKVVSS 415
KI T+ +E+ DGKV+SS
Sbjct: 444 LKEHCSACGPLSRILVKICTITKEIKDGKVISS 476
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,174,868
Number of Sequences: 37866
Number of extensions: 551505
Number of successful extensions: 5099
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 248
Number of HSP's successfully gapped in prelim test: 602
Number of HSP's that attempted gapping in prelim test: 2675
Number of HSP's gapped (non-prelim): 1937
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.