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Search of human proteins with 27765087
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27765087 calpastatin isoform c [Homo sapiens]
(430 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27765087 calpastatin isoform c [Homo sapiens] 865 0.0
gi|109637771 calpastatin isoform l [Homo sapiens] 781 0.0
gi|109637769 calpastatin isoform k [Homo sapiens] 781 0.0
gi|109637767 calpastatin isoform j [Homo sapiens] 781 0.0
gi|109637765 calpastatin isoform i [Homo sapiens] 781 0.0
gi|109637763 calpastatin isoform h [Homo sapiens] 781 0.0
gi|109637761 calpastatin isoform g [Homo sapiens] 781 0.0
gi|109637759 calpastatin isoform f [Homo sapiens] 781 0.0
gi|109637757 calpastatin isoform e [Homo sapiens] 781 0.0
gi|27765085 calpastatin isoform b [Homo sapiens] 781 0.0
gi|109637753 calpastatin isoform a [Homo sapiens] 781 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 76 5e-14
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 57 3e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 57 4e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 57 4e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 56 7e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 56 7e-08
gi|217330641 IWS1 homolog [Homo sapiens] 55 1e-07
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 55 1e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 54 4e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 53 5e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 51 2e-06
gi|16445033 ACRC protein [Homo sapiens] 49 7e-06
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 49 1e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 49 1e-05
gi|104526627 triadin [Homo sapiens] 49 1e-05
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 48 2e-05
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 47 3e-05
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 47 3e-05
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 47 3e-05
>gi|27765087 calpastatin isoform c [Homo sapiens]
Length = 430
Score = 865 bits (2234), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%)
Query: 1 MGQFLSSTFLEGSPATVWHDKLCDGERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPS 60
MGQFLSSTFLEGSPATVWHDKLCDGERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPS
Sbjct: 1 MGQFLSSTFLEGSPATVWHDKLCDGERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPS 60
Query: 61 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 120
EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA
Sbjct: 61 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 120
Query: 121 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 180
AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK
Sbjct: 121 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 180
Query: 181 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 240
VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE
Sbjct: 181 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 240
Query: 241 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSL 300
DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSL
Sbjct: 241 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSL 300
Query: 301 GQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKS 360
GQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKS
Sbjct: 301 GQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKS 360
Query: 361 EDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKT 420
EDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKT
Sbjct: 361 EDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKT 420
Query: 421 TEETSKPKDD 430
TEETSKPKDD
Sbjct: 421 TEETSKPKDD 430
>gi|109637771 calpastatin isoform l [Homo sapiens]
Length = 654
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 262 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 321
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 322 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 381
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 382 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 441
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 442 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 501
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 502 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 561
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 562 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 621
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 622 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
Score = 200 bits (508), Expect = 2e-51
Identities = 140/395 (35%), Positives = 212/395 (53%), Gaps = 41/395 (10%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR E KP + ID LS DF
Sbjct: 150 IEELGKREVTIPPKYR----------------ELLAKPIGPDDAIDALSSDFTCGS---- 189
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 190 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 243
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 244 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 302
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 303 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 362
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 363 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 422
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 423 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 480
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 481 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 515
Score = 115 bits (288), Expect = 8e-26
Identities = 98/301 (32%), Positives = 144/301 (47%), Gaps = 44/301 (14%)
Query: 110 KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG-KKE 168
KP +K +E K+ PA ++S P +P+ G D A++ L D+LG +E
Sbjct: 82 KPGDKKKEKKSLTPA-----------VPVESKPDKPSGKSGM--DAALDDLIDTLGGPEE 128
Query: 169 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 228
+ E+ +V + E+LG++E TIPP YR LL K P
Sbjct: 129 TEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR----------ELLAK-------P 171
Query: 229 MSEDFLLDALSEDFS-GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----RDT 283
+ D +DALS DF+ G A+ K E + +EV+ A T ++ APP R
Sbjct: 172 IGPDDAIDALSSDFTCGSPTAAGKKTEKEE----STEVLKAQSAGTVRSAAPPQEKKRKV 227
Query: 284 SSDKDLDDALDKLSDSLGQRQPDPD-ENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
D D AL+ LS SLG RQ +P+ + + +++ + KAK E +K GE D+TIP EYR
Sbjct: 228 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 287
Query: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
DK KP + E+ KP + + ID LS D D + S+ T K + KAA
Sbjct: 288 ---KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 344
Query: 403 S 403
+
Sbjct: 345 A 345
Score = 63.5 bits (153), Expect = 3e-10
Identities = 62/256 (24%), Positives = 106/256 (41%), Gaps = 29/256 (11%)
Query: 178 MDKVKEKAKEEDREKLGE--KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLL 235
M+ + KA + + EK + K +++P D K + + +++Q S +
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
Query: 236 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDK 295
+G ++ + + K E S TPA ++ P S +D ALD
Sbjct: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSGKSGMDAALDD 118
Query: 296 LSDSLGQRQPDPDENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVK 354
L D+LG + +EN +V + + + ++LG+R+ TIPP+YR LL
Sbjct: 119 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELL---------- 168
Query: 355 PPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKA 414
KP D IDALS D +C S T + T K++ + + A G
Sbjct: 169 ---------AKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTV 214
Query: 415 KDSAKTTEETSKPKDD 430
+ +A E+ K + D
Sbjct: 215 RSAAPPQEKKRKVEKD 230
>gi|109637769 calpastatin isoform k [Homo sapiens]
Length = 673
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 281 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 340
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 341 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 400
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 401 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 460
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 461 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 520
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 521 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 580
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 581 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 640
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 641 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 673
Score = 200 bits (508), Expect = 2e-51
Identities = 140/395 (35%), Positives = 212/395 (53%), Gaps = 41/395 (10%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR E KP + ID LS DF
Sbjct: 169 IEELGKREVTIPPKYR----------------ELLAKPIGPDDAIDALSSDFTCGS---- 208
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 209 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 262
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 263 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 321
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 322 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 381
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 382 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 441
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 442 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 499
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 500 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 534
Score = 115 bits (288), Expect = 8e-26
Identities = 98/301 (32%), Positives = 144/301 (47%), Gaps = 44/301 (14%)
Query: 110 KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG-KKE 168
KP +K +E K+ PA ++S P +P+ G D A++ L D+LG +E
Sbjct: 101 KPGDKKKEKKSLTPA-----------VPVESKPDKPSGKSGM--DAALDDLIDTLGGPEE 147
Query: 169 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 228
+ E+ +V + E+LG++E TIPP YR LL K P
Sbjct: 148 TEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR----------ELLAK-------P 190
Query: 229 MSEDFLLDALSEDFS-GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----RDT 283
+ D +DALS DF+ G A+ K E + +EV+ A T ++ APP R
Sbjct: 191 IGPDDAIDALSSDFTCGSPTAAGKKTEKEE----STEVLKAQSAGTVRSAAPPQEKKRKV 246
Query: 284 SSDKDLDDALDKLSDSLGQRQPDPD-ENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
D D AL+ LS SLG RQ +P+ + + +++ + KAK E +K GE D+TIP EYR
Sbjct: 247 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 306
Query: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
DK KP + E+ KP + + ID LS D D + S+ T K + KAA
Sbjct: 307 ---KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 363
Query: 403 S 403
+
Sbjct: 364 A 364
Score = 67.4 bits (163), Expect = 2e-11
Identities = 63/266 (23%), Positives = 108/266 (40%), Gaps = 27/266 (10%)
Query: 166 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 225
K E + + + V EK +E + K + +++P D K + + +++Q
Sbjct: 10 KTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 69
Query: 226 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSS 285
S + +G ++ + + K E S TPA ++ P S
Sbjct: 70 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSG 127
Query: 286 DKDLDDALDKLSDSLGQRQPDPDENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLL 344
+D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR LL
Sbjct: 128 KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELL 187
Query: 345 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 404
KP D IDALS D +C S T + T K++ + +
Sbjct: 188 -------------------AKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKA 227
Query: 405 SKAPKNGGKAKDSAKTTEETSKPKDD 430
A G + +A E+ K + D
Sbjct: 228 QSA----GTVRSAAPPQEKKRKVEKD 249
>gi|109637767 calpastatin isoform j [Homo sapiens]
Length = 667
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 275 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 334
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 335 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 394
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 395 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 454
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 455 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 514
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 515 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 574
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 575 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 634
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 635 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
Score = 206 bits (525), Expect = 3e-53
Identities = 142/395 (35%), Positives = 218/395 (55%), Gaps = 28/395 (7%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 150 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGS---- 202
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 203 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 256
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 257 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 315
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 316 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 375
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 376 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 435
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 436 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 493
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 494 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 528
Score = 122 bits (306), Expect = 6e-28
Identities = 100/301 (33%), Positives = 150/301 (49%), Gaps = 31/301 (10%)
Query: 110 KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG-KKE 168
KP +K +E K+ PA ++S P +P+ G D A++ L D+LG +E
Sbjct: 82 KPGDKKKEKKSLTPA-----------VPVESKPDKPSGKSGM--DAALDDLIDTLGGPEE 128
Query: 169 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 228
+ E+ +V + E+LG++E TIPP YR E + K+G P +S + P
Sbjct: 129 TEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR-ELLAKKEGITGPPADSSK---P 184
Query: 229 MSEDFLLDALSEDFS-GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----RDT 283
+ D +DALS DF+ G A+ K E + +EV+ A T ++ APP R
Sbjct: 185 IGPDDAIDALSSDFTCGSPTAAGKKTEKEE----STEVLKAQSAGTVRSAAPPQEKKRKV 240
Query: 284 SSDKDLDDALDKLSDSLGQRQPDPD-ENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
D D AL+ LS SLG RQ +P+ + + +++ + KAK E +K GE D+TIP EYR
Sbjct: 241 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 300
Query: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
DK KP + E+ KP + + ID LS D D + S+ T K + KAA
Sbjct: 301 ---KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 357
Query: 403 S 403
+
Sbjct: 358 A 358
Score = 71.2 bits (173), Expect = 2e-12
Identities = 66/256 (25%), Positives = 112/256 (43%), Gaps = 16/256 (6%)
Query: 178 MDKVKEKAKEEDREKLGE--KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLL 235
M+ + KA + + EK + K +++P D K + + +++Q S +
Sbjct: 1 MNPTETKAVKTEPEKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKT 60
Query: 236 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDK 295
+G ++ + + K E S TPA ++ P S +D ALD
Sbjct: 61 KPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSGKSGMDAALDD 118
Query: 296 LSDSLGQRQPDPDENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVK 354
L D+LG + +EN +V + + + ++LG+R+ TIPP+YR LL ++
Sbjct: 119 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITG 176
Query: 355 PPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKA 414
PP DS KP D IDALS D +C S T + T K++ + + A G
Sbjct: 177 PPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTV 227
Query: 415 KDSAKTTEETSKPKDD 430
+ +A E+ K + D
Sbjct: 228 RSAAPPQEKKRKVEKD 243
>gi|109637765 calpastatin isoform i [Homo sapiens]
Length = 708
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 316 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 375
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 376 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 435
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 436 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 495
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 496 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 555
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 556 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 615
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 616 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 675
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 676 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 708
Score = 206 bits (525), Expect = 3e-53
Identities = 142/395 (35%), Positives = 218/395 (55%), Gaps = 28/395 (7%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 191 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGS---- 243
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 244 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 297
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 298 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 356
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 357 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 416
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 417 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 476
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 477 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 534
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 535 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 569
Score = 122 bits (306), Expect = 6e-28
Identities = 100/301 (33%), Positives = 150/301 (49%), Gaps = 31/301 (10%)
Query: 110 KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG-KKE 168
KP +K +E K+ PA ++S P +P+ G D A++ L D+LG +E
Sbjct: 123 KPGDKKKEKKSLTPA-----------VPVESKPDKPSGKSGM--DAALDDLIDTLGGPEE 169
Query: 169 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 228
+ E+ +V + E+LG++E TIPP YR E + K+G P +S + P
Sbjct: 170 TEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR-ELLAKKEGITGPPADSSK---P 225
Query: 229 MSEDFLLDALSEDFS-GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----RDT 283
+ D +DALS DF+ G A+ K E + +EV+ A T ++ APP R
Sbjct: 226 IGPDDAIDALSSDFTCGSPTAAGKKTEKEE----STEVLKAQSAGTVRSAAPPQEKKRKV 281
Query: 284 SSDKDLDDALDKLSDSLGQRQPDPD-ENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
D D AL+ LS SLG RQ +P+ + + +++ + KAK E +K GE D+TIP EYR
Sbjct: 282 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 341
Query: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
DK KP + E+ KP + + ID LS D D + S+ T K + KAA
Sbjct: 342 ---KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 398
Query: 403 S 403
+
Sbjct: 399 A 399
Score = 75.1 bits (183), Expect = 1e-13
Identities = 67/266 (25%), Positives = 114/266 (42%), Gaps = 14/266 (5%)
Query: 166 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 225
K E + + + V EK +E + K + +++P D K + + +++Q
Sbjct: 32 KTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 91
Query: 226 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSS 285
S + +G ++ + + K E S TPA ++ P S
Sbjct: 92 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSG 149
Query: 286 DKDLDDALDKLSDSLGQRQPDPDENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLL 344
+D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR LL
Sbjct: 150 KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELL 209
Query: 345 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 404
++ PP DS KP D IDALS D +C S T + T K++ + +
Sbjct: 210 AK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKA 262
Query: 405 SKAPKNGGKAKDSAKTTEETSKPKDD 430
A G + +A E+ K + D
Sbjct: 263 QSA----GTVRSAAPPQEKKRKVEKD 284
>gi|109637763 calpastatin isoform h [Homo sapiens]
Length = 769
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 377 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 436
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 437 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 496
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 497 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 556
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 557 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 616
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 617 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 676
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 677 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 736
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 737 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 769
Score = 206 bits (525), Expect = 3e-53
Identities = 142/395 (35%), Positives = 218/395 (55%), Gaps = 28/395 (7%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 252 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGS---- 304
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 305 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 358
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 359 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 417
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 418 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 477
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 478 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 537
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 538 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 595
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 596 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 630
Score = 91.3 bits (225), Expect = 2e-18
Identities = 87/358 (24%), Positives = 145/358 (40%), Gaps = 16/358 (4%)
Query: 76 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 133
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 134 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 193
SA A+ T ++ K E + + + V EK +E + K
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKE 120
Query: 194 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF 253
+ +++P D K + + +++Q S + +G ++ + +
Sbjct: 121 HTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 180
Query: 254 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPM 313
K E S TPA + + P S +D ALD L D+LG + +EN
Sbjct: 181 ISGKPGDKKKEKKSLTPAVPVE--SKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTY 238
Query: 314 E-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDP 372
+V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP D
Sbjct: 239 TGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIGPDDA 292
Query: 373 IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
IDALS D +C S T + T K++ + + A G + +A E+ K + D
Sbjct: 293 IDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVEKD 345
>gi|109637761 calpastatin isoform g [Homo sapiens]
Length = 772
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 380 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 439
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 440 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 499
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 500 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 559
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 560 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 619
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 620 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 679
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 680 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 739
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 740 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 772
Score = 206 bits (525), Expect = 3e-53
Identities = 142/395 (35%), Positives = 218/395 (55%), Gaps = 28/395 (7%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 255 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGS---- 307
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 308 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 361
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 362 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 420
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 421 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 480
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 481 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 540
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 541 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 598
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 599 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 633
Score = 83.2 bits (204), Expect = 4e-16
Identities = 90/363 (24%), Positives = 150/363 (41%), Gaps = 23/363 (6%)
Query: 76 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 133
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 134 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 190
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
Query: 191 EKLGE--KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNA 248
EK + K +++P D K + + +++Q S + +G ++
Sbjct: 119 EKKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESV 178
Query: 249 SSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPD 308
+ + K E S TPA ++ P S +D ALD L D+LG + +
Sbjct: 179 AGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSGKSGMDAALDDLIDTLGGPEETEE 236
Query: 309 ENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPA 367
EN +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 237 ENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPI 290
Query: 368 DDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKP 427
D IDALS D +C S T + T K++ + + A G + +A E+ K
Sbjct: 291 GPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKV 345
Query: 428 KDD 430
+ D
Sbjct: 346 EKD 348
>gi|109637759 calpastatin isoform f [Homo sapiens]
Length = 750
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 358 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 417
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 418 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 477
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 478 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 537
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 538 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 597
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 598 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 657
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 658 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 717
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 718 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 750
Score = 206 bits (525), Expect = 3e-53
Identities = 142/395 (35%), Positives = 218/395 (55%), Gaps = 28/395 (7%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 233 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGS---- 285
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 286 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 339
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 340 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 398
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 399 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 458
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 459 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 518
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 519 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 576
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 577 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 611
Score = 81.6 bits (200), Expect = 1e-15
Identities = 89/362 (24%), Positives = 148/362 (40%), Gaps = 43/362 (11%)
Query: 76 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEK--TEESKAAAPAPVSEAVC 131
+ +P +KP PR + + + E PSKP EK ++E KAA
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAA---------- 50
Query: 132 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDRE 191
S+ S+ GT V A + + K + M+ + KA + + E
Sbjct: 51 -----SLGSSQSSRTYAGGTASATKVSASSGATSKSSS--------MNPTETKAVKTEPE 97
Query: 192 KLGE--KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNAS 249
K + K +++P D K + + +++Q S + +G ++ +
Sbjct: 98 KKSQSTKPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVA 157
Query: 250 SLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDE 309
+ K E S TPA ++ P S +D ALD L D+LG + +E
Sbjct: 158 GITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSGKSGMDAALDDLIDTLGGPEETEEE 215
Query: 310 NKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD 368
N +V + + + ++LG+R+ TIPP+YR LL ++ PP DS KP
Sbjct: 216 NTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK--KEGITGPPA----DSSKPIG 269
Query: 369 DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 428
D IDALS D +C S T + T K++ + + A G + +A E+ K +
Sbjct: 270 PDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVE 324
Query: 429 DD 430
D
Sbjct: 325 KD 326
>gi|109637757 calpastatin isoform e [Homo sapiens]
Length = 756
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 364 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 423
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 424 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 483
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 484 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 543
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 544 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 603
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 604 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 663
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 664 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 723
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 724 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 756
Score = 200 bits (508), Expect = 2e-51
Identities = 140/395 (35%), Positives = 212/395 (53%), Gaps = 41/395 (10%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR E KP + ID LS DF
Sbjct: 252 IEELGKREVTIPPKYR----------------ELLAKPIGPDDAIDALSSDFTCGS---- 291
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 292 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 345
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 346 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 404
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 405 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 464
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 465 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 524
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 525 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 582
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 583 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 617
Score = 83.6 bits (205), Expect = 3e-16
Identities = 83/358 (23%), Positives = 139/358 (38%), Gaps = 29/358 (8%)
Query: 76 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 133
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 134 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 193
SA A+ T ++ K E + + + V EK +E + K
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKE 120
Query: 194 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF 253
+ +++P D K + + +++Q S + +G ++ + +
Sbjct: 121 HTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 180
Query: 254 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPM 313
K E S TPA + + P S +D ALD L D+LG + +EN
Sbjct: 181 ISGKPGDKKKEKKSLTPAVPVE--SKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTY 238
Query: 314 E-DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDP 372
+V + + + ++LG+R+ TIPP+YR LL KP D
Sbjct: 239 TGPEVSDPMSSTYIEELGKREVTIPPKYRELL-------------------AKPIGPDDA 279
Query: 373 IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
IDALS D +C S T + T K++ + + A G + +A E+ K + D
Sbjct: 280 IDALSSDF-TCGSPTAAGKKTEKEESTEVLKAQSA----GTVRSAAPPQEKKRKVEKD 332
>gi|27765085 calpastatin isoform b [Homo sapiens]
Length = 686
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 294 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 353
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 354 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 413
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 414 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 473
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 474 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 533
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 534 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 593
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 594 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 653
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 654 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 686
Score = 206 bits (525), Expect = 3e-53
Identities = 142/395 (35%), Positives = 218/395 (55%), Gaps = 28/395 (7%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 169 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGS---- 221
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 222 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 275
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 276 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 334
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 335 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 394
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 395 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 454
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 455 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 512
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 513 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 547
Score = 122 bits (306), Expect = 6e-28
Identities = 100/301 (33%), Positives = 150/301 (49%), Gaps = 31/301 (10%)
Query: 110 KPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLG-KKE 168
KP +K +E K+ PA ++S P +P+ G D A++ L D+LG +E
Sbjct: 101 KPGDKKKEKKSLTPA-----------VPVESKPDKPSGKSGM--DAALDDLIDTLGGPEE 147
Query: 169 ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPP 228
+ E+ +V + E+LG++E TIPP YR E + K+G P +S + P
Sbjct: 148 TEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR-ELLAKKEGITGPPADSSK---P 203
Query: 229 MSEDFLLDALSEDFS-GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----RDT 283
+ D +DALS DF+ G A+ K E + +EV+ A T ++ APP R
Sbjct: 204 IGPDDAIDALSSDFTCGSPTAAGKKTEKEE----STEVLKAQSAGTVRSAAPPQEKKRKV 259
Query: 284 SSDKDLDDALDKLSDSLGQRQPDPD-ENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
D D AL+ LS SLG RQ +P+ + + +++ + KAK E +K GE D+TIP EYR
Sbjct: 260 EKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 319
Query: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
DK KP + E+ KP + + ID LS D D + S+ T K + KAA
Sbjct: 320 ---KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 376
Query: 403 S 403
+
Sbjct: 377 A 377
Score = 75.1 bits (183), Expect = 1e-13
Identities = 67/266 (25%), Positives = 114/266 (42%), Gaps = 14/266 (5%)
Query: 166 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ 225
K E + + + V EK +E + K + +++P D K + + +++Q
Sbjct: 10 KTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 69
Query: 226 LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSS 285
S + +G ++ + + K E S TPA ++ P S
Sbjct: 70 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSG 127
Query: 286 DKDLDDALDKLSDSLGQRQPDPDENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLL 344
+D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR LL
Sbjct: 128 KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELL 187
Query: 345 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 404
++ PP DS KP D IDALS D +C S T + T K++ + +
Sbjct: 188 AK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKA 240
Query: 405 SKAPKNGGKAKDSAKTTEETSKPKDD 430
A G + +A E+ K + D
Sbjct: 241 QSA----GTVRSAAPPQEKKRKVEKD 262
>gi|109637753 calpastatin isoform a [Homo sapiens]
Length = 791
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 399 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 458
Query: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 459 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 518
Query: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 519 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 578
Query: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 579 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 638
Query: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 639 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 698
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 699 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 758
Query: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 759 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
Score = 206 bits (525), Expect = 3e-53
Identities = 142/395 (35%), Positives = 218/395 (55%), Gaps = 28/395 (7%)
Query: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEK 107
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 274 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGS---- 326
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGTVPDDAVEALADS 163
P+ +KTE+ ++ +E + S +++SA P + K T+ D A+EAL+ S
Sbjct: 327 PTAAGKKTEKEES------TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 380
Query: 164 LGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKES 222
LG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 381 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-EP 439
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTTQ 275
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T + Q
Sbjct: 440 EEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ 499
Query: 276 AGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT 335
+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++T
Sbjct: 500 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 559
Query: 336 IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK 395
IPP+YR + KP+ P K+S++ P + +DALS D + + AK
Sbjct: 560 IPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 617
Query: 396 DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+ P + +A + T ++ K DD
Sbjct: 618 LAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 652
Score = 82.8 bits (203), Expect = 5e-16
Identities = 100/386 (25%), Positives = 159/386 (41%), Gaps = 50/386 (12%)
Query: 76 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 133
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 134 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 190
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
Query: 191 EKLGEKEETIPPDYRLEEVKDKDGKPL-------LPKES----------KEQLPPMSEDF 233
EK + + + E K ++GKP LPK++ K+ + +E
Sbjct: 119 EKKSQSTKLSV----VHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 174
Query: 234 LLDALSEDFSGPQNASSLKFEDAKLAAAIS--------EVVSQTPASTTQAGAPPRDTSS 285
+ +E + PQ+ S E AIS E S TPA ++ P S
Sbjct: 175 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSG 232
Query: 286 DKDLDDALDKLSDSLGQRQPDPDENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLL 344
+D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR LL
Sbjct: 233 KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELL 292
Query: 345 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 404
++ PP DS KP D IDALS D +C S T + T K++ + +
Sbjct: 293 AK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKA 345
Query: 405 SKAPKNGGKAKDSAKTTEETSKPKDD 430
A G + +A E+ K + D
Sbjct: 346 QSA----GTVRSAAPPQEKKRKVEKD 367
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 76.3 bits (186), Expect = 5e-14
Identities = 97/418 (23%), Positives = 170/418 (40%), Gaps = 47/418 (11%)
Query: 38 QDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSE 97
+++A+ EE+ + ++ P + P ++ P + EK + +S +E+ S
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEV---KSP 547
Query: 98 DFDRSECKEKPSKPTE--KTEESKAAAPAPVSEAVCRTSMCSIQSAPP----EPATLKGT 151
+ +S KE+ P E E+ +A +PA V S ++ P P K
Sbjct: 548 EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP 607
Query: 152 VPDDAVE-ALADSLGKKEA-------DPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 203
V ++A A A S K+EA PE K KE+AK ++ K EKEE P+
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK---SPTKEEAKSPEKAKSPEKEEAKSPE 664
Query: 204 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 263
VK + P K S + S + + E+ P+ A S E+AK
Sbjct: 665 KAKSPVKAEAKSPEKAK-SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723
Query: 264 EVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSD----SLGQRQPDPDENKPMEDKVKE 319
V + + +A +P ++ + + + +K S + P +E + DK E
Sbjct: 724 SPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783
Query: 320 KAKAEHRDKLGE--------RDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQD 371
KAK+ ++++ ++D PE + + + VK P K+ E ++ +
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPE-----KEIPKKEEVKSPVKEEEKPQEVKVKEP 838
Query: 372 PIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKD 429
P A + + P+T +T + KD K+ A +AP K K K KPK+
Sbjct: 839 PKKA---EEEKAPATPKTEEK--KDSKKEEAPKKEAP----KPKVEEKKEPAVEKPKE 887
Score = 73.9 bits (180), Expect = 3e-13
Identities = 102/427 (23%), Positives = 167/427 (39%), Gaps = 57/427 (13%)
Query: 26 ERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKP 85
E + +A +++AK+ E E+ ++ P+E + K PE+ P
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS-PAEVKSPEKAKSPTKEEAKSPEKAKSP 655
Query: 86 RSESELIDELSEDFDRSECK--EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 143
E E ++ ++E K EK P + +S A +PV E ++ P
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE----------EAKSP 705
Query: 144 EPATLKGTVPDDAVEA-LADSLGKKEAD-PEDGKPVMDKVKEKAKEEDREKLGEKEETIP 201
E A K V ++A A S K+EA PE K VKE+AK ++ K EK +T+
Sbjct: 706 EKA--KSPVKEEAKSPEKAKSPVKEEAKTPEKAK---SPVKEEAKSPEKAKSPEKAKTL- 759
Query: 202 PDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAA- 260
+VK + K +E++ E + E+ P+ A S EDAK
Sbjct: 760 ------DVKSPEAKTPAKEEARSPADKFPEK-AKSPVKEEVKSPEKAKSPLKEDAKAPEK 812
Query: 261 -------AISEVVSQTPASTTQAGAPPRDTSSDK-DLDDALDKLSDSLGQRQPDPDENKP 312
S V + + PP+ +K ++ DS + P + KP
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Query: 313 MEDKVKEKA-------KAEHRDKLGERDDTIP-PEYRHLLDDNGQDKPVKPPTKKSEDSK 364
++ KE A K E + + E +P PE ++ P K K+ K
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE---------KEAPAKVEVKEDAKPK 923
Query: 365 KPAD--DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKT-T 421
+ + ++P DA + + E + K +KA + PK KAK+ KT +
Sbjct: 924 EKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983
Query: 422 EETSKPK 428
+E SKPK
Sbjct: 984 KEPSKPK 990
Score = 63.2 bits (152), Expect = 5e-10
Identities = 71/278 (25%), Positives = 108/278 (38%), Gaps = 29/278 (10%)
Query: 166 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESK-- 223
+KEA E+GK +E +EE+ E G +EET P +K+ K + +E+K
Sbjct: 475 EKEAKEEEGKE-----EEGGEEEEAE--GGEEETKSPPAEEAASPEKEAKSPVKEEAKSP 527
Query: 224 -EQLPPMSEDFLLDA-----------LSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPA 271
E P E+ A E+ P A S + E+AK A +
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP 587
Query: 272 STTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLG 330
+ +A +P S +K ++ + P +E K P E K EKAK+ +++
Sbjct: 588 AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAK 647
Query: 331 ERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTET- 389
+ PE PVK K E +K P +A S + P E
Sbjct: 648 SPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV----KAEAKSPEKAKSPVKEEAK 703
Query: 390 SQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKP 427
S AK K+ A S + K+ K+ AKT E+ P
Sbjct: 704 SPEKAKSPVKEEAKSPEKAKS--PVKEEAKTPEKAKSP 739
Score = 62.8 bits (151), Expect = 6e-10
Identities = 76/342 (22%), Positives = 137/342 (40%), Gaps = 33/342 (9%)
Query: 26 ERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKP 85
E + +A +++AK+ E+ E+ +T E P ++ P EK K
Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT--PEKAKSPVKEEAKSP------EKAKS 752
Query: 86 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEP 145
+++ +D S + ++ KE+ P +K E A +PV E V P
Sbjct: 753 PEKAKTLDVKSPEA-KTPAKEEARSPADKFPEK---AKSPVKEEV------------KSP 796
Query: 146 ATLKGTVPDDAVEALADSLGKKEADP----EDGKPVMDKVKEKAKEEDREKLGEKEETIP 201
K + +DA +A + KKE E+ KP KVKE K+ + EK +T
Sbjct: 797 EKAKSPLKEDA-KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855
Query: 202 P-DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAA 260
D + EE K+ +E KE ++ ++A E+ ++ + + + A
Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE---AEDKKKVPTPEKEAPA 912
Query: 261 AISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEK 320
+ P T+ D + K+ +K + ++ ++ K E+K K +
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Query: 321 AKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 362
AKA+ DK ++ + P + + K KPP K +ED
Sbjct: 973 AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 47.8 bits (112), Expect = 2e-05
Identities = 60/268 (22%), Positives = 101/268 (37%), Gaps = 43/268 (16%)
Query: 173 DGKPVMDKVKE--KAKEEDREKLGEK--------EETIPPDYRLEEVKDKDGKPLLPKES 222
+G P + V K K E++ K+ EK EE EEV +++ K +E
Sbjct: 424 EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEG 483
Query: 223 KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 282
KE+ E E G + S E+A A E +++P +A +P
Sbjct: 484 KEEEGGEEE--------EAEGGEEETKSPPAEEA----ASPEKEAKSPVKE-EAKSPAEA 530
Query: 283 TSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
S +K+ + P E K EKAK+ +++ + PE
Sbjct: 531 KSPEKE-------------------EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEE 571
Query: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
P K + E++K PA+ + P A S + S E +++ K++ K A
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE-AKSPVKEEAKSPA 630
Query: 403 SSSKAPKNGGKAKDSAKTTEETSKPKDD 430
K K+ AK+ E+ P+ +
Sbjct: 631 EVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
Score = 36.6 bits (83), Expect = 0.045
Identities = 34/108 (31%), Positives = 48/108 (44%), Gaps = 19/108 (17%)
Query: 24 DGERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 83
D + + E + D AKAKE K E E P + K K +PEEKP
Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPS--KPAEKKEAAPEKKDTKEEKAK-------KPEEKP 969
Query: 84 KPRSESELIDE-LSEDFDR---------SECKEKPSKPTEKTEESKAA 121
K ++++ D+ LS++ + S +K SKP EK E KAA
Sbjct: 970 KTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 57.0 bits (136), Expect = 3e-08
Identities = 85/367 (23%), Positives = 145/367 (39%), Gaps = 51/367 (13%)
Query: 65 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPA 124
+PA +G P E P+ ES+ + + + SE K+ P K + K + AP
Sbjct: 524 QPAAPPEG----PRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPH 579
Query: 125 PVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS------LGKKEAD--PEDGKP 176
P + C+ S Q PP+ T+ P V+A A + G++E P +
Sbjct: 580 P-GKRSCQKS--PAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRD 636
Query: 177 VMDKVKEKAKEEDREKL---GEKEETIPPDYRLEEVKDKDGKPLL------PKESKEQLP 227
K K K K + R + E + +PP E+ K K P P+ +K+ +
Sbjct: 637 QTSKDKPKVKTKGRPRAAASNEPKPAVPPS--SEKKKHKSSLPAPSKALSGPEPAKDNVE 694
Query: 228 PMS-EDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQ----TPASTTQAGAPPRD 282
+ E F L L+E P + S + + A + E + P T+ +P RD
Sbjct: 695 DRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRD 754
Query: 283 TSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
T + L + K++ L R P P K + KAE D P +H
Sbjct: 755 TPPPQSL---MVKITLDLLSRIPQP------PGKGSRQRKAE--------DKQPPAGKKH 797
Query: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
+ D K K+ ++++ D++ L ++ S S++ +S + K K +
Sbjct: 798 SSEKRSSDSSSKLAKKRKGEAERDCDNKK--IRLEKEIKS-QSSSSSSSHKESSKTKPSR 854
Query: 403 SSSKAPK 409
SS++ K
Sbjct: 855 PSSQSSK 861
Score = 36.6 bits (83), Expect = 0.045
Identities = 42/194 (21%), Positives = 75/194 (38%), Gaps = 17/194 (8%)
Query: 28 RGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPAT-DKDGKPLLPEPEEKPKPR 86
+G+R+ + K+ EK D + ++ R A D D K + E E K +
Sbjct: 779 KGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSS 838
Query: 87 SESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPA 146
S S E S K KPS+P+ ++ + + P PVS + + + +++ + E
Sbjct: 839 SSSSSHKESS--------KTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREAD 890
Query: 147 TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRL 206
T P A K + P +V+ K E G +T P + +
Sbjct: 891 TCGQDPPKSASST-------KSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANP-FPV 942
Query: 207 EEVKDKDGKPLLPK 220
+ + + KP P+
Sbjct: 943 PSLPNGNSKPGKPQ 956
Score = 34.7 bits (78), Expect = 0.17
Identities = 45/202 (22%), Positives = 69/202 (34%), Gaps = 42/202 (20%)
Query: 246 QNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPR-----------------DTSSDKD 288
Q SS+ +D +L+ + QTP + APP ++ S D
Sbjct: 417 QGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSD 476
Query: 289 LDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNG 348
D + D S+S D +EN+P+E E PP DN
Sbjct: 477 SDSSSDSESESSSS---DSEENEPLETPAPEPE---------------PPTTNKWQLDNW 518
Query: 349 QDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAP 408
K +P + P S D + TSQ ++ K SSSKAP
Sbjct: 519 LTKVSQPAAPPEGPRSTEPPRRHPESKGSSD-------SATSQEHSESKDPPPKSSSKAP 571
Query: 409 KNGGKAKDSAKTTEETSKPKDD 430
+ +A K + + S + +
Sbjct: 572 RAPPEAPHPGKRSCQKSPAQQE 593
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 56.6 bits (135), Expect = 4e-08
Identities = 79/323 (24%), Positives = 122/323 (37%), Gaps = 42/323 (13%)
Query: 24 DGERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 83
+GE E + K EEK E+ +E + KP K P P E+
Sbjct: 568 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 627
Query: 84 KPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAPVSEAVCRTSMCSIQSAP 142
P +S + ++ +S +EK P K+ E K +P S
Sbjct: 628 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV---------------SKS 672
Query: 143 PEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETI 200
P K VP VE +GK E E+ K +VKE KEE EK EK + +
Sbjct: 673 PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKEAPKEEKVEKKEEKPKDV 728
Query: 201 PPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSEDFLLDAL-----SEDFSG 244
P + E VK+ K K L KE+KE+ P+ ++ + SE+
Sbjct: 729 PEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGS 788
Query: 245 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQ 304
+ A + ED + + E + T + G+ + + + LD LS + ++
Sbjct: 789 DKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGSGREEEKG--VVTNGLD-LSPADEKKG 844
Query: 305 PDPDENKPMEDKVKEKAKAEHRD 327
D E K + K EK +E D
Sbjct: 845 GDKSEEKVVVTKTVEKITSEGGD 867
Score = 51.6 bits (122), Expect = 1e-06
Identities = 78/378 (20%), Positives = 149/378 (39%), Gaps = 36/378 (9%)
Query: 68 TDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKT-----EESKAAA 122
+ K KP + P+ K + + E+I+E + ++SE +E + TE+ EE K AA
Sbjct: 433 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 492
Query: 123 PAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE--ALADSLGKKEADPEDGKPVMDK 180
E + + +P +K T P+ E + G++E + ED D+
Sbjct: 493 EEKEEEPEAEEEEVAAKKSP-----VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 547
Query: 181 VKEKAKEED---REKLGEKEE-TIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 236
+E E++ ++ GE+EE + EE + K+ K + E K + E+ + D
Sbjct: 548 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV---EEKSEEVATKEELVAD 604
Query: 237 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKL 296
A E P+ A S + + V ++P P+ +K
Sbjct: 605 AKVEK---PEKAKS-PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 660
Query: 297 SDSLGQRQPDPDENKPMEDKVK--------EKAKAEHRDKLGERDDTIPPEYRHLLDDNG 348
+ G+ P P+E+K K E+AK++ GE+ + E + +
Sbjct: 661 VEEKGK---SPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK 717
Query: 349 QDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAP 408
+K + P K KK A+ +A++ + S + K++ K +
Sbjct: 718 VEKKEEKP--KDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 775
Query: 409 KNGGKAKDSAKTTEETSK 426
K GG+ + +++ +K
Sbjct: 776 KAGGEGGSEEEGSDKGAK 793
Score = 46.6 bits (109), Expect = 4e-05
Identities = 74/313 (23%), Positives = 114/313 (36%), Gaps = 42/313 (13%)
Query: 24 DGERRGAREAVRIFQDQ--AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEE 81
+ E+ EA+ ++ KEEK E E +E +E A K PE +E
Sbjct: 463 EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 522
Query: 82 KPKPRSESELIDELSEDFDRSECKEKPSKPTEK----------TEESKAAAPAPVSEAVC 131
+ + E E +E E+ + ++ + +EK EE + A A EA
Sbjct: 523 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 582
Query: 132 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDRE 191
+ ++ E AT + V D VE +K P PV +K K + E
Sbjct: 583 KEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPKSPVEEKGKSPVPKSPVE 636
Query: 192 KLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSL 251
EK ++ P +EE K K P P E K + P + E P S +
Sbjct: 637 ---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK-----SPVEEKAKSPVPKSPV 687
Query: 252 KFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENK 311
E+AK A + + + AP + K+ ++ D E K
Sbjct: 688 --EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE-------------EKPKDVPEKK 732
Query: 312 PMEDKVKEKAKAE 324
E VKE+A AE
Sbjct: 733 KAESPVKEEAVAE 745
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 56.6 bits (135), Expect = 4e-08
Identities = 79/323 (24%), Positives = 122/323 (37%), Gaps = 42/323 (13%)
Query: 24 DGERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 83
+GE E + K EEK E+ +E + KP K P P E+
Sbjct: 192 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 251
Query: 84 KPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAPVSEAVCRTSMCSIQSAP 142
P +S + ++ +S +EK P K+ E K +P S
Sbjct: 252 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV---------------SKS 296
Query: 143 PEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETI 200
P K VP VE +GK E E+ K +VKE KEE EK EK + +
Sbjct: 297 PVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKEAPKEEKVEKKEEKPKDV 352
Query: 201 PPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSEDFLLDAL-----SEDFSG 244
P + E VK+ K K L KE+KE+ P+ ++ + SE+
Sbjct: 353 PEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGS 412
Query: 245 PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQ 304
+ A + ED + + E + T + G+ + + + LD LS + ++
Sbjct: 413 DKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGSGREEEKG--VVTNGLD-LSPADEKKG 468
Query: 305 PDPDENKPMEDKVKEKAKAEHRD 327
D E K + K EK +E D
Sbjct: 469 GDKSEEKVVVTKTVEKITSEGGD 491
Score = 51.6 bits (122), Expect = 1e-06
Identities = 78/378 (20%), Positives = 149/378 (39%), Gaps = 36/378 (9%)
Query: 68 TDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKT-----EESKAAA 122
+ K KP + P+ K + + E+I+E + ++SE +E + TE+ EE K AA
Sbjct: 57 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 116
Query: 123 PAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE--ALADSLGKKEADPEDGKPVMDK 180
E + + +P +K T P+ E + G++E + ED D+
Sbjct: 117 EEKEEEPEAEEEEVAAKKSP-----VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 171
Query: 181 VKEKAKEED---REKLGEKEE-TIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLD 236
+E E++ ++ GE+EE + EE + K+ K + E K + E+ + D
Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV---EEKSEEVATKEELVAD 228
Query: 237 ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKL 296
A E P+ A S + + V ++P P+ +K
Sbjct: 229 AKVEK---PEKAKS-PVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 284
Query: 297 SDSLGQRQPDPDENKPMEDKVK--------EKAKAEHRDKLGERDDTIPPEYRHLLDDNG 348
+ G+ P P+E+K K E+AK++ GE+ + E + +
Sbjct: 285 VEEKGK---SPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK 341
Query: 349 QDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAP 408
+K + P K KK A+ +A++ + S + K++ K +
Sbjct: 342 VEKKEEKP--KDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 399
Query: 409 KNGGKAKDSAKTTEETSK 426
K GG+ + +++ +K
Sbjct: 400 KAGGEGGSEEEGSDKGAK 417
Score = 46.6 bits (109), Expect = 4e-05
Identities = 74/313 (23%), Positives = 114/313 (36%), Gaps = 42/313 (13%)
Query: 24 DGERRGAREAVRIFQDQ--AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEE 81
+ E+ EA+ ++ KEEK E E +E +E A K PE +E
Sbjct: 87 EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 146
Query: 82 KPKPRSESELIDELSEDFDRSECKEKPSKPTEK----------TEESKAAAPAPVSEAVC 131
+ + E E +E E+ + ++ + +EK EE + A A EA
Sbjct: 147 EEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 206
Query: 132 RTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDRE 191
+ ++ E AT + V D VE +K P PV +K K + E
Sbjct: 207 KEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPKSPVEEKGKSPVPKSPVE 260
Query: 192 KLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSL 251
EK ++ P +EE K K P P E K + P + E P S +
Sbjct: 261 ---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK-----SPVEEKAKSPVPKSPV 311
Query: 252 KFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENK 311
E+AK A + + + AP + K+ ++ D E K
Sbjct: 312 --EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE-------------EKPKDVPEKK 356
Query: 312 PMEDKVKEKAKAE 324
E VKE+A AE
Sbjct: 357 KAESPVKEEAVAE 369
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 55.8 bits (133), Expect = 7e-08
Identities = 86/410 (20%), Positives = 165/410 (40%), Gaps = 79/410 (19%)
Query: 26 ERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKP 85
E++ E ++ ++ K + E+ + E+ + P + +L P + K PE ++
Sbjct: 1210 EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLP----EAKTSAPEEQKHDLL 1265
Query: 86 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEP 145
+S+ ++ +E E + ++ +P K E + P + + +T+ +I+ P P
Sbjct: 1266 KSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK-TIKEQPQPP 1324
Query: 146 ATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYR 205
T K D VE GK++ + ED K ++ + G + I
Sbjct: 1325 CTAK----PDQVEP-----GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSS-- 1373
Query: 206 LEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEV 265
L E+ L+P + K+ L + +D + S++ S P + S L AKL + + +
Sbjct: 1374 LGEIPS-----LIPTDEKDILKGLKKD----SFSQE-SSPSSPSDL----AKLESTVLSI 1419
Query: 266 VSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKA-- 323
+ + AST L+D +++ P E P + K +EK ++
Sbjct: 1420 L-EAQAST----------------------LADEKSEKKTQPHEVSPEQPKDQEKTQSLS 1456
Query: 324 ----------EHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPI 373
E ++ ER DT D+ QD P S+D K+ ++ D I
Sbjct: 1457 ETLEITISEEEIKESQEERKDTFK-------KDSQQDIP------SSKDHKEKSEFVDDI 1503
Query: 374 DALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 423
DS ++E S+N+ + K+ S + + K +DS + EE
Sbjct: 1504 TTRREPYDSVEESSE-SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEE 1552
Score = 45.8 bits (107), Expect = 7e-05
Identities = 73/324 (22%), Positives = 131/324 (40%), Gaps = 41/324 (12%)
Query: 113 EKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPE 172
++ +E K A + E V T S++ PP T + + A +L +K+ PE
Sbjct: 1159 KQEQEVKTEAEKVILEKVKET--LSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE 1216
Query: 173 DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 232
+ K + ++ EK + E+++ L E+++ P D K LLP E+K P +
Sbjct: 1217 EKKLIPEE--EKIRSEEKKPLLEEKKPTPED-----------KKLLP-EAKTSAPEEQKH 1262
Query: 233 FLLDALSEDFSGPQNASSLKFEDAKLAAAIS-EVVSQTPASTTQAGAPPRDTSSDKDLDD 291
LL S ++ + KL ++ + V + T+ P T +D
Sbjct: 1263 DLL------------KSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKED 1310
Query: 292 ALDKLSDSLGQRQPDPDENKPMEDKVKE-KAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 350
DK + ++ ++ P KP D+V+ K K E D + + P+ L D G
Sbjct: 1311 --DKTTKTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366
Query: 351 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK-----KAASSS 405
+ S P D++D + L D S S+ + + AK + +A +S+
Sbjct: 1367 SDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426
Query: 406 KAPKNGGKAKDSAKTTEETSKPKD 429
A + K + + E +PKD
Sbjct: 1427 LADEKSEKKTQPHEVSPE--QPKD 1448
Score = 42.0 bits (97), Expect = 0.001
Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 32/247 (12%)
Query: 205 RLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISE 264
+L +++ P PK S +P S S+ + P +K ++ ++ +
Sbjct: 1118 QLGDIRKMPPAPSGPKASPMPVPTESS-------SQKTAVPPQVKLVKKQEQEVKTEAEK 1170
Query: 265 VVSQTPAST-TQAGAPPRDTSSDKDLDDALDK-LSDSLGQRQPDPDENK--PMEDKVKEK 320
V+ + T + PP T+ K + L+K + +L +++P P+E K P E+K++ +
Sbjct: 1171 VILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSE 1230
Query: 321 AK----------AEHRDKLGERDDTIPPEYRH-LLDDNGQDKPVK----PPTKKSEDSKK 365
K E + L E + P E +H LL Q K K ++ K+
Sbjct: 1231 EKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQ 1290
Query: 366 PADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAK----DSAKTT 421
P + + SG S P + + T K++ + ++ GK K D T
Sbjct: 1291 PQTKMEGLP--SGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT 1348
Query: 422 EETSKPK 428
+ +PK
Sbjct: 1349 SSSQQPK 1355
Score = 37.4 bits (85), Expect = 0.026
Identities = 96/490 (19%), Positives = 165/490 (33%), Gaps = 93/490 (18%)
Query: 26 ERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKP 85
E +G ++ + + + K + D + +P P +P P++ PKP
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898
Query: 86 RSESELIDELSEDFDRSECKEKPSKPTEKTEE-----------------SKAAAPAPVSE 128
+ +S L+ K +P+ P E S A P P S+
Sbjct: 899 QEQSRRFS-LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ 957
Query: 129 AVCRTSMCSIQSAPPEPATLKGTVPD--DAVEALADSLGKKEADPEDGKPVMDKVKEKAK 186
+ M AP +P T +G A A A S+ K+ E P +K++ KA+
Sbjct: 958 SGPGAPMKQAP-APSQPPTSQGPPKSTGQAPPAPAKSIPVKK---ETKAPAAEKLEPKAE 1013
Query: 187 EEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--------------------------- 219
+ K E E+ PP + + + K +LP
Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDP 1073
Query: 220 ------KESKEQ------------LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAA 261
E K Q L + E L+ ++ Q K A
Sbjct: 1074 PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPK 1133
Query: 262 ISEVVSQTPASTTQAGAPPRDTSSDKDLDDA--------LDKLSDSLGQRQPDP---DEN 310
S + T +S+ + PP+ K + L+K+ ++L + P +
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 311 KPMEDKV-KEKAKA-EHRDKLGERDDTIPPEYRHLLDDN----GQDKPVKPPTKKSEDSK 364
K E K+ K+KA A + + L E IP E + ++ + KP K ++K
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK 1253
Query: 365 KPADDQDPIDALSGDLDSCPSTTE------TSQNTAKDKCKKAASSSKAPKNGGKAKD-S 417
A ++ D L + E T Q + + K S P++ K D +
Sbjct: 1254 TSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKT 1313
Query: 418 AKTTEETSKP 427
KT +E +P
Sbjct: 1314 TKTIKEQPQP 1323
Score = 36.2 bits (82), Expect = 0.059
Identities = 73/407 (17%), Positives = 147/407 (36%), Gaps = 47/407 (11%)
Query: 38 QDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSE 97
Q++ ++ E LE ++E S+ K KD + +P ++ + +SE +D+++
Sbjct: 1449 QEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDH---KEKSEFVDDITT 1505
Query: 98 DFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDD-- 155
+P + EES + +PV + RTS+ S S + +G+ ++
Sbjct: 1506 R----------REPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDF 1555
Query: 156 -AVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDG 214
+ + S + + ED + + +++KE + + +K KEET G
Sbjct: 1556 IRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQK---KEET-------------KG 1599
Query: 215 KPLLPKESKEQLPPMSEDFLLDAL-------SEDFSGPQNASSLKFEDAKLAAAISEVVS 267
K + +L S + + ED + LK+ + K + VV+
Sbjct: 1600 KGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVT 1659
Query: 268 QTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 327
T +DK ++ K + +P+ E + + D +++++ E
Sbjct: 1660 GGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPEL-EMESLTDSPEDRSRGEGSS 1718
Query: 328 KLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDAL------SGDLD 381
L T P + +D P KK E ++ P L S + +
Sbjct: 1719 SLHASSFT-PGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEE 1777
Query: 382 SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 428
E + K + + + K K KD + +PK
Sbjct: 1778 ELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPK 1824
Score = 34.7 bits (78), Expect = 0.17
Identities = 68/301 (22%), Positives = 108/301 (35%), Gaps = 35/301 (11%)
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKK 167
PS P K + AP + AV ++S Q++P + A K + L+ + K
Sbjct: 654 PSSPQPKLK----TAPVTTTSAVSKSSPQPQQTSPKKDAAPK--------QDLSKAPEPK 701
Query: 168 EADPEDGKPVMD-----KVKEKAKEEDREKLGE-KEETIPPDYRLEEVKD-KDGKPLLPK 220
+ P +P + K K+ + + K KE ++P + V D K +P + K
Sbjct: 702 KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761
Query: 221 ESKEQLPPMSEDFLLDALSEDFSGPQNASS---LKFEDAKLAAAISEVVSQTPASTTQAG 277
+ + + S D S + LK + AK + + + S +
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV--SPFDSK 819
Query: 278 APPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
A PR S K + S+S GQ+Q DP + K K + K + K + P
Sbjct: 820 AIPRPASDSKIISHP-GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP 878
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCP-STTETSQNTAKD 396
P R GQ P + S KP + G + P S T Q T
Sbjct: 879 PGPR---PTAGQTVPT------PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTG 929
Query: 397 K 397
K
Sbjct: 930 K 930
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 55.8 bits (133), Expect = 7e-08
Identities = 86/410 (20%), Positives = 165/410 (40%), Gaps = 79/410 (19%)
Query: 26 ERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKP 85
E++ E ++ ++ K + E+ + E+ + P + +L P + K PE ++
Sbjct: 1210 EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLP----EAKTSAPEEQKHDLL 1265
Query: 86 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEP 145
+S+ ++ +E E + ++ +P K E + P + + +T+ +I+ P P
Sbjct: 1266 KSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK-TIKEQPQPP 1324
Query: 146 ATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYR 205
T K D VE GK++ + ED K ++ + G + I
Sbjct: 1325 CTAK----PDQVEP-----GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSS-- 1373
Query: 206 LEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEV 265
L E+ L+P + K+ L + +D + S++ S P + S L AKL + + +
Sbjct: 1374 LGEIPS-----LIPTDEKDILKGLKKD----SFSQE-SSPSSPSDL----AKLESTVLSI 1419
Query: 266 VSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKA-- 323
+ + AST L+D +++ P E P + K +EK ++
Sbjct: 1420 L-EAQAST----------------------LADEKSEKKTQPHEVSPEQPKDQEKTQSLS 1456
Query: 324 ----------EHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPI 373
E ++ ER DT D+ QD P S+D K+ ++ D I
Sbjct: 1457 ETLEITISEEEIKESQEERKDTFK-------KDSQQDIP------SSKDHKEKSEFVDDI 1503
Query: 374 DALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEE 423
DS ++E S+N+ + K+ S + + K +DS + EE
Sbjct: 1504 TTRREPYDSVEESSE-SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEE 1552
Score = 45.8 bits (107), Expect = 7e-05
Identities = 73/324 (22%), Positives = 131/324 (40%), Gaps = 41/324 (12%)
Query: 113 EKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPE 172
++ +E K A + E V T S++ PP T + + A +L +K+ PE
Sbjct: 1159 KQEQEVKTEAEKVILEKVKET--LSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE 1216
Query: 173 DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 232
+ K + ++ EK + E+++ L E+++ P D K LLP E+K P +
Sbjct: 1217 EKKLIPEE--EKIRSEEKKPLLEEKKPTPED-----------KKLLP-EAKTSAPEEQKH 1262
Query: 233 FLLDALSEDFSGPQNASSLKFEDAKLAAAIS-EVVSQTPASTTQAGAPPRDTSSDKDLDD 291
LL S ++ + KL ++ + V + T+ P T +D
Sbjct: 1263 DLL------------KSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKED 1310
Query: 292 ALDKLSDSLGQRQPDPDENKPMEDKVKE-KAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 350
DK + ++ ++ P KP D+V+ K K E D + + P+ L D G
Sbjct: 1311 --DKTTKTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYS 1366
Query: 351 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK-----KAASSS 405
+ S P D++D + L D S S+ + + AK + +A +S+
Sbjct: 1367 SDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQAST 1426
Query: 406 KAPKNGGKAKDSAKTTEETSKPKD 429
A + K + + E +PKD
Sbjct: 1427 LADEKSEKKTQPHEVSPE--QPKD 1448
Score = 42.0 bits (97), Expect = 0.001
Identities = 53/247 (21%), Positives = 99/247 (40%), Gaps = 32/247 (12%)
Query: 205 RLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISE 264
+L +++ P PK S +P S S+ + P +K ++ ++ +
Sbjct: 1118 QLGDIRKMPPAPSGPKASPMPVPTESS-------SQKTAVPPQVKLVKKQEQEVKTEAEK 1170
Query: 265 VVSQTPAST-TQAGAPPRDTSSDKDLDDALDK-LSDSLGQRQPDPDENK--PMEDKVKEK 320
V+ + T + PP T+ K + L+K + +L +++P P+E K P E+K++ +
Sbjct: 1171 VILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSE 1230
Query: 321 AK----------AEHRDKLGERDDTIPPEYRH-LLDDNGQDKPVK----PPTKKSEDSKK 365
K E + L E + P E +H LL Q K K ++ K+
Sbjct: 1231 EKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQ 1290
Query: 366 PADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAK----DSAKTT 421
P + + SG S P + + T K++ + ++ GK K D T
Sbjct: 1291 PQTKMEGLP--SGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT 1348
Query: 422 EETSKPK 428
+ +PK
Sbjct: 1349 SSSQQPK 1355
Score = 37.4 bits (85), Expect = 0.026
Identities = 96/490 (19%), Positives = 165/490 (33%), Gaps = 93/490 (18%)
Query: 26 ERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKP 85
E +G ++ + + + K + D + +P P +P P++ PKP
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898
Query: 86 RSESELIDELSEDFDRSECKEKPSKPTEKTEE-----------------SKAAAPAPVSE 128
+ +S L+ K +P+ P E S A P P S+
Sbjct: 899 QEQSRRFS-LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ 957
Query: 129 AVCRTSMCSIQSAPPEPATLKGTVPD--DAVEALADSLGKKEADPEDGKPVMDKVKEKAK 186
+ M AP +P T +G A A A S+ K+ E P +K++ KA+
Sbjct: 958 SGPGAPMKQAP-APSQPPTSQGPPKSTGQAPPAPAKSIPVKK---ETKAPAAEKLEPKAE 1013
Query: 187 EEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--------------------------- 219
+ K E E+ PP + + + K +LP
Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDP 1073
Query: 220 ------KESKEQ------------LPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAA 261
E K Q L + E L+ ++ Q K A
Sbjct: 1074 PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPK 1133
Query: 262 ISEVVSQTPASTTQAGAPPRDTSSDKDLDDA--------LDKLSDSLGQRQPDP---DEN 310
S + T +S+ + PP+ K + L+K+ ++L + P +
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 311 KPMEDKV-KEKAKA-EHRDKLGERDDTIPPEYRHLLDDN----GQDKPVKPPTKKSEDSK 364
K E K+ K+KA A + + L E IP E + ++ + KP K ++K
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAK 1253
Query: 365 KPADDQDPIDALSGDLDSCPSTTE------TSQNTAKDKCKKAASSSKAPKNGGKAKD-S 417
A ++ D L + E T Q + + K S P++ K D +
Sbjct: 1254 TSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKT 1313
Query: 418 AKTTEETSKP 427
KT +E +P
Sbjct: 1314 TKTIKEQPQP 1323
Score = 36.2 bits (82), Expect = 0.059
Identities = 73/407 (17%), Positives = 147/407 (36%), Gaps = 47/407 (11%)
Query: 38 QDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSE 97
Q++ ++ E LE ++E S+ K KD + +P ++ + +SE +D+++
Sbjct: 1449 QEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDH---KEKSEFVDDITT 1505
Query: 98 DFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDD-- 155
+P + EES + +PV + RTS+ S S + +G+ ++
Sbjct: 1506 R----------REPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDF 1555
Query: 156 -AVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDG 214
+ + S + + ED + + +++KE + + +K KEET G
Sbjct: 1556 IRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQK---KEET-------------KG 1599
Query: 215 KPLLPKESKEQLPPMSEDFLLDAL-------SEDFSGPQNASSLKFEDAKLAAAISEVVS 267
K + +L S + + ED + LK+ + K + VV+
Sbjct: 1600 KGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVT 1659
Query: 268 QTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 327
T +DK ++ K + +P+ E + + D +++++ E
Sbjct: 1660 GGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPEL-EMESLTDSPEDRSRGEGSS 1718
Query: 328 KLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDAL------SGDLD 381
L T P + +D P KK E ++ P L S + +
Sbjct: 1719 SLHASSFT-PGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEE 1777
Query: 382 SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPK 428
E + K + + + K K KD + +PK
Sbjct: 1778 ELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPK 1824
Score = 34.7 bits (78), Expect = 0.17
Identities = 68/301 (22%), Positives = 108/301 (35%), Gaps = 35/301 (11%)
Query: 108 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKK 167
PS P K + AP + AV ++S Q++P + A K + L+ + K
Sbjct: 654 PSSPQPKLK----TAPVTTTSAVSKSSPQPQQTSPKKDAAPK--------QDLSKAPEPK 701
Query: 168 EADPEDGKPVMD-----KVKEKAKEEDREKLGE-KEETIPPDYRLEEVKD-KDGKPLLPK 220
+ P +P + K K+ + + K KE ++P + V D K +P + K
Sbjct: 702 KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761
Query: 221 ESKEQLPPMSEDFLLDALSEDFSGPQNASS---LKFEDAKLAAAISEVVSQTPASTTQAG 277
+ + + S D S + LK + AK + + + S +
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV--SPFDSK 819
Query: 278 APPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
A PR S K + S+S GQ+Q DP + K K + K + K + P
Sbjct: 820 AIPRPASDSKIISHP-GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP 878
Query: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCP-STTETSQNTAKD 396
P R GQ P + S KP + G + P S T Q T
Sbjct: 879 PGPR---PTAGQTVPT------PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTG 929
Query: 397 K 397
K
Sbjct: 930 K 930
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 55.1 bits (131), Expect = 1e-07
Identities = 74/366 (20%), Positives = 144/366 (39%), Gaps = 29/366 (7%)
Query: 70 KDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEA 129
KD E E P SE+E +++ D + E ++ P +E E A +E
Sbjct: 91 KDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENED 150
Query: 130 VCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEED 189
V + PA+ D +E L S + KP + +++E
Sbjct: 151 VGK-----------HPAS------DSEIEELQKSPASDSETEDALKPQIS--DSESEEPP 191
Query: 190 REKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNAS 249
R + + E PP R+ + + ++ +S+ + PP + D+ +E+ P+ +
Sbjct: 192 RHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQ--ASDSENEELPKPRISD 249
Query: 250 SLKFEDAKLAAAIS--EVVSQTPASTTQAGAPPRDTSSDKDLDD-ALDKLSDSLGQ-RQP 305
S + + A+ S E + + S +++ PPR+ +SD + ++ ++SDS + Q
Sbjct: 250 SESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQK 309
Query: 306 DPDENKPMEDKVKEKAKAE---HRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 362
P + ED + K K E D+ + +DT D + K + E+
Sbjct: 310 GPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEE 369
Query: 363 SKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTE 422
KK D D D G+ + + ++D+ K +A S+ + + A + +
Sbjct: 370 HKKQKMDSDE-DEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDK 428
Query: 423 ETSKPK 428
+ K
Sbjct: 429 SGKREK 434
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 55.1 bits (131), Expect = 1e-07
Identities = 87/437 (19%), Positives = 152/437 (34%), Gaps = 64/437 (14%)
Query: 42 KAKEEKLEKCGEDDETIPSEYRLKPA----------TDKDGKPLLPEPEEKPKPRSESEL 91
K K+ D IPS K TD G P+ P +S+
Sbjct: 480 KVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSG----PKETSSATPGRDSKT 535
Query: 92 IDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGT 151
I + SE + S T + P +A ++ P L +
Sbjct: 536 IQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASS 595
Query: 152 VPDDAVEALADSLGK---KEADPEDGKPVMDKVKEKAKEEDREKLGE------------K 196
+P +A K K+ +P +K K K+ + +K E +
Sbjct: 596 MPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDE 655
Query: 197 EETIPPDYRLEEVKDKDGKPLLPKESKEQ--------LPPMSEDFLLDALSEDFSGPQNA 248
E++PP + + + + P+ P +E+ PM E LL LSE P +
Sbjct: 656 SESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSE----PDDR 711
Query: 249 SSL--KFEDAKLAAAISEVVSQT-PASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQP 305
L K + L + +T P + P + T + A +K+S+ ++
Sbjct: 712 YPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQK--QASEKVSNKGKRKHK 769
Query: 306 DPDENKPMEDKVKEKAKAEHRDKLGERDDT-------IPPEYRHLLDDNGQDKPVKPPTK 358
+ D+N+ E K K K E ++ G + + + + LL P K P
Sbjct: 770 NEDDNRASESK---KPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKT 826
Query: 359 KSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSS-------KAPKNG 411
+ K+ + + S +++ S +T+K K + +SS KAP +
Sbjct: 827 EHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSS 886
Query: 412 GKAKDSAKTTEETSKPK 428
SA T ++SKP+
Sbjct: 887 SNCPPSAPTL-DSSKPR 902
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 53.5 bits (127), Expect = 4e-07
Identities = 92/419 (21%), Positives = 156/419 (37%), Gaps = 86/419 (20%)
Query: 41 AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL----LPEPEEKPKPRSESELIDELS 96
AK ++K +D + E P K P LP P + SES +E S
Sbjct: 75 AKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLP-PGKAAAKASESSSSEESS 133
Query: 97 EDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDA 156
+D D + K++P + K ++KAA APP+ A + D +
Sbjct: 134 DDDDEEDQKKQPVQKGVK-PQAKAA------------------KAPPKKAKSSDSDSDSS 174
Query: 157 VEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKP 216
E + P++ KP + V KA+ + PP K +GK
Sbjct: 175 SE---------DEPPKNQKPKITPVTVKAQTK-----------APPKPARAAPKIANGKA 214
Query: 217 LLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQA 276
S + S D S + A++ + +++ + + T+
Sbjct: 215 ASSSSSSS-----------SSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRK 263
Query: 277 GAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDK---VKEKAKAEHRDKLGERD 333
+ D+SSD++ ++ + + G P + P K + KA + + E
Sbjct: 264 SSSSEDSSSDEE-EEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESS 322
Query: 334 DTIPPEYRHLLDDNGQDKPVKPPTK--------KSEDSKKPAD-DQDPIDALSGDLDSCP 384
+ E D+ ++ KPPTK K +KK A+ D D+ S + D P
Sbjct: 323 EDSSDE-----SDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAP 377
Query: 385 S----TTETSQN----TAKDKCKKAASSSKAPKNGG-----KAKDSAKTTEETSKPKDD 430
S TT+ S N T K K A++ K P GG + DS+ + EE+S +++
Sbjct: 378 SKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEE 436
Score = 44.3 bits (103), Expect = 2e-04
Identities = 65/304 (21%), Positives = 103/304 (33%), Gaps = 51/304 (16%)
Query: 176 PVMDKVKEKAKEEDREKLGEKEETI--PPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDF 233
PV K K+KA D E E+EE + PP + + G P +K SE+
Sbjct: 73 PVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEES 132
Query: 234 LLDALSED----------------FSGPQNASSLKFEDAKLAAAISEVVSQTPAST---- 273
D ED P + D+ ++ +Q P T
Sbjct: 133 SDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTV 192
Query: 274 -TQAGAPPRDTSSDKDLDD---ALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKL 329
Q APP+ + + + A S S D +E K K K + K
Sbjct: 193 KAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKA 252
Query: 330 GERDDTIPPEYRHLLDDNGQD------KPVK--------------PPTKKS---EDSKKP 366
+ T P +D+ D KP+K PP KKS + KK
Sbjct: 253 PVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKA 312
Query: 367 ADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSK 426
+ Q P+++ D S++E + A++ P KA +S+ + ++
Sbjct: 313 VEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAK--KAAESSSDSSDSDS 370
Query: 427 PKDD 430
+DD
Sbjct: 371 SEDD 374
Score = 40.8 bits (94), Expect = 0.002
Identities = 76/314 (24%), Positives = 119/314 (37%), Gaps = 51/314 (16%)
Query: 53 EDDETIPSEYRLKPATDKDGK------PLLPEPEEK-----PKPRSESELIDELSEDFDR 101
ED + E + KP +K G P P P++ PK E + E SED
Sbjct: 268 EDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSD 327
Query: 102 ---SECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS-------APPEPA-TLKG 150
S +E+ KP K SKA P ++ +S S S AP +PA T K
Sbjct: 328 ESDSSSEEE-KKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKN 386
Query: 151 TVPDDAVEALADSLGKKEADPED----GKPVMDKVKEKAKEEDREKLGEKEETIPPDYRL 206
+ AV + ++ K A P+ G+ ++ + + + E+ E+E+T +
Sbjct: 387 SSNKPAVTTKSPAV-KPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKT---KKMV 442
Query: 207 EEVKDKDGKPLLPKESKEQLPPMSEDFLLD---ALSEDFSGPQNASSLKFEDAKLAAAIS 263
K K +Q P S D D + SE+ + S++K + K+A
Sbjct: 443 ATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG-- 500
Query: 264 EVVSQTPASTTQAGA-PPRDTSSDKDLDDALDKLSDSLGQRQPDPDEN------------ 310
PAS + A +SSD ++ +KL R P N
Sbjct: 501 -AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKA 559
Query: 311 -KPMEDKVKEKAKA 323
K E++ +EK KA
Sbjct: 560 AKNSEEEEEEKKKA 573
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 53.1 bits (126), Expect = 5e-07
Identities = 92/358 (25%), Positives = 137/358 (38%), Gaps = 62/358 (17%)
Query: 41 AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKP---LLPE------PEEKPK------P 85
AK E + E+ +P E R+ P + P ++PE P +KP+ P
Sbjct: 10467 AKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVP 10526
Query: 86 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAP-VSEAVCRTSMCSIQSAPPE 144
+ E++ E + E P PT+ E KAA P V EA+ PP+
Sbjct: 10527 EAPKEVVPEKKVPVPPPKKPEVP--PTKVPEVPKAAVPEKKVPEAI-----------PPK 10573
Query: 145 PATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDY 204
P + VP+ E + + KK KP + VK E +E + EK+ +PP
Sbjct: 10574 PESPPPEVPEAPKEVVPE---KKVPAAPPKKPEVTPVK--VPEAPKEVVPEKKVPVPPPK 10628
Query: 205 RLEEVKDKDGKPLLPK----ESK--EQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKL 258
+ E K P +PK E K E +PP E E F P E+ L
Sbjct: 10629 KPEVPPTK--VPEVPKVAVPEKKVPEAIPPKPES----PPPEVFEEP--------EEVAL 10674
Query: 259 AAAISEVVSQT-PASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKV 317
+EVV + PA+ Q PP+ +K + K + + P+ + E KV
Sbjct: 10675 EEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKV 10734
Query: 318 K---EKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDP 372
K K+ E + PE + + KP PP K E KKP ++ P
Sbjct: 10735 PLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPK----KPEVPPAKVPEVPKKPVLEEKP 10788
Score = 47.4 bits (111), Expect = 3e-05
Identities = 86/439 (19%), Positives = 165/439 (37%), Gaps = 63/439 (14%)
Query: 44 KEEKLEKCGEDDETIPSEYRLKPATDK--DGKPLLPEPEEKPKPRSESELIDELSEDFDR 101
+EE E + I +E ++ A K + P +PE EKP P + + +
Sbjct: 9254 EEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPA 9313
Query: 102 SECKEKPSKPTEKTEE------SKAAAPA--------PVSEAVCRTSMCSIQSAPPE--P 145
+ E P KP + ++ + AAP PV E + + APP P
Sbjct: 9314 PKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVP 9373
Query: 146 ATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYR 205
KG V ++ + + ++E+ P P + ++ +K E+R+ + KEE +PP +
Sbjct: 9374 EVQKGVVTEEKITIVTQ---REESPP----PAVPEIPKKKVPEERKPVPRKEEEVPPPPK 9426
Query: 206 LEEVKDK---DGKPLLPKESKEQLPPMSEDFLLDALSED----------FSGPQNASSLK 252
+ + K + K +P ++ PP + + E+ F+ PQ +
Sbjct: 9427 VPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTR 9486
Query: 253 FE----------DAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKD---LDDALDKLSDS 299
E + + +IS + +A + + + +++ L +S
Sbjct: 9487 HEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKR 9546
Query: 300 LGQRQPDPDENKPMEDKVKEKAKAEHRD----KLGERDDTIPPEYRHLLDDNGQDKPVKP 355
+ + E + + +K K A+ + K+ E I PE + + K P
Sbjct: 9547 VEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKK--VPAPVPKKEKVP 9604
Query: 356 PTKKSEDSKKPADDQDPIDALSGDLDSCPS--TTETSQNTAKDKCKKAASSSKAPKNGGK 413
P K E+ KKP ++ + + P+ T Q T ++K A + +AP
Sbjct: 9605 PPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARV 9664
Query: 414 AKDSAKTTEETS----KPK 428
++ + E KPK
Sbjct: 9665 PEEPKRAVPEEKVLKLKPK 9683
Score = 41.6 bits (96), Expect = 0.001
Identities = 77/364 (21%), Positives = 134/364 (36%), Gaps = 63/364 (17%)
Query: 58 IPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPT----- 112
+P E + P K P PE KP + ++ E ++ E P KP
Sbjct: 9958 VPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKV 10017
Query: 113 -----EKTEESKAAAP----APVSEAVCRTSMCSIQSAPPE--PATLKGTVPDD------ 155
+K E A P PV E APP P K +P++
Sbjct: 10018 PVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPV 10077
Query: 156 --AVEALADSLGKKE-------ADPEDGKPVMDK---VKEKAKEEDREKLGEKEETIPPD 203
VEA + KK A P++ + + ++ +E+ E+ E L E+EE +P +
Sbjct: 10078 PKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEE 10137
Query: 204 YRLEEVKDKDGKPLLPKESKEQLP-----PMSEDF-----LLDALSEDFSGPQNASSLKF 253
EEV ++ + +P E +E P P E+F +L + P +K
Sbjct: 10138 ---EEVLPEEEE--IPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKK 10192
Query: 254 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPM 313
+ + I + PA + P+ + + L K + L P +P
Sbjct: 10193 KVTEKKVVIPKKEEAPPAKVPEV---PKKVEEKRII---LPKEEEVL----PVEVTEEPE 10242
Query: 314 EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK----KSEDSKKPADD 369
E+ + E+ E + E ++ PP ++ + P P K ++ SKK ++
Sbjct: 10243 EEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEE 10302
Query: 370 QDPI 373
+ P+
Sbjct: 10303 KVPV 10306
Score = 40.0 bits (92), Expect = 0.004
Identities = 74/388 (19%), Positives = 135/388 (34%), Gaps = 49/388 (12%)
Query: 75 LLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTS 134
LLP PEEK P E+ + + D + KP + T + E K P
Sbjct: 8968 LLPTPEEKKPPPKRIEVTKKAVKK-DAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPE 9026
Query: 135 MCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLG 194
+ + S E + T + + KK+A ++ + ++ EE ++L
Sbjct: 9027 IIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESF-----EEPYDELE 9081
Query: 195 EKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDF----LLDALSEDFSGPQNASS 250
+ T P + E D+D + + + KE EDF E + +
Sbjct: 9082 VEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWE 9141
Query: 251 LKFEDAKLAAAISEVVSQT-----PASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQ- 304
+++ ++ EV ++ PA + APP K + + ++K S + + +
Sbjct: 9142 EAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKV 9201
Query: 305 -------------PDPDENKPMEDKVKE-KAKAEHRDKL--------------GERDDTI 336
P P++++V E K A H K+ E T+
Sbjct: 9202 QVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTV 9261
Query: 337 PPEYRHLLDDN----GQDKPVKPPTKKSEDSKKPADDQ-DPIDALSGDLDSCPSTTETSQ 391
P + ++ + K V+PP K E +KPA ++ P+ P E +
Sbjct: 9262 PEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPK 9321
Query: 392 NTAKDKCKKAASSSKAPKNGGKAKDSAK 419
++ K K P K + K
Sbjct: 9322 KPVPEEKKPVPVPKKEPAAPPKVPEVPK 9349
Score = 38.5 bits (88), Expect = 0.012
Identities = 72/341 (21%), Positives = 130/341 (38%), Gaps = 46/341 (13%)
Query: 58 IPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEE 117
+P E P K P PE KP E ++ + + K P P + E
Sbjct: 10012 VPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKV-PEVPKKLIPE 10070
Query: 118 SKAAAPAPVSEAVCRTSMCSIQSAPPEPATL---------KGTVPDDAVEALADSLGKKE 168
K P P + + P P L + VP++ V + + +E
Sbjct: 10071 EKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEE 10130
Query: 169 AD--PEDGKPVMDKVKEKAKEED----REKLGEKEETIPPDYRLEEVKDK---------- 212
+ PE+ + + ++ + +EE+ E + E+EE +P + L EVK K
Sbjct: 10131 EEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEI 10190
Query: 213 -----DGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 267
+ K ++PK KE+ PP + + E L E+ L ++E
Sbjct: 10191 KKKVTEKKVVIPK--KEEAPPAKVPEVPKKVEE------KRIILPKEEEVLPVEVTEEPE 10242
Query: 268 QTPASTTQAGAPPRDTSSDKDLDD-ALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHR 326
+ P S + P + S +++++ A ++ + + ++ P+ P+ KV E A+
Sbjct: 10243 EEPISEEEI---PEEPPSIEEVEEVAPPRVPEVI--KKAVPEAPTPVPKKV-EAPPAKVS 10296
Query: 327 DKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPA 367
K+ E +P + + + P K P KK KK A
Sbjct: 10297 KKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEA 10337
Score = 38.1 bits (87), Expect = 0.016
Identities = 49/202 (24%), Positives = 76/202 (37%), Gaps = 20/202 (9%)
Query: 35 RIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPE--PEEKPKPRSESELI 92
+IFQ +A K++ EK +P + L P G+ + + PE KP+P+ E L
Sbjct: 10896 KIFQLKAIPKKKVPEK-----PQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLK 10950
Query: 93 DELSEDFDRSECKEKPSK--PTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPA---- 146
L + + E K +P K +K + P PV E T + + PEP
Sbjct: 10951 SVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT-VTKRERKIPEPTKVPE 11009
Query: 147 -----TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIP 201
L P EA ++ +PE P+ V + E KEE
Sbjct: 11010 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEP-TPIAAPVTVPVVGKKAEAKAPKEEAAK 11068
Query: 202 PDYRLEEVKDKDGKPLLPKESK 223
P ++ V K P+ + K
Sbjct: 11069 PKGPIKGVPKKTPSPIEAERRK 11090
Score = 36.6 bits (83), Expect = 0.045
Identities = 78/386 (20%), Positives = 141/386 (36%), Gaps = 62/386 (16%)
Query: 45 EEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSEC 104
E ++E+ E++E E + + + + + + + E + + E F+ E
Sbjct: 10371 EAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEV 10430
Query: 105 K--EKPSKPTEKTEESKAAAPA--PVSEAVCRTSMCSIQSAPPEPATL--KGTVPDDA-- 156
+ EKP P + E S+ P P ++ V R + P+ + K VP++
Sbjct: 10431 EVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRV 10490
Query: 157 -VEALADSLGKKEADPEDGKPVMDKVKEKAK-----EEDREKLGEKEETIPPDYRLE--- 207
+ + L KE PE PV K +A E +E + EK+ +PP + E
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPP 10550
Query: 208 -EVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFE---DAKLAAAIS 263
+V + + K+ E +PP E S P E + K+ AA
Sbjct: 10551 TKVPEVPKAAVPEKKVPEAIPPKPE-----------SPPPEVPEAPKEVVPEKKVPAAPP 10599
Query: 264 EVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKA 323
+ TP +A P++ +K + P P + + KV E K
Sbjct: 10600 KKPEVTPVKVPEA---PKEVVPEKKVP-------------VPPPKKPEVPPTKVPEVPKV 10643
Query: 324 EHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSC 383
+K + + IPP KP PP + E+ ++ A ++ P + + +
Sbjct: 10644 AVPEK--KVPEAIPP------------KPESPPPEVFEEPEEVALEEPPAEVVEEPEPAA 10689
Query: 384 PSTTETSQNTAKDKCKKAASSSKAPK 409
P + K A +K P+
Sbjct: 10690 PPQVTVPPKKPVPEKKAPAVVAKKPE 10715
Score = 34.7 bits (78), Expect = 0.17
Identities = 65/242 (26%), Positives = 92/242 (38%), Gaps = 29/242 (11%)
Query: 29 GAREAVRIFQDQAKA--KEEKLEKCGEDDETIPSEYRLKPAT-DKDGKPLLPEPEEKPKP 85
G + VR + K KEE + K E +++P +K KP +PEP PKP
Sbjct: 10927 GGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPP-PKP 10985
Query: 86 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSE------AVCRTSMCSIQ 139
E E+ + K +PT K E K A P P E A +T
Sbjct: 10986 VEEVEVPTVTKRE-------RKIPEPT-KVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPV 11037
Query: 140 SAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL-----G 194
P P TVP +A A + ++ A P+ + K E +R KL G
Sbjct: 11038 EPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGG 11097
Query: 195 EK-EETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKF 253
EK + P Y+L+ V K KE K+ + SE A+ E P A +
Sbjct: 11098 EKPPDEAPFTYQLKAVPLK-----FVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWM 11152
Query: 254 ED 255
+D
Sbjct: 11153 KD 11154
Score = 33.1 bits (74), Expect = 0.50
Identities = 83/359 (23%), Positives = 126/359 (35%), Gaps = 65/359 (18%)
Query: 32 EAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPK---PRSE 88
E V + + A+ EE E T+P + KP +K ++ + E P P
Sbjct: 10670 EEVALEEPPAEVVEEP-EPAAPPQVTVPPK---KPVPEKKAPAVVAKKPELPPVKVPEVP 10725
Query: 89 SELIDELSEDFDRSECKEKPSK-----PTEKTEESKAAAP-------APVSEAVCRTSMC 136
E++ E + E P P E E K A P A V E V + +
Sbjct: 10726 KEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPE-VPKKPVL 10784
Query: 137 SIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEK 196
+ A P P + P + E + ++E PE+ KPV A+EE+ E
Sbjct: 10785 EEKPAVPVPERAESP-PPEVYEEPEEIAPEEEIAPEEEKPV-----PVAEEEEPE----- 10833
Query: 197 EETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDA 256
+PP EE K + +P K + PP E E
Sbjct: 10834 ---VPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEP---------------------EPE 10869
Query: 257 KLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLD-DALDKLSDSLGQRQPDPDENKPMED 315
K + E P APP++ +K A+ K + P+ E P++
Sbjct: 10870 K----VIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKV 10925
Query: 316 KVKEKAKAEHRDKLGERDDTIPPE--YRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDP 372
EK + R L ER E + +L +++ K KK E KKPA + P
Sbjct: 10926 PGGEK---KVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPP 10981
Score = 31.2 bits (69), Expect = 1.9
Identities = 40/161 (24%), Positives = 59/161 (36%), Gaps = 21/161 (13%)
Query: 73 KPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCR 132
KP P P P E I +L + + EKP P EK E + P E R
Sbjct: 10878 KPRPPPPPPAPPKEDVKEKIFQLKA-IPKKKVPEKPQVP-EKVELTPLKVPG--GEKKVR 10933
Query: 133 TSMCSIQSAPPEPATLKGTV------PDDAVEALADSLGKKEADPEDGKPVMDKVKEKAK 186
+ + P E LK + + VE KK A PE P + +
Sbjct: 10934 KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPP------KPVE 10987
Query: 187 EEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLP 227
E + + ++E IP ++ E+ KP +P + E P
Sbjct: 10988 EVEVPTVTKRERKIPEPTKVPEI-----KPAIPLPAPEPKP 11023
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 50.8 bits (120), Expect = 2e-06
Identities = 76/376 (20%), Positives = 147/376 (39%), Gaps = 86/376 (22%)
Query: 38 QDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSE 97
+DQ+K KE + + ++ET+ S+ + ++P EEK + + +E D+
Sbjct: 264 KDQSKQKESQRKF---EEETVKSKVTVDTG-------VIPASEEKAETPTAAE--DDNEG 311
Query: 98 DFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAV 157
D + + K+K + EK +E K P AT+K +A+
Sbjct: 312 DKKKKDKKKKKGEKEEKEKEKKKG---------------------PSKATVKAM--QEAL 348
Query: 158 EALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPL 217
L + +++ + E+ +++++ K KEE+R + ++E + +E K+GK L
Sbjct: 349 AKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLL 408
Query: 218 LPKE----------------------SKEQLP---PMSEDFLLDALSEDFSGPQNASSLK 252
+ SK+ LP P+ ED + + + + S++
Sbjct: 409 TKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESME 468
Query: 253 FEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDA-LDKLSDSLGQRQPDPDENK 311
L AA+ + P + PP + ++D +DA LD + + E
Sbjct: 469 -----LCAAVEVMEQGVPEK--EETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGN 521
Query: 312 PMEDKVKEKAKAEHRDKLGERDDTIPPEYRH----------------LLD--DNGQDKPV 353
+ +VKE + E ++ E +D E + D D+G+
Sbjct: 522 KVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDK 581
Query: 354 KPPTKKSEDSKKPADD 369
KP + S DS+ +DD
Sbjct: 582 KPSKEMSSDSEYDSDD 597
Score = 42.4 bits (98), Expect = 8e-04
Identities = 93/454 (20%), Positives = 159/454 (35%), Gaps = 135/454 (29%)
Query: 38 QDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPE----PEEKPKPRSESELID 93
++Q +E EDD+ + +++K K + E EEK K R E +
Sbjct: 202 KNQKNKPGPNIESGNEDDD---ASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEE 258
Query: 94 ELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVP 153
+ D+S+ KE K E+T +SK G +P
Sbjct: 259 LETGKKDQSKQKESQRKFEEETVKSKVTVDT-------------------------GVIP 293
Query: 154 DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDRE--------------------KL 193
A E A++ E D E K DK K+K ++E++E KL
Sbjct: 294 --ASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKL 351
Query: 194 GEKEETIPPD-----YRLEEV--------------------KDKDGKPLLPKE------- 221
E+EE + RLEE+ K+K+ K L KE
Sbjct: 352 KEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKS 411
Query: 222 -----------------------SKEQLP---PMSEDFLLDALSEDFSGPQNASSLKFED 255
SK+ LP P+ ED + + + + S+
Sbjct: 412 QREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESM---- 467
Query: 256 AKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDA-LDKLSDSLGQRQPDPDENKPME 314
+L AA+ + P + PP + ++D +DA LD + + E +
Sbjct: 468 -ELCAAVEVMEQGVPEK--EETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVH 524
Query: 315 DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQD--- 371
+VKE + E ++ E +D E ++ G+ + ++ E+ +K +D++D
Sbjct: 525 IEVKENPEEEEEEEEEEEEDEESEEEE---EEEGESE----GSEGDEEDEKVSDEKDSGK 577
Query: 372 -----PIDALSGDLDSCPSTTETSQNTAKDKCKK 400
P +S D + T + A DK K+
Sbjct: 578 TLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKR 611
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/295 (22%), Positives = 118/295 (40%), Gaps = 37/295 (12%)
Query: 154 DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEE----DREKLGEK-EETIPPDYRLEE 208
DD ++ L + + + D + V K E +EE D++K G+K ++ D EE
Sbjct: 56 DDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE 115
Query: 209 VKDKDGKPLLPKESK-EQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 267
++DKD K + K E +D + L + G S+ K++ ++ S+ +
Sbjct: 116 LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIK 175
Query: 268 QTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQR-----QPDPDENKPMED-----KV 317
+ R SS + D++ + L GQ+ +P P+ ED K+
Sbjct: 176 ER----------SRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKI 225
Query: 318 KEKA--KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD------- 368
K A KAE +++ ++ D + R L + + K +K+ E +K +
Sbjct: 226 KTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKV 285
Query: 369 --DQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTT 421
D I A ++ + + ++ K K KK K K K K +K T
Sbjct: 286 TVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKAT 340
Score = 35.8 bits (81), Expect = 0.077
Identities = 66/258 (25%), Positives = 104/258 (40%), Gaps = 53/258 (20%)
Query: 21 KLCDGERRGAREAV----RIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLL 76
KL + E R RE R+ + +AK KEE+ + + + E K K+GK LL
Sbjct: 350 KLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGK-LL 408
Query: 77 PEPEEKPKPRSESEL-------IDELSEDFDRSECKEKP---SKPTEKTEESKAAAPAPV 126
+ + + + R+E+ L ++ S+D S K++P K +K + +
Sbjct: 409 TKSQREARARAEATLKLLQAQGVEVPSKD---SLPKKRPIYEDKKRKKIPQQLESKEVSE 465
Query: 127 SEAVCRTSMCSIQSAPPEPATLKGTVPD----------DAVEALADSLGKKEADPEDGKP 176
S +C Q P + T P+ D EA+A +E + +G
Sbjct: 466 SMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASD---EETEKVEGNK 522
Query: 177 VMDKVKEKAKEEDREK---------------LGEKE--ETIPPDYRLEEVKDKDGKPLLP 219
V +VKE +EE+ E+ GE E E D ++ + KD GK L
Sbjct: 523 VHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKD-SGKTLDK 581
Query: 220 KESKEQLPPMSEDFLLDA 237
K SKE MS D D+
Sbjct: 582 KPSKE----MSSDSEYDS 595
Score = 35.4 bits (80), Expect = 0.10
Identities = 40/166 (24%), Positives = 74/166 (44%), Gaps = 26/166 (15%)
Query: 283 TSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
T D DLD ++ + ++ +P ++K + K K+K + D L E ++ + E +
Sbjct: 13 TKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE-LSLEAQG 71
Query: 343 L-----------LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQ 391
+ ++N ++ K KK + KK + D + + L D DS S+
Sbjct: 72 IKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELE-DKDS------KSK 124
Query: 392 NTAKDKCKKAASS------SKAPKNG-GKAKDSAKTTEETSKPKDD 430
TAK K + + S +K PK GKA+ S K + + + +D+
Sbjct: 125 KTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN 170
Score = 35.0 bits (79), Expect = 0.13
Identities = 63/294 (21%), Positives = 108/294 (36%), Gaps = 37/294 (12%)
Query: 149 KGTVPDDAVEALADSLGK-KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLE 207
K + DA+ A + G KE +P+ K K K+K ++ + L E EE +
Sbjct: 14 KDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEEL---SLEAQ 70
Query: 208 EVK-DKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVV 266
+K D++ + P E+ E E+F + Q F+D SE +
Sbjct: 71 GIKADRETVAVKPTENNE------EEF---TSKDKKKKGQKGKKQSFDDND-----SEEL 116
Query: 267 SQTPASTTQAGAPPRDTSSDKDLDDALDKL-------SDSLGQRQPDPDENKPMEDKVKE 319
+ + + P + S D DD +KL + ++ +E++ K+KE
Sbjct: 117 EDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKE 176
Query: 320 KAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVK-PPTKKSEDSKKPADDQDPIDALSG 378
+++ + G+ D L GQ K K P E + D I ++
Sbjct: 177 RSRINSSGESGDESD------EFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQ 230
Query: 379 DLDSCPSTTETSQNTAKDKCKKAASSSK---APKNGGKAKDS-AKTTEETSKPK 428
++ K K +K + K+ K K+S K EET K K
Sbjct: 231 KKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSK 284
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 49.3 bits (116), Expect = 7e-06
Identities = 81/386 (20%), Positives = 136/386 (35%), Gaps = 52/386 (13%)
Query: 44 KEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSE 103
K+ KL + DDE+ P +KPA ++ ++ + + ++ E+ D+ S+D SE
Sbjct: 93 KKAKLLEINSDDES-PECCHVKPAI-QEPPIVISDDDNDDDNGNDLEVPDDNSDD---SE 147
Query: 104 CKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS 163
+ S +E +++ + AP S S P+ + VPDD + +D
Sbjct: 148 APDDNSDDSEAPDDNSDDSEAPDDN--------SDDSEAPDDNSDDSDVPDDNSDDSSDD 199
Query: 164 LGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESK 223
+D D D +K+ + D + +P D D P +
Sbjct: 200 NSDDSSD--DNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDS-----SDDSEAPDDSSDDS 252
Query: 224 EQLPPMSEDFLL-DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 282
E S+D D S+D P ++S D A+ S S+ ++ P D
Sbjct: 253 EAPDDSSDDSEAPDDSSDDSEAPDDSS-----DDSEASDDSSDDSEASDDSSDDSEAPDD 307
Query: 283 TSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH 342
S D D+ + SD D + P ED E A ++L E +
Sbjct: 308 KSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAV------ 361
Query: 343 LLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAA 402
DS A +QD L +L PS E + ++ K
Sbjct: 362 ----------------SQHDSSDDAGEQD----LGENLSKPPSDPEANPEVSERKLPTEE 401
Query: 403 SSSKAPKNGGKAKDSAKTTEETSKPK 428
+ + GK K KT E + +
Sbjct: 402 EPAPVVEQSGKRKSKTKTIVEPPRKR 427
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/193 (22%), Positives = 72/193 (37%), Gaps = 28/193 (14%)
Query: 238 LSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLS 297
+S+D + N + L+ D + S+ P + P D S D + D D
Sbjct: 123 ISDDDNDDDNGNDLEVPDD------NSDDSEAPDDNSDDSEAPDDNSDDSEAPD--DNSD 174
Query: 298 DSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPT 357
DS PD+N D + + DD+ DDN D V P
Sbjct: 175 DSEA-----PDDNSDDSDVPDDNS-----------DDSSDDNSDDSSDDNSDDSDV--PD 216
Query: 358 KKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDS 417
KS+DS P D D D D + ++S ++ + ++ S+AP + ++
Sbjct: 217 DKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDS--EAPDDSSDDSEAPDDSSDDSEA 274
Query: 418 AKTTEETSKPKDD 430
+ + S+ DD
Sbjct: 275 PDDSSDDSEASDD 287
Score = 39.3 bits (90), Expect = 0.007
Identities = 35/149 (23%), Positives = 62/149 (41%), Gaps = 15/149 (10%)
Query: 282 DTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYR 341
D SSD + DD+ D SD D ++K + V + + + DD+ P
Sbjct: 194 DDSSDDNSDDSSDDNSD-----DSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAP--- 245
Query: 342 HLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKA 401
DD+ D + P S+DS+ P D D +A D ++ ++S ++ + +
Sbjct: 246 ---DDSSDDS--EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDS--EASDDS 298
Query: 402 ASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+ S+AP + D + + S DD
Sbjct: 299 SDDSEAPDDKSDDSDVPEDKSDDSDVPDD 327
Score = 32.7 bits (73), Expect = 0.65
Identities = 43/184 (23%), Positives = 73/184 (39%), Gaps = 25/184 (13%)
Query: 223 KEQLPPMSED------FLLD--ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTT 274
K++LP + E ++L+ + S+D SG A A + T S+
Sbjct: 5 KKELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSV 64
Query: 275 QAGAPPRDTSSDKDLDDALDKLSDSLGQRQP-----DPDENKPMEDKVKEKAKAEHRDKL 329
AP R SS +D D+ + +++ + D+ P VK A E +
Sbjct: 65 ARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKP-AIQEPPIVI 123
Query: 330 GERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTET 389
+ D+ DDNG D V P S+DS+ P D+ D +A + D + +
Sbjct: 124 SDDDND---------DDNGNDLEV--PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDN 172
Query: 390 SQNT 393
S ++
Sbjct: 173 SDDS 176
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 48.5 bits (114), Expect = 1e-05
Identities = 80/418 (19%), Positives = 169/418 (40%), Gaps = 45/418 (10%)
Query: 38 QDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL---LPEP--EEKPKPRSESELI 92
+++ + +E+ E+ G+D+ E + ++G+ + PE +E+PK RS+ + +
Sbjct: 274 EEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEV 333
Query: 93 DELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSE---AVCRTSMCSIQSAPPEPATLK 149
E F RS+ + + S + +E + +P+ E + + +S P P L
Sbjct: 334 LERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRL- 392
Query: 150 GTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEV 209
+D +A +L ++ A E+ P + KE + +L +EE P + V
Sbjct: 393 ---TEDRKKASLVALPEQTASEEETPPPL-LTKEASSPPPHPQLHSEEEIEPMEGPAPPV 448
Query: 210 KDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQT 269
+ P +++E L L+ LS S P D K + +V ++
Sbjct: 449 LIQLSPPNTDADTRELLVSQHTVQLVGGLS-PLSSP--------SDTKAESPAEKVPEES 499
Query: 270 PASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKL 329
Q + D S+ KDL+ D+ + L + + K + ++ ++ E ++
Sbjct: 500 VLPLVQK-STLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKE-- 556
Query: 330 GER-DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADD------QDPIDALSGDLDS 382
G R T+ P +R + + S S+ + D P+ + D+
Sbjct: 557 GRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQ 616
Query: 383 CPS-------------TTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKP 427
+ +T S++ ++ + + A+S+S+ + G ++DS+ + ET P
Sbjct: 617 ARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDP 674
Score = 35.0 bits (79), Expect = 0.13
Identities = 28/108 (25%), Positives = 54/108 (50%), Gaps = 21/108 (19%)
Query: 20 DKLCDGERRGAREAVRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP 79
DK+ +G R +R R +++AK+KE+K EK + E P++ LL +
Sbjct: 1168 DKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAK-------------LLDDL 1214
Query: 80 EEKPK--------PRSESELIDELSEDFDRSECKEKPSKPTEKTEESK 119
K K P ++S+++ + +E +R++ +EK K E+ E+ +
Sbjct: 1215 FRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKE 1262
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 48.5 bits (114), Expect = 1e-05
Identities = 68/327 (20%), Positives = 112/327 (34%), Gaps = 54/327 (16%)
Query: 74 PLLPEPEEKP-KPRSESELIDELSEDFDRSECKEKP--SKPTEKTEESKAAAPAPVSEAV 130
PL P PEE P P E+ + E+ S E S+P E++ S +P+S
Sbjct: 448 PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPP 507
Query: 131 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 190
+ ++ +P P + + P A+E + P + P+ +E
Sbjct: 508 ESSPFSPLEESPLSPP--EESPPSPALETPL-------SPPPEASPLSPPFEESPLSPPP 558
Query: 191 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASS 250
E+L T PP P+ S+ PP S P AS
Sbjct: 559 EEL----PTSPP----------------PEASRLSPPPEESPMSPPPEESPMSPPPEASR 598
Query: 251 L--KFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPD 308
L FE++ L+ E P ++ PP D+ +++ P P+
Sbjct: 599 LFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES---------PMSPPPE 649
Query: 309 ENK----PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSK 364
++ P+ ++ + E T PP L +D P PP + S S
Sbjct: 650 VSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP 709
Query: 365 KPAD-------DQDPIDALSGDLDSCP 384
P D ++ P+ L + CP
Sbjct: 710 PPEDSLMSLPLEESPLLPLPEEPQLCP 736
Score = 35.4 bits (80), Expect = 0.10
Identities = 49/203 (24%), Positives = 75/203 (36%), Gaps = 16/203 (7%)
Query: 58 IPSEYRLKPATDKDGKPLLPEPEEKP-KPRSESELIDELSEDFDRSECKEKP---SKPTE 113
+P E +L P ++ G L P PEE PR E + +E+ S E+P + P E
Sbjct: 728 LPEEPQLCPRSE--GPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785
Query: 114 KTEESKAAAP--APVSEAVC---RTSMCSIQSAPPEPATL-----KGTVPDDAVEALADS 163
+A P +P E + +T + P EP P L+
Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR 845
Query: 164 LGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESK 223
+ PE KP + EK EE + +E + P + G+P L + +
Sbjct: 846 PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905
Query: 224 EQLPPMSEDFLLDALSEDFSGPQ 246
L P+ E+ L E PQ
Sbjct: 906 PPLSPLPEELPLSPSGEPSLSPQ 928
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 48.5 bits (114), Expect = 1e-05
Identities = 76/365 (20%), Positives = 152/365 (41%), Gaps = 52/365 (14%)
Query: 64 LKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 123
LKP P LP E+ +P S ++E ++ ++ + ++K + T+K E+
Sbjct: 282 LKPGQSPAIPPPLPT-EQASRPTPASPALEE--KEGEKKKAEKKVTSETKKKEKEDIKKK 338
Query: 124 APVSEAVCRTSMCSIQSAPPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKV 181
+ A+ ++ P A T +GTV A +A A KKE + KP +
Sbjct: 339 SEKETAI------DVEKKEPGKASETKQGTVKI-AAQAAAKKDEKKEDSKKTKKPAEVEQ 391
Query: 182 KEKAKEEDREKLGE------KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLL 235
+ K+E +EK E KE ++P D +++ ++ + + K+ +P E+
Sbjct: 392 PKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTT 451
Query: 236 DALSEDFSGPQNASS---------LKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSD 286
+ ++ ++ + +K ++ K+ A++ E +T +D
Sbjct: 452 KTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPET----------KKDEKMS 501
Query: 287 KDLDDALDKLSDSLGQRQ--PDPDENKPMEDKVKEKAKAEHRDKLGERDDTI---PPEYR 341
K + K G+++ P+P K + + EK + H+ + + + T+ PE +
Sbjct: 502 KAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQI-HKQDIVKPEKTVSHGKPEEK 560
Query: 342 HLLDDNGQ--DKPVKP-PTKKSEDSKK-----PADDQDPIDALSGDL-DSCPSTTETSQN 392
L +K KP PTKK+E ++ D P + ++ +S TE S+
Sbjct: 561 VLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEK 620
Query: 393 TAKDK 397
+K+K
Sbjct: 621 ESKEK 625
Score = 45.8 bits (107), Expect = 7e-05
Identities = 94/445 (21%), Positives = 171/445 (38%), Gaps = 65/445 (14%)
Query: 21 KLCDGERRGAREAVRIFQDQAK--AKEEKLEKCGEDD-ETIPSEYRLKPATDKDGKPLLP 77
K+ E+ +E VR + K +EK+EK + + +T+ E + +K
Sbjct: 161 KVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKS------ 214
Query: 78 EPEEKPKPRSESELIDELSEDFDR-SECKEKPSKPTEKTEESKAAAPAPVSE---AVCRT 133
EEK K + +++ + + E ++ PSKP EK ++ KAA + A CR
Sbjct: 215 --EEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRY 272
Query: 134 SM----------CSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKE 183
+ + PP T + + P A AL + G+K+ + K V + K+
Sbjct: 273 MIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKK---KAEKKVTSETKK 329
Query: 184 KAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFS 243
K K ED +K EKE I + K + GK K+ ++ + A +D
Sbjct: 330 KEK-EDIKKKSEKETAIDVE------KKEPGKASETKQGTVKIAAQA------AAKKDEK 376
Query: 244 GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQR 303
+ + K + + + + ++ SDK + ++ + +G
Sbjct: 377 KEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAV 436
Query: 304 QPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPV-------KPP 356
E+K + + E R + + +I + + G+++ V +P
Sbjct: 437 SIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPI---KGKEEKVPASLKEKEPE 493
Query: 357 TKKSEDSKKPADDQDP-IDALSG----------DLDSCPSTTETSQNTAKD--KCKKAAS 403
TKK E K + P L G ++ P+ +E Q +D K +K S
Sbjct: 494 TKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVS 553
Query: 404 SSKAPKNGGKAKDSAKTTEETSKPK 428
K P+ + A T E+T+KPK
Sbjct: 554 HGK-PEEKVLKQVKAVTIEKTAKPK 577
Score = 37.4 bits (85), Expect = 0.026
Identities = 73/348 (20%), Positives = 127/348 (36%), Gaps = 35/348 (10%)
Query: 87 SESELIDELSEDFDRSECKEKPSKPTE----KTEESKAAAPAPVSEAVCRTSMCSIQSAP 142
SE E D+ ED D+ E E P + E KTE+ + ++ + +
Sbjct: 116 SEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVR 175
Query: 143 PEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPP 202
+ K + +E K A + +K +EK K+E K G++E+
Sbjct: 176 EKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKE--VKGGKQEKVKQT 233
Query: 203 DYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAI 262
+++EV+ KP KE KE+ A+S+ Q A D + +
Sbjct: 234 AAKVKEVQKTPSKP-KEKEDKEKA----------AVSKHEQKDQYAFCRYMIDIFVHGDL 282
Query: 263 SEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 322
Q+PA PP T A L + G+++ ++ E K KEK
Sbjct: 283 KP--GQSPAI-----PPPLPTEQASRPTPASPALEEKEGEKK-KAEKKVTSETKKKEK-- 332
Query: 323 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 382
E K E++ I E + + G+ K T K D+ D+
Sbjct: 333 -EDIKKKSEKETAIDVEKK----EPGKASETKQGTVKIAAQAAAKKDEKKEDSKK---TK 384
Query: 383 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
P+ E + ++K +K +K+PK + +T + K++
Sbjct: 385 KPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEE 432
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 47.8 bits (112), Expect = 2e-05
Identities = 101/457 (22%), Positives = 177/457 (38%), Gaps = 100/457 (21%)
Query: 44 KEEKLEKCGEDDETIPSEYRLKPATD--KDGKPLLPEP------EEKPKPRSESELIDEL 95
K+ KL++ + E++ + P+ K+ K PE E+ PK S+ +++ +
Sbjct: 531 KQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKK 590
Query: 96 SEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTV--- 152
+ + + KPS TEK SK P+PV V ++ + T+K
Sbjct: 591 DKPI---KTETKPSV-TEKEVPSKEE-PSPVKAEVAEKQATDVKPKAAKEKTVKKETKVK 645
Query: 153 PDDAVEALADSLGKKEADPEDGKPVMDKVKEKA------------KEEDREKLGEKEETI 200
P+D E + K+ A ED P+ + K K KEE +E E ++
Sbjct: 646 PEDKKEE-KEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704
Query: 201 PPDYRLEEVKDKDGKPL-------------LPKESKEQLPPMSEDFLLDAL--------- 238
PP +EVK ++ K + LPK++K+ P+SE AL
Sbjct: 705 PPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEE 764
Query: 239 -----SEDFSGPQNASSLKF--EDAKLAAAISEVV---SQTPASTTQAG----APPRDTS 284
S P+ +K ++ K A A++ V + T A AG P ++
Sbjct: 765 SVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELE 824
Query: 285 SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLL 344
+++ L + + L+ K E+ KAE D + I P+ L+
Sbjct: 825 AERSLMSSPEDLT------------------KDFEELKAEEVDVTKD----IKPQL-ELI 861
Query: 345 DDNGQDKPVKPP-----TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAK---- 395
+D + K +P K+ E +K PA+ D + C T E + K
Sbjct: 862 EDEEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVD 921
Query: 396 --DKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
+K + + + G ++ A+ TEE +P++D
Sbjct: 922 DIEKFEDEGAGFEESSETGDYEEKAE-TEEAEEPEED 957
Score = 37.7 bits (86), Expect = 0.020
Identities = 46/183 (25%), Positives = 71/183 (38%), Gaps = 23/183 (12%)
Query: 31 REAVRIFQDQAKAKEEKLE-KCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSES 89
++A + AK K K E K +D+ E K K+ K + + EEKPK
Sbjct: 623 KQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKK-EEKPKK---E 678
Query: 90 ELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK 149
E+ E+ ++ + E KE K E K P V + V + ++ EP
Sbjct: 679 EVKKEVKKEIKKEEKKE------PKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEI 732
Query: 150 GTVPDDAVE------------ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKE 197
+P DA + AL + KKE + K KEK K + +K G+
Sbjct: 733 KKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAA 792
Query: 198 ETI 200
E +
Sbjct: 793 EAV 795
Score = 35.0 bits (79), Expect = 0.13
Identities = 90/382 (23%), Positives = 141/382 (36%), Gaps = 83/382 (21%)
Query: 39 DQAKAKEEKLEKCGEDD-ETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSE 97
+Q + E +EK G DD E E + + G + EEK +E+E +E E
Sbjct: 906 EQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETG-----DYEEK----AETEEAEEPEE 956
Query: 98 DFDRSEC-KEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDA 156
D + C PTE E +KA A A + E R S+ S D A
Sbjct: 957 DGEEHVCVSASKHSPTEDEESAKAEADAYIREK--RESVASGD--------------DRA 1000
Query: 157 VEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEE----VKDK 212
E + +++ K EA+ + E+A EED+ + +EE P E+ V DK
Sbjct: 1001 EEDMDEAIEKGEAEQSE---------EEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDK 1051
Query: 213 DGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAS 272
+ +E L ++ L G + ASS+ E
Sbjct: 1052 AAEAGGAEEQYGFLTTPTKQ-----LGAQSPGREPASSIHDE------------------ 1088
Query: 273 TTQAGAPPRDTSSDKD-LDDALDKLSDSLGQRQ--------PDP-DENKPMEDKVKEKAK 322
T G+ T+SD++ +D ++ + + G Q P P DE D + ++
Sbjct: 1089 TLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDETN 1148
Query: 323 AEHRDKLGERDDTIPPEYRHLLDDNGQDKP--VKPPTKKSEDSKKPADDQDPIDALSGDL 380
E + + I +Y L KP V P SE SK A D D
Sbjct: 1149 NEETESPSQEFVNI-TKYESSLYSQEYSKPADVTPLNGFSEGSKTDATD-------GKDY 1200
Query: 381 DSCPSTTETSQNTAKDKCKKAA 402
++ ST + +DK ++A
Sbjct: 1201 NASASTISPPSSMEEDKFSRSA 1222
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 47.4 bits (111), Expect = 3e-05
Identities = 53/205 (25%), Positives = 88/205 (42%), Gaps = 34/205 (16%)
Query: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEK-PKPRSESELIDELSE 97
D +A + L+K D E +P + T K + +P E+K KP+ + + E
Sbjct: 706 DPYRALDIDLDKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKER 765
Query: 98 DFDRSECKEKPSKPTE---KTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPD 154
D ++ + KEK ++ + T A APAP P P+T D
Sbjct: 766 DKEKKKEKEKKAEDLDFWLSTTPPPAPAPAPA----------------PVPST------D 803
Query: 155 DAVEALADSLGKKE----ADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVK 210
+ +A ++ G+++ D + P K K + ++E+R K +K + PP EE
Sbjct: 804 ECEDAKTEAQGEEDDAEGQDQDKKSPKPKKKKHRKEKEERTKGKKKSKKQPPG--SEEAA 861
Query: 211 DKDGKPLLPKESKEQLPPMSEDFLL 235
+ + P+E EQLPP S LL
Sbjct: 862 GEPVQNGAPEE--EQLPPESSYSLL 884
Score = 35.8 bits (81), Expect = 0.077
Identities = 62/271 (22%), Positives = 102/271 (37%), Gaps = 46/271 (16%)
Query: 74 PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK-----TEESKAAAPAPVSE 128
P LP ++ K E +L +D R + KEK K + TE + APA +
Sbjct: 625 PGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVD 684
Query: 129 AVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEE 188
V ++A P K P+D AL L K AD E + E +K
Sbjct: 685 IVTEEMP---ENALPSDEDDKD--PNDPYRALDIDLDKPLADSEKLPIQKHRNTETSKSP 739
Query: 189 DREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNA 248
+++ ++++ P + ++ K+K+ KE K++ +ED DF
Sbjct: 740 EKDVPMVEKKSKKPKKKEKKHKEKERD----KEKKKEKEKKAEDL-------DFW----- 783
Query: 249 SSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSDKDLD-DALDKLSDSLGQRQPDP 307
+ + P + A AP T +D +A + D+ GQ D
Sbjct: 784 ----------------LSTTPPPAPAPAPAPVPSTDECEDAKTEAQGEEDDAEGQ---DQ 824
Query: 308 DENKPMEDKVKEKAKAEHRDKLGERDDTIPP 338
D+ P K K + + E R K ++ PP
Sbjct: 825 DKKSPKPKKKKHRKEKEERTKGKKKSKKQPP 855
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 47.0 bits (110), Expect = 3e-05
Identities = 50/227 (22%), Positives = 93/227 (40%), Gaps = 29/227 (12%)
Query: 166 KKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP------ 219
K E E+ K + KE+ +++DR+ +KEE E + ++ + +LP
Sbjct: 671 KVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAII 730
Query: 220 -------KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQ---T 269
K K MS LLD ED FE + A +E++ +
Sbjct: 731 VHPNWAAKSGKFDCSIMSLSVLLDYRLED------NKEHSFEVSLFAELFNEMLQRDFGV 784
Query: 270 PASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPM-----EDKVKEKAKAE 324
+ P ++ +KD D+ D +R + DE KP +DK K++ + E
Sbjct: 785 RIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDE 844
Query: 325 HRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQD 371
+ + +DD+ + +DN QD+ +++ED + D+++
Sbjct: 845 RKKEDKRKDDSKDDDETE--EDNNQDEYDPMEAEEAEDEEDDRDEEE 889
Score = 37.0 bits (84), Expect = 0.035
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 38 QDQAKAKEEKLEKCGE-DDETI-PSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDEL 95
+D+ K+E+ +K E DDET P R K DKD K E +++ K + +S+ DE
Sbjct: 802 KDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDET 861
Query: 96 SED-----FDRSECKEKPSKPTEKTEE 117
ED +D E +E + ++ EE
Sbjct: 862 EEDNNQDEYDPMEAEEAEDEEDDRDEE 888
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 47.0 bits (110), Expect = 3e-05
Identities = 86/421 (20%), Positives = 162/421 (38%), Gaps = 65/421 (15%)
Query: 44 KEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSE 103
K+++ +KC ++ + +++ DK+ K L + +EK + + ++ SE D +
Sbjct: 1048 KDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKK 1107
Query: 104 CKEK----PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEA 159
KEK T+++E+ + + C S + A P T ++ EA
Sbjct: 1108 GKEKSWYIADIFTDESEDDRDS---------CMGSGFKMGEASDLPRTDGLQEKEEGREA 1158
Query: 160 LADSLGKKEAD-----------PED----------GKPVMDKVKEKAKEEDREKLGEKEE 198
A +K +D P D G+ +KV EK KE+ ++ EK +
Sbjct: 1159 YASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYK 1218
Query: 199 TIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKL 258
++ +DK K LP++++++ +ED A S+ S + + ++
Sbjct: 1219 DRKDRASVDSTQDKKNKQKLPEKAEKK--HAAED---KAKSKHKEKSDKEHSKERKSSRS 1273
Query: 259 AAAISEVVSQTPASTTQAGAPPRDTSSDKDLDDALDKLSDSLGQR-----------QPDP 307
A A ++ + +A R+ S+DK + + D +D GQ P
Sbjct: 1274 ADAEKSLLEKL---EEEALHEYREDSNDKISEVSSDSFTDR-GQEPGLTAFLEVSFTEPP 1329
Query: 308 DENKPME-----DKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 362
++KP E +K+KEK + H ++ R +K K K
Sbjct: 1330 GDDKPRESACLPEKLKEKERHRHSSSSSKKSHD-----RERAKKEKAEKKEKGEDYKEGG 1384
Query: 363 SKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTE 422
S+K + + D L D + DK + S+ K KN + + S K +
Sbjct: 1385 SRKDSGQYEK-DFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEK 1443
Query: 423 E 423
E
Sbjct: 1444 E 1444
Score = 33.5 bits (75), Expect = 0.38
Identities = 54/228 (23%), Positives = 93/228 (40%), Gaps = 29/228 (12%)
Query: 167 KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQL 226
KE P++ K + K + K K +DR EK+ + D ++ + K+K + KE KE+L
Sbjct: 749 KEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKED-KISKEKEK-----IFKEDKEKL 802
Query: 227 PPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSSD 286
+ + D+ +++ L+ ED K + + + + + + S D
Sbjct: 803 -KKEKVYREDSAFDEYCNKN--QFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWD 859
Query: 287 KDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD-KLGERDDTIPPEY----R 341
+ D D SDS+ K + + VKE +K RD + E+ D P + R
Sbjct: 860 SPVTDYRDMKSDSVA---------KLILETVKEDSKERRRDSRAREKRDYREPFFRKKDR 910
Query: 342 HLLDDNGQ------DKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSC 383
LD N + +K P SE KK + + L+SC
Sbjct: 911 DYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESC 958
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.124 0.344
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,337,262
Number of Sequences: 37866
Number of extensions: 1167448
Number of successful extensions: 7945
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 675
Number of HSP's that attempted gapping in prelim test: 5403
Number of HSP's gapped (non-prelim): 2304
length of query: 430
length of database: 18,247,518
effective HSP length: 105
effective length of query: 325
effective length of database: 14,271,588
effective search space: 4638266100
effective search space used: 4638266100
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.