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Search of human proteins with 26190614
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26190614 rhotekin 2 [Homo sapiens]
(609 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26190614 rhotekin 2 [Homo sapiens] 1234 0.0
gi|62739179 rhotekin isoform a [Homo sapiens] 391 e-108
gi|19526471 rhotekin isoform b [Homo sapiens] 391 e-108
gi|62739181 rhotekin isoform c [Homo sapiens] 376 e-104
gi|31657094 anillin, actin binding protein [Homo sapiens] 67 4e-11
gi|197382472 actin filament associated protein 1 isoform a [Homo... 37 0.040
gi|40807504 actin filament associated protein 1 [Homo sapiens] 37 0.040
gi|238859653 pleckstrin homology domain containing family A memb... 33 0.58
gi|238859651 pleckstrin homology domain containing family A memb... 33 0.58
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 33 0.58
gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens] 32 1.7
gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens] 32 1.7
gi|24586663 adaptor protein, phosphotyrosine interaction, PH dom... 32 2.2
gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens] 31 2.9
gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens] 31 2.9
gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens] 31 2.9
gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens] 31 2.9
gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens] 31 2.9
gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens] 31 2.9
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 31 2.9
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 31 2.9
gi|21389395 hypothetical protein LOC123970 [Homo sapiens] 31 2.9
gi|20373171 vang-like 1 [Homo sapiens] 31 3.8
gi|188497618 connector enhancer of kinase suppressor of Ras 1 [H... 31 3.8
gi|239047795 pleckstrin homology domain containing, family A mem... 30 4.9
gi|32483410 vitamin D-binding protein precursor [Homo sapiens] 30 6.5
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 30 6.5
gi|212549782 caspase 8 associated protein 2 [Homo sapiens] 30 8.4
gi|6912288 caspase 8 associated protein 2 [Homo sapiens] 30 8.4
gi|212549532 caspase 8 associated protein 2 [Homo sapiens] 30 8.4
>gi|26190614 rhotekin 2 [Homo sapiens]
Length = 609
Score = 1234 bits (3194), Expect = 0.0
Identities = 609/609 (100%), Positives = 609/609 (100%)
Query: 1 MEGPSLRGPALRLAGLPTQQDCNIQEKIDLEIRMREGIWKLLSLSTQKDQVLHAVKNLMV 60
MEGPSLRGPALRLAGLPTQQDCNIQEKIDLEIRMREGIWKLLSLSTQKDQVLHAVKNLMV
Sbjct: 1 MEGPSLRGPALRLAGLPTQQDCNIQEKIDLEIRMREGIWKLLSLSTQKDQVLHAVKNLMV 60
Query: 61 CNARLMAYTSELQKLEEQIANQTGRCDVKFESKERTACKGKIAISDIRIPLMWKDSDHFS 120
CNARLMAYTSELQKLEEQIANQTGRCDVKFESKERTACKGKIAISDIRIPLMWKDSDHFS
Sbjct: 61 CNARLMAYTSELQKLEEQIANQTGRCDVKFESKERTACKGKIAISDIRIPLMWKDSDHFS 120
Query: 121 NKERSRRYAIFCLFKMGANVFDTDVVNVDKTITDICFENVTIFNEAGPDFQIKVEVYSCC 180
NKERSRRYAIFCLFKMGANVFDTDVVNVDKTITDICFENVTIFNEAGPDFQIKVEVYSCC
Sbjct: 121 NKERSRRYAIFCLFKMGANVFDTDVVNVDKTITDICFENVTIFNEAGPDFQIKVEVYSCC 180
Query: 181 TEESSITNTPKKLAKKLKTSISKATGKKISSVLQEEDDEMCLLLSSAVFGVKYNLLAHTT 240
TEESSITNTPKKLAKKLKTSISKATGKKISSVLQEEDDEMCLLLSSAVFGVKYNLLAHTT
Sbjct: 181 TEESSITNTPKKLAKKLKTSISKATGKKISSVLQEEDDEMCLLLSSAVFGVKYNLLAHTT 240
Query: 241 LTLESAEDSFKTHNLSINGNEESSFWLPLYGNMCCRLVAQPACMAEDAFAGFLNQQQMVE 300
LTLESAEDSFKTHNLSINGNEESSFWLPLYGNMCCRLVAQPACMAEDAFAGFLNQQQMVE
Sbjct: 241 LTLESAEDSFKTHNLSINGNEESSFWLPLYGNMCCRLVAQPACMAEDAFAGFLNQQQMVE 300
Query: 301 GLISWRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKDAKKRIHNFSV 360
GLISWRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKDAKKRIHNFSV
Sbjct: 301 GLISWRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKDAKKRIHNFSV 360
Query: 361 INPVPGQAITQIFAVDNREDLQKWMEAFWQHFFDLSQWKHCCEELMKIEIMSPRKPPLFL 420
INPVPGQAITQIFAVDNREDLQKWMEAFWQHFFDLSQWKHCCEELMKIEIMSPRKPPLFL
Sbjct: 361 INPVPGQAITQIFAVDNREDLQKWMEAFWQHFFDLSQWKHCCEELMKIEIMSPRKPPLFL 420
Query: 421 TKEATSVYHDMSIDSPMKLESLTDIIQKKIEETNGQFLIGQHEESLPPPWATLFDGNHQM 480
TKEATSVYHDMSIDSPMKLESLTDIIQKKIEETNGQFLIGQHEESLPPPWATLFDGNHQM
Sbjct: 421 TKEATSVYHDMSIDSPMKLESLTDIIQKKIEETNGQFLIGQHEESLPPPWATLFDGNHQM 480
Query: 481 VIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQLVKDNWGKTSVSQTSS 540
VIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQLVKDNWGKTSVSQTSS
Sbjct: 481 VIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQLVKDNWGKTSVSQTSS 540
Query: 541 LDTKLSTLMHHLQKPMAAPRKLLPARRNRLSDGEHTDTKTNFEAKPVPAPRQKSIKDILD 600
LDTKLSTLMHHLQKPMAAPRKLLPARRNRLSDGEHTDTKTNFEAKPVPAPRQKSIKDILD
Sbjct: 541 LDTKLSTLMHHLQKPMAAPRKLLPARRNRLSDGEHTDTKTNFEAKPVPAPRQKSIKDILD 600
Query: 601 PRSWLQAQV 609
PRSWLQAQV
Sbjct: 601 PRSWLQAQV 609
>gi|62739179 rhotekin isoform a [Homo sapiens]
Length = 563
Score = 391 bits (1004), Expect = e-108
Identities = 197/462 (42%), Positives = 302/462 (65%), Gaps = 19/462 (4%)
Query: 20 QDCNIQEKIDLEIRMREGIWKLLSLSTQKDQVLHAVKNLMVCNARLMAYTSELQKLEE-Q 78
+D +Q K+D EIRMREG KLL+ +Q++Q L A K+L+VCN+R+++Y ELQ+ +E Q
Sbjct: 37 EDTELQRKLDHEIRMREGACKLLAACSQREQALEATKSLLVCNSRILSYMGELQRRKEAQ 96
Query: 79 IANQTGRCDVKF-ESKERTACKGKIAISDIRIPLMWKDSDHFSNKERSRRYAIFCLFKMG 137
+ +T R ER+ C+G++ ISD+RIPLMWKD+++F NK R+A+F L ++G
Sbjct: 97 VLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKNKGDLHRWAVFLLLQLG 156
Query: 138 ANVFDTDVVNVDKTITDICFENVTIFNEAGPDFQIKVEVYSCCT-EESSITNTPKKLAKK 196
++ DT+++ VD+T+TDI F++ +F EAGPDF++++E+Y C EE ++T PK+LA K
Sbjct: 157 EHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACVEEEGALTGGPKRLATK 216
Query: 197 LKTSISKATGKKISSVLQE---EDDEMCLLLSSAVFGVKYNLLAHTTLTLESAEDSFKTH 253
L +S+ +++G+++ + L LL + V G +Y+LLAHTTLTL + +D F+TH
Sbjct: 217 LSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLAHTTLTLAAVQDGFRTH 276
Query: 254 NLSINGNEESSFWLPLYGNMCCRLVAQPACMAEDAFAGFLNQQQMVEGLISWRRLYCVLR 313
+L++ +EE+ WLPLYG++CCRL AQP CM + +G L QQ E + +W +++ VL+
Sbjct: 277 DLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQAGE-MQNWAQVHGVLK 335
Query: 314 GGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKD-AKKRIHNFSVINPVPGQAITQI 372
G L+C+ PE+ + EP L + +NKETR+RA + D A R S+ N +T
Sbjct: 336 GTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFTLSISNQYGDDEVTHT 395
Query: 373 FAVDNREDLQKWMEAFWQHFFDLSQWKHCCEELMKIEIMSPRKPPLFLTKEATSVYHDMS 432
++RE LQ WMEA WQ FFD+SQWK CC+E+MKIE +PRKPP L K+ S+YH+M+
Sbjct: 396 LQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPPQALAKQG-SLYHEMA 454
Query: 433 IDSPMKLESLTDIIQKKIEETNGQFLIGQHEESLPPPWATLF 474
I+ + ++TDI+ ++ G L PPPW +F
Sbjct: 455 IEPLDDIAAVTDILTQR----EGARL------ETPPPWLAMF 486
>gi|19526471 rhotekin isoform b [Homo sapiens]
Length = 550
Score = 391 bits (1004), Expect = e-108
Identities = 197/462 (42%), Positives = 302/462 (65%), Gaps = 19/462 (4%)
Query: 20 QDCNIQEKIDLEIRMREGIWKLLSLSTQKDQVLHAVKNLMVCNARLMAYTSELQKLEE-Q 78
+D +Q K+D EIRMREG KLL+ +Q++Q L A K+L+VCN+R+++Y ELQ+ +E Q
Sbjct: 24 EDTELQRKLDHEIRMREGACKLLAACSQREQALEATKSLLVCNSRILSYMGELQRRKEAQ 83
Query: 79 IANQTGRCDVKF-ESKERTACKGKIAISDIRIPLMWKDSDHFSNKERSRRYAIFCLFKMG 137
+ +T R ER+ C+G++ ISD+RIPLMWKD+++F NK R+A+F L ++G
Sbjct: 84 VLGKTSRRPSDSGPPAERSPCRGRVCISDLRIPLMWKDTEYFKNKGDLHRWAVFLLLQLG 143
Query: 138 ANVFDTDVVNVDKTITDICFENVTIFNEAGPDFQIKVEVYSCCT-EESSITNTPKKLAKK 196
++ DT+++ VD+T+TDI F++ +F EAGPDF++++E+Y C EE ++T PK+LA K
Sbjct: 144 EHIQDTEMILVDRTLTDISFQSNVLFAEAGPDFELRLELYGACVEEEGALTGGPKRLATK 203
Query: 197 LKTSISKATGKKISSVLQE---EDDEMCLLLSSAVFGVKYNLLAHTTLTLESAEDSFKTH 253
L +S+ +++G+++ + L LL + V G +Y+LLAHTTLTL + +D F+TH
Sbjct: 204 LSSSLGRSSGRRVRASLDSAGGSGSSPILLPTPVVGGPRYHLLAHTTLTLAAVQDGFRTH 263
Query: 254 NLSINGNEESSFWLPLYGNMCCRLVAQPACMAEDAFAGFLNQQQMVEGLISWRRLYCVLR 313
+L++ +EE+ WLPLYG++CCRL AQP CM + +G L QQ E + +W +++ VL+
Sbjct: 264 DLTLASHEENPAWLPLYGSVCCRLAAQPLCMTQPTASGTLRVQQAGE-MQNWAQVHGVLK 322
Query: 314 GGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKD-AKKRIHNFSVINPVPGQAITQI 372
G L+C+ PE+ + EP L + +NKETR+RA + D A R S+ N +T
Sbjct: 323 GTNLFCYRQPEDADTGEEPLLTIAVNKETRVRAGELDQALGRPFTLSISNQYGDDEVTHT 382
Query: 373 FAVDNREDLQKWMEAFWQHFFDLSQWKHCCEELMKIEIMSPRKPPLFLTKEATSVYHDMS 432
++RE LQ WMEA WQ FFD+SQWK CC+E+MKIE +PRKPP L K+ S+YH+M+
Sbjct: 383 LQTESREALQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPPQALAKQG-SLYHEMA 441
Query: 433 IDSPMKLESLTDIIQKKIEETNGQFLIGQHEESLPPPWATLF 474
I+ + ++TDI+ ++ G L PPPW +F
Sbjct: 442 IEPLDDIAAVTDILTQR----EGARL------ETPPPWLAMF 473
>gi|62739181 rhotekin isoform c [Homo sapiens]
Length = 513
Score = 376 bits (966), Expect = e-104
Identities = 190/448 (42%), Positives = 292/448 (65%), Gaps = 19/448 (4%)
Query: 34 MREGIWKLLSLSTQKDQVLHAVKNLMVCNARLMAYTSELQKLEE-QIANQTGRCDVKF-E 91
MREG KLL+ +Q++Q L A K+L+VCN+R+++Y ELQ+ +E Q+ +T R
Sbjct: 1 MREGACKLLAACSQREQALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGP 60
Query: 92 SKERTACKGKIAISDIRIPLMWKDSDHFSNKERSRRYAIFCLFKMGANVFDTDVVNVDKT 151
ER+ C+G++ ISD+RIPLMWKD+++F NK R+A+F L ++G ++ DT+++ VD+T
Sbjct: 61 PAERSPCRGRVCISDLRIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRT 120
Query: 152 ITDICFENVTIFNEAGPDFQIKVEVYSCCT-EESSITNTPKKLAKKLKTSISKATGKKIS 210
+TDI F++ +F EAGPDF++++E+Y C EE ++T PK+LA KL +S+ +++G+++
Sbjct: 121 LTDISFQSNVLFAEAGPDFELRLELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVR 180
Query: 211 SVLQE---EDDEMCLLLSSAVFGVKYNLLAHTTLTLESAEDSFKTHNLSINGNEESSFWL 267
+ L LL + V G +Y+LLAHTTLTL + +D F+TH+L++ +EE+ WL
Sbjct: 181 ASLDSAGGSGSSPILLPTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWL 240
Query: 268 PLYGNMCCRLVAQPACMAEDAFAGFLNQQQMVEGLISWRRLYCVLRGGKLYCFYSPEEIE 327
PLYG++CCRL AQP CM + +G L QQ E + +W +++ VL+G L+C+ PE+ +
Sbjct: 241 PLYGSVCCRLAAQPLCMTQPTASGTLRVQQAGE-MQNWAQVHGVLKGTNLFCYRQPEDAD 299
Query: 328 AKVEPALVVPINKETRIRAMDKD-AKKRIHNFSVINPVPGQAITQIFAVDNREDLQKWME 386
EP L + +NKETR+RA + D A R S+ N +T ++RE LQ WME
Sbjct: 300 TGEEPLLTIAVNKETRVRAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREALQSWME 359
Query: 387 AFWQHFFDLSQWKHCCEELMKIEIMSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDII 446
A WQ FFD+SQWK CC+E+MKIE +PRKPP L K+ S+YH+M+I+ + ++TDI+
Sbjct: 360 ALWQLFFDMSQWKQCCDEIMKIETPAPRKPPQALAKQG-SLYHEMAIEPLDDIAAVTDIL 418
Query: 447 QKKIEETNGQFLIGQHEESLPPPWATLF 474
++ G L PPPW +F
Sbjct: 419 TQR----EGARL------ETPPPWLAMF 436
>gi|31657094 anillin, actin binding protein [Homo sapiens]
Length = 1124
Score = 67.4 bits (163), Expect = 4e-11
Identities = 84/372 (22%), Positives = 152/372 (40%), Gaps = 43/372 (11%)
Query: 54 AVKNLMVCNARLMAYTSELQKLEEQIANQTGRCDVKFESKERTACKGKIAISDIRIPLMW 113
A + L++ + EL KL+ + + + + E KG + +S+IR+PL
Sbjct: 759 AERLLLIATGKRTLLIDELNKLKNEGPQRKNKASPQ---SEFMPSKGSVTLSEIRLPLKA 815
Query: 114 KDSDHFSNKERSRRYAIFCLFKMGA-NVFDTDVVNVDKTITDICFENVTIFN--EAGPDF 170
K + Y + K GA N+ T + + ++ T F + DF
Sbjct: 816 DFVCSTVQKPDAANYYYLIILKAGAENMVATPLASTSNSLNGDALTFTTTFTLQDVSNDF 875
Query: 171 QIKVEVYSCCTEESSITNTPKKLAKKLKTSISKATGKK--ISSVLQEEDDEMCLLLS--- 225
+I +EVYS ++ P L KK KTS SKA K ++S+ + + ++ S
Sbjct: 876 EINIEVYSLVQKKD-----PSGLDKKKKTSKSKAITPKRLLTSITTKSNIHSSVMASPGG 930
Query: 226 -SAVFGVKYNLLAHTTLTLESAEDSFKTHNLSINGNEESSFWLPLYGNMCCRLVAQPACM 284
SAV + L+ TL+L S ++ ++ F L G++ ++ Q
Sbjct: 931 LSAVRTSNFALVGSYTLSLSSVGNTKFVL-------DKVPFLSSLEGHIYLKIKCQVNSS 983
Query: 285 AEDAFAGFLNQQQMVEGLISWRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETR- 343
E+ GFL + V G +W R +CVL G + + P++ + K + N +R
Sbjct: 984 VEER--GFLTIFEDVSGFGAWHRRWCVLSGNCISYWTYPDDEKRKNPIGRINLANCTSRQ 1041
Query: 344 IRAMDKDAKKRIHNFSVINPVPGQ------AITQI----------FAVDNREDLQKWMEA 387
I +++ R + F +I P + ++Q + D +E+ WM+
Sbjct: 1042 IEPANREFCARRNTFELITVRPQREDDRETLVSQCRDTLCVTKNWLSADTKEERDLWMQK 1101
Query: 388 FWQHFFDLSQWK 399
Q D+ W+
Sbjct: 1102 LNQVLVDIRLWQ 1113
>gi|197382472 actin filament associated protein 1 isoform a [Homo
sapiens]
Length = 814
Score = 37.4 bits (85), Expect = 0.040
Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 8/82 (9%)
Query: 305 WRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKDAKKRIHNFSVINPV 364
W +L CV++ KL C+ S ++ + ++E L + I + KD+KK+ H +
Sbjct: 169 WTKLLCVIKDTKLLCYKSSKDQQPQMELPL-----QGCNITYIPKDSKKKKHELKITQQG 223
Query: 365 PGQAITQIFAVDNREDLQKWME 386
+ AV ++E ++W++
Sbjct: 224 TDPL---VLAVQSKEQAEQWLK 242
>gi|40807504 actin filament associated protein 1 [Homo sapiens]
Length = 730
Score = 37.4 bits (85), Expect = 0.040
Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 8/82 (9%)
Query: 305 WRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKDAKKRIHNFSVINPV 364
W +L CV++ KL C+ S ++ + ++E L + I + KD+KK+ H +
Sbjct: 169 WTKLLCVIKDTKLLCYKSSKDQQPQMELPL-----QGCNITYIPKDSKKKKHELKITQQG 223
Query: 365 PGQAITQIFAVDNREDLQKWME 386
+ AV ++E ++W++
Sbjct: 224 TDPL---VLAVQSKEQAEQWLK 242
>gi|238859653 pleckstrin homology domain containing family A member
4 isoform 2 [Homo sapiens]
Length = 583
Score = 33.5 bits (75), Expect = 0.58
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 8/97 (8%)
Query: 291 GFLNQQQMVEGLISWRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKD 350
G+L++Q GL W+R + VL G L FY + E V ++++P IR D
Sbjct: 59 GWLHKQDS-SGLRLWKRRWFVLSGHCL--FYYKDSREESVLGSVLLP---SYNIRP-DGP 111
Query: 351 AKKRIHNFSVINPVPGQAITQIFAVDNREDLQKWMEA 387
R F+ PG T + A D EDL+ W+ A
Sbjct: 112 GAPRGRRFTFTAEHPGMR-TYVLAADTLEDLRGWLRA 147
>gi|238859651 pleckstrin homology domain containing family A member
4 isoform 1 [Homo sapiens]
Length = 779
Score = 33.5 bits (75), Expect = 0.58
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 8/97 (8%)
Query: 291 GFLNQQQMVEGLISWRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKD 350
G+L++Q GL W+R + VL G L FY + E V ++++P IR D
Sbjct: 59 GWLHKQDS-SGLRLWKRRWFVLSGHCL--FYYKDSREESVLGSVLLP---SYNIRP-DGP 111
Query: 351 AKKRIHNFSVINPVPGQAITQIFAVDNREDLQKWMEA 387
R F+ PG T + A D EDL+ W+ A
Sbjct: 112 GAPRGRRFTFTAEHPGMR-TYVLAADTLEDLRGWLRA 147
>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
Length = 2390
Score = 33.5 bits (75), Expect = 0.58
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 281 PACMAEDAFAGFLNQQQMVEGL------ISWRRLYCVLRGGKLYCFYSPEEIEAKVEPAL 334
P A++ G L ++Q +E SW+ +YCVLR G L + + A V
Sbjct: 2213 PEPSAQEQMEGMLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHG 2272
Query: 335 VVPINKETRIRAMDKDAKKRIHNFSV 360
VP++ ++ D +KR H F +
Sbjct: 2273 EVPVSLARAQGSVAFDYRKRKHVFKL 2298
>gi|71979665 growth factor receptor-bound protein 7 [Homo sapiens]
Length = 532
Score = 32.0 bits (71), Expect = 1.7
Identities = 45/204 (22%), Positives = 75/204 (36%), Gaps = 25/204 (12%)
Query: 286 EDAFAGFLNQQQMVE----------GLISWRRLYCVLRGGKLYCFYS-------PEEIE- 327
ED FLN E G W+R +C LR LY YS P ++
Sbjct: 217 EDLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLY--YSTKGTSKDPRHLQY 274
Query: 328 -AKVEPALVVPINKETRIRAMDKDAKKRIHNFSVINPVPGQAITQIFAVDNREDLQKWME 386
A V + V + + ++ M D + + N G +IF ++ + W+
Sbjct: 275 VADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRN---GHKGLRIFCSEDEQSRTCWLA 331
Query: 387 AFWQHFFDLSQWKHCCEELMK-IEIMSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDI 445
AF + + +K+ + + + PPL + T V D S + +E+ +
Sbjct: 332 AFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREA 391
Query: 446 IQKKIEETNGQFLIGQHEESLPPP 469
+ +EE H SLP P
Sbjct: 392 LSVALEEAQAWRKKTNHRLSLPMP 415
>gi|71979667 growth factor receptor-bound protein 7 [Homo sapiens]
Length = 532
Score = 32.0 bits (71), Expect = 1.7
Identities = 45/204 (22%), Positives = 75/204 (36%), Gaps = 25/204 (12%)
Query: 286 EDAFAGFLNQQQMVE----------GLISWRRLYCVLRGGKLYCFYS-------PEEIE- 327
ED FLN E G W+R +C LR LY YS P ++
Sbjct: 217 EDLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLY--YSTKGTSKDPRHLQY 274
Query: 328 -AKVEPALVVPINKETRIRAMDKDAKKRIHNFSVINPVPGQAITQIFAVDNREDLQKWME 386
A V + V + + ++ M D + + N G +IF ++ + W+
Sbjct: 275 VADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRN---GHKGLRIFCSEDEQSRTCWLA 331
Query: 387 AFWQHFFDLSQWKHCCEELMK-IEIMSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDI 445
AF + + +K+ + + + PPL + T V D S + +E+ +
Sbjct: 332 AFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREA 391
Query: 446 IQKKIEETNGQFLIGQHEESLPPP 469
+ +EE H SLP P
Sbjct: 392 LSVALEEAQAWRKKTNHRLSLPMP 415
>gi|24586663 adaptor protein, phosphotyrosine interaction, PH domain
and leucine zipper containing 2 [Homo sapiens]
Length = 664
Score = 31.6 bits (70), Expect = 2.2
Identities = 62/310 (20%), Positives = 120/310 (38%), Gaps = 39/310 (12%)
Query: 290 AGFLNQQQMVEGLIS--WRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAM 347
AG+LN + GL++ W RLY +GG L C + V L+ ++ M
Sbjct: 281 AGYLNLRNKT-GLVTTTWERLYFFTQGGNLMC-----QPRGAVAGGLIQDLD---NCSVM 331
Query: 348 DKDAKKRIHNFSVINPVPGQAITQIFAVDNREDLQKWMEAFWQHFFDLSQWKHCCEELMK 407
D + R + F + P I I ++R++ ++W+ A ++S+ + +
Sbjct: 332 AVDCEDRRYCFQITTPNGKSGI--ILQAESRKENEEWICA----INNISRQIYLTD---- 381
Query: 408 IEIMSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDIIQKKIE-ETNGQFLIGQHEESL 466
+P + L + A ++ + S K E E ++ + SL
Sbjct: 382 ----NPEAVAIKLNQTALQAVTPITSFGKKQESSCPSQNLKNSEMENENDKIVPKATASL 437
Query: 467 PPPWATLFDGNHQMVIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQL- 525
P + G IQ ++ PA+E L +G +R P ++ F S Q+
Sbjct: 438 PEAEELIAPGT---PIQFDIVLPATEFLDQNRGSRRTNPFGETEDESFPEAEDSLLQQMF 494
Query: 526 VKDNWGKTSVSQTSSLDTKLSTL--------MHHLQKPMAAPRKLLPARRNRLSDGEHTD 577
+ G +V S+ + + +H++ + M ++ ++ RL D +
Sbjct: 495 IVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIFR-MTESHLMVTSQSLRLIDPQTQV 553
Query: 578 TKTNFEAKPV 587
++ NFE V
Sbjct: 554 SRANFELTSV 563
>gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens]
Length = 590
Score = 31.2 bits (69), Expect = 2.9
Identities = 37/162 (22%), Positives = 61/162 (37%), Gaps = 12/162 (7%)
Query: 411 MSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDIIQKKIEETNGQFLIGQHE-----ES 465
MSP + ++ + +V M + P+ L + + +KK + QF H S
Sbjct: 402 MSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNS 461
Query: 466 LPPPWATLFDGNHQMVIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQL 525
LP + + Q+ PA EP+ +R P+ + L+ SNT
Sbjct: 462 LPASPLRIVEDEEYETTQE--YEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNT--- 516
Query: 526 VKDNWGKTSVSQTSSLDTKLSTLMHHLQKPMAAPRKLLPARR 567
+ S S+T T +Q P+AA + PA R
Sbjct: 517 --SSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFR 556
>gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens]
Length = 624
Score = 31.2 bits (69), Expect = 2.9
Identities = 37/162 (22%), Positives = 61/162 (37%), Gaps = 12/162 (7%)
Query: 411 MSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDIIQKKIEETNGQFLIGQHE-----ES 465
MSP + ++ + +V M + P+ L + + +KK + QF H S
Sbjct: 436 MSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNS 495
Query: 466 LPPPWATLFDGNHQMVIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQL 525
LP + + Q+ PA EP+ +R P+ + L+ SNT
Sbjct: 496 LPASPLRIVEDEEYETTQE--YEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNT--- 550
Query: 526 VKDNWGKTSVSQTSSLDTKLSTLMHHLQKPMAAPRKLLPARR 567
+ S S+T T +Q P+AA + PA R
Sbjct: 551 --SSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFR 590
>gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens]
Length = 607
Score = 31.2 bits (69), Expect = 2.9
Identities = 37/162 (22%), Positives = 61/162 (37%), Gaps = 12/162 (7%)
Query: 411 MSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDIIQKKIEETNGQFLIGQHE-----ES 465
MSP + ++ + +V M + P+ L + + +KK + QF H S
Sbjct: 419 MSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNS 478
Query: 466 LPPPWATLFDGNHQMVIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQL 525
LP + + Q+ PA EP+ +R P+ + L+ SNT
Sbjct: 479 LPASPLRIVEDEEYETTQE--YEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNT--- 533
Query: 526 VKDNWGKTSVSQTSSLDTKLSTLMHHLQKPMAAPRKLLPARR 567
+ S S+T T +Q P+AA + PA R
Sbjct: 534 --SSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFR 573
>gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens]
Length = 637
Score = 31.2 bits (69), Expect = 2.9
Identities = 37/162 (22%), Positives = 61/162 (37%), Gaps = 12/162 (7%)
Query: 411 MSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDIIQKKIEETNGQFLIGQHE-----ES 465
MSP + ++ + +V M + P+ L + + +KK + QF H S
Sbjct: 449 MSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNS 508
Query: 466 LPPPWATLFDGNHQMVIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQL 525
LP + + Q+ PA EP+ +R P+ + L+ SNT
Sbjct: 509 LPASPLRIVEDEEYETTQE--YEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNT--- 563
Query: 526 VKDNWGKTSVSQTSSLDTKLSTLMHHLQKPMAAPRKLLPARR 567
+ S S+T T +Q P+AA + PA R
Sbjct: 564 --SSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFR 603
>gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens]
Length = 645
Score = 31.2 bits (69), Expect = 2.9
Identities = 37/162 (22%), Positives = 61/162 (37%), Gaps = 12/162 (7%)
Query: 411 MSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDIIQKKIEETNGQFLIGQHE-----ES 465
MSP + ++ + +V M + P+ L + + +KK + QF H S
Sbjct: 457 MSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNS 516
Query: 466 LPPPWATLFDGNHQMVIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQL 525
LP + + Q+ PA EP+ +R P+ + L+ SNT
Sbjct: 517 LPASPLRIVEDEEYETTQE--YEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNT--- 571
Query: 526 VKDNWGKTSVSQTSSLDTKLSTLMHHLQKPMAAPRKLLPARR 567
+ S S+T T +Q P+AA + PA R
Sbjct: 572 --SSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFR 611
>gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens]
Length = 640
Score = 31.2 bits (69), Expect = 2.9
Identities = 37/162 (22%), Positives = 61/162 (37%), Gaps = 12/162 (7%)
Query: 411 MSPRKPPLFLTKEATSVYHDMSIDSPMKLESLTDIIQKKIEETNGQFLIGQHE-----ES 465
MSP + ++ + +V M + P+ L + + +KK + QF H S
Sbjct: 452 MSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNS 511
Query: 466 LPPPWATLFDGNHQMVIQKKVLYPASEPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQL 525
LP + + Q+ PA EP+ +R P+ + L+ SNT
Sbjct: 512 LPASPLRIVEDEEYETTQE--YEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNT--- 566
Query: 526 VKDNWGKTSVSQTSSLDTKLSTLMHHLQKPMAAPRKLLPARR 567
+ S S+T T +Q P+AA + PA R
Sbjct: 567 --SSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFR 606
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 31.2 bits (69), Expect = 2.9
Identities = 23/103 (22%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 290 AGFLNQQQMVEGLISWRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDK 349
AG+L +Q+ + + +W++ + VLRG +L FY ++ E K + + + + T + +
Sbjct: 41 AGWLKKQRSI--MKNWQQRWFVLRGDQL--FYYKDKDEIKPQGFISLQGTQVTELPPGPE 96
Query: 350 DAKKRIHNFS-----VINPVPGQAITQIFAVDNREDLQKWMEA 387
D K + S VP + ++ D++ W++A
Sbjct: 97 DPGKHLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQA 139
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 31.2 bits (69), Expect = 2.9
Identities = 18/84 (21%), Positives = 42/84 (50%), Gaps = 9/84 (10%)
Query: 305 WRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRIRAMDKDAKKRIHNFSVINPV 364
W+ + V++ LY + + E++ A P+ T I+ D++++ ++ F +++
Sbjct: 1350 WKHFWFVIKNKVLYTYAASEDVAALESQ----PLLGFTVIQVKDENSESKV--FQLLHK- 1402
Query: 365 PGQAITQIFAVDNREDLQKWMEAF 388
+ +F ++ QKW+EAF
Sbjct: 1403 --NMLFYVFKAEDAHSAQKWIEAF 1424
>gi|21389395 hypothetical protein LOC123970 [Homo sapiens]
Length = 265
Score = 31.2 bits (69), Expect = 2.9
Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 8/114 (7%)
Query: 492 EPLHDEKGKKRQAPLPPSDKLPFSLKSQSNTDQLVKDNWGKTSVSQTSSLDTKLS--TLM 549
E L +GKK+QAP K+ LK ++ K G + + DT+ S L
Sbjct: 36 EWLERRQGKKKQAPEKQKPKVVTVLKRNKKKEE--KKGKGLMTARGGNRRDTETSQQALG 93
Query: 550 HHLQKPMAAPRKLLPARRNRLSDGEHTDTKTNFEAKPVPAPRQKSIKDILDPRS 603
+K A+ R L + G+H K P IKD +DP S
Sbjct: 94 KRFRKDAASYRSLYGVEQK----GKHLSMVPGSYIKDGPKKSDTDIKDAVDPES 143
>gi|20373171 vang-like 1 [Homo sapiens]
Length = 524
Score = 30.8 bits (68), Expect = 3.8
Identities = 12/51 (23%), Positives = 26/51 (50%)
Query: 496 DEKGKKRQAPLPPSDKLPFSLKSQSNTDQLVKDNWGKTSVSQTSSLDTKLS 546
D +G ++ + P P + T+++ DNWG+T+ + T + + +S
Sbjct: 38 DGRGSEKSVTIQPPTGEPLLGNDSTRTEEVQDDNWGETTTAITGTSEHSIS 88
>gi|188497618 connector enhancer of kinase suppressor of Ras 1 [Homo
sapiens]
Length = 713
Score = 30.8 bits (68), Expect = 3.8
Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 22/115 (19%)
Query: 275 CRLVAQPAC----MAEDAFAGFLNQQQMVEGLISWRRLYCVLRGGKLYCFYSPEEIEAKV 330
CR + +P C + A GF+ + WRR + VL+G LY + P++ +A+
Sbjct: 391 CRELGRPDCDGWLLLRKAPGGFMGPR--------WRRRWFVLKGHTLYWYRQPQDEKAE- 441
Query: 331 EPALVVPINKETRIRAMDKDAKKRIHNFSVINPVPGQAITQIFAVDNREDLQKWM 385
IN D KK+ + F + + V IFA D DL W+
Sbjct: 442 -----GLINVSNYSLESGHDQKKK-YVFQLTHDVYKPF---IFAADTLTDLSMWV 487
>gi|239047795 pleckstrin homology domain containing, family A member
7 [Homo sapiens]
Length = 1121
Score = 30.4 bits (67), Expect = 4.9
Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 19/115 (16%)
Query: 291 GFLNQQQMVEGLISWRRLYCVLRGGKLYC-FYSPEEIEAKVEPALVVP------------ 337
G+L++Q G+ W+R + VL YC FY + E V ++ +P
Sbjct: 169 GWLHKQDS-SGMRLWKRRWFVLAD---YCLFYYKDSREEAVLGSIPLPSYVISPVAPEDR 224
Query: 338 INKETRIRAMDKDAKKRIHNFSVINPVPGQA--ITQIFAVDNREDLQKWMEAFWQ 390
I+++ +A+ + I+N S Q+ T F+ D +ED+ W+ A Q
Sbjct: 225 ISRKYSFKAVHTGMRALIYNSSTAGSQAEQSGMRTYYFSADTQEDMNAWVRAMNQ 279
>gi|32483410 vitamin D-binding protein precursor [Homo sapiens]
Length = 474
Score = 30.0 bits (66), Expect = 6.5
Identities = 17/68 (25%), Positives = 35/68 (51%), Gaps = 7/68 (10%)
Query: 158 ENVTIFNEAGPDFQIKVEVY-----SCCTE--ESSITNTPKKLAKKLKTSISKATGKKIS 210
++ T FN GP + ++ + C + E++ T KKLA++LK + AT +++
Sbjct: 380 DSTTCFNAKGPLLKKELSSFIDKGQELCADYSENTFTEYKKKLAERLKAKLPDATPTELA 439
Query: 211 SVLQEEDD 218
++ + D
Sbjct: 440 KLVNKHSD 447
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 30.0 bits (66), Expect = 6.5
Identities = 22/104 (21%), Positives = 46/104 (44%), Gaps = 11/104 (10%)
Query: 291 GFLNQQQMVEG------LISWRRLYCVLRGGKLYCFYSPEEIEAKVEPALVVPINKETRI 344
GFLN++ E SW +YCV+ ++ + + + + VP++ + +
Sbjct: 2202 GFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKTAASGIPYHSEVPVSLKEAV 2261
Query: 345 RAMDKDAKKRIHNFSV-INPVPGQAITQIFAVDNREDLQKWMEA 387
+ D KK+ H F + +N +F + E++ W++A
Sbjct: 2262 CEVALDYKKKKHVFKLRLN----DGNEYLFQAKDDEEMNTWIQA 2301
>gi|212549782 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 29.6 bits (65), Expect = 8.4
Identities = 57/273 (20%), Positives = 107/273 (39%), Gaps = 49/273 (17%)
Query: 34 MREGIWKLLSLSTQKDQVLHAVKNLMVCNARLMAYTSE---LQKLEEQIANQTGRCDVKF 90
M++ +WK + Q D + +K ++VC+++ S+ L+K +Q A +
Sbjct: 1127 MKKKLWKFVD--DQLDYLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSV 1184
Query: 91 ESKERTACKGKIAISDIRIPLMWKDSDHFSN----KERSRRYAIFCLFKMGANVFDTDVV 146
++ R K K++ S+ D H+ + K+ Y N + V
Sbjct: 1185 DNSNRELLKEKLSKSE--------DPVHYKSLVGCKKSEENY-------QDQNNSSINTV 1229
Query: 147 NVD-KTITDICFENVTIFNEAGPDFQIKVEVYSCCTEESSITNTPKKLAKKLKTSISKAT 205
D K +ICF+N+ N + ++V S TPK K +SI A
Sbjct: 1230 KHDIKKNFNICFDNIK--NSQSEERSLEVHCPS----------TPKS-EKNEGSSIEDAQ 1276
Query: 206 GKKISSVLQEEDDEMCLLLSSAVFGVKYNLLAHTTL--TLESAEDSFKTHNLSINGNEES 263
+ +++ E E +L + +NL++ + +S + S+N E+S
Sbjct: 1277 TSQHATLKPERSFE--ILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDSSVNCTEKS 1334
Query: 264 SFWL-----PLYGNMCCRLVAQPACMAEDAFAG 291
+ L L + C + PAC E+ +G
Sbjct: 1335 EWELKTPEKQLLETLKCESI--PACTTEELVSG 1365
>gi|6912288 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 29.6 bits (65), Expect = 8.4
Identities = 57/273 (20%), Positives = 107/273 (39%), Gaps = 49/273 (17%)
Query: 34 MREGIWKLLSLSTQKDQVLHAVKNLMVCNARLMAYTSE---LQKLEEQIANQTGRCDVKF 90
M++ +WK + Q D + +K ++VC+++ S+ L+K +Q A +
Sbjct: 1127 MKKKLWKFVD--DQLDYLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSV 1184
Query: 91 ESKERTACKGKIAISDIRIPLMWKDSDHFSN----KERSRRYAIFCLFKMGANVFDTDVV 146
++ R K K++ S+ D H+ + K+ Y N + V
Sbjct: 1185 DNSNRELLKEKLSKSE--------DPVHYKSLVGCKKSEENY-------QDQNNSSINTV 1229
Query: 147 NVD-KTITDICFENVTIFNEAGPDFQIKVEVYSCCTEESSITNTPKKLAKKLKTSISKAT 205
D K +ICF+N+ N + ++V S TPK K +SI A
Sbjct: 1230 KHDIKKNFNICFDNIK--NSQSEERSLEVHCPS----------TPKS-EKNEGSSIEDAQ 1276
Query: 206 GKKISSVLQEEDDEMCLLLSSAVFGVKYNLLAHTTL--TLESAEDSFKTHNLSINGNEES 263
+ +++ E E +L + +NL++ + +S + S+N E+S
Sbjct: 1277 TSQHATLKPERSFE--ILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDSSVNCTEKS 1334
Query: 264 SFWL-----PLYGNMCCRLVAQPACMAEDAFAG 291
+ L L + C + PAC E+ +G
Sbjct: 1335 EWELKTPEKQLLETLKCESI--PACTTEELVSG 1365
>gi|212549532 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 29.6 bits (65), Expect = 8.4
Identities = 57/273 (20%), Positives = 107/273 (39%), Gaps = 49/273 (17%)
Query: 34 MREGIWKLLSLSTQKDQVLHAVKNLMVCNARLMAYTSE---LQKLEEQIANQTGRCDVKF 90
M++ +WK + Q D + +K ++VC+++ S+ L+K +Q A +
Sbjct: 1127 MKKKLWKFVD--DQLDYLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSV 1184
Query: 91 ESKERTACKGKIAISDIRIPLMWKDSDHFSN----KERSRRYAIFCLFKMGANVFDTDVV 146
++ R K K++ S+ D H+ + K+ Y N + V
Sbjct: 1185 DNSNRELLKEKLSKSE--------DPVHYKSLVGCKKSEENY-------QDQNNSSINTV 1229
Query: 147 NVD-KTITDICFENVTIFNEAGPDFQIKVEVYSCCTEESSITNTPKKLAKKLKTSISKAT 205
D K +ICF+N+ N + ++V S TPK K +SI A
Sbjct: 1230 KHDIKKNFNICFDNIK--NSQSEERSLEVHCPS----------TPKS-EKNEGSSIEDAQ 1276
Query: 206 GKKISSVLQEEDDEMCLLLSSAVFGVKYNLLAHTTL--TLESAEDSFKTHNLSINGNEES 263
+ +++ E E +L + +NL++ + +S + S+N E+S
Sbjct: 1277 TSQHATLKPERSFE--ILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDSSVNCTEKS 1334
Query: 264 SFWL-----PLYGNMCCRLVAQPACMAEDAFAG 291
+ L L + C + PAC E+ +G
Sbjct: 1335 EWELKTPEKQLLETLKCESI--PACTTEELVSG 1365
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,328,211
Number of Sequences: 37866
Number of extensions: 1015360
Number of successful extensions: 3026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2992
Number of HSP's gapped (non-prelim): 39
length of query: 609
length of database: 18,247,518
effective HSP length: 108
effective length of query: 501
effective length of database: 14,157,990
effective search space: 7093152990
effective search space used: 7093152990
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.