Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 253970489
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
(714 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 1495 0.0
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 1461 0.0
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 608 e-174
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 360 3e-99
gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens] 201 1e-51
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 187 2e-47
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 182 7e-46
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 179 8e-45
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 163 5e-40
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 152 1e-36
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 140 5e-33
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 140 5e-33
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 135 1e-31
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 135 1e-31
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 103 7e-22
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 103 7e-22
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 100 4e-21
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 76 9e-14
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 67 6e-11
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 59 2e-08
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 57 6e-08
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 57 8e-08
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 51 3e-06
gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens] 47 6e-05
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 45 2e-04
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 45 2e-04
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 45 2e-04
gi|168229156 NFKB activating protein [Homo sapiens] 35 0.24
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 34 0.54
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo... 34 0.54
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 1495 bits (3871), Expect = 0.0
Identities = 714/714 (100%), Positives = 714/714 (100%)
Query: 1 MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPRE 60
MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPRE
Sbjct: 1 MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPRE 60
Query: 61 FWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDK 120
FWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDK
Sbjct: 61 FWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDK 120
Query: 121 VAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLAC 180
VAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLAC
Sbjct: 121 VAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLAC 180
Query: 181 ARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEK 240
ARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEK
Sbjct: 181 ARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEK 240
Query: 241 GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEKSKRVQPQISWNQGIDL 300
GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEKSKRVQPQISWNQGIDL
Sbjct: 241 GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEKSKRVQPQISWNQGIDL 300
Query: 301 WWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDF 360
WWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDF
Sbjct: 301 WWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDF 360
Query: 361 HAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFY 420
HAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFY
Sbjct: 361 HAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFY 420
Query: 421 TAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQ 480
TAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQ
Sbjct: 421 TAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQ 480
Query: 481 TETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMR 540
TETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMR
Sbjct: 481 TETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMR 540
Query: 541 TVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESA 600
TVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESA
Sbjct: 541 TVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESA 600
Query: 601 LVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDY 660
LVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDY
Sbjct: 601 LVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDY 660
Query: 661 IQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADPSVISHLFSHRCLTIQ 714
IQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADPSVISHLFSHRCLTIQ
Sbjct: 661 IQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADPSVISHLFSHRCLTIQ 714
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 1461 bits (3782), Expect = 0.0
Identities = 701/714 (98%), Positives = 701/714 (98%), Gaps = 13/714 (1%)
Query: 1 MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPRE 60
MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPRE
Sbjct: 1 MGLPEERVRSGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPRE 60
Query: 61 FWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDK 120
FWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDK
Sbjct: 61 FWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDK 120
Query: 121 VAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLAC 180
VAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLAC
Sbjct: 121 VAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLAC 180
Query: 181 ARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEK 240
ARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEK
Sbjct: 181 ARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEK 240
Query: 241 GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEKSKRVQPQISWNQGIDL 300
GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQ ISWNQGIDL
Sbjct: 241 GFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQ-------------ISWNQGIDL 287
Query: 301 WWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDF 360
WWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDF
Sbjct: 288 WWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDF 347
Query: 361 HAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFY 420
HAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFY
Sbjct: 348 HAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFY 407
Query: 421 TAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQ 480
TAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQ
Sbjct: 408 TAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQ 467
Query: 481 TETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMR 540
TETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMR
Sbjct: 468 TETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPWPGIMR 527
Query: 541 TVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESA 600
TVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESA
Sbjct: 528 TVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESA 587
Query: 601 LVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDY 660
LVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDY
Sbjct: 588 LVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDY 647
Query: 661 IQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADPSVISHLFSHRCLTIQ 714
IQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADPSVISHLFSHRCLTIQ
Sbjct: 648 IQNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADPSVISHLFSHRCLTIQ 701
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 608 bits (1568), Expect = e-174
Identities = 320/709 (45%), Positives = 429/709 (60%), Gaps = 58/709 (8%)
Query: 8 VRSGSGSRGQEEAGAGGRARSWSPP----PEVSRSAHVPSLQRYRELHRRSVEEPREFWG 63
+R SG + G R+ S P P V+ +A P Y L ++ EP FWG
Sbjct: 17 LRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPG--SYPALSAQAAREPAAFWG 74
Query: 64 DIAKE-FYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDKVA 122
+A++ W TP ++ D + GKI W G N+ N LD+ H +K + VA
Sbjct: 75 PLARDTLVWDTPY---HTVWDCDFSTGKI--GWFLGGQLNVSVNCLDQ--HVRKSPESVA 127
Query: 123 FYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLACAR 182
WE +EPG +ITY +LL C+ +N L++ G+ +GDRVAIYMP+ P V AMLACAR
Sbjct: 128 LIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACAR 187
Query: 183 IGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEKGF 242
IGA+H+++FAGFS+ESL RI D+ C ++IT + RG ++V LK++ DEA++ C
Sbjct: 188 IGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHC----- 242
Query: 243 PVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEKSKRVQPQISWNQGIDLWW 302
P ++V H ++ MGD +D+
Sbjct: 243 PTVQHVLVAHRTDNKVHMGD-----------------------------------LDVPL 267
Query: 303 HELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHA 362
+ M + C PE +ED LF+LYTSGSTG PKG+VHT GY+LY A T K VFD
Sbjct: 268 EQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQP 327
Query: 363 EDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTA 422
D+F C ADIGWITGHSYV YGPL NGATSVLFE P YP+ R W V++ K+ +FY A
Sbjct: 328 GDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGA 387
Query: 423 PTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTE 482
PTA+RLL+K+GD V K+ R+SL+ LG+VGEPIN EAW W HRVVG RC +VDT+WQTE
Sbjct: 388 PTAVRLLLKYGDAWVKKYDRSSLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQTE 447
Query: 483 TGGHMLTPLPG--ATPMKPGSATFPFFGVAPAILNESGEELEG-EAEGYLVFKQPWPGIM 539
TGG + P P + P A PFFG+ P +++E G +EG G L Q WPG+
Sbjct: 448 TGGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQAWPGMA 507
Query: 540 RTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVES 599
RT+YG+H+RF YFK +PGYY TGDG R + GYY ITGR+DD++N+SGH L TAE+E
Sbjct: 508 RTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEIED 567
Query: 600 ALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPD 659
A+ +H AV E+AV+G+PH +KGE + F+ + D S + +ELK + KI A PD
Sbjct: 568 AIADHPAVPESAVIGYPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVPD 627
Query: 660 YIQNAPGLPKTRSGKIMRRVLRKIAQND-HDLGDMSTVADPSVISHLFS 707
I LPKTRSGK+MRR+LRKI ++ +LGD +T+ DPS+I+ + S
Sbjct: 628 EILVVKRLPKTRSGKVMRRLLRKIITSEAQELGDTTTLEDPSIIAEILS 676
>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
sapiens]
Length = 686
Score = 360 bits (923), Expect = 3e-99
Identities = 237/702 (33%), Positives = 344/702 (49%), Gaps = 72/702 (10%)
Query: 13 GSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYRELHRRSVEEPREFWGDIAKEFYWK 72
G RG G GGR R+ S Y+ SV +P FWG A++ W
Sbjct: 41 GPRG----GLGGRG---------CRALSSGSGSEYKTHFAASVTDPERFWGKAAEQISWY 87
Query: 73 TPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGE 132
P + T+ W NICYN +DR++ K GDK+A ++
Sbjct: 88 KPWTKTLENKHSPSTR------WFVEGMLNICYNAVDRHIENGK-GDKIAIIYDSPVTNT 140
Query: 133 TTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFA 192
TY ++L QV + + VL K GI+KGD V IYMPMIP+ + MLACARIGA+HS++F
Sbjct: 141 KATFTYKEVLEQVSKLAGVLVKHGIKKGDTVVIYMPMIPQAMYTMLACARIGAIHSLIFG 200
Query: 193 GFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKH 252
GF+S+ L RI +++T + V L +EAL+ Q K
Sbjct: 201 GFASKELSSRIDHVKPKVVVTASFGIEPGRRVEYVPLVEEALKIGQHK------------ 248
Query: 253 LGRAELGMGDSTSQSPPIKRSCPDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEA-GD 311
PD K+ ++ + G DL W E M +A
Sbjct: 249 ----------------------PD---KILIYNRPNMEAVPLAPGRDLDWDEEMAKAQSH 283
Query: 312 ECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTAD 371
+C P +E PL+ILYTSG+TG PKGV+ GGY + + + ++ +V+W +D
Sbjct: 284 DCVPVL--SEHPLYILYTSGTTGLPKGVIRPTGGYAVMLHWSMSSIYGLQPGEVWWAASD 341
Query: 372 IGWITGHSYVTYGPLANGATSVLFEGIPT-YPDVNRLWSIVDKYKVTKFYTAPTAIRLLM 430
+GW+ GHSY+ YGPL +G T+VL+EG P PD + ++ ++ V +TAPTAIR +
Sbjct: 342 LGWVVGHSYICYGPLLHGNTTVLYEGKPVGTPDAGAYFRVLAEHGVAALFTAPTAIRAIR 401
Query: 431 KF--GDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHML 488
+ G ++S + L GE + E W V R P++D +WQTETG +
Sbjct: 402 QQDPGAALGKQYSLTRFKTLFVAGERCDVETLEWSKNVF---RVPVLDHWWQTETGSPIT 458
Query: 489 TPLPGATPMK---PGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQPW-PGIMRTVYG 544
G K PG A G IL+++ ++L+ G +V K P PG ++
Sbjct: 459 ASCVGLGNSKTPPPGQAGKSVPGYNVMILDDNMQKLKARCLGNIVVKLPLPPGAFSGLWK 518
Query: 545 NHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEH 604
N E F+ YF+KFPGYY T D D++GY ++ R+DD++NV+GH +S +E +++ H
Sbjct: 519 NQEAFKHLYFEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISAGAIEESILSH 578
Query: 605 EAVAEAAVVGHPHPVKGEC-LYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQN 663
VA+ AVVG P+KG L V D + ++ EE+ K +R+ IGP+A
Sbjct: 579 GTVADCAVVGKEDPLKGHVPLALCVLRKDINATEEQVLEEIVKHVRQNIGPVAAFRNAVF 638
Query: 664 APGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADPSVISHL 705
LPKTRSGKI R L I N ST+ DPS+ H+
Sbjct: 639 VKQLPKTRSGKIPRSALSAIV-NGKPYKITSTIEDPSIFGHV 679
>gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens]
Length = 672
Score = 201 bits (512), Expect = 1e-51
Identities = 169/652 (25%), Positives = 286/652 (43%), Gaps = 63/652 (9%)
Query: 43 SLQRYRELHRRSVEEPREFWGDIAKEFYWKTPCPGPFLRYN--FDVTKGKIFI-EWMKGA 99
+L+ Y +L+ SVE +FW + +WK Y+ D +KG + EW KG+
Sbjct: 43 ALESYDDLYHWSVESYSDFWAE-----FWKFSGIVFSRVYDEVVDTSKGIADVPEWFKGS 97
Query: 100 TTNICYNVLDRNVHEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQK 159
N N+L K D+VA Y E ++T+ +L +V F+ +RK G++K
Sbjct: 98 RLNYAENLL-----RHKENDRVALYIAREGKEEIVKVTFEELRQEVALFAAAMRKMGVKK 152
Query: 160 GDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF-Y 218
GDRV Y+P V AMLA A IGA+ S F + +R L+ + +A Y
Sbjct: 153 GDRVVGYLPNSEHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVY 212
Query: 219 RGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQ 278
G++ ++++L KG P +VV P V
Sbjct: 213 NGKEHNHMEKLQQVV------KGLPDLKKVVV-----------------------IPYVS 243
Query: 279 GKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKG 338
+ ++ + +D + E + E E PLFI+++SG+TG PK
Sbjct: 244 SRENIDLSKIPNSVF----LDDFLATGTSEQAPQLEFEQLPFSHPLFIMFSSGTTGAPKC 299
Query: 339 VVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGI 398
+VH+ GG ++ + + D+ C +GW+ + V+ LA GA VL++G
Sbjct: 300 MVHSAGGTLIQHLKEHLLHGNMTSSDILLCYTTVGWMMWNWMVSL--LATGAAMVLYDGS 357
Query: 399 PTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPE 458
P P N LW +VD+ +T T + +L + +PV HS L + + G P+ +
Sbjct: 358 PLVPTPNVLWDLVDRIGITVLVTGAKWLSVLEEKAMKPVETHSLQMLHTILSTGSPLKAQ 417
Query: 459 AWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPG---ATPMKPGSATFPFFGVAPAILN 515
++ + +R + + G +++ G + P+ G G+A N
Sbjct: 418 SYEYVYRCIKSS-----ILLGSISGGTDIISCFMGHNFSLPVYKGEIQARNLGMAVEAWN 472
Query: 516 ESGEELEGEAEGYLVFKQPWPGIMRTVYGNHE---RFETTYFKKFPGYYVTGDGCQ-RDQ 571
E G+ + GE+ G LV +P P T + N E ++ YF KFPG + GD C+ +
Sbjct: 473 EEGKAVWGES-GELVCTKPIP-CQPTHFWNDENGNKYRKAYFSKFPGIWAHGDYCRINPK 530
Query: 572 DGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLC 631
G + GR D LN +G ++E+ + + E V ++ V + + E + F+ +
Sbjct: 531 TGGIVMLGRSDGTLNPNGVRFGSSEIYNIVESFEEVEDSLCVPQYNKYREERVILFLKMA 590
Query: 632 DGHTFSPKLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRKI 683
GH F P L + ++ IR + P I G+P T +GK + +++I
Sbjct: 591 SGHAFQPDLVKRIRDAIRMGLSARHVPSLILETKGIPYTLNGKKVEVAVKQI 642
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 187 bits (476), Expect = 2e-47
Identities = 169/589 (28%), Positives = 265/589 (44%), Gaps = 77/589 (13%)
Query: 102 NICYNVLDRNVHEKKLGDKVA--FYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GIQ 158
N +VLD+ ++K G++ A W N G+ + ++ +L + +NVL K G+Q
Sbjct: 53 NFAADVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQ 112
Query: 159 KGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFY 218
+GDR+A+ +P IPE + +AC R G I+F + + L D Y
Sbjct: 113 RGDRLAVILPRIPEWWLVNVACIRTG----IIFMPGTIQ-------------LTAKDILY 155
Query: 219 RGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQ 278
R L+ + K CIV + I CPD++
Sbjct: 156 R--------------LRASKAK------CIVASE---------EVAPAVESIVLECPDLK 186
Query: 279 GKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKG 338
KL V PQ SWN + + EL Q A +E +++P+ I +TSG+TG PK
Sbjct: 187 TKLL-----VSPQ-SWNGWLS--FQELFQFASEEHSCVETGSQEPMTIYFTSGTTGFPKM 238
Query: 339 VVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGI 398
H+ + +Y D + D+ W +D GW+ + GA +F
Sbjct: 239 AQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGAC--VFVHR 296
Query: 399 PTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPE 458
D + + Y +T + PT R+L++ + + ++ SL+ T GEP+NPE
Sbjct: 297 MAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQ---KDLKRYKFKSLRHCLTGGEPLNPE 353
Query: 459 AWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNESG 518
+ G + + + + QTE G M+ +KPGS I++E+G
Sbjct: 354 VLEQWRVQTGLE---LYEGYGQTEVG--MICANQKGQEIKPGSMGKGMLPYDVQIIDENG 408
Query: 519 EELEGEAEGYLVFK----QPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGY 574
L EG + + +P+ + V N ++ T F YVTGD D DGY
Sbjct: 409 NVLPPGKEGEIALRLKPTRPFCFFSKYV-DNPQKTAATIRGDF---YVTGDRGVMDSDGY 464
Query: 575 YWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTL-CDG 633
+W GR DD++ SG+ + EVESAL+EH AV E+AVV P ++GE + FV L
Sbjct: 465 FWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPF 524
Query: 634 HTFSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681
+++P KLT EL+ +++ P P ++ LPKT +GKI R VLR
Sbjct: 525 KSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLR 573
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 182 bits (463), Expect = 7e-46
Identities = 160/591 (27%), Positives = 261/591 (44%), Gaps = 79/591 (13%)
Query: 102 NICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GI 157
N +VLD+ ++K G K AF+W N GE + ++ +L +F+N+L + +
Sbjct: 59 NFAKDVLDQWTDKEKAGKKPSNPAFWWI-NRNGEEMRWSFEELGSLSRKFANILSEACSL 117
Query: 158 QKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF 217
Q+GDRV + +P +PE +A +AC R G + + + + R+ S + +IT D
Sbjct: 118 QRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDV- 176
Query: 218 YRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277
L D KC+ + ++V R +
Sbjct: 177 --------LAPAVDAVASKCEN----LHSKLIVSENSR--------------------EG 204
Query: 278 QGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPK 337
G LKE LM+ A D + + I +TSG++G PK
Sbjct: 205 WGNLKE---------------------LMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPK 243
Query: 338 GVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEG 397
HT + L ++ ++ D DV W T+D GW + P GA V
Sbjct: 244 MTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGAC-VFTHH 302
Query: 398 IPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINP 457
+P + + L ++ KY +T F +APT R+L++ +T + SL+ + GEPI P
Sbjct: 303 LPRFEPTSILQTL-SKYPITVFCSAPTVYRMLVQ---NDITSYKFKSLKHCVSAGEPITP 358
Query: 458 EAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNES 517
+ + G I + + QTET ++ +KPGS P I++ +
Sbjct: 359 DVTEKWRNKTGLD---IYEGYGQTETV--LICGNFKGMKIKPGSMGKPSPAFDVKIVDVN 413
Query: 518 GEEL----EGEAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDG 573
G L EG+ ++ +P+ G+ N + +T F Y+TGD D+DG
Sbjct: 414 GNVLPPGQEGDIGIQVLPNRPF-GLFTHYVDNPSKTASTLRGNF---YITGDRGYMDKDG 469
Query: 574 YYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDG 633
Y+W R DD++ SG+ + EVE+AL EH +VAE+AVV P P++GE + FV L
Sbjct: 470 YFWFVARADDVILSSGYRIGPFEVENALNEHPSVAESAVVSSPDPIRGEVVKAFVVLNPD 529
Query: 634 HTF--SPKLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRK 682
+ +L +E+++ +++ P P ++ LPKT SGK R LRK
Sbjct: 530 YKSHDQEQLIKEIQEHVKKTTAPYKYPRKVEFIQELPKTISGKTKRNELRK 580
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 179 bits (454), Expect = 8e-45
Identities = 162/589 (27%), Positives = 262/589 (44%), Gaps = 78/589 (13%)
Query: 102 NICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GI 157
N ++VLD ++ G + AF+W N G + ++ +L Q + +NVL G+
Sbjct: 54 NFAHDVLDVWSRLEEAGHRPPNPAFWWV-NGTGAEIKWSFEELGKQSRKAANVLGGACGL 112
Query: 158 QKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF 217
Q GDR+ + +P +PE + +AC R G + + + L R+ S +IT+D+
Sbjct: 113 QPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSL 172
Query: 218 YRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277
+ I CP +
Sbjct: 173 ----------------------------------------------APRVDAISAECPSL 186
Query: 278 QGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPK 337
Q KL + W L + EL++EA E + DPL I +TSG+TG PK
Sbjct: 187 QTKLLVSDSS---RPGW-----LNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPK 238
Query: 338 GVVHTVGGYML-YVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFE 396
V H+ Y L +VA+ ++V D+FW T D GW+ ++ + NG+ + E
Sbjct: 239 MVEHSQSSYGLGFVASGRRWVA-LTESDIFWNTTDTGWVKA-AWTLFSAWPNGSCIFVHE 296
Query: 397 GIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPIN 456
+P D + + + K+ +T PT RLL++ E +T++ SL+ T GE +N
Sbjct: 297 -LPRV-DAKVILNTLSKFPITTLCCVPTIFRLLVQ---EDLTRYQFQSLRHCLTGGEALN 351
Query: 457 PEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNE 516
P+ + G + + + + Q+ET ++ P +K GS I+++
Sbjct: 352 PDVREKWKHQTGVE---LYEGYGQSETV--VICANPKGMKIKSGSMGKASPPYDVQIVDD 406
Query: 517 SGEELEGEAEGYLV--FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGY 574
G L EG + + P Y ++ E T + +Y+TGD + D+DGY
Sbjct: 407 EGNVLPPGEEGNVAVRIRPTRPFCFFNCYLDNP--EKTAASEQGDFYITGDRARMDKDGY 464
Query: 575 YWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGH 634
+W GR DD++N S + + EVESAL EH AV E+AVV P P++GE + F+ L +
Sbjct: 465 FWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAY 524
Query: 635 -TFSPK-LTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681
+ P+ LT EL++ ++ P P + LPKT SGKI R LR
Sbjct: 525 SSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLR 573
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 163 bits (413), Expect = 5e-40
Identities = 169/635 (26%), Positives = 268/635 (42%), Gaps = 82/635 (12%)
Query: 59 REFWGDIAKEFYWKTPCPGPFLRYNFDVTKGKIFIEWMKGATTNICYNVLD---RNVHEK 115
R WG I K F+ P P + + ++ N VLD + E
Sbjct: 8 RTLWG-IHKSFHNIHPAPSQLRCRSLSEFGAPRWNDYEVPEEFNFASYVLDYWAQKEKEG 66
Query: 116 KLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GIQKGDRVAIYMPMIPELV 174
K G AF+W N G+ + ++ ++ + +NV + G+Q+GD +A+ +P +PE
Sbjct: 67 KRGPNPAFWWV-NGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHLALMLPRVPEWW 125
Query: 175 VAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEAL 234
+ + C R G I+F + LL D YR L
Sbjct: 126 LVAVGCMRTG----IIFI-------------PATILLKAKDILYR--------------L 154
Query: 235 QKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEKSKRVQPQISW 294
Q + KG + + L S+ I CP ++ KL + W
Sbjct: 155 QLSKAKGI-----VTIDALA----------SEVDSIASQCPSLKTKLLVSDHSRE---GW 196
Query: 295 NQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTF 354
L + L++ A E DP+ I +TSG+TG PK H+ G +
Sbjct: 197 -----LDFRSLVKSASPEHTCVKSKTLDPMVIFFTSGTTGFPKMAKHSHGLALQPSFPGS 251
Query: 355 KYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKY 414
+ + DV WC +D GWI + P G T V +P + D + + KY
Sbjct: 252 RKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTAGCT-VFIHHLPQF-DTKVIIQTLLKY 309
Query: 415 KVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPI 474
+ F+ + R++++ + T +L+ T GE + P+ + R G +
Sbjct: 310 PINHFWGVSSIYRMILQ---QDFTSIRFPALEHCYTGGEVVLPKDQEEWKRRTGLL---L 363
Query: 475 VDTFWQTETGGHMLTPLPGATPMKPG---SATFPFFGVAPAILNESGEELEGEAEGYLVF 531
+ + Q+ETG ++ +KPG AT P+ ++++ G L EG +
Sbjct: 364 YENYGQSETG--LICATYWGMKIKPGFMGKATPPY---DVQVIDDKGSILPPNTEGNIGI 418
Query: 532 --KQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSG 589
K P + Y E T + +Y TGD + D++GY GR DD++N SG
Sbjct: 419 RIKPVRPVSLFMCYEGDP--EKTAKVECGDFYNTGDRGKMDEEGYICFLGRSDDIINASG 476
Query: 590 HLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPK--LTEELKKQ 647
+ + AEVESALVEH AVAE+AVVG P P++GE + F+ L K LT+EL++
Sbjct: 477 YRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQH 536
Query: 648 IREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLRK 682
++ P P ++ LPKT +GKI R+ LRK
Sbjct: 537 VKSVTAPYKYPRKVEFVSELPKTITGKIERKELRK 571
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 152 bits (383), Expect = 1e-36
Identities = 152/595 (25%), Positives = 249/595 (41%), Gaps = 84/595 (14%)
Query: 99 ATTNICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ 155
A N +VLD +K G ++ A +W N G+ + +L Q +NVL
Sbjct: 42 AKFNFASDVLDHWADMEKAGKRLPSPALWWV-NGKGKELMWNFRELSENSQQAANVLSGA 100
Query: 156 -GIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITT 214
G+Q+GDRVA+ +P +PE + +L C R G + S + R+ S ++
Sbjct: 101 CGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA- 159
Query: 215 DAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSC 274
DE +Q+ + C
Sbjct: 160 ---------------GDEVIQEVDT------------------------------VASEC 174
Query: 275 PDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTG 334
P ++ KL K +++ + L+ EA +++ I +TSG++G
Sbjct: 175 PSLRIKLLVSEKSCDGWLNFKK--------LLNEASTTHHCVETGSQEASAIYFTSGTSG 226
Query: 335 KPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVL 394
PK H+ L + A D+ W +D GWI P A GA + +
Sbjct: 227 LPKMAEHSYSSLGLKAKMDAGWT-GLQASDIMWTISDTGWILNILCSLMEPWALGACTFV 285
Query: 395 FEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEP 454
+P + D + + Y + AP R+L++ + ++ + LQ TVGE
Sbjct: 286 HL-LPKF-DPLVILKTLSSYPIKSMMGAPIVYRMLLQ---QDLSSYKFPHLQNCVTVGES 340
Query: 455 INPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGAT-PMKPGSATFPFFGVAPA- 512
+ PE + G I +++ QTETG LT + T +KPG + G A +
Sbjct: 341 LLPETLENWRAQTGLD---IRESYGQTETG---LTCMVSKTMKIKPG-----YMGTAASC 389
Query: 513 ----ILNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQ 568
I+++ G L EG + + + G + + T +++ GD
Sbjct: 390 YDVQIIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWLLGDRGI 449
Query: 569 RDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYCFV 628
+D+DGY+ GR DD++N SG+ + +EVE+AL+EH AV E AV+ P PV+GE + FV
Sbjct: 450 KDEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFV 509
Query: 629 TLCDGH-TFSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681
L + P +LT+EL++ ++ P P I+ LPKT +GKI R LR
Sbjct: 510 VLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLR 564
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 140 bits (352), Expect = 5e-33
Identities = 147/597 (24%), Positives = 243/597 (40%), Gaps = 88/597 (14%)
Query: 99 ATTNICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ 155
A N +VLD +K G ++ A +W N G+ + +L Q +N+L
Sbjct: 42 AKFNFASDVLDHWADMEKAGKRLPSPALWWV-NGKGKELMWNFRELSENSQQAANILSGA 100
Query: 156 -GIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITT 214
G+Q+GDRVA+ +P +PE + +L C R G + S + R+ S ++
Sbjct: 101 CGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA- 159
Query: 215 DAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSC 274
DE +Q+ + C
Sbjct: 160 ---------------GDEVIQEVDT------------------------------VASEC 174
Query: 275 PDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTG 334
P ++ KL K +++ + L+ EA +++ I +TSG++G
Sbjct: 175 PSLRIKLLVSEKSCDGWLNFKK--------LLNEASTTHHCVETGSQEASAIYFTSGTSG 226
Query: 335 KPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVL 394
PK H+ L + A D+ W +D GWI G L T
Sbjct: 227 LPKMAEHSYSSLGLKAKMDAGWT-GLQASDIMWTISDTGWILN----ILGSLLESWTLGA 281
Query: 395 FEGIPTYPDVNRLWSI--VDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVG 452
+ P + L + + Y + AP R+L++ + ++ + LQ G
Sbjct: 282 CTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQ---QDLSSYKFPHLQNCLAGG 338
Query: 453 EPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGAT-PMKPGSATFPFFGVAP 511
E + PE + G I + + QTETG LT + T +KPG + G A
Sbjct: 339 ESLLPETLENWRAQTGLD---IREFYGQTETG---LTCMVSKTMKIKPG-----YMGTAA 387
Query: 512 A-----ILNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDG 566
+ ++++ G L EG + + + G E + T +++ GD
Sbjct: 388 SCYDVQVIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDR 447
Query: 567 CQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYC 626
+D+DGY+ GR DD++N SG+ + +EVE+AL++H AV E AV+ P PV+GE +
Sbjct: 448 GIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKA 507
Query: 627 FVTLCDGH-TFSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681
FV L + P +LT+EL++ ++ P P I+ LPKT +GKI R LR
Sbjct: 508 FVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 564
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 140 bits (352), Expect = 5e-33
Identities = 147/597 (24%), Positives = 243/597 (40%), Gaps = 88/597 (14%)
Query: 99 ATTNICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ 155
A N +VLD +K G ++ A +W N G+ + +L Q +N+L
Sbjct: 42 AKFNFASDVLDHWADMEKAGKRLPSPALWWV-NGKGKELMWNFRELSENSQQAANILSGA 100
Query: 156 -GIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITT 214
G+Q+GDRVA+ +P +PE + +L C R G + S + R+ S ++
Sbjct: 101 CGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA- 159
Query: 215 DAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSC 274
DE +Q+ + C
Sbjct: 160 ---------------GDEVIQEVDT------------------------------VASEC 174
Query: 275 PDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTG 334
P ++ KL K +++ + L+ EA +++ I +TSG++G
Sbjct: 175 PSLRIKLLVSEKSCDGWLNFKK--------LLNEASTTHHCVETGSQEASAIYFTSGTSG 226
Query: 335 KPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVL 394
PK H+ L + A D+ W +D GWI G L T
Sbjct: 227 LPKMAEHSYSSLGLKAKMDAGWT-GLQASDIMWTISDTGWILN----ILGSLLESWTLGA 281
Query: 395 FEGIPTYPDVNRLWSI--VDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVG 452
+ P + L + + Y + AP R+L++ + ++ + LQ G
Sbjct: 282 CTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQ---QDLSSYKFPHLQNCLAGG 338
Query: 453 EPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGAT-PMKPGSATFPFFGVAP 511
E + PE + G I + + QTETG LT + T +KPG + G A
Sbjct: 339 ESLLPETLENWRAQTGLD---IREFYGQTETG---LTCMVSKTMKIKPG-----YMGTAA 387
Query: 512 A-----ILNESGEELEGEAEGYLVFKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDG 566
+ ++++ G L EG + + + G E + T +++ GD
Sbjct: 388 SCYDVQVIDDKGNVLPPGTEGDIGIRVKPIRPIGIFSGYVENPDKTAANIRGDFWLLGDR 447
Query: 567 CQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECLYC 626
+D+DGY+ GR DD++N SG+ + +EVE+AL++H AV E AV+ P PV+GE +
Sbjct: 448 GIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKA 507
Query: 627 FVTLCDGH-TFSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681
FV L + P +LT+EL++ ++ P P I+ LPKT +GKI R LR
Sbjct: 508 FVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 564
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 135 bits (340), Expect = 1e-31
Identities = 148/599 (24%), Positives = 241/599 (40%), Gaps = 98/599 (16%)
Query: 99 ATTNICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ 155
A N +VLD +K G ++ A +W N G+ + +L Q +NVL
Sbjct: 42 AKFNFASDVLDHWADMEKAGKRLPSPALWWV-NGKGKELMWNFRELSENSQQAANVLSGA 100
Query: 156 -GIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITT 214
G+Q+GDRVA+ +P +PE + +L C R G + S + R+ S ++
Sbjct: 101 CGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA- 159
Query: 215 DAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSC 274
DE +Q+ + C
Sbjct: 160 ---------------GDEVIQEVDT------------------------------VASEC 174
Query: 275 PDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTG 334
P ++ KL K +++ + L+ EA +++ I +TSG++G
Sbjct: 175 PSLRIKLLVSEKSCDGWLNFKK--------LLNEASTTHHCVETGSQEASAIYFTSGTSG 226
Query: 335 KPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVL 394
PK H+ L + A D+ W +D GWI G L T
Sbjct: 227 LPKMAEHSYSSLGLKAKMDAGWT-GLQASDIMWTISDTGWILN----ILGSLLESWTLGA 281
Query: 395 FEGIPTYPDVNRLWSI--VDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVG 452
+ P + L + + Y + AP R+L++ + ++ + LQ G
Sbjct: 282 CTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQ---QDLSSYKFPHLQNCLAGG 338
Query: 453 EPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGAT-PMKPGSATFPFFGVAP 511
E + PE + G I + + QTETG LT + T +KPG + G A
Sbjct: 339 ESLLPETLENWRAQTGLD---IREFYGQTETG---LTCMVSKTMKIKPG-----YMGTAA 387
Query: 512 AILNES------GEELEGEAEGYLVFKQPWPGIMRTVY-GNHERFETTYFKKFPGYYVTG 564
+ + G G+ + G M + G+ E + T +++ G
Sbjct: 388 SCYDVQVIAFVHGSPRAGDLG--------FAGTMTLSFCGHQENPDKTAANIRGDFWLLG 439
Query: 565 DGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECL 624
D +D+DGY+ GR DD++N SG+ + +EVE+AL++H AV E AV+ P PV+GE +
Sbjct: 440 DRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVV 499
Query: 625 YCFVTLCDGH-TFSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681
FV L + P +LT+EL++ ++ P P I+ LPKT +GKI R LR
Sbjct: 500 KAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 135 bits (340), Expect = 1e-31
Identities = 148/599 (24%), Positives = 241/599 (40%), Gaps = 98/599 (16%)
Query: 99 ATTNICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ 155
A N +VLD +K G ++ A +W N G+ + +L Q +NVL
Sbjct: 42 AKFNFASDVLDHWADMEKAGKRLPSPALWWV-NGKGKELMWNFRELSENSQQAANVLSGA 100
Query: 156 -GIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITT 214
G+Q+GDRVA+ +P +PE + +L C R G + S + R+ S ++
Sbjct: 101 CGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVA- 159
Query: 215 DAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSC 274
DE +Q+ + C
Sbjct: 160 ---------------GDEVIQEVDT------------------------------VASEC 174
Query: 275 PDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTG 334
P ++ KL K +++ + L+ EA +++ I +TSG++G
Sbjct: 175 PSLRIKLLVSEKSCDGWLNFKK--------LLNEASTTHHCVETGSQEASAIYFTSGTSG 226
Query: 335 KPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVL 394
PK H+ L + A D+ W +D GWI G L T
Sbjct: 227 LPKMAEHSYSSLGLKAKMDAGWT-GLQASDIMWTISDTGWILN----ILGSLLESWTLGA 281
Query: 395 FEGIPTYPDVNRLWSI--VDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVG 452
+ P + L + + Y + AP R+L++ + ++ + LQ G
Sbjct: 282 CTFVHLLPKFDPLVILKTLSSYPIKSMMGAPIVYRMLLQ---QDLSSYKFPHLQNCLAGG 338
Query: 453 EPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGAT-PMKPGSATFPFFGVAP 511
E + PE + G I + + QTETG LT + T +KPG + G A
Sbjct: 339 ESLLPETLENWRAQTGLD---IREFYGQTETG---LTCMVSKTMKIKPG-----YMGTAA 387
Query: 512 AILNES------GEELEGEAEGYLVFKQPWPGIMRTVY-GNHERFETTYFKKFPGYYVTG 564
+ + G G+ + G M + G+ E + T +++ G
Sbjct: 388 SCYDVQVIAFVHGSPRAGDLG--------FAGTMTLSFCGHQENPDKTAANIRGDFWLLG 439
Query: 565 DGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPVKGECL 624
D +D+DGY+ GR DD++N SG+ + +EVE+AL++H AV E AV+ P PV+GE +
Sbjct: 440 DRGIKDEDGYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVV 499
Query: 625 YCFVTLCDGH-TFSP-KLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRVLR 681
FV L + P +LT+EL++ ++ P P I+ LPKT +GKI R LR
Sbjct: 500 KAFVILASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKLR 558
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 103 bits (256), Expect = 7e-22
Identities = 102/385 (26%), Positives = 168/385 (43%), Gaps = 44/385 (11%)
Query: 326 ILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGP 385
I+YTSG+TG+PKGV+ T V T + + + +DV + + G P
Sbjct: 199 IIYTSGTTGRPKGVLSTHQNIRA-VVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCP 257
Query: 386 LANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTK------ 439
L GAT V+ + S + ++ F PT LM++ D T+
Sbjct: 258 LWVGATCVMMPEFSPQQVWEKFLSS-ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDF 316
Query: 440 -----HSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGA 494
+ L V G+ P+ P W + + G +++ + TE G + PL A
Sbjct: 317 LRAVCEEKIRLMVSGSAALPL-PVLEKWKN-ITGHT---LLERYGMTEIGMALSGPLTTA 371
Query: 495 TPMKPGSATFPFFGVAPAILNESGEE--------LEGEAEGYLV---FKQP-------WP 536
+ PGS P GV I++E+ + EG+ G V F++ P
Sbjct: 372 VRL-PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGP 430
Query: 537 GIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRID-DMLNVSGHLLSTA 595
+ R + E ++ + G++ TGD +DG YWI GR D++ G+ +S
Sbjct: 431 SVFREYWNKPEETKSAF--TLDGWFKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSAL 487
Query: 596 EVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPI 655
EVE L+ H ++ + AV+G P G+ + VTL +GH+ S + ELK+ R + P
Sbjct: 488 EVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHR---ELKEWARNVLAPY 544
Query: 656 ATPDYIQNAPGLPKTRSGKIMRRVL 680
A P + +P+ + GKI ++ L
Sbjct: 545 AVPSELVLVEEIPRNQMGKIDKKAL 569
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 103 bits (256), Expect = 7e-22
Identities = 102/385 (26%), Positives = 168/385 (43%), Gaps = 44/385 (11%)
Query: 326 ILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGP 385
I+YTSG+TG+PKGV+ T V T + + + +DV + + G P
Sbjct: 199 IIYTSGTTGRPKGVLSTHQNIRA-VVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCP 257
Query: 386 LANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTK------ 439
L GAT V+ + S + ++ F PT LM++ D T+
Sbjct: 258 LWVGATCVMMPEFSPQQVWEKFLSS-ETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDF 316
Query: 440 -----HSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGA 494
+ L V G+ P+ P W + + G +++ + TE G + PL A
Sbjct: 317 LRAVCEEKIRLMVSGSAALPL-PVLEKWKN-ITGHT---LLERYGMTEIGMALSGPLTTA 371
Query: 495 TPMKPGSATFPFFGVAPAILNESGEE--------LEGEAEGYLV---FKQP-------WP 536
+ PGS P GV I++E+ + EG+ G V F++ P
Sbjct: 372 VRL-PGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGP 430
Query: 537 GIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRID-DMLNVSGHLLSTA 595
+ R + E ++ + G++ TGD +DG YWI GR D++ G+ +S
Sbjct: 431 SVFREYWNKPEETKSAF--TLDGWFKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSAL 487
Query: 596 EVESALVEHEAVAEAAVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPI 655
EVE L+ H ++ + AV+G P G+ + VTL +GH+ S + ELK+ R + P
Sbjct: 488 EVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHR---ELKEWARNVLAPY 544
Query: 656 ATPDYIQNAPGLPKTRSGKIMRRVL 680
A P + +P+ + GKI ++ L
Sbjct: 545 AVPSELVLVEEIPRNQMGKIDKKAL 569
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 100 bits (250), Expect = 4e-21
Identities = 96/386 (24%), Positives = 159/386 (41%), Gaps = 67/386 (17%)
Query: 102 NICYNVLDRNVHEKKLGDKV---AFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GI 157
N +VLD+ ++K G K AF+W N GE + ++ +L +F+N+L + +
Sbjct: 59 NFAKDVLDQWTDKEKAGKKPSNPAFWWI-NRNGEEMRWSFEELGSLSRKFANILSEACSL 117
Query: 158 QKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAF 217
Q+GDRV + +P +PE +A +AC R G + + + + R+ S + +IT D
Sbjct: 118 QRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDV- 176
Query: 218 YRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277
L D KC+ + ++V R +
Sbjct: 177 --------LAPAVDAVASKCEN----LHSKLIVSENSR--------------------EG 204
Query: 278 QGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPK 337
G LKE LM+ A D + + I +TSG++G PK
Sbjct: 205 WGNLKE---------------------LMKHASDSHTCVKTKHNEIMAIFFTSGTSGYPK 243
Query: 338 GVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEG 397
HT + L ++ ++ D DV W T+D GW + P GA V
Sbjct: 244 MTAHTHSSFGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHH 302
Query: 398 IPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINP 457
+P + + L ++ KY +T F +APT R+L++ +T + SL+ + GEPI P
Sbjct: 303 LPRFEPTSILQTL-SKYPITVFCSAPTVYRMLVQ---NDITSYKFKSLKHCVSAGEPITP 358
Query: 458 EAWLWYHRVVGAQRCPIVDTFWQTET 483
+ + G I + + QTET
Sbjct: 359 DVTEKWRNKTGLD---IYEGYGQTET 381
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 76.3 bits (186), Expect = 9e-14
Identities = 112/500 (22%), Positives = 195/500 (39%), Gaps = 78/500 (15%)
Query: 102 NICYNVLDRNVHEKKLGDKVAF--YWEGNEPGETTQITYHQLLVQVCQFSNVLRKQ-GIQ 158
N +VLD+ +K G + + W+ + GE + ++ ++ + +++L +
Sbjct: 50 NFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEEDKWSFERMTQLSKKAASILSDTCALS 109
Query: 159 KGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSCSLLITTDAFY 218
GDR+ I +P PE LAC R+G F
Sbjct: 110 HGDRLMIILPPTPEAYWICLACVRLGI------------------------------TFV 139
Query: 219 RGEKLVNLKELADEA-LQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDV 277
G + K++ + + K Q CIV + S CP +
Sbjct: 140 PGSPQLTAKKIRYQLRMSKAQ--------CIVANEAMAPVVNSAVS---------DCPTL 182
Query: 278 QGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPK 337
+ KL K S++ +D + +L+Q A + ++DP+ I +T G+TG PK
Sbjct: 183 KTKLLVSDK------SYDGWLD--FKKLIQVAPPKQTYMRTKSQDPMAIFFTKGTTGAPK 234
Query: 338 GVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEG 397
V ++ G + + + D DV W D + G GA L
Sbjct: 235 MVEYSQYGLGMGFSQASRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCH- 293
Query: 398 IPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINP 457
+PT+ L +++ ++ +T P + L++ + T + SL+ G PI+P
Sbjct: 294 MPTFCPETVL-NVLSRFPITTLSANPEMYQELLQH--KCFTSYRFKSLKQCVAAGGPISP 350
Query: 458 EAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGSATFPFFGVAPAILNES 517
+ R+ + I + + QTETG +L +KP S P I++E+
Sbjct: 351 GVIEDWKRIT---KLDIYEGYGQTETG--LLCATSKTIKLKPSSLGKPLPPYIVQIVDEN 405
Query: 518 GEELEGEAEGYLVFK----QPWPGIMRTVYGNHE-RFETTYFKKFPGYYVTGDGCQRDQD 572
L EG + + QP ++Y H +E + Y+TGD D+D
Sbjct: 406 SNLLPPGEEGNIAIRIKLNQP-----ASLYCPHMVSWEEYASARGHMLYLTGDRGIMDED 460
Query: 573 GYYWITGRIDDMLNVSGHLL 592
GY+W +GR+DD+ N G L
Sbjct: 461 GYFWWSGRVDDVANALGQRL 480
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 67.0 bits (162), Expect = 6e-11
Identities = 126/570 (22%), Positives = 208/570 (36%), Gaps = 92/570 (16%)
Query: 137 TYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAMLACARIGALHSIVFAGFSS 196
T+ QL +N+ R+ G GD VAI++ PE V L A+ G +++
Sbjct: 105 TFAQLDAYSNAVANLFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRR 164
Query: 197 ESLCERILDSSCSLLITTDAFYRGEKLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRA 256
E L + S LI + GE + + E++ HLG++
Sbjct: 165 EPLAFCLGTSGAKALI-----FGGEMVAAVAEVSG--------------------HLGKS 199
Query: 257 ELGMGDSTSQSPPIKRSCPDVQGKLKEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPE 316
+ I + LKE S QI ++G+D
Sbjct: 200 LIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIP-SKGMD----------------- 241
Query: 317 WCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWIT 376
D LF +YTSG+TG PK + Y +A + + A DV + +
Sbjct: 242 -----DRLFYIYTSGTTGLPKAAIVVHSRYYR-MAAFGHHAYRMQAADVLYDCLPLYHSA 295
Query: 377 GHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEP 436
G+ L G T VL + +R W KY T R L+K +P
Sbjct: 296 GNIIGVGQCLIYGLTVVLRKKF----SASRFWDDCIKYNCTVVQYIGEICRYLLK---QP 348
Query: 437 VTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATP 496
V + R +V VG + P W + G ++ + F+ + + G
Sbjct: 349 VREAERRH-RVRLAVGNGLRPAIWEEFTERFGVRQ---IGEFYGATECNCSIANMDG--- 401
Query: 497 MKPGSATFP------FFGVAPAILNESGEELEGEAEGYLVFKQPW-PGIMRTVYGNHE-- 547
K GS F + + +NE EL +A+G + Q PG++ +
Sbjct: 402 -KVGSCGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPL 460
Query: 548 -RFET-------------TYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLS 593
RF+ + F K Y++GD D+ GY + R D G +S
Sbjct: 461 RRFDGYVSESATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVS 520
Query: 594 TAEVESALVEHEAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKI 652
T EVE L + AV G P V+G+ + D H+ + +++++ +
Sbjct: 521 TTEVEGVLSRLLGQTDVAVYGVAVPGVEGKA--GMAAVADPHSLLD--PNAIYQELQKVL 576
Query: 653 GPIATPDYIQNAPGLPKTRSGKIMRRVLRK 682
P A P +++ P + T + KI + L++
Sbjct: 577 APYARPIFLRLLPQVDTTGTFKIQKTRLQR 606
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 58.5 bits (140), Expect = 2e-08
Identities = 85/380 (22%), Positives = 141/380 (37%), Gaps = 34/380 (8%)
Query: 322 DPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYV 381
D LF +YTSG+TG PK + Y A + Y F D+ + + G+
Sbjct: 239 DKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVY-YGFRMRPNDIVYDCLPLYHSAGNIVG 297
Query: 382 TYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHS 441
L +G T V+ + +R W KY T R L+ ++P + +
Sbjct: 298 IGQCLLHGMTVVIRKKF----SASRFWDDCIKYNCTIVQYIGELCRYLL---NQP-PREA 349
Query: 442 RASLQVLGTVGEPINPEAWLWYH---------RVVGAQRCPIVDTFWQTETGG-----HM 487
QV +G + W + GA C + ++ G +
Sbjct: 350 ENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGACGFNSRI 409
Query: 488 LTPLPGATPMKPGSATFPFFGVAPAILNESGEELEGEAEGYLVFKQP---WPGIMRTVYG 544
L+ + ++ T + G+ G ++ K P + G +
Sbjct: 410 LSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDGYLNQG-A 468
Query: 545 NHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEH 604
N+++ FKK Y+TGD D+ GY + R D G +ST EVE L
Sbjct: 469 NNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRL 528
Query: 605 EAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPI-ATPDYIQ 662
+A+ AV G P +G V G+ + + L+K++ P+ A P +++
Sbjct: 529 LDMADVAVYGVEVPGTEGRAGMAAVASPTGNCDLERFAQVLEKEL-----PLYARPIFLR 583
Query: 663 NAPGLPKTRSGKIMRRVLRK 682
P L KT + K + LRK
Sbjct: 584 LLPELHKTGTYKFQKTELRK 603
Score = 37.0 bits (84), Expect = 0.064
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 119 DKVAFYWEGNEPGETTQITYHQLLVQVCQFSNVLRKQGIQKGDRVAIYMPMIPELVVAML 178
DK A +EG + T T+ QL +N L+ +G+ GD AI+M E V L
Sbjct: 89 DKTALIFEGTD----THWTFRQLDEYSSSVANFLQARGLASGDVAAIFMENRNEFVGLWL 144
Query: 179 ACARIGALHSIVFAGFSSESLCERILDSSCSLLI 212
A++G +++ ++L + S L+
Sbjct: 145 GMAKLGVEAALINTNLRRDALLHCLTTSRARALV 178
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 57.0 bits (136), Expect = 6e-08
Identities = 41/123 (33%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Query: 560 YYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVGHPHPV 619
+Y TGD ++ G+ I GR DM+ G + AE+E H V E VVG
Sbjct: 488 WYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVKDDR 547
Query: 620 KGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQNAPGLPKTRSGKIMRRV 679
GE + + L DG + EE+K + KI P YI P T SGKI +
Sbjct: 548 MGEEICACIRLKDGEETT---VEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFK 604
Query: 680 LRK 682
LR+
Sbjct: 605 LRE 607
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 56.6 bits (135), Expect = 8e-08
Identities = 86/380 (22%), Positives = 143/380 (37%), Gaps = 37/380 (9%)
Query: 323 PLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVT 382
P +YTSG+TG PK + T + + + A+DV + + + G
Sbjct: 289 PALFIYTSGTTGLPKPAILT--HERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLVVGI 346
Query: 383 YGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSR 442
G L GAT VL T + W ++ VT +R L +P +
Sbjct: 347 LGCLDLGATCVLAPKFST----SCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHT 402
Query: 443 ASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETG-------------GHMLT 489
L +G + + W + + G R I + + TE G M
Sbjct: 403 VRL----AMGNGLRADVWETFQQRFGPIR--IWEVYGSTEGNMGLVNYVGRCGALGKMSC 456
Query: 490 PLPGATPMKPGSATFPFFGVAPAILNES-----GEELEGEAEGYLVFKQPWPGIMRTVYG 544
L +P + F P N+ G G +V +QP+ G
Sbjct: 457 LLRMLSPFE--LVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPREL 514
Query: 545 NHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEH 604
+ + + YY TGD D++G+ + R+ D G +ST EVE L +
Sbjct: 515 SERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQV 574
Query: 605 EAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQN 663
+ + + V G P +G+ V L G TF E+L + +R + ATP +I+
Sbjct: 575 DFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFD---GEKLYQHVRAWLPAYATPHFIRI 631
Query: 664 APGLPKTRSGKIMR-RVLRK 682
+ T + K+M+ R++R+
Sbjct: 632 QDAMEVTSTFKLMKTRLVRE 651
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 51.2 bits (121), Expect = 3e-06
Identities = 85/404 (21%), Positives = 150/404 (37%), Gaps = 38/404 (9%)
Query: 322 DPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYV 381
D ++TSG+TG PK + + F + H EDV + + ++G
Sbjct: 328 DTCLYIFTSGTTGLPKAA--RISHLKILQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLG 385
Query: 382 TYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHS 441
G + GAT VL + W +++VT F R L+ ++P +K
Sbjct: 386 IVGCMGIGATVVLKSKF----SAGQFWEDCQQHRVTVFQYIGELCRYLV---NQPPSKAE 438
Query: 442 RASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHMLTPLPGATPMKPGS 501
R +V VG + P+ W + R G + +++T+ TE G++ T G
Sbjct: 439 RGH-KVRLAVGSGLRPDTWERFVRRFGPLQ--VLETYGLTE--GNVATINYTGQRGAVGR 493
Query: 502 ATFPFFGVAPAILNE----SGEELEGEAEGYLVFKQPW-PGIMRTVYGNHERF------- 549
A++ + + P L +GE + + +G+ + P PG++ F
Sbjct: 494 ASWLYKHIFPFSLIRYDVTTGEPIR-DPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGP 552
Query: 550 -------ETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALV 602
F+ ++ TGD D G+ R D G ++T EV
Sbjct: 553 ELAQGKLLKDVFRPGDVFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFE 612
Query: 603 EHEAVAEAAVVGHPHP-VKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYI 661
+ + E V G P +G + L H +L + E + P A P ++
Sbjct: 613 ALDFLQEVNVYGVTVPGHEGRAGMAALVLRPPHALD---LMQLYTHVSENLPPYARPRFL 669
Query: 662 QNAPGLPKTRSGKIMRRVLRKIAQNDHDLGDMSTVADPSVISHL 705
+ L T + K + + + L D V D +V ++L
Sbjct: 670 RLQESLATTETFKQQKVRMANEGFDPSTLSDPLYVLDQAVGAYL 713
>gi|45580730 aminoadipate-semialdehyde dehydrogenase [Homo sapiens]
Length = 1098
Score = 47.0 bits (110), Expect = 6e-05
Identities = 89/376 (23%), Positives = 153/376 (40%), Gaps = 44/376 (11%)
Query: 325 FILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYG 384
++L+TSG+TG PK +V ++ F+ +FD EDV + + + + + +
Sbjct: 194 YVLHTSGTTGIPK-IVRVPHKCIVPNIQHFRVLFDITQEDVLFLASPLTFDPSVVEI-FL 251
Query: 385 PLANGATSVLFEGIPTYPDV--NRLWSIV-DKYKVTKFYTAPTAIRLLMKFGDEPVTK-- 439
L++GA+ ++ +PT + ++L S++ ++VT PT LL +FG + +
Sbjct: 252 ALSSGASLLI---VPTSVKLLPSKLASVLFSHHRVTVLQATPT---LLRRFGSQLIKSTV 305
Query: 440 -HSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETGGHM-LTPLPGATPM 497
+ SL+VL GE L R G + I + + TE + +P T
Sbjct: 306 LSATTSLRVLALGGEAFPSLTVLRSWRGEG-NKTQIFNVYGITEVSSWATIYRIPEKTLN 364
Query: 498 K------PGSATFPFFGVAPAILNESGEEL-EGEAEGYLVFKQPWPGIMRTVYGNHERFE 550
P FP G + + +G + EG + +L G R + + E
Sbjct: 365 STLKCELPVQLGFPLLGTVVEVRDTNGFTIQEGSGQVFL------GGRNRVCFLDDEVTV 418
Query: 551 TTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEA 610
+ G +VT +DG + GR D + G L+ V+ E + V
Sbjct: 419 PLGTMRATGDFVTV------KDGEIFFLGRKDSQIKRHGKRLNIELVQQVAEELQQVESC 472
Query: 611 AVVGHPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQNAPGLPKT 670
AV + E L F+ D + E + K++++ + A PD + LP T
Sbjct: 473 AVTWYNQ----EKLILFMVSKDA-----SVKEYIFKELQKYLPSHAVPDELVLIDSLPFT 523
Query: 671 RSGKIMRRVLRKIAQN 686
GKI L KI N
Sbjct: 524 SHGKIDVSELNKIYLN 539
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 45.1 bits (105), Expect = 2e-04
Identities = 84/419 (20%), Positives = 154/419 (36%), Gaps = 39/419 (9%)
Query: 267 SPPIKRSCPDVQGKLKEKSKRVQ--PQISWNQGIDLWWHELMQEAGDECEPEWCDA---E 321
SP ++ + ++ LK+ + + S GID + ++ + + + W
Sbjct: 158 SPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFS 217
Query: 322 DPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYV 381
P +YTSG+TG PK + T ++ T +V A+DV + T
Sbjct: 218 TPALYIYTSGTTGLPKAAMIT--HQRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIG 275
Query: 382 TYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHS 441
+G + GAT L T ++ W KY VT +R L +P +
Sbjct: 276 IHGCIVAGATLAL----RTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDH 331
Query: 442 RASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETG------GHMLTPLPGAT 495
+ L +G + + W + + G C I + + TE + +
Sbjct: 332 KVRL----ALGNGLRGDVWRQFVKRFG-DIC-IYEFYAATEGNIGFMNYARKVGAVGRVN 385
Query: 496 PMKPGSATFPFFGV----APAILNESG---EELEGEAEGYLVFK----QPWPGIMRTVYG 544
++ T+ + +E+G +GE G LV K P+ G
Sbjct: 386 YLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEV-GLLVCKITQLTPFNGYAGAKAQ 444
Query: 545 NHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEH 604
++ FKK Y+ +GD D + + + R+ D G ++T EV +
Sbjct: 445 TEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLV 504
Query: 605 EAVAEAAVVG-HPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQ 662
+ V E V G H +G + + + H F K +L + I + + A P +++
Sbjct: 505 DFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGK---KLFQHIADYLPSYARPRFLR 560
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 45.1 bits (105), Expect = 2e-04
Identities = 111/530 (20%), Positives = 184/530 (34%), Gaps = 94/530 (17%)
Query: 107 VLDRNV-HEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNV-LRKQGIQKGDRVA 164
VLD+ + H K+ K +EG+ TY + + + ++V L ++KGD VA
Sbjct: 56 VLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVA 109
Query: 165 IYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSC---SLLITTDAFYRGE 221
+ M P+ V A++G + + + S SL I +C +L++ D E
Sbjct: 110 LLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCI--RACGPRALVVGADLLGTVE 167
Query: 222 KLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKL 281
++ L L++ + P + + L STS P+ RS
Sbjct: 168 EI--LPSLSENISVWGMKDSVPQGVISLKEKL---------STSPDEPVPRS-------- 208
Query: 282 KEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVH 341
H ++ C ++TSG+TG PK V
Sbjct: 209 ---------------------HHVVSLLKSTC-----------LYIFTSGTTGLPKAAV- 235
Query: 342 TVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTY 401
+ + + + F A D+ + T + + G + GAT VL +
Sbjct: 236 -ISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKF--- 291
Query: 402 PDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWL 461
++ WS KY VT F R L K K + L +G I + W
Sbjct: 292 -SASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRL----AIGNGIRSDVWR 346
Query: 462 WYHRVVGAQRCPIVDTFWQTETGGHMLT------PLPGATPMKPGSATFPF----FGVAP 511
+ G + + + TE+ + + +TF F
Sbjct: 347 EFLDRFG--NIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDE 404
Query: 512 AILNESG---EELEGEAEGYLV----FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTG 564
+ NE G +GE G L+ K P+ G ++ FKK Y TG
Sbjct: 405 PMRNEQGWCIHVKKGE-PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTG 463
Query: 565 DGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVG 614
D +DQD + + R D G ++T EV + + + EA V G
Sbjct: 464 DLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYG 513
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 45.1 bits (105), Expect = 2e-04
Identities = 111/530 (20%), Positives = 184/530 (34%), Gaps = 94/530 (17%)
Query: 107 VLDRNV-HEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNV-LRKQGIQKGDRVA 164
VLD+ + H K+ K +EG+ TY + + + ++V L ++KGD VA
Sbjct: 56 VLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVA 109
Query: 165 IYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSC---SLLITTDAFYRGE 221
+ M P+ V A++G + + + S SL I +C +L++ D E
Sbjct: 110 LLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCI--RACGPRALVVGADLLGTVE 167
Query: 222 KLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKL 281
++ L L++ + P + + L STS P+ RS
Sbjct: 168 EI--LPSLSENISVWGMKDSVPQGVISLKEKL---------STSPDEPVPRS-------- 208
Query: 282 KEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVH 341
H ++ C ++TSG+TG PK V
Sbjct: 209 ---------------------HHVVSLLKSTC-----------LYIFTSGTTGLPKAAV- 235
Query: 342 TVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTY 401
+ + + + F A D+ + T + + G + GAT VL +
Sbjct: 236 -ISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKF--- 291
Query: 402 PDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWL 461
++ WS KY VT F R L K K + L +G I + W
Sbjct: 292 -SASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRL----AIGNGIRSDVWR 346
Query: 462 WYHRVVGAQRCPIVDTFWQTETGGHMLT------PLPGATPMKPGSATFPF----FGVAP 511
+ G + + + TE+ + + +TF F
Sbjct: 347 EFLDRFG--NIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDE 404
Query: 512 AILNESG---EELEGEAEGYLV----FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTG 564
+ NE G +GE G L+ K P+ G ++ FKK Y TG
Sbjct: 405 PMRNEQGWCIHVKKGE-PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTG 463
Query: 565 DGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVG 614
D +DQD + + R D G ++T EV + + + EA V G
Sbjct: 464 DLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYG 513
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 35.0 bits (79), Expect = 0.24
Identities = 19/39 (48%), Positives = 25/39 (64%)
Query: 10 SGSGSRGQEEAGAGGRARSWSPPPEVSRSAHVPSLQRYR 48
SGS S +E +G+GGR RS S P+ S+SA P +R R
Sbjct: 5 SGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSR 43
>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
[Homo sapiens]
Length = 670
Score = 33.9 bits (76), Expect = 0.54
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 20/126 (15%)
Query: 233 ALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEK-------- 284
A Q C + FP+ + LG+ + G + S++ + S ++ KLK
Sbjct: 125 AAQTCFKYNFPL--VTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVK 182
Query: 285 -----SKRVQPQISWNQGIDLWWHELMQEAGDECE-----PEWCDAEDPLFILYTSGSTG 334
+ + + +G ++ + ++E G E P D ++YTSGSTG
Sbjct: 183 HIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTG 242
Query: 335 KPKGVV 340
+PKGV+
Sbjct: 243 RPKGVM 248
>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
2 [Homo sapiens]
Length = 711
Score = 33.9 bits (76), Expect = 0.54
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 20/126 (15%)
Query: 233 ALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKLKEK-------- 284
A Q C + FP+ + LG+ + G + S++ + S ++ KLK
Sbjct: 166 AAQTCFKYNFPL--VTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVK 223
Query: 285 -----SKRVQPQISWNQGIDLWWHELMQEAGDECE-----PEWCDAEDPLFILYTSGSTG 334
+ + + +G ++ + ++E G E P D ++YTSGSTG
Sbjct: 224 HIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTG 283
Query: 335 KPKGVV 340
+PKGV+
Sbjct: 284 RPKGVM 289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,852,432
Number of Sequences: 37866
Number of extensions: 1502941
Number of successful extensions: 3971
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 3849
Number of HSP's gapped (non-prelim): 74
length of query: 714
length of database: 18,247,518
effective HSP length: 109
effective length of query: 605
effective length of database: 14,120,124
effective search space: 8542675020
effective search space used: 8542675020
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.