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Search of human proteins with 121114287
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo
sapiens]
(1090 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] 2204 0.0
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 951 0.0
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 805 0.0
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 296 5e-80
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 296 5e-80
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 86 1e-16
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 86 1e-16
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 86 1e-16
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 86 1e-16
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 84 9e-16
gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni... 84 9e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 83 1e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 82 2e-15
gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 1... 82 3e-15
gi|163965366 nascent polypeptide-associated complex alpha subuni... 82 3e-15
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 77 9e-14
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 77 9e-14
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 77 1e-13
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 77 1e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 72 3e-12
gi|150378539 piccolo isoform 1 [Homo sapiens] 72 3e-12
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 71 6e-12
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 69 2e-11
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 69 2e-11
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 69 2e-11
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 69 3e-11
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 68 5e-11
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 67 9e-11
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ... 67 9e-11
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 67 1e-10
>gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]
Length = 1090
Score = 2204 bits (5710), Expect = 0.0
Identities = 1090/1090 (100%), Positives = 1090/1090 (100%)
Query: 1 MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDH 60
MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDH
Sbjct: 1 MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDH 60
Query: 61 MMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGVG 120
MMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGVG
Sbjct: 61 MMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGVG 120
Query: 121 NPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLK 180
NPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLK
Sbjct: 121 NPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLK 180
Query: 181 ERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQ 240
ERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQ
Sbjct: 181 ERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQ 240
Query: 241 QLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRN 300
QLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRN
Sbjct: 241 QLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRN 300
Query: 301 MEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPV 360
MEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPV
Sbjct: 301 MEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPV 360
Query: 361 LGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVK 420
LGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVK
Sbjct: 361 LGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVK 420
Query: 421 QGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLE 480
QGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLE
Sbjct: 421 QGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLE 480
Query: 481 RRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPA 540
RRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPA
Sbjct: 481 RRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPA 540
Query: 541 GDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSA 600
GDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSA
Sbjct: 541 GDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSA 600
Query: 601 LNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADG 660
LNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADG
Sbjct: 601 LNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADG 660
Query: 661 STVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGP 720
STVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGP
Sbjct: 661 STVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGP 720
Query: 721 NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP 780
NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP
Sbjct: 721 NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP 780
Query: 781 LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA 840
LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA
Sbjct: 781 LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA 840
Query: 841 PSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGE 900
PSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGE
Sbjct: 841 PSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGE 900
Query: 901 FDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHC 960
FDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHC
Sbjct: 901 FDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHC 960
Query: 961 AASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMN 1020
AASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMN
Sbjct: 961 AASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMN 1020
Query: 1021 KGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYP 1080
KGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYP
Sbjct: 1021 KGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYP 1080
Query: 1081 RIKPRQRTLA 1090
RIKPRQRTLA
Sbjct: 1081 RIKPRQRTLA 1090
>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
sapiens]
Length = 1134
Score = 951 bits (2458), Expect = 0.0
Identities = 551/1154 (47%), Positives = 703/1154 (60%), Gaps = 90/1154 (7%)
Query: 1 MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGSCHLAEVWRGNERPIPFDH 60
MMPM LTV+LSNNEQ TEVP+TPET CRDVV+ CKEPGE CHLAEVW G+ERP+ +
Sbjct: 7 MMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSERPVADNE 66
Query: 61 MMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGE-KRTENGV 119
M++ LQ++G +R EV+FFLRHE P + G R +Q+ +RN + VPGE +R ENGV
Sbjct: 67 RMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPR-SQDPSLKRNGVKVPGEYRRKENGV 125
Query: 120 GNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKL 179
+PR++LTL+ELQ+MA+RQQQQIE QQQ+L KEQRL FLKQQ++RQQQ ++E EKL++L
Sbjct: 126 NSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRL 185
Query: 180 KERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLS 239
KE E QE KLKK+RA++G V+ ++ NG L EIE+ + +FQ+K++E+ A+ +V++L+
Sbjct: 186 KEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELT 245
Query: 240 QQLEDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKR 299
+QLE LK G+++ A EL RLY+ELQ+RN+LNQEQN+KLQQQ+E LNKR
Sbjct: 246 RQLEMLKNGRIDSHHDNQS-----AVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKR 300
Query: 300 NMEVAMMDKRISELRERLYGKKIQLNRVNGT------SSPQSPLSTSGRVAAVGPYIQVP 353
N EVA+MDKR++ELR+RL+ KK L + + PQ S RVAAVGPYIQ
Sbjct: 301 NSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSS 360
Query: 354 SAGSFP----VLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAG 407
+ P +L P P S+ A+ G K P ++ ++S K + G
Sbjct: 361 TMPRMPSRPELLVKPALPDG-SLVIQASEGPMKIQ---TLPNMRSGAASQTKGSKIHPVG 416
Query: 408 ADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG-------KQLPP 460
DW + + QG+ S +AL + + + + + PP
Sbjct: 417 PDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPP 476
Query: 461 SYGTY-PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQP------- 512
S+GT + + + + + +P P +P++ + LP G T QP
Sbjct: 477 SFGTLRKNQSSEDILRDAQVANKNVAKVPPP---VPTKPKQINLPYFGQTNQPPSDIKPD 533
Query: 513 GSSQQIQ--------------QRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLA 558
GSSQQ+ Q+ V SP+ P G + SK E P A+RPF
Sbjct: 534 GSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTP 593
Query: 559 DKGSRP-QSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKS------VKAVYGK 611
P + PQTV +SSIYSMY QQ P KN+Q A SAL K+ +VYGK
Sbjct: 594 QPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGK 653
Query: 612 PVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLS 671
PV+ + H Q +P S EPE + ++ + E +PRPLS
Sbjct: 654 PVIAAAQNQQQ-----HPENIYSNSQGKPGS----PEPETEPVSSVQENHENERIPRPLS 704
Query: 672 PTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFN 731
PTKL P + +P R QSDADLEALR+KL+NAPRPLKKRSSITEPEGP GPNIQKLLYQR
Sbjct: 705 PTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTT 764
Query: 732 TLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDA 791
A P Y + + + V+ N + E+ + L E ++
Sbjct: 765 IAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNAST 824
Query: 792 NDNELPSPEP----EELICPQTTHQTAEPAEDNNNNVATV--------PTTEQIPSPVAE 839
++++P+P P E P + E+ N V P P P E
Sbjct: 825 ENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGE 884
Query: 840 APSPGEEQV---PPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDAS 896
PGE+ V PP S PP KRTNL+K SER HG+RV+FNPLALLLD+S
Sbjct: 885 PEGPGEDSVSMRPPEITGQVSLPP----GKRTNLRKTGSERIAHGMRVKFNPLALLLDSS 940
Query: 897 LEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWT 956
LEGEFDLVQRIIYEV+DPS PNDEGIT LHNAVCAGH IVKFL+ FGVNVNAADSDGWT
Sbjct: 941 LEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWT 1000
Query: 957 PLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKL 1016
PLHCAASCN+V +CK LVESGAA+FA T SD++TAADKCEEMEEGY QCSQFLYGVQEK+
Sbjct: 1001 PLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKM 1060
Query: 1017 GVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLL 1076
G+MNKGV YALWDYE QN DEL EGD +TI+ R+DE E EWWWARL D+EGYVP+NLL
Sbjct: 1061 GIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLL 1120
Query: 1077 GLYPRIKPRQRTLA 1090
GLYPRIKPRQR+LA
Sbjct: 1121 GLYPRIKPRQRSLA 1134
>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
sapiens]
Length = 1005
Score = 805 bits (2078), Expect = 0.0
Identities = 478/1030 (46%), Positives = 611/1030 (59%), Gaps = 88/1030 (8%)
Query: 124 VELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERV 183
++LTL+ELQ+MA+RQQQQIE QQQ+L KEQRL FLKQQ++RQQQ ++E EKL++LKE
Sbjct: 1 MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA 60
Query: 184 EAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLE 243
E QE KLKK+RA++G V+ ++ NG L EIE+ + +FQ+K++E+ A+ +V++L++QLE
Sbjct: 61 ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE 120
Query: 244 DLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEV 303
LK G+++ A EL RLY+ELQ+RN+LNQEQN+KLQQQ+E LNKRN EV
Sbjct: 121 MLKNGRIDSHHDNQS-----AVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEV 175
Query: 304 AMMDKRISELRERLYGKKIQLNRVNGT------SSPQSPLSTSGRVAAVGPYIQVPSAGS 357
A+MDKR++ELR+RL+ KK L + + PQ S RVAAVGPYIQ +
Sbjct: 176 AVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPR 235
Query: 358 FP----VLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAGADWK 411
P +L P P S+ A+ G K P ++ ++S K + G DW
Sbjct: 236 MPSRPELLVKPALPDG-SLVIQASEGPMKIQ---TLPNMRSGAASQTKGSKIHPVGPDWS 291
Query: 412 DPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG-------KQLPPSYGT 464
+ + QG+ S +AL + + + + + PPS+GT
Sbjct: 292 PSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGT 351
Query: 465 Y-PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQP-------GSSQ 516
+ + + + + +P P +P++ + LP G T QP GSSQ
Sbjct: 352 LRKNQSSEDILRDAQVANKNVAKVPPP---VPTKPKQINLPYFGQTNQPPSDIKPDGSSQ 408
Query: 517 QIQ--------------QRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562
Q+ Q+ V SP+ P G + SK E P A+RPF
Sbjct: 409 QLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSK 468
Query: 563 RP-QSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKS------VKAVYGKPVLP 615
P + PQTV +SSIYSMY QQ P KN+Q A SAL K+ +VYGKPV+
Sbjct: 469 DTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIA 528
Query: 616 SGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKL 675
+ H Q +P S EPE + ++ + E +PRPLSPTKL
Sbjct: 529 AAQNQQQ-----HPENIYSNSQGKPGS----PEPETEPVSSVQENHENERIPRPLSPTKL 579
Query: 676 TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAG 735
P + +P R QSDADLEALR+KL+NAPRPLKKRSSITEPEGP GPNIQKLLYQR A
Sbjct: 580 LPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAM 639
Query: 736 GMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNE 795
P Y + + + V+ N + E+ + L E ++ +++
Sbjct: 640 ETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSD 699
Query: 796 LPSPEP----EELICPQTTHQTAEPAEDNNNNVATV--------PTTEQIPSPVAEAPSP 843
+P+P P E P + E+ N V P P P E P
Sbjct: 700 MPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGP 759
Query: 844 GEEQV---PPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGE 900
GE+ V PP S PP KRTNL+K SER HG+RV+FNPLALLLD+SLEGE
Sbjct: 760 GEDSVSMRPPEITGQVSLPP----GKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGE 815
Query: 901 FDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHC 960
FDLVQRIIYEV+DPS PNDEGIT LHNAVCAGH IVKFL+ FGVNVNAADSDGWTPLHC
Sbjct: 816 FDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 875
Query: 961 AASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMN 1020
AASCN+V +CK LVESGAA+FA T SD++TAADKCEEMEEGY QCSQFLYGVQEK+G+MN
Sbjct: 876 AASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMN 935
Query: 1021 KGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYP 1080
KGV YALWDYE QN DEL EGD +TI+ R+DE E EWWWARL D+EGYVP+NLLGLYP
Sbjct: 936 KGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYP 995
Query: 1081 RIKPRQRTLA 1090
RIKPRQR+LA
Sbjct: 996 RIKPRQRSLA 1005
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 296 bits (759), Expect = 5e-80
Identities = 261/855 (30%), Positives = 374/855 (43%), Gaps = 118/855 (13%)
Query: 296 LNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSA 355
++ + ME+ ++ EL ++L + SP P +G + Y
Sbjct: 25 MDLKQMELDTAAAKVDELTKQLESL--------WSDSPAPPGPQAGPPSRPPRYSSSSIP 76
Query: 356 GSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAGADWKDP 413
F G P K + + ++ GRS+SA PTL S S K P + P
Sbjct: 77 EPFGSRGSPRK--AATDGADTPFGRSESA-----PTLHPYSPLSPKGRPSSPRTPLYLQP 129
Query: 414 SVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG---KQLPPSYGTY----- 465
GS+ + T S +P F G + +G+ P P PG G +Q PP+ +
Sbjct: 130 DAYGSLDRAT-SPRPRAFDGAGSS------LGRAPSPRPGPGPLRQQGPPTPFDFLGRAG 182
Query: 466 -PSPTPLGPGSTSSLERRKEGSLPRPSAGL----PSRQRPTLLPATGSTPQPGSSQQIQQ 520
P +PL G + R G PRP A S +LL + GS P Q
Sbjct: 183 SPRGSPLAEGPQAFFPER--GPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL 240
Query: 521 RISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIY 580
+ P + + A + KP + D +RP SP SS+
Sbjct: 241 TLRRRPPKAWNESDLDV--AYEKKPSQTASYE----RLDVFARPASPSLQLLPWRESSLD 294
Query: 581 SM------YLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTG 634
+ L AT P+NY+ + ++ +S Y + + GS PS L S
Sbjct: 295 GLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSL---GSAGPSGT--LPRSWQPV 349
Query: 635 TPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPL--SPTKLTPIVHSPLRYQSDADLE 692
+ P PPS +P P S + L + SPL ++
Sbjct: 350 SRIPMPPSSP---QPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPP-- 404
Query: 693 ALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLL--------YQRFNTLAGGMEGTPFYQ 744
KL P+P + S +P+ P P Q Q + + G P +
Sbjct: 405 ----KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPT-E 459
Query: 745 PSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEEL 804
P + G L V G+++E P A+P +P +PA +A +P E
Sbjct: 460 LEPEPEIEGLLTPVLEA-----GDVDEGPVARPLSPTRLQPALPPEAQS--VPELEEVAR 512
Query: 805 ICPQTTHQTAEPAEDNNNNVATVPTT-----EQIPSPVAE---APSPGEEQV-------- 848
+ + +P T +QI S + P PG +
Sbjct: 513 VLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEG 572
Query: 849 ------PPAPLPPASHPPAT-----------STNKRTNLKKPNSERTGHGLRVRFNPLAL 891
PPAP PPA PP S R+ L+K S R R R NPL L
Sbjct: 573 SEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKAR--RARLNPLVL 630
Query: 892 LLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAAD 951
LLDA+L GE ++VQ+ + E+ DPS+PN+EGIT LHNA+C ++ IV FL+ G NVN+ D
Sbjct: 631 LLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPD 690
Query: 952 SDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYG 1011
S GWTPLHCAASCN +C LV+ GAAIFA+T+SD TA +KC+ EGY C+ +L
Sbjct: 691 SHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYREGYADCATYLAD 750
Query: 1012 VQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYV 1071
V++ +G+MN G YALWDY A+ DELSF EG+++T+LRR ET+WWWA L +EGYV
Sbjct: 751 VEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYV 810
Query: 1072 PKNLLGLYPRIKPRQ 1086
P+N GL+PR+KP++
Sbjct: 811 PRNYFGLFPRVKPQR 825
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 296 bits (759), Expect = 5e-80
Identities = 261/855 (30%), Positives = 374/855 (43%), Gaps = 118/855 (13%)
Query: 296 LNKRNMEVAMMDKRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSA 355
++ + ME+ ++ EL ++L + SP P +G + Y
Sbjct: 25 MDLKQMELDTAAAKVDELTKQLESL--------WSDSPAPPGPQAGPPSRPPRYSSSSIP 76
Query: 356 GSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAGADWKDP 413
F G P K + + ++ GRS+SA PTL S S K P + P
Sbjct: 77 EPFGSRGSPRK--AATDGADTPFGRSESA-----PTLHPYSPLSPKGRPSSPRTPLYLQP 129
Query: 414 SVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG---KQLPPSYGTY----- 465
GS+ + T S +P F G + +G+ P P PG G +Q PP+ +
Sbjct: 130 DAYGSLDRAT-SPRPRAFDGAGSS------LGRAPSPRPGPGPLRQQGPPTPFDFLGRAG 182
Query: 466 -PSPTPLGPGSTSSLERRKEGSLPRPSAGL----PSRQRPTLLPATGSTPQPGSSQQIQQ 520
P +PL G + R G PRP A S +LL + GS P Q
Sbjct: 183 SPRGSPLAEGPQAFFPER--GPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL 240
Query: 521 RISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIY 580
+ P + + A + KP + D +RP SP SS+
Sbjct: 241 TLRRRPPKAWNESDLDV--AYEKKPSQTASYE----RLDVFARPASPSLQLLPWRESSLD 294
Query: 581 SM------YLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTG 634
+ L AT P+NY+ + ++ +S Y + + GS PS L S
Sbjct: 295 GLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSL---GSAGPSGT--LPRSWQPV 349
Query: 635 TPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPL--SPTKLTPIVHSPLRYQSDADLE 692
+ P PPS +P P S + L + SPL ++
Sbjct: 350 SRIPMPPSSP---QPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPP-- 404
Query: 693 ALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLL--------YQRFNTLAGGMEGTPFYQ 744
KL P+P + S +P+ P P Q Q + + G P +
Sbjct: 405 ----KLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPT-E 459
Query: 745 PSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEEL 804
P + G L V G+++E P A+P +P +PA +A +P E
Sbjct: 460 LEPEPEIEGLLTPVLEA-----GDVDEGPVARPLSPTRLQPALPPEAQS--VPELEEVAR 512
Query: 805 ICPQTTHQTAEPAEDNNNNVATVPTT-----EQIPSPVAE---APSPGEEQV-------- 848
+ + +P T +QI S + P PG +
Sbjct: 513 VLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEG 572
Query: 849 ------PPAPLPPASHPPAT-----------STNKRTNLKKPNSERTGHGLRVRFNPLAL 891
PPAP PPA PP S R+ L+K S R R R NPL L
Sbjct: 573 SEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKAR--RARLNPLVL 630
Query: 892 LLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAAD 951
LLDA+L GE ++VQ+ + E+ DPS+PN+EGIT LHNA+C ++ IV FL+ G NVN+ D
Sbjct: 631 LLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPD 690
Query: 952 SDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYG 1011
S GWTPLHCAASCN +C LV+ GAAIFA+T+SD TA +KC+ EGY C+ +L
Sbjct: 691 SHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYREGYADCATYLAD 750
Query: 1012 VQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYV 1071
V++ +G+MN G YALWDY A+ DELSF EG+++T+LRR ET+WWWA L +EGYV
Sbjct: 751 VEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYV 810
Query: 1072 PKNLLGLYPRIKPRQ 1086
P+N GL+PR+KP++
Sbjct: 811 PRNYFGLFPRVKPQR 825
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 86.3 bits (212), Expect = 1e-16
Identities = 126/564 (22%), Positives = 193/564 (34%), Gaps = 51/564 (9%)
Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390
++P+ P T+ + A P P+ P P +P + A + P
Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 391 T-LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449
+ P + A K+P+ + + +P P + P + P
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361
Query: 450 --PIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTL---- 502
P P K+ P+ PSPT P P T++ P P+ ++ PT
Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEP 418
Query: 503 LPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562
P T P P + ++ P+PT P P P K P T K
Sbjct: 419 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEP 474
Query: 563 RPQSPRK-GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSP 621
P +P++ P T + + T P+ P L + P P+ +T
Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT------PEEPTPTTPE 528
Query: 622 SPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGS---TVESLPRPLSPTKL--- 675
P P + + TP+ P+ +T KEP P PA + T + P+ +PT L
Sbjct: 529 EPAPTTPKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 586
Query: 676 ---TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT 732
TP +P E K ++ T P+ P P K + T
Sbjct: 587 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA-PTTPK---EPAPT 642
Query: 733 LAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP------LPAEPA 786
G T +P+P+ ++ T + PA PT P P EPA
Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-PTTPKETAPTTPKEPA 701
Query: 787 PSSDANDN----ELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPS 842
P++ E P P E+ P TT EP + + + P P+P A S
Sbjct: 702 PTTPKKPAPTTPETPPPTTSEVSTPTTTK---EPTTIHKSPDESTPELSAEPTPKALENS 758
Query: 843 PGEEQVPPAPLPPASHPPATSTNK 866
P E VP P A+ P T+T K
Sbjct: 759 PKEPGVPTTKTPAATKPEMTTTAK 782
Score = 60.1 bits (144), Expect = 1e-08
Identities = 96/453 (21%), Positives = 146/453 (32%), Gaps = 95/453 (20%)
Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507
PP + G L G + TP TS+ + K + P+ + P RP+L P +
Sbjct: 82 PPVVDEAGSGL--DNGDFKVTTP----DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 135
Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP-----------F 556
++ + +S + + +V T + + T +I
Sbjct: 136 TSKE--TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 193
Query: 557 LADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPS 616
LA + ++ KGP ++ TP +PA+ + + + P P
Sbjct: 194 LAKPTPKAETTTKGPALTTP--------KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245
Query: 617 GSTSPSPLPFLHGSLSTGTPQPQP-----PSESTEKEPEQDGPAAPADGSTVESLPRPLS 671
P P S T +P P P+ +T KEP PA +T + P
Sbjct: 246 -----EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300
Query: 672 PTKLTPIVHSPLRYQSDADLEALRRK--LANAPRPLKKRSSITEPEGPGGPNIQKLLYQR 729
P TP +P + A P P K + T P+ P P K
Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPK----- 354
Query: 730 FNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSS 789
+P+P+ P +P P EPAP++
Sbjct: 355 --------------KPAPTT------------------------PKEPAPTTPKEPAPTT 376
Query: 790 DANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVA---EAPSPGEE 846
+ EP T EPA + PTT + PSP AP+ +E
Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKE 433
Query: 847 QVPPAPLPPA---SHPPATSTNKR---TNLKKP 873
P P PA PA +T K T KKP
Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 466
Score = 60.1 bits (144), Expect = 1e-08
Identities = 105/512 (20%), Positives = 160/512 (31%), Gaps = 81/512 (15%)
Query: 423 TVSSQPVPFSALGP----TEKPGIEIGKVPPPI------PGVGKQLPPSYGTYPSPTPLG 472
T +P P + P T+KP K P P P K+L P+ +PT
Sbjct: 445 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 504
Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTL----LPATGSTPQPGSSQQIQQRISVPPSP 528
+ ++ E + P+ P PT P T P P + ++ P+P
Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564
Query: 529 TYPPAGPPAFPAGDSK----------PELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSS 578
T P P P G + P+ P + P + + + P T ++
Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 624
Query: 579 IYSMYLQQATPPKNYQPA-----AHSALNKSVKAVYGKPVL----------PSGSTSPSP 623
+ T PK P A + L + KP P+ +TS P
Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684
Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683
P T P+ P+ +T K+P P P T + P + + T I SP
Sbjct: 685 APTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPP--TTSEVSTPTTTKEPTTIHKSPD 740
Query: 684 RYQSDADLEALRRKLANAPR----PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG 739
+ E + L N+P+ P K + T+PE + T +
Sbjct: 741 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE--------MTTTAKDKTTERDLRT 792
Query: 740 TP---FYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEP------APSSD 790
TP P +++ T A Q T P AP
Sbjct: 793 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852
Query: 791 ANDNELPSPE----PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846
+ + E PEE TA+P + N+ AT P P +AP
Sbjct: 853 TTKKTITTTEIMNKPEE---------TAKPKDRATNSKATTPK----PQKPTKAPKKPTS 899
Query: 847 QVPPAPLPPASHPPATSTNKRTNLKKPNSERT 878
P +P P T T ++ P T
Sbjct: 900 TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 931
Score = 44.3 bits (103), Expect = 6e-04
Identities = 79/385 (20%), Positives = 133/385 (34%), Gaps = 53/385 (13%)
Query: 331 SSPQSPLSTSGR-VAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389
++P+ P T+ + A P P+ P P KP +A + + D
Sbjct: 557 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 616
Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSS---QPVPFSA-------LGPTEK 439
PT + ++ + P + A K+P+ + +GT + +P P + L PT
Sbjct: 617 PTTPKGTAPTT-PKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 673
Query: 440 PGIEIGKVPPPIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498
G P P K+ P+ P+PT P P T+ P P+ S
Sbjct: 674 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-------ETPPPTTSEVSTP 726
Query: 499 RPTLLPAT------GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVA 552
T P T STP+ + + + P P P PA +KPE+ T
Sbjct: 727 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAK 782
Query: 553 IRPFLADKGSRPQSPRKGPQ-----------------TVNSSSIYSMYLQQATPPKNYQP 595
+ D + P++ P+ T ++ + S Q TP K
Sbjct: 783 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 842
Query: 596 AAHSALNK---SVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQD 652
+ K + K + ++ + P S +T TP+PQ P+++ +K
Sbjct: 843 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT-TPKPQKPTKAPKKPTSTK 901
Query: 653 GPAAPADGSTVESLPRPLSPTKLTP 677
P ++ P P T P
Sbjct: 902 KPKTMPRVRKPKTTPTPRKMTSTMP 926
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 86.3 bits (212), Expect = 1e-16
Identities = 126/564 (22%), Positives = 193/564 (34%), Gaps = 51/564 (9%)
Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390
++P+ P T+ + A P P+ P P +P + A + P
Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 391 T-LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449
+ P + A K+P+ + + +P P + P + P
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402
Query: 450 --PIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTL---- 502
P P K+ P+ PSPT P P T++ P P+ ++ PT
Sbjct: 403 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEP 459
Query: 503 LPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562
P T P P + ++ P+PT P P P K P T K
Sbjct: 460 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEP 515
Query: 563 RPQSPRK-GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSP 621
P +P++ P T + + T P+ P L + P P+ +T
Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT------PEEPTPTTPE 569
Query: 622 SPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGS---TVESLPRPLSPTKL--- 675
P P + + TP+ P+ +T KEP P PA + T + P+ +PT L
Sbjct: 570 EPAPTTPKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 627
Query: 676 ---TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT 732
TP +P E K ++ T P+ P P K + T
Sbjct: 628 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA-PTTPK---EPAPT 683
Query: 733 LAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP------LPAEPA 786
G T +P+P+ ++ T + PA PT P P EPA
Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-PTTPKETAPTTPKEPA 742
Query: 787 PSSDANDN----ELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPS 842
P++ E P P E+ P TT EP + + + P P+P A S
Sbjct: 743 PTTPKKPAPTTPETPPPTTSEVSTPTTTK---EPTTIHKSPDESTPELSAEPTPKALENS 799
Query: 843 PGEEQVPPAPLPPASHPPATSTNK 866
P E VP P A+ P T+T K
Sbjct: 800 PKEPGVPTTKTPAATKPEMTTTAK 823
Score = 60.1 bits (144), Expect = 1e-08
Identities = 96/453 (21%), Positives = 146/453 (32%), Gaps = 95/453 (20%)
Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507
PP + G L G + TP TS+ + K + P+ + P RP+L P +
Sbjct: 123 PPVVDEAGSGL--DNGDFKVTTP----DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 176
Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP-----------F 556
++ + +S + + +V T + + T +I
Sbjct: 177 TSKE--TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 234
Query: 557 LADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPS 616
LA + ++ KGP ++ TP +PA+ + + + P P
Sbjct: 235 LAKPTPKAETTTKGPALTTP--------KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286
Query: 617 GSTSPSPLPFLHGSLSTGTPQPQP-----PSESTEKEPEQDGPAAPADGSTVESLPRPLS 671
P P S T +P P P+ +T KEP PA +T + P
Sbjct: 287 -----EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341
Query: 672 PTKLTPIVHSPLRYQSDADLEALRRK--LANAPRPLKKRSSITEPEGPGGPNIQKLLYQR 729
P TP +P + A P P K + T P+ P P K
Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPK----- 395
Query: 730 FNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSS 789
+P+P+ P +P P EPAP++
Sbjct: 396 --------------KPAPTT------------------------PKEPAPTTPKEPAPTT 417
Query: 790 DANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVA---EAPSPGEE 846
+ EP T EPA + PTT + PSP AP+ +E
Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKE 474
Query: 847 QVPPAPLPPA---SHPPATSTNKR---TNLKKP 873
P P PA PA +T K T KKP
Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 507
Score = 60.1 bits (144), Expect = 1e-08
Identities = 105/512 (20%), Positives = 160/512 (31%), Gaps = 81/512 (15%)
Query: 423 TVSSQPVPFSALGP----TEKPGIEIGKVPPPI------PGVGKQLPPSYGTYPSPTPLG 472
T +P P + P T+KP K P P P K+L P+ +PT
Sbjct: 486 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 545
Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTL----LPATGSTPQPGSSQQIQQRISVPPSP 528
+ ++ E + P+ P PT P T P P + ++ P+P
Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605
Query: 529 TYPPAGPPAFPAGDSK----------PELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSS 578
T P P P G + P+ P + P + + + P T ++
Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 665
Query: 579 IYSMYLQQATPPKNYQPA-----AHSALNKSVKAVYGKPVL----------PSGSTSPSP 623
+ T PK P A + L + KP P+ +TS P
Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725
Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683
P T P+ P+ +T K+P P P T + P + + T I SP
Sbjct: 726 APTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPP--TTSEVSTPTTTKEPTTIHKSPD 781
Query: 684 RYQSDADLEALRRKLANAPR----PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG 739
+ E + L N+P+ P K + T+PE + T +
Sbjct: 782 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE--------MTTTAKDKTTERDLRT 833
Query: 740 TP---FYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEP------APSSD 790
TP P +++ T A Q T P AP
Sbjct: 834 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893
Query: 791 ANDNELPSPE----PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846
+ + E PEE TA+P + N+ AT P P +AP
Sbjct: 894 TTKKTITTTEIMNKPEE---------TAKPKDRATNSKATTPK----PQKPTKAPKKPTS 940
Query: 847 QVPPAPLPPASHPPATSTNKRTNLKKPNSERT 878
P +P P T T ++ P T
Sbjct: 941 TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 972
Score = 44.3 bits (103), Expect = 6e-04
Identities = 79/385 (20%), Positives = 133/385 (34%), Gaps = 53/385 (13%)
Query: 331 SSPQSPLSTSGR-VAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389
++P+ P T+ + A P P+ P P KP +A + + D
Sbjct: 598 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 657
Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSS---QPVPFSA-------LGPTEK 439
PT + ++ + P + A K+P+ + +GT + +P P + L PT
Sbjct: 658 PTTPKGTAPTT-PKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 714
Query: 440 PGIEIGKVPPPIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498
G P P K+ P+ P+PT P P T+ P P+ S
Sbjct: 715 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-------ETPPPTTSEVSTP 767
Query: 499 RPTLLPAT------GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVA 552
T P T STP+ + + + P P P PA +KPE+ T
Sbjct: 768 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAK 823
Query: 553 IRPFLADKGSRPQSPRKGPQ-----------------TVNSSSIYSMYLQQATPPKNYQP 595
+ D + P++ P+ T ++ + S Q TP K
Sbjct: 824 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 883
Query: 596 AAHSALNK---SVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQD 652
+ K + K + ++ + P S +T TP+PQ P+++ +K
Sbjct: 884 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT-TPKPQKPTKAPKKPTSTK 942
Query: 653 GPAAPADGSTVESLPRPLSPTKLTP 677
P ++ P P T P
Sbjct: 943 KPKTMPRVRKPKTTPTPRKMTSTMP 967
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 86.3 bits (212), Expect = 1e-16
Identities = 126/564 (22%), Positives = 193/564 (34%), Gaps = 51/564 (9%)
Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390
++P+ P T+ + A P P+ P P +P + A + P
Sbjct: 335 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 394
Query: 391 T-LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449
+ P + A K+P+ + + +P P + P + P
Sbjct: 395 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454
Query: 450 --PIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTL---- 502
P P K+ P+ PSPT P P T++ P P+ ++ PT
Sbjct: 455 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEP 511
Query: 503 LPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562
P T P P + ++ P+PT P P P K P T K
Sbjct: 512 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEP 567
Query: 563 RPQSPRK-GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSP 621
P +P++ P T + + T P+ P L + P P+ +T
Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT------PEEPTPTTPE 621
Query: 622 SPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGS---TVESLPRPLSPTKL--- 675
P P + + TP+ P+ +T KEP P PA + T + P+ +PT L
Sbjct: 622 EPAPTTPKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679
Query: 676 ---TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT 732
TP +P E K ++ T P+ P P K + T
Sbjct: 680 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA-PTTPK---EPAPT 735
Query: 733 LAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP------LPAEPA 786
G T +P+P+ ++ T + PA PT P P EPA
Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-PTTPKETAPTTPKEPA 794
Query: 787 PSSDANDN----ELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPS 842
P++ E P P E+ P TT EP + + + P P+P A S
Sbjct: 795 PTTPKKPAPTTPETPPPTTSEVSTPTTTK---EPTTIHKSPDESTPELSAEPTPKALENS 851
Query: 843 PGEEQVPPAPLPPASHPPATSTNK 866
P E VP P A+ P T+T K
Sbjct: 852 PKEPGVPTTKTPAATKPEMTTTAK 875
Score = 60.1 bits (144), Expect = 1e-08
Identities = 96/453 (21%), Positives = 146/453 (32%), Gaps = 95/453 (20%)
Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507
PP + G L G + TP TS+ + K + P+ + P RP+L P +
Sbjct: 175 PPVVDEAGSGL--DNGDFKVTTP----DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 228
Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP-----------F 556
++ + +S + + +V T + + T +I
Sbjct: 229 TSKE--TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 286
Query: 557 LADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPS 616
LA + ++ KGP ++ TP +PA+ + + + P P
Sbjct: 287 LAKPTPKAETTTKGPALTTP--------KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338
Query: 617 GSTSPSPLPFLHGSLSTGTPQPQP-----PSESTEKEPEQDGPAAPADGSTVESLPRPLS 671
P P S T +P P P+ +T KEP PA +T + P
Sbjct: 339 -----EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393
Query: 672 PTKLTPIVHSPLRYQSDADLEALRRK--LANAPRPLKKRSSITEPEGPGGPNIQKLLYQR 729
P TP +P + A P P K + T P+ P P K
Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPK----- 447
Query: 730 FNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSS 789
+P+P+ P +P P EPAP++
Sbjct: 448 --------------KPAPTT------------------------PKEPAPTTPKEPAPTT 469
Query: 790 DANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVA---EAPSPGEE 846
+ EP T EPA + PTT + PSP AP+ +E
Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKE 526
Query: 847 QVPPAPLPPA---SHPPATSTNKR---TNLKKP 873
P P PA PA +T K T KKP
Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 559
Score = 60.1 bits (144), Expect = 1e-08
Identities = 105/512 (20%), Positives = 160/512 (31%), Gaps = 81/512 (15%)
Query: 423 TVSSQPVPFSALGP----TEKPGIEIGKVPPPI------PGVGKQLPPSYGTYPSPTPLG 472
T +P P + P T+KP K P P P K+L P+ +PT
Sbjct: 538 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 597
Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTL----LPATGSTPQPGSSQQIQQRISVPPSP 528
+ ++ E + P+ P PT P T P P + ++ P+P
Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657
Query: 529 TYPPAGPPAFPAGDSK----------PELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSS 578
T P P P G + P+ P + P + + + P T ++
Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 717
Query: 579 IYSMYLQQATPPKNYQPA-----AHSALNKSVKAVYGKPVL----------PSGSTSPSP 623
+ T PK P A + L + KP P+ +TS P
Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777
Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683
P T P+ P+ +T K+P P P T + P + + T I SP
Sbjct: 778 APTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPP--TTSEVSTPTTTKEPTTIHKSPD 833
Query: 684 RYQSDADLEALRRKLANAPR----PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG 739
+ E + L N+P+ P K + T+PE + T +
Sbjct: 834 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE--------MTTTAKDKTTERDLRT 885
Query: 740 TP---FYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEP------APSSD 790
TP P +++ T A Q T P AP
Sbjct: 886 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 945
Query: 791 ANDNELPSPE----PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846
+ + E PEE TA+P + N+ AT P P +AP
Sbjct: 946 TTKKTITTTEIMNKPEE---------TAKPKDRATNSKATTPK----PQKPTKAPKKPTS 992
Query: 847 QVPPAPLPPASHPPATSTNKRTNLKKPNSERT 878
P +P P T T ++ P T
Sbjct: 993 TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1024
Score = 44.3 bits (103), Expect = 6e-04
Identities = 79/385 (20%), Positives = 133/385 (34%), Gaps = 53/385 (13%)
Query: 331 SSPQSPLSTSGR-VAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389
++P+ P T+ + A P P+ P P KP +A + + D
Sbjct: 650 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 709
Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSS---QPVPFSA-------LGPTEK 439
PT + ++ + P + A K+P+ + +GT + +P P + L PT
Sbjct: 710 PTTPKGTAPTT-PKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 766
Query: 440 PGIEIGKVPPPIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498
G P P K+ P+ P+PT P P T+ P P+ S
Sbjct: 767 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-------ETPPPTTSEVSTP 819
Query: 499 RPTLLPAT------GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVA 552
T P T STP+ + + + P P P PA +KPE+ T
Sbjct: 820 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAK 875
Query: 553 IRPFLADKGSRPQSPRKGPQ-----------------TVNSSSIYSMYLQQATPPKNYQP 595
+ D + P++ P+ T ++ + S Q TP K
Sbjct: 876 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 935
Query: 596 AAHSALNK---SVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQD 652
+ K + K + ++ + P S +T TP+PQ P+++ +K
Sbjct: 936 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT-TPKPQKPTKAPKKPTSTK 994
Query: 653 GPAAPADGSTVESLPRPLSPTKLTP 677
P ++ P P T P
Sbjct: 995 KPKTMPRVRKPKTTPTPRKMTSTMP 1019
Score = 33.9 bits (76), Expect = 0.86
Identities = 53/271 (19%), Positives = 92/271 (33%), Gaps = 39/271 (14%)
Query: 615 PSGSTSPSPLPFLHGSLSTGTPQPQPPSE-STEKEPEQDGPAAPADGSTVESLPRPLSPT 673
PS +P P ST P+PP++ T+K E + S + S +
Sbjct: 73 PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 132
Query: 674 KLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTL 733
+ + ++ A L++KL + KK + +P P P + +
Sbjct: 133 SSSSTIRKIKSSKNSAANRELQKKL--KVKDNKKNRTKKKPT-PKPPVVDE--------A 181
Query: 734 AGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDAND 793
G++ + DF T D N ++ A+P P P+ P S + +
Sbjct: 182 GSGLD---------NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 232
Query: 794 NELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQI-----------------PSP 836
L + + +TT + + D + T+ I P+P
Sbjct: 233 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 292
Query: 837 VAEAPSPGEE-QVPPAPLPPASHPPATSTNK 866
AE + G P P P PA++T K
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPK 323
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 86.3 bits (212), Expect = 1e-16
Identities = 126/564 (22%), Positives = 193/564 (34%), Gaps = 51/564 (9%)
Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390
++P+ P T+ + A P P+ P P +P + A + P
Sbjct: 376 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP 435
Query: 391 T-LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449
+ P + A K+P+ + + +P P + P + P
Sbjct: 436 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 495
Query: 450 --PIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTL---- 502
P P K+ P+ PSPT P P T++ P P+ ++ PT
Sbjct: 496 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEP 552
Query: 503 LPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562
P T P P + ++ P+PT P P P K P T K
Sbjct: 553 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPAPTTTKKPAPTTPKEP 608
Query: 563 RPQSPRK-GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSP 621
P +P++ P T + + T P+ P L + P P+ +T
Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT------PEEPTPTTPE 662
Query: 622 SPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGS---TVESLPRPLSPTKL--- 675
P P + + TP+ P+ +T KEP P PA + T + P+ +PT L
Sbjct: 663 EPAPTTPKAAAPNTPKE--PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720
Query: 676 ---TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT 732
TP +P E K ++ T P+ P P K + T
Sbjct: 721 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA-PTTPK---EPAPT 776
Query: 733 LAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP------LPAEPA 786
G T +P+P+ ++ T + PA PT P P EPA
Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-PTTPKETAPTTPKEPA 835
Query: 787 PSSDANDN----ELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPS 842
P++ E P P E+ P TT EP + + + P P+P A S
Sbjct: 836 PTTPKKPAPTTPETPPPTTSEVSTPTTTK---EPTTIHKSPDESTPELSAEPTPKALENS 892
Query: 843 PGEEQVPPAPLPPASHPPATSTNK 866
P E VP P A+ P T+T K
Sbjct: 893 PKEPGVPTTKTPAATKPEMTTTAK 916
Score = 60.1 bits (144), Expect = 1e-08
Identities = 96/453 (21%), Positives = 146/453 (32%), Gaps = 95/453 (20%)
Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507
PP + G L G + TP TS+ + K + P+ + P RP+L P +
Sbjct: 216 PPVVDEAGSGL--DNGDFKVTTP----DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD 269
Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP-----------F 556
++ + +S + + +V T + + T +I
Sbjct: 270 TSKE--TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 327
Query: 557 LADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPS 616
LA + ++ KGP ++ TP +PA+ + + + P P
Sbjct: 328 LAKPTPKAETTTKGPALTTP--------KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379
Query: 617 GSTSPSPLPFLHGSLSTGTPQPQP-----PSESTEKEPEQDGPAAPADGSTVESLPRPLS 671
P P S T +P P P+ +T KEP PA +T + P
Sbjct: 380 -----EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434
Query: 672 PTKLTPIVHSPLRYQSDADLEALRRK--LANAPRPLKKRSSITEPEGPGGPNIQKLLYQR 729
P TP +P + A P P K + T P+ P P K
Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-PTAPK----- 488
Query: 730 FNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSS 789
+P+P+ P +P P EPAP++
Sbjct: 489 --------------KPAPTT------------------------PKEPAPTTPKEPAPTT 510
Query: 790 DANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVA---EAPSPGEE 846
+ EP T EPA + PTT + PSP AP+ +E
Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEPAP---TTTKSAPTTPKEPSPTTTKEPAPTTPKE 567
Query: 847 QVPPAPLPPA---SHPPATSTNKR---TNLKKP 873
P P PA PA +T K T KKP
Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 600
Score = 60.1 bits (144), Expect = 1e-08
Identities = 105/512 (20%), Positives = 160/512 (31%), Gaps = 81/512 (15%)
Query: 423 TVSSQPVPFSALGP----TEKPGIEIGKVPPPI------PGVGKQLPPSYGTYPSPTPLG 472
T +P P + P T+KP K P P P K+L P+ +PT
Sbjct: 579 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 638
Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTL----LPATGSTPQPGSSQQIQQRISVPPSP 528
+ ++ E + P+ P PT P T P P + ++ P+P
Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698
Query: 529 TYPPAGPPAFPAGDSK----------PELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSS 578
T P P P G + P+ P + P + + + P T ++
Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 758
Query: 579 IYSMYLQQATPPKNYQPA-----AHSALNKSVKAVYGKPVL----------PSGSTSPSP 623
+ T PK P A + L + KP P+ +TS P
Sbjct: 759 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818
Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683
P T P+ P+ +T K+P P P T + P + + T I SP
Sbjct: 819 APTT--PKETAPTTPKEPAPTTPKKPAPTTPETPPP--TTSEVSTPTTTKEPTTIHKSPD 874
Query: 684 RYQSDADLEALRRKLANAPR----PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEG 739
+ E + L N+P+ P K + T+PE + T +
Sbjct: 875 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE--------MTTTAKDKTTERDLRT 926
Query: 740 TP---FYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEP------APSSD 790
TP P +++ T A Q T P AP
Sbjct: 927 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 986
Query: 791 ANDNELPSPE----PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846
+ + E PEE TA+P + N+ AT P P +AP
Sbjct: 987 TTKKTITTTEIMNKPEE---------TAKPKDRATNSKATTPK----PQKPTKAPKKPTS 1033
Query: 847 QVPPAPLPPASHPPATSTNKRTNLKKPNSERT 878
P +P P T T ++ P T
Sbjct: 1034 TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1065
Score = 44.3 bits (103), Expect = 6e-04
Identities = 79/385 (20%), Positives = 133/385 (34%), Gaps = 53/385 (13%)
Query: 331 SSPQSPLSTSGR-VAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389
++P+ P T+ + A P P+ P P KP +A + + D
Sbjct: 691 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 750
Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSS---QPVPFSA-------LGPTEK 439
PT + ++ + P + A K+P+ + +GT + +P P + L PT
Sbjct: 751 PTTPKGTAPTT-PKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 807
Query: 440 PGIEIGKVPPPIPGVGKQLPPSYGTYPSPT-PLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498
G P P K+ P+ P+PT P P T+ P P+ S
Sbjct: 808 KGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTP-------ETPPPTTSEVSTP 860
Query: 499 RPTLLPAT------GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVA 552
T P T STP+ + + + P P P PA +KPE+ T
Sbjct: 861 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA----TKPEMTTTAK 916
Query: 553 IRPFLADKGSRPQSPRKGPQ-----------------TVNSSSIYSMYLQQATPPKNYQP 595
+ D + P++ P+ T ++ + S Q TP K
Sbjct: 917 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 976
Query: 596 AAHSALNK---SVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQD 652
+ K + K + ++ + P S +T TP+PQ P+++ +K
Sbjct: 977 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT-TPKPQKPTKAPKKPTSTK 1035
Query: 653 GPAAPADGSTVESLPRPLSPTKLTP 677
P ++ P P T P
Sbjct: 1036 KPKTMPRVRKPKTTPTPRKMTSTMP 1060
Score = 33.9 bits (76), Expect = 0.86
Identities = 53/271 (19%), Positives = 92/271 (33%), Gaps = 39/271 (14%)
Query: 615 PSGSTSPSPLPFLHGSLSTGTPQPQPPSE-STEKEPEQDGPAAPADGSTVESLPRPLSPT 673
PS +P P ST P+PP++ T+K E + S + S +
Sbjct: 114 PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 173
Query: 674 KLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTL 733
+ + ++ A L++KL + KK + +P P P + +
Sbjct: 174 SSSSTIRKIKSSKNSAANRELQKKL--KVKDNKKNRTKKKPT-PKPPVVDE--------A 222
Query: 734 AGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDAND 793
G++ + DF T D N ++ A+P P P+ P S + +
Sbjct: 223 GSGLD---------NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 273
Query: 794 NELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQI-----------------PSP 836
L + + +TT + + D + T+ I P+P
Sbjct: 274 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 333
Query: 837 VAEAPSPGEE-QVPPAPLPPASHPPATSTNK 866
AE + G P P P PA++T K
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPK 364
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 83.6 bits (205), Expect = 9e-16
Identities = 154/591 (26%), Positives = 208/591 (35%), Gaps = 76/591 (12%)
Query: 329 GTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIAS-------NAAHGRS 381
GT SP + VG PSA P P K S+S AS + A R
Sbjct: 161 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK--SVSSASEHSTTEPSPAARRR 218
Query: 382 KSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVP--FSALGPTEK 439
SA G ++ SSS P+ PS G+ + SQP P AL P +
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALRPPQ- 275
Query: 440 PGIEIGKVPPPIPGVGKQLPP-SYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498
V PP L P S +P+P P S S+ + +LP P A PS+
Sbjct: 276 -------VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ--TLPSPPATPPSQA 326
Query: 499 R-----PTL------LPATGSTPQPGSSQQIQQRISVPP--SPTYPPAGPPAFPAGDSKP 545
PTL LP+ +P Q +++PP +P PPA PP P P
Sbjct: 327 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386
Query: 546 ELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPA-AHSALNKS 604
+ P +A+ A P P + P + +S S ATPP P+ A L
Sbjct: 387 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS---PSATPPSQAPPSLAAPPLQVP 443
Query: 605 VKAVYGKPVLPSGSTSP-SPLPFLHGSLSTGTPQPQ-PPSESTEKEPEQDGPAAPADGST 662
P+ PS + P +P P L P PQ PP+ +T P Q P+ PA
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT--PPLQALPSPPA---- 497
Query: 663 VESLP--RPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGP 720
S P P SP+ P+ SPL L L P ++ P P P
Sbjct: 498 --SFPGQAPFSPSASLPM--SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553
Query: 721 NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELP--PAQPT 778
+ TLA P SPS G D+ +++A EEL + P
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG--PDLAGHSSSATSTPEELRGYDSGPE 611
Query: 779 APLPAEPAPSSDANDNELPSPEPEELI---CPQTTHQTAE------PAEDNNNNVATVPT 829
A P P D EL + P P + A P + + T
Sbjct: 612 GGAAASPPP-----DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 666
Query: 830 TEQIPSPVAEAPSPGEEQVPPAPLPPAS-HPPATSTNKRTNLKKPNSERTG 879
+ P + P+PG + P P P S A + + P R G
Sbjct: 667 IYETEGPESATPAPG--ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 715
Score = 77.8 bits (190), Expect = 5e-14
Identities = 125/515 (24%), Positives = 193/515 (37%), Gaps = 83/515 (16%)
Query: 398 SSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSA--LGPTEKPGIEIGKVPPPIPGVG 455
++++ + AGA + P E + G + +P SA GPT PP G G
Sbjct: 42 AALRVLGAAGAVGRKPLAE---RAGGIGGATIPESAPRAGPTRTSR-------PPASGRG 91
Query: 456 KQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSS 515
++ PP+ T P P PG S R G L + + + + AT + + S
Sbjct: 92 ERAPPAKNTSPGPVS-SPGRASGTTR--PGPLGQKGLRISAEETVARGKATEAPKRSALS 148
Query: 516 QQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGP-QTV 574
++ S P T PA A ++ LP RP +RP+ P +GP ++V
Sbjct: 149 AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP-----RP---APSARPRPPTEGPRKSV 200
Query: 575 NSSSIYSMYLQQATPPKNYQPAAHSALN------------------KSVKAVYGKPVLPS 616
+S+S +S + +P +P+A L +S + G P P+
Sbjct: 201 SSASEHS--TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258
Query: 617 GSTSPSPLPFLHGSLSTGTPQPQPP-----------SESTEKEPEQDGPAAPADGSTVES 665
+ P P G + PQ PP S S P P +P+ ++++
Sbjct: 259 HPSQPKP----KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314
Query: 666 LPRP--LSPTKLTPIVHSPL-----RYQSDADLEALRRKLANAPRPLKKRSSITEPEGPG 718
LP P P++ T + SP + L L AP L P P
Sbjct: 315 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 374
Query: 719 GPNIQKLLY---QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGN-LEELPP 774
P + L Q N LA + PF P PS + + + + + PP
Sbjct: 375 SPPLSPLATPSPQAPNALAVHLLQAPF-SPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Query: 775 AQPTAPLPAEPAP--SSDANDNELPSPE-PEELICPQTTHQTAEPAEDNNNNVATVPTTE 831
+ PL P+P S + + P P+ P L P Q A+P +AT P +
Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL--QLAKPPPQAPPALAT-PPLQ 490
Query: 832 QIPSPVA----EAPSPGEEQVPPAPL--PPASHPP 860
+PSP A +AP +P +PL PP PP
Sbjct: 491 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525
>gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit
16A [Homo sapiens]
Length = 528
Score = 83.6 bits (205), Expect = 9e-16
Identities = 44/129 (34%), Positives = 71/129 (55%), Gaps = 3/129 (2%)
Query: 871 KKPNSERTGHGL--RVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNA 928
++P E GL +V F P +LL+A+ + + V++ + P N++G+T LH
Sbjct: 52 ERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGVSPDLANEDGLTALHQC 111
Query: 929 VCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDI 988
+V+ LL+ G N+NA DS+ WTPLH AA+C +HL + L+ SGA + A +D
Sbjct: 112 CIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVN-TDG 170
Query: 989 ETAADKCEE 997
D C++
Sbjct: 171 NMPYDLCDD 179
Score = 57.0 bits (136), Expect = 1e-07
Identities = 34/87 (39%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 913 DPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQ 972
D P D G T LH A G LL+ +++A D DGW PLH AA V L +
Sbjct: 224 DLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVEL 283
Query: 973 LVESGAAIFASTISDIETAADKCEEME 999
LV GA + A ++ D ET D C + E
Sbjct: 284 LVAHGADLNAKSLMD-ETPLDVCGDEE 309
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 83.2 bits (204), Expect = 1e-15
Identities = 132/551 (23%), Positives = 192/551 (34%), Gaps = 75/551 (13%)
Query: 330 TSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSL-SIASNAAHGRSKSANDGN 388
++ P SP + P +Q + + L P+ L +++S A+H +
Sbjct: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
Query: 389 WPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPF-SALGPTEKPGIEIGKV 447
P L+ SS + +Q A P +E S P P +A P P +E
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLEN-----LPSLAPPPLQTASAPLTTPHLETPPC 563
Query: 448 PPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSA-GLPSRQRPTLLPAT 506
P P P Q PPS T P P P S ++ + +L P GLPS P L P
Sbjct: 564 PAPCP---LQAPPSPLTTPPPET--PSSIATPPPQAPPALASPPLQGLPS---PPLSPL- 614
Query: 507 GSTPQPGSSQQIQQRISVPP--SPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRP 564
+TP P Q +++PP +P PPA PP P P+ P +A+ A P
Sbjct: 615 -ATPPP----QAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 565 QSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPL 624
P + P + +S S ATPP P+ A V PS SP
Sbjct: 670 SPPVQAPFSPPASPPVS---PSATPPSQAPPSL---------AAPPLQVPPSPPASPPMS 717
Query: 625 PFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLR 684
P +T PQ PP + + PA+P P+SP+ P PL
Sbjct: 718 P-----SATPPPQAPPPLAAPPLQVPPSPPASP-----------PMSPSATPPPRVPPL- 760
Query: 685 YQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQ 744
L A ++ +P S + +P P + Q + G +
Sbjct: 761 ------LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
Query: 745 PSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPL------PAEPAPSSDANDNEL-- 796
PS S L ++PP+ P +P P P P + + L
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
Query: 797 ---PSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPL 853
P P P P +T + A +++ +T S P G PP
Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS----GPEGGAAASPPPDA 930
Query: 854 P-PASHPPATS 863
A HP A S
Sbjct: 931 ELAACHPAAWS 941
Score = 74.7 bits (182), Expect = 4e-13
Identities = 119/493 (24%), Positives = 176/493 (35%), Gaps = 41/493 (8%)
Query: 428 PVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSL 487
P+P + P+ P ++ PP P Q PPS T P P P + + SL
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPP--SQAPPSMTTPPMQAP--PSLQTIPPIQVPHSL 395
Query: 488 PRPSAGLPSRQRPTLLPATGSTPQPGSS--QQIQQRISVPPSPTYPPAGPPAFPAG---D 542
PS P P L + +T GS Q +++ P T P+ PA D
Sbjct: 396 TSPSLQAPPS--PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
Query: 543 SKP-ELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQAT---------PPKN 592
S P + PL++ P L S SP P T++ S + PP
Sbjct: 454 SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE 513
Query: 593 YQPA-AHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQP-PSESTEKEPE 650
Q + A +L ++ P+ S +P PL L+T + P P+ + P
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573
Query: 651 QDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSS 710
P + + + P P +P L PL+ L L AP L
Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALAS---PPLQGLPSPPLSPLATPPPQAPPXLALPPL 630
Query: 711 ITEPEGPGGPNIQKLLY---QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANG 767
P P P + L Q N LA + PF P PS + + + +
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-SPPPSPPVQAPFSPPASPPVSPSA 689
Query: 768 NL-EELPPAQPTAPLPAEPAP--SSDANDNELPSPE-PEELICPQTTHQTAEPAEDNNNN 823
+ PP+ PL P+P S + + P P+ P L P + PA +
Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749
Query: 824 VATVP--TTEQIPSPVAEAPSPGEEQVPPAPL--PPASHPPATSTNKRTNLKKPNSERTG 879
AT P + +P + P +P +PL PP PPA +T L P + G
Sbjct: 750 SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809
Query: 880 HGLRVRFNPLALL 892
+ F+P A L
Sbjct: 810 ---QAPFSPSASL 819
Score = 68.6 bits (166), Expect = 3e-11
Identities = 125/490 (25%), Positives = 185/490 (37%), Gaps = 83/490 (16%)
Query: 398 SSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSA--LGPTEKPGIEIGKVP--PPIPG 453
++++ + AGA + P E + G + +P SA GPT G PP G
Sbjct: 42 AALRVLGAAGAVGRKPLAE---RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASG 98
Query: 454 VGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPG 513
G++ PP+ T P P PG S R G L + + + + AT + +
Sbjct: 99 RGERAPPAKNTSPGPVS-SPGRASGTTR--PGPLGQKGLRISAEETVARGKATEAPKRSA 155
Query: 514 SSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGP-Q 572
S ++ S P T PA A ++ LP RP +RP+ P +GP +
Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP-----RP---APSARPRPPTEGPRK 207
Query: 573 TVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPL--PFLHGS 630
+V+S+S +S + +P +P+A L +P S S+S +PL P G
Sbjct: 208 SVSSASEHS--TTEPSPAARRRPSAGGGLQ--------RPASRSLSSSATPLSSPARSGP 257
Query: 631 LSTGTP-------QPQPPSESTEKEPEQDGP---AAPADG---STVESLPRPLSPTKLTP 677
+ GTP QP+P + P+ P AAPA G S+ + P P S TK P
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-SGTKARP 316
Query: 678 IVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGM 737
+ D L L +P PL + P P++Q L
Sbjct: 317 VP------PPDNAATPLPATLPPSP-PLATPLPLAPPSPSAPPSLQTL---------PSP 360
Query: 738 EGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELP 797
TP Q PS + A +L+ +PP Q P S + +
Sbjct: 361 PATPPSQAPPS---------MTTPPMQAPPSLQTIPPIQ---------VPHSLTSPSLQA 402
Query: 798 SPEPEELICPQTTHQTAEPAEDNNNNVATV---PTTEQIPSPVAEAPSPGEEQVPPAPLP 854
P P L Q T P ++ T+ T + SP A +P + APL
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462
Query: 855 -PASHPPATS 863
PAS P TS
Sbjct: 463 LPASPPLQTS 472
Score = 31.6 bits (70), Expect = 4.3
Identities = 47/191 (24%), Positives = 68/191 (35%), Gaps = 24/191 (12%)
Query: 331 SSPQSPLSTSGRVAA---VGPYIQVP-SAGSFPVLGDPIKPQSLSIASNAAHGRSKSA-N 385
S P SPL+T A P +QVP S + P L P +P + ++ + R A
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877
Query: 386 DGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVK------QGTVSSQPVPFSALGPTEK 439
G P ++ SS++ +AG S ++ +G ++ P P + L
Sbjct: 878 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 937
Query: 440 PGIEIGKVPP----PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLP 495
G PP PG PP+ GPGS L E P + P
Sbjct: 938 AAWSRGPAPPLAFRGAPGAPLPWPPA---------TGPGSADGLCTIYETEGPESATPAP 988
Query: 496 SRQRPTLLPAT 506
P P T
Sbjct: 989 GALDPGPSPGT 999
Score = 31.2 bits (69), Expect = 5.6
Identities = 32/147 (21%), Positives = 48/147 (32%), Gaps = 12/147 (8%)
Query: 734 AGGMEGTPFYQPSPSQD---FMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSD 790
AGG+ G + +P GT + A+G E PPA+ T+P P +
Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
Query: 791 ANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP------- 843
P + I + T + E + + P PSP
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
Query: 844 --GEEQVPPAPLPPASHPPATSTNKRT 868
G E P P P A P T +++
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKS 208
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 82.4 bits (202), Expect = 2e-15
Identities = 156/616 (25%), Positives = 211/616 (34%), Gaps = 96/616 (15%)
Query: 329 GTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIAS-------NAAHGRS 381
GT SP + VG PSA P P K S+S AS + A R
Sbjct: 170 GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK--SVSSASEHSTTEPSPAARRR 227
Query: 382 KSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFS--------- 432
SA G ++ SSS P+ PS G+ + SQP P
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 433 ---------ALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYP----------SPTPLGP 473
ALGP + P P + Q PP+ P +P PL P
Sbjct: 286 TPPRKDAAPALGPLSSSPLA---TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQR-----PTL------LPATGSTPQPGSSQQIQQRI 522
S S+ + +LP P A PS+ PTL LP+ +P Q +
Sbjct: 343 PSPSAPPSLQ--TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
Query: 523 SVPP--SPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIY 580
++PP +P PPA PP P P+ P +A+ A P P + P + +S
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460
Query: 581 SMYLQQATPPKNYQPA-AHSALNKSVKAVYGKPVLPSGSTSP-SPLPFLHGSLSTGTPQP 638
S ATPP P+ A L P+ PS + P +P P L P P
Sbjct: 461 S---PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517
Query: 639 Q-PPSESTEKEPEQDGPAAPADGSTVESLP--RPLSPTKLTPIVHSPLRYQSDADLEALR 695
Q PP+ +T P Q P+ PA S P P SP+ P+ SPL L
Sbjct: 518 QAPPALAT--PPLQALPSPPA------SFPGQAPFSPSASLPM--SPLATPPPQAPPVLA 567
Query: 696 RKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTL 755
L P ++ P P P + TLA P SPS G
Sbjct: 568 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG-- 625
Query: 756 ADVDNGNTNANGNLEELP--PAQPTAPLPAEPAPSSDANDNELPSPEPEELI---CPQTT 810
D+ +++A EEL + P A P P D EL + P P
Sbjct: 626 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP-----DAELAACHPAAWSRGPAPPLA 680
Query: 811 HQTAE------PAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPAS-HPPATS 863
+ A P + + T + P + P+PG + P P P S A
Sbjct: 681 FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG--ALDPGPSPGTSGGKAAAG 738
Query: 864 TNKRTNLKKPNSERTG 879
+ + P R G
Sbjct: 739 AGAGASSRSPKQARLG 754
Score = 79.3 bits (194), Expect = 2e-14
Identities = 126/495 (25%), Positives = 188/495 (37%), Gaps = 83/495 (16%)
Query: 398 SSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSA--LGPTEKPGIEIGKVP--PPIPG 453
++++ + AGA + P E + G + +P SA GPT G PP G
Sbjct: 42 AALRVLGAAGAVGRKPLAE---RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASG 98
Query: 454 VGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPG 513
G++ PP+ T P P PG S R G L + + + + AT + +
Sbjct: 99 RGERAPPAKNTSPGPVS-SPGRASGTTR--PGPLGQKGLRISAEETVARGKATEAPKRSA 155
Query: 514 SSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGP-Q 572
S ++ S P T PA A ++ LP RP +RP+ P +GP +
Sbjct: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP-----RP---APSARPRPPTEGPRK 207
Query: 573 TVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPL--PFLHGS 630
+V+S+S +S + +P +P+A L +P S S+S +PL P G
Sbjct: 208 SVSSASEHS--TTEPSPAARRRPSAGGGLQ--------RPASRSLSSSATPLSSPARSGP 257
Query: 631 LSTGTP-------QPQPPSESTEKEPEQDGP---AAPADGSTVESLPRPLSPTKL-TPIV 679
+ GTP QP+P + P+ P AAPA G PLS + L TP
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG--------PLSSSPLATPSP 309
Query: 680 HSPLRYQSDADLEA------LRRKLAN-----APRPLKKRSSITEPEGPGGPNIQKLLYQ 728
+ L+ Q+ L A L +LA P P S T P P P Q
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
Query: 729 RFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPS 788
TL + T + PSP + T + PPA PL A P+P
Sbjct: 370 GSPTL----QATHSFLPSPPLSPLATPP-------------PQAPPALALPPLQAPPSPP 412
Query: 789 SDANDNELPSPEPEELICPQ--TTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEE 846
+ + L +P P+ P H P + P + PV+ + +P +
Sbjct: 413 ASPPLSPLATPSPQ---APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 469
Query: 847 QVPPAPLPPASHPPA 861
P PP PP+
Sbjct: 470 APPSLAAPPLQVPPS 484
Score = 31.2 bits (69), Expect = 5.6
Identities = 32/147 (21%), Positives = 48/147 (32%), Gaps = 12/147 (8%)
Query: 734 AGGMEGTPFYQPSPSQD---FMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSD 790
AGG+ G + +P GT + A+G E PPA+ T+P P +
Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
Query: 791 ANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP------- 843
P + I + T + E + + P PSP
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
Query: 844 --GEEQVPPAPLPPASHPPATSTNKRT 868
G E P P P A P T +++
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKS 208
>gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 16B
[Homo sapiens]
Length = 567
Score = 82.0 bits (201), Expect = 3e-15
Identities = 46/119 (38%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
Query: 879 GHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVK 938
G +V F LL+ASL + + V+ + P N++G+T LH IVK
Sbjct: 59 GRRKKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVK 118
Query: 939 FLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEE 997
LL G NVNA D++ WTPLH AA+C ++L K LV+ GA + A SD D CE+
Sbjct: 119 LLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN-SDGNMPYDLCED 176
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/80 (42%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 920 EGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAA 979
+G T LH A G+ + LLD GV V+ D DGW PLH AA + + + LV GA+
Sbjct: 228 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 287
Query: 980 IFASTISDIETAADKCEEME 999
+ A T D E D CEE E
Sbjct: 288 LSARTSMD-EMPIDLCEEEE 306
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 82.0 bits (201), Expect = 3e-15
Identities = 138/540 (25%), Positives = 190/540 (35%), Gaps = 94/540 (17%)
Query: 413 PSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPP--IPGVGKQLPPS-YGTYPSPT 469
PS +G + P +A P+ K G+ PPP P PPS G +P+
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLA---TPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 470 PLG-PGSTSSLERRKEGSLPRPSA-GLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPS 527
P G P + ++ +G L PS G P+ T G P + PPS
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250
Query: 528 P-----TYPPAGPPAFPAGDSKPELPLTVAIRPFL-----------ADKGSRPQSPRKGP 571
P T PP G P PA + P L +A P + KG SP KG
Sbjct: 1251 PKGGPATPPPKGAPTPPAA-TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309
Query: 572 QTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSL 631
T +++ S TPP P + S K G P LP+ + S P S
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK---GTPTLPATTPSSKGGPTTPSSK 1366
Query: 632 STGTPQPQPPSES-----TEKEPEQDGPAAPAD-GSTVESLPRPLSPTKL--TPIVHSPL 683
TP PS T P++ GPA P+ G PLSP K TP+
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKR-GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGA 1425
Query: 684 RYQSDADLEALRRKLANAPRPLKKRSSITEPEG-PGGPNIQKLLYQRFNTLAGGMEGTPF 742
S DL A P LKK + + P+G P P+ + TL +P
Sbjct: 1426 ATPSKGDLTPP----AVTPVSLKKAPATSAPKGGPATPSSKG-----DPTLPAVTPPSPK 1476
Query: 743 YQPSPSQDFMGTLADVDNGNTNANG----------NLEELP--------PAQPTAPLPAE 784
P+P Q + G + +E+P P PTA L ++
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536
Query: 785 PAPSSDANDNEL-------PSPEPEELI-CPQTTHQTAEPAEDNNNNVATVPTTEQIPSP 836
P++ A L PSP+ I P+ T E ++ T T + PSP
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596
Query: 837 -------VAEAPSPGEEQVPPAPLPP--------------ASHPPATSTNKRTNLKKPNS 875
+PSP E PPA PP + PP T ++ + + P S
Sbjct: 1597 KELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS 1656
Score = 80.1 bits (196), Expect = 1e-14
Identities = 138/562 (24%), Positives = 182/562 (32%), Gaps = 84/562 (14%)
Query: 331 SSPQS-PLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNW 389
SSP+ P SG A S G+ L D P +S++ +K + G
Sbjct: 765 SSPKECPTEDSGASATAS------SKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP- 817
Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449
T N SS V PV+ + S +GS + P P S G +
Sbjct: 818 DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT------ 871
Query: 450 PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGST 509
P+ G LPP +PTP S +L KEG P+ ++ L T S+
Sbjct: 872 PLSPKGVTLPPK----ETPTP----SVVNLPFPKEGP------ATPAPKQAPALSMTSSS 917
Query: 510 PQPGSSQQIQQRISVPPSPTY---PPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQS 566
P+ + + I PSP PPA P P G P P + P S
Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP-----AATPPS 972
Query: 567 PRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSA-LNKSVKAVYGKPVL--PSGSTSPSP 623
P+ GP T + TPP P+ S K P + PS SP+
Sbjct: 973 PKGGPATPSPKG-------APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025
Query: 624 LPFLHGSLSTGTPQPQPPSESTEKEPEQDG----PAA----PADGSTVESLPRPLSPTKL 675
PF G+ + P P S P G PAA P G SL +P
Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 676 TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQR-----F 730
TP P A + A P + + P G P
Sbjct: 1086 TP----PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141
Query: 731 NTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNA-------NGNLEELPPAQPTAPLPA 783
G TP P + + T T A G P PT P
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201
Query: 784 EPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843
P+P L +P P+ TT P+ +AT +P A PSP
Sbjct: 1202 PPSPKGG-----LATPSPKG---APTTPAATPPSP--KGGLATPSPKGAPTTPAATPPSP 1251
Query: 844 -GEEQVPP---APLPPASHPPA 861
G PP AP PPA+ PP+
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPS 1273
Score = 79.0 bits (193), Expect = 2e-14
Identities = 126/502 (25%), Positives = 181/502 (36%), Gaps = 79/502 (15%)
Query: 413 PSVEGSVKQGTVSSQPVPFSALGPTEK-----PGIEIGKVPP----PIPGVGKQLPPSYG 463
PS +G ++ P P +A P+ K P + +PP P P G PP G
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124
Query: 464 --TYPSPTPLGPGSTSSLERRK------EGSLPRPSAGL---PSRQRPTLLPATGSTPQP 512
T P+ TP P + K + P P GL P + PT AT +P+
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184
Query: 513 GSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPE---LPLTVAIRPFLADKGSRPQSPRK 569
G + S +PT P A PP+ G + P P T A P G SP K
Sbjct: 1185 GLATP-----SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP-K 1238
Query: 570 GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVL-----PSGSTSPSPL 624
G T +++ S ATPP P +A S+K P P+ T PSP
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP- 1297
Query: 625 PFLHGSLSTGTPQPQP-PSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPL 683
G +T P+ P P +T P+ P G+ P SP K TP +
Sbjct: 1298 ---KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP-KGTPTLP--- 1350
Query: 684 RYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFY 743
A P ++ + EGP P + GG TP
Sbjct: 1351 ---------------ATTPSSKGGPTTPSSKEGPTPPAATP-------SHKGGPAMTP-- 1386
Query: 744 QPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEE 803
PSP + G G+ + + P P P+ E A + D P+ P
Sbjct: 1387 -PSPKR---GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 804 LI-CPQTTHQTAEPAEDNNNN-----VATVPTTEQIPSP--VAEAPSPGEEQVPPAPLPP 855
L P T+ PA ++ T P+ ++ P+P VA + SP + PAP+
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Query: 856 ASHPPATSTNKRTNLKKPNSER 877
+ P ++ + P+S R
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRR 1524
Score = 64.7 bits (156), Expect = 5e-10
Identities = 142/596 (23%), Positives = 202/596 (33%), Gaps = 103/596 (17%)
Query: 337 LSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNS 396
L+T A P + P + P G P + AA S + G P +
Sbjct: 1278 LATPPHKGAPNPAVVTPPS---PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334
Query: 397 SSSVKPVQVAGADW---KDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPG 453
+V P G PS +G + P P +A P+ K G + PP P
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT-PSHKGG---PAMTPPSPK 1390
Query: 454 VGKQLPPSYG--TYPSPTPLGPGSTSSLERRKEGSLPRPSAG--LPSRQRPTLL---PAT 506
G +P G T P+ PL P + +EG+ PS G P P L PAT
Sbjct: 1391 RGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT-PSKGDLTPPAVTPVSLKKAPAT 1449
Query: 507 ----GSTPQPGSSQQIQQRISVPPSPTYPPAGP-----------PAFPAGDSKPELPLTV 551
G P S PPSP PPA PA PA P LP +
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509
Query: 552 AIRPFLADKGSRPQSPRKGPQTVNSS----SIYSMYLQQATP----PKN--YQPAAHSAL 601
P SP++ P T +S + + L + TP PK PA
Sbjct: 1510 ------------PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 602 NKSVKAV---YGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQ----PPSESTEKEPE---- 650
K A+ P PS + SP P + S G P P+ PP+ ++ E
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
Query: 651 --------QDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAP 702
+ GPA PA T S P S K +P + + + A + + L
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK 1676
Query: 703 RPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFY-QPSPSQDFMGTLADV--- 758
P + + P P I + T P PS G L+ V
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA 1736
Query: 759 ------DNGNTNANGNLEELPPAQPTAPLPAEPAP--SSDANDNELPSPEPEELICPQTT 810
+ + A G P P AP ++ + ++ A + LP PE + +
Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP 1796
Query: 811 HQTAEPAEDNNNNVATVPTTEQI----PSPVAEAPS----PGEEQ-----VPPAPL 853
+ A + V T+P +Q P V E+PS P +E +PP P+
Sbjct: 1797 PVSLPLAP---SPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPI 1849
Score = 60.1 bits (144), Expect = 1e-08
Identities = 92/367 (25%), Positives = 133/367 (36%), Gaps = 78/367 (21%)
Query: 332 SPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPT 391
S ++P + + + A + P + VPS P + P + + P+
Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT-------------------PS 1575
Query: 392 LKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQP--VPFSALGPTEKPGIEIGKVPP 449
K+ SS P+V S +G S + +P + P+ K V P
Sbjct: 1576 SKEASSP--------------PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621
Query: 450 PIPGVGKQLPPSYGTYPSP--TPLG----PGSTSSLERRKEGSLPRPSAGLPSRQRPTLL 503
P P G P GT SP TP P S +S+ + ++P+ S GLP+++ PT L
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL 1681
Query: 504 PATGSTPQPGSSQQIQQRISVPP-----SPTYPPAGPPAFPAGDSKPELPLTVAIRPFL- 557
P P S+ I P S T PP P SK L TVA P L
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS-TVAPAPLLP 1740
Query: 558 -----------ADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVK 606
D P+ P P++ S+ + + ++ P + SV
Sbjct: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPE---------SASVS 1791
Query: 607 AVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESL 666
A PV S +PSP+P L P ES K P APAD + L
Sbjct: 1792 AAPSPPV--SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSK------PLAPADEDELLPL 1843
Query: 667 --PRPLS 671
P P+S
Sbjct: 1844 IPPEPIS 1850
Score = 50.1 bits (118), Expect = 1e-05
Identities = 137/582 (23%), Positives = 206/582 (35%), Gaps = 141/582 (24%)
Query: 332 SPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPT 391
SPQ+P G ++ GP + P+A S P+ S A + +
Sbjct: 257 SPQNP----GSLSLKGP-VSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAP 311
Query: 392 LKQNSSSSVKPV-QVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPP 450
L Q+S SV+ + Q + DP+V+ T+S A P+++ V PP
Sbjct: 312 LHQSSFGSVQLLGQTGPSALSDPTVK------TISVDHSSTGASYPSQR------SVIPP 359
Query: 451 IPGVGKQLPPSYGTYPSPTPL---GPGSTSSLERRKEGSL---------PRPSAGLPSRQ 498
+P + +P + +P P GP + SS+ GSL P S L S
Sbjct: 360 LPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSP 419
Query: 499 RPTL---------LPATGSTPQPGSSQQIQQRISVPPSPTYPPA---GPP--AFPAGDSK 544
T + + G+TP ++ I+ P+ T+ A PP + P + +
Sbjct: 420 NATYHYPLVAQMPVSSVGTTPLVVTNPCT---IAAAPTTTFEVATCVSPPMSSGPISNIE 476
Query: 545 PELPLTVAIRPFLADKGSR--------PQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPA 596
P P + + P + S P SP P + ++ S L + K+ Q
Sbjct: 477 PTSPAALVMAPVAPKEPSTQVATTLRIPVSPPL-PDPEDLKNLPSSVLVKFPTQKDLQTV 535
Query: 597 AHSALNKSVKAVYGKPVLPS--GSTS---PSPLPFLHGSLSTGTPQPQPPSESTEKEPEQ 651
S + G P P+ G T+ P+ LP + + P+ P +ST PE
Sbjct: 536 PAS--------LEGAPFSPAQAGLTTKKDPTVLPLVQAA-----PKNSPSFQSTSSSPEI 582
Query: 652 DGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLA-NAPRPLKKRSS 710
P +P +SL PL K + SPL S A + ++ PL K S
Sbjct: 583 --PLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSL 640
Query: 711 IT--------EPEGPGG--PNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDN 760
IT E P G P K GT Y + S GT++
Sbjct: 641 ITPTVAAFPLESADPAGVAPTTAK--------------GTSTYTTTASPFLEGTVSLAPK 686
Query: 761 GNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDN 820
+ G L LP PTA ++N +P P+ P
Sbjct: 687 NHPVKEGTLTTLPLV-PTA------------SENCPVAPSPQNTCAP------------- 720
Query: 821 NNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPAT 862
+AT+ +IP V PSP LPPA PP T
Sbjct: 721 ---LATLVLAPEIPKSV---PSPS--------LPPAGTPPGT 748
Score = 37.0 bits (84), Expect = 0.10
Identities = 49/216 (22%), Positives = 78/216 (36%), Gaps = 48/216 (22%)
Query: 473 PGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPP 532
PG + E LP+P A + L T + QPG PT PP
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPG--------------PTLPP 47
Query: 533 AGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATP--- 589
P + + PL+ A SP P T+ S+ + + Q ++
Sbjct: 48 ------PCSPAPQQCPLSAA----------NQASPFPSPSTIASTPLEVPFPQSSSGTAL 91
Query: 590 PKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPL--PFLHGSLSTGTP------QPQPP 641
P P A + L + G P+ P+ SP+ P L G+ S+ P P
Sbjct: 92 PLGTAPEAPTFLPNLI----GPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSV 147
Query: 642 SESTEKEPE---QDGPAAPADGSTVESLPRPLSPTK 674
+S+ P A A+ +V +L P++P++
Sbjct: 148 QKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSE 183
Score = 32.7 bits (73), Expect = 1.9
Identities = 25/94 (26%), Positives = 37/94 (39%), Gaps = 14/94 (14%)
Query: 781 LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA 840
+P E + A + ELP P+ E + P ++ +V P P
Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPM-------------SSALSVTAALGQPGPTLPP 47
Query: 841 P-SPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873
P SP +Q P + AS P+ ST T L+ P
Sbjct: 48 PCSPAPQQCPLSAANQASPFPSPSTIASTPLEVP 81
Score = 30.4 bits (67), Expect = 9.5
Identities = 59/233 (25%), Positives = 87/233 (37%), Gaps = 44/233 (18%)
Query: 413 PSVEGSVKQGTVSSQPVPFS-ALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPL 471
P+ E + Q + +P S AL T G +PPP +Q P S SP P
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFP- 68
Query: 472 GPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYP 531
P + +S E P+ S+G T LP + P +PT+
Sbjct: 69 SPSTIASTP--LEVPFPQSSSG-------TALPLG----------------TAPEAPTFL 103
Query: 532 P--AGPPAFPAGDSKPELPLTVAIRPFLAD--KGSRPQSPRKGPQTVNSSSIYSMYLQQA 587
P GPP PA L +A P +A KG+ S P + + + +S+ A
Sbjct: 104 PNLIGPPISPAA-------LALA-SPMIAPTLKGTPSSS---APLALVALAPHSVQKSSA 152
Query: 588 TPPKNYQPAAHSALNKSVKAV-YGKPVLPS-GSTSPSPLPFLHGSLSTGTPQP 638
PP A+ +S + P+ PS T+ + +P GTP P
Sbjct: 153 FPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP 205
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 77.0 bits (188), Expect = 9e-14
Identities = 48/135 (35%), Positives = 77/135 (57%), Gaps = 5/135 (3%)
Query: 868 TNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHN 927
T+L+ P +R +V+F+ A+ L A G+ D V ++++ D + N +G+T LH
Sbjct: 22 TDLEPPVVKR--QKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQ 79
Query: 928 AVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISD 987
A + +VKFL++ G N+N D++GW PLH AASC + + + L+ GA + A S+
Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SE 138
Query: 988 IETAADKCEE--MEE 1000
+T D EE MEE
Sbjct: 139 GDTPLDIAEEEAMEE 153
Score = 55.1 bits (131), Expect = 4e-07
Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 8/175 (4%)
Query: 836 PVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDA 895
P+ A S G + + +H A ++ T L E L+ N + ++A
Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEA 168
Query: 896 SLEGEFDLVQRIIYEVEDPSKPND-----EGITPLHNAVCAGHHHIVKFLLDFGVNVNAA 950
+ + E ++ R + + ND G T LH A G+ ++K L+ G +VN
Sbjct: 169 ARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIK 228
Query: 951 DSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDI-ETAADKCEEMEEGYIQ 1004
D DGWTPLH AA C+ LV++ + ++ + +TA D +E GY++
Sbjct: 229 DYDGWTPLHAAAHWGKEEACRILVDNLCDM--EMVNKVGQTAFDVADEDILGYLE 281
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit 12A
isoform a [Homo sapiens]
Length = 1030
Score = 77.0 bits (188), Expect = 9e-14
Identities = 48/135 (35%), Positives = 77/135 (57%), Gaps = 5/135 (3%)
Query: 868 TNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHN 927
T+L+ P +R +V+F+ A+ L A G+ D V ++++ D + N +G+T LH
Sbjct: 22 TDLEPPVVKR--QKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQ 79
Query: 928 AVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISD 987
A + +VKFL++ G N+N D++GW PLH AASC + + + L+ GA + A S+
Sbjct: 80 ACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SE 138
Query: 988 IETAADKCEE--MEE 1000
+T D EE MEE
Sbjct: 139 GDTPLDIAEEEAMEE 153
Score = 55.1 bits (131), Expect = 4e-07
Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 8/175 (4%)
Query: 836 PVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDA 895
P+ A S G + + +H A ++ T L E L+ N + ++A
Sbjct: 109 PLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEA 168
Query: 896 SLEGEFDLVQRIIYEVEDPSKPND-----EGITPLHNAVCAGHHHIVKFLLDFGVNVNAA 950
+ + E ++ R + + ND G T LH A G+ ++K L+ G +VN
Sbjct: 169 ARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIK 228
Query: 951 DSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDI-ETAADKCEEMEEGYIQ 1004
D DGWTPLH AA C+ LV++ + ++ + +TA D +E GY++
Sbjct: 229 DYDGWTPLHAAAHWGKEEACRILVDNLCDM--EMVNKVGQTAFDVADEDILGYLE 281
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 76.6 bits (187), Expect = 1e-13
Identities = 42/115 (36%), Positives = 66/115 (57%), Gaps = 1/115 (0%)
Query: 883 RVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLD 942
RVRF A+ L A G+ D V++++ D + N +G+T LH A + +VKFL++
Sbjct: 53 RVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVE 112
Query: 943 FGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEE 997
NVN D++GWTPLH AASC +++ + + GA++ S+ E +D EE
Sbjct: 113 NRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV-GIVNSEGEVPSDLAEE 166
Score = 49.3 bits (116), Expect = 2e-05
Identities = 22/56 (39%), Positives = 29/56 (51%)
Query: 921 GITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVES 976
G T LH A G+ +++ L+ G +N D DGWTPLH AA C L E+
Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEA 272
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform a [Homo sapiens]
Length = 982
Score = 76.6 bits (187), Expect = 1e-13
Identities = 42/115 (36%), Positives = 66/115 (57%), Gaps = 1/115 (0%)
Query: 883 RVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLD 942
RVRF A+ L A G+ D V++++ D + N +G+T LH A + +VKFL++
Sbjct: 53 RVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVE 112
Query: 943 FGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEE 997
NVN D++GWTPLH AASC +++ + + GA++ S+ E +D EE
Sbjct: 113 NRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV-GIVNSEGEVPSDLAEE 166
Score = 49.3 bits (116), Expect = 2e-05
Identities = 22/56 (39%), Positives = 29/56 (51%)
Query: 921 GITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVES 976
G T LH A G+ +++ L+ G +N D DGWTPLH AA C L E+
Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEA 272
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 72.0 bits (175), Expect = 3e-12
Identities = 129/572 (22%), Positives = 193/572 (33%), Gaps = 102/572 (17%)
Query: 351 QVPSAGSFPVLGDPIKPQS----LSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVA 406
Q P G P+ G PQ+ L + +A+ ++K A+ ++K + S KP
Sbjct: 250 QPPGTGK-PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308
Query: 407 GADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYP 466
K P+ + ++ P G T+ + G V PP+ G PP+
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ---- 364
Query: 467 SPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTP--QPGSSQQIQQRISV 524
PLGP + + E +PS+ P + P G TP QPG
Sbjct: 365 ---PLGPAKPPAQQTGSE----KPSSEQPGPKALAQPPGVGKTPAQQPG----------- 406
Query: 525 PPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYL 584
PA PP G KP +A +P L QSP K P + +
Sbjct: 407 -------PAKPPTQQVGTPKP-----LAQQPGL-------QSPAKAPGPTKTP------V 441
Query: 585 QQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPS-PLPFLHGSLSTGTPQP---QP 640
QQ P K PA + K+ G PS P+ P P G QP +P
Sbjct: 442 QQPGPGKI--PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499
Query: 641 PSE---STEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRK 697
PS+ ST+ P+Q GPA P+ + P P P P + A
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
Query: 698 LANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT---LAGGMEGTPFYQPSPSQDFMGT 754
+ +PL+ + + P + K + NT L E F + Q + +
Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619
Query: 755 LADVDNGNTNANGNLEELP--------------------PAQPTAPLPAEPAPSSDANDN 794
L N N +L E+ P+ P L P ++ A
Sbjct: 620 LC-----GFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSK 674
Query: 795 ELPSPE---PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAP-------SPG 844
P P+ P++ P+ A P + PT PS A+ P P
Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKA-PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 845 EEQVPPAPLPPASHPPATSTNKRTNLKKPNSE 876
+ P P P A K+ + KP ++
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTD 765
Score = 61.6 bits (148), Expect = 4e-09
Identities = 99/461 (21%), Positives = 153/461 (33%), Gaps = 58/461 (12%)
Query: 460 PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQ 519
PS+ P+ S ERR+ ++ + GLP P PA +P Q++
Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP---PAAAESPSMHRKQELD 88
Query: 520 QRISVPPSPTYPPAGPPAFPAGD---------SKPELPLTVAIRPFLADKGSRPQSPRKG 570
S P G PA P S+ +LP L + SR +
Sbjct: 89 SSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEH 148
Query: 571 PQT--------VNSSSIYSMYLQQATPPK--NYQPAAHSALNKSVKAVYGKPVLPSG--- 617
+ VN+ S S + + P + A+ K K V + P G
Sbjct: 149 KSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208
Query: 618 ----STSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPT 673
P P+P G Q P + ++PE+ P G ++ PT
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ------GPT 262
Query: 674 KLTPIVHSPLRYQSDA------DLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLY 727
+ H+ L Q DA + +R + P + I +P PG P Q+ +
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT-PGKPPAQQPGH 321
Query: 728 QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAP 787
++ P P GT+ + L PA+P A P
Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 788 SSDANDNELPSPEPEELICP----QTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843
SS+ P P+ L P +T Q PA+ V T Q P + A +P
Sbjct: 382 SSE-------QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434
Query: 844 GEEQVP-----PAPLPPASHPPATSTNKRTNLKKPNSERTG 879
G + P P +P P ++ ++T KP S+ G
Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475
Score = 61.6 bits (148), Expect = 4e-09
Identities = 149/723 (20%), Positives = 246/723 (34%), Gaps = 126/723 (17%)
Query: 243 EDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQ--QKELLNKRN 300
E+ K + GF S L+ ++V K +L ++ +QE+ +K Q+ QKE
Sbjct: 146 EEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG 205
Query: 301 MEVAMMDKRISELRERLYGKKIQLNRVNGTS---SPQSPLSTSGRVAAVGPYIQVPSA-- 355
+ + ++ + + G + +GT S Q P + G IQ P+
Sbjct: 206 IIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP 265
Query: 356 ----GSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWK 411
P+ D +PQ+ S + P ++Q + P Q G +
Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK-PPAQQPGHEKS 324
Query: 412 DPSVEGSVKQGTVSSQPV---------PFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSY 462
P Q + ++P+ P G T+ P +G PP G + P S
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384
Query: 463 GTYPSPT--PLGPGSTSSLER------RKEGSLPRPSAGLPSRQRPTLLPATGSTPQ--- 511
P P G G T + + ++ P+P A P Q P P TP
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 512 -----------PGSSQQIQQRISVPPS---------PTYP-PAGPPAFPAGDSKPELPLT 550
PG + Q + PPS P P PA PP G +KP
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
Query: 551 VAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYG 610
+ +P G SP++ T S A P +P+A + + G
Sbjct: 505 GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564
Query: 611 KPVLPSGSTSPSPLPFLHGSLSTGTP----------QPQPPSESTEKEPE---------- 650
KP+ P + + P G T P P+ + +T E +
Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624
Query: 651 ----------------QDGPAAPADGSTVESLPRP---LSPTKLTPIV--HSPLRYQSDA 689
Q A D + V S P+P +P T V SP Q+
Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP 684
Query: 690 DLEAL-RRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPS-P 747
+A ++ L+ AP P K + +P G P+ + ++L+ + P +PS P
Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS---KPAPPKEPSVP 741
Query: 748 SQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPE-PEELIC 806
S+ +AD +P P +P ++ + P+ P +
Sbjct: 742 SEQDKAPVAD-----------------DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 807 PQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPA---SHPPATS 863
Q +T P + + + ++ P P E SP + + P P + SHP +S
Sbjct: 785 SQAEEKTTPPLKTD-----SAKPSQSFP-PTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 864 TNK 866
+K
Sbjct: 839 ESK 841
Score = 52.0 bits (123), Expect = 3e-06
Identities = 92/392 (23%), Positives = 129/392 (32%), Gaps = 91/392 (23%)
Query: 489 RPSAGLPSRQRPTLLPAT-GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPEL 547
+P +P +Q P P TP+ SSQQ ++ S PP P GP P D +L
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA-KL 272
Query: 548 PLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKA 607
PL SRPQ+ K V S+
Sbjct: 273 PLQ--------RDASRPQT--KQADIVRGESV---------------------------- 294
Query: 608 VYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLP 667
KP LPS S P P TP +PP++ E Q GPA P + + P
Sbjct: 295 ---KPSLPSPSKPPIQQP---------TPG-KPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341
Query: 668 RPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLY 727
P + P V P + A + L A P ++ S GP K L
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPA------QPLGPAKPPAQQTGSEKPSSEQPGP---KALA 392
Query: 728 QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAP 787
Q G+ TP QP P A +++ +P A P +P
Sbjct: 393 Q-----PPGVGKTPAQQPGP-----------------AKPPTQQVGTPKPLAQQPGLQSP 430
Query: 788 SSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQ 847
+ + P +P P Q A P + + Q+P P P +Q
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPA---QQAGPGKTSAQQTGPTKPPSQLPGPAKPPP----QQ 483
Query: 848 VPPAPLPPASHPPATSTNKRTNLKKPNSERTG 879
PA PP A +++ KP ++ G
Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG 515
Score = 50.8 bits (120), Expect = 7e-06
Identities = 89/416 (21%), Positives = 146/416 (35%), Gaps = 60/416 (14%)
Query: 466 PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA-TGSTPQPGSSQQIQQRISV 524
P P P ++ ++ P P P ++PTL + + QP + + +
Sbjct: 677 PQPQQTSPKKDAA-PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK--PA 733
Query: 525 PPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYL 584
PP P+ P D KP+ P V L S P + SS + S
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP-----DIPSSKVQSQAE 788
Query: 585 QQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSES 644
++ TPP +K KP T PF ++ P+P S+S
Sbjct: 789 EKTTPP--------------LKTDSAKPSQSFPPTGEKVSPFDSKAI------PRPASDS 828
Query: 645 TEKEPEQDGPAAPADGST-VESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPR 703
K GP++ + G V+ + + P K + + + DA PR
Sbjct: 829 --KIISHPGPSSESKGQKQVDPVQKKEEPKK----AQTKMSPKPDAKPMPKGSPTPPGPR 882
Query: 704 PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQD-----FMGTLADV 758
P ++ T + P P Q +RF+ G + P QP+ Q+ G A +
Sbjct: 883 PTAGQTVPTPQQSPK-PQEQS---RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI 938
Query: 759 DNGNTNANGNLEELPPAQPTAP-LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPA 817
+ +N + P + P P + AP+ PS P P++T Q A PA
Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAPA--------PSQPPTSQGPPKSTGQ-APPA 989
Query: 818 EDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873
++P ++ +P AE P EQ P P + ++ +P
Sbjct: 990 P-----AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040
Score = 50.1 bits (118), Expect = 1e-05
Identities = 95/457 (20%), Positives = 155/457 (33%), Gaps = 83/457 (18%)
Query: 396 SSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG 455
S SS +P Q + KD + + + + +P P K PP +
Sbjct: 673 SKSSPQPQQTSPK--KDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS 730
Query: 456 KQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSS 515
K PP + PS P + ++ K+ + +P+ L S T P P
Sbjct: 731 KPAPPKEPSVPSEQDKAPVAD---DKPKQPKMVKPTTDLVSSSSATTKP---DIPSSKVQ 784
Query: 516 QQIQQRISVP-------PSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPR 568
Q +++ + P PS ++PP G P DSK +P + ++ G P S
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-DSKA-IPRPASDSKIISHPG--PSSES 840
Query: 569 KGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLH 628
KG + V+ +Q+ PK Q K KP+ T P P P
Sbjct: 841 KGQKQVDP-------VQKKEEPKKAQ-------TKMSPKPDAKPMPKGSPTPPGPRPTAG 886
Query: 629 GSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSD 688
++ T P+P +S L I +P + Q
Sbjct: 887 QTVPTPQQSPKPQEQSRR------------------------FSLNLGSITDAP-KSQPT 921
Query: 689 ADLEALRRKLANAPRPL-KKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQ-PS 746
E + KL + + S++ G GP+ Q G P Q P+
Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ------------SGPGAPMKQAPA 969
Query: 747 PSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELIC 806
PSQ G + G + PPA P +P + + A + P E +
Sbjct: 970 PSQ------PPTSQGPPKSTG---QAPPA-PAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 807 PQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843
T + P +D+ + A P +P+ + ++P P
Sbjct: 1020 RTETEKKPPPIKDSKSLTAE-PQKAVLPTKLEKSPKP 1055
Score = 39.3 bits (90), Expect = 0.020
Identities = 56/231 (24%), Positives = 81/231 (35%), Gaps = 43/231 (18%)
Query: 495 PSRQRPTLLPATGSTP---QPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551
P+ Q P+ P+ S P +P + PP P PP PP P P LP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 552 AIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVY-- 609
+ +P + K L A+P P + AV
Sbjct: 2432 SPKPTILPKKK---------------------LTVASPVTTATPLFDAVTTLETTAVLRS 2470
Query: 610 -GKPVLPSGSTSPSPLPFLHGSLSTG---TPQPQPPSESTEKEPEQDGPAAPADGSTVES 665
G PV +T+P P+P S+ +G T +P+P K P P P +T +
Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEP-----SKPPIAPKPVIPQLPTTTQK 2525
Query: 666 LPRPL--SPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEP 714
P + PT L+ L + AD KL + PL S+ + P
Sbjct: 2526 -PTDIHPKPTGLSLTSSMTLNLVTSADY-----KLPSPTSPLSPHSNKSSP 2570
Score = 38.5 bits (88), Expect = 0.035
Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 18/133 (13%)
Query: 137 RQQQQIENQQQMLVA---KEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKI 193
+QQQQ++ ++++L K+QR + ER++ Q E EK+ K KL+++
Sbjct: 3209 KQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQK--------KLEEL 3260
Query: 194 RAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQL-EDLKKGKLNG 252
++M+ + + + E + M QE + Q + ++ QL QQL + L++ K+
Sbjct: 3261 QSMKQHLLFQQ------EEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314
Query: 253 FQSYNGKLTGPAA 265
YN +G A+
Sbjct: 3315 IYQYNYDPSGTAS 3327
Score = 32.7 bits (73), Expect = 1.9
Identities = 35/156 (22%), Positives = 51/156 (32%), Gaps = 17/156 (10%)
Query: 773 PPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQ 832
PP P P P P P + P+ P++ + + TA P D + T
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRS 2470
Query: 833 IPSPVAEAPSPGEEQVPPAP-----------LPPASHPPATSTNKRTNLKKPNSERTGHG 881
PV + VPP P P S PP L + T
Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD-- 2528
Query: 882 LRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKP 917
+ P L L +S+ +LV Y++ P+ P
Sbjct: 2529 --IHPKPTGLSLTSSM--TLNLVTSADYKLPSPTSP 2560
Score = 32.0 bits (71), Expect = 3.3
Identities = 28/104 (26%), Positives = 34/104 (32%), Gaps = 3/104 (2%)
Query: 773 PPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEP---AEDNNNNVATVPT 829
PP P P P P P P P+ I P+ A P A + V T+ T
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 830 TEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873
T + S PP P P+S P R KP
Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKP 2508
Score = 31.2 bits (69), Expect = 5.6
Identities = 56/226 (24%), Positives = 81/226 (35%), Gaps = 31/226 (13%)
Query: 417 GSVKQGTVSSQPVPF---SALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGP 473
GS ++ ++P PF S+L + +P PPP P PP P P P P
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQP-----PPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA 533
T +++ + P +A P T L T G RI P PP
Sbjct: 2434 KPTILPKKKLTVASPVTTA-TPLFDAVTTLETTAVLRSNGLP---VTRICTTAPPPVPPK 2489
Query: 534 GPPAFPAG-----DSKPELPLTVAIRPFLADKGSRPQSPRK-GPQTVNSSSIYSMYLQQA 587
P + P+G +P P +A +P + + Q P P+ S SM L
Sbjct: 2490 -PSSIPSGLVFTHRPEPSKP-PIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547
Query: 588 TPPKNYQPAAHSAL-----------NKSVKAVYGKPVLPSGSTSPS 622
T P+ S L +KS+ Y LPS +P+
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPT 2593
Score = 30.4 bits (67), Expect = 9.5
Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 6/74 (8%)
Query: 794 NELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPL 853
++LPS P P A+P ++ + P P P P PP PL
Sbjct: 2374 SQLPSGSPSVSSLP------AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427
Query: 854 PPASHPPATSTNKR 867
PP + P T K+
Sbjct: 2428 PPPTSPKPTILPKK 2441
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 72.0 bits (175), Expect = 3e-12
Identities = 129/572 (22%), Positives = 193/572 (33%), Gaps = 102/572 (17%)
Query: 351 QVPSAGSFPVLGDPIKPQS----LSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVA 406
Q P G P+ G PQ+ L + +A+ ++K A+ ++K + S KP
Sbjct: 250 QPPGTGK-PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308
Query: 407 GADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYP 466
K P+ + ++ P G T+ + G V PP+ G PP+
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ---- 364
Query: 467 SPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTP--QPGSSQQIQQRISV 524
PLGP + + E +PS+ P + P G TP QPG
Sbjct: 365 ---PLGPAKPPAQQTGSE----KPSSEQPGPKALAQPPGVGKTPAQQPG----------- 406
Query: 525 PPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYL 584
PA PP G KP +A +P L QSP K P + +
Sbjct: 407 -------PAKPPTQQVGTPKP-----LAQQPGL-------QSPAKAPGPTKTP------V 441
Query: 585 QQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPS-PLPFLHGSLSTGTPQP---QP 640
QQ P K PA + K+ G PS P+ P P G QP +P
Sbjct: 442 QQPGPGKI--PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499
Query: 641 PSE---STEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRK 697
PS+ ST+ P+Q GPA P+ + P P P P + A
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
Query: 698 LANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNT---LAGGMEGTPFYQPSPSQDFMGT 754
+ +PL+ + + P + K + NT L E F + Q + +
Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619
Query: 755 LADVDNGNTNANGNLEELP--------------------PAQPTAPLPAEPAPSSDANDN 794
L N N +L E+ P+ P L P ++ A
Sbjct: 620 LC-----GFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSK 674
Query: 795 ELPSPE---PEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAP-------SPG 844
P P+ P++ P+ A P + PT PS A+ P P
Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKA-PEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 845 EEQVPPAPLPPASHPPATSTNKRTNLKKPNSE 876
+ P P P A K+ + KP ++
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTD 765
Score = 61.6 bits (148), Expect = 4e-09
Identities = 99/461 (21%), Positives = 153/461 (33%), Gaps = 58/461 (12%)
Query: 460 PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQ 519
PS+ P+ S ERR+ ++ + GLP P PA +P Q++
Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP---PAAAESPSMHRKQELD 88
Query: 520 QRISVPPSPTYPPAGPPAFPAGD---------SKPELPLTVAIRPFLADKGSRPQSPRKG 570
S P G PA P S+ +LP L + SR +
Sbjct: 89 SSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEH 148
Query: 571 PQT--------VNSSSIYSMYLQQATPPK--NYQPAAHSALNKSVKAVYGKPVLPSG--- 617
+ VN+ S S + + P + A+ K K V + P G
Sbjct: 149 KSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208
Query: 618 ----STSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPT 673
P P+P G Q P + ++PE+ P G ++ PT
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ------GPT 262
Query: 674 KLTPIVHSPLRYQSDA------DLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLY 727
+ H+ L Q DA + +R + P + I +P PG P Q+ +
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT-PGKPPAQQPGH 321
Query: 728 QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAP 787
++ P P GT+ + L PA+P A P
Sbjct: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381
Query: 788 SSDANDNELPSPEPEELICP----QTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843
SS+ P P+ L P +T Q PA+ V T Q P + A +P
Sbjct: 382 SSE-------QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434
Query: 844 GEEQVP-----PAPLPPASHPPATSTNKRTNLKKPNSERTG 879
G + P P +P P ++ ++T KP S+ G
Sbjct: 435 GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475
Score = 61.6 bits (148), Expect = 4e-09
Identities = 149/723 (20%), Positives = 246/723 (34%), Gaps = 126/723 (17%)
Query: 243 EDLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQ--QKELLNKRN 300
E+ K + GF S L+ ++V K +L ++ +QE+ +K Q+ QKE
Sbjct: 146 EEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG 205
Query: 301 MEVAMMDKRISELRERLYGKKIQLNRVNGTS---SPQSPLSTSGRVAAVGPYIQVPSA-- 355
+ + ++ + + G + +GT S Q P + G IQ P+
Sbjct: 206 IIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTP 265
Query: 356 ----GSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWK 411
P+ D +PQ+ S + P ++Q + P Q G +
Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK-PPAQQPGHEKS 324
Query: 412 DPSVEGSVKQGTVSSQPV---------PFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSY 462
P Q + ++P+ P G T+ P +G PP G + P S
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384
Query: 463 GTYPSPT--PLGPGSTSSLER------RKEGSLPRPSAGLPSRQRPTLLPATGSTPQ--- 511
P P G G T + + ++ P+P A P Q P P TP
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
Query: 512 -----------PGSSQQIQQRISVPPS---------PTYP-PAGPPAFPAGDSKPELPLT 550
PG + Q + PPS P P PA PP G +KP
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
Query: 551 VAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYG 610
+ +P G SP++ T S A P +P+A + + G
Sbjct: 505 GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564
Query: 611 KPVLPSGSTSPSPLPFLHGSLSTGTP----------QPQPPSESTEKEPE---------- 650
KP+ P + + P G T P P+ + +T E +
Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624
Query: 651 ----------------QDGPAAPADGSTVESLPRP---LSPTKLTPIV--HSPLRYQSDA 689
Q A D + V S P+P +P T V SP Q+
Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP 684
Query: 690 DLEAL-RRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPS-P 747
+A ++ L+ AP P K + +P G P+ + ++L+ + P +PS P
Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS---KPAPPKEPSVP 741
Query: 748 SQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPE-PEELIC 806
S+ +AD +P P +P ++ + P+ P +
Sbjct: 742 SEQDKAPVAD-----------------DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 807 PQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPA---SHPPATS 863
Q +T P + + + ++ P P E SP + + P P + SHP +S
Sbjct: 785 SQAEEKTTPPLKTD-----SAKPSQSFP-PTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 864 TNK 866
+K
Sbjct: 839 ESK 841
Score = 52.0 bits (123), Expect = 3e-06
Identities = 92/392 (23%), Positives = 129/392 (32%), Gaps = 91/392 (23%)
Query: 489 RPSAGLPSRQRPTLLPAT-GSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPEL 547
+P +P +Q P P TP+ SSQQ ++ S PP P GP P D +L
Sbjct: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA-KL 272
Query: 548 PLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKA 607
PL SRPQ+ K V S+
Sbjct: 273 PLQ--------RDASRPQT--KQADIVRGESV---------------------------- 294
Query: 608 VYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLP 667
KP LPS S P P TP +PP++ E Q GPA P + + P
Sbjct: 295 ---KPSLPSPSKPPIQQP---------TPG-KPPAQQPGHEKSQPGPAKPPAQPSGLTKP 341
Query: 668 RPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLY 727
P + P V P + A + L A P ++ S GP K L
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPA------QPLGPAKPPAQQTGSEKPSSEQPGP---KALA 392
Query: 728 QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAP 787
Q G+ TP QP P A +++ +P A P +P
Sbjct: 393 Q-----PPGVGKTPAQQPGP-----------------AKPPTQQVGTPKPLAQQPGLQSP 430
Query: 788 SSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQ 847
+ + P +P P Q A P + + Q+P P P +Q
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPA---QQAGPGKTSAQQTGPTKPPSQLPGPAKPPP----QQ 483
Query: 848 VPPAPLPPASHPPATSTNKRTNLKKPNSERTG 879
PA PP A +++ KP ++ G
Sbjct: 484 PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG 515
Score = 50.8 bits (120), Expect = 7e-06
Identities = 89/416 (21%), Positives = 146/416 (35%), Gaps = 60/416 (14%)
Query: 466 PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA-TGSTPQPGSSQQIQQRISV 524
P P P ++ ++ P P P ++PTL + + QP + + +
Sbjct: 677 PQPQQTSPKKDAA-PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK--PA 733
Query: 525 PPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYL 584
PP P+ P D KP+ P V L S P + SS + S
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP-----DIPSSKVQSQAE 788
Query: 585 QQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSES 644
++ TPP +K KP T PF ++ P+P S+S
Sbjct: 789 EKTTPP--------------LKTDSAKPSQSFPPTGEKVSPFDSKAI------PRPASDS 828
Query: 645 TEKEPEQDGPAAPADGST-VESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPR 703
K GP++ + G V+ + + P K + + + DA PR
Sbjct: 829 --KIISHPGPSSESKGQKQVDPVQKKEEPKK----AQTKMSPKPDAKPMPKGSPTPPGPR 882
Query: 704 PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQD-----FMGTLADV 758
P ++ T + P P Q +RF+ G + P QP+ Q+ G A +
Sbjct: 883 PTAGQTVPTPQQSPK-PQEQS---RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI 938
Query: 759 DNGNTNANGNLEELPPAQPTAP-LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPA 817
+ +N + P + P P + AP+ PS P P++T Q A PA
Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAPA--------PSQPPTSQGPPKSTGQ-APPA 989
Query: 818 EDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873
++P ++ +P AE P EQ P P + ++ +P
Sbjct: 990 P-----AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040
Score = 50.1 bits (118), Expect = 1e-05
Identities = 95/457 (20%), Positives = 155/457 (33%), Gaps = 83/457 (18%)
Query: 396 SSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG 455
S SS +P Q + KD + + + + +P P K PP +
Sbjct: 673 SKSSPQPQQTSPK--KDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS 730
Query: 456 KQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSS 515
K PP + PS P + ++ K+ + +P+ L S T P P
Sbjct: 731 KPAPPKEPSVPSEQDKAPVAD---DKPKQPKMVKPTTDLVSSSSATTKP---DIPSSKVQ 784
Query: 516 QQIQQRISVP-------PSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPR 568
Q +++ + P PS ++PP G P DSK +P + ++ G P S
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF-DSKA-IPRPASDSKIISHPG--PSSES 840
Query: 569 KGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLH 628
KG + V+ +Q+ PK Q K KP+ T P P P
Sbjct: 841 KGQKQVDP-------VQKKEEPKKAQ-------TKMSPKPDAKPMPKGSPTPPGPRPTAG 886
Query: 629 GSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSD 688
++ T P+P +S L I +P + Q
Sbjct: 887 QTVPTPQQSPKPQEQSRR------------------------FSLNLGSITDAP-KSQPT 921
Query: 689 ADLEALRRKLANAPRPL-KKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQ-PS 746
E + KL + + S++ G GP+ Q G P Q P+
Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ------------SGPGAPMKQAPA 969
Query: 747 PSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELIC 806
PSQ G + G + PPA P +P + + A + P E +
Sbjct: 970 PSQ------PPTSQGPPKSTG---QAPPA-PAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
Query: 807 PQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSP 843
T + P +D+ + A P +P+ + ++P P
Sbjct: 1020 RTETEKKPPPIKDSKSLTAE-PQKAVLPTKLEKSPKP 1055
Score = 39.3 bits (90), Expect = 0.020
Identities = 56/231 (24%), Positives = 81/231 (35%), Gaps = 43/231 (18%)
Query: 495 PSRQRPTLLPATGSTP---QPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551
P+ Q P+ P+ S P +P + PP P PP PP P P LP
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 552 AIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVY-- 609
+ +P + K L A+P P + AV
Sbjct: 2432 SPKPTILPKKK---------------------LTVASPVTTATPLFDAVTTLETTAVLRS 2470
Query: 610 -GKPVLPSGSTSPSPLPFLHGSLSTG---TPQPQPPSESTEKEPEQDGPAAPADGSTVES 665
G PV +T+P P+P S+ +G T +P+P K P P P +T +
Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEP-----SKPPIAPKPVIPQLPTTTQK 2525
Query: 666 LPRPL--SPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEP 714
P + PT L+ L + AD KL + PL S+ + P
Sbjct: 2526 -PTDIHPKPTGLSLTSSMTLNLVTSADY-----KLPSPTSPLSPHSNKSSP 2570
Score = 38.5 bits (88), Expect = 0.035
Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 18/133 (13%)
Query: 137 RQQQQIENQQQMLVA---KEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKI 193
+QQQQ++ ++++L K+QR + ER++ Q E EK+ K KL+++
Sbjct: 3209 KQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQK--------KLEEL 3260
Query: 194 RAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQL-EDLKKGKLNG 252
++M+ + + + E + M QE + Q + ++ QL QQL + L++ K+
Sbjct: 3261 QSMKQHLLFQQ------EEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314
Query: 253 FQSYNGKLTGPAA 265
YN +G A+
Sbjct: 3315 IYQYNYDPSGTAS 3327
Score = 32.7 bits (73), Expect = 1.9
Identities = 35/156 (22%), Positives = 51/156 (32%), Gaps = 17/156 (10%)
Query: 773 PPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQ 832
PP P P P P P + P+ P++ + + TA P D + T
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRS 2470
Query: 833 IPSPVAEAPSPGEEQVPPAP-----------LPPASHPPATSTNKRTNLKKPNSERTGHG 881
PV + VPP P P S PP L + T
Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD-- 2528
Query: 882 LRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKP 917
+ P L L +S+ +LV Y++ P+ P
Sbjct: 2529 --IHPKPTGLSLTSSM--TLNLVTSADYKLPSPTSP 2560
Score = 32.0 bits (71), Expect = 3.3
Identities = 28/104 (26%), Positives = 34/104 (32%), Gaps = 3/104 (2%)
Query: 773 PPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEP---AEDNNNNVATVPT 829
PP P P P P P P P+ I P+ A P A + V T+ T
Sbjct: 2405 PPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET 2464
Query: 830 TEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKP 873
T + S PP P P+S P R KP
Sbjct: 2465 TAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKP 2508
Score = 31.2 bits (69), Expect = 5.6
Identities = 56/226 (24%), Positives = 81/226 (35%), Gaps = 31/226 (13%)
Query: 417 GSVKQGTVSSQPVPF---SALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGP 473
GS ++ ++P PF S+L + +P PPP P PP P P P P
Sbjct: 2379 GSPSVSSLPAKPRPFFRSSSLDISAQP-----PPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA 533
T +++ + P +A P T L T G RI P PP
Sbjct: 2434 KPTILPKKKLTVASPVTTA-TPLFDAVTTLETTAVLRSNGLP---VTRICTTAPPPVPPK 2489
Query: 534 GPPAFPAG-----DSKPELPLTVAIRPFLADKGSRPQSPRK-GPQTVNSSSIYSMYLQQA 587
P + P+G +P P +A +P + + Q P P+ S SM L
Sbjct: 2490 -PSSIPSGLVFTHRPEPSKP-PIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV 2547
Query: 588 TPPKNYQPAAHSAL-----------NKSVKAVYGKPVLPSGSTSPS 622
T P+ S L +KS+ Y LPS +P+
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPT 2593
Score = 30.4 bits (67), Expect = 9.5
Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 6/74 (8%)
Query: 794 NELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPL 853
++LPS P P A+P ++ + P P P P PP PL
Sbjct: 2374 SQLPSGSPSVSSLP------AKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427
Query: 854 PPASHPPATSTNKR 867
PP + P T K+
Sbjct: 2428 PPPTSPKPTILPKK 2441
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 70.9 bits (172), Expect = 6e-12
Identities = 42/120 (35%), Positives = 64/120 (53%), Gaps = 3/120 (2%)
Query: 889 LALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVN 948
L L D++ + + VQ+++ + DP +D+G T LH A C G+ IV+ LLD G + N
Sbjct: 111 LKRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPN 170
Query: 949 AADSDGWTPLHCAASCNSVHLCKQLVESGAAIFA---STISDIETAADKCEEMEEGYIQC 1005
D G TPLH AA N V + L+ GA + A + + + A K ++EG+ QC
Sbjct: 171 QRDGLGNTPLHLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHAQC 230
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 68.9 bits (167), Expect = 2e-11
Identities = 112/462 (24%), Positives = 169/462 (36%), Gaps = 62/462 (13%)
Query: 435 GPTEKPGIEIGKVPP---PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPS 491
G ++P G+ P I G+ P + T + + S+ + ++E S P S
Sbjct: 33 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 92
Query: 492 AGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551
RQR + T + S + Q IS P SP+ + DS+ +
Sbjct: 93 N---KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEG-----ESSDSR-SVNDEG 143
Query: 552 AIRPFLADKGSRPQSPR-KGPQTVNSSSIYSMYLQ--QATPPKNYQPAAHSALNKSVKAV 608
+ P D+ +R SP PQ S S S Q QA PP P + S A
Sbjct: 144 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS--AP 201
Query: 609 YGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPR 668
G P LP+ P P P S + PQ P + +P+ P AP + ++ P
Sbjct: 202 PGTPQLPT----PGPTP----SATAVPPQGSPTASQAPNQPQ--APTAPVPHTHIQQAPA 251
Query: 669 PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQK---L 725
L P + P H P L+ L P + + +GP GP+ + L
Sbjct: 252 -LHPQR-PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL-HGQGPPGPHSLQAGPL 308
Query: 726 LY-----QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNL----EELPPAQ 776
L Q F +G SP+ + T + + + LPPA
Sbjct: 309 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 368
Query: 777 ---------PTAPLPAEPAPSSDANDNELPSPEPEEL---------ICPQTTHQTAEPAE 818
PT P+P PAP + + L P P + + P ++ T P
Sbjct: 369 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428
Query: 819 DNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPP 860
+ + +P ++ +PS A+ P G Q P PPASHPP
Sbjct: 429 AHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPP 468
Score = 52.0 bits (123), Expect = 3e-06
Identities = 110/448 (24%), Positives = 146/448 (32%), Gaps = 55/448 (12%)
Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449
P+ + N S S Q + P+++ S P + PT P VPP
Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 221
Query: 450 PIPGVGKQLP--PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507
Q P P T P P + + +R P P PS P L P TG
Sbjct: 222 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH---PS-PHPPLQPLTG 277
Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSP 567
S QP + Q PP P GP + AG P L G PQ
Sbjct: 278 SAGQPSAPSHAQ-----PPLHGQGPPGPHSLQAG-------------PLLQHPGP-PQPF 318
Query: 568 RKGPQTVNSSSIYSMYLQQATPPKNYQ-PAAHSALNKSVKAVYGKPVLPSGSTSPSPLPF 626
PQ + A P + Q PA+ SAL +S + +P+ P+PL
Sbjct: 319 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPREQPL------PPAPLAM 371
Query: 627 LHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRP--LSPTKLTPIVHSPLR 684
H TP PQ P+ K P + P+ S +LP P L P H P
Sbjct: 372 PHIKPPPTTPIPQLPAPQAHKHPPH--LSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 429
Query: 685 YQSDADLEALRRKLANAPRP---LKKRSSITEPEGPGGPN------IQKLLYQRFNTLAG 735
+ L + L ++P L + ++ P P Q Q G
Sbjct: 430 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 489
Query: 736 GMEGTPFYQPSPSQDFMGTLADVD--------NGNTNANGNLEELPPAQ-PTAPLPAEPA 786
TP PS S G +G + A G+ LP Q L
Sbjct: 490 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 549
Query: 787 PSSDANDNELPSPEPEELICPQTTHQTA 814
P S PSPEP + P Q+A
Sbjct: 550 PESPPPPPRSPSPEPTVVDTPSHASQSA 577
Score = 38.9 bits (89), Expect = 0.027
Identities = 62/230 (26%), Positives = 81/230 (35%), Gaps = 44/230 (19%)
Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390
S Q+PL TS A +Q+P++ S P + Q L A A P
Sbjct: 325 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM------------P 372
Query: 391 TLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVP-----FSALGPTEKPGIEIG 445
+K ++ + + A P + G ++ P P S+L P
Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-- 430
Query: 446 KVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA 505
PPP+ QL P PS PG T S +LP P A P PT L
Sbjct: 431 --PPPL-----QLMPQSQPLPSSPAQPPGLTQSQ------NLPPPPASHP----PTGLHQ 473
Query: 506 TGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP 555
PQP Q VP P PP PP P+ + P P T A P
Sbjct: 474 VA--PQP----PFAQHPFVPGGP--PPITPPTCPSTSTPPAGPGTSAQPP 515
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 68.9 bits (167), Expect = 2e-11
Identities = 112/462 (24%), Positives = 169/462 (36%), Gaps = 62/462 (13%)
Query: 435 GPTEKPGIEIGKVPP---PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPS 491
G ++P G+ P I G+ P + T + + S+ + ++E S P S
Sbjct: 587 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 646
Query: 492 AGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551
RQR + T + S + Q IS P SP+ + DS+ +
Sbjct: 647 N---KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEG-----ESSDSR-SVNDEG 697
Query: 552 AIRPFLADKGSRPQSPR-KGPQTVNSSSIYSMYLQ--QATPPKNYQPAAHSALNKSVKAV 608
+ P D+ +R SP PQ S S S Q QA PP P + S A
Sbjct: 698 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS--AP 755
Query: 609 YGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPR 668
G P LP+ P P P S + PQ P + +P+ P AP + ++ P
Sbjct: 756 PGTPQLPT----PGPTP----SATAVPPQGSPTASQAPNQPQ--APTAPVPHTHIQQAPA 805
Query: 669 PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQK---L 725
L P + P H P L+ L P + + +GP GP+ + L
Sbjct: 806 -LHPQR-PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL-HGQGPPGPHSLQAGPL 862
Query: 726 LY-----QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNL----EELPPAQ 776
L Q F +G SP+ + T + + + LPPA
Sbjct: 863 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922
Query: 777 ---------PTAPLPAEPAPSSDANDNELPSPEPEEL---------ICPQTTHQTAEPAE 818
PT P+P PAP + + L P P + + P ++ T P
Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 819 DNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPP 860
+ + +P ++ +PS A+ P G Q P PPASHPP
Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPP 1022
Score = 52.0 bits (123), Expect = 3e-06
Identities = 110/448 (24%), Positives = 146/448 (32%), Gaps = 55/448 (12%)
Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449
P+ + N S S Q + P+++ S P + PT P VPP
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 775
Query: 450 PIPGVGKQLP--PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507
Q P P T P P + + +R P P PS P L P TG
Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH---PS-PHPPLQPLTG 831
Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSP 567
S QP + Q PP P GP + AG P L G PQ
Sbjct: 832 SAGQPSAPSHAQ-----PPLHGQGPPGPHSLQAG-------------PLLQHPGP-PQPF 872
Query: 568 RKGPQTVNSSSIYSMYLQQATPPKNYQ-PAAHSALNKSVKAVYGKPVLPSGSTSPSPLPF 626
PQ + A P + Q PA+ SAL +S + +P+ P+PL
Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPREQPL------PPAPLAM 925
Query: 627 LHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRP--LSPTKLTPIVHSPLR 684
H TP PQ P+ K P + P+ S +LP P L P H P
Sbjct: 926 PHIKPPPTTPIPQLPAPQAHKHPPH--LSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983
Query: 685 YQSDADLEALRRKLANAPRP---LKKRSSITEPEGPGGPN------IQKLLYQRFNTLAG 735
+ L + L ++P L + ++ P P Q Q G
Sbjct: 984 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Query: 736 GMEGTPFYQPSPSQDFMGTLADVD--------NGNTNANGNLEELPPAQ-PTAPLPAEPA 786
TP PS S G +G + A G+ LP Q L
Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 1103
Query: 787 PSSDANDNELPSPEPEELICPQTTHQTA 814
P S PSPEP + P Q+A
Sbjct: 1104 PESPPPPPRSPSPEPTVVDTPSHASQSA 1131
Score = 38.9 bits (89), Expect = 0.027
Identities = 62/230 (26%), Positives = 81/230 (35%), Gaps = 44/230 (19%)
Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390
S Q+PL TS A +Q+P++ S P + Q L A A P
Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM------------P 926
Query: 391 TLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVP-----FSALGPTEKPGIEIG 445
+K ++ + + A P + G ++ P P S+L P
Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-- 984
Query: 446 KVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA 505
PPP+ QL P PS PG T S +LP P A P PT L
Sbjct: 985 --PPPL-----QLMPQSQPLPSSPAQPPGLTQSQ------NLPPPPASHP----PTGLHQ 1027
Query: 506 TGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP 555
PQP Q VP P PP PP P+ + P P T A P
Sbjct: 1028 VA--PQP----PFAQHPFVPGGP--PPITPPTCPSTSTPPAGPGTSAQPP 1069
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 68.9 bits (167), Expect = 2e-11
Identities = 112/462 (24%), Positives = 169/462 (36%), Gaps = 62/462 (13%)
Query: 435 GPTEKPGIEIGKVPP---PIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPS 491
G ++P G+ P I G+ P + T + + S+ + ++E S P S
Sbjct: 587 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 646
Query: 492 AGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTV 551
RQR + T + S + Q IS P SP+ + DS+ +
Sbjct: 647 N---KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEG-----ESSDSR-SVNDEG 697
Query: 552 AIRPFLADKGSRPQSPR-KGPQTVNSSSIYSMYLQ--QATPPKNYQPAAHSALNKSVKAV 608
+ P D+ +R SP PQ S S S Q QA PP P + S A
Sbjct: 698 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS--AP 755
Query: 609 YGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPR 668
G P LP+ P P P S + PQ P + +P+ P AP + ++ P
Sbjct: 756 PGTPQLPT----PGPTP----SATAVPPQGSPTASQAPNQPQ--APTAPVPHTHIQQAPA 805
Query: 669 PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQK---L 725
L P + P H P L+ L P + + +GP GP+ + L
Sbjct: 806 -LHPQR-PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL-HGQGPPGPHSLQAGPL 862
Query: 726 LY-----QRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNL----EELPPAQ 776
L Q F +G SP+ + T + + + LPPA
Sbjct: 863 LQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922
Query: 777 ---------PTAPLPAEPAPSSDANDNELPSPEPEEL---------ICPQTTHQTAEPAE 818
PT P+P PAP + + L P P + + P ++ T P
Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 819 DNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPP 860
+ + +P ++ +PS A+ P G Q P PPASHPP
Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPASHPP 1022
Score = 52.0 bits (123), Expect = 3e-06
Identities = 110/448 (24%), Positives = 146/448 (32%), Gaps = 55/448 (12%)
Query: 390 PTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPP 449
P+ + N S S Q + P+++ S P + PT P VPP
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPP 775
Query: 450 PIPGVGKQLP--PSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATG 507
Q P P T P P + + +R P P PS P L P TG
Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH---PS-PHPPLQPLTG 831
Query: 508 STPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSP 567
S QP + Q PP P GP + AG P L G PQ
Sbjct: 832 SAGQPSAPSHAQ-----PPLHGQGPPGPHSLQAG-------------PLLQHPGP-PQPF 872
Query: 568 RKGPQTVNSSSIYSMYLQQATPPKNYQ-PAAHSALNKSVKAVYGKPVLPSGSTSPSPLPF 626
PQ + A P + Q PA+ SAL +S + +P+ P+PL
Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSAL-QSQQPPREQPL------PPAPLAM 925
Query: 627 LHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRP--LSPTKLTPIVHSPLR 684
H TP PQ P+ K P + P+ S +LP P L P H P
Sbjct: 926 PHIKPPPTTPIPQLPAPQAHKHPPH--LSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983
Query: 685 YQSDADLEALRRKLANAPRP---LKKRSSITEPEGPGGPN------IQKLLYQRFNTLAG 735
+ L + L ++P L + ++ P P Q Q G
Sbjct: 984 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043
Query: 736 GMEGTPFYQPSPSQDFMGTLADVD--------NGNTNANGNLEELPPAQ-PTAPLPAEPA 786
TP PS S G +G + A G+ LP Q L
Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 1103
Query: 787 PSSDANDNELPSPEPEELICPQTTHQTA 814
P S PSPEP + P Q+A
Sbjct: 1104 PESPPPPPRSPSPEPTVVDTPSHASQSA 1131
Score = 38.9 bits (89), Expect = 0.027
Identities = 62/230 (26%), Positives = 81/230 (35%), Gaps = 44/230 (19%)
Query: 331 SSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWP 390
S Q+PL TS A +Q+P++ S P + Q L A A P
Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM------------P 926
Query: 391 TLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVP-----FSALGPTEKPGIEIG 445
+K ++ + + A P + G ++ P P S+L P
Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH-- 984
Query: 446 KVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPA 505
PPP+ QL P PS PG T S +LP P A P PT L
Sbjct: 985 --PPPL-----QLMPQSQPLPSSPAQPPGLTQSQ------NLPPPPASHP----PTGLHQ 1027
Query: 506 TGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRP 555
PQP Q VP P PP PP P+ + P P T A P
Sbjct: 1028 VA--PQP----PFAQHPFVPGGP--PPITPPTCPSTSTPPAGPGTSAQPP 1069
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 68.6 bits (166), Expect = 3e-11
Identities = 120/528 (22%), Positives = 207/528 (39%), Gaps = 81/528 (15%)
Query: 81 RHEDSPTENSEQGGRQTQEQRTQR----NVINVPGEKRTENGVGNPRVELTLSELQDMAA 136
R E TE G + + + +++NVPGE + E ++ A
Sbjct: 313 RGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQE---NKSNSEAL 369
Query: 137 RQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAM 196
+QQQQ++ QQQ + H L Q++RR ++ E ++++ ++R E ++ KL++
Sbjct: 370 KQQQQLQQQQQRDPEAHIK-HLLHQRQRRIEEQKEERRRVEE-QQRREREQRKLQEKEQQ 427
Query: 197 RGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSY 256
R D L E ER A E++QE + L + S++L+
Sbjct: 428 RRLEDMQA-----LRREEERRQA---EREQEYKRKQLEEQRQSERLQR------------ 467
Query: 257 NGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRER 316
+L++ + L+ Q Q+Q + QQQ++LL + + ++ +
Sbjct: 468 ----------QLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKP 517
Query: 317 LYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSA--------GSFPVLGDPIKPQ 368
+ ++++ R SPL+ S + + GP +P A P + P++PQ
Sbjct: 518 AWAREVE-ERTRMNKQQNSPLAKS-KPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQ 575
Query: 369 SLSIASNAAH-----------GRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEG 417
S AH RS+S D L +S P A PS G
Sbjct: 576 EGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASH-DPDPAIPAPTATPSARG 634
Query: 418 SV-KQGTVSSQPVPFSALGPTEKPGIEI---GKVPPPIPGVGKQLPPSYGTYPSPTPLGP 473
+V +Q + + P GP+ P + + PP +P Q S T + + G
Sbjct: 635 AVIRQNSDPTSEGP----GPSPNPPAWVRPDNEAPPKVP----QRTSSIATALNTSGAGG 686
Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQRPTLLPAT-GSTPQPGSSQQIQQRISVPP--SPTY 530
+ R L R G + ++LPA+ G PQ GS ++ + +S P SP
Sbjct: 687 SRPAQAVRASNPDLRRSDPGW--ERSDSVLPASHGHLPQAGSLERNRVGVSSKPDSSPVL 744
Query: 531 PPAGPPAFPAGDSKPELPLT-VAIRPFLADKGSRPQSPRKGPQTVNSS 577
P S+P P V ++ D+ RP P+K +SS
Sbjct: 745 SPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRP--PKKAMDYSSSS 790
Score = 34.3 bits (77), Expect = 0.66
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 9/117 (7%)
Query: 60 HMMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGV 119
H++++ ++ ++EE + R E+ EQ R+ QE+ QR + ++ +R E
Sbjct: 389 HLLHQRQRRIEEQKEERR---RVEEQQRREREQ--RKLQEKEQQRRLEDMQALRREEERR 443
Query: 120 GNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKL 176
R + E + +Q+Q E Q+ L + L L+QQ+++QQ + ++L
Sbjct: 444 QAEREQ----EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQL 496
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 67.8 bits (164), Expect = 5e-11
Identities = 113/470 (24%), Positives = 154/470 (32%), Gaps = 88/470 (18%)
Query: 308 KRISELRERLYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKP 367
+R++ LR L + +SS +P SG P I P F + P P
Sbjct: 614 ERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSG------PQILTPLGDRFVIPPHPKVP 667
Query: 368 QSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQ 427
S P K S + P A A P S + S
Sbjct: 668 APFSP-----------------PPSKPRSPNPAAPALAAPAVVPGPV---STTDASPQSP 707
Query: 428 PVPFSALGPT-EKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPL------GPGSTSSLE 480
P P + L P E P I + PPP P PPSY P PT P ++ + E
Sbjct: 708 PTPQTTLTPLQESPVISKDQSPPPSP------PPSYHPPPPPTKKPEVVVEAPSASETAE 761
Query: 481 RR-KEGSLPRPSAGLPSRQR-----------------------PTLLPATGSTPQPGSSQ 516
++ + P P P Q P+ P S+P SS
Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSS 821
Query: 517 QIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNS 576
+I P SP PPA P PA + + P KG P G V
Sbjct: 822 ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTP 881
Query: 577 SSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLP----------- 625
S + + L+ P A AL S + L SG SP P P
Sbjct: 882 SLLQMVRLRSVGAPGG---APTPALGPSAPQKPLRRAL-SGRASPVPAPSSGLHAAVRLK 937
Query: 626 --FLHGSLSTGTPQPQPPSESTEKEPEQDGPAAP---ADGSTVESLPRPLSP---TKLTP 677
L S + QP P E+ + P+ A + GS L RP+SP L
Sbjct: 938 ACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQR 997
Query: 678 IVHSPLRYQSDADLEALRRKLANAPRPLKKRSS--ITEPEGPGGPNIQKL 725
+ + LR S+ +K AP P+ ++ S + P P P + L
Sbjct: 998 NLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPL 1047
Score = 63.2 bits (152), Expect = 1e-09
Identities = 128/556 (23%), Positives = 193/556 (34%), Gaps = 86/556 (15%)
Query: 352 VPSAGSFPVLGDPIKPQSLSIASNA---AHGRSKSANDGNWPTLKQNSSSSVKPVQVAGA 408
V S G F + P +P+S +S++ +H +S + TL S +P +
Sbjct: 390 VRSLGRFSSVSSP-QPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTAS 448
Query: 409 DWKDPSVEGSVKQGTVS-------SQPVPFSALGPTEKPGIEIGKV--PPPIPGVGKQLP 459
+ P +G +G+ S S + + G + + K+ PPP P +
Sbjct: 449 NSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPP----RRT 504
Query: 460 PSYGTYPSPTPLGP-GSTSSLERRKEGSLPRP-----SAGLPSRQRPTLLPATGSTP--Q 511
S P GP G ER+++ LPRP S G + P PA P
Sbjct: 505 HSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPN-PANSWVPGLS 563
Query: 512 PGSSQQ---IQQRISVPPS--------PTYPP---AGPPAFPAGDSKPELPLTVAIRP-- 555
PG S++ +R P S PT PP AGPPA P P+ ++R
Sbjct: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPG 623
Query: 556 --------FLADKGSRPQ-SPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVK 606
L S P S R GPQ + + P + P + +
Sbjct: 624 ASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPA 683
Query: 607 AVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESL 666
A P L + + P P+ S + +PQ PP+ T P Q+ P D S S
Sbjct: 684 A----PALAAPAVVPGPV-----STTDASPQ-SPPTPQTTLTPLQESPVISKDQSPPPSP 733
Query: 667 PR----PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNI 722
P P PTK +V A+ P P + ++ + P
Sbjct: 734 PPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPP--- 790
Query: 723 QKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP-L 781
++ + + G G+P SP+ A L+ PP P P
Sbjct: 791 EEAFFSVASPEPAGPSGSPELVSSPAASSSSATA------------LQIQPPGSPDPPPA 838
Query: 782 PAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAP 841
P PAP+S A + P+ E + C + P ED + T + + AP
Sbjct: 839 PPAPAPASSAPGHVAKLPQKEPVGC---SKGGGPPREDVGAPLVTPSLLQMVRLRSVGAP 895
Query: 842 --SPGEEQVPPAPLPP 855
+P P AP P
Sbjct: 896 GGAPTPALGPSAPQKP 911
Score = 58.5 bits (140), Expect = 3e-08
Identities = 135/592 (22%), Positives = 202/592 (34%), Gaps = 96/592 (16%)
Query: 327 VNGTSSPQSPLSTSGRVAAVGPYIQ--VPSAGSFPVLGDPIKPQSLSIASNAAHGRSK-- 382
+ G + P PLS + ++ Y+ +P A VL + +L S R
Sbjct: 328 LTGGAGPAEPLSPAMSISPQATYLSKLIPHA----VLPPTVDVVALGRCSLRTLSRCSLH 383
Query: 383 SANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTE-KPG 441
SA+ + +L + SS S + + S T+ S S+ G +E +P
Sbjct: 384 SASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPE 443
Query: 442 IEIGK---VPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQ 498
VPPP G G+ P T + + +L R G L S L +
Sbjct: 444 SSTASNSVVPPPQGGSGRGSPSGGSTAEA--------SDTLSIRSSGQLSGRSVSLRKLK 495
Query: 499 RPTLLPATGSTPQPGSSQQIQQR-ISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIR--- 554
RP P P + + QR ++VP P G P P +P+LP
Sbjct: 496 RPP--------PPPRRTHSLHQRGLAVPDGPL----GLPPKPERKQQPQLPRPPTTGGSE 543
Query: 555 ----------------PFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQAT-PPKNYQ-PA 596
P L+ GSR + PR +T++ SS YS T PPK P
Sbjct: 544 GAGAAPCPPNPANSWVPGLSPGGSR-RPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP 602
Query: 597 AHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQ----PQPPSESTEKEPEQD 652
A + K + G++ S L L S S P PQ + ++
Sbjct: 603 ASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPP 662
Query: 653 GPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSIT 712
P PA S S PR SP P + +P A P P+ +
Sbjct: 663 HPKVPAPFSPPPSKPR--SPNPAAPALAAP----------------AVVPGPVSTTDA-- 702
Query: 713 EPEGPGGPNIQKLLYQRFNTLAGGMEGTP-----FYQPSPSQDFMGTLADVDNGNTNANG 767
P+ P P Q ++ P ++ P P + + + + A
Sbjct: 703 SPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETA-- 760
Query: 768 NLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATV 827
E P P P P PAP + + + P PEE + + A P+ + + +
Sbjct: 761 ---EEPLQDPNWPPPPPPAPE-EQDLSMADFPPPEEAFFSVASPEPAGPS--GSPELVSS 814
Query: 828 PTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTG 879
P + + PG PPAP PA PA+S K P E G
Sbjct: 815 PAASSSSATALQIQPPGSPDPPPAPPAPA---PASSAPGHV-AKLPQKEPVG 862
Score = 55.1 bits (131), Expect = 4e-07
Identities = 118/530 (22%), Positives = 174/530 (32%), Gaps = 91/530 (17%)
Query: 411 KDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPS--- 467
+ P+ GS G P P ++ P PG + PP P + L PS G Y S
Sbjct: 535 RPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGS--RRPPRSPE--RTLSPSSG-YSSQSG 589
Query: 468 -PT---------PLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQ 517
PT P PG + + SL P A + S ++ P S Q
Sbjct: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQ 649
Query: 518 IQ----QRISVPPSPTYP-PAGPPAFPAGDSKPELPLTVA---IRPFLADKGSRPQSPRK 569
I R +PP P P P PP P P A + ++ + PQSP
Sbjct: 650 ILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPT 709
Query: 570 GPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHG 629
T+ + + +PP + P+ H + K + T+ PL
Sbjct: 710 PQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ---- 765
Query: 630 SLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDA 689
P P PP+ + D P P + + P P P+ +V SP S A
Sbjct: 766 --DPNWPPPPPPAPEEQDLSMADFPP-PEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822
Query: 690 DLEALR--------------RKLANAPR-----PLKKRSSITEPEGP-----GGPNIQKL 725
++ ++AP P K+ ++ GP G P +
Sbjct: 823 TALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882
Query: 726 LYQRFNTLAGGMEG---TPFYQPSPSQD-----FMGTLADVDNGNTNANGNL-------- 769
L Q + G G TP PS Q G + V ++ + +
Sbjct: 883 LLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLA 942
Query: 770 --EELPPAQPTAPLPAEPAP--SSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVA 825
E L AQP P AEP P S + + + S +L + + E D N+
Sbjct: 943 ASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPV--SPETQADLQRNL- 999
Query: 826 TVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNS 875
VAE S E++ P AP PP + + P S
Sbjct: 1000 -----------VAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPAS 1038
Score = 43.1 bits (100), Expect = 0.001
Identities = 91/439 (20%), Positives = 146/439 (33%), Gaps = 74/439 (16%)
Query: 495 PSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIR 554
P RP L G T G ++ + +S+ P TY P P + + R
Sbjct: 315 PPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYL---SKLIPHAVLPPTVDVVALGR 371
Query: 555 PFLADKGSRPQSPRKGPQTVNS----SSIYSMYLQQATPPKNYQPAAHSALNKSV----- 605
L SR P +V S SS+ S + P + +HS + ++
Sbjct: 372 CSLRTL-SRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGS 430
Query: 606 --KAVYGKPVLPSGST-SPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGST 662
+ G P ST S S +P G G+P +E+++ + +
Sbjct: 431 TLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVS 490
Query: 663 VESLPRPLSPTKLTPIVHSPLRYQSDADL----EALRRKLANAPR--------------- 703
+ L RP P + T +H D L + R++ PR
Sbjct: 491 LRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPC 550
Query: 704 PLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGG---MEGTPFYQPS-------------- 746
P +S PGG +R + + G GTP P
Sbjct: 551 PPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQP 610
Query: 747 PSQDFMGTL----ADVDNGNTNANGNLEELPPAQPTAPL--------------PAEPAP- 787
P + + +L A V + T+ + + P+ + P P PAP
Sbjct: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF 670
Query: 788 SSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQ 847
S + P+P L P P + + + PT + +P+ E+P ++Q
Sbjct: 671 SPPPSKPRSPNPAAPALAAPAV---VPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQ 727
Query: 848 VPPAPLPPASHPPATSTNK 866
PP PP+ HPP T K
Sbjct: 728 SPPPSPPPSYHPPPPPTKK 746
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 67.0 bits (162), Expect = 9e-11
Identities = 87/386 (22%), Positives = 132/386 (34%), Gaps = 54/386 (13%)
Query: 490 PSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPL 549
P+ + + + P STP+ +S + P PT P A P PE P
Sbjct: 977 PATTVHAPEEPDTAAVRVSTPEEPASPAAA--VPTPEEPTSPAAAVPT-------PEEPT 1027
Query: 550 TVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVY 609
+ A ++ + P + P+ S + ++ T P P + + A
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA--AAV 1085
Query: 610 GKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRP 669
P P+ + P P S + P P+ P+ P + PA+PA ++P P
Sbjct: 1086 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPA-----AAVPTP 1140
Query: 670 LSPTKLTPIVHSPLRYQSDADL----EALRRKLANAPRPLKKRS------SITEPEGPGG 719
P P V +P S A E A P P + S ++ EP P
Sbjct: 1141 EEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAA 1200
Query: 720 PNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTA 779
TP + ++F A V A+ P +PT+
Sbjct: 1201 S-----------------VPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS 1243
Query: 780 PLPAEPAPSSDANDNELPSPEPEELICPQ----TTHQTAEPA------EDNNNNVATVPT 829
P A P + + PEEL P T + A PA E+ + A VPT
Sbjct: 1244 PAAAVPT-LEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPT 1302
Query: 830 TEQIPSPVAEAPSPGEEQVPPAPLPP 855
E P A P+P +P A +PP
Sbjct: 1303 PEVAAIPAASVPTPEVPAIPAAAVPP 1328
Score = 60.8 bits (146), Expect = 7e-09
Identities = 78/346 (22%), Positives = 119/346 (34%), Gaps = 41/346 (11%)
Query: 532 PAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPK 591
P GP PE P T A+R ++ + P + P+ S + ++ T P
Sbjct: 971 PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030
Query: 592 NYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQ 651
P + + A P P+ + P P S + P P+ P+ P
Sbjct: 1031 AAVPPPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
Query: 652 DGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSI 711
+ P +PA ++P P PT V +P S A + P +++
Sbjct: 1089 EEPTSPA-----AAVPTPEEPTSPAAAVPTPEEPASPA------AAVPTPEEPASPAAAV 1137
Query: 712 TEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSP---------SQDFMGTLADVDNGN 762
PE P P + + A + TP SP S F +A ++
Sbjct: 1138 PTPEEPAFPAPAVPTPEESASAAVAVP-TPEESASPAAAVPTPAESASFAAVVATLEEPT 1196
Query: 763 TNANG---------NLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQT 813
+ A LEE + P EPA + A N PEE P T
Sbjct: 1197 SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSN------PEEPTSPAAAVPT 1250
Query: 814 AEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHP 859
E + ++ A V T E++ SP A P+P E P A + P
Sbjct: 1251 LE---EPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEP 1293
Score = 50.1 bits (118), Expect = 1e-05
Identities = 82/349 (23%), Positives = 115/349 (32%), Gaps = 57/349 (16%)
Query: 520 QRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSI 579
+R +VP P G A A S E VA + +G + P+ +
Sbjct: 905 ERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAA--ITQEGMSAVAGFS-PEWAALAIT 961
Query: 580 YSMYLQQATPPKNYQPAA--HSALNKSVKAV-YGKPVLPSGSTSPSPLPFLHGSLSTGTP 636
+ + TP PA H+ AV P P+ + P P S + P
Sbjct: 962 VPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVP 1021
Query: 637 QPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRR 696
P+ P+ P + P +PA ++P P PT V +P S A
Sbjct: 1022 TPEEPTSPAAAVPPPEEPTSPA-----AAVPTPEEPTSPAAAVPTPEEPTSPA------A 1070
Query: 697 KLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLA 756
+ P +++ PE P P TP SP+
Sbjct: 1071 AVPTPEEPTSPAAAVPTPEEPTSP--------------AAAVPTPEEPTSPAA------- 1109
Query: 757 DVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEP 816
A EE PA P A +P P+S A P PEE P T E
Sbjct: 1110 --------AVPTPEE--PASPAAAVPTPEEPASPA----AAVPTPEEPAFPAPAVPTPE- 1154
Query: 817 AEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHP--PATS 863
++ + VPT E+ SP A P+P E A + P PA S
Sbjct: 1155 --ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAAS 1201
Score = 47.8 bits (112), Expect = 6e-05
Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 22/200 (11%)
Query: 669 PLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQ 728
P P VH+P + D A+R ++ P +++ PE P P +
Sbjct: 971 PEGPVTPATTVHAP----EEPDTAAVR--VSTPEEPASPAAAVPTPEEPTSPAAAVPTPE 1024
Query: 729 RFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPS 788
+ A + P ++ A V + P +PT+P A P P
Sbjct: 1025 EPTSPAAAVP--------PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1076
Query: 789 SDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQV 848
+ P PEE P T E + + A VPT E+ SP A P+P E
Sbjct: 1077 EPTSP-AAAVPTPEEPTSPAAAVPTPE---EPTSPAAAVPTPEEPASPAAAVPTPEEPAS 1132
Query: 849 P----PAPLPPASHPPATST 864
P P P PA PA T
Sbjct: 1133 PAAAVPTPEEPAFPAPAVPT 1152
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/259 (23%), Positives = 89/259 (34%), Gaps = 41/259 (15%)
Query: 611 KPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSES----TEKEPEQDGPAAPADGSTVESL 666
K V +G+T P L P Q PS + T K+ +P +G+++ ++
Sbjct: 812 KQVTKAGNTEPV--------LEEWIPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAV 863
Query: 667 PRPLSPT---KLTPIVHSPLRYQSDADLEA--LRRKLANAP-RPLKKRSSITEPEGPGGP 720
P P L P H + S LE + +AP R +++ PEG
Sbjct: 864 PAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAA- 922
Query: 721 NIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAP 780
++ E P + +Q+ M +A G E T P
Sbjct: 923 ---------VAAVSSPEETAPAVAAAITQEGMSAVA----------GFSPEWAALAITVP 963
Query: 781 LPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEA 840
+ E PEE P T E+ + A VPT E+ SP A
Sbjct: 964 ITEEDGTPEGPVTPATTVHAPEE---PDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
Query: 841 PSPGEEQVPPAPLPPASHP 859
P+P E P A +PP P
Sbjct: 1021 PTPEEPTSPAAAVPPPEEP 1039
>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
sapiens]
Length = 782
Score = 67.0 bits (162), Expect = 9e-11
Identities = 48/147 (32%), Positives = 72/147 (48%), Gaps = 19/147 (12%)
Query: 884 VRFNPLALLLDASLEGEFDLVQRIIYEVE-------DPSKP----------NDEGITPLH 926
VRF A L A G+ D + ++ + DP+ P N +GI+ LH
Sbjct: 47 VRFERAAEFLAACAGGDLDEARLMLRAADPGPGAELDPAAPPPARAVLDSTNADGISALH 106
Query: 927 NAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTIS 986
A + +V+FL++ G VN AD++GWTPLH AASC + + + L+ GA I A+ S
Sbjct: 107 QACIDENLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANI-AAVNS 165
Query: 987 DIETAADKCE-EMEEGYIQCSQFLYGV 1012
D + D E + EG ++ GV
Sbjct: 166 DGDLPLDLAESDAMEGLLKAEIARRGV 192
Score = 53.9 bits (128), Expect = 8e-07
Identities = 37/124 (29%), Positives = 59/124 (47%), Gaps = 20/124 (16%)
Query: 840 APSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEG 899
A PG P A L PA+ PPA + TN + ++ L A ++
Sbjct: 73 AADPG----PGAELDPAAPPPARAVLDSTNA----------------DGISALHQACIDE 112
Query: 900 EFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLH 959
++V+ ++ + ++ ++EG TPLH A G+ I ++LL G N+ A +SDG PL
Sbjct: 113 NLEVVRFLVEQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLD 172
Query: 960 CAAS 963
A S
Sbjct: 173 LAES 176
Score = 48.5 bits (114), Expect = 3e-05
Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 921 GITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAI 980
G + LH A G+ +++ LL G + D DGWTPLH AA C+ L E G +
Sbjct: 227 GASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGM 286
Query: 981 FASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKL 1016
+ T C+ +E + + L QE L
Sbjct: 287 DSLT----HAGQRPCDLADEEVLSLLEELARKQEDL 318
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 66.6 bits (161), Expect = 1e-10
Identities = 110/494 (22%), Positives = 195/494 (39%), Gaps = 81/494 (16%)
Query: 81 RHEDSPTENSEQGGRQTQEQRTQR----NVINVPGEKRTENGVGNPRVELTLSELQDMAA 136
R E TE G + + + +++NVPGE + E ++ A
Sbjct: 313 RGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQE---NKSNSEAL 369
Query: 137 RQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERVEAQENKLKKIRAM 196
+QQQQ++ QQQ + H L Q++RR ++ E ++++ ++R E ++ KL++
Sbjct: 370 KQQQQLQQQQQRDPEAHIK-HLLHQRQRRIEEQKEERRRVEE-QQRREREQRKLQEKEQQ 427
Query: 197 RGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLEDLKKGKLNGFQSY 256
R D L E ER A E++QE + L + S++L+
Sbjct: 428 RRLEDMQA-----LRREEERRQA---EREQEYKRKQLEEQRQSERLQR------------ 467
Query: 257 NGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRER 316
+L++ + L+ Q Q+Q + QQQ++LL + + ++ +
Sbjct: 468 ----------QLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKP 517
Query: 317 LYGKKIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSA--------GSFPVLGDPIKPQ 368
+ ++++ R SPL+ S + + GP +P A P + P++PQ
Sbjct: 518 AWAREVE-ERTRMNKQQNSPLAKS-KPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQ 575
Query: 369 SLSIASNAAH-----------GRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEG 417
S AH RS+S D L +S P A PS G
Sbjct: 576 EGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASH-DPDPAIPAPTATPSARG 634
Query: 418 SV-KQGTVSSQPVPFSALGPTEKPGIEI---GKVPPPIPGVGKQLPPSYGTYPSPTPLGP 473
+V +Q + + P GP+ P + + PP +P Q S T + + G
Sbjct: 635 AVIRQNSDPTSEGP----GPSPNPPAWVRPDNEAPPKVP----QRTSSIATALNTSGAGG 686
Query: 474 GSTSSLERRKEGSLPRPSAGLPSRQRPTLLPAT-GSTPQPGSSQQIQQRISVPPSPTYPP 532
+ R L R G + ++LPA+ G PQ GS ++ + +S + P
Sbjct: 687 SRPAQAVRASNPDLRRSDPGW--ERSDSVLPASHGHLPQAGSLERNRVGVS-----SKPD 739
Query: 533 AGPPAFPAGDSKPE 546
+ P P +KP+
Sbjct: 740 SSPVLSPGNKAKPD 753
Score = 34.3 bits (77), Expect = 0.66
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 9/117 (7%)
Query: 60 HMMYEHLQKWGPRREEVKFFLRHEDSPTENSEQGGRQTQEQRTQRNVINVPGEKRTENGV 119
H++++ ++ ++EE + R E+ EQ R+ QE+ QR + ++ +R E
Sbjct: 389 HLLHQRQRRIEEQKEERR---RVEEQQRREREQ--RKLQEKEQQRRLEDMQALRREEERR 443
Query: 120 GNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKL 176
R + E + +Q+Q E Q+ L + L L+QQ+++QQ + ++L
Sbjct: 444 QAEREQ----EYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQL 496
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,940,677
Number of Sequences: 37866
Number of extensions: 3225763
Number of successful extensions: 37526
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 651
Number of HSP's successfully gapped in prelim test: 2147
Number of HSP's that attempted gapping in prelim test: 17858
Number of HSP's gapped (non-prelim): 14129
length of query: 1090
length of database: 18,247,518
effective HSP length: 113
effective length of query: 977
effective length of database: 13,968,660
effective search space: 13647380820
effective search space used: 13647380820
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.