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Search of human proteins with 24797114
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24797114 calcium-binding tyrosine phosphorylation-regulated
protein isoform b [Homo sapiens]
(475 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24797114 calcium-binding tyrosine phosphorylation-regulated p... 922 0.0
gi|24797108 calcium-binding tyrosine phosphorylation-regulated p... 910 0.0
gi|24797118 calcium-binding tyrosine phosphorylation-regulated p... 317 2e-86
gi|24797116 calcium-binding tyrosine phosphorylation-regulated p... 316 3e-86
gi|24797112 calcium-binding tyrosine phosphorylation-regulated p... 316 3e-86
gi|24797110 calcium-binding tyrosine phosphorylation-regulated p... 169 4e-42
gi|91982772 mucin 17 [Homo sapiens] 59 1e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 48 2e-05
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 43 7e-04
gi|8394343 sperm autoantigenic protein 17 [Homo sapiens] 42 0.001
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ... 42 0.002
gi|19923559 EMSY protein [Homo sapiens] 40 0.005
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 40 0.006
gi|110349719 titin isoform N2-A [Homo sapiens] 39 0.010
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 39 0.010
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 39 0.010
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 39 0.010
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 39 0.010
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 39 0.010
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 39 0.010
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 39 0.010
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 39 0.010
gi|148613886 regulatory factor X domain containing 2 [Homo sapiens] 39 0.013
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 38 0.018
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 38 0.018
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 38 0.023
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 38 0.023
gi|11641239 hypothetical protein LOC53838 [Homo sapiens] 38 0.023
gi|37595548 phosphoinositol 3-phosphate-binding protein-3 [Homo ... 38 0.023
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 37 0.030
>gi|24797114 calcium-binding tyrosine phosphorylation-regulated
protein isoform b [Homo sapiens]
Length = 475
Score = 922 bits (2382), Expect = 0.0
Identities = 475/475 (100%), Positives = 475/475 (100%)
Query: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRVEKWSEGTTPQK 60
MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRVEKWSEGTTPQK
Sbjct: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRVEKWSEGTTPQK 60
Query: 61 KLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVG 120
KLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVG
Sbjct: 61 KLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVG 120
Query: 121 GLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDV 180
GLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDV
Sbjct: 121 GLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDV 180
Query: 181 ATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPST 240
ATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPST
Sbjct: 181 ATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPST 240
Query: 241 ASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVI 300
ASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVI
Sbjct: 241 ASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVI 300
Query: 301 PFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVY 360
PFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVY
Sbjct: 301 PFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVY 360
Query: 361 MEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGE 420
MEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGE
Sbjct: 361 MEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGE 420
Query: 421 NSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE 475
NSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE
Sbjct: 421 NSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE 475
>gi|24797108 calcium-binding tyrosine phosphorylation-regulated
protein isoform a [Homo sapiens]
Length = 493
Score = 910 bits (2353), Expect = 0.0
Identities = 475/493 (96%), Positives = 475/493 (96%), Gaps = 18/493 (3%)
Query: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYR------------ 48
MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYR
Sbjct: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRGNTTMDIKDLVK 60
Query: 49 ------VEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT 102
VEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT
Sbjct: 61 QFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT 120
Query: 103 QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML 162
QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML
Sbjct: 121 QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML 180
Query: 163 GKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTS 222
GKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTS
Sbjct: 181 GKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTS 240
Query: 223 VHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDV 282
VHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDV
Sbjct: 241 VHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDV 300
Query: 283 PVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSV 342
PVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSV
Sbjct: 301 PVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSV 360
Query: 343 ESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLE 402
ESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLE
Sbjct: 361 ESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLE 420
Query: 403 VEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLT 462
VEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLT
Sbjct: 421 VEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLT 480
Query: 463 APEIEPEGESTAE 475
APEIEPEGESTAE
Sbjct: 481 APEIEPEGESTAE 493
>gi|24797118 calcium-binding tyrosine phosphorylation-regulated
protein isoform e [Homo sapiens]
Length = 221
Score = 317 bits (812), Expect = 2e-86
Identities = 165/192 (85%), Positives = 166/192 (86%), Gaps = 18/192 (9%)
Query: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYR------------ 48
MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYR
Sbjct: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRGNTTMDIKDLVK 60
Query: 49 ------VEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT 102
VEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT
Sbjct: 61 QFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT 120
Query: 103 QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML 162
QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML
Sbjct: 121 QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML 180
Query: 163 GKVSSIHSDQSD 174
V+ S D
Sbjct: 181 EDVAKKSSGSGD 192
>gi|24797116 calcium-binding tyrosine phosphorylation-regulated
protein isoform c [Homo sapiens]
Length = 379
Score = 316 bits (809), Expect = 3e-86
Identities = 163/185 (88%), Positives = 164/185 (88%), Gaps = 18/185 (9%)
Query: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYR------------ 48
MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYR
Sbjct: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRGNTTMDIKDLVK 60
Query: 49 ------VEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT 102
VEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT
Sbjct: 61 QFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT 120
Query: 103 QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML 162
QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML
Sbjct: 121 QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML 180
Query: 163 GKVSS 167
+S
Sbjct: 181 AMATS 185
>gi|24797112 calcium-binding tyrosine phosphorylation-regulated
protein isoform c [Homo sapiens]
Length = 379
Score = 316 bits (809), Expect = 3e-86
Identities = 163/185 (88%), Positives = 164/185 (88%), Gaps = 18/185 (9%)
Query: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYR------------ 48
MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYR
Sbjct: 1 MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRGNTTMDIKDLVK 60
Query: 49 ------VEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT 102
VEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT
Sbjct: 61 QFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT 120
Query: 103 QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML 162
QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML
Sbjct: 121 QFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML 180
Query: 163 GKVSS 167
+S
Sbjct: 181 AMATS 185
>gi|24797110 calcium-binding tyrosine phosphorylation-regulated
protein isoform d [Homo sapiens]
Length = 281
Score = 169 bits (429), Expect = 4e-42
Identities = 83/87 (95%), Positives = 84/87 (96%)
Query: 81 MEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPP 140
MEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPP
Sbjct: 1 MEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPP 60
Query: 141 TAVSPEFAYVPADPAQLAAQMLGKVSS 167
TAVSPEFAYVPADPAQLAAQML +S
Sbjct: 61 TAVSPEFAYVPADPAQLAAQMLAMATS 87
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 58.5 bits (140), Expect = 1e-08
Identities = 115/470 (24%), Positives = 168/470 (35%), Gaps = 91/470 (19%)
Query: 58 PQKKLECLKEPGKTSVESKVPTQMEKSTDT----DEDNVTRTEYSDKTTQFPSVYAVPGT 113
P+ L C P TS+ES V + + T E T SD TT FPS T
Sbjct: 79 PRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPS-----ST 133
Query: 114 EQTEAVGGLSSKPATPK-TTTPPSSPPPTAVSPEFAYVPADPA---QLAAQMLGKV---- 165
E T S P TP+ T P S+P ++S A+V P + + KV
Sbjct: 134 EDT-------SSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMST 186
Query: 166 ---------SSIHSDQSDVLMVDV-------ATSMPVVIKEVPSSEAAEDVMVAAPLVCS 209
SS + +S + TSMP +V SSEA ++ P
Sbjct: 187 PLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAI--TLLTTP---- 240
Query: 210 GKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEV 269
V++ ++ S P E PS ++S P P V L E
Sbjct: 241 -----VEISTPVTISAQASSSPTTAEG-PSLSNSAP--SGGSTPLTRMPLSVMLVVSSEA 292
Query: 270 MSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSV 329
ST+ + ++PV E P T + + + + E +P S
Sbjct: 293 -STLSTTPAATNIPVITST-------EASSSPTTAEGTSIPTSTYT-EGSTPLTSTPAST 343
Query: 330 VEKTTSGMSKKSVESVKLAQL-EENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAE 388
+ TS MS S+ V + L + + SS+ AEAT++L+ T +G P +
Sbjct: 344 MPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEG--STPLTNMPVS 401
Query: 389 GAIKIGSEKSLHLEVEITSIV----------SDNTGQEESGENSVPQE---------MEG 429
+ SE S + + S S T ++ S S P E +
Sbjct: 402 TILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVST 461
Query: 430 KPVLSGEAAE----AVHSGTSVKSS--SGPFPPAPEGLTAPEIEPEGEST 473
PV S EA+ V S T V +S + PP E + P P ST
Sbjct: 462 TPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGST 511
Score = 43.5 bits (101), Expect = 4e-04
Identities = 92/472 (19%), Positives = 167/472 (35%), Gaps = 83/472 (17%)
Query: 16 TLLEGISRAVLKTNPSNINQFAAAYFQ--------ELTMYRVEKWSEGTTPQKKLECLKE 67
T++ + L T P++ + Y Q + T +SEG+TP
Sbjct: 1052 TMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPL-------- 1103
Query: 68 PGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPA 127
TSV V T++ S++ + T + S +P T TEA SS P
Sbjct: 1104 ---TSVP--VSTRLVVSSEASTLSTTPVDTS-----------IPVTTSTEA----SSSPT 1143
Query: 128 TPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVV 187
T + T+ P+SPP +P A +P + + +S+ D + S P
Sbjct: 1144 TAEGTSIPTSPPSEGTTP-LASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPP 1202
Query: 188 IKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQ 247
EV S + + PL + H + S + +S P+
Sbjct: 1203 TAEVTSMPTSTPGERSTPL-----------TSMPVRHTPVASSEASTLSTSPVDTSTPVT 1251
Query: 248 DEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVA 307
E +P + +T S++ +PV+ +V + + P +
Sbjct: 1252 TSAET---SSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGP 1308
Query: 308 CLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATA 367
+ NE S SP + + + +T + + S+ + ++ + + A +
Sbjct: 1309 VVTSNEVS----SSPTPAEGTSMPTSTYSEGRTPLTSIPV---------NTTLVASSAIS 1355
Query: 368 LLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQEM 427
+LS T + V S E TS+ + N + + S+P +
Sbjct: 1356 ILSTTPVDNSTPVTTST----------EACSSPTTSEGTSMPNSNPSEGTTPLTSIP--V 1403
Query: 428 EGKPVLSGEA----AEAVHSGT--SVKSSSGPFPPAPEGLTAPEIEP-EGES 472
PV+S EA A V + T + + + P EG++ P P EG++
Sbjct: 1404 STTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKT 1455
Score = 43.1 bits (100), Expect = 5e-04
Identities = 59/245 (24%), Positives = 87/245 (35%), Gaps = 55/245 (22%)
Query: 16 TLLEGISRAVLKTNPSNINQFAAAYFQ--------ELTMYRVEKWSEGTTPQKKLECLKE 67
T++ + L T P++ + Y Q + T +SEG+TP +
Sbjct: 2348 TMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTM 2407
Query: 68 PGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPA 127
P V S+ T DT + P T TEA SS P
Sbjct: 2408 P---VVSSEASTHSTTPVDT---------------------STPVTTSTEA----SSSPT 2439
Query: 128 TPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVV 187
T + T+ P+SPP +P A +P + + G +S+ VD +T M
Sbjct: 2440 TAEGTSIPTSPPSEGTTP-LASMPVSTTPVVSSEAGTLST--------TPVDTSTPMTTS 2490
Query: 188 IKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQ 247
+ S AED++V G L TS+ V S E ST S+ P+
Sbjct: 2491 TEASSSPTTAEDIVVPISTASEGSTL------LTSIPV---STTPVASPEASTLSTTPV- 2540
Query: 248 DEQEP 252
D P
Sbjct: 2541 DSNSP 2545
Score = 41.6 bits (96), Expect = 0.002
Identities = 107/439 (24%), Positives = 157/439 (35%), Gaps = 85/439 (19%)
Query: 54 EGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGT 113
EG+TP L + + V S+ T DT T TE + T ++P +
Sbjct: 921 EGSTP---LTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGT-SIPTS 976
Query: 114 EQTEAVGGLSSKPA---------------------TPKTT-TPPSSPPPTAVSPEFAYVP 151
+E L+S P TP TT T SSPPPTA E +P
Sbjct: 977 TPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTA---EGTSMP 1033
Query: 152 ADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGK 211
+S S+ S L T MPV V SSE + + P S
Sbjct: 1034 --------------TSTPSEGSTPL-----TRMPVSTTMVASSETS--TLSTTPADTSTP 1072
Query: 212 VLEVQVVNQTSVHVDLGSQPKENEAEPST-ASSVPLQDEQEPPAYDQAPEVTLQADIEVM 270
V + +S D S P +E ST +SVP+ + + + ++ +
Sbjct: 1073 VTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPV-----------STRLVVSSEASTL 1121
Query: 271 STVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENE--QSPRVSPKS 328
ST + + +PVT E P T + + + S+ S VS
Sbjct: 1122 STTPVDT---SIPVTTST-------EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTL 1171
Query: 329 VVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAE 388
VV + +S V+S Q+ + + SS AE T++ TS G+ P +
Sbjct: 1172 VVSSEANTLSTTPVDS--KTQVATSTEASSPPPTAEVTSM--PTSTPGERSTPLTSMPVR 1227
Query: 389 GAIKIGSEKSLHLEVEITSIVSDNTGQEESGE-NSVPQEMEGKPVLSGEAAEAVHSGTSV 447
SE S TS V +T S E +S P EG + + +E TS+
Sbjct: 1228 HTPVASSEAS----TLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSI 1283
Query: 448 KSSSG--PFPPAPEGLTAP 464
S+ P A LT P
Sbjct: 1284 PVSTTLVTSPEASTLLTTP 1302
Score = 41.2 bits (95), Expect = 0.002
Identities = 100/465 (21%), Positives = 162/465 (34%), Gaps = 79/465 (16%)
Query: 16 TLLEGISRAVLKTNP--------SNINQFAAAYFQELTMYRVEKWSEGTTPQKKLECLKE 67
TLL + L T P ++ ++ E T R+ S+G+TP +
Sbjct: 2702 TLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTL 2761
Query: 68 PGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPA 127
P +S S V T + DT ++P T TEA SS P
Sbjct: 2762 PVASSEASTVSTT---AVDT---------------------SIPVTTSTEA----SSSPT 2793
Query: 128 TPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVV 187
T + T+ P+S P +P +P + +A+ G +S+ VD +T +
Sbjct: 2794 TAEVTSMPTSTPSETSTP-LTSMPVNHTPVASSEAGTLST--------TPVDTSTPVTTS 2844
Query: 188 IKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQ 247
K S AE ++V G L + T+ + S + +S+P+
Sbjct: 2845 TKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTT---PVASSEASTLSTTPVDTSIPVT 2901
Query: 248 DEQE---PPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVT-EGVVYIEQLPEQIVIPFT 303
E P + + + EV ST S + + VPV + P P T
Sbjct: 2902 TSTEGSSSPTTAEGTSMPISTPSEV-STPLTSILVSTVPVAGSEASTLSTTPVDTRTPVT 2960
Query: 304 DQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEA 363
S E SP + + + +T G + + S+ ++ + + +S
Sbjct: 2961 ----------TSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRT 3010
Query: 364 EATALLSDTSLKGQPEVPAQLLDAEGA---IKIGSEKSLHLEVEITSIVSDNTG---QEE 417
A + T + E + AEG I SE S +TSI T E
Sbjct: 3011 PAD---TSTPVTTSTEASSSPTTAEGTGIPISTPSEGS----TPLTSIPVSTTPVAIPEA 3063
Query: 418 SGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLT 462
S ++ P + V S E + S T + +S P EG T
Sbjct: 3064 STLSTTPVDSNSPVVTSTEVSS---SPTPAEGTSMPISTYSEGST 3105
Score = 35.0 bits (79), Expect = 0.15
Identities = 94/463 (20%), Positives = 160/463 (34%), Gaps = 56/463 (12%)
Query: 2 ISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQEL------TMYRVEKWSEG 55
+SS P + T R L + P + A++ L T V +S+
Sbjct: 1904 VSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQA 1963
Query: 56 TTPQKKLECLKEPGKTSVESKVP-TQMEKSTD---TDEDNVTRTEYSDKTTQFPSVYAVP 111
++ + P E P T M ST + E + T D +T P+ +
Sbjct: 1964 SSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTST--PATTSTE 2021
Query: 112 GTEQTEAVGGLSSKPATPKTTTPPSSPPPTA----VSPEFAYVPADPAQLAAQMLGKVSS 167
G+ GG S + +TP T P + P + VS E + P Q+ +
Sbjct: 2022 GSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEA 2081
Query: 168 IHSDQSDVLMVDVA---------TSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVV 218
S ++ + ++ TS+P+ V S EA+ + P+ + V+
Sbjct: 2082 SSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEAS--TLSTTPVDSNSPVI----- 2134
Query: 219 NQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSV 278
TS V P E T+ ++ P T+ A +ST+ + V
Sbjct: 2135 --TSTEVSSSPIPTE-----GTSMQTSTYSDRRTPLTSMPVSTTVVAS-SAISTLSTTPV 2186
Query: 279 YNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENE--QSPRVSPKSVVEKTTSG 336
PVT E P T + + + S+ + S VS VV S
Sbjct: 2187 DTSTPVTNST-------EARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEAST 2239
Query: 337 MSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSE 396
+S V++ + + + +S AE T++ + T +G P + + SE
Sbjct: 2240 LSATPVDT--STPVTTSTEATSSPTTAEGTSIPTSTLSEG--TTPLTSIPVSHTLVANSE 2295
Query: 397 KSLHLEVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAE 439
S + S T E S S P EG + + ++E
Sbjct: 2296 VSTLSTTPVDSNTPFTTSTEAS---SPPPTAEGTSMPTSTSSE 2335
Score = 34.7 bits (78), Expect = 0.19
Identities = 91/419 (21%), Positives = 145/419 (34%), Gaps = 56/419 (13%)
Query: 68 PGKTSVESKVP-TQMEKSTD---TDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLS 123
P T E P T M ST + ED+ D +T P T TEA
Sbjct: 3155 PTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTST--------PVTTSTEA----- 3201
Query: 124 SKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATS 183
+ T + T+ P+S P ++P VP +A+ +S+ D + L S
Sbjct: 3202 TSSTTAEGTSIPTSTPSEGMTP-LTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS 3260
Query: 184 MPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPST--- 240
E S + + PL ++TS L + P + +T
Sbjct: 3261 SSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETST---LSTTPADTSTPVTTYSQ 3317
Query: 241 -ASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVT--EGVVYIEQLPEQ 297
+SS P+ D P + T ++ +T +SS + + T + + E
Sbjct: 3318 ASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEA 3377
Query: 298 IVIPFTDQVACLKENEQSKENE--QSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAK 355
+ P T + + + S+ S VS VV + +S V+S L A
Sbjct: 3378 SLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEAS 3437
Query: 356 YSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKS------LHLEVEITSIV 409
S AE T+L + T+ +G P ++ SE S + +T+
Sbjct: 3438 SSPTI--AEGTSLPTSTTSEG--STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSS 3493
Query: 410 SDNTGQEESGENSVPQEMEGK-------------PVLSGEAA----EAVHSGTSVKSSS 451
N+ + S+P G+ PV S EA+ V S T V SSS
Sbjct: 3494 PTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSS 3552
Score = 34.7 bits (78), Expect = 0.19
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 4/63 (6%)
Query: 75 SKVPTQMEKSTDTDEDNVT----RTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPK 130
S PT ST + + VT RT+ S +TT FP+V T +S P P+
Sbjct: 4072 STPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPR 4131
Query: 131 TTT 133
TTT
Sbjct: 4132 TTT 4134
Score = 34.3 bits (77), Expect = 0.25
Identities = 96/427 (22%), Positives = 145/427 (33%), Gaps = 60/427 (14%)
Query: 71 TSVESKVP----TQMEKSTDTDEDNV----TRTEYSDKTTQFPSVYAVPGTEQTEAVGGL 122
T V+S P T+ S+ T E T TE S T P + + + +
Sbjct: 652 TPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTT 711
Query: 123 SSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVAT 182
+TP TT+ +S PT AD A + +S S+ S L T
Sbjct: 712 PVDTSTPVTTSTEASSSPTT---------ADGASMP-------TSTPSEGSTPL-----T 750
Query: 183 SMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPS--- 239
SMPV + SSEA+ + PL S + + + + S P +E S
Sbjct: 751 SMPVSKTLLTSSEAS--TLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLL 808
Query: 240 TASSVPLQDEQEPPA-------YDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIE 292
T+ V + P A D VT ++ T + +EG +
Sbjct: 809 TSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLT 868
Query: 293 QLPEQIVIPFTDQVACLK----ENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLA 348
+P + T ++ L + N R SP + E T+ S S L
Sbjct: 869 SMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSP-TTSEGTSMPTSTPGEGSTPLT 927
Query: 349 QLEENAK--YSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEIT 406
+ ++ SS AT + + T + E + AEG S S E T
Sbjct: 928 SMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPS-----EGT 982
Query: 407 SIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEI 466
+ ++ NS + PV S TS ++SS PP EG + P
Sbjct: 983 TPLTSTPVSHTLVANSEASTLSTTPVDSNTPLT-----TSTEASSP--PPTAEGTSMPTS 1035
Query: 467 EPEGEST 473
P ST
Sbjct: 1036 TPSEGST 1042
Score = 34.3 bits (77), Expect = 0.25
Identities = 74/355 (20%), Positives = 124/355 (34%), Gaps = 44/355 (12%)
Query: 53 SEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPG 112
SEGTTP + P V S+V T D++ T TE S T ++P
Sbjct: 3395 SEGTTPLASMPVSTTP---VVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGT-SLPT 3450
Query: 113 TEQTEAVGGLSSKP---------------ATP-KTTTPPSSPPPTAVSPEFAYVPADPAQ 156
+ +E LS P TP T+TP ++ PT SP A V + P
Sbjct: 3451 STTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTS 3510
Query: 157 LAAQ-------MLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCS 209
A + M + + S ++ L S V +S + + V + +
Sbjct: 3511 TAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMST 3570
Query: 210 ----GKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQA 265
L +++ T V S P + PS S P+ + + PEV
Sbjct: 3571 PSEGSSSLTTMLLSSTYVTSSEASTP----STPSVDRSTPVTTSTQSNSTPTPPEV---I 3623
Query: 266 DIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSK-----ENEQ 320
+ + + +S+ +PV+ V I + +P + + S E
Sbjct: 3624 TLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTT 3683
Query: 321 SPRVSP-KSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSL 374
P +P + TT +S V S + + L + +S + A+ S +L
Sbjct: 3684 MPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATL 3738
Score = 32.3 bits (72), Expect = 0.96
Identities = 97/463 (20%), Positives = 157/463 (33%), Gaps = 66/463 (14%)
Query: 37 AAAYFQELTMYRVEKWSEGTTPQKKLECLKEP---------GKTSVESKVPTQMEKST-- 85
++A E T +SEG+TP + + +P T V++ +P T
Sbjct: 2554 SSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSS 2613
Query: 86 ------DTDEDNVTRTEYSDKTTQF-----PSVYAVPGTEQTEAVG---------GLSSK 125
DT T +E S T P + T T V G SS
Sbjct: 2614 SPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSS 2673
Query: 126 PATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMP 185
P T + ++ P+S P +P L ++ +S+ S + V TS P
Sbjct: 2674 PTTAEGSSMPTSTPGERSTP-----------LTNILVSTTLLANSEASTLSTTPVDTSTP 2722
Query: 186 VVIKEVPSSE--AAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASS 243
V SS AE + G ++ T + + S + + +S
Sbjct: 2723 VTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVST---LPVASSEASTVSTTAVDTS 2779
Query: 244 VPLQDEQEPPAYDQAPEVTLQ--ADIEVMSTVHISSVYNDVPVTEGVV-YIEQLPEQIVI 300
+P+ E + EVT + ST S N PV + P
Sbjct: 2780 IPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTST 2839
Query: 301 PFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLE-ENAKYSSV 359
P T S + SP + VV +T+ + S+ ++ +++ S++
Sbjct: 2840 PVT----------TSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTL 2889
Query: 360 YMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESG 419
T++ TS +G P I SE S L + S V G E S
Sbjct: 2890 STTPVDTSIPVTTSTEGSSS-PTTAEGTSMPISTPSEVSTPLTSILVSTV-PVAGSEAST 2947
Query: 420 ENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLT 462
++ P + PV + +AEA S T+ + +S P E T
Sbjct: 2948 LSTTPVDTR-TPVTT--SAEASSSPTTAEGTSMPISTPGERRT 2987
Score = 31.2 bits (69), Expect = 2.1
Identities = 103/482 (21%), Positives = 165/482 (34%), Gaps = 69/482 (14%)
Query: 3 SSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRVEKWSEGTTPQKK- 61
SS P + T L + P + A++ L+ V+ ++ TT +
Sbjct: 431 SSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEAS 490
Query: 62 -----LECLKEPGKTSVESKVP-TQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQ 115
E P T E P T M ST V +E S +T P + P T
Sbjct: 491 SSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMP----VASSEASTLSTT-PVDTSTPVTTS 545
Query: 116 TEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDV 175
+EA SS TP+ T+ P+S P +P +P + + S+ +D +
Sbjct: 546 SEA----SSSSTTPEGTSIPTSTPSEGSTP-LTNMPVSTRLVVSSEASTTSTTPADSNTF 600
Query: 176 LMVDVATSMPVVIKE---VPSSEAAE------DVMVAAPLVCSGKVLEVQ---VVNQTSV 223
+ S E +P+S +E + V+ LV S + + V + T V
Sbjct: 601 VTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPV 660
Query: 224 HVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVP 283
+ AE T+ E P TL A E ST+ + V P
Sbjct: 661 TTSTEATSSSTTAE-GTSMPTSTYTEGSTPLTSMPVNTTLVASSEA-STLSTTPVDTSTP 718
Query: 284 VTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVE 343
VT E P T A + + S+ + T+ +SK +
Sbjct: 719 VTTST-------EASSSPTTADGASMPTSTPSEGS-----------TPLTSMPVSKTLLT 760
Query: 344 SVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQP---EVPAQLLDAEGAIKIGSEKSLH 400
S + + L +S ++ A S T+ +G P++ GS
Sbjct: 761 SSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSE----------GSPLLTS 810
Query: 401 LEVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEG 460
+ V IT + T E S ++ P + PV + + E S T + +S P EG
Sbjct: 811 IPVSITPV----TSPEASTLSTTPVD-SNSPVTT--STEVSSSPTPAEGTSMPTSTYSEG 863
Query: 461 LT 462
T
Sbjct: 864 RT 865
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 47.8 bits (112), Expect = 2e-05
Identities = 64/284 (22%), Positives = 105/284 (36%), Gaps = 44/284 (15%)
Query: 226 DLGSQPKENEAEPSTAS-SVPLQDEQEPPAYD--QAPEVTLQADIEVMSTVHISSVYNDV 282
D+ + E EA+P + P + + P + +APE +A E S + + D
Sbjct: 1873 DVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDE 1932
Query: 283 PVTEGV---------------------VYIEQLPEQIVIPFTDQVACLKENEQSKENEQS 321
P +EG V Q E+ P ++ V L+ +++E E
Sbjct: 1933 PESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGE 1992
Query: 322 PRVSPKSVVEKTTSGMSKKS----------VESVKLAQLEENAKYSSVYMEAEATALLSD 371
+ + V G +++ VE+ ++ EE + + E A
Sbjct: 1993 AQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPES 2052
Query: 372 TSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQEMEGKP 431
++ PE + +AEG ++ +E H E E D QE GE E P
Sbjct: 2053 DGVEA-PEAEEEAQEAEGEVQ-EAEGEAHPESE------DVDAQEAEGEAQPESEGVEAP 2104
Query: 432 VLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE 475
GEA +A G + G P EG+ APE E E + +E
Sbjct: 2105 EAEGEAQKA--EGIEAPETEGEAQPESEGIEAPEAEGEAQPESE 2146
Score = 42.4 bits (98), Expect = 0.001
Identities = 91/406 (22%), Positives = 146/406 (35%), Gaps = 47/406 (11%)
Query: 74 ESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTT 133
E + + E + + + E D T P +E EA + K A P+T +
Sbjct: 1864 EGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPE--AEKEAQPETES 1921
Query: 134 PPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPS 193
+ PE A A+ AAQ + +S+V + S
Sbjct: 1922 VEALETEGEDEPESEGAEAQEAEEAAQ---EAEGQTQPESEV---------------IES 1963
Query: 194 SEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPP 253
EA E+ A P + LEV+V Q + + +QP+ + E A + E+E
Sbjct: 1964 QEAEEE---AQPESEDVEALEVEVETQEA---EGEAQPESEDVEAPEAEGEMQEAEEEAQ 2017
Query: 254 AYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENE 313
E +++ E V + TEG E + + P ++ A E E
Sbjct: 2018 PESDGVEAQPKSEGE-----EAQEVEGETQKTEGDAQPES--DGVEAPEAEEEAQEAEGE 2070
Query: 314 -QSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDT 372
Q E E P + V + G ++ E V+ + E A+ +AE +T
Sbjct: 2071 VQEAEGEAHPE--SEDVDAQEAEGEAQPESEGVEAPEAEGEAQ------KAEGIEA-PET 2121
Query: 373 SLKGQPEVPA-QLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQEMEG-- 429
+ QPE + +AEG + SE + E + + + E E+EG
Sbjct: 2122 EGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVE 2181
Query: 430 KPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE 475
P GEA + G + G P EG+ APE E E + E
Sbjct: 2182 APEAEGEA-QPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPE 2226
Score = 37.7 bits (86), Expect = 0.023
Identities = 41/168 (24%), Positives = 67/168 (39%), Gaps = 9/168 (5%)
Query: 314 QSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTS 373
Q E P +S V++ G + + K +L E A+ ++ E E S+TS
Sbjct: 1724 QGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGE-AEGDAMAQEREGKTHNSETS 1782
Query: 374 LK---GQPEVPAQLLDAEGAIKIGSEKSLH---LEVEITSIVSDNTGQEESGENSVPQEM 427
G+ E + + G + G + S H L+ E + + GQ + E E
Sbjct: 1783 AGSELGEAEQEGEGISERG--ETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEA 1840
Query: 428 EGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE 475
EG+ E EA + + + G P E + APE E E + +E
Sbjct: 1841 EGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESE 1888
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 42.7 bits (99), Expect = 7e-04
Identities = 104/455 (22%), Positives = 149/455 (32%), Gaps = 77/455 (16%)
Query: 54 EGTTPQKKLECLKEPGKTSVE--SKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVP 111
EG K L+ LK+P T + +VPT + K T + +R PS
Sbjct: 500 EGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRK 559
Query: 112 GTEQTEAVGGLSSKPATPKTTTPPS-SPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHS 170
SK TP+ T PP S E V D
Sbjct: 560 -----------ESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKP--------------- 593
Query: 171 DQSDVLMVDVATSMPVVIKEVPSSEA-----AEDVMVAAPLVCSGKVLEVQVVNQTSVHV 225
+ T V KEVPS E AE A V E V +T V
Sbjct: 594 -------IKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKP 646
Query: 226 DLGSQPKENEAEP--STASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVP 283
+ + KE + P++ E++P + EV + E V + P
Sbjct: 647 EDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPK-KEVKKETP 705
Query: 284 VTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVE 343
E +++ ++ V +E E KE ++ P+ + KS S K +
Sbjct: 706 PKEVKKEVKKEEKKEVKK--------EEKEPKKEIKKLPKDAKKS--STPLSEAKKPAAL 755
Query: 344 SVKLAQLEENAKYSSV------------YMEAEATALLSDTSLKGQPEVPAQLLDAEGAI 391
K+ + EE+ K SV ++ E A + + G A ++ A G
Sbjct: 756 KPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIA 815
Query: 392 KIGSEKSLHLEVEITSIVSDNTGQ-EESGENSVPQEMEGKPVLS----------GEAAEA 440
IG K L E + S D T EE V + KP L E EA
Sbjct: 816 AIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEA 875
Query: 441 VHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE 475
+ + GP EG+T E E E E T E
Sbjct: 876 YVIQKEREVTKGPAESPDEGITTTEGEGECEQTPE 910
Score = 35.4 bits (80), Expect = 0.11
Identities = 80/417 (19%), Positives = 150/417 (35%), Gaps = 48/417 (11%)
Query: 81 MEKSTDTDEDNVTRTEYSDKTTQFPSV--YAVPGTEQTEAV-------------GGLS-- 123
+EK+T T E+ + S+KTT P V Y+ TE++ + GG +
Sbjct: 1943 IEKTTRTPEEGGYSYDISEKTTSPPEVSGYSYEKTERSRRLLDDISNGYDDSEDGGHTLG 2002
Query: 124 ----SKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVD 179
S T K T+ P S + + D + + K++ + Q+ +
Sbjct: 2003 DPSYSYETTEKITSFPESEGYSYETSTKTTRTPDTSTYCYETAEKIT--RTPQASTYSYE 2060
Query: 180 VATSMPVVIKEVPSSEAAEDVMVAAPLVCSGK----VLEVQVVNQTSVHVDLGSQPKENE 235
+ K+ P SEA +DV + C K L +N + +P E
Sbjct: 2061 TSDLCYTAEKKSP-SEARQDVDLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEPTEES 2119
Query: 236 AEPSTASS---VPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIE 292
+P T S P +Q+ D+ P ++ + + + P I+
Sbjct: 2120 EKPLTQSGGAPPPPGGKQQGRQCDETPPTSVSESAPSQTDSDVPPETEECPSITADANID 2179
Query: 293 QLPEQIVIPFTDQVACLKENEQS----KENEQSPRVSPKSVVEKTTSGMSKKSVESVKLA 348
E IP TD+ K + ++ SPR S+V+ + + +++K
Sbjct: 2180 SEDESETIP-TDKTVTYKHMDPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKALK-K 2237
Query: 349 QLEENAKYSSVYMEAEATALLSDTSLKGQP----EVPAQLLDAEGAIKIGSEKSLHLEVE 404
L+E K + ++++ + + K +P PA L E + K+ S +
Sbjct: 2238 DLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGL--KESSDKVSRVASPKKKES 2295
Query: 405 ITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHS-----GTSVKSSSGPFPP 456
+ T E ++ E K + A+++ + GT+ + S PP
Sbjct: 2296 VEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKSSAVPP 2352
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 5/69 (7%)
Query: 83 KSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTA 142
K T T E R E DK T+ + + + +T G P T KTT + PP
Sbjct: 2301 KPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAG-----PGTTKTTKSSAVPPGLP 2355
Query: 143 VSPEFAYVP 151
V + Y+P
Sbjct: 2356 VYLDLCYIP 2364
>gi|8394343 sperm autoantigenic protein 17 [Homo sapiens]
Length = 151
Score = 42.4 bits (98), Expect = 0.001
Identities = 18/35 (51%), Positives = 24/35 (68%)
Query: 10 VPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQEL 44
+P G LLEG++R +L+ P NI FAAAYF+ L
Sbjct: 12 IPQGFGNLLEGLTREILREQPDNIPAFAAAYFESL 46
>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3
[Homo sapiens]
Length = 1585
Score = 41.6 bits (96), Expect = 0.002
Identities = 78/404 (19%), Positives = 135/404 (33%), Gaps = 83/404 (20%)
Query: 113 TEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQ 172
T +T A+ ++ P P TT S T +P + + + P A + + S +
Sbjct: 250 TSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTA--IDDRCELSSPR 307
Query: 173 SDVLMVDVATSMPVVIKEVPSSEAAEDVMVAA--------PLVCSGKVLE---------- 214
D + + TS +P++E +D+ PLV S ++
Sbjct: 308 EDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLS 367
Query: 215 -----VQVVNQTSVHVDLGSQPKENEAE------------PSTASSVPLQDEQEPPAYDQ 257
V++V Q + + L + EN E PST S P P +
Sbjct: 368 ATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPH 427
Query: 258 APEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKE 317
P + A V S +V + E + CL E+ + +
Sbjct: 428 TPVIVPAAATTVSSPSAAITVQRVLEEDESIR-----------------TCLSEDAKEIQ 470
Query: 318 NEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQ 377
N+ +E G +++ ++S L N++ S V + T + K +
Sbjct: 471 NK----------IEVEADGQTEEILDSQNL-----NSRRSPVPAQIAITVPKTWKKPKDR 515
Query: 378 PEVPAQLLDAEGAIKIGSEKSLHLEVEIT--------------SIVSDNTGQEESGENSV 423
++L+AE +K E S+ +E S + EE+GE +
Sbjct: 516 TRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAE 575
Query: 424 PQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIE 467
P + V GE +A T FP PE + E
Sbjct: 576 PVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTE 619
>gi|19923559 EMSY protein [Homo sapiens]
Length = 1322
Score = 40.0 bits (92), Expect = 0.005
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 23/263 (8%)
Query: 123 SSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVL-----M 177
+S +TP +T PS T SP A ++ L + V S+ D
Sbjct: 147 TSTTSTPTSTPVPSGSIATVKSPRPASPASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRR 206
Query: 178 VDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEV--QVVNQTSVHVDLGSQPKENE 235
+ ++S PVV+KEVP + + P+ S K+ + + N H+ S K
Sbjct: 207 TNSSSSSPVVLKEVPKAVVPVSKTITVPVSGSPKMSNIMQSIANSLPPHM---SPVKITF 263
Query: 236 AEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLP 295
+PST ++ Q+ +P T +I +S H + + T + Q P
Sbjct: 264 TKPSTQTT--NTTTQKVIIVTTSPSSTFVPNI--LSKSHNYAAVTKLVPTSVIASTTQKP 319
Query: 296 EQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAK 355
++ T + L N S + +P P +V T+ +S S SV ++ + +
Sbjct: 320 PVVI---TASQSSLVSNSSSGSSSSTPSPIPNTVA--VTAVVS--STPSVVMSTVAQGVS 372
Query: 356 YSSVYMEAEATALLSDTSLKGQP 378
S++ M +T L S SL P
Sbjct: 373 TSAIKM--ASTRLPSPKSLVSAP 393
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 39.7 bits (91), Expect = 0.006
Identities = 93/431 (21%), Positives = 145/431 (33%), Gaps = 77/431 (17%)
Query: 104 FPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPP-----------------PTAVSPE 146
+P V VP +E+ + L S A TT P S PP P A SP
Sbjct: 1228 YPKVATVPQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPA 1287
Query: 147 FAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDV---ATSMPVVIKEVPSSEA------- 196
A A A AA +S + + ++ + S +E P S A
Sbjct: 1288 TAATTAAAASTAASSTASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPK 1347
Query: 197 --AEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQP--KENEAEPSTASSVPLQDEQEP 252
AED + A PL+ Q ++ + +P E E +P A L +
Sbjct: 1348 TTAEDGVPAPPLLDPIVQQFGQFSKDKALEEEEDDRPYDPEEEYDPERAFDTQLVERGRR 1407
Query: 253 PAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKEN 312
++APE EV ++ + VT ++ LP ++ C
Sbjct: 1408 HEVERAPEAAAAEREEVAYDPEDETILEEAKVT-----VDDLPNRM---------CADVR 1453
Query: 313 EQSKENEQSP---RVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATAL- 368
S E P +P V ++ K +E K QLEE + A ++
Sbjct: 1454 RNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQK-RQLEEQEEALRQQRAAVGVSMA 1512
Query: 369 ---LSDTSLKGQP----------EVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQ 415
+SD + P + Q D ++ S+ S H + ++ TG+
Sbjct: 1513 HFSVSDALMSPPPKSSLPKAELFQQEQQSADKPASLPPASQASNHRDPRQARRLAAETGE 1572
Query: 416 EE----------SGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSS---SGPFPPAPEGLT 462
E + ++P+ + L G+A V SS SG PPA
Sbjct: 1573 GEGEPLSRLSARGAQGALPERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAGSEQD 1632
Query: 463 APEIEPEGEST 473
+ EP GE T
Sbjct: 1633 GWKAEP-GEGT 1642
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 38.9 bits (89), Expect = 0.010
Identities = 90/395 (22%), Positives = 136/395 (34%), Gaps = 79/395 (20%)
Query: 67 EPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQ---------FPSVYAVPGTEQTE 117
EP + + E +V T +E+ +E+ E T + P V P E+ +
Sbjct: 9904 EPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKK 9963
Query: 118 AVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHS-----DQ 172
V P K PP+ P PE VP + KV + ++
Sbjct: 9964 PV------PVPKKKEAPPAKVPEVPKKPE-EKVPVLIPKKEKPPPAKVPEVPKKPVPEEK 10016
Query: 173 SDVLMVDVATSMPVVIKEVPSSEAAED-VMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQP 231
V + + P + EVP E V V AP +V V P
Sbjct: 10017 VPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEV------------P 10064
Query: 232 KENEAEPSTASSVPLQDEQEPPAYDQAPE-----VTLQADIEVMSTVHISSVYNDVPVTE 286
K+ E + VP + E PP + E V L + EV+ I +P E
Sbjct: 10065 KKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEE 10124
Query: 287 GVVYIEQ---------LPEQIVIPFTDQVA------CLKENEQSKENEQSPRVSPKSVVE 331
V+ E+ LPE+ IP ++ +E E E E P V PK V
Sbjct: 10125 EVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVP 10184
Query: 332 KTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAI 391
+ KK E + +E A + V PEVP ++ E I
Sbjct: 10185 APVPEIKKKVTEKKVVIPKKEEAPPAKV------------------PEVPKKV--EEKRI 10224
Query: 392 KIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQE 426
+ E+ + L VE+T + +E E +P+E
Sbjct: 10225 ILPKEEEV-LPVEVT----EEPEEEPISEEEIPEE 10254
Score = 33.9 bits (76), Expect = 0.33
Identities = 49/222 (22%), Positives = 82/222 (36%), Gaps = 50/222 (22%)
Query: 50 EKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYA 109
E+W E ++ ++ KE + S E KVP ++ + K P V
Sbjct: 9138 EEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEK---------------KAPPPPKVIK 9182
Query: 110 VPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIH 169
P E+ E + T P S VP P++ + +
Sbjct: 9183 KPVIEKIEKTSRRMEEEKVQVTKVPEVSK---------KIVPQKPSR---------TPVQ 9224
Query: 170 SDQSDVLMVDVATSMPVVIKEVP--SSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDL 227
+ +V + V T V+ +E +S E+V V P V + ++V + +HV +
Sbjct: 9225 EEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEV------QKEIVTEEKIHVAI 9278
Query: 228 GSQ----PKENE----AEPSTASSVPLQDEQEPPAYDQAPEV 261
+ PK E P + VP+ + EPPA + PEV
Sbjct: 9279 SKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPA-PKVPEV 9319
Score = 33.5 bits (75), Expect = 0.43
Identities = 81/346 (23%), Positives = 125/346 (36%), Gaps = 71/346 (20%)
Query: 43 ELTMYRVEKWSEGTTPQKKLECLKEPGKTSVE-SKVPTQMEKSTDTDEDNVTRTEYSDKT 101
E+T +V + + P+KK+ + P K V +KVP + + E V
Sbjct: 10603 EVTPVKVPEAPKEVVPEKKVP-VPPPKKPEVPPTKVPEVPKVAVP--EKKVPEAIPPKPE 10659
Query: 102 TQFPSVYAVP---GTEQTEAVGGLSSKPATP-KTTTPPSSPPPTAVSPEFAYVPADPAQL 157
+ P V+ P E+ A +PA P + T PP P P +P V A +L
Sbjct: 10660 SPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPA---VVAKKPEL 10716
Query: 158 AAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEV-- 215
+P V KEV + V+ P KV EV
Sbjct: 10717 P----------------------PVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPK 10754
Query: 216 QVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHI 275
+VV + V V PK+ E P+ VP + P ++ P V + E
Sbjct: 10755 EVVPEKKVAV-----PKKPEVPPAKVPEVP-----KKPVLEEKPAVPVPERAE------- 10797
Query: 276 SSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTS 335
P E VY E PE+I +++A +E E+ P V P +V E+
Sbjct: 10798 ------SPPPE--VYEE--PEEIAP--EEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKK 10845
Query: 336 GMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVP 381
+ +K V +K + + E E ++ LK +P P
Sbjct: 10846 IIPEKKVPVIKKPE-------APPPKEPEPEKVIEKPKLKPRPPPP 10884
Score = 33.5 bits (75), Expect = 0.43
Identities = 35/165 (21%), Positives = 67/165 (40%), Gaps = 13/165 (7%)
Query: 305 QVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAE 364
Q K E ++ N + ++ + V E T S + E ++ ++E +A V +
Sbjct: 25062 QFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRA 25121
Query: 365 ATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGENSVP 424
+ L ++KG+PE + AEG + + + T +V DN + +SG ++
Sbjct: 25122 SATLRLFVTIKGRPEPEVKWEKAEGILT--DRAQIEVTSSFTMLVIDNVTRFDSGRYNLT 25179
Query: 425 QEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPE 469
E + ++ V S P AP LT E++ +
Sbjct: 25180 LE-------NNSGSKTAFVNVRVLDS----PSAPVNLTIREVKKD 25213
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 38.9 bits (89), Expect = 0.010
Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 16/112 (14%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEK---STDTDEDNVTRTEYSDKTTQFPSVYAVPG 112
TTP++ KEP T+ + PT +K +T + T E + TT+ PS P
Sbjct: 328 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS----PT 383
Query: 113 TEQTEAVGGLSSKPATPKTTTP---------PSSPPPTAVSPEFAYVPADPA 155
T + A S P T K P P P PT P +PA
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/92 (27%), Positives = 32/92 (34%), Gaps = 2/92 (2%)
Query: 66 KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSK 125
KEP T+ + PT +K T T + + T P A E+
Sbjct: 472 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 531
Query: 126 PATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
P TPK P P P PT P +PA
Sbjct: 532 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Score = 37.7 bits (86), Expect = 0.023
Identities = 71/363 (19%), Positives = 118/363 (32%), Gaps = 49/363 (13%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTE 114
TTP++ KE T+ + PT +++ T E + TT+ P+
Sbjct: 557 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 616
Query: 115 QTEAVGGLSSKPATPKTTTP----PSSPPPTAVSPEFAYVPADPAQLAAQML------GK 164
T G + P P TTP P++P TA + P P + A + L G
Sbjct: 617 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 676
Query: 165 VSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVH 224
S+ + + A + P + A P S T++H
Sbjct: 677 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 736
Query: 225 -------VDLGSQPKENEAE--------PSTASSVPLQDEQEPPAYDQ--------APEV 261
+L ++P E P+T + + E A D+ PE
Sbjct: 737 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 796
Query: 262 TLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQS 321
T A T + + +T + Q PF ++ LK +
Sbjct: 797 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF--KITTLK----------T 844
Query: 322 PRVSPKSVVEK---TTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQP 378
++PK K TT+ + K E+ K N+K ++ + A TS K
Sbjct: 845 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 904
Query: 379 EVP 381
+P
Sbjct: 905 TMP 907
Score = 35.8 bits (81), Expect = 0.087
Identities = 30/109 (27%), Positives = 41/109 (37%), Gaps = 9/109 (8%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKS-TDTDEDNVTRTEYSDKTTQFPSVYAVPGT 113
TTP++ KEP T+ + PT + + T T E T T+ + T + PS
Sbjct: 367 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 426
Query: 114 EQTEAVGGLSSKPATPKTTTP-------PSSPPPTAVSPEFAYVPADPA 155
T + P P TTP P P PT P +PA
Sbjct: 427 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 8/108 (7%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT---QFPSVYAVP 111
TTP++ KEP T+ + PT ++ + T ++ T S TT P+ P
Sbjct: 211 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 270
Query: 112 GTEQTEAVGGLSSKPATPKTT----TPPSSPPPTAVSPEFAYVPADPA 155
+ ++K P TT T P P PT P +PA
Sbjct: 271 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 318
Score = 35.0 bits (79), Expect = 0.15
Identities = 27/103 (26%), Positives = 36/103 (34%), Gaps = 3/103 (2%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTE 114
TTP++ KEP T+ + PT ++ T T T P A E
Sbjct: 445 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 504
Query: 115 QTEAVGGLSSKPATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
+ P TP+ TP P P PT P +PA
Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 547
Score = 33.1 bits (74), Expect = 0.57
Identities = 61/323 (18%), Positives = 104/323 (32%), Gaps = 49/323 (15%)
Query: 66 KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSK 125
KEP T+ + PT +++ T T + P A T S+
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611
Query: 126 PATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMP 185
P TTP + P T P P +PA + + P
Sbjct: 612 CDKPAPTTPKGTAPTTPKEPA-PTTPKEPAPTTPK---------------------GTAP 649
Query: 186 VVIKE-VPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASS- 243
+KE P++ AP G TS D + E P+T
Sbjct: 650 TTLKEPAPTTPKKPAPKELAPTTTKG---------PTSTTSDKPAPTTPKETAPTTPKEP 700
Query: 244 VPLQDEQEPPAYDQAP-----EVTLQADIEVMSTVHISSVYN--DVPVTEGVVYIEQLPE 296
P ++ P + P EV+ + +T+H S + ++ +E P+
Sbjct: 701 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 760
Query: 297 QIVIPFTDQVACLK----ENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEE 352
+ +P T A K + K E+ R +P +TT+ K + E+ +
Sbjct: 761 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-----ETTTAAPKMTKETATTTEKTT 815
Query: 353 NAKYSSVYMEAEATALLSDTSLK 375
+K ++ + +T T K
Sbjct: 816 ESKITATTTQVTSTTTQDTTPFK 838
Score = 32.3 bits (72), Expect = 0.96
Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 9/105 (8%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRT--EYSDKTTQFPSVYAVPG 112
TTP++ KEP T+ +S T E + T + T E + T + P+ P
Sbjct: 273 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PT 328
Query: 113 TEQTEAVGGLSSKPATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
T + A P TPK P P P PT P +PA
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/91 (24%), Positives = 32/91 (35%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQ 115
TT + KEP T+ + PT ++ T T + P A T++
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465
Query: 116 TEAVGGLSSKPATPKTTTPPSSPPPTAVSPE 146
P TPK T P + T +PE
Sbjct: 466 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 496
Score = 31.6 bits (70), Expect = 1.6
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEKS--TDTDEDNVTRTEYSDKTTQFPSVYAVPGT 113
TT + KEP T+ + PT ++ T T E T T+ + T + P+ P T
Sbjct: 250 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA----PTT 305
Query: 114 EQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPE 146
+ A P TPK P + PT +P+
Sbjct: 306 PKKPA-------PTTPKEPAPTTPKEPTPTTPK 331
Score = 30.4 bits (67), Expect = 3.7
Identities = 36/153 (23%), Positives = 54/153 (35%), Gaps = 21/153 (13%)
Query: 70 KTSVESKVPTQMEKSTDTDEDNVT----RTEYSDKTT-----QFPSVYAVPGTE-QTEAV 119
+T+VE+K T K T TD T T+ +KT+ V A P + +T
Sbjct: 147 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 206
Query: 120 GGLSSKPATPKTTTP-------PSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQ 172
G + P P TTP P P PT + P P + A + +
Sbjct: 207 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS----APTTPKEPAPTTTKSAPTTPKEP 262
Query: 173 SDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAP 205
+ + A + P + E A +AP
Sbjct: 263 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 295
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 38.9 bits (89), Expect = 0.010
Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 16/112 (14%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEK---STDTDEDNVTRTEYSDKTTQFPSVYAVPG 112
TTP++ KEP T+ + PT +K +T + T E + TT+ PS P
Sbjct: 369 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS----PT 424
Query: 113 TEQTEAVGGLSSKPATPKTTTP---------PSSPPPTAVSPEFAYVPADPA 155
T + A S P T K P P P PT P +PA
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/92 (27%), Positives = 32/92 (34%), Gaps = 2/92 (2%)
Query: 66 KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSK 125
KEP T+ + PT +K T T + + T P A E+
Sbjct: 513 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 572
Query: 126 PATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
P TPK P P P PT P +PA
Sbjct: 573 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604
Score = 37.7 bits (86), Expect = 0.023
Identities = 71/363 (19%), Positives = 118/363 (32%), Gaps = 49/363 (13%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTE 114
TTP++ KE T+ + PT +++ T E + TT+ P+
Sbjct: 598 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 657
Query: 115 QTEAVGGLSSKPATPKTTTP----PSSPPPTAVSPEFAYVPADPAQLAAQML------GK 164
T G + P P TTP P++P TA + P P + A + L G
Sbjct: 658 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 717
Query: 165 VSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVH 224
S+ + + A + P + A P S T++H
Sbjct: 718 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 777
Query: 225 -------VDLGSQPKENEAE--------PSTASSVPLQDEQEPPAYDQ--------APEV 261
+L ++P E P+T + + E A D+ PE
Sbjct: 778 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 837
Query: 262 TLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQS 321
T A T + + +T + Q PF ++ LK +
Sbjct: 838 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF--KITTLK----------T 885
Query: 322 PRVSPKSVVEK---TTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQP 378
++PK K TT+ + K E+ K N+K ++ + A TS K
Sbjct: 886 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 945
Query: 379 EVP 381
+P
Sbjct: 946 TMP 948
Score = 35.8 bits (81), Expect = 0.087
Identities = 30/109 (27%), Positives = 41/109 (37%), Gaps = 9/109 (8%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKS-TDTDEDNVTRTEYSDKTTQFPSVYAVPGT 113
TTP++ KEP T+ + PT + + T T E T T+ + T + PS
Sbjct: 408 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 467
Query: 114 EQTEAVGGLSSKPATPKTTTP-------PSSPPPTAVSPEFAYVPADPA 155
T + P P TTP P P PT P +PA
Sbjct: 468 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 8/108 (7%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT---QFPSVYAVP 111
TTP++ KEP T+ + PT ++ + T ++ T S TT P+ P
Sbjct: 252 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 311
Query: 112 GTEQTEAVGGLSSKPATPKTT----TPPSSPPPTAVSPEFAYVPADPA 155
+ ++K P TT T P P PT P +PA
Sbjct: 312 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 359
Score = 35.0 bits (79), Expect = 0.15
Identities = 27/103 (26%), Positives = 36/103 (34%), Gaps = 3/103 (2%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTE 114
TTP++ KEP T+ + PT ++ T T T P A E
Sbjct: 486 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 545
Query: 115 QTEAVGGLSSKPATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
+ P TP+ TP P P PT P +PA
Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 588
Score = 33.1 bits (74), Expect = 0.57
Identities = 61/323 (18%), Positives = 104/323 (32%), Gaps = 49/323 (15%)
Query: 66 KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSK 125
KEP T+ + PT +++ T T + P A T S+
Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652
Query: 126 PATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMP 185
P TTP + P T P P +PA + + P
Sbjct: 653 CDKPAPTTPKGTAPTTPKEPA-PTTPKEPAPTTPK---------------------GTAP 690
Query: 186 VVIKE-VPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASS- 243
+KE P++ AP G TS D + E P+T
Sbjct: 691 TTLKEPAPTTPKKPAPKELAPTTTKG---------PTSTTSDKPAPTTPKETAPTTPKEP 741
Query: 244 VPLQDEQEPPAYDQAP-----EVTLQADIEVMSTVHISSVYN--DVPVTEGVVYIEQLPE 296
P ++ P + P EV+ + +T+H S + ++ +E P+
Sbjct: 742 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 801
Query: 297 QIVIPFTDQVACLK----ENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEE 352
+ +P T A K + K E+ R +P +TT+ K + E+ +
Sbjct: 802 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-----ETTTAAPKMTKETATTTEKTT 856
Query: 353 NAKYSSVYMEAEATALLSDTSLK 375
+K ++ + +T T K
Sbjct: 857 ESKITATTTQVTSTTTQDTTPFK 879
Score = 32.3 bits (72), Expect = 0.96
Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 9/105 (8%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRT--EYSDKTTQFPSVYAVPG 112
TTP++ KEP T+ +S T E + T + T E + T + P+ P
Sbjct: 314 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PT 369
Query: 113 TEQTEAVGGLSSKPATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
T + A P TPK P P P PT P +PA
Sbjct: 370 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/91 (24%), Positives = 32/91 (35%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQ 115
TT + KEP T+ + PT ++ T T + P A T++
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506
Query: 116 TEAVGGLSSKPATPKTTTPPSSPPPTAVSPE 146
P TPK T P + T +PE
Sbjct: 507 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 537
Score = 31.6 bits (70), Expect = 1.6
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEKS--TDTDEDNVTRTEYSDKTTQFPSVYAVPGT 113
TT + KEP T+ + PT ++ T T E T T+ + T + P+ P T
Sbjct: 291 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA----PTT 346
Query: 114 EQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPE 146
+ A P TPK P + PT +P+
Sbjct: 347 PKKPA-------PTTPKEPAPTTPKEPTPTTPK 372
Score = 30.4 bits (67), Expect = 3.7
Identities = 36/153 (23%), Positives = 54/153 (35%), Gaps = 21/153 (13%)
Query: 70 KTSVESKVPTQMEKSTDTDEDNVT----RTEYSDKTT-----QFPSVYAVPGTE-QTEAV 119
+T+VE+K T K T TD T T+ +KT+ V A P + +T
Sbjct: 188 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 247
Query: 120 GGLSSKPATPKTTTP-------PSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQ 172
G + P P TTP P P PT + P P + A + +
Sbjct: 248 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS----APTTPKEPAPTTTKSAPTTPKEP 303
Query: 173 SDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAP 205
+ + A + P + E A +AP
Sbjct: 304 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 336
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 38.9 bits (89), Expect = 0.010
Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 16/112 (14%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEK---STDTDEDNVTRTEYSDKTTQFPSVYAVPG 112
TTP++ KEP T+ + PT +K +T + T E + TT+ PS P
Sbjct: 421 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS----PT 476
Query: 113 TEQTEAVGGLSSKPATPKTTTP---------PSSPPPTAVSPEFAYVPADPA 155
T + A S P T K P P P PT P +PA
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 528
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/92 (27%), Positives = 32/92 (34%), Gaps = 2/92 (2%)
Query: 66 KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSK 125
KEP T+ + PT +K T T + + T P A E+
Sbjct: 565 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 624
Query: 126 PATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
P TPK P P P PT P +PA
Sbjct: 625 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656
Score = 37.7 bits (86), Expect = 0.023
Identities = 71/363 (19%), Positives = 118/363 (32%), Gaps = 49/363 (13%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTE 114
TTP++ KE T+ + PT +++ T E + TT+ P+
Sbjct: 650 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 709
Query: 115 QTEAVGGLSSKPATPKTTTP----PSSPPPTAVSPEFAYVPADPAQLAAQML------GK 164
T G + P P TTP P++P TA + P P + A + L G
Sbjct: 710 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 769
Query: 165 VSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVH 224
S+ + + A + P + A P S T++H
Sbjct: 770 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 829
Query: 225 -------VDLGSQPKENEAE--------PSTASSVPLQDEQEPPAYDQ--------APEV 261
+L ++P E P+T + + E A D+ PE
Sbjct: 830 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 889
Query: 262 TLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQS 321
T A T + + +T + Q PF ++ LK +
Sbjct: 890 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF--KITTLK----------T 937
Query: 322 PRVSPKSVVEK---TTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQP 378
++PK K TT+ + K E+ K N+K ++ + A TS K
Sbjct: 938 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 997
Query: 379 EVP 381
+P
Sbjct: 998 TMP 1000
Score = 35.8 bits (81), Expect = 0.087
Identities = 30/109 (27%), Positives = 41/109 (37%), Gaps = 9/109 (8%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKS-TDTDEDNVTRTEYSDKTTQFPSVYAVPGT 113
TTP++ KEP T+ + PT + + T T E T T+ + T + PS
Sbjct: 460 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 519
Query: 114 EQTEAVGGLSSKPATPKTTTP-------PSSPPPTAVSPEFAYVPADPA 155
T + P P TTP P P PT P +PA
Sbjct: 520 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 568
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 8/108 (7%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT---QFPSVYAVP 111
TTP++ KEP T+ + PT ++ + T ++ T S TT P+ P
Sbjct: 304 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 363
Query: 112 GTEQTEAVGGLSSKPATPKTT----TPPSSPPPTAVSPEFAYVPADPA 155
+ ++K P TT T P P PT P +PA
Sbjct: 364 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 411
Score = 35.0 bits (79), Expect = 0.15
Identities = 27/103 (26%), Positives = 36/103 (34%), Gaps = 3/103 (2%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTE 114
TTP++ KEP T+ + PT ++ T T T P A E
Sbjct: 538 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 597
Query: 115 QTEAVGGLSSKPATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
+ P TP+ TP P P PT P +PA
Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 640
Score = 33.1 bits (74), Expect = 0.57
Identities = 61/323 (18%), Positives = 104/323 (32%), Gaps = 49/323 (15%)
Query: 66 KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSK 125
KEP T+ + PT +++ T T + P A T S+
Sbjct: 645 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704
Query: 126 PATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMP 185
P TTP + P T P P +PA + + P
Sbjct: 705 CDKPAPTTPKGTAPTTPKEPA-PTTPKEPAPTTPK---------------------GTAP 742
Query: 186 VVIKE-VPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASS- 243
+KE P++ AP G TS D + E P+T
Sbjct: 743 TTLKEPAPTTPKKPAPKELAPTTTKG---------PTSTTSDKPAPTTPKETAPTTPKEP 793
Query: 244 VPLQDEQEPPAYDQAP-----EVTLQADIEVMSTVHISSVYN--DVPVTEGVVYIEQLPE 296
P ++ P + P EV+ + +T+H S + ++ +E P+
Sbjct: 794 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 853
Query: 297 QIVIPFTDQVACLK----ENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEE 352
+ +P T A K + K E+ R +P +TT+ K + E+ +
Sbjct: 854 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-----ETTTAAPKMTKETATTTEKTT 908
Query: 353 NAKYSSVYMEAEATALLSDTSLK 375
+K ++ + +T T K
Sbjct: 909 ESKITATTTQVTSTTTQDTTPFK 931
Score = 32.3 bits (72), Expect = 0.96
Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 9/105 (8%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRT--EYSDKTTQFPSVYAVPG 112
TTP++ KEP T+ +S T E + T + T E + T + P+ P
Sbjct: 366 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PT 421
Query: 113 TEQTEAVGGLSSKPATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
T + A P TPK P P P PT P +PA
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/91 (24%), Positives = 32/91 (35%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQ 115
TT + KEP T+ + PT ++ T T + P A T++
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
Query: 116 TEAVGGLSSKPATPKTTTPPSSPPPTAVSPE 146
P TPK T P + T +PE
Sbjct: 559 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 589
Score = 31.6 bits (70), Expect = 1.6
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEKS--TDTDEDNVTRTEYSDKTTQFPSVYAVPGT 113
TT + KEP T+ + PT ++ T T E T T+ + T + P+ P T
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA----PTT 398
Query: 114 EQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPE 146
+ A P TPK P + PT +P+
Sbjct: 399 PKKPA-------PTTPKEPAPTTPKEPTPTTPK 424
Score = 30.4 bits (67), Expect = 3.7
Identities = 36/153 (23%), Positives = 54/153 (35%), Gaps = 21/153 (13%)
Query: 70 KTSVESKVPTQMEKSTDTDEDNVT----RTEYSDKTT-----QFPSVYAVPGTE-QTEAV 119
+T+VE+K T K T TD T T+ +KT+ V A P + +T
Sbjct: 240 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 299
Query: 120 GGLSSKPATPKTTTP-------PSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQ 172
G + P P TTP P P PT + P P + A + +
Sbjct: 300 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS----APTTPKEPAPTTTKSAPTTPKEP 355
Query: 173 SDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAP 205
+ + A + P + E A +AP
Sbjct: 356 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 388
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 38.9 bits (89), Expect = 0.010
Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 16/112 (14%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEK---STDTDEDNVTRTEYSDKTTQFPSVYAVPG 112
TTP++ KEP T+ + PT +K +T + T E + TT+ PS P
Sbjct: 462 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS----PT 517
Query: 113 TEQTEAVGGLSSKPATPKTTTP---------PSSPPPTAVSPEFAYVPADPA 155
T + A S P T K P P P PT P +PA
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 569
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/92 (27%), Positives = 32/92 (34%), Gaps = 2/92 (2%)
Query: 66 KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSK 125
KEP T+ + PT +K T T + + T P A E+
Sbjct: 606 KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 665
Query: 126 PATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
P TPK P P P PT P +PA
Sbjct: 666 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697
Score = 37.7 bits (86), Expect = 0.023
Identities = 71/363 (19%), Positives = 118/363 (32%), Gaps = 49/363 (13%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTE 114
TTP++ KE T+ + PT +++ T E + TT+ P+
Sbjct: 691 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 750
Query: 115 QTEAVGGLSSKPATPKTTTP----PSSPPPTAVSPEFAYVPADPAQLAAQML------GK 164
T G + P P TTP P++P TA + P P + A + L G
Sbjct: 751 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 810
Query: 165 VSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVH 224
S+ + + A + P + A P S T++H
Sbjct: 811 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 870
Query: 225 -------VDLGSQPKENEAE--------PSTASSVPLQDEQEPPAYDQ--------APEV 261
+L ++P E P+T + + E A D+ PE
Sbjct: 871 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 930
Query: 262 TLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQS 321
T A T + + +T + Q PF ++ LK +
Sbjct: 931 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPF--KITTLK----------T 978
Query: 322 PRVSPKSVVEK---TTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQP 378
++PK K TT+ + K E+ K N+K ++ + A TS K
Sbjct: 979 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 1038
Query: 379 EVP 381
+P
Sbjct: 1039 TMP 1041
Score = 35.8 bits (81), Expect = 0.087
Identities = 30/109 (27%), Positives = 41/109 (37%), Gaps = 9/109 (8%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKS-TDTDEDNVTRTEYSDKTTQFPSVYAVPGT 113
TTP++ KEP T+ + PT + + T T E T T+ + T + PS
Sbjct: 501 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 560
Query: 114 EQTEAVGGLSSKPATPKTTTP-------PSSPPPTAVSPEFAYVPADPA 155
T + P P TTP P P PT P +PA
Sbjct: 561 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 609
Score = 35.4 bits (80), Expect = 0.11
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 8/108 (7%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTT---QFPSVYAVP 111
TTP++ KEP T+ + PT ++ + T ++ T S TT P+ P
Sbjct: 345 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 404
Query: 112 GTEQTEAVGGLSSKPATPKTT----TPPSSPPPTAVSPEFAYVPADPA 155
+ ++K P TT T P P PT P +PA
Sbjct: 405 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 452
Score = 35.0 bits (79), Expect = 0.15
Identities = 27/103 (26%), Positives = 36/103 (34%), Gaps = 3/103 (2%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTE 114
TTP++ KEP T+ + PT ++ T T T P A E
Sbjct: 579 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 638
Query: 115 QTEAVGGLSSKPATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
+ P TP+ TP P P PT P +PA
Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 681
Score = 33.1 bits (74), Expect = 0.57
Identities = 61/323 (18%), Positives = 104/323 (32%), Gaps = 49/323 (15%)
Query: 66 KEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSK 125
KEP T+ + PT +++ T T + P A T S+
Sbjct: 686 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745
Query: 126 PATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMP 185
P TTP + P T P P +PA + + P
Sbjct: 746 CDKPAPTTPKGTAPTTPKEPA-PTTPKEPAPTTPK---------------------GTAP 783
Query: 186 VVIKE-VPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASS- 243
+KE P++ AP G TS D + E P+T
Sbjct: 784 TTLKEPAPTTPKKPAPKELAPTTTKG---------PTSTTSDKPAPTTPKETAPTTPKEP 834
Query: 244 VPLQDEQEPPAYDQAP-----EVTLQADIEVMSTVHISSVYN--DVPVTEGVVYIEQLPE 296
P ++ P + P EV+ + +T+H S + ++ +E P+
Sbjct: 835 APTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPK 894
Query: 297 QIVIPFTDQVACLK----ENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEE 352
+ +P T A K + K E+ R +P +TT+ K + E+ +
Sbjct: 895 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTP-----ETTTAAPKMTKETATTTEKTT 949
Query: 353 NAKYSSVYMEAEATALLSDTSLK 375
+K ++ + +T T K
Sbjct: 950 ESKITATTTQVTSTTTQDTTPFK 972
Score = 32.3 bits (72), Expect = 0.96
Identities = 30/105 (28%), Positives = 41/105 (39%), Gaps = 9/105 (8%)
Query: 56 TTPQKKLECL-KEPGKTSVESKVPTQMEKSTDTDEDNVTRT--EYSDKTTQFPSVYAVPG 112
TTP++ KEP T+ +S T E + T + T E + T + P+ P
Sbjct: 407 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PT 462
Query: 113 TEQTEAVGGLSSKPATPKTTTP--PSSPPPTAVSPEFAYVPADPA 155
T + A P TPK P P P PT P +PA
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/91 (24%), Positives = 32/91 (35%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQ 115
TT + KEP T+ + PT ++ T T + P A T++
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
Query: 116 TEAVGGLSSKPATPKTTTPPSSPPPTAVSPE 146
P TPK T P + T +PE
Sbjct: 600 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 630
Score = 31.6 bits (70), Expect = 1.6
Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 56 TTPQKKLECLKEPGKTSVESKVPTQMEKS--TDTDEDNVTRTEYSDKTTQFPSVYAVPGT 113
TT + KEP T+ + PT ++ T T E T T+ + T + P+ P T
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA----PTT 439
Query: 114 EQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPE 146
+ A P TPK P + PT +P+
Sbjct: 440 PKKPA-------PTTPKEPAPTTPKEPTPTTPK 465
Score = 30.4 bits (67), Expect = 3.7
Identities = 36/153 (23%), Positives = 54/153 (35%), Gaps = 21/153 (13%)
Query: 70 KTSVESKVPTQMEKSTDTDEDNVT----RTEYSDKTT-----QFPSVYAVPGTE-QTEAV 119
+T+VE+K T K T TD T T+ +KT+ V A P + +T
Sbjct: 281 ETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK 340
Query: 120 GGLSSKPATPKTTTP-------PSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQ 172
G + P P TTP P P PT + P P + A + +
Sbjct: 341 GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS----APTTPKEPAPTTTKSAPTTPKEP 396
Query: 173 SDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAP 205
+ + A + P + E A +AP
Sbjct: 397 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 429
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 38.9 bits (89), Expect = 0.010
Identities = 76/377 (20%), Positives = 124/377 (32%), Gaps = 24/377 (6%)
Query: 98 SDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQL 157
S TT FP +PG Q S P + TT P S +++ PE + P
Sbjct: 1728 STHTTAFPGSTTMPGVSQESTAS--HSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGST 1785
Query: 158 AAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQV 217
+L ++ V +T P S + S K
Sbjct: 1786 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1845
Query: 218 VNQTSVHVDLGS----QPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMST- 272
TS V+L + P +ASS L +E +P T ST
Sbjct: 1846 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 1905
Query: 273 ---VHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSV 329
V S+ Y+ P G PE + + + + SP + ++
Sbjct: 1906 SGLVEESTAYHSSP---GSTQTMHFPESSTASGRSEES-RTSHSSTTHTISSPPSTTSAL 1961
Query: 330 VEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEG 389
VE+ TS S S S +++ S E+TA S G +PA+ +
Sbjct: 1962 VEEPTSYHS--SPGSTATTHFPDSSTTSG--RSEESTASHSSQDATGTIVLPAR---STT 2014
Query: 390 AIKIGSEKSLHL---EVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTS 446
++ +G + + +E T++ T S +++ P + A SG S
Sbjct: 2015 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 2074
Query: 447 VKSSSGPFPPAPEGLTA 463
+S++ P TA
Sbjct: 2075 EESTTSHSRPGSTHTTA 2091
Score = 38.1 bits (87), Expect = 0.018
Identities = 72/377 (19%), Positives = 119/377 (31%), Gaps = 24/377 (6%)
Query: 98 SDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQL 157
S TT FP +PG Q S P + TT P S +++ PE + P
Sbjct: 3285 STHTTAFPGSTTMPGVSQESTAS--HSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGST 3342
Query: 158 AAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQV 217
+L ++ V +T P S + + K
Sbjct: 3343 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 3402
Query: 218 VNQTSVHVDLGS----QPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMST- 272
TS V+L + P +ASS L +E +P T ST
Sbjct: 3403 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 3462
Query: 273 ---VHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSV 329
V S+ Y+ P G PE + + + + +P + V
Sbjct: 3463 SGLVEESTTYHSSP---GSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALV 3519
Query: 330 VEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEG 389
E T+ S S + + S E+TA S G +PA+ +
Sbjct: 3520 EEPTSYHSSPGSTATTHFPDSSTTSGRSE-----ESTASHSSQDATGTIVLPAR---STT 3571
Query: 390 AIKIGSEKSLHL---EVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTS 446
++ +G + + +E T++ T S +++ P + A SG S
Sbjct: 3572 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 3631
Query: 447 VKSSSGPFPPAPEGLTA 463
+S++ P TA
Sbjct: 3632 EESTTSHSRPGSTHTTA 3648
Score = 35.0 bits (79), Expect = 0.15
Identities = 79/367 (21%), Positives = 125/367 (34%), Gaps = 83/367 (22%)
Query: 101 TTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQ 160
TT FPS +PG Q S P + TT P S +++ PE + P
Sbjct: 4371 TTAFPSSTTMPGVSQESTAS--HSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETT 4428
Query: 161 MLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQ 220
+L P + A ++ A+ V S +
Sbjct: 4429 LL-----------------------------PDNTTASGLLEASTPVHS---------ST 4450
Query: 221 TSVHVDL---GSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISS 277
S H L GS ++ E+ +T S P + P AP T A +E+ +T H S
Sbjct: 4451 GSPHTTLSPAGSTTRQGES--TTFQSWPNSKDTTP-----APPTTTSAFVELSTTSHGSP 4503
Query: 278 VYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSP--RVSPKSVVEKTTS 335
+ P T F+ L +E+S SP + S TTS
Sbjct: 4504 --SSTPTTH---------------FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS 4546
Query: 336 GMSKKSVE------SVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEG 389
G+ ++S S + E+ S E+ + + ++ P + L++
Sbjct: 4547 GLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT 4606
Query: 390 AI--KIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSV 447
+ GS + H T+ + EES + Q+ G VL + +V G S
Sbjct: 4607 SYHSSPGSTATTHFPDSSTT----SGRSEESTASHSSQDATGTIVLPARSTTSVLLGEST 4662
Query: 448 KS--SSG 452
S SSG
Sbjct: 4663 TSPISSG 4669
Score = 33.9 bits (76), Expect = 0.33
Identities = 81/413 (19%), Positives = 132/413 (31%), Gaps = 81/413 (19%)
Query: 77 VPTQMEKSTDTDEDNVTRTEY-SDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPP 135
+P M S ++E + + S TT FP +PG Q S P TT P
Sbjct: 651 LPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTAS--HSSPGPTDTTLSP 708
Query: 136 SSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSE 195
S +++ PE+ + P +L P +
Sbjct: 709 GSTTASSLGPEYTTFHSRPGSTETTLL-----------------------------PDNT 739
Query: 196 AAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDL---GSQPKENEAEPSTASSVPLQDEQEP 252
A ++ A+ V S + S H L GS ++ E+ +T S P + P
Sbjct: 740 TASGLLEASMPVHS---------STRSPHTTLSPAGSTTRQGES--TTFHSWPSSKDTRP 788
Query: 253 PAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVV------YIEQLPEQIVIPFTDQV 306
AP T A +E +T H S + +P T +E+ P + Q
Sbjct: 789 -----APPTTTSAFVEPSTTSHGSP--SSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 841
Query: 307 ACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEAT 366
E++ + + S S +S S S A +EE Y S T
Sbjct: 842 MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTS------ALVEEPTSYHSSPGSTATT 895
Query: 367 ALLSDTSLKGQPE---VPAQLLDAEGAIKIGSEKSLHL-------------EVEITSIVS 410
++ G+ E DA G I + + + + +E T++
Sbjct: 896 HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 955
Query: 411 DNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTA 463
T S ++ P + A SG S +S++ P TA
Sbjct: 956 STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTA 1008
Score = 30.4 bits (67), Expect = 3.7
Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 5/105 (4%)
Query: 53 SEGTTP--QKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEY-SDKTTQFPSVYA 109
S TTP K L ++ ++ P M S+ + E ++ S TT FP+
Sbjct: 4870 STATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTT 4929
Query: 110 VPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADP 154
G Q SKP + +TT P S ++ + EF + P
Sbjct: 4930 TSGLSQESTT--FHSKPGSTETTLSPGSITTSSFAQEFTTPHSQP 4972
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 38.9 bits (89), Expect = 0.010
Identities = 68/327 (20%), Positives = 122/327 (37%), Gaps = 55/327 (16%)
Query: 51 KWSEGTTPQKKLECLKEPGKT--SVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVY 108
K SE T K+ + K P +T S + +P EK+ E N+ ++ S K Q P +
Sbjct: 39 KSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKS--SAKPIQ-PKLG 95
Query: 109 AVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPT--------------AVSPEFAYVPADP 154
+P S KP+ PK P +P T A+ P+ +P
Sbjct: 96 NIPKA---------SVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSS 146
Query: 155 AQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIK----EVPSSEAAEDVMVAAPLVCSG 210
A+ LG ++ S D+ S I+ ++P S S
Sbjct: 147 AKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKS--------------SA 192
Query: 211 KVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVM 270
K ++ ++ N V SQPKE + S ++ ++ P + ++A + + DI
Sbjct: 193 KPIQPKLGNIPKASVK-PSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQ-PKEGDIPKS 250
Query: 271 STVHISSVYNDVPVT-EGVVY-----IEQLPEQIVIPFTDQVACLKENEQSKENEQSPRV 324
I D+P + E + I + PE+ + P + E + P+
Sbjct: 251 PEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPK- 309
Query: 325 SPKSVVEKTTSGMSKKSVESVKLAQLE 351
SPK ++ + K E++ +++
Sbjct: 310 SPKQAIQPKEGDIPKSLEEAIPPKEID 336
Score = 36.2 bits (82), Expect = 0.067
Identities = 63/272 (23%), Positives = 103/272 (37%), Gaps = 35/272 (12%)
Query: 76 KVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPP 135
K P + +S D + K P A P + + S KP+ PK + P
Sbjct: 114 KAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIP 173
Query: 136 SSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVI--KEVPS 193
SP T + P+ +P A+ LG + S D++ S I KE
Sbjct: 174 KSPEET-IQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDL 232
Query: 194 SEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKE-NEAEPSTASSVPLQDEQ-- 250
++ E+ + K ++ + ++ G PK EA +P E+
Sbjct: 233 PKSLEEAI-------QPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETI 285
Query: 251 EPPAYD--QAPEVTLQ---ADIEVMSTVHISSVYNDVPVTEGVVYIEQL--PEQIVIPFT 303
+P D ++PE +Q DI I D+P + +E+ P++I IP +
Sbjct: 286 QPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKS-----LEEAIPPKEIDIPKS 340
Query: 304 DQVACLKENEQSKENEQSPRVSPKSVVEKTTS 335
+ E Q KE++ SPKS+ E T S
Sbjct: 341 PE-----ETIQPKEDD-----SPKSLEEATPS 362
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 38.9 bits (89), Expect = 0.010
Identities = 68/327 (20%), Positives = 122/327 (37%), Gaps = 55/327 (16%)
Query: 51 KWSEGTTPQKKLECLKEPGKT--SVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVY 108
K SE T K+ + K P +T S + +P EK+ E N+ ++ S K Q P +
Sbjct: 106 KSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKS--SAKPIQ-PKLG 162
Query: 109 AVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPT--------------AVSPEFAYVPADP 154
+P S KP+ PK P +P T A+ P+ +P
Sbjct: 163 NIPKA---------SVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSS 213
Query: 155 AQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIK----EVPSSEAAEDVMVAAPLVCSG 210
A+ LG ++ S D+ S I+ ++P S S
Sbjct: 214 AKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKS--------------SA 259
Query: 211 KVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVM 270
K ++ ++ N V SQPKE + S ++ ++ P + ++A + + DI
Sbjct: 260 KPIQPKLGNIPKASVK-PSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQ-PKEGDIPKS 317
Query: 271 STVHISSVYNDVPVT-EGVVY-----IEQLPEQIVIPFTDQVACLKENEQSKENEQSPRV 324
I D+P + E + I + PE+ + P + E + P+
Sbjct: 318 PEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPK- 376
Query: 325 SPKSVVEKTTSGMSKKSVESVKLAQLE 351
SPK ++ + K E++ +++
Sbjct: 377 SPKQAIQPKEGDIPKSLEEAIPPKEID 403
Score = 36.2 bits (82), Expect = 0.067
Identities = 63/272 (23%), Positives = 103/272 (37%), Gaps = 35/272 (12%)
Query: 76 KVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPP 135
K P + +S D + K P A P + + S KP+ PK + P
Sbjct: 181 KAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIP 240
Query: 136 SSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVI--KEVPS 193
SP T + P+ +P A+ LG + S D++ S I KE
Sbjct: 241 KSPEET-IQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDL 299
Query: 194 SEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKE-NEAEPSTASSVPLQDEQ-- 250
++ E+ + K ++ + ++ G PK EA +P E+
Sbjct: 300 PKSLEEAI-------QPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETI 352
Query: 251 EPPAYD--QAPEVTLQ---ADIEVMSTVHISSVYNDVPVTEGVVYIEQL--PEQIVIPFT 303
+P D ++PE +Q DI I D+P + +E+ P++I IP +
Sbjct: 353 QPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKS-----LEEAIPPKEIDIPKS 407
Query: 304 DQVACLKENEQSKENEQSPRVSPKSVVEKTTS 335
+ E Q KE++ SPKS+ E T S
Sbjct: 408 PE-----ETIQPKEDD-----SPKSLEEATPS 429
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 38.9 bits (89), Expect = 0.010
Identities = 68/327 (20%), Positives = 122/327 (37%), Gaps = 55/327 (16%)
Query: 51 KWSEGTTPQKKLECLKEPGKT--SVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVY 108
K SE T K+ + K P +T S + +P EK+ E N+ ++ S K Q P +
Sbjct: 39 KSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKS--SAKPIQ-PKLG 95
Query: 109 AVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPT--------------AVSPEFAYVPADP 154
+P S KP+ PK P +P T A+ P+ +P
Sbjct: 96 NIPKA---------SVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSS 146
Query: 155 AQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIK----EVPSSEAAEDVMVAAPLVCSG 210
A+ LG ++ S D+ S I+ ++P S S
Sbjct: 147 AKPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKS--------------SA 192
Query: 211 KVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVM 270
K ++ ++ N V SQPKE + S ++ ++ P + ++A + + DI
Sbjct: 193 KPIQPKLGNIPKASVK-PSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQ-PKEGDIPKS 250
Query: 271 STVHISSVYNDVPVT-EGVVY-----IEQLPEQIVIPFTDQVACLKENEQSKENEQSPRV 324
I D+P + E + I + PE+ + P + E + P+
Sbjct: 251 PEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPKEGDIPK- 309
Query: 325 SPKSVVEKTTSGMSKKSVESVKLAQLE 351
SPK ++ + K E++ +++
Sbjct: 310 SPKQAIQPKEGDIPKSLEEAIPPKEID 336
Score = 36.2 bits (82), Expect = 0.067
Identities = 63/272 (23%), Positives = 103/272 (37%), Gaps = 35/272 (12%)
Query: 76 KVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPP 135
K P + +S D + K P A P + + S KP+ PK + P
Sbjct: 114 KAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESDIP 173
Query: 136 SSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVI--KEVPS 193
SP T + P+ +P A+ LG + S D++ S I KE
Sbjct: 174 KSPEET-IQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDL 232
Query: 194 SEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKE-NEAEPSTASSVPLQDEQ-- 250
++ E+ + K ++ + ++ G PK EA +P E+
Sbjct: 233 PKSLEEAI-------QPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETI 285
Query: 251 EPPAYD--QAPEVTLQ---ADIEVMSTVHISSVYNDVPVTEGVVYIEQL--PEQIVIPFT 303
+P D ++PE +Q DI I D+P + +E+ P++I IP +
Sbjct: 286 QPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKS-----LEEAIPPKEIDIPKS 340
Query: 304 DQVACLKENEQSKENEQSPRVSPKSVVEKTTS 335
+ E Q KE++ SPKS+ E T S
Sbjct: 341 PE-----ETIQPKEDD-----SPKSLEEATPS 362
>gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]
Length = 1460
Score = 38.5 bits (88), Expect = 0.013
Identities = 84/396 (21%), Positives = 147/396 (37%), Gaps = 64/396 (16%)
Query: 112 GTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVS----PEFAYVPADPAQLAAQMLGKVSS 167
GT+ A+ +++ PA K T PS+ PTA S P+ +P+ P Q+ K+
Sbjct: 255 GTKSMAALTVMAAAPAGMKGITQPSAFIPTAESNSFQPQVKTLPS-PIDAKQQLQRKIQK 313
Query: 168 IHSDQ--------------SDVLMVDVATSMP-------------VVIKEVPSSEAAEDV 200
+Q S+ + T++P +V+ VPS +
Sbjct: 314 KQQEQKLQSPLPGESAAKKSESATSNGVTNLPNGNPSILSPQPIGIVVAAVPSPIPVQRT 373
Query: 201 --MVAAPLVCS---GKV--LEVQVVNQTSVHVDLGSQPKEN-EAEPSTASSVPLQDEQEP 252
+V +P S GKV L VQVV Q V + +N A P S + Q
Sbjct: 374 RQLVTSPSPMSSSDGKVLPLNVQVVTQHMQSVKQAPKTPQNVPASPGGDRSARHRYPQIL 433
Query: 253 PAYDQAPEVTLQADIEVMST-----------VHISSVYNDVPVTEGVVYIEQLPEQIVIP 301
P +T+++ V+ T H+SS+ N V +T I P P
Sbjct: 434 PKPANTSALTIRSPTTVLFTSSPIKTAVVPASHMSSL-NVVKMTT----ISLTPSNSNTP 488
Query: 302 FTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYM 361
+ ++E+ P++ SVV + G S +++ + SS
Sbjct: 489 LKHSASVSSATGTTEESRSVPQIKNGSVVSLQSPGSRSSSAGGTSAVEVKVEPETSS--- 545
Query: 362 EAEATALLSDTSLKGQPEVPAQLL----DAEGAIKIGSEKSLHLEVEITSIVSDNTGQEE 417
+ ++ P+ P+ LL + +GA++ S + + +E++ T + T +
Sbjct: 546 DEHPVQCQENSDEAKAPQTPSALLGQKSNTDGALQKPSNEGV-IEIKATKVCDQRTKCKS 604
Query: 418 SGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGP 453
+P G + + A + T SSS P
Sbjct: 605 RCNEMLPGTSTGNNQSTITLSVASQNLTFTSSSSPP 640
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 38.1 bits (87), Expect = 0.018
Identities = 64/273 (23%), Positives = 109/273 (39%), Gaps = 46/273 (16%)
Query: 231 PKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVY 290
P + +P + P Q P+Y Q P+ ++ S+ Y+ P
Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ---SQPPQLQSS---QPPYSQQP------- 522
Query: 291 IEQLP-EQIVIPFTDQVACLKENEQSKE-----------NEQSPRVSPKSVVEKTTSGMS 338
Q P +Q P+ Q + +++ QS+ +Q P+ S + + +
Sbjct: 523 -SQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQ 581
Query: 339 KKSVESVKLAQLEEN----AKYSSVYMEAEATALLSDTSLKGQPE--------VPAQLLD 386
+S +S + A ++ + S ++A++ S TS KG E P+ L D
Sbjct: 582 PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD 641
Query: 387 AEGAI---KIGSEKSLHLEVEITSIVSDNTGQEESGENS--VPQEMEGKPVLSGEAAEAV 441
G+I +G+E +L V TS +S + G++ + S P P + G + V
Sbjct: 642 LSGSIDDLPMGTEGALSPGVS-TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPV 700
Query: 442 HSGTSV-KSSSGPFPPAP-EGLTAPEIEPEGES 472
S SV +S SGP PA G P P G+S
Sbjct: 701 GSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQS 733
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 38.1 bits (87), Expect = 0.018
Identities = 64/273 (23%), Positives = 109/273 (39%), Gaps = 46/273 (16%)
Query: 231 PKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVY 290
P + +P + P Q P+Y Q P+ ++ S+ Y+ P
Sbjct: 476 PHPQQQQPPYSQQPPSQTPHAQPSYQQQPQ---SQPPQLQSS---QPPYSQQP------- 522
Query: 291 IEQLP-EQIVIPFTDQVACLKENEQSKE-----------NEQSPRVSPKSVVEKTTSGMS 338
Q P +Q P+ Q + +++ QS+ +Q P+ S + + +
Sbjct: 523 -SQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQ 581
Query: 339 KKSVESVKLAQLEEN----AKYSSVYMEAEATALLSDTSLKGQPE--------VPAQLLD 386
+S +S + A ++ + S ++A++ S TS KG E P+ L D
Sbjct: 582 PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD 641
Query: 387 AEGAI---KIGSEKSLHLEVEITSIVSDNTGQEESGENS--VPQEMEGKPVLSGEAAEAV 441
G+I +G+E +L V TS +S + G++ + S P P + G + V
Sbjct: 642 LSGSIDDLPMGTEGALSPGVS-TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPV 700
Query: 442 HSGTSV-KSSSGPFPPAP-EGLTAPEIEPEGES 472
S SV +S SGP PA G P P G+S
Sbjct: 701 GSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQS 733
>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
Length = 699
Score = 37.7 bits (86), Expect = 0.023
Identities = 59/263 (22%), Positives = 105/263 (39%), Gaps = 66/263 (25%)
Query: 220 QTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQA---------DIEVM 270
+TSV+++LGS E+ +T SV Q+ + E++L + + +V
Sbjct: 175 KTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVT 234
Query: 271 STVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVV 330
+T H ND+ TE E+ PE+ + + A E+E S V
Sbjct: 235 NTEHHQPSNNDLNTTEKRA-AERHPEK----YQGEAASGCESETS--------------V 275
Query: 331 EKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGA 390
+ SG+S +S + Q + +++ + ++ E L + +L+ G+
Sbjct: 276 SEDCSGLSSQS--DILTTQQRDTMQHNLIKLQQEMAELEA-------------VLEQHGS 320
Query: 391 IKIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSS 450
S SI+SD++ E+ P++ + VL TS KSS
Sbjct: 321 QPSNS---------YPSIISDSSALEDLRN---PEQSTSEKVL-----------TSQKSS 357
Query: 451 SGPFPPAPEGLTAPEIEPEGEST 473
P PEGL+A + E +S+
Sbjct: 358 EYPISQNPEGLSADKFEVSADSS 380
>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
Length = 759
Score = 37.7 bits (86), Expect = 0.023
Identities = 59/263 (22%), Positives = 105/263 (39%), Gaps = 66/263 (25%)
Query: 220 QTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQA---------DIEVM 270
+TSV+++LGS E+ +T SV Q+ + E++L + + +V
Sbjct: 175 KTSVYIELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVT 234
Query: 271 STVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVV 330
+T H ND+ TE E+ PE+ + + A E+E S V
Sbjct: 235 NTEHHQPSNNDLNTTEKRA-AERHPEK----YQGEAASGCESETS--------------V 275
Query: 331 EKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGA 390
+ SG+S +S + Q + +++ + ++ E L + +L+ G+
Sbjct: 276 SEDCSGLSSQS--DILTTQQRDTMQHNLIKLQQEMAELEA-------------VLEQHGS 320
Query: 391 IKIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSS 450
S SI+SD++ E+ P++ + VL TS KSS
Sbjct: 321 QPSNS---------YPSIISDSSALEDLRN---PEQSTSEKVL-----------TSQKSS 357
Query: 451 SGPFPPAPEGLTAPEIEPEGEST 473
P PEGL+A + E +S+
Sbjct: 358 EYPISQNPEGLSADKFEVSADSS 380
>gi|11641239 hypothetical protein LOC53838 [Homo sapiens]
Length = 449
Score = 37.7 bits (86), Expect = 0.023
Identities = 46/170 (27%), Positives = 67/170 (39%), Gaps = 20/170 (11%)
Query: 98 SDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPA-- 155
S Q P A+P +T + L+++ T TT SSP T SP ++P+D A
Sbjct: 189 STALAQVPKSSALP---RTATLATLATRAQTVATTANTSSPMSTRPSPS-KHMPSDTAAS 244
Query: 156 ---QLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKV 212
+ Q G +S + DQ V + +T MP P+ P V +
Sbjct: 245 PVPPMRPQAQGPISQVSVDQPVVNTTNKSTPMPSNTTPEPA---------PTPTVVTTTK 295
Query: 213 LEVQVVNQTSVHVDLGSQPKENEA-EPST-ASSVPLQDEQEPPAYDQAPE 260
+ + + V V S E EA P+T S +P P QAPE
Sbjct: 296 AQAREPTASPVPVPHTSPIPEMEAMSPTTQPSPMPYTQRAAGPGTSQAPE 345
Score = 32.0 bits (71), Expect = 1.3
Identities = 46/207 (22%), Positives = 74/207 (35%), Gaps = 15/207 (7%)
Query: 76 KVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQ--TEAVGGL---SSKPATPK 130
+V T+ TD E + T+ P+ A T T A + SS P T
Sbjct: 78 EVTTEDTSRTDVSEPATSGGAADGVTSIAPTAVASSTTAASITTAASSMTVASSAPTTAA 137
Query: 131 TTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKE 190
++T +S PT + + P LA L +S + ++ S+ + +
Sbjct: 138 SSTTVASIAPTTAASSMTAASSTPMTLA---LPAPTSTSTGRTPSTTATGHPSLSTALAQ 194
Query: 191 VPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQ 250
VP S A A L + V TS + P ++ + AS VP Q
Sbjct: 195 VPKSSALPRTATLATLATRAQT--VATTANTSSPMSTRPSPSKHMPSDTAASPVPPMRPQ 252
Query: 251 EPPAYDQAPEVTLQADIEVMSTVHISS 277
Q P + D V++T + S+
Sbjct: 253 A-----QGPISQVSVDQPVVNTTNKST 274
>gi|37595548 phosphoinositol 3-phosphate-binding protein-3 [Homo
sapiens]
Length = 1048
Score = 37.7 bits (86), Expect = 0.023
Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Query: 59 QKKLECLKEP-GKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTE 117
QKK+E +K K+S+++ VP S D +D+ ++ + +K + A TE +
Sbjct: 948 QKKVERIKTLIAKSSMQNVVPIGEGDSVDVPQDSESQLQEQEKRIEISCALA---TEASR 1004
Query: 118 AVGGLSSKPATPKTTTPPSSPPPTA 142
LS + ATP T P+SP P A
Sbjct: 1005 RGRMLSVQCATPSPPTSPASPAPPA 1029
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 37.4 bits (85), Expect = 0.030
Identities = 89/448 (19%), Positives = 145/448 (32%), Gaps = 37/448 (8%)
Query: 37 AAAYFQELTMYRVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTE 96
AAA E + + QKK K + +K P + KS+D+D D+ + E
Sbjct: 119 AAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDE 178
Query: 97 YSDKTTQFPSVYAVPGTEQTEA-------------------VGGLSSKPATPKTTTPPSS 137
Q P + V QT+A SS ++ + ++
Sbjct: 179 --PPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAA 236
Query: 138 PPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSD--VLMVDVATSMPVVIKEVPSSE 195
P P+ V P + A K SS SD + P VP
Sbjct: 237 ATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPS 296
Query: 196 AAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAY 255
A V + Q V + D E E +P T + V + PPA
Sbjct: 297 APPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAK 356
Query: 256 DQAPEVTLQADIE----------VMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQ 305
A + +D + T SS V V P+Q + +
Sbjct: 357 KAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQ-PVGGGQK 415
Query: 306 VACLKENEQSKENE--QSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEA 363
+ K + S E E S K +V T + K+ S+ Q + ++ SS ++
Sbjct: 416 LLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDS 475
Query: 364 EATALLSD-TSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGENS 422
++ + TS + P ++ K S K E +S D++ +EE
Sbjct: 476 SSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKG 535
Query: 423 VPQEMEGKPVLSGEAAEAVHSGTSVKSS 450
P +G +A +G + K+S
Sbjct: 536 KGSPRPQAPKANGTSALTAQNGKAAKNS 563
Score = 35.4 bits (80), Expect = 0.11
Identities = 87/419 (20%), Positives = 154/419 (36%), Gaps = 65/419 (15%)
Query: 68 PGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDK--TTQFPSVYAVP-GTEQTEAVGGLSS 124
PGK + ++ + E+S+D D++ + + K Q + A P + +++ SS
Sbjct: 116 PGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSS 175
Query: 125 KPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQML-GKV-----SSIHSDQSDVLMV 178
+ PK P +P + P PA+ A ++ GK SS S SD
Sbjct: 176 EDEPPKNQKPKITPVTVKAQTK---APPKPARAAPKIANGKAASSSSSSSSSSSSDDSEE 232
Query: 179 DVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEP 238
+ A + P K VP + V+ AP+ + ++ S + Q K + +P
Sbjct: 233 EKAAATPK--KTVPKKQ----VVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286
Query: 239 STASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQI 298
SSVP PP + +E V S +D
Sbjct: 287 GPYSSVP--PPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSD----------------- 327
Query: 299 VIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTS--GMSKKSVESVKLAQLEENAKY 356
E++ S E E+ P K+VV K T+ +KK+ ES + ++++
Sbjct: 328 ------------ESDSSSEEEKKP--PTKAVVSKATTKPPPAKKAAESSSDSSDSDSSED 373
Query: 357 SSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQE 416
+ T S + PA A +G + L +T ++ +E
Sbjct: 374 DEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKL-----LTRKADSSSSEE 428
Query: 417 ESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE 475
ES S +E + K +++ +A T+ + S P AP+G + + S+ E
Sbjct: 429 ES---SSSEEEKTKKMVATTKPKA----TAKAALSLPAKQAPQGSRDSSSDSDSSSSEE 480
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.122 0.326
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,442,544
Number of Sequences: 37866
Number of extensions: 965029
Number of successful extensions: 6216
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 274
Number of HSP's that attempted gapping in prelim test: 5220
Number of HSP's gapped (non-prelim): 1157
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.