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Search of human proteins with 24497519
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo
sapiens]
(653 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens] 1331 0.0
gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens] 790 0.0
gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens] 661 0.0
gi|218749883 alpha 1,2-mannosidase [Homo sapiens] 327 2e-89
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [... 191 2e-48
gi|222537737 ER degradation enhancer, mannosidase alpha-like 2 i... 186 4e-47
gi|222537739 ER degradation enhancer, mannosidase alpha-like 2 i... 166 8e-41
gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Ho... 164 2e-40
gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C) ... 36 0.13
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 35 0.28
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 35 0.28
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 35 0.28
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 35 0.28
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 34 0.37
gi|119220564 one cut domain, family member 2 [Homo sapiens] 34 0.37
gi|4502565 calpain, small subunit 1 [Homo sapiens] 34 0.48
gi|51599151 calpain, small subunit 1 [Homo sapiens] 34 0.48
gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 34 0.48
gi|223633890 hypothetical protein LOC729956 [Homo sapiens] 33 0.63
gi|169205008 PREDICTED: hypothetical protein [Homo sapiens] 33 1.1
gi|169205607 PREDICTED: hypothetical protein [Homo sapiens] 33 1.1
gi|169204476 PREDICTED: hypothetical protein [Homo sapiens] 33 1.1
gi|55749424 transcription elongation factor A (SII)-like 1 [Homo... 33 1.1
gi|55749406 transcription elongation factor A (SII)-like 1 [Homo... 33 1.1
gi|55749397 transcription elongation factor A (SII)-like 1 [Homo... 33 1.1
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 33 1.1
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 32 1.4
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 32 1.8
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 32 1.8
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 32 1.8
>gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]
Length = 653
Score = 1331 bits (3444), Expect = 0.0
Identities = 653/653 (100%), Positives = 653/653 (100%)
Query: 1 MPVGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIF 60
MPVGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIF
Sbjct: 1 MPVGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIF 60
Query: 61 FLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALEDN 120
FLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALEDN
Sbjct: 61 FLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALEDN 120
Query: 121 LARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPI 180
LARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPI
Sbjct: 121 LARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPI 180
Query: 181 GVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGAT 240
GVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGAT
Sbjct: 181 GVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGAT 240
Query: 241 IVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEI 300
IVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEI
Sbjct: 241 IVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEI 300
Query: 301 FRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHL 360
FRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHL
Sbjct: 301 FRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHL 360
Query: 361 SHLSGNPIFAEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLL 420
SHLSGNPIFAEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLL
Sbjct: 361 SHLSGNPIFAEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLL 420
Query: 421 KAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGG 480
KAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGG
Sbjct: 421 KAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGG 480
Query: 481 MFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEK 540
MFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEK
Sbjct: 481 MFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEK 540
Query: 541 YYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDD 600
YYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDD
Sbjct: 541 YYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDD 600
Query: 601 VQQSFFLAETLKYLYLIFSDDDLLPLEHWIFNSEAHLLPILPKDKKEVEIREE 653
VQQSFFLAETLKYLYLIFSDDDLLPLEHWIFNSEAHLLPILPKDKKEVEIREE
Sbjct: 601 VQQSFFLAETLKYLYLIFSDDDLLPLEHWIFNSEAHLLPILPKDKKEVEIREE 653
>gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens]
Length = 641
Score = 790 bits (2041), Expect = 0.0
Identities = 390/613 (63%), Positives = 478/613 (77%), Gaps = 19/613 (3%)
Query: 34 AALRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSSPALQPAADHKPG---P 90
A LRL+EKF+LLL+ SAFITLCFGA FFLPDSSK L L P D G P
Sbjct: 29 ATLRLSEKFILLLILSAFITLCFGAFFFLPDSSKHKRFDL-GLEDVLIPHVDAGKGAKNP 87
Query: 91 GARAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRDI 150
G + R EE E +IR +HE+AL EAKE L+K EEI+ +I
Sbjct: 88 GVFLIHGPDEHRHREEE----------ERLRNKIRADHEKALEEAKEKLRKSREEIRAEI 137
Query: 151 LLEKKKVAQD-QLRDKAPFRGLPPVDFVPPIGVESREPADAAIREKRAKIKEMMKHAWNN 209
EK KV Q+ ++++ P LPPV +G+ +P D IREKR KIKEMMKHAW+N
Sbjct: 138 QTEKNKVVQEMKIKENKP---LPPVPIPNLVGIRGGDPEDNDIREKREKIKEMMKHAWDN 194
Query: 210 YKGYAWGLNELKPISKGGHSSSLFGNIK-GATIVDALDTLFIMEMKHEFEEAKSWVEENL 268
Y+ Y WG NEL+PI++ GHS ++FG+ + GATIVDALDTL+IM + EF + + W+E+NL
Sbjct: 195 YRTYGWGHNELRPIARKGHSPNIFGSSQMGATIVDALDTLYIMGLHDEFLDGQRWIEDNL 254
Query: 269 DFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPAFHTPSGIPWALLN 328
DF+VN+E+SVFEVNIRF+GGLL+AYYLSGEEIF+ KAV+L KLLPAF+TP+GIPWA++N
Sbjct: 255 DFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKIKAVQLAEKLLPAFNTPTGIPWAMVN 314
Query: 329 MKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGNPIFAEKVMNIRTVLNKLEKPQG 388
+KSG+GRNW WAS GSSILAEFGTLH+EF+HLS+L+G+ + +KVM+IR +L K+++P G
Sbjct: 315 LKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMDRPNG 374
Query: 389 LYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKTDLEAKKMYFDAVQAIETHL 448
LYPNYLNP +G+WGQ+H SVGGLGDSFYEYLLKAWLMSDKTD EA+KMY DA++AIE HL
Sbjct: 375 LYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHL 434
Query: 449 IRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIARTC 508
I+KS GLT+I EWK G LE KMGHL CFAGGMFALGAD + A HYLELGAEIARTC
Sbjct: 435 IKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELGAEIARTC 494
Query: 509 HESYNRTFMKLGPEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKWA 568
HESY+RT +KLGPE+F+FDG VEA+A RQ EKYYILRPEV+ETY Y+WR THDP+YR+W
Sbjct: 495 HESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWG 554
Query: 569 WEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDDLLPLEH 628
WEA A+E +CRVNGG+SG++DVY ++DDVQQSFFLAETLKYLYL+FS DDLLPL+H
Sbjct: 555 WEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDLLPLDH 614
Query: 629 WIFNSEAHLLPIL 641
W+FN+EAH LP+L
Sbjct: 615 WVFNTEAHPLPVL 627
>gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens]
Length = 630
Score = 661 bits (1705), Expect = 0.0
Identities = 337/622 (54%), Positives = 438/622 (70%), Gaps = 20/622 (3%)
Query: 31 SGPAALRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSSPALQPAADHKPGP 90
+ P LRL +KF+ LL S +TLCFGA+F LP SS+L L +P Q +PG
Sbjct: 12 ASPWGLRLPQKFLFLLFLSGLVTLCFGALFLLPHSSRLKRLFL---APRTQ-----QPGL 63
Query: 91 GARAEDAAEGRARRRE---EGAPGDPEAALEDNLARIRENHERA-LREAKETLQKLPEEI 146
AE A AR +E AP P +D + + LR + T +
Sbjct: 64 EVVAEIAGHAPAREQEPPPNPAPAAPAPGEDDPSSWASPRRRKGGLRRTRPTGPREEATA 123
Query: 147 QRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPIGV---ESREPADAAIREKRAKIKEMM 203
R + + + + + F P +G ES+EP + +R +R KIKEMM
Sbjct: 124 ARGNSIPASRPGDEGVPFRFDFNAFRSRLRHPVLGTRADESQEP-QSQVRAQREKIKEMM 182
Query: 204 KHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAKSW 263
+ AW +YK YA G NEL+P++K G+ ++FG + GAT++D+LDTL++ME+K EF+EAK+W
Sbjct: 183 QFAWQSYKRYAMGKNELRPLTKDGYEGNMFGGLSGATVIDSLDTLYLMELKEEFQEAKAW 242
Query: 264 VEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPAFHTPSGIP 323
V E+ NV+ E S+FEVNIR++GGLLSA+YL+GEE+FR KA+ LG KLLPAF+TP+GIP
Sbjct: 243 VGESFHLNVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRIKAIRLGEKLLPAFNTPTGIP 302
Query: 324 WALLNMKSGIGRNWPWASGGSS-ILAEFGTLHLEFMHLSHLSGNPIFAEKVMNIRTVLNK 382
+++ KSG NW WA+ GSS ILAEFG+LHLEF+HL+ LSGN +FAEKV NIR VL K
Sbjct: 303 KGVVSFKSG---NWGWATAGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRK 359
Query: 383 LEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKTDLEAKKMYFDAVQ 442
+EKP GLYPN+L+P SG W QHHVSVGGLGDSFYEYL+K+WLMS KTD+EAK MY++A++
Sbjct: 360 IEKPFGLYPNFLSPVSGNWVQHHVSVGGLGDSFYEYLIKSWLMSGKTDMEAKNMYYEALE 419
Query: 443 AIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGA 502
AIET+L+ S GLTYIAEW+GG+L+HKMGHL CF+GGM ALGA+ A E HY EL A
Sbjct: 420 AIETYLLNVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIALGAEDAKEEKRAHYRELAA 479
Query: 503 EIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDP 562
+I +TCHESY R+ KLGPEAF F+ G EA+AT+ +E YYILRPEV+E+YMY+WR TH+P
Sbjct: 480 QITKTCHESYARSDTKLGPEAFWFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNP 539
Query: 563 KYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDD 622
YR+W WE V ALE +CR G+SG++DVY ++D+ QQSFFLAETLKYLYL+FS+DD
Sbjct: 540 IYREWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDD 599
Query: 623 LLPLEHWIFNSEAHLLPILPKD 644
LL LE W+FN+EAH LP+ D
Sbjct: 600 LLSLEDWVFNTEAHPLPVNHSD 621
>gi|218749883 alpha 1,2-mannosidase [Homo sapiens]
Length = 699
Score = 327 bits (838), Expect = 2e-89
Identities = 211/635 (33%), Positives = 338/635 (53%), Gaps = 50/635 (7%)
Query: 37 RLTEKFVLLLVFSAFITLCFGAIFF-------------LPDSSKL---LSGVLFHSSPAL 80
RL +L L+ AF+ C G +F+ L + K+ ++G+ + P L
Sbjct: 80 RLQRNMILFLL--AFLLFC-GLLFYINLADHWKALAFRLEEEQKMRPEIAGLKPANPPVL 136
Query: 81 QPAADHKPGPGARAEDAAEGRARRREEGAPG----DPEAALEDNLARIRENHERALREAK 136
P E +++ R + G P P L+D E A + +
Sbjct: 137 PAPQKADTDPENLPEISSQKTQRHIQRGPPHLQIRPPSQDLKDG------TQEEATKRQE 190
Query: 137 ETLQKLPE-EIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPIGVESREPADAAIREK 195
+ PE + QR ++ + V + + + P R V PP+ + + +
Sbjct: 191 APVDPRPEGDPQRTVISWRGAVIEPEQGTELPSRRAE-VPTKPPLPPARTQGTPVHLNYR 249
Query: 196 RAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKH 255
+ + ++ HAW Y+ +AWG +ELKP+S+ S FG G T++DALDT++I+ ++
Sbjct: 250 QKGVIDVFLHAWKGYRKFAWGHDELKPVSRS--FSEWFG--LGLTLIDALDTMWILGLRK 305
Query: 256 EFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPA 315
EFEEA+ WV + L F + ++++FE IR +GGLLSAY+LSG+ +F +KA + G +L+PA
Sbjct: 306 EFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSLFLRKAEDFGNRLMPA 365
Query: 316 FHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGNPIFAEKVMN 375
F TPS IP++ +N+ +G+ W S S +AE ++ LEF LS L+G+ F E V
Sbjct: 366 FRTPSKIPYSDVNIGTGVAHPPRWTS--DSTVAEVTSIQLEFRELSRLTGDKKFQEAVEK 423
Query: 376 IRTVLNKLE-KPQGLYPNYLNPSSGQWGQHHV-SVGGLGDSFYEYLLKAWLMSDKTDLEA 433
+ ++ L K GL P ++N SG + V ++G DS+YEYLLK W+ K + +
Sbjct: 424 VTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYYEYLLKQWIQGGKQETQL 483
Query: 434 KKMYFDAVQAIETHLIRKSS-SGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEG 492
+ Y +A++ + THL+R S S LT++ E G KM HL CF G ALG G
Sbjct: 484 LEDYVEAIEGVRTHLLRHSEPSKLTFVGELAHGRFSAKMDHLVCFLPGTLALG---VYHG 540
Query: 493 MAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFD----GGVEAIATRQNEKYYILRPEV 548
+ ++EL E+ TC++ + L PE F+ G + + +++ +LRPE
Sbjct: 541 LPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYPQPGRRDVEVKPADRHNLLRPET 600
Query: 549 METYMYMWRLTHDPKYRKWAWEAVEALENHCRV-NGGYSGLRDVYLLHESYD-DVQQSFF 606
+E+ Y++R+T D KY+ W WE +++ RV +GGYS + +V + D +SFF
Sbjct: 601 VESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGYSSINNVQDPQKPEPRDKMESFF 660
Query: 607 LAETLKYLYLIFSDD-DLLPLEHWIFNSEAHLLPI 640
L ETLKYL+L+FSDD +LL L+ ++FN+EAH LPI
Sbjct: 661 LGETLKYLFLLFSDDPNLLSLDAYVFNTEAHPLPI 695
>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
[Homo sapiens]
Length = 932
Score = 191 bits (484), Expect = 2e-48
Identities = 158/495 (31%), Positives = 240/495 (48%), Gaps = 79/495 (15%)
Query: 188 ADAAIREKRAK----IKEMMKHAWNNYKGYAWGLNELKPISKGGH---SSSLFGNIKGA- 239
A+ RE++ K + EM HA+ NY +A+ +EL P++ G G++ A
Sbjct: 41 AEPMSREEKQKLGNQVLEMFDHAYGNYMEHAYPADELMPLTCRGRVRGQEPSRGDVDDAL 100
Query: 240 -----TIVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYY 294
T++D+LDTL ++ EFE+A V +++ + + +SVFE NIR +GGLL +
Sbjct: 101 GKFSLTLIDSLDTLVVLNKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHS 160
Query: 295 LS------GE------EIFRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASG 342
L+ GE + + A +LG KLLPAF+T SG+P+ +N+K GI + P A
Sbjct: 161 LAIMLKEKGEYMQWYNDELLQMAKQLGYKLLPAFNTTSGLPYPRINLKFGIRK--PEART 218
Query: 343 GS---SILAEFGTLHLEFMHLSHLSGNPIFAEKVMNIRTVL-NKLEKPQGLYPNYLNPSS 398
G+ + A GTL LEF LS +G IF E L K ++ L +N +
Sbjct: 219 GTETDTCTACAGTLILEFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHT 278
Query: 399 GQWGQHHVSVGGLGDSFYEYLLKAW-LMSDKTDLEAKKMYFDAVQ--------AIETHLI 449
G W + VG DS+YEYLLKA+ L+ D + LE ++DA+ ++ H+
Sbjct: 279 GDWVRKDSGVGAGIDSYYEYLLKAYVLLGDDSFLERFNTHYDAIMRYISQPPLLLDVHIH 338
Query: 450 RKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIARTCH 509
+ + T+ M L F G+ L D P A H
Sbjct: 339 KPMLNARTW------------MDALLAFFPGLQVLKGDIRP--------------AIETH 372
Query: 510 ESYNRTFMKLG--PEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKW 567
E + K PEAF D R + + LRPE E+ ++++ T DP Y +
Sbjct: 373 EMLYQVIKKHNFLPEAFTTD-------FRVHWAQHPLRPEFAESTYFLYKATGDPYYLEV 425
Query: 568 AWEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSD--DDLLP 625
+E L + RV G++ ++DV S++D SFFLAE KYLYL+F+D D +
Sbjct: 426 GKTLIENLNKYARVPCGFAAMKDVRT--GSHEDRMDSFFLAEMFKYLYLLFADKEDIIFD 483
Query: 626 LEHWIFNSEAHLLPI 640
+E +IF +EAHLLP+
Sbjct: 484 IEDYIFTTEAHLLPL 498
>gi|222537737 ER degradation enhancer, mannosidase alpha-like 2
isoform 1 [Homo sapiens]
Length = 578
Score = 186 bits (473), Expect = 4e-47
Identities = 154/518 (29%), Positives = 251/518 (48%), Gaps = 79/518 (15%)
Query: 167 PFRGLPPVDFVPPI--------GVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLN 218
PFR L P+ + + G + P A RE+ +K M HA+++Y A+ +
Sbjct: 2 PFRLLIPLGLLCALLPQHHGAPGPDGSAPDPAHYRER---VKAMFYHAYDSYLENAFPFD 58
Query: 219 ELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISV 278
EL+P++ GH + +G+ T++DALDTL I+ EF+ +++++DF+++ SV
Sbjct: 59 ELRPLTCDGHDT--WGSFS-LTLIDALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASV 115
Query: 279 FEVNIRFVGGLLSAYYLS---GEEI---------FRKKAVELGVKLLPAFHTPSGIPWAL 326
FE NIR VGGLLSA+ LS G E+ + A E KLLPAF TP+G+P+
Sbjct: 116 FETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGT 175
Query: 327 LNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGNPIFAEKVMNIRTVLNKLEKP 386
+N+ G+ + A GT +EF LS L+G+P+F + L +
Sbjct: 176 VNLLHGVNP----GETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSD 231
Query: 387 QGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLK-AWLMSDKTDLEAKKMYFDAVQAIE 445
GL N+++ +G+W +G DS++EYL+K A L+ DK + M+ + +AI
Sbjct: 232 IGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDK---KLMAMFLEYNKAIR 288
Query: 446 THLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIA 505
+ + ++ +KG + L + G+ +L D + A
Sbjct: 289 NY--TRFDDWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGD--------------IDNA 332
Query: 506 RTCHESYNRTFMKLG--PEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPK 563
+Y + + G PE + G T + + Y LRPE++E+ MY++R T DP
Sbjct: 333 MRTFLNYYTVWKQFGGLPEFYNIPQGY----TVEKREGYPLRPELIESAMYLYRATGDPT 388
Query: 564 YRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDD- 622
+ +AVE++E +V G++ ++D L D+ +SFFLAET+KYLYL+F +
Sbjct: 389 LLELGRDAVESIEKISKVECGFATIKD--LRDHKLDNRMESFFLAETVKYLYLLFDPTNF 446
Query: 623 ------------------LLPLEHWIFNSEAHLLPILP 642
+L +IFN+EAH PI P
Sbjct: 447 IHNNGSTFDAVITPYGECILGAGGYIFNTEAH--PIDP 482
>gi|222537739 ER degradation enhancer, mannosidase alpha-like 2
isoform 2 [Homo sapiens]
Length = 541
Score = 166 bits (419), Expect = 8e-41
Identities = 132/437 (30%), Positives = 212/437 (48%), Gaps = 65/437 (14%)
Query: 240 TIVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLS--- 296
T++DALDTL I+ EF+ +++++DF+++ SVFE NIR VGGLLSA+ LS
Sbjct: 40 TLIDALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLLSKKA 99
Query: 297 GEEI---------FRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSIL 347
G E+ + A E KLLPAF TP+G+P+ +N+ G+ +
Sbjct: 100 GVEVEAGWPCSGPLLRMAEEAARKLLPAFQTPTGMPYGTVNLLHGVNP----GETPVTCT 155
Query: 348 AEFGTLHLEFMHLSHLSGNPIFAEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVS 407
A GT +EF LS L+G+P+F + L + GL N+++ +G+W
Sbjct: 156 AGIGTFIVEFATLSSLTGDPVFEDVARVALMRLWESRSDIGLVGNHIDVLTGKWVAQDAG 215
Query: 408 VGGLGDSFYEYLLK-AWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGL 466
+G DS++EYL+K A L+ DK + M+ + +AI + + ++ +KG +
Sbjct: 216 IGAGVDSYFEYLVKGAILLQDK---KLMAMFLEYNKAIRNY--TRFDDWYLWVQMYKGTV 270
Query: 467 LEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLG--PEAF 524
L + G+ +L D + A +Y + + G PE +
Sbjct: 271 SMPVFQSLEAYWPGLQSLIGD--------------IDNAMRTFLNYYTVWKQFGGLPEFY 316
Query: 525 RFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGG 584
G T + + Y LRPE++E+ MY++R T DP + +AVE++E +V G
Sbjct: 317 NIPQGY----TVEKREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECG 372
Query: 585 YSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDD-------------------LLP 625
++ ++D L D+ +SFFLAET+KYLYL+F + +L
Sbjct: 373 FATIKD--LRDHKLDNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILG 430
Query: 626 LEHWIFNSEAHLLPILP 642
+IFN+EAH PI P
Sbjct: 431 AGGYIFNTEAH--PIDP 445
>gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Homo
sapiens]
Length = 657
Score = 164 bits (415), Expect = 2e-40
Identities = 138/485 (28%), Positives = 235/485 (48%), Gaps = 65/485 (13%)
Query: 194 EKRAKIKEMMKHAWNNYKGYAWGLNELKPI-------SKGGHSSSLFGNIKG---ATIVD 243
+ R + M ++NY +A+ +EL PI +G S+ ++ G T+VD
Sbjct: 129 QMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVD 188
Query: 244 ALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYL--SGEEIF 301
ALDTL IM EF++A V + F+ ++ + VFE IR +G LLSA+ + ++ F
Sbjct: 189 ALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPF 248
Query: 302 RKKAV------------ELGVKLLPAF-HTPSGIPWALLNMKSGIGRNWPWASGGSSILA 348
+ +L V+LLPAF +T +GIP+ +N+K+G+ P + + A
Sbjct: 249 GDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGV----PPDTNNETCTA 304
Query: 349 EFGTLHLEFMHLSHLSGNPIFAEKVMN-IRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVS 407
G+L +EF LS L G+ F ++ + N GL N +N +G W
Sbjct: 305 GAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSG 364
Query: 408 VGGLGDSFYEYLLKAW-LMSDKTDLEAKKMYFDAVQAIETHLIRKSSSG---------LT 457
+G DSFYEYLLK++ L +K DLE M+ A Q+I+ +L R +
Sbjct: 365 LGAGLDSFYEYLLKSYILFGEKEDLE---MFNAAYQSIQNYLRRGREACNEGEGDPPLYV 421
Query: 458 YIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFM 517
+ + G L+ + L F G+ L D E A H Y +
Sbjct: 422 NVNMFSGQLMNTWIDSLQAFFPGLQVLIGD--------------VEDAICLHAFYYAIWK 467
Query: 518 KLGPEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALEN 577
+ G R++ ++A + +Y LRPE++E+ +++ T +P Y + +++LE
Sbjct: 468 RYGALPERYNWQLQA----PDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEK 523
Query: 578 HCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDDLLPLE--HWIFNSEA 635
+ +V GY+ L +++ +S +D +SFFL+ET KYLYL+F +D+ + ++F +E
Sbjct: 524 YTKVKCGYATLH--HVIDKSTEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEG 581
Query: 636 HLLPI 640
H++ +
Sbjct: 582 HIVSV 586
>gi|139394621 chondroitin sulfate proteoglycan 5 (neuroglycan C)
precursor [Homo sapiens]
Length = 539
Score = 35.8 bits (81), Expect = 0.13
Identities = 33/106 (31%), Positives = 44/106 (41%), Gaps = 16/106 (15%)
Query: 20 GGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSSPA 79
G GGGG +G P LLL A + L GA+ S + + L SPA
Sbjct: 2 GRAGGGGPGRGPPP----------LLLFLGAALVLASGAVPAREAGSAVEAEELVKGSPA 51
Query: 80 LQPAAD---HKPGPGARAEDAAEGRARRREEGAPGDPEAALEDNLA 122
+P A+ + GP A ED A A G PE L+++ A
Sbjct: 52 WEPPANDTREEAGPPAAGEDEASWTA---PGGELAGPEEVLQESAA 94
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 34.7 bits (78), Expect = 0.28
Identities = 20/75 (26%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 119 DNLARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDK----APFRGLP-- 172
D L + RE + +++ +K ++++R+ L ++ V + R+ AP G+P
Sbjct: 1087 DALIKRREYLDEQIKKVSNKTEKTEDDVEREAQLVEQWVGLTEERNAVLVPAPGSGIPGA 1146
Query: 173 PVDFVPPIGVESREP 187
P D++PP G+E+ P
Sbjct: 1147 PADWIPPPGMETHIP 1161
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 34.7 bits (78), Expect = 0.28
Identities = 20/75 (26%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 119 DNLARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDK----APFRGLP-- 172
D L + RE + +++ +K ++++R+ L ++ V + R+ AP G+P
Sbjct: 1087 DALIKRREYLDEQIKKVSNKTEKTEDDVEREAQLVEQWVGLTEERNAVLVPAPGSGIPGA 1146
Query: 173 PVDFVPPIGVESREP 187
P D++PP G+E+ P
Sbjct: 1147 PADWIPPPGMETHIP 1161
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 34.7 bits (78), Expect = 0.28
Identities = 20/75 (26%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 119 DNLARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDK----APFRGLP-- 172
D L + RE + +++ +K ++++R+ L ++ V + R+ AP G+P
Sbjct: 1100 DALIKRREYLDEQIKKVSNKTEKTEDDVEREAQLVEQWVGLTEERNAVLVPAPGSGIPGA 1159
Query: 173 PVDFVPPIGVESREP 187
P D++PP G+E+ P
Sbjct: 1160 PADWIPPPGMETHIP 1174
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 34.7 bits (78), Expect = 0.28
Identities = 20/75 (26%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 119 DNLARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDK----APFRGLP-- 172
D L + RE + +++ +K ++++R+ L ++ V + R+ AP G+P
Sbjct: 1100 DALIKRREYLDEQIKKVSNKTEKTEDDVEREAQLVEQWVGLTEERNAVLVPAPGSGIPGA 1159
Query: 173 PVDFVPPIGVESREP 187
P D++PP G+E+ P
Sbjct: 1160 PADWIPPPGMETHIP 1174
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 34.3 bits (77), Expect = 0.37
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 10/74 (13%)
Query: 63 PDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALE--DN 120
P++++ + +PA P D +P PG R EDAA + APG P A E +
Sbjct: 893 PEAAERPPAPVLDMAPAGHPEGDAEPSPGERVEDAAAPK-------APG-PSPAKEKIGS 944
Query: 121 LARIRENHERALRE 134
L ++ H R+ RE
Sbjct: 945 LRKVDRGHYRSRRE 958
>gi|119220564 one cut domain, family member 2 [Homo sapiens]
Length = 504
Score = 34.3 bits (77), Expect = 0.37
Identities = 15/21 (71%), Positives = 15/21 (71%)
Query: 13 PAGGVLGGGLGGGGGRKGSGP 33
PAGG GGG GGGGG G GP
Sbjct: 35 PAGGGSGGGGGGGGGGGGGGP 55
>gi|4502565 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 33.9 bits (76), Expect = 0.48
Identities = 18/36 (50%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 3 VGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRL 38
+GGL+ S GG GGG GGGGG G G A+R+
Sbjct: 29 LGGLI---SGAGGGGGGGGGGGGGGGGGGGGTAMRI 61
>gi|51599151 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 33.9 bits (76), Expect = 0.48
Identities = 18/36 (50%), Positives = 22/36 (61%), Gaps = 3/36 (8%)
Query: 3 VGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRL 38
+GGL+ S GG GGG GGGGG G G A+R+
Sbjct: 29 LGGLI---SGAGGGGGGGGGGGGGGGGGGGGTAMRI 61
>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
Length = 1001
Score = 33.9 bits (76), Expect = 0.48
Identities = 32/113 (28%), Positives = 48/113 (42%), Gaps = 3/113 (2%)
Query: 93 RAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRDILL 152
RA +AA R + G+ A L + E + A RE + + EE +R L
Sbjct: 825 RAREAASLRQHEKTRGSLVAQAQAWGQELKALLEKYNTACREVGRLREAVAEERRRSGDL 884
Query: 153 EKKKVAQDQLRDKAPFRGLPP-VDFVPPIGVESREPADAAIREKRAKIKEMMK 204
+ A +Q R + RG + + E E A R+K AKIKE++K
Sbjct: 885 AAQ--AAEQERQASEMRGRSEQFEKTAELLKEKMEHLIGACRDKEAKIKELLK 935
>gi|223633890 hypothetical protein LOC729956 [Homo sapiens]
Length = 538
Score = 33.5 bits (75), Expect = 0.63
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 4/85 (4%)
Query: 14 AGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVL 73
AG + GG GG GGR G GP + +V+ V S + + GA +S+
Sbjct: 162 AGWLEGGRTGGAGGRGGEGPGG---STAYVVCGVISFALAVGVGAKVAFSKASRAPRAHR 218
Query: 74 FHSSP-ALQPAADHKPGPGARAEDA 97
+ P AL H+ GPG R + A
Sbjct: 219 DINVPRALVDILRHQAGPGTRPDRA 243
>gi|169205008 PREDICTED: hypothetical protein [Homo sapiens]
Length = 234
Score = 32.7 bits (73), Expect = 1.1
Identities = 49/174 (28%), Positives = 66/174 (37%), Gaps = 30/174 (17%)
Query: 6 LLPLFSSPAGGV---------LGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCF 56
L PLF S + V + GGLGG G R G+G A + +A +
Sbjct: 65 LEPLFLSMSEAVAAALGELSGINGGLGGDGSRSGAGAAGTQAHGVQGRRGSAAAAVLGLH 124
Query: 57 GAIF--FLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPE 114
G IF FLP KL + AAD PG + GR G PG E
Sbjct: 125 GDIFPCFLPWLLKL-----------GREAADGAVKPGGSGDRGRGGRGSGVRAG-PGGAE 172
Query: 115 AALEDNLARIRENHERAL----REAKETLQKLPEEIQRDILLEKKKVAQDQLRD 164
AA E RE A+ +T + D+L E ++VA+ L++
Sbjct: 173 AAGE---GEAREGRGLAVSVSGTSVSDTATDTRPWAEADLLREWRRVAKQHLKE 223
>gi|169205607 PREDICTED: hypothetical protein [Homo sapiens]
Length = 234
Score = 32.7 bits (73), Expect = 1.1
Identities = 49/174 (28%), Positives = 66/174 (37%), Gaps = 30/174 (17%)
Query: 6 LLPLFSSPAGGV---------LGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCF 56
L PLF S + V + GGLGG G R G+G A + +A +
Sbjct: 65 LEPLFLSMSEAVAAALGELSGINGGLGGDGSRSGAGAAGTQAHGVQGRRGSAAAAVLGLH 124
Query: 57 GAIF--FLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPE 114
G IF FLP KL + AAD PG + GR G PG E
Sbjct: 125 GDIFPCFLPWLLKL-----------GREAADGAVKPGGSGDRGRGGRGSGVRAG-PGGAE 172
Query: 115 AALEDNLARIRENHERAL----REAKETLQKLPEEIQRDILLEKKKVAQDQLRD 164
AA E RE A+ +T + D+L E ++VA+ L++
Sbjct: 173 AAGE---GEAREGRGLAVSVSGTSVSDTATDTRPWAEADLLREWRRVAKQHLKE 223
>gi|169204476 PREDICTED: hypothetical protein [Homo sapiens]
Length = 234
Score = 32.7 bits (73), Expect = 1.1
Identities = 49/174 (28%), Positives = 66/174 (37%), Gaps = 30/174 (17%)
Query: 6 LLPLFSSPAGGV---------LGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCF 56
L PLF S + V + GGLGG G R G+G A + +A +
Sbjct: 65 LEPLFLSMSEAVAAALGELSGINGGLGGDGSRSGAGAAGTQAHGVQGRRGSAAAAVLGLH 124
Query: 57 GAIF--FLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPE 114
G IF FLP KL + AAD PG + GR G PG E
Sbjct: 125 GDIFPCFLPWLLKL-----------GREAADGAVKPGGSGDRGRGGRGSGVRAG-PGGAE 172
Query: 115 AALEDNLARIRENHERAL----REAKETLQKLPEEIQRDILLEKKKVAQDQLRD 164
AA E RE A+ +T + D+L E ++VA+ L++
Sbjct: 173 AAGE---GEAREGRGLAVSVSGTSVSDTATDTRPWAEADLLREWRRVAKQHLKE 223
>gi|55749424 transcription elongation factor A (SII)-like 1 [Homo
sapiens]
Length = 159
Score = 32.7 bits (73), Expect = 1.1
Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 4/115 (3%)
Query: 90 PGARAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRD 149
P E+ + + EE P E + E + + E++ E + LPE + +
Sbjct: 4 PRKENEEEPQSAPKTDEERPP--VEHSPEKQSPEEQSSEEQSSEEEFFPEELLPELLP-E 60
Query: 150 ILLEKKKVAQDQLRDKAPFRGLPPVDFVPPIGVESREPADAAIREKRAKIKEMMK 204
+LL +++ Q+ L K F G PP++ PP GV + + + +E+ A+ + +
Sbjct: 61 MLLSEERPPQEGLSRKDLFEGRPPME-QPPCGVGKHKLEEGSFKERLARSRPQFR 114
>gi|55749406 transcription elongation factor A (SII)-like 1 [Homo
sapiens]
Length = 159
Score = 32.7 bits (73), Expect = 1.1
Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 4/115 (3%)
Query: 90 PGARAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRD 149
P E+ + + EE P E + E + + E++ E + LPE + +
Sbjct: 4 PRKENEEEPQSAPKTDEERPP--VEHSPEKQSPEEQSSEEQSSEEEFFPEELLPELLP-E 60
Query: 150 ILLEKKKVAQDQLRDKAPFRGLPPVDFVPPIGVESREPADAAIREKRAKIKEMMK 204
+LL +++ Q+ L K F G PP++ PP GV + + + +E+ A+ + +
Sbjct: 61 MLLSEERPPQEGLSRKDLFEGRPPME-QPPCGVGKHKLEEGSFKERLARSRPQFR 114
>gi|55749397 transcription elongation factor A (SII)-like 1 [Homo
sapiens]
Length = 159
Score = 32.7 bits (73), Expect = 1.1
Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 4/115 (3%)
Query: 90 PGARAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRD 149
P E+ + + EE P E + E + + E++ E + LPE + +
Sbjct: 4 PRKENEEEPQSAPKTDEERPP--VEHSPEKQSPEEQSSEEQSSEEEFFPEELLPELLP-E 60
Query: 150 ILLEKKKVAQDQLRDKAPFRGLPPVDFVPPIGVESREPADAAIREKRAKIKEMMK 204
+LL +++ Q+ L K F G PP++ PP GV + + + +E+ A+ + +
Sbjct: 61 MLLSEERPPQEGLSRKDLFEGRPPME-QPPCGVGKHKLEEGSFKERLARSRPQFR 114
>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
sapiens]
Length = 425
Score = 32.7 bits (73), Expect = 1.1
Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 17/97 (17%)
Query: 4 GGLLPLFSSPAGGVLGGGLGGG--GGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIFF 61
GG + F AGG GGG GGG G + G A+ LT + +AF G +
Sbjct: 330 GGAVGAFGGAAGGAGGGGGGGGGAGAERDRGGASGFLT-------LHNAFPKEAGGGV-- 380
Query: 62 LPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAA 98
+ ++G + PA P A P PG A++AA
Sbjct: 381 ----TVTVTGP--PAPPAPAPPAPSAPAPGTLAKEAA 411
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 32.3 bits (72), Expect = 1.4
Identities = 15/29 (51%), Positives = 17/29 (58%)
Query: 83 AADHKPGPGARAEDAAEGRARRREEGAPG 111
A D +PGP A A + RAR RE G PG
Sbjct: 380 AFDERPGPIQIASQARDARAREREAGRPG 408
Score = 30.4 bits (67), Expect = 5.4
Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 10/49 (20%)
Query: 89 GPGARAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKE 137
G G ED + RAR REE G AR+ + E+ LRE+KE
Sbjct: 718 GHGRADEDCVDDRARHREERLLG----------ARLDRDQEKLLRESKE 756
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 32.0 bits (71), Expect = 1.8
Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 14/122 (11%)
Query: 95 EDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRDILLEK 154
E+ A+ + +E DP+ L+D L R + + ++ +E +K ++ +++ + K
Sbjct: 582 EEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKV--K 639
Query: 155 KKVAQDQLRDKAPFRGLPPVDFVPPI---GVESREPA---------DAAIREKRAKIKEM 202
K +D+++ AP LPP + P+ SR PA + E++ K+KE
Sbjct: 640 DKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEK 699
Query: 203 MK 204
K
Sbjct: 700 EK 701
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 32.0 bits (71), Expect = 1.8
Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 93 RAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRDILL 152
R E + RR +E + E E R ER L+E ++ L+ E++QR++
Sbjct: 702 RREQERREQERREQERQLAEQERRREQE----RLQAERELQEREKALRLQKEQLQRELEE 757
Query: 153 EKKKVAQDQLRDK 165
+KKK Q +L ++
Sbjct: 758 KKKKEEQQRLAER 770
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 32.0 bits (71), Expect = 1.8
Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 93 RAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRDILL 152
R E + RR +E + E E R ER L+E ++ L+ E++QR++
Sbjct: 698 RREQERREQERREQERQLAEQERRREQE----RLQAERELQEREKALRLQKEQLQRELEE 753
Query: 153 EKKKVAQDQLRDK 165
+KKK Q +L ++
Sbjct: 754 KKKKEEQQRLAER 766
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,422,186
Number of Sequences: 37866
Number of extensions: 1259269
Number of successful extensions: 8000
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 7409
Number of HSP's gapped (non-prelim): 490
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.