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Search of human proteins with 24308141
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
(304 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 597 e-171
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 333 1e-91
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 96 4e-20
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 96 4e-20
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 89 5e-18
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 89 6e-18
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 86 3e-17
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 85 7e-17
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 84 2e-16
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 77 1e-14
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 75 7e-14
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 73 3e-13
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 73 3e-13
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 72 8e-13
gi|27262638 sperm associated antigen 1 [Homo sapiens] 70 2e-12
gi|27262636 sperm associated antigen 1 [Homo sapiens] 70 2e-12
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 67 1e-11
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 67 2e-11
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 67 2e-11
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 66 4e-11
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 65 7e-11
gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens] 65 1e-10
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 64 1e-10
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 63 3e-10
gi|19923193 heat shock 70kD protein binding protein [Homo sapiens] 60 3e-09
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 57 2e-08
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 57 2e-08
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 57 2e-08
gi|4503729 FK506 binding protein 52 [Homo sapiens] 57 2e-08
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens] 56 3e-08
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 597 bits (1539), Expect = e-171
Identities = 304/304 (100%), Positives = 304/304 (100%)
Query: 1 MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDTHLAVSQPLTE 60
MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDTHLAVSQPLTE
Sbjct: 1 MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDTHLAVSQPLTE 60
Query: 61 MFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAV 120
MFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAV
Sbjct: 61 MFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAV 120
Query: 121 YYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKAL 180
YYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKAL
Sbjct: 121 YYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKAL 180
Query: 181 DLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQNPQVQQL 240
DLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQNPQVQQL
Sbjct: 181 DLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQNPQVQQL 240
Query: 241 MSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSA 300
MSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSA
Sbjct: 241 MSGMMTNAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHIRSRSFSSSA 300
Query: 301 EEHS 304
EEHS
Sbjct: 301 EEHS 304
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 333 bits (854), Expect = 1e-91
Identities = 182/311 (58%), Positives = 230/311 (73%), Gaps = 10/311 (3%)
Query: 1 MSSIKHLVYAVIRFLREQSQMDTYTSDEQESLEVAIQCLETVFKISPEDTHLAVSQPLTE 60
M + K L YA+I+FL +Q + +SD QESLEVAIQCLET F ++ ED+ LA+ Q L E
Sbjct: 1 MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPE 60
Query: 61 MF----TSSFCKNDVLPLSNSVP--EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIEL 114
+F T D+ + + P ED +A++LK EGN MK EN+ AAV Y +AIEL
Sbjct: 61 IFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIEL 120
Query: 115 DPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVT 174
+P NAVY+CNRAAA SKLG+Y A++DCE+AI ID YSKAYGRMGLAL++LNK EAV
Sbjct: 121 NPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVA 180
Query: 175 SYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNPAFISMAASLMQN 234
Y+KAL+LDP+N++YKSNLKIAE KLRE SPTG SFD+A L+NNP F+SMA++LM N
Sbjct: 181 YYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNN 240
Query: 235 PQVQQLMSGMMT---NAIGGPAAGVGGLTDLSSLIQAGQQFAQQIQQQNPELIEQLRNHI 291
PQ+QQLMSGM++ N +G P DL+SLIQAGQQFAQQ+QQQNPELIEQLR+ I
Sbjct: 241 PQIQQLMSGMISGGNNPLGTPGTS-PSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQI 299
Query: 292 RSRSFSSSAEE 302
RSR+ S+S ++
Sbjct: 300 RSRTPSASNDD 310
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 95.9 bits (237), Expect = 4e-20
Identities = 49/120 (40%), Positives = 70/120 (58%)
Query: 81 DVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIK 140
D KA LK++GN + K+ Y A+DCYT+ ++ DP N V NRA+A +L + A
Sbjct: 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAES 188
Query: 141 DCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL 200
DC A+A++ Y+KAY R G A AL K EEA Y++ L+L+P N + L+ Q L
Sbjct: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248
Score = 89.7 bits (221), Expect = 3e-18
Identities = 49/116 (42%), Positives = 66/116 (56%), Gaps = 1/116 (0%)
Query: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAI 148
KD GN KE Y A++CYT+ I D NA+ NRA A K+ Y +A KDC +AI +
Sbjct: 286 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 345
Query: 149 DSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNL-KIAEQKLREV 203
D YSKA+ R G A T L K EA ++ L L+P N + L KI ++ L++V
Sbjct: 346 DGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKV 401
Score = 32.3 bits (72), Expect = 0.53
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 15/117 (12%)
Query: 89 KDEGNNHMKEENYAAAVDCYTQAI--ELDPNNAVYYCNRAAAQSKLGHYTDAIK-DCEKA 145
++ N +K +Y A I ELD +++ + ++S+ D I D +KA
Sbjct: 78 EENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESE----EDGIHVDSQKA 133
Query: 146 IAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
+ + K +K Y + G K++EA+ Y K +D DP N +N A +L++
Sbjct: 134 LVLKEKGNK-YFKQG-------KYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 95.9 bits (237), Expect = 4e-20
Identities = 49/120 (40%), Positives = 70/120 (58%)
Query: 81 DVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIK 140
D KA LK++GN + K+ Y A+DCYT+ ++ DP N V NRA+A +L + A
Sbjct: 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAES 188
Query: 141 DCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL 200
DC A+A++ Y+KAY R G A AL K EEA Y++ L+L+P N + L+ Q L
Sbjct: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248
Score = 88.6 bits (218), Expect = 6e-18
Identities = 47/114 (41%), Positives = 63/114 (55%)
Query: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAI 148
KD GN KE Y A++CYT+ I D NA+ NRA A K+ Y +A KDC +AI +
Sbjct: 286 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 345
Query: 149 DSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
D YSKA+ R G A T L K EA ++ L L+P N + L +++L E
Sbjct: 346 DGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 399
Score = 32.3 bits (72), Expect = 0.53
Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 15/117 (12%)
Query: 89 KDEGNNHMKEENYAAAVDCYTQAI--ELDPNNAVYYCNRAAAQSKLGHYTDAIK-DCEKA 145
++ N +K +Y A I ELD +++ + ++S+ D I D +KA
Sbjct: 78 EENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESE----EDGIHVDSQKA 133
Query: 146 IAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
+ + K +K Y + G K++EA+ Y K +D DP N +N A +L++
Sbjct: 134 LVLKEKGNK-YFKQG-------KYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 89.0 bits (219), Expect = 5e-18
Identities = 52/160 (32%), Positives = 86/160 (53%), Gaps = 8/160 (5%)
Query: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCE 143
+ ++LK++GN + N A+ CY++AI+LDP+N V Y NR+AA +K G Y A +D
Sbjct: 3 QVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGC 62
Query: 144 KAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL--R 201
K + + + K Y R AL LN+FEEA +Y++ L + N K L+ E +L R
Sbjct: 63 KTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAER 122
Query: 202 EVSSPTGTGLSFDMASLINNPAFISMAASLMQNPQVQQLM 241
+ +P F+M +L +L+ +P ++L+
Sbjct: 123 KFMNP------FNMPNLYQKLESDPRTRTLLSDPTYRELI 156
Score = 78.6 bits (192), Expect = 6e-15
Identities = 51/154 (33%), Positives = 80/154 (51%), Gaps = 17/154 (11%)
Query: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAI 148
K++GN ++ +Y A+ YT+AI+ +P +A Y NRAA +KL + A+KDCE+ I +
Sbjct: 364 KNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQL 423
Query: 149 DSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTG 208
+ + K Y R AL A+ + +A+ YQKALDLD S+ K A +
Sbjct: 424 EPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLD-------SSCKEAADGYQRCM---- 472
Query: 209 TGLSFDMASLINNPAFISMAASLMQNPQVQQLMS 242
MA + + + M +P+VQQ+MS
Sbjct: 473 ------MAQYNRHDSPEDVKRRAMADPEVQQIMS 500
Score = 65.5 bits (158), Expect = 6e-11
Identities = 37/115 (32%), Positives = 63/115 (54%), Gaps = 7/115 (6%)
Query: 73 PLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKL 132
P+ +PE+ +A + K+ GN+ K++++ A+ Y +A ELDP N Y N+AA +
Sbjct: 213 PMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEK 272
Query: 133 GHYTDAIKDCEKAIAID-------SKYSKAYGRMGLALTALNKFEEAVTSYQKAL 180
G Y + CEKAI + + +KAY R+G + K+++A+ Y K+L
Sbjct: 273 GDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSL 327
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 88.6 bits (218), Expect = 6e-18
Identities = 47/114 (41%), Positives = 63/114 (55%)
Query: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAI 148
KD GN KE Y A++CYT+ I D NA+ NRA A K+ Y +A KDC +AI +
Sbjct: 127 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 186
Query: 149 DSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
D YSKA+ R G A T L K EA ++ L L+P N + L +++L E
Sbjct: 187 DGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
Score = 67.0 bits (162), Expect = 2e-11
Identities = 35/89 (39%), Positives = 50/89 (56%)
Query: 112 IELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEE 171
++ DP N V NRA+A +L + A DC A+A++ Y+KAY R G A AL K EE
Sbjct: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60
Query: 172 AVTSYQKALDLDPENDSYKSNLKIAEQKL 200
A Y++ L+L+P N + L+ Q L
Sbjct: 61 AKKDYERVLELEPNNFEATNELRKISQAL 89
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 86.3 bits (212), Expect = 3e-17
Identities = 47/118 (39%), Positives = 65/118 (55%), Gaps = 5/118 (4%)
Query: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNN----AVYYCNRAAAQSKLGHYTDAIKDCEK 144
K++GN KE NY A + YT+A+ +DPNN A YCNR SKL DAI+DC
Sbjct: 260 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTN 319
Query: 145 AIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
A+ +D Y KAY R ++EEAV Y+K + + +K LK A+ +LR+
Sbjct: 320 AVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE-KTKEHKQLLKNAQLELRK 376
Score = 75.1 bits (183), Expect = 7e-14
Identities = 37/113 (32%), Positives = 66/113 (58%)
Query: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCE 143
+A+ K++GN + +++Y A + YT+AI++ P NA YY NRAA LG + +A+ D +
Sbjct: 27 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ 86
Query: 144 KAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIA 196
+++ +D + + + R G +L A S+Q+AL+LD +N + K A
Sbjct: 87 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNA 139
Score = 33.1 bits (74), Expect = 0.31
Identities = 22/91 (24%), Positives = 43/91 (47%)
Query: 97 KEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAY 156
++ ++ V C +A+E P + +A + LG Y +A + +DS + A
Sbjct: 154 EKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADAL 213
Query: 157 GRMGLALTALNKFEEAVTSYQKALDLDPEND 187
GL L + E+AV + +AL + P+++
Sbjct: 214 YVRGLCLYYEDCIEKAVQFFVQALRMAPDHE 244
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 85.1 bits (209), Expect = 7e-17
Identities = 46/118 (38%), Positives = 65/118 (55%), Gaps = 5/118 (4%)
Query: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNN----AVYYCNRAAAQSKLGHYTDAIKDCEK 144
K++GN KE NY A + YT+A+ +DPNN A YCNR SKL DAI+DC
Sbjct: 204 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTN 263
Query: 145 AIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202
A+ +D Y KAY R ++EEAV Y+K + + +K LK A+ +L++
Sbjct: 264 AVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE-KTKEHKQLLKNAQLELKK 320
Score = 53.5 bits (127), Expect = 2e-07
Identities = 27/81 (33%), Positives = 44/81 (54%)
Query: 116 PNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTS 175
P NA YY NRAA LG + +A+ D ++++ +D + + + R G +L A S
Sbjct: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62
Query: 176 YQKALDLDPENDSYKSNLKIA 196
+Q+AL+LD +N + K A
Sbjct: 63 FQRALELDHKNAQAQQEFKNA 83
Score = 33.1 bits (74), Expect = 0.31
Identities = 22/91 (24%), Positives = 43/91 (47%)
Query: 97 KEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAY 156
++ ++ V C +A+E P + +A + LG Y +A + +DS + A
Sbjct: 98 EKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADAL 157
Query: 157 GRMGLALTALNKFEEAVTSYQKALDLDPEND 187
GL L + E+AV + +AL + P+++
Sbjct: 158 YVRGLCLYYEDCIEKAVQFFVQALRMAPDHE 188
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 84.0 bits (206), Expect = 2e-16
Identities = 45/123 (36%), Positives = 71/123 (57%), Gaps = 4/123 (3%)
Query: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCE 143
+A++LK + N++ K ++Y A+ Y+QAIEL+P+NA+YY NR+ A + Y A+ D
Sbjct: 27 RAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDAT 86
Query: 144 KAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEND----SYKSNLKIAEQK 199
+AI +D KY K Y R + AL KF A+ Y+ + + P + Y+ KI +QK
Sbjct: 87 RAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQK 146
Query: 200 LRE 202
E
Sbjct: 147 AFE 149
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 77.4 bits (189), Expect = 1e-14
Identities = 49/151 (32%), Positives = 76/151 (50%), Gaps = 2/151 (1%)
Query: 37 QCLETVFK--ISPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVPEDVGKADQLKDEGNN 94
+C T+ K ISP T + ++ + + + D + E+ AD LK++GN
Sbjct: 56 ECRTTLNKTMISPPQTAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADALKEKGNE 115
Query: 95 HMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSK 154
E NY A+ Y++ +E + V Y NRA A KL Y A+ DCE A+ D K +K
Sbjct: 116 AFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTK 175
Query: 155 AYGRMGLALTALNKFEEAVTSYQKALDLDPE 185
AY MG A AL + + Y+K L+++P+
Sbjct: 176 AYFHMGKANLALKNYSVSRECYKKILEINPK 206
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 75.1 bits (183), Expect = 7e-14
Identities = 42/126 (33%), Positives = 65/126 (51%), Gaps = 5/126 (3%)
Query: 79 PEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDA 138
PE A +LK++GN Y A CY +AI +P AVYY NRA K+ + A
Sbjct: 20 PEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQA 79
Query: 139 IKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPE-----NDSYKSNL 193
+ DC +A+ +D + KA+ +G + ++EA+ + Q+A L E D S L
Sbjct: 80 LADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSAL 139
Query: 194 KIAEQK 199
+IA++K
Sbjct: 140 RIAKKK 145
>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
Length = 929
Score = 73.2 bits (178), Expect = 3e-13
Identities = 43/122 (35%), Positives = 66/122 (54%), Gaps = 3/122 (2%)
Query: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAV---YYCNRAAAQSKLGHYTDAIK 140
+A QLK+EGN H + ++Y AA + Y+QA++L + A+ Y NRAA K Y A
Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64
Query: 141 DCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL 200
D +AI I+S KA R AL L K ++A Q+ L+P N +++ L+ +
Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Query: 201 RE 202
+E
Sbjct: 125 QE 126
>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
Length = 931
Score = 73.2 bits (178), Expect = 3e-13
Identities = 43/122 (35%), Positives = 66/122 (54%), Gaps = 3/122 (2%)
Query: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAV---YYCNRAAAQSKLGHYTDAIK 140
+A QLK+EGN H + ++Y AA + Y+QA++L + A+ Y NRAA K Y A
Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64
Query: 141 DCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL 200
D +AI I+S KA R AL L K ++A Q+ L+P N +++ L+ +
Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Query: 201 RE 202
+E
Sbjct: 125 QE 126
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 71.6 bits (174), Expect = 8e-13
Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 2/113 (1%)
Query: 76 NSVPE--DVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLG 133
N VP DV KA LK+EGN +K+ N+ A++ Y++++ + Y NRA L
Sbjct: 182 NRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLK 241
Query: 134 HYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEN 186
YT+A+KDC +A+ +D K KA+ R A AL ++ + L ++P N
Sbjct: 242 QYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRN 294
Score = 52.8 bits (125), Expect = 4e-07
Identities = 36/113 (31%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 79 PEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIEL-------DPNN-AVYYCNRAAAQS 130
P+ ++L+ GN + YA A Y +A+ + DP +V Y NRAA
Sbjct: 3 PKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHL 62
Query: 131 KLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLD 183
K G+ D IKDC A+A+ K R A AL K+ A Y+ L +D
Sbjct: 63 KDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 70.5 bits (171), Expect = 2e-12
Identities = 45/127 (35%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 85 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEK 144
A + K++GN +Y AV YT++I P V Y NRA A+ KL ++ A +DCEK
Sbjct: 209 ATREKEKGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEK 267
Query: 145 AIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLR--E 202
+ ++ KA R NK EA K LD++P+ND K L E+ L+ E
Sbjct: 268 VLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSE 327
Query: 203 VSSPTGT 209
+S T T
Sbjct: 328 AASETQT 334
Score = 61.6 bits (148), Expect = 8e-10
Identities = 31/107 (28%), Positives = 57/107 (53%)
Query: 88 LKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIA 147
LK+EGN + ++NY A+ Y++ ++++ Y NRA KL + +A +DC++A+
Sbjct: 626 LKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQ 685
Query: 148 IDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLK 194
+ KA+ R LA L +++++ K + LDP K L+
Sbjct: 686 LADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEAKMELE 732
Score = 48.1 bits (113), Expect = 9e-06
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 8/104 (7%)
Query: 88 LKDEGNNHMKEENYAAAVDCYTQAI--------ELDPNNAVYYCNRAAAQSKLGHYTDAI 139
LK +GN + +A A Y+ AI E+ + ++ Y NRAA K G+ + I
Sbjct: 448 LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCI 507
Query: 140 KDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLD 183
+DC +A+ + K R +A L ++ +A Y+ L +D
Sbjct: 508 QDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQID 551
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 70.5 bits (171), Expect = 2e-12
Identities = 45/127 (35%), Positives = 64/127 (50%), Gaps = 3/127 (2%)
Query: 85 ADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEK 144
A + K++GN +Y AV YT++I P V Y NRA A+ KL ++ A +DCEK
Sbjct: 209 ATREKEKGNEAFNSGDYEEAVMYYTRSISALPT-VVAYNNRAQAEIKLQNWNSAFQDCEK 267
Query: 145 AIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLR--E 202
+ ++ KA R NK EA K LD++P+ND K L E+ L+ E
Sbjct: 268 VLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSE 327
Query: 203 VSSPTGT 209
+S T T
Sbjct: 328 AASETQT 334
Score = 61.6 bits (148), Expect = 8e-10
Identities = 31/107 (28%), Positives = 57/107 (53%)
Query: 88 LKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIA 147
LK+EGN + ++NY A+ Y++ ++++ Y NRA KL + +A +DC++A+
Sbjct: 626 LKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQ 685
Query: 148 IDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLK 194
+ KA+ R LA L +++++ K + LDP K L+
Sbjct: 686 LADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEAKMELE 732
Score = 48.1 bits (113), Expect = 9e-06
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 8/104 (7%)
Query: 88 LKDEGNNHMKEENYAAAVDCYTQAI--------ELDPNNAVYYCNRAAAQSKLGHYTDAI 139
LK +GN + +A A Y+ AI E+ + ++ Y NRAA K G+ + I
Sbjct: 448 LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCI 507
Query: 140 KDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLD 183
+DC +A+ + K R +A L ++ +A Y+ L +D
Sbjct: 508 QDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQID 551
>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
sapiens]
Length = 420
Score = 67.4 bits (163), Expect = 1e-11
Identities = 45/136 (33%), Positives = 66/136 (48%), Gaps = 12/136 (8%)
Query: 80 EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAI 139
E+ + LKD+GN ENY AA++ Y AI L+ + Y NRAA KL + AI
Sbjct: 285 EEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAI 344
Query: 140 KDCEKAIAI--------DSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKS 191
+D KA+ + + KA+ R G A L + E + Y+ AL +DP N
Sbjct: 345 EDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSN----K 400
Query: 192 NLKIAEQKLREVSSPT 207
++I +K+R V T
Sbjct: 401 IVQIDAEKIRNVIQGT 416
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 67.0 bits (162), Expect = 2e-11
Identities = 45/127 (35%), Positives = 67/127 (52%), Gaps = 7/127 (5%)
Query: 86 DQLKDEGNNHMKEENYAAAVDCYTQAIELDP---NNAVYYCNRAAAQSKLGHYTDAIKDC 142
+QL+ EGN K +Y A+ YTQA+ LD + AV + NRAA KL Y A +
Sbjct: 7 EQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEA 66
Query: 143 EKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLK----IAEQ 198
KAI D KA R AL L + ++AV Q+ + L+P+N ++ L+ ++
Sbjct: 67 SKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQE 126
Query: 199 KLREVSS 205
K+R +SS
Sbjct: 127 KVRYMSS 133
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 67.0 bits (162), Expect = 2e-11
Identities = 45/127 (35%), Positives = 67/127 (52%), Gaps = 7/127 (5%)
Query: 86 DQLKDEGNNHMKEENYAAAVDCYTQAIELDP---NNAVYYCNRAAAQSKLGHYTDAIKDC 142
+QL+ EGN K +Y A+ YTQA+ LD + AV + NRAA KL Y A +
Sbjct: 22 EQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEA 81
Query: 143 EKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLK----IAEQ 198
KAI D KA R AL L + ++AV Q+ + L+P+N ++ L+ ++
Sbjct: 82 SKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQE 141
Query: 199 KLREVSS 205
K+R +SS
Sbjct: 142 KVRYMSS 148
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 65.9 bits (159), Expect = 4e-11
Identities = 31/96 (32%), Positives = 54/96 (56%)
Query: 91 EGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDS 150
+ N + ++ A+ Y +A+ +DP N + Y NR+AA K+ Y A+ D KA ++
Sbjct: 64 QSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNP 123
Query: 151 KYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEN 186
K+ KAY R G+AL L + +A+ ++ L DP++
Sbjct: 124 KWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKS 159
Score = 38.1 bits (87), Expect = 0.010
Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 12/123 (9%)
Query: 72 LPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPN------NAVYYCNR 125
L ++ + + +A L + GN H Y A Y Q + L P+ N
Sbjct: 581 LNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNL 640
Query: 126 AAAQSKLGHYTDAIKDCEKAIAIDS------KYSKAYGRMGLALTALNKFEEAVTSYQKA 179
A LG+Y +A+K E+ +A+ +KAY +GLA AL F +A +
Sbjct: 641 GYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYL 700
Query: 180 LDL 182
L L
Sbjct: 701 LSL 703
Score = 36.6 bits (83), Expect = 0.028
Identities = 27/128 (21%), Positives = 54/128 (42%), Gaps = 12/128 (9%)
Query: 67 CKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPN------NAV 120
C L +++ + E KA + G+ H + NY A+ C + + + + +
Sbjct: 939 CFEKRLVVAHELGEAFNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESD 998
Query: 121 YYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYS------KAYGRMGLALTALNKFEEAVT 174
C ++G Y A++ + + I + + +AYG +GL +L FE AV
Sbjct: 999 AACGLGGVYQQMGEYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESLGTFERAVV 1058
Query: 175 SYQKALDL 182
++ L +
Sbjct: 1059 YQEQHLSI 1066
Score = 34.7 bits (78), Expect = 0.11
Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 15/103 (14%)
Query: 95 HMKEENYAAAVDCYTQAIEL-----DPN-NAVYYCNRAAAQSKLGHYTDAIKDCEKAIAI 148
+M Y A CY + ++L DP+ A Y N + + +AI E+ +A+
Sbjct: 804 YMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAM 863
Query: 149 DSKYS---------KAYGRMGLALTALNKFEEAVTSYQKALDL 182
+ S +AYG +G AL +EEA+ Y++ L +
Sbjct: 864 LQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSV 906
Score = 32.0 bits (71), Expect = 0.70
Identities = 26/104 (25%), Positives = 42/104 (40%), Gaps = 23/104 (22%)
Query: 169 FEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVSSPTGTGLSFDMASLINNP------ 222
F A+ Y +AL +DP+N SN A K+++ + A L+N
Sbjct: 74 FHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIK---ARLLNPKWPKAYF 130
Query: 223 --------------AFISMAASLMQNPQVQQLMSGMMTNAIGGP 252
A + A+ L Q+P+ QL+ GM+ A+ P
Sbjct: 131 RQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSP 174
Score = 32.0 bits (71), Expect = 0.70
Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 12/80 (15%)
Query: 133 GHYTDAIKDCEKAIAIDSKYS------KAYGRMGLALTALNKFEEAVTSYQKALDLDPE- 185
G Y A+K + + I + S +AYG MG A AL +++AV +++ L + E
Sbjct: 488 GDYDTALKLHKTHLCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEV 547
Query: 186 ND-----SYKSNLKIAEQKL 200
ND S NL +A Q L
Sbjct: 548 NDRASQASTHGNLAVAYQAL 567
Score = 31.2 bits (69), Expect = 1.2
Identities = 26/116 (22%), Positives = 47/116 (40%), Gaps = 18/116 (15%)
Query: 67 CKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRA 126
CK D+ + +G A Q+KD ++ YAA Y + D
Sbjct: 726 CKKDINGAIKFYEQQLGLAHQVKDR---RLEASAYAALGTAYRMIQKYD----------- 771
Query: 127 AAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDL 182
LG++T ++ ++ + + +A+G + AL K+ A Y++ LDL
Sbjct: 772 ---KALGYHTQELEVYQELSDLPGE-CRAHGHLAAVYMALGKYTMAFKCYEEQLDL 823
Score = 28.5 bits (62), Expect = 7.7
Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 20/127 (15%)
Query: 72 LPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQS- 130
L ++ ++ + G+ + G+ + NY A+ + + L A+ +R AA S
Sbjct: 261 LDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQLVL----AMKLKDREAASSA 316
Query: 131 --KLGHYTDAIKDCEKAIA------IDSKYSK-------AYGRMGLALTALNKFEEAVTS 175
LGH AI D A+A + +K SK G MG A+ FE AV
Sbjct: 317 LSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQC 376
Query: 176 YQKALDL 182
+++ L +
Sbjct: 377 HEQHLKI 383
>gi|73747840 LON peptidase N-terminal domain and ring finger 3
isoform 1 [Homo sapiens]
Length = 759
Score = 65.1 bits (157), Expect = 7e-11
Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 5/134 (3%)
Query: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCE 143
+A QL+ EGN +E AA+ Y +A++L PN+ + Y NR+ L + +A+ D E
Sbjct: 242 RASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAE 301
Query: 144 KAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEN-----DSYKSNLKIAEQ 198
A + KA+ R AL L K EEA+ + + LD +N ++ + NL++
Sbjct: 302 IACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPHC 361
Query: 199 KLREVSSPTGTGLS 212
+E ++ G G S
Sbjct: 362 SSQEEAAARGDGSS 375
>gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens]
Length = 387
Score = 64.7 bits (156), Expect = 1e-10
Identities = 44/121 (36%), Positives = 62/121 (51%), Gaps = 6/121 (4%)
Query: 67 CKNDVLPLSNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIE---LDPN-NAVYY 122
C ++ PE+ K KDEGN++ KE++Y AV YT+ ++ DP+ NAV Y
Sbjct: 63 CLQSIIFDEERSPEEQAKT--YKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLY 120
Query: 123 CNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDL 182
NRAAAQ LG++ A+ D A + + KA R L L F EAV + L +
Sbjct: 121 TNRAAAQYYLGNFRSALNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQI 180
Query: 183 D 183
D
Sbjct: 181 D 181
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 64.3 bits (155), Expect = 1e-10
Identities = 35/106 (33%), Positives = 58/106 (54%), Gaps = 5/106 (4%)
Query: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPN-----NAVYYCNRAAAQSKLGHYTDA 138
++ +LK+EGN K+ +Y A Y++A+E+ P+ ++ + NRAAA+ K A
Sbjct: 115 ESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMA 174
Query: 139 IKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDP 184
I DC KAI ++ Y +A R +K +EA+ Y+ L+ DP
Sbjct: 175 INDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDP 220
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 63.2 bits (152), Expect = 3e-10
Identities = 44/163 (26%), Positives = 75/163 (46%), Gaps = 7/163 (4%)
Query: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNN-----AVYYCNRAAAQSKLGHYTDA 138
+A K++GN + K Y A+ CYT+AI L P + +Y NRAAA +L + +
Sbjct: 113 RAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEV 172
Query: 139 IKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQ 198
+DC KA+ ++ KY KA R A L+ +E + L E + ++ +A++
Sbjct: 173 AQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCIL--EGFQNQQSMLLADK 230
Query: 199 KLREVSSPTGTGLSFDMASLINNPAFISMAASLMQNPQVQQLM 241
L+ + + L+ +P FI S + + Q M
Sbjct: 231 VLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPM 273
Score = 44.7 bits (104), Expect = 1e-04
Identities = 38/161 (23%), Positives = 73/161 (45%), Gaps = 9/161 (5%)
Query: 30 ESLEVAIQCLETVFKISPEDTHLAVSQPLTEMFTSSFCKNDVLPLSNSVP--EDVGKADQ 87
+ +E A+ + ++ PE LA +Q ++ ++ N+ + ++ E+V K
Sbjct: 415 DQVEEAVADFDECIRLRPESA-LAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFP 473
Query: 88 LKDEG-----NNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTD-AIKD 141
EG ++ + A + Y + I+L+P+NA Y ++ Q + D ++
Sbjct: 474 RCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLEL 533
Query: 142 CEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDL 182
KAI ID+K AY MG E+A+ + KA++L
Sbjct: 534 ISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINL 574
Score = 35.0 bits (79), Expect = 0.082
Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query: 81 DVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAA---QSKLGHYTD 137
D AD G + + AV + + I L P +A+ + A Q+ G+ +
Sbjct: 397 DPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSS 456
Query: 138 ----AIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEN 186
A+K E+ I + ++ Y ALT +F +A Y K +DL+P+N
Sbjct: 457 QIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDN 509
>gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]
Length = 369
Score = 59.7 bits (143), Expect = 3e-09
Identities = 42/165 (25%), Positives = 77/165 (46%), Gaps = 13/165 (7%)
Query: 52 LAVSQPLTEMFTSSFCKNDVLPLSNSVPEDVGK-----ADQLKDEGNNH-------MKEE 99
L +P +E K V+ P+++G +++ D+ N+ + +
Sbjct: 69 LKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAEITEEMMDQANDKKVAAIEALNDG 128
Query: 100 NYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRM 159
A+D +T AI+L+P A+ Y RA+ KL AI+DC++AI I+ ++ Y
Sbjct: 129 ELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINPDSAQPYKWR 188
Query: 160 GLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLREVS 204
G A L +EEA A LD + D+ + LK + + ++++
Sbjct: 189 GKAHRLLGHWEEAAHDLALACKLDYDEDA-SAMLKEVQPRAQKIA 232
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 57.0 bits (136), Expect = 2e-08
Identities = 26/81 (32%), Positives = 47/81 (58%)
Query: 122 YCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALD 181
+ N A KL YT A++ C+KA+ +DS K R G A +N+FE A ++K L+
Sbjct: 320 FLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLE 379
Query: 182 LDPENDSYKSNLKIAEQKLRE 202
++P+N + + + + ++K +E
Sbjct: 380 VNPQNKAARLQISMCQKKAKE 400
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 57.0 bits (136), Expect = 2e-08
Identities = 26/81 (32%), Positives = 47/81 (58%)
Query: 122 YCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALD 181
+ N A KL YT A++ C+KA+ +DS K R G A +N+FE A ++K L+
Sbjct: 320 FLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLE 379
Query: 182 LDPENDSYKSNLKIAEQKLRE 202
++P+N + + + + ++K +E
Sbjct: 380 VNPQNKAARLQISMCQKKAKE 400
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 57.0 bits (136), Expect = 2e-08
Identities = 26/81 (32%), Positives = 47/81 (58%)
Query: 122 YCNRAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALD 181
+ N A KL YT A++ C+KA+ +DS K R G A +N+FE A ++K L+
Sbjct: 320 FLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLE 379
Query: 182 LDPENDSYKSNLKIAEQKLRE 202
++P+N + + + + ++K +E
Sbjct: 380 VNPQNKAARLQISMCQKKAKE 400
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 57.0 bits (136), Expect = 2e-08
Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 15/137 (10%)
Query: 80 EDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVY---------------YCN 124
E + ++ +K+ G + KE Y A+ Y + + + + + N
Sbjct: 265 EKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLN 324
Query: 125 RAAAQSKLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDP 184
A KL ++ AI+ C KA+ +DS K R G A A+N FE A +QK L L P
Sbjct: 325 LAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYP 384
Query: 185 ENDSYKSNLKIAEQKLR 201
N + K+ L + +Q++R
Sbjct: 385 NNKAAKTQLAVCQQRIR 401
>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 56.2 bits (134), Expect = 3e-08
Identities = 36/129 (27%), Positives = 69/129 (53%), Gaps = 5/129 (3%)
Query: 75 SNSVPEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGH 134
+ S + + + + +K +GN +E + A+ YT+AIE P N + Y NRA + G
Sbjct: 221 TQSCMDCIEEGELMKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQ 280
Query: 135 YTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDL---DPE--NDSY 189
+ +A+ D ++A + + + K + R AL+ L +++ A+ + KA L DPE D
Sbjct: 281 FRNALGDGKRATILKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLI 340
Query: 190 KSNLKIAEQ 198
+ ++K+ +Q
Sbjct: 341 QQHVKLQKQ 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,122,398
Number of Sequences: 37866
Number of extensions: 407470
Number of successful extensions: 1649
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 1294
Number of HSP's gapped (non-prelim): 307
length of query: 304
length of database: 18,247,518
effective HSP length: 102
effective length of query: 202
effective length of database: 14,385,186
effective search space: 2905807572
effective search space used: 2905807572
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.