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Search of human proteins with 239752495
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]
(237 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239752495 PREDICTED: similar to nebulin [Homo sapiens] 493 e-140
gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] 357 7e-99
gi|115527120 nebulin [Homo sapiens] 253 8e-68
gi|46049092 nebulin-related anchoring protein isoform C [Homo sa... 159 3e-39
gi|46049105 nebulin-related anchoring protein isoform S [Homo sa... 159 3e-39
gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 62 3e-10
gi|47087157 nebulette non-muscle isoform [Homo sapiens] 37 0.011
gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 37 0.019
gi|127138957 zinc finger protein 537 [Homo sapiens] 30 1.4
gi|222352158 carboxypeptidase 3, cytosolic [Homo sapiens] 30 2.4
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 30 2.4
gi|110349721 titin isoform novex-3 [Homo sapiens] 29 4.1
gi|110349719 titin isoform N2-A [Homo sapiens] 29 4.1
gi|110349717 titin isoform novex-2 [Homo sapiens] 29 4.1
gi|110349713 titin isoform novex-1 [Homo sapiens] 29 4.1
gi|110349715 titin isoform N2-B [Homo sapiens] 29 4.1
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 28 5.3
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 28 5.3
gi|45446749 kinesin family member 5A [Homo sapiens] 28 5.3
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 28 5.3
gi|19923424 myotubularin related protein 9 [Homo sapiens] 28 9.0
gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens] 28 9.0
>gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]
Length = 237
Score = 493 bits (1269), Expect = e-140
Identities = 237/237 (100%), Positives = 237/237 (100%)
Query: 1 MHLSCLFPKPHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60
MHLSCLFPKPHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD
Sbjct: 1 MHLSCLFPKPHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60
Query: 61 REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120
REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA
Sbjct: 61 REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120
Query: 121 YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP 180
YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP
Sbjct: 121 YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP 180
Query: 181 EVIQAKINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQWELSELSAMWTYPSDN 237
EVIQAKINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQWELSELSAMWTYPSDN
Sbjct: 181 EVIQAKINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQWELSELSAMWTYPSDN 237
>gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]
Length = 410
Score = 357 bits (915), Expect = 7e-99
Identities = 177/188 (94%), Positives = 178/188 (94%), Gaps = 6/188 (3%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS
Sbjct: 50 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 109
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL
Sbjct: 110 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 169
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV------E 196
PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE E
Sbjct: 170 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWE 229
Query: 197 KSRDNFNV 204
K + N NV
Sbjct: 230 KEKANVNV 237
Score = 136 bits (342), Expect = 2e-32
Identities = 62/104 (59%), Positives = 78/104 (75%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
Y YK Y KQ GH++G R+ ++DPK VWA + K+Q+DR YKKAY K + P+DM+S
Sbjct: 293 YLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVS 352
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSD 126
I AK+ Q L SD+DYR+YLH W+C PDQNDVIQA+KAYDLQSD
Sbjct: 353 ISAAKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
Score = 45.4 bits (106), Expect = 4e-05
Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 15/194 (7%)
Query: 39 FRTLQDDPKSVWA-IHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDID 97
F ++ D P+ + A I+A +I S+ Y+ A+EK K N P D ++Q+K + +S+
Sbjct: 200 FTSIVDTPEVIQAKINAVQI-SEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKR 258
Query: 98 YRN-----YLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGW-LPEGSVEV 149
Y+ + + D + AK + D+ SD LYK+ E KG IG + ++
Sbjct: 259 YQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKEDPKL 318
Query: 150 MRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHY 207
+ N + N+RLY+ K + VD + AK S+V+ + H+
Sbjct: 319 VWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDY---RHYLHHW 375
Query: 208 GSYLDQKQLGPAQQ 221
+ DQ + A++
Sbjct: 376 SCFPDQNDVIQARK 389
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 253 bits (647), Expect = 8e-68
Identities = 121/198 (61%), Positives = 151/198 (76%), Gaps = 12/198 (6%)
Query: 9 KPHTYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAK 56
K YDL L +P YKYKEGYRKQLGHH+G R ++DDPK +W+IH AK
Sbjct: 3495 KKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAK 3554
Query: 57 IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQ 116
IQSDREYKK +EK K ++P+DM+ +V AKKCQ+LVSDIDY++ LH+WTCLPDQNDVIQ
Sbjct: 3555 IQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQ 3614
Query: 117 AKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI 176
A+KAYDLQSD +YKSDLEWL+GIGW+P GSVEV +VK A +L++R YR + LKFT I
Sbjct: 3615 ARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCI 3674
Query: 177 VDTPEVIQAKINAVQISE 194
DTPE++ AK NA+ +S+
Sbjct: 3675 TDTPEIVLAKNNALTMSK 3692
Score = 249 bits (635), Expect = 2e-66
Identities = 115/171 (67%), Positives = 143/171 (83%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
YKYKE Y KQ GHH+G ++++DDPK + AIHA KIQS+REYKK ++K K ++P+DM+S
Sbjct: 3764 YKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLS 3823
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
I+ AKKCQ LV+DIDYRNYLH+WTC+PDQND+IQAKKAYDLQSD LYK+DLEWL+GIGW+
Sbjct: 3824 ILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWM 3883
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQIS 193
P+GS EV+RVKNAQN+ + +YR LK+TSIVDTPEV+ AK NA IS
Sbjct: 3884 PQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENIS 3934
Score = 248 bits (632), Expect = 4e-66
Identities = 116/198 (58%), Positives = 148/198 (74%), Gaps = 12/198 (6%)
Query: 9 KPHTYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAK 56
K YDL +P YKYKE YRKQLGHH+G R + DDPK +W++H AK
Sbjct: 3252 KKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAK 3311
Query: 57 IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQ 116
+QSDREYKK +EK K +++P+DM+ IV AKKCQ LVSD+DY++ LH+W CLPDQND+I
Sbjct: 3312 VQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIH 3371
Query: 117 AKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI 176
A+KAYDLQSDNLYKSDLEW+KGIGW+P S+EV+R K A LL++ +YR +PE LKFTSI
Sbjct: 3372 ARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSI 3431
Query: 177 VDTPEVIQAKINAVQISE 194
DTPE + AK NA+ +++
Sbjct: 3432 TDTPEQVLAKNNALNMNK 3449
Score = 245 bits (626), Expect = 2e-65
Identities = 106/175 (60%), Positives = 145/175 (82%)
Query: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79
+ YKYK+GYRKQLGHH+G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+D
Sbjct: 3032 ISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVD 3091
Query: 80 MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139
M+ +V AKKCQ LVSD+DY+NYLH+WTCLPDQNDVI A++AYDLQSDN+YKSDL+WL+GI
Sbjct: 3092 MLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGI 3151
Query: 140 GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
GW+P GS++V++ K A +L++ +YR P+ LKFTS+ D+ E + AK NA+ +++
Sbjct: 3152 GWVPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNK 3206
Score = 237 bits (605), Expect = 6e-63
Identities = 103/172 (59%), Positives = 142/172 (82%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
+KYKEGYRKQLGHH+G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+DM+
Sbjct: 2792 FKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 2851
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
+V AKKCQ LVSD+DY+NYLHQWTCLPDQ+DVI A++AYDLQSDN+YKSDL+W++GIGW+
Sbjct: 2852 VVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWV 2911
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
GS++V + K A +L++++YR P+ KFTS+ D+ E + AK NA+ +++
Sbjct: 2912 SIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNK 2963
Score = 236 bits (603), Expect = 1e-62
Identities = 108/193 (55%), Positives = 146/193 (75%), Gaps = 12/193 (6%)
Query: 13 YDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60
YDL + +P YKYKEG+RKQLGHH+G R ++DDPK +W++H AKIQSD
Sbjct: 2527 YDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSD 2586
Query: 61 REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120
REYKK +EK K ++P+DM+ +V AKKCQ LVSD+DY+NYLHQWTCLPDQ+DVI A++A
Sbjct: 2587 REYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQA 2646
Query: 121 YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP 180
YDLQSDNLYKSDL+WLKGIGW+ GS+E + K A +L++ +YR P+ KF+S++D+
Sbjct: 2647 YDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSI 2706
Query: 181 EVIQAKINAVQIS 193
++ AK NA+ ++
Sbjct: 2707 PMVLAKNNAITMN 2719
Score = 236 bits (602), Expect = 1e-62
Identities = 108/172 (62%), Positives = 139/172 (80%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
YKYK+GYRKQLGHH+GFR+LQDDPK V +++ AK+QS+REYKK +EK K ++P+DM+
Sbjct: 2306 YKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLG 2365
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
+V AKKCQ LVSD+DY+NYLHQWTCLPDQNDV+QAKK Y+LQS+NLYKSDLEWL+GIGW
Sbjct: 2366 VVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWS 2425
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
P GS+E + K A +++E+ YR P+ KFTSI D +++ AK NA S+
Sbjct: 2426 PLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSD 2477
Score = 204 bits (518), Expect = 7e-53
Identities = 102/184 (55%), Positives = 136/184 (73%), Gaps = 7/184 (3%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYK + KQ GH++G T++DDPK VW HA +IQ++R YK+ Y K+K N P DM+S+
Sbjct: 4249 KYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSV 4308
Query: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
+ AK+ Q LVSDIDYRNYLHQW C PDQNDVIQA+KAYDLQSDN+Y++DLEWL+GIGW+P
Sbjct: 4309 LAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIP 4368
Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQISEVEKSR 199
SV+ +RV Q ++++ Y K AL+ F S+VD PE++ AKIN+V S+V K +
Sbjct: 4369 LDSVDHVRVTKNQEMMSQIKY--KKNALENYPNFRSVVDPPEIVLAKINSVNQSDV-KYK 4425
Query: 200 DNFN 203
+ FN
Sbjct: 4426 ETFN 4429
Score = 198 bits (504), Expect = 3e-51
Identities = 92/178 (51%), Positives = 128/178 (71%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
YKYK + KQ GH++G T +DD K WA+ A K+Q++REY+ + K K +P+DM+S
Sbjct: 4006 YKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLS 4065
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
I+ +K Q LVSD+DYRNYLHQWTC+PDQNDVIQAKKAY+LQSDN+YK+DLEWL+GIGW+
Sbjct: 4066 ILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWM 4125
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
P SV V K+A ++ +E+ YR K E L FT + D + + AK + + +++ +D
Sbjct: 4126 PNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKD 4183
Score = 189 bits (481), Expect = 1e-48
Identities = 93/184 (50%), Positives = 131/184 (71%), Gaps = 1/184 (0%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
+YK+ Y K G +GF++LQDDPK V ++ AKIQSDREYKK YEK+K +NTP DM ++
Sbjct: 1087 QYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNV 1146
Query: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWL 142
V AKK Q +VS+++Y++ LH +T LPD D+ +K +QSDN+YK D W+KGIGW+
Sbjct: 1147 VAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWI 1206
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNF 202
P GS++V +VK A + LNE+ YR P+ LKFTSIVD+P ++QAK N Q+S++
Sbjct: 1207 PIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGE 1266
Query: 203 NVRH 206
+V+H
Sbjct: 1267 DVKH 1270
Score = 176 bits (446), Expect = 2e-44
Identities = 86/172 (50%), Positives = 118/172 (68%), Gaps = 1/172 (0%)
Query: 25 YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIV 84
YK+ Y K G +G ++ DDPK + ++ AK QSDREY+K YEKSK I+ PLDM+ +
Sbjct: 844 YKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVT 903
Query: 85 QAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLP 143
QAKK Q + SD+DY++ LH ++ PD +V AKKAY LQSD YK+D W+KG GW+P
Sbjct: 904 QAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVP 963
Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195
GS+E+ + K A ++LNE+ YR P+ LKFTSI D P +Q+KIN Q S++
Sbjct: 964 FGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDI 1015
Score = 172 bits (437), Expect = 2e-43
Identities = 85/185 (45%), Positives = 124/185 (67%), Gaps = 1/185 (0%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
YKYKE Y K G H+GFR+LQDDPK V ++ AK+QSDREYKK YE +K ++TP DM+S
Sbjct: 1330 YKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVS 1389
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGW 141
I AK Q + ++++Y+ LH +T LPD + + +QSDN+YK + +LKGIGW
Sbjct: 1390 ITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGW 1449
Query: 142 LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201
+P GS+EV +VK A + LNER YR P+ +KFTS+ D+ ++ A+ N Q+S++ +
Sbjct: 1450 IPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEG 1509
Query: 202 FNVRH 206
++H
Sbjct: 1510 EKLKH 1514
Score = 167 bits (424), Expect = 6e-42
Identities = 86/172 (50%), Positives = 114/172 (66%), Gaps = 1/172 (0%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYKE Y K G +GF +LQDDPK V ++ AKIQSDREYKK YE SK ++TPLDM+S+
Sbjct: 1575 KYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSV 1634
Query: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWL 142
AKK Q + ++ +YR H +T LPD +V ++ A +QSDNLYKSD W+KGIGW+
Sbjct: 1635 TAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWV 1694
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
P S+EV + K A +L+E+ YR PE LKFT +DT E K N + + +
Sbjct: 1695 PIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDK 1746
Score = 166 bits (421), Expect = 1e-41
Identities = 80/173 (46%), Positives = 120/173 (69%), Gaps = 1/173 (0%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
YKYK+ Y + G H+GFR+L+DDPK V + AK+QSDREYKK YEKSK +TP+DM+S
Sbjct: 1818 YKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLS 1877
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSD-LEWLKGIGW 141
+V AKK Q + ++ +YRN +H + LPD AK +QSDN YK+D +++KGIGW
Sbjct: 1878 VVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGW 1937
Query: 142 LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194
LP GS+E + K A +++E+ YR P+ LK+++++D+ ++ A+ NA ++E
Sbjct: 1938 LPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNE 1990
Score = 148 bits (374), Expect = 4e-36
Identities = 71/168 (42%), Positives = 107/168 (63%), Gaps = 1/168 (0%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
YKYK Y K G +GFR+L+DDPK V ++ AK+QSDREYKK YE +K ++TP DM+S
Sbjct: 2062 YKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLS 2121
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGW 141
+ AK Q +++ +Y++ +H++ LPD ++ + +QSDN YK D EW KG+GW
Sbjct: 2122 VTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGW 2181
Query: 142 LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINA 189
P GS+EV + K A +++ YR P +F + D+ +++ AK NA
Sbjct: 2182 SPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNA 2229
Score = 129 bits (325), Expect = 2e-30
Identities = 66/182 (36%), Positives = 109/182 (59%), Gaps = 3/182 (1%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYKE Y KQ GH++ + + + P V + K++S Y+K YE +K + P DMM+
Sbjct: 4494 KYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNH 4553
Query: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
V AK+CQ ++SD++YR+Y HQWT L ++ +VI+ + A ++ SDN+YK DL WLKGIG
Sbjct: 4554 VLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYV 4613
Query: 144 EGSVEVMRVKNAQNLLNERLYRI--KPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201
+ +++ K + +L ++ Y K + + DTP + A + + SEV K ++N
Sbjct: 4614 WDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEV-KYKEN 4672
Query: 202 FN 203
++
Sbjct: 4673 YH 4674
Score = 107 bits (268), Expect = 7e-24
Identities = 67/176 (38%), Positives = 95/176 (53%), Gaps = 8/176 (4%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMS 82
KY+E Y K + R++ DDP + + K+ DR Y+ YEK+K IH P DM+
Sbjct: 4739 KYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVP-DMVE 4797
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
+V AK Q VS+IDYR LH+W C PD +K D SD +YK DL WLKGIG
Sbjct: 4798 MVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCY 4857
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQISE 194
+ E++ K+A +L ++ Y K LK + + DTP +QA + Q+S+
Sbjct: 4858 VWDTPEILHAKHAYDLRDDIKY--KAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSD 4911
Score = 81.6 bits (200), Expect = 5e-16
Identities = 50/188 (26%), Positives = 88/188 (46%), Gaps = 9/188 (4%)
Query: 25 YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK----GIHNTPLDM 80
YK+ Y K G +G ++ DDPK + ++ AK QSDR YK+ YEK+K TP
Sbjct: 597 YKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ 656
Query: 81 MSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140
+ + D+ ++ L + + K SD YK++ E KG
Sbjct: 657 LDTQLKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKC 716
Query: 141 WLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
+ P+ + + + Y++ P+ KFT++ D+P ++QA++N Q+S++
Sbjct: 717 YFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDL----- 771
Query: 201 NFNVRHYG 208
N+ +H G
Sbjct: 772 NYKAKHEG 779
Score = 73.2 bits (178), Expect = 2e-13
Identities = 58/185 (31%), Positives = 91/185 (49%), Gaps = 20/185 (10%)
Query: 23 YKYKEGYR--KQLGHHMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKG-IHNT 76
+KYKE Y K G+ +G PK V +H ++ S+R Y++ Y K K IH T
Sbjct: 4983 FKYKEAYEHTKAYGYTLG-------PKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTT 5035
Query: 77 PLDMMSIVQAKKCQVLVSDIDYRNYLHQWT----CLPDQNDVIQAKKAYDLQSDNLYKSD 132
P D I Q KK Q VS++ Y++ + LP VI + D+ SD YK D
Sbjct: 5036 P-DTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKED 5094
Query: 133 LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAV 190
L+ LKG G + +++R ++ + L + LY K + K+ ++DTPE + +
Sbjct: 5095 LQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKT 5154
Query: 191 QISEV 195
+SE+
Sbjct: 5155 HLSEL 5159
Score = 72.4 bits (176), Expect = 3e-13
Identities = 66/231 (28%), Positives = 96/231 (41%), Gaps = 52/231 (22%)
Query: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79
V KYK Y K + + D P + A A SD YK+ ++K+KG ++T D
Sbjct: 5226 VSEKKYKIQYEKMKDK---YTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKD 5282
Query: 80 MMSIVQAKKCQVLVSDIDYR-NYLHQ---WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEW 135
+ IV +K +S I Y+ NY+ Q W +PD+ + + D SD YK DL W
Sbjct: 5283 ALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTW 5342
Query: 136 LKGIG------------------------------------WLPEGSVEVMRVKNAQNLL 159
LKGIG ++ + + K A L+
Sbjct: 5343 LKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPIN-RHFKYATQLM 5401
Query: 160 NERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEV------EKSRDNF 202
NE+ YR E K+ +VD P + AK QIS++ EKS+D F
Sbjct: 5402 NEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKF 5452
Score = 69.7 bits (169), Expect = 2e-12
Identities = 61/245 (24%), Positives = 111/245 (45%), Gaps = 54/245 (22%)
Query: 22 SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMM 81
SY+YK+ Y K GH + T+ D+ + + A ++QS +YK+ YEK +G +
Sbjct: 5864 SYQYKKKYEKSKGH---YHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETP 5920
Query: 82 SIVQAKKCQVLVSDIDYRN-------------------YLH------------------- 103
+ + AK+ Q + S +YR LH
Sbjct: 5921 TYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEE 5980
Query: 104 -----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWL---KGIGWLPEGSVEVMRVKNA 155
T + D D+++AK A + ++ YK DLE +G+ + + + MR +NA
Sbjct: 5981 SIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNA 6040
Query: 156 QNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEVEKSRDNF--NVRHYGSYL 211
++ ++ Y+ E K FTS+VDTPE+I A+ +S +K +++ ++ +Y + L
Sbjct: 6041 TDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQ-QVKNLSSQKKYKEDAEKSMSYYETVL 6099
Query: 212 DQKQL 216
D ++
Sbjct: 6100 DTPEI 6104
Score = 60.5 bits (145), Expect = 1e-09
Identities = 54/191 (28%), Positives = 88/191 (46%), Gaps = 26/191 (13%)
Query: 19 EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKGIHN 75
++ YK Y K G+ T+ D P +H K++ SD +YK+ Y+++K
Sbjct: 5470 QISDILYKLEYNK--AKPRGYTTIHDTPM---LLHVRKVKDEVSDLKYKEVYQRNKSNCT 5524
Query: 76 TPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKS 131
D + I AK + +++DY+ W PD+ D +QA K+ QSD YK
Sbjct: 5525 IEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKL 5584
Query: 132 DLEWLKGIGWLPEGSVEVMRVKNA----QNLLNERLYRIKPEALK----FTSIVDTPEVI 183
D E+LKG + V KN +N L E + K + +K ++ DTP+++
Sbjct: 5585 DREFLKGC------KLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQIL 5638
Query: 184 QAKINAVQISE 194
AK + +SE
Sbjct: 5639 LAKTVSNLVSE 5649
Score = 58.9 bits (141), Expect = 4e-09
Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 13/167 (7%)
Query: 41 TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN 100
++ DD +V A+ I+SD +YK+ + K +G + D I+ AK LVS+ Y++
Sbjct: 5595 SVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKD 5654
Query: 101 YLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-----IGWLPEGSVEV 149
++ + +T LP+ D + K+ SD YK KG I P
Sbjct: 5655 HVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHA 5714
Query: 150 MRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
M V Q+ + R + E L +T++ D P++ +A A Q SEVE
Sbjct: 5715 MEVAKKQSDVAYR--KDAKENLHYTTVADRPDIKKATQAAKQASEVE 5759
Score = 57.8 bits (138), Expect = 8e-09
Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 11/189 (5%)
Query: 24 KYKEGYRKQLGH-HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTP- 77
KYKE Y K G ++P+ A SD+ YK+ YEK+K TP
Sbjct: 347 KYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPK 406
Query: 78 LDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137
+ +++Q D ++ L + + K SD YK++ E +
Sbjct: 407 FKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDR 466
Query: 138 GIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEK 197
G G+ P+ + + + Y++ P+ KFT + D+P ++QA++N+ Q+S++
Sbjct: 467 GKGFFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDL-- 524
Query: 198 SRDNFNVRH 206
N+ +H
Sbjct: 525 ---NYKAKH 530
Score = 57.8 bits (138), Expect = 8e-09
Identities = 51/177 (28%), Positives = 84/177 (47%), Gaps = 15/177 (8%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYK+ + + F ++ D P+ + A + S ++YK+ EKS + T LD I
Sbjct: 6048 KYKQSAEMEKAN---FTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEI 6104
Query: 84 VQAKKCQ----VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139
+ ++ Q +L D +N + T + D ++++ K+ S LYK D+ I
Sbjct: 6105 QRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAI 6164
Query: 140 GWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL-KFTSIVDTPEVIQAKINAVQISEV 195
G P E+MRVK Q+ ++ Y+ EA+ + T I D PEV + K IS V
Sbjct: 6165 GKTP----EMMRVKQTQDHISSVKYK---EAIGQGTPIPDLPEVKRVKETQKHISSV 6214
Score = 52.8 bits (125), Expect = 3e-07
Identities = 51/183 (27%), Positives = 78/183 (42%), Gaps = 9/183 (4%)
Query: 19 EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78
++ KYKE Y QLG +R++ D P+ SD +YK+ KGI
Sbjct: 5295 DISKIKYKENYMSQLGI---WRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAY 5351
Query: 79 DMMSIVQAKKCQVLVSDIDYRNYLHQ----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134
D A+K + L S Y+ + + + D K A L ++ Y++D E
Sbjct: 5352 DTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYE 5411
Query: 135 WLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQI 192
K L + K A + +++ YR E KFTSIVDTPE ++ QI
Sbjct: 5412 QRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQI 5471
Query: 193 SEV 195
S++
Sbjct: 5472 SDI 5474
Score = 52.0 bits (123), Expect = 4e-07
Identities = 42/165 (25%), Positives = 79/165 (47%), Gaps = 7/165 (4%)
Query: 29 YRKQLGHHMGFRT-LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAK 87
Y++ L GF L D P V + H K+ S+ Y K + + LD + +
Sbjct: 5091 YKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQ 5150
Query: 88 KCQVLVSDIDYR----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
+ + +S++ YR +T +PD D+++AK+ LQS LY +
Sbjct: 5151 ELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAG 5210
Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAK 186
+ + K+ +++++E+ Y+I+ E + K+T + DTP +I+AK
Sbjct: 5211 NQTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAK 5255
Score = 51.2 bits (121), Expect = 8e-07
Identities = 55/208 (26%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Query: 25 YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIV 84
YK+ Y H ++ D P + A ++ QSD EYK E KG + D + V
Sbjct: 5547 YKKQYEANKAH---WKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTV 5603
Query: 85 QAKKCQVLVSDIDYR--NYLHQWTC--LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140
A + ++ SD+ Y+ + + TC +PD ++ AK +L S+N YK ++ G
Sbjct: 5604 LALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQG 5663
Query: 141 ---WLPEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQIS 193
LPE + + + VK +++ Y+ K K ++ +++ PEV A A + S
Sbjct: 5664 SYTTLPE-TRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQS 5722
Query: 194 EVEKSRDNFNVRHYGSYLDQKQLGPAQQ 221
+V +D HY + D+ + A Q
Sbjct: 5723 DVAYRKDAKENLHYTTVADRPDIKKATQ 5750
Score = 50.4 bits (119), Expect = 1e-06
Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 10/187 (5%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ-SDREYKKAYEKSKGIHNTPLDMMS 82
KYKE + K G T D + I + Q S+ +Y+ + +K I +
Sbjct: 100 KYKEKFEKTKGQPYASTT---DTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKD 156
Query: 83 IVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
I AKK VS + Y+ ++ PD +++QA K + S LY D E K
Sbjct: 157 IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKS 216
Query: 139 IGWLPEGSVEVMRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
+ + S E+ RV AQ L++ Y+ + + +FT + D P++ AK Q+S+ +
Sbjct: 217 LFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQK 276
Query: 197 KSRDNFN 203
D N
Sbjct: 277 YKEDYEN 283
Score = 50.1 bits (118), Expect = 2e-06
Identities = 56/205 (27%), Positives = 82/205 (40%), Gaps = 43/205 (20%)
Query: 44 DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYL 102
D P+ + A HA ++ D +YK K++ + D VQA K +SD Y +Y+
Sbjct: 4860 DTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYV 4919
Query: 103 H--QWTCLPDQN--DVIQAKKAYDLQSDNLYKSDLEWL---------------------- 136
H + P D+ +A AY LQS NLYK+ L L
Sbjct: 4920 HSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYM 4979
Query: 137 -------------KGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTP 180
K G+ L V + V+ N+ +ERLYR LK + DTP
Sbjct: 4980 SSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTP 5039
Query: 181 EVIQAKINAVQISEVEKSRDNFNVR 205
E+ Q K +SE+ D F ++
Sbjct: 5040 EIRQVKKTQEAVSELIYKSDFFKMQ 5064
Score = 48.1 bits (113), Expect = 6e-06
Identities = 48/175 (27%), Positives = 89/175 (50%), Gaps = 24/175 (13%)
Query: 51 AIHAAKIQSDREYKKAYEKSK--GIHNTPLDMMSIVQAKKCQVLVSDIDYR----NYLHQ 104
A A+ I ++++Y++ + K I + P+ VQ+K Q SDI Y+ +H+
Sbjct: 972 AKRASDILNEKKYRQHPDTLKFTSIEDAPIT----VQSKINQAQRSDIAYKAKGEEIIHK 1027
Query: 105 WTCLPDQNDVIQAK-KAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNER 162
+ PD IQAK AY++ S+N+YK+DL+ L G+ L ++ + K A+ ++
Sbjct: 1028 YNLPPDLPQFIQAKVNAYNI-SENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDV 1086
Query: 163 LY-----RIKPEALKFTSIVDTPEVIQ----AKINAVQ--ISEVEKSRDNFNVRH 206
Y + K + + F S+ D P+++ AKI + + + EK++ +N H
Sbjct: 1087 QYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPH 1141
Score = 47.8 bits (112), Expect = 8e-06
Identities = 45/184 (24%), Positives = 83/184 (45%), Gaps = 10/184 (5%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KY+ Y ++ + + D+P+ + A A S +Y+K YEKSK + +D
Sbjct: 5405 KYRADYEQRKDK---YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEH 5461
Query: 84 VQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
++ K +SDI Y+ ++ +T + D ++ +K D SD YK + K
Sbjct: 5462 LRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKS 5521
Query: 139 IGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEVE 196
+ +V + K+A + Y+ + EA K + D P+ +QA +++Q S+ E
Sbjct: 5522 NCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFE 5581
Query: 197 KSRD 200
D
Sbjct: 5582 YKLD 5585
Score = 47.0 bits (110), Expect = 1e-05
Identities = 50/191 (26%), Positives = 77/191 (40%), Gaps = 48/191 (25%)
Query: 56 KIQSDREYKKAY-EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN-------------- 100
+IQSD EYK+ Y E KG+ +P + + +AKK SD YR
Sbjct: 2161 RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM 2220
Query: 101 ----------------YLHQWT-------CLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137
Y W +PD D++QAK+ L S LYK E
Sbjct: 2221 DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL 2280
Query: 138 GIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK-------FTSIVDTPEVIQAKINA 189
G+ LP ++ V K ++++ ++ Y+ K K F S+ D P+++ + A
Sbjct: 2281 KKGYDLPVDAISVQLAKASRDIASD--YKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVA 2338
Query: 190 VQISEVEKSRD 200
SE E +D
Sbjct: 2339 KMQSEREYKKD 2349
Score = 47.0 bits (110), Expect = 1e-05
Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 7/159 (4%)
Query: 44 DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 103
D P+ + A + +QS +Y A +++ +N D V A + + S++ Y+ H
Sbjct: 4615 DTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYH 4674
Query: 104 Q----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNL 158
Q +T + + D + + +L S NLYK + +K + LP ++ + KN ++L
Sbjct: 4675 QIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHL 4734
Query: 159 LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEK 197
+ YR + E KF ++ P + N + V K
Sbjct: 4735 ASHIKYREEYE--KFKALYTLPRSVDDDPNTARCLRVGK 4771
Score = 46.6 bits (109), Expect = 2e-05
Identities = 53/202 (26%), Positives = 83/202 (41%), Gaps = 9/202 (4%)
Query: 19 EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78
EV + YRK ++ + T+ D P A AAK S+ EY+ + K + L
Sbjct: 5716 EVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSML 5775
Query: 79 DMMSIVQAKKCQVLVSDIDYR-NYLHQWTCLPDQNDVIQ-----AKKAYDLQSDNLYKSD 132
I AKK L S + YR N+ + P N K A +L S+ YK+D
Sbjct: 5776 GRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKAD 5835
Query: 133 LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAV 190
L+ L + S+ + V N L + Y+ K E K + +I D E + K A
Sbjct: 5836 LKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLK-EAT 5894
Query: 191 QISEVEKSRDNFNVRHYGSYLD 212
++ + K ++ + LD
Sbjct: 5895 ELQSIVKYKEKYEKERGKPMLD 5916
Score = 45.8 bits (107), Expect = 3e-05
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Query: 29 YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGI-HNTPLDMMSIVQAK 87
YRK TL + P A AA+I YK+ +E+ K + P D + V A
Sbjct: 4180 YRKDWNATKSKYTLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAH 4239
Query: 88 KCQVLVSDIDYR-NYLHQ---WTCLPDQND---VIQAKKAYDLQSDNLYKSDLEWLKGIG 140
C + S++ Y+ ++ Q + +P D ++ + A +Q++ LYK D K
Sbjct: 4240 HCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKI 4299
Query: 141 WLPEGSVEVMRVKNAQNLLNERLYR 165
+P V V+ K Q L+++ YR
Sbjct: 4300 NIPADMVSVLAAKQGQTLVSDIDYR 4324
Score = 44.3 bits (103), Expect = 9e-05
Identities = 42/158 (26%), Positives = 70/158 (44%), Gaps = 10/158 (6%)
Query: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
F ++ D V A H K SD YK EK K + ++ +QAK + +SD Y
Sbjct: 1481 FTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHY 1540
Query: 99 -----RNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150
+ + PD ++ AK + ++ SD YK E KG +G+L + +++
Sbjct: 1541 KADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLV 1600
Query: 151 RVKNAQNLLNERLYRIKPEA--LKFTSIVDTPEVIQAK 186
N + ++R Y+ EA K+ + +D V AK
Sbjct: 1601 HYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAK 1638
Score = 43.5 bits (101), Expect = 2e-04
Identities = 35/106 (33%), Positives = 53/106 (50%), Gaps = 7/106 (6%)
Query: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMSIVQAKKCQVLVSDID 97
+ TL D V A + AKI ++ YK+A+E K +H P D+ I+ AK + +SD
Sbjct: 1969 YSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP-DIPQIILAKANAINMSDKL 2027
Query: 98 YRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
Y+ L + + PD + AK + D+ SD YK + E KG
Sbjct: 2028 YKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKG 2073
Score = 43.1 bits (100), Expect = 2e-04
Identities = 41/155 (26%), Positives = 63/155 (40%), Gaps = 41/155 (26%)
Query: 52 IHAAK---IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN-------- 100
IHA K +QSD YK E KGI P+D + +V+AK+ L+SD YR
Sbjct: 3370 IHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFT 3429
Query: 101 ----------------------YLHQWT-------CLPDQNDVIQAKKAYDLQSDNLYKS 131
Y W +PD +++ AK SD LYK
Sbjct: 3430 SITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKL 3489
Query: 132 DLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
LE K G+ L ++ + K ++++ ++ Y+
Sbjct: 3490 ALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYK 3524
Score = 42.7 bits (99), Expect = 3e-04
Identities = 37/161 (22%), Positives = 69/161 (42%), Gaps = 9/161 (5%)
Query: 42 LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY 101
L D + A A +QSD YK E +GI P+ + + + K+ ++SD YR
Sbjct: 3606 LPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQP 3665
Query: 102 LHQ--WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLL 159
Q +TC+ D +++ AK S +LY + K + + +++ K+ +
Sbjct: 3666 ADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANI 3725
Query: 160 NERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
+++LY + K + +A+ I + SRD
Sbjct: 3726 SQKLYTKGWDESKMKD-------YDLRADAISIKSAKASRD 3759
Score = 42.0 bits (97), Expect = 5e-04
Identities = 46/217 (21%), Positives = 94/217 (43%), Gaps = 53/217 (24%)
Query: 29 YRKQLGHHMGFRTLQDDPKSV-WAIHAAKIQSDREYKKAYEK-SKGIHNTPLDMMSIVQA 86
YR+ H+ TL D +V + +A +IQSD YK + KGI P++ + + +A
Sbjct: 1649 YRQSYHHY----TLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKA 1704
Query: 87 KKCQVLVSDIDYRN------------------------------YLHQWT-------CLP 109
KK ++S+ YR Y +W +P
Sbjct: 1705 KKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMP 1764
Query: 110 DQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR--- 165
D D++ ++ SD LYK+ E K G+ L ++ + + ++++ ++ Y+
Sbjct: 1765 DTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAY 1824
Query: 166 --IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
K + + F S+ D P++ ++ +Q+++++ R+
Sbjct: 1825 EQAKGKHIGFRSLEDDPKL----VHFMQVAKMQSDRE 1857
Score = 42.0 bits (97), Expect = 5e-04
Identities = 46/206 (22%), Positives = 84/206 (40%), Gaps = 48/206 (23%)
Query: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAY-EKSKGIHNTPLDMMSIVQAKKCQVLVSDID 97
+ L D A + +IQSD +YK Y + KGI PL + + KK ++S+
Sbjct: 1900 YNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKK 1959
Query: 98 YRN------------------------------YLHQWTC-------LPDQNDVIQAKKA 120
YR Y W +PD +I AK
Sbjct: 1960 YRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKAN 2019
Query: 121 YDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRI-----KPEALKFT 174
SD LYK LE K G+ L ++ + K ++++ ++ Y+ K + + F
Sbjct: 2020 AINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFR 2079
Query: 175 SIVDTPEVIQAKINAVQISEVEKSRD 200
S+ D P++ ++++Q+++++ R+
Sbjct: 2080 SLEDDPKL----VHSMQVAKMQSDRE 2101
Score = 41.6 bits (96), Expect = 6e-04
Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 10/154 (6%)
Query: 42 LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY 101
+QD P+ + K S YK+ I TP +++ K+ Q +S + Y+
Sbjct: 6133 VQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTP----EMMRVKQTQDHISSVKYKEA 6188
Query: 102 LHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNE 161
+ Q T +PD +V + K+ S +YK +L G G + E+ RVK Q +
Sbjct: 6189 IGQGTPIPDLPEVKRVKETQKHISSVMYKENL----GTGIPTTVTPEIERVKRNQENFSS 6244
Query: 162 RLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195
LY K K TPE+ + K N S V
Sbjct: 6245 VLY--KENLGKGIPTPITPEMERVKRNQENFSSV 6276
Score = 40.0 bits (92), Expect = 0.002
Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 16/151 (10%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYK + L ++ FR++ D P+ V A + QSD +YK+ + K+KG + D I
Sbjct: 4388 KYK---KNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHI 4444
Query: 84 VQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
+K L S I Y+ + +T ++ AK A + S+ YK E KG
Sbjct: 4445 SHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKG 4504
Query: 139 -------IGWLPEGSVEVMRVKNAQNLLNER 162
IG P G V + + ++ LN R
Sbjct: 4505 HYLAGKVIGEFP-GVVHCLDFQKMRSALNYR 4534
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 7/123 (5%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
YKYKE + + F+ + D P + +A ++ ++++Y+ YE+ K ++ +D
Sbjct: 5369 YKYKEVFERTKSD---FKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPR 5425
Query: 83 IVQAKKCQVLVSDIDYR-NY---LHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
+ AK +S I YR NY ++T + D + ++ K SD LYK + K
Sbjct: 5426 HLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKP 5485
Query: 139 IGW 141
G+
Sbjct: 5486 RGY 5488
Score = 40.0 bits (92), Expect = 0.002
Identities = 41/152 (26%), Positives = 64/152 (42%), Gaps = 8/152 (5%)
Query: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHN--TP 77
V KYK+ +K L + TL + +V K SD YKK + K KG N
Sbjct: 5647 VSENKYKDHVKKHLAQG-SYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIM 5705
Query: 78 LDMMSIVQAKKCQVLVSDIDYR----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL 133
L+ + A + SD+ YR LH +T + D+ D+ +A +A S+ Y++
Sbjct: 5706 LEPPEVKHAMEVAKKQSDVAYRKDAKENLH-YTTVADRPDIKKATQAAKQASEVEYRAKH 5764
Query: 134 EWLKGIGWLPEGSVEVMRVKNAQNLLNERLYR 165
G G ++ K A L ++ YR
Sbjct: 5765 RKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYR 5796
Score = 39.3 bits (90), Expect = 0.003
Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 7/117 (5%)
Query: 54 AAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLP 109
A++I S+++Y++ +++K + D M IV AK SD YR Q +P
Sbjct: 2438 ASEIISEKKYRQPPDRNK--FTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMP 2495
Query: 110 DQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
D D++ AK SD LY+ E LK G+ LP ++ + K ++ + +E Y+
Sbjct: 2496 DTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYK 2552
Score = 38.9 bits (89), Expect = 0.004
Identities = 54/207 (26%), Positives = 85/207 (41%), Gaps = 17/207 (8%)
Query: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
F +++D P +V + +SD YK E+ +N P D+ +QAK +S+ Y
Sbjct: 993 FTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMY 1052
Query: 99 RNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150
+ L + D + AK A SD YK D E KG +G+ + +++
Sbjct: 1053 KADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLV 1112
Query: 151 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210
N + ++R Y K + K S +TP + N V + + N N +H S
Sbjct: 1113 HYMNVAKIQSDREY--KKDYEKTKSKYNTPHDM---FNVVAAKKAQDVVSNVNYKH--SL 1165
Query: 211 LDQKQLGPAQQWELSELSAMWTYPSDN 237
L A ELS+ M SDN
Sbjct: 1166 HHYTYLPDAMDLELSK--NMMQIQSDN 1190
Score = 37.7 bits (86), Expect = 0.009
Identities = 38/142 (26%), Positives = 59/142 (41%), Gaps = 8/142 (5%)
Query: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
F ++ D P V A K SD YK E K + D+ +QAK +SD+ Y
Sbjct: 1237 FTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCY 1296
Query: 99 RNYLHQW-----TCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150
+ H L D + AK + ++ SD YK E KG +G+ + +++
Sbjct: 1297 KRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLV 1356
Query: 151 RVKNAQNLLNERLYRIKPEALK 172
N L ++R Y+ E K
Sbjct: 1357 HYMNVAKLQSDREYKKNYENTK 1378
Score = 37.4 bits (85), Expect = 0.011
Identities = 56/207 (27%), Positives = 85/207 (41%), Gaps = 21/207 (10%)
Query: 5 CLFPKPHTYDLS----LPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60
C FP+ T + L + + YK K F + D P + A K SD
Sbjct: 716 CYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTK-----FTAVTDSPVLLQAQLNTKQLSD 770
Query: 61 REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY-----RNYLHQWTCLPDQNDVI 115
YK +E K + P D +Q + +SD Y ++ ++ D ++
Sbjct: 771 LNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLL 830
Query: 116 QAKKAYDLQSDNLYKSDLEWLKG--IGWLPEGSVEVM--RVKNAQNLLNERLYRIKPEAL 171
AK SD +YK D E KG IG L M +K A+N ++R YR E
Sbjct: 831 AAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKN-QSDREYRKDYEKS 889
Query: 172 K--FTSIVDTPEVIQAKINAVQISEVE 196
K +T+ +D +V QAK + S+V+
Sbjct: 890 KTIYTAPLDMLQVTQAKKSQAIASDVD 916
Score = 37.4 bits (85), Expect = 0.011
Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 10/168 (5%)
Query: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
+ + D P V A+ + S+ +YK+ Y + K + T L+ + + + + L S Y
Sbjct: 4645 YNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLY 4704
Query: 99 RNYLHQWTC----LPDQN-DVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP---EGSVEVM 150
+ + LP + AK L S Y+ + E K + LP +
Sbjct: 4705 KEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTA 4764
Query: 151 RVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
R L +RLYR + +K + D E++ AK + ++SE++
Sbjct: 4765 RCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEID 4812
Score = 36.2 bits (82), Expect = 0.025
Identities = 33/162 (20%), Positives = 65/162 (40%), Gaps = 38/162 (23%)
Query: 42 LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN- 100
L D + A A +QSD YK + +GI P+ M +V+ K+ ++SD YR
Sbjct: 3120 LPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQP 3179
Query: 101 -----------------------------YLHQWT-------CLPDQNDVIQAKKAYDLQ 124
Y W +PD +++ A++
Sbjct: 3180 PDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINY 3239
Query: 125 SDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
S++LY+ +E K G+ L ++ ++ K ++++ ++ Y+
Sbjct: 3240 SESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYK 3281
Score = 32.3 bits (72), Expect = 0.37
Identities = 44/154 (28%), Positives = 67/154 (43%), Gaps = 12/154 (7%)
Query: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
F + D P + A +K SD YK +E K + P D + +Q K +SD Y
Sbjct: 502 FTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLY 561
Query: 99 -----RNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLPEGSVEVM- 150
++ ++ D ++ AK SD +YK D E KG IG L M
Sbjct: 562 KQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKML 621
Query: 151 -RVKNAQNLLNERLYRIKPEALKFTSI--VDTPE 181
+K A+N ++RLY+ E K S+ +TP+
Sbjct: 622 HSLKVAKN-QSDRLYKENYEKTKAKSMNYCETPK 654
Score = 32.3 bits (72), Expect = 0.37
Identities = 39/161 (24%), Positives = 75/161 (46%), Gaps = 20/161 (12%)
Query: 13 YDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKG 72
YDL + YK + K +G M +L+D+ A +I SD Y++ ++ K
Sbjct: 2647 YDLQSDNL--YKSDLQWLKGIGW-MTSGSLEDEKNK----RATQILSDHVYRQHPDQFK- 2698
Query: 73 IHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWT-------CLPDQNDVIQAKKAYDLQS 125
++ +D + +V AK + ++ +R Y W +PD +V+ AK+ S
Sbjct: 2699 -FSSLMDSIPMVLAKNNAITMN---HRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYS 2754
Query: 126 DNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
+ LYK LE K G+ + ++ + K ++++ +E Y+
Sbjct: 2755 EKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYK 2795
Score = 30.0 bits (66), Expect = 1.8
Identities = 31/138 (22%), Positives = 59/138 (42%), Gaps = 5/138 (3%)
Query: 63 YKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYD 122
YK+ K+ TP + + K+ Q +S + Y+ L + T P ++ + K+ +
Sbjct: 6309 YKENVGKATATPVTP----EMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQE 6364
Query: 123 LQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEV 182
S LYK ++ PE +N ++L +R + + K ++DTPE+
Sbjct: 6365 NFSSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQG-KAAYVLDTPEM 6423
Query: 183 IQAKINAVQISEVEKSRD 200
+ + IS V+ D
Sbjct: 6424 RRVRETQRHISTVKYHED 6441
>gi|46049092 nebulin-related anchoring protein isoform C [Homo
sapiens]
Length = 1695
Score = 159 bits (401), Expect = 3e-39
Identities = 77/184 (41%), Positives = 118/184 (64%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYKE Y + G +G + +Q D + ++ +K+QS+ EYKK +E +K + LDM+ +
Sbjct: 786 KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 845
Query: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
V A+K Q L +D+ Y+ H +T LP V AKKAY LQSDN Y++D++W+KG+GW+
Sbjct: 846 VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 905
Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFN 203
GS+ V + K A L++E+ YR P+ALKFTSI DTPE++QA+I+ Q + N
Sbjct: 906 TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 965
Query: 204 VRHY 207
++H+
Sbjct: 966 IKHH 969
Score = 145 bits (365), Expect = 4e-35
Identities = 74/163 (45%), Positives = 106/163 (65%), Gaps = 4/163 (2%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYKE Y K G MG D + + ++ AK+ S+ EYKK +E+SK + P+DM++I
Sbjct: 547 KYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNI 602
Query: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
AKK Q L SD+DYR LH++T LP+ AKKAY LQS+ YK+DL W+KG+GWL
Sbjct: 603 RHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLT 662
Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAK 186
EGS+ + + K A L++E+ YR + + LKFTS+ D+ ++ AK
Sbjct: 663 EGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAK 705
Score = 142 bits (359), Expect = 2e-34
Identities = 69/169 (40%), Positives = 108/169 (63%)
Query: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79
+ YKYKE + K G +G R+L+DD +++A +QSD YKK +E SK + PLD
Sbjct: 1025 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1084
Query: 80 MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139
M ++V AKK Q L S+ DY++ L Q+T L + + AKKA+ LQS+NLY+SDL +++G+
Sbjct: 1085 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1144
Query: 140 GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKIN 188
+ G++E+ K A L++E YR P + K+T++ DTP ++ AK +
Sbjct: 1145 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFS 1193
Score = 130 bits (327), Expect = 1e-30
Identities = 67/186 (36%), Positives = 115/186 (61%), Gaps = 1/186 (0%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
+ Y+ + K+ G +G ++++DDP+ ++QS+ +Y++ S+ + P+DM+
Sbjct: 1271 FLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVH 1330
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
+V AK Q L SD DYR H++T LP+ + AKKA+ LQS+ YKSDL +KGIGWL
Sbjct: 1331 LVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWL 1390
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE-VEKSRDN 201
S ++ K A L++E YR KP+++KFT++VD+P+++ AK + + +E + +S D
Sbjct: 1391 ALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDA 1450
Query: 202 FNVRHY 207
++ Y
Sbjct: 1451 ESLHRY 1456
Score = 118 bits (296), Expect = 4e-27
Identities = 61/163 (37%), Positives = 92/163 (56%), Gaps = 12/163 (7%)
Query: 12 TYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQS 59
+YD L +P ++YKE + + G +G+R++ DDP+ ++ ++QS
Sbjct: 1491 SYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQS 1550
Query: 60 DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKK 119
D EYKK + KS+ ++ D ++QAK+ Q L SD+ YR L Q TC P+Q + A+K
Sbjct: 1551 DNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQK 1610
Query: 120 AYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNER 162
A+ LQSD YKSDL +G+GW P GS +V + A L N R
Sbjct: 1611 AHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1653
Score = 56.6 bits (135), Expect = 2e-08
Identities = 54/190 (28%), Positives = 90/190 (47%), Gaps = 15/190 (7%)
Query: 24 KYKEGYRKQLGHHMGFRTLQD--DPKSVWAIHAAKIQSDREYKKAYEKSKGI---HNTPL 78
+Y +GY ++ H G + P A A ++ SD +Y++ + K KG H+ P
Sbjct: 293 QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPA 352
Query: 79 -DMMSIVQAKKCQVLVSDIDYR-NYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSD 132
D + + QA+ LVS+ Y+ NY + ++ + + A K L S+ YK+D
Sbjct: 353 QDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKAD 412
Query: 133 LEWLKGIGWLPEGSVEVMRVKNAQNL--LNERLYRIKPEALKFTSIVDTPEVIQAKINAV 190
+ I + + A L L + YR + LK++S+ DTP+++QAKINA
Sbjct: 413 YK--HDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQ 470
Query: 191 QISEVEKSRD 200
Q+S V D
Sbjct: 471 QLSHVNYRAD 480
Score = 45.4 bits (106), Expect = 4e-05
Identities = 46/175 (26%), Positives = 75/175 (42%), Gaps = 41/175 (23%)
Query: 29 YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKK 88
YRK+L + L +D K+ WA A +QS+ +YK KG+ +++ QAKK
Sbjct: 617 YRKKLHE---YTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 673
Query: 89 CQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQS--------------------- 125
LVS+ +YR + + +T + D + + AKK+ +LQS
Sbjct: 674 AGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 733
Query: 126 --------------DNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
+ LYKS E K G+ L S+ + K ++L +E Y+
Sbjct: 734 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 788
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 8/132 (6%)
Query: 12 TYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK 71
+Y ++ VP K+ +Q + + ++ D P+ V A A+ S Y+ YEK+K
Sbjct: 429 SYQTAMKLVP---LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 485
Query: 72 GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSD 126
+ P D+ +V+AK L S++ Y+ + + D ++ AK + +L S+
Sbjct: 486 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 545
Query: 127 NLYKSDLEWLKG 138
YK + E KG
Sbjct: 546 IKYKEEYEKTKG 557
Score = 38.9 bits (89), Expect = 0.004
Identities = 55/242 (22%), Positives = 94/242 (38%), Gaps = 45/242 (18%)
Query: 10 PHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 69
P T ++ + S E +Q H + + D P + A + +I ++R YK A E
Sbjct: 1149 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGED 1208
Query: 70 SKGIHNTPLDMMSIVQAKKCQVLVSDIDY----RNYLHQWTCLPDQNDVIQAKKAY-DLQ 124
++ + L + ++AK +SD Y RN Q L + QA +A D+
Sbjct: 1209 ARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIA 1268
Query: 125 SDNLYK--------------------------------SDLEWLKGIG------WLPEGS 146
SD LY+ S+L++ +G LP
Sbjct: 1269 SDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1328
Query: 147 VEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRH 206
V ++ KNAQ L ++ YR + KFT++ + ++ AK SE+ D ++
Sbjct: 1329 VHLVHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKG 1386
Query: 207 YG 208
G
Sbjct: 1387 IG 1388
Score = 38.1 bits (87), Expect = 0.007
Identities = 42/180 (23%), Positives = 72/180 (40%), Gaps = 39/180 (21%)
Query: 20 VPSYKYKEGYRKQL-GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78
V KYKE Y+ + G + G D +++ A+ + S+ YK Y+ +N P
Sbjct: 368 VSENKYKENYQNHMRGRYEGVGM---DRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPA 424
Query: 79 DMMSIVQAKKCQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWL 136
+ Q V + D +YR + + ++ + D ++QAK S Y++D E
Sbjct: 425 TLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYE-- 482
Query: 137 KGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
+N LN +T D P++++AK NA SEV+
Sbjct: 483 -------------------KNKLN------------YTLPQDVPQLVKAKTNAKLFSEVK 511
Score = 37.7 bits (86), Expect = 0.009
Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
+YK G+ +++ F T+ D P+ + + A++QSD Y + YE+ +G + P +
Sbjct: 192 EYKRGHDERISR---FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248
Query: 84 VQ-AKKCQVLVSDIDY 98
Q AK+ L SD+ Y
Sbjct: 249 YQIAKRANELASDVRY 264
Score = 37.0 bits (84), Expect = 0.015
Identities = 36/149 (24%), Positives = 52/149 (34%), Gaps = 44/149 (29%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
+ Y+ Y K F L +D K WA A +QS+ YK KGI L
Sbjct: 1344 HDYRTQYHK-------FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1396
Query: 83 IVQAKKCQVLVSDIDYRNY-------------------------------------LHQW 105
+ AKK L+S+ YR LH++
Sbjct: 1397 MESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRY 1456
Query: 106 TCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134
T +PD D +A+ SD +Y++ E
Sbjct: 1457 TLIPDHPDFTRARLNALHLSDKVYRNSWE 1485
Score = 35.4 bits (80), Expect = 0.043
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 9/108 (8%)
Query: 108 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 164
LPD V ++A+K+ + Y D E +G G P R K A L ++ Y
Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193
Query: 165 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210
+ + +F+++VDTPE++++K A S+V + D R GS+
Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF 241
Score = 31.2 bits (69), Expect = 0.82
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 9/119 (7%)
Query: 60 DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDV 114
D Y+++ +K K +++ D IVQAK +S ++YR N L+ +T D +
Sbjct: 441 DANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLN-YTLPQDVPQL 497
Query: 115 IQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK 172
++AK L S+ YK E KG G+ + ++ ++ K + L + Y+ + E K
Sbjct: 498 VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 556
>gi|46049105 nebulin-related anchoring protein isoform S [Homo
sapiens]
Length = 1730
Score = 159 bits (401), Expect = 3e-39
Identities = 77/184 (41%), Positives = 118/184 (64%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYKE Y + G +G + +Q D + ++ +K+QS+ EYKK +E +K + LDM+ +
Sbjct: 821 KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 880
Query: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
V A+K Q L +D+ Y+ H +T LP V AKKAY LQSDN Y++D++W+KG+GW+
Sbjct: 881 VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 940
Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFN 203
GS+ V + K A L++E+ YR P+ALKFTSI DTPE++QA+I+ Q + N
Sbjct: 941 TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 1000
Query: 204 VRHY 207
++H+
Sbjct: 1001 IKHH 1004
Score = 145 bits (365), Expect = 4e-35
Identities = 74/163 (45%), Positives = 106/163 (65%), Gaps = 4/163 (2%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYKE Y K G MG D + + ++ AK+ S+ EYKK +E+SK + P+DM++I
Sbjct: 582 KYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNI 637
Query: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
AKK Q L SD+DYR LH++T LP+ AKKAY LQS+ YK+DL W+KG+GWL
Sbjct: 638 RHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLT 697
Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAK 186
EGS+ + + K A L++E+ YR + + LKFTS+ D+ ++ AK
Sbjct: 698 EGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAK 740
Score = 142 bits (359), Expect = 2e-34
Identities = 69/169 (40%), Positives = 108/169 (63%)
Query: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79
+ YKYKE + K G +G R+L+DD +++A +QSD YKK +E SK + PLD
Sbjct: 1060 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1119
Query: 80 MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139
M ++V AKK Q L S+ DY++ L Q+T L + + AKKA+ LQS+NLY+SDL +++G+
Sbjct: 1120 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1179
Query: 140 GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKIN 188
+ G++E+ K A L++E YR P + K+T++ DTP ++ AK +
Sbjct: 1180 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFS 1228
Score = 130 bits (327), Expect = 1e-30
Identities = 67/186 (36%), Positives = 115/186 (61%), Gaps = 1/186 (0%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
+ Y+ + K+ G +G ++++DDP+ ++QS+ +Y++ S+ + P+DM+
Sbjct: 1306 FLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVH 1365
Query: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142
+V AK Q L SD DYR H++T LP+ + AKKA+ LQS+ YKSDL +KGIGWL
Sbjct: 1366 LVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWL 1425
Query: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE-VEKSRDN 201
S ++ K A L++E YR KP+++KFT++VD+P+++ AK + + +E + +S D
Sbjct: 1426 ALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDA 1485
Query: 202 FNVRHY 207
++ Y
Sbjct: 1486 ESLHRY 1491
Score = 118 bits (296), Expect = 4e-27
Identities = 61/163 (37%), Positives = 92/163 (56%), Gaps = 12/163 (7%)
Query: 12 TYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQS 59
+YD L +P ++YKE + + G +G+R++ DDP+ ++ ++QS
Sbjct: 1526 SYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQS 1585
Query: 60 DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKK 119
D EYKK + KS+ ++ D ++QAK+ Q L SD+ YR L Q TC P+Q + A+K
Sbjct: 1586 DNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQK 1645
Query: 120 AYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNER 162
A+ LQSD YKSDL +G+GW P GS +V + A L N R
Sbjct: 1646 AHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1688
Score = 53.9 bits (128), Expect = 1e-07
Identities = 52/185 (28%), Positives = 80/185 (43%), Gaps = 10/185 (5%)
Query: 24 KYKEGYRKQLGH-HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
KY++ + K G H QD+ A K+ S+ EYKK E S+G +
Sbjct: 333 KYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQ 392
Query: 83 IVQAKKCQVLVSDIDYR-NYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137
K SD Y+ NY + ++ + + A K L S+ YK+D +
Sbjct: 393 FRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYK--H 450
Query: 138 GIGWLPEGSVEVMRVKNAQNL--LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195
I + + A L L + YR + LK++S+ DTP+++QAKINA Q+S V
Sbjct: 451 DIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHV 510
Query: 196 EKSRD 200
D
Sbjct: 511 NYRAD 515
Score = 45.4 bits (106), Expect = 4e-05
Identities = 46/175 (26%), Positives = 75/175 (42%), Gaps = 41/175 (23%)
Query: 29 YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKK 88
YRK+L + L +D K+ WA A +QS+ +YK KG+ +++ QAKK
Sbjct: 652 YRKKLHE---YTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 708
Query: 89 CQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQS--------------------- 125
LVS+ +YR + + +T + D + + AKK+ +LQS
Sbjct: 709 AGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 768
Query: 126 --------------DNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165
+ LYKS E K G+ L S+ + K ++L +E Y+
Sbjct: 769 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 823
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 8/132 (6%)
Query: 12 TYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK 71
+Y ++ VP K+ +Q + + ++ D P+ V A A+ S Y+ YEK+K
Sbjct: 464 SYQTAMKLVP---LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 520
Query: 72 GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSD 126
+ P D+ +V+AK L S++ Y+ + + D ++ AK + +L S+
Sbjct: 521 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 580
Query: 127 NLYKSDLEWLKG 138
YK + E KG
Sbjct: 581 IKYKEEYEKTKG 592
Score = 38.9 bits (89), Expect = 0.004
Identities = 55/242 (22%), Positives = 94/242 (38%), Gaps = 45/242 (18%)
Query: 10 PHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 69
P T ++ + S E +Q H + + D P + A + +I ++R YK A E
Sbjct: 1184 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGED 1243
Query: 70 SKGIHNTPLDMMSIVQAKKCQVLVSDIDY----RNYLHQWTCLPDQNDVIQAKKAY-DLQ 124
++ + L + ++AK +SD Y RN Q L + QA +A D+
Sbjct: 1244 ARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIA 1303
Query: 125 SDNLYK--------------------------------SDLEWLKGIG------WLPEGS 146
SD LY+ S+L++ +G LP
Sbjct: 1304 SDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1363
Query: 147 VEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRH 206
V ++ KNAQ L ++ YR + KFT++ + ++ AK SE+ D ++
Sbjct: 1364 VHLVHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKG 1421
Query: 207 YG 208
G
Sbjct: 1422 IG 1423
Score = 37.7 bits (86), Expect = 0.009
Identities = 52/234 (22%), Positives = 102/234 (43%), Gaps = 52/234 (22%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
+YK G+ +++ F T+ D P+ + + A++QSD Y + YE+ +G + P +
Sbjct: 192 EYKRGHDERISR---FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248
Query: 84 VQ-AKKCQVLVSDIDY-RNYLHQWTCL-----------------------PDQNDVIQ-- 116
Q AK+ L SD+ Y + Y + + P++ + +
Sbjct: 249 YQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGK 308
Query: 117 -------------AKKAYDLQSDNLYKSDLEWLKGIGW---LP-EGSVEVMRVKNAQNLL 159
AKKA++L SD Y+ D +KG LP + ++ + + ++ L+
Sbjct: 309 GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLV 368
Query: 160 NERLYRIKPEALKFTSI--VDTPEVIQ-AKINAVQISEVEKSRDNFNVRHYGSY 210
+E Y+ E+ + SI +TP+ +KI+ + + K ++N+ G Y
Sbjct: 369 SEVEYKKDLESSRGHSINYCETPQFRNVSKIS--KFTSDNKYKENYQNHMRGRY 420
Score = 37.7 bits (86), Expect = 0.009
Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 39/176 (22%)
Query: 24 KYKEGYRKQL-GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
KYKE Y+ + G + G D +++ A+ + S+ YK Y+ +N P +
Sbjct: 407 KYKENYQNHMRGRYEGVGM---DRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTP 463
Query: 83 IVQAKKCQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140
Q V + D +YR + + ++ + D ++QAK S Y++D E
Sbjct: 464 SYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYE------ 517
Query: 141 WLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
+N LN +T D P++++AK NA SEV+
Sbjct: 518 ---------------KNKLN------------YTLPQDVPQLVKAKTNAKLFSEVK 546
Score = 37.0 bits (84), Expect = 0.015
Identities = 36/149 (24%), Positives = 52/149 (34%), Gaps = 44/149 (29%)
Query: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82
+ Y+ Y K F L +D K WA A +QS+ YK KGI L
Sbjct: 1379 HDYRTQYHK-------FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1431
Query: 83 IVQAKKCQVLVSDIDYRNY-------------------------------------LHQW 105
+ AKK L+S+ YR LH++
Sbjct: 1432 MESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRY 1491
Query: 106 TCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134
T +PD D +A+ SD +Y++ E
Sbjct: 1492 TLIPDHPDFTRARLNALHLSDKVYRNSWE 1520
Score = 35.4 bits (80), Expect = 0.043
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 9/108 (8%)
Query: 108 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 164
LPD V ++A+K+ + Y D E +G G P R K A L ++ Y
Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193
Query: 165 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210
+ + +F+++VDTPE++++K A S+V + D R GS+
Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF 241
Score = 31.2 bits (69), Expect = 0.82
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 9/119 (7%)
Query: 60 DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDV 114
D Y+++ +K K +++ D IVQAK +S ++YR N L+ +T D +
Sbjct: 476 DANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLN-YTLPQDVPQL 532
Query: 115 IQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK 172
++AK L S+ YK E KG G+ + ++ ++ K + L + Y+ + E K
Sbjct: 533 VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591
>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
Length = 1014
Score = 62.4 bits (150), Expect = 3e-10
Identities = 49/158 (31%), Positives = 79/158 (50%), Gaps = 14/158 (8%)
Query: 51 AIHAAKIQSDREYKKAYE---KSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ--- 104
A A+++ S++EYKK E K KG+ D + + AKK + S+ DY+ L
Sbjct: 437 AKRASEMASEKEYKKDLESIIKGKGMQ-AGTDTLEMQHAKKAAEIASEKDYKRDLETEIK 495
Query: 105 ---WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSV-EVMRVKNAQNLL 159
D DV +AKKA ++ S YK DLE +KG G + +++R K +
Sbjct: 496 GKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIY 555
Query: 160 NERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEV 195
++R Y+ + E + +++I DTPE+ + K IS V
Sbjct: 556 SQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAV 593
Score = 55.1 bits (131), Expect = 5e-08
Identities = 46/171 (26%), Positives = 78/171 (45%), Gaps = 9/171 (5%)
Query: 29 YRKQLGHHM---GFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQ 85
Y+K L + + G + D P + A ++I S R+YK EK ++T D I +
Sbjct: 523 YKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQR 582
Query: 86 AKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEG 145
K Q +S + Y+ + T + D ++ + KK S YK +++ I PE
Sbjct: 583 IKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHATAISDPPE- 641
Query: 146 SVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196
+ RVK Q ++ Y K + K T + TPE+ + + N Q+S V+
Sbjct: 642 ---LKRVKENQKNISNLQY--KEQNYKATPVSMTPEIERVRRNQEQLSAVK 687
Score = 53.9 bits (128), Expect = 1e-07
Identities = 46/162 (28%), Positives = 81/162 (50%), Gaps = 15/162 (9%)
Query: 52 IHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLP-- 109
+ A+K+ S REYKK +E++KG+++ D + + K VL S + Y+ + P
Sbjct: 293 LKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPML 352
Query: 110 ---DQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLP-EGSVEVMRVKNAQNLLNERLY 164
+ +K+A +QS+ +YK D E +KG L + + E + VK NLL E+ Y
Sbjct: 353 EFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEY 412
Query: 165 R------IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
+ IK + ++ S + ++ +AK + SE E +D
Sbjct: 413 KKDLENEIKGKGMELNS--EVLDIQRAKRASEMASEKEYKKD 452
Score = 48.5 bits (114), Expect = 5e-06
Identities = 52/193 (26%), Positives = 91/193 (47%), Gaps = 20/193 (10%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKS-KGIHNTPLDMM- 81
KYKE Y K G M + P + A K+QS++ YK+ +EK KG + LD
Sbjct: 338 KYKEEYEKNKGKPM--LEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTP 395
Query: 82 SIVQAKKCQVLVSDIDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE- 134
+ K L+ + +Y+ L + D+ +AK+A ++ S+ YK DLE
Sbjct: 396 EFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLES 455
Query: 135 WLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR------IKPEALKFTSIVDTPEVIQAKI 187
+KG G ++E+ K A + +E+ Y+ IK + ++ ++ DT +V +AK
Sbjct: 456 IIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVST--DTLDVQRAKK 513
Query: 188 NAVQISEVEKSRD 200
+ S+ + +D
Sbjct: 514 ASEMASQKQYKKD 526
Score = 46.2 bits (108), Expect = 2e-05
Identities = 46/172 (26%), Positives = 71/172 (41%), Gaps = 13/172 (7%)
Query: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83
KYK+ K L + + T+ D P+ I K Y+K G D I
Sbjct: 559 KYKDEAEKMLSN---YSTIADTPE----IQRIKTTQQNISAVFYKKEVGAGTAVKDSPEI 611
Query: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143
+ KK Q +S + Y+ + T + D ++ + K+ S+ YK + P
Sbjct: 612 ERVKKNQQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTP 671
Query: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195
E+ RV+ Q L+ Y K E + T+I D PE+ +AK N IS V
Sbjct: 672 ----EIERVRRNQEQLSAVKY--KGELQRGTAISDPPELKRAKENQKNISNV 717
Score = 39.7 bits (91), Expect = 0.002
Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 7/136 (5%)
Query: 62 EYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAY 121
+YK ++ I + P + +AK+ Q +S++ YR L + T L ++ + KK
Sbjct: 687 KYKGELQRGTAISDPP----ELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQ 742
Query: 122 DLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK---FTSIVD 178
+ S Y D + +KG L + + VK AQN ++ Y E K FT +VD
Sbjct: 743 ENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVD 802
Query: 179 TPEVIQAKINAVQISE 194
P + + N +S+
Sbjct: 803 DPVTERVRKNTQVVSD 818
Score = 29.3 bits (64), Expect = 3.1
Identities = 48/189 (25%), Positives = 77/189 (40%), Gaps = 14/189 (7%)
Query: 19 EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKA---YEKSKGIHN 75
EV ++ YRK + + D P A +KI S+ EYKK K +
Sbjct: 153 EVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIG 212
Query: 76 TPLDMMSIVQAKKCQVLVS-----DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYK 130
P D V+A K + D + ++ H + L + Q + A L S+ YK
Sbjct: 213 RP-DFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPL-ESASFRQNQLAATLASNVKYK 270
Query: 131 SDLEWLKG-IGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKI 187
D++ + + LP + + V A +L+ R Y+ E K + D E + K
Sbjct: 271 KDIQNMHDPVSDLP-NLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKG 329
Query: 188 NAVQISEVE 196
NAV S+V+
Sbjct: 330 NAVLQSQVK 338
Score = 28.5 bits (62), Expect = 5.3
Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 12/165 (7%)
Query: 68 EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYL----HQWTCLPDQNDVIQAKKAYDL 123
E+ + + ++ +S+ A+KC L+SDI Y+ + T + D + K
Sbjct: 24 EEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAF 83
Query: 124 QSDNLYKSDL--EWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIV 177
S+ YK + + + +++ + L +E Y+ K +A K + +
Sbjct: 84 ISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMK 143
Query: 178 DTPEVIQA-KINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQ 221
+ PEV A ++N Q S + +D + Y + LD+ + A Q
Sbjct: 144 EPPEVKHAMEVNKHQ-SNISYRKDVQDTHTYSAELDRPDIKMATQ 187
Score = 28.1 bits (61), Expect = 6.9
Identities = 23/106 (21%), Positives = 43/106 (40%), Gaps = 6/106 (5%)
Query: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98
++ + +D A ++ SD YK+ ++KSK D + K +S+ Y
Sbjct: 30 YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89
Query: 99 RNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138
+ + + +P D + A + LQS+ YK + KG
Sbjct: 90 KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG 135
>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
Length = 270
Score = 37.4 bits (85), Expect = 0.011
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Query: 105 WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERL 163
+T + D + ++ K+ +LQS YK D E KG G+ + + E+ R+K Q ++
Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
Query: 164 YRIKPEALK---FTSIVDTPEVIQAKINAVQISE 194
Y E K FT +VD P + + N +S+
Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSD 155
Score = 33.9 bits (76), Expect = 0.13
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 6/98 (6%)
Query: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGI-HNTPLDMMSIVQAKKCQVLVSDID 97
F T+ D P+++ +++QS +YK+ +E+SKG + D + + K+ Q +S++
Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121
Query: 98 YRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYK 130
Y + +T + D + +K + SD YK
Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159
Score = 27.7 bits (60), Expect = 9.0
Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Query: 153 KNAQNLLNERLYRIKPEA------LKFTSIVDTPEVIQAKINAVQISEVEKSRD 200
K A N+ N + Y KP FT++ DTPE ++ K + S+V+ RD
Sbjct: 36 KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRD 89
>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
Length = 261
Score = 36.6 bits (83), Expect = 0.019
Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 3/134 (2%)
Query: 2 HLSCLFPKPHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDR 61
H +C + L++ Y+ K+ Y F + D P+++ +++QS
Sbjct: 26 HKACFHCETCKMTLNMKNYKGYE-KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQV 84
Query: 62 EYKKAYEKSKGI-HNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120
YK+ +EK+KG + D + + KK Q +S+I Y + P + ++ ++
Sbjct: 85 RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144
Query: 121 YDLQSDNLYKSDLE 134
D Q + Y+ LE
Sbjct: 145 -DSQDGSSYRRPLE 157
Score = 28.5 bits (62), Expect = 5.3
Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 105 WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERL 163
+T + D + ++ K+ +LQS YK + E KG G+ + + E+ R+K Q+ ++
Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121
Query: 164 Y 164
Y
Sbjct: 122 Y 122
>gi|127138957 zinc finger protein 537 [Homo sapiens]
Length = 1081
Score = 30.4 bits (67), Expect = 1.4
Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 147 VEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRH 206
VE LL+E++ + A FTS +TP I K+N EV+K + + +
Sbjct: 426 VETPVTPTITTLLDEKVQSVPLAATTFTSPSNTPASISPKLNVEVKKEVDKEKAVTDEK- 484
Query: 207 YGSYLDQKQLGPAQQWELSELSAMWTYPSDN 237
+++ P ++ E ++S+ + Y ++N
Sbjct: 485 -----PKQKDKPGEEEEKCDISSKYHYLTEN 510
>gi|222352158 carboxypeptidase 3, cytosolic [Homo sapiens]
Length = 920
Score = 29.6 bits (65), Expect = 2.4
Identities = 20/75 (26%), Positives = 31/75 (41%), Gaps = 17/75 (22%)
Query: 172 KFTSIVDTPEVIQ---------AKINAVQISEVEKSRDNFNVRHYGSYLDQKQLGPAQQW 222
K IV T E++Q + QI ++ R NF ++H QL PA
Sbjct: 737 KDKGIVQTQEILQYLLPIVHSTKNMQTTQIKQLFNPRTNFQIQH--------QLNPATCR 788
Query: 223 ELSELSAMWTYPSDN 237
+ + S WT P ++
Sbjct: 789 NIKKYSTSWTAPRNH 803
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 29.6 bits (65), Expect = 2.4
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 91 VLVSDIDYRNYL--HQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVE 148
V + DI+ RN + H+WT + + K L + + D +L G+ W G E
Sbjct: 560 VYLGDINSRNMIRTHEWT----HHQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDE 615
Query: 149 VMRVKNAQNLLNERLYRIK 167
R+KN +LL + L K
Sbjct: 616 AHRLKNDDSLLYKTLIDFK 634
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 28.9 bits (63), Expect = 4.1
Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)
Query: 8 PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
PKPH Y +P Y+YK Y KQ G
Sbjct: 1109 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1137
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 28.9 bits (63), Expect = 4.1
Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)
Query: 8 PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
PKPH Y +P Y+YK Y KQ G
Sbjct: 1109 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1137
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 28.9 bits (63), Expect = 4.1
Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)
Query: 8 PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
PKPH Y +P Y+YK Y KQ G
Sbjct: 1063 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1091
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 28.9 bits (63), Expect = 4.1
Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)
Query: 8 PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
PKPH Y +P Y+YK Y KQ G
Sbjct: 1063 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1091
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 28.9 bits (63), Expect = 4.1
Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 2/29 (6%)
Query: 8 PKPHTY--DLSLPEVPSYKYKEGYRKQLG 34
PKPH Y +P Y+YK Y KQ G
Sbjct: 1063 PKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1091
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 28.5 bits (62), Expect = 5.3
Identities = 34/159 (21%), Positives = 69/159 (43%), Gaps = 16/159 (10%)
Query: 58 QSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQA 117
Q +E K+ YE ++ N S V+ + CQ+ H+ C+ Q D +
Sbjct: 294 QQIKEMKEMYENAEAKVNNSTGKWSCVEERICQL----------QHENPCIEQQLDDVHQ 343
Query: 118 KKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIV 177
K+ + N+ + +E K L E + ++M N + L E L++ + E + +V
Sbjct: 344 KEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLM---NECDHLKESLFQYEREKAERVVVV 400
Query: 178 DTPEVIQAKINAVQISEVEKSRDNFNVRHYGSYLDQKQL 216
+ +A + +++ +E + + HY LD+ Q+
Sbjct: 401 RQLQQ-EAADSLKKLTMLESPLE--GISHYHINLDETQV 436
>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
Length = 1844
Score = 28.5 bits (62), Expect = 5.3
Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 15/107 (14%)
Query: 76 TPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEW 135
TPL+M S V+ KK + V N HQ + +N+ + D + D +D
Sbjct: 100 TPLEMFSNVEFKKKRKRV------NLSHQLNNIKTENEAPIEISSDDSKEDYSLNNDFV- 152
Query: 136 LKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEV 182
E S V+R K +L E + K + TS+ ++ +V
Sbjct: 153 --------ESSTSVLRYKKQVEVLAENIQDTKSQPNTMTSLQNSKKV 191
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 28.5 bits (62), Expect = 5.3
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 7/76 (9%)
Query: 53 HAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAK-KCQVLVSDIDYRNYLHQWTCLPDQ 111
H AKI+S EY ++ E K D +S AK + Q V ++ ++ PD
Sbjct: 636 HEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKE------PDT 689
Query: 112 NDVIQAKKAYDLQSDN 127
D + KKA +LQ ++
Sbjct: 690 QDADEVKKALELQMES 705
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 28.5 bits (62), Expect = 5.3
Identities = 36/160 (22%), Positives = 79/160 (49%), Gaps = 17/160 (10%)
Query: 75 NTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQA-KKAYDLQSD-NLYKSD 132
N L +++Q + C+ L SD++ +N L + + ++ +A +K Y+L+ + YK D
Sbjct: 307 NKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTI----ELTRACQKQYELEQELAFYKID 362
Query: 133 LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQI 192
++ + + + P E+ + + + + Y+ A + + I+D+ + +Q K ++
Sbjct: 363 AKF-EPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATE-SYIIDSAQAVQIK----KM 416
Query: 193 SEVEKSR-DNFNVRHY----GSYLDQKQLGPAQQWELSEL 227
E+ R D+ N+R + D+++ A Q LSEL
Sbjct: 417 EPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSEL 456
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 27.7 bits (60), Expect = 9.0
Identities = 11/34 (32%), Positives = 18/34 (52%)
Query: 21 PSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHA 54
P Y EG GHH+ + QD+ + +W +H+
Sbjct: 20 PFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHS 53
>gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]
Length = 600
Score = 27.7 bits (60), Expect = 9.0
Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 143 PEGSVEV-MRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201
P+GSV V +R +N + +Y EA+ +T +++Q +++ + +VE D
Sbjct: 41 PDGSVPVGLRQRNQTEKQSTGVYN--REAMLNFCEKETKKLMQREMSMDESKQVETKTDA 98
Query: 202 FNVRHYGSYLDQKQLGPAQQWELSE 226
N G +K LGP + +L +
Sbjct: 99 KNGEERGRDASKKALGPRRDSDLGK 123
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,292,605
Number of Sequences: 37866
Number of extensions: 378514
Number of successful extensions: 1193
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 876
Number of HSP's gapped (non-prelim): 155
length of query: 237
length of database: 18,247,518
effective HSP length: 99
effective length of query: 138
effective length of database: 14,498,784
effective search space: 2000832192
effective search space used: 2000832192
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.