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Search of human proteins with 117553586
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
(1870 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens] 3735 0.0
gi|4503355 dedicator of cytokinesis 1 [Homo sapiens] 2366 0.0
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens] 1940 0.0
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] 1152 0.0
gi|31415870 dedicator of cytokinesis 3 [Homo sapiens] 1144 0.0
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 86 4e-16
gi|145699123 dedicator of cytokinesis 11 [Homo sapiens] 71 9e-12
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens] 69 4e-11
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens] 69 4e-11
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens] 67 1e-10
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 60 2e-08
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 60 2e-08
gi|157426887 dedicator of cytokinesis 6 [Homo sapiens] 56 4e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 55 5e-07
gi|157168329 formin 1 [Homo sapiens] 54 1e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 1e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 54 1e-06
gi|18959210 WIRE protein [Homo sapiens] 54 1e-06
gi|4758666 LATS homolog 1 [Homo sapiens] 54 2e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 53 3e-06
gi|54112429 dedicator of cytokinesis 7 [Homo sapiens] 52 7e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is... 50 3e-05
gi|153792074 proline rich 12 [Homo sapiens] 49 4e-05
gi|116284392 mucin 2 precursor [Homo sapiens] 49 5e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 49 5e-05
gi|112421108 capicua homolog [Homo sapiens] 48 1e-04
gi|33356148 formin-like 1 [Homo sapiens] 48 1e-04
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 47 1e-04
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 47 1e-04
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 47 1e-04
>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
Length = 1870
Score = 3735 bits (9686), Expect = 0.0
Identities = 1870/1870 (100%), Positives = 1870/1870 (100%)
Query: 1 MARWIPTKRQKYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIFP 60
MARWIPTKRQKYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIFP
Sbjct: 1 MARWIPTKRQKYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIFP 60
Query: 61 ETYIHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQM 120
ETYIHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQM
Sbjct: 61 ETYIHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQM 120
Query: 121 TYSLIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETST 180
TYSLIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETST
Sbjct: 121 TYSLIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETST 180
Query: 181 IALFKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVCNIGEDAE 240
IALFKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVCNIGEDAE
Sbjct: 181 IALFKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVCNIGEDAE 240
Query: 241 LFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQI 300
LFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQI
Sbjct: 241 LFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQI 300
Query: 301 VRVGHMELKEGKKHTCGLRRPFGVAVMDITDIIHGKVDDEEKQHFIPFQQIAMETYIRQR 360
VRVGHMELKEGKKHTCGLRRPFGVAVMDITDIIHGKVDDEEKQHFIPFQQIAMETYIRQR
Sbjct: 301 VRVGHMELKEGKKHTCGLRRPFGVAVMDITDIIHGKVDDEEKQHFIPFQQIAMETYIRQR 360
Query: 361 QLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNFSHL 420
QLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNFSHL
Sbjct: 361 QLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNFSHL 420
Query: 421 VDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEGKLL 480
VDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEGKLL
Sbjct: 421 VDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEGKLL 480
Query: 481 EKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQETR 540
EKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQETR
Sbjct: 481 EKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQETR 540
Query: 541 DKSERAFGVAFVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKEL 600
DKSERAFGVAFVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKEL
Sbjct: 541 DKSERAFGVAFVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKEL 600
Query: 601 QASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKLMEV 660
QASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKLMEV
Sbjct: 601 QASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKLMEV 660
Query: 661 DGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYI 720
DGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYI
Sbjct: 661 DGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYI 720
Query: 721 YKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRFYGQ 780
YKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRFYGQ
Sbjct: 721 YKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRFYGQ 780
Query: 781 SKDGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYLPSIINDVKLVFDPVELSVLF 840
SKDGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYLPSIINDVKLVFDPVELSVLF
Sbjct: 781 SKDGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYLPSIINDVKLVFDPVELSVLF 840
Query: 841 CKFIQSIPDNQLVRQKLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQLDDNSNKPDHE 900
CKFIQSIPDNQLVRQKLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQLDDNSNKPDHE
Sbjct: 841 CKFIQSIPDNQLVRQKLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQLDDNSNKPDHE 900
Query: 901 ASSQLLSNILEVLDRKDVGATAVHIQLIMERLLRRINRTVIGMNRQSPHIGSFVACMIAL 960
ASSQLLSNILEVLDRKDVGATAVHIQLIMERLLRRINRTVIGMNRQSPHIGSFVACMIAL
Sbjct: 901 ASSQLLSNILEVLDRKDVGATAVHIQLIMERLLRRINRTVIGMNRQSPHIGSFVACMIAL 960
Query: 961 LQQMDDSHYSHYISTFKTRQDIIDFLMETFIMFKDLIGKNVYAKDWMVMNMTQNRVFLRA 1020
LQQMDDSHYSHYISTFKTRQDIIDFLMETFIMFKDLIGKNVYAKDWMVMNMTQNRVFLRA
Sbjct: 961 LQQMDDSHYSHYISTFKTRQDIIDFLMETFIMFKDLIGKNVYAKDWMVMNMTQNRVFLRA 1020
Query: 1021 INQFAEVLTRFFMDQASFELQLWNNYFHLAVAFLTHESLQLETFSQAKRNKIVKKYGDMR 1080
INQFAEVLTRFFMDQASFELQLWNNYFHLAVAFLTHESLQLETFSQAKRNKIVKKYGDMR
Sbjct: 1021 INQFAEVLTRFFMDQASFELQLWNNYFHLAVAFLTHESLQLETFSQAKRNKIVKKYGDMR 1080
Query: 1081 KEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVTLTPEVELRKATIPIFFDMMQCEFNFSG 1140
KEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVTLTPEVELRKATIPIFFDMMQCEFNFSG
Sbjct: 1081 KEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVTLTPEVELRKATIPIFFDMMQCEFNFSG 1140
Query: 1141 NGNFHMFENELITKLDQEVEGGRGDEQYKVLLEKLLLEHCRKHKYLSSSGEVFALLVSSL 1200
NGNFHMFENELITKLDQEVEGGRGDEQYKVLLEKLLLEHCRKHKYLSSSGEVFALLVSSL
Sbjct: 1141 NGNFHMFENELITKLDQEVEGGRGDEQYKVLLEKLLLEHCRKHKYLSSSGEVFALLVSSL 1200
Query: 1201 LENLLDYRTIIMQDESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLRDLHRDCENYTEA 1260
LENLLDYRTIIMQDESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLRDLHRDCENYTEA
Sbjct: 1201 LENLLDYRTIIMQDESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLRDLHRDCENYTEA 1260
Query: 1261 AYTLLLHAELLQWSDKPCVPHLLQKDSYYVYTQQELKEKLYQEIISYFDKGKMWEKAIKL 1320
AYTLLLHAELLQWSDKPCVPHLLQKDSYYVYTQQELKEKLYQEIISYFDKGKMWEKAIKL
Sbjct: 1261 AYTLLLHAELLQWSDKPCVPHLLQKDSYYVYTQQELKEKLYQEIISYFDKGKMWEKAIKL 1320
Query: 1321 SKELAETYESKVFDYEGLGNLLKKRASFYENIIKAMRPQPEYFAVGYYGQGFPSFLRNKI 1380
SKELAETYESKVFDYEGLGNLLKKRASFYENIIKAMRPQPEYFAVGYYGQGFPSFLRNKI
Sbjct: 1321 SKELAETYESKVFDYEGLGNLLKKRASFYENIIKAMRPQPEYFAVGYYGQGFPSFLRNKI 1380
Query: 1381 FIYRGKEYERREDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPS 1440
FIYRGKEYERREDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPS
Sbjct: 1381 FIYRGKEYERREDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPS 1440
Query: 1441 YKDKPVPEQILNYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILK 1500
YKDKPVPEQILNYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILK
Sbjct: 1441 YKDKPVPEQILNYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILK 1500
Query: 1501 WFEVKQISTEEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVM 1560
WFEVKQISTEEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVM
Sbjct: 1501 WFEVKQISTEEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVM 1560
Query: 1561 GGFSNYEKAFFTEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHE 1620
GGFSNYEKAFFTEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHE
Sbjct: 1561 GGFSNYEKAFFTEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHE 1620
Query: 1621 RLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSIVLPYIMSSTLRRLSITSVTSSVV 1680
RLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSIVLPYIMSSTLRRLSITSVTSSVV
Sbjct: 1621 RLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSIVLPYIMSSTLRRLSITSVTSSVV 1680
Query: 1681 STSSNSSDNAPSRPGSDGSILEPLLERRASSGARVEDLSLREENSENRISKFKRKDWSLS 1740
STSSNSSDNAPSRPGSDGSILEPLLERRASSGARVEDLSLREENSENRISKFKRKDWSLS
Sbjct: 1681 STSSNSSDNAPSRPGSDGSILEPLLERRASSGARVEDLSLREENSENRISKFKRKDWSLS 1740
Query: 1741 KSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRT 1800
KSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRT
Sbjct: 1741 KSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRT 1800
Query: 1801 LSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKS 1860
LSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKS
Sbjct: 1801 LSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKS 1860
Query: 1861 GIPTSEPGSQ 1870
GIPTSEPGSQ
Sbjct: 1861 GIPTSEPGSQ 1870
>gi|4503355 dedicator of cytokinesis 1 [Homo sapiens]
Length = 1865
Score = 2366 bits (6131), Expect = 0.0
Identities = 1213/1912 (63%), Positives = 1475/1912 (77%), Gaps = 111/1912 (5%)
Query: 1 MARWIPTKRQ-KYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIF 59
M RW+PTKR+ KYGVA YNY+A ELSLQIGDTVHILE YEGWYRGYTL+ KSKKGIF
Sbjct: 1 MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIF 60
Query: 60 PETYIHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQ 119
P +YIHLKEA VE GQHETVIPG+LPL+QE+T+TLREW+ IWR+LYV + +FR ++
Sbjct: 61 PASYIHLKEAIVEGKGQHETVIPGDLPLIQEVTTTLREWSTIWRQLYVQDNREMFRSVRH 120
Query: 120 MTYSLIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETS 179
M Y LIEWRSQILSGTLP+DEL ELKKKVTAKID+GNR+L LDLVVRD++GNILDP+ TS
Sbjct: 121 MIYDLIEWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTS 180
Query: 180 TIALFKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVCNIGEDA 239
TI+LF+AHE+ASK++EE++QEEKS QN+D+ Q+ F+ + L+VN KN VC IGEDA
Sbjct: 181 TISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKFAATPSLALFVNLKNVVCKIGEDA 240
Query: 240 ELFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQ 299
E+ M+LYDP +S FISENYL+RW S+G+PK+I++L+NL+AVFTDL S DL R ++S VCQ
Sbjct: 241 EVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKREKISFVCQ 300
Query: 300 IVRVGHMELKEG--KKHTCGLRRPFGVAVMDITDIIHGKVDDEEKQHFIPFQQIAMETYI 357
IVRVG MEL++ +K T GLRRPFGVAVMD+TDII+GKVDDE+KQHFIPFQ +A
Sbjct: 301 IVRVGRMELRDNNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPVA----- 355
Query: 358 RQRQLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNF 417
GEN+ L +V+NKVIAAKEVNHKGQGLWV+LKLLPGD+ Q++K F
Sbjct: 356 ----------------GENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEF 399
Query: 418 SHLVDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEG 477
HLVDR+TA+ARK GFPEII+PGDVRNDIYVTL+ G+FDKG K T KNVEVT+SV+DE+G
Sbjct: 400 PHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVYDEDG 459
Query: 478 KLLEKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQ 537
K LE I PGAG E ISEYKSV+YYQVKQP W+ETVKV+I IE+V R H+RFTFRHRSSQ
Sbjct: 460 KRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQ 519
Query: 538 ETRDKSERAFGVAFVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEE 597
+++DKSE+ F +AFVKLM DGTTL+DG HDL+VYK + KK+EDA YL+LP TK E+EE
Sbjct: 520 DSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDAATYLSLPSTKAELEE 579
Query: 598 KELQASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKL 657
K A+ + S +KDSFQI+TL+CSTKLTQNVDLLGLL WRSN+ ++ NL++L
Sbjct: 580 KGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQNVDLLGLLKWRSNTSLLQQNLRQL 639
Query: 658 MEVDGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLE 717
M+VDGGE+VKFLQDTLDALFNIMME S+SET+D LVFDALVFII LI D KFQHFNPVLE
Sbjct: 640 MKVDGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLE 699
Query: 718 TYIYKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRF 777
TYI KHFSATLAY KL+KVL YV A+ E L+ A+KAL+ +F+FI++SR+L+ +
Sbjct: 700 TYIKKHFSATLAYTKLTKVLKNYVDGAEKPGVNEQLYKAMKALESIFKFIVRSRILFNQL 759
Query: 778 YGQSKDGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYLPSIINDVKLVFDPVELS 837
Y ++K +F S+ QLF + N +M ++ V++KGAALKYLP+I+NDVKLVFDP ELS
Sbjct: 760 Y-ENKGEADFVESLLQLFRSINDMMSSMSDQTVRVKGAALKYLPTIVNDVKLVFDPKELS 818
Query: 838 VLFCKFIQSIPDNQLVRQKLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQLDDNSNKP 897
+F +FI ++P L QKL C+ +IV S LF Q +CRE+LLP++TDQL L+ +
Sbjct: 819 KMFTEFILNVPMGLLTIQKLYCLIEIVHSDLFTQHDCREILLPMMTDQLKYHLE---RQE 875
Query: 898 DHEASSQLLSNILEVLDRKDVGATAVHIQLIMERLLRRINRTVIGMNRQSPHIGSFVACM 957
D EA QLLS+ILEVL RKDVG T H+Q+IME+LLR +NRTVI M R S IG+FVACM
Sbjct: 876 DLEACCQLLSHILEVLYRKDVGPTQRHVQIIMEKLLRTVNRTVISMGRDSELIGNFVACM 935
Query: 958 IALLQQMDDSHYSHYISTF-KTRQDIIDFLMETFIMFKDLIGKNVYAKDWMVMNMTQNRV 1016
A+L+QM+D HY+H I TF K R D++DFLMETFIMFK+LIGKNVY DW++MNM QN+V
Sbjct: 936 TAILRQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKV 995
Query: 1017 FLRAINQFAEVLTRFFMDQASFELQLWNNYFHLAVAFLTHESLQLETFSQAKRNKIVKKY 1076
FLRAINQ+A++L + F+DQA+FELQLWNNYFHLAVAFLT ESLQLE FS AKR KI+ KY
Sbjct: 996 FLRAINQYADMLNKKFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRAKILNKY 1055
Query: 1077 GDMRKEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVTLTPEVELRKATIPIFFDMMQCEF 1136
GDMR++IGF IRDMWYNLG HKIKFIP MVGPILE+TL PE ELRKATIPIFFDMMQCEF
Sbjct: 1056 GDMRRQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEF 1115
Query: 1137 NFSGNGNFHMFENELITKLDQEVEGGRGDEQYKVLLEKLLLEHCRKHKYLSSSGEVFALL 1196
+ +F MFENE+ITKLD EVEGGRGDEQYKVL +K+LLEHCRKHKYL+ +GE F L
Sbjct: 1116 H--STRSFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVKL 1173
Query: 1197 VSSLLENLLDYRTIIMQDESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLRDLHRDCEN 1256
V L+E LLDYRT IM DE+KENRMSCTVNVLNFYKE +RE++YIRYLYKL DLH++C+N
Sbjct: 1174 VVRLMERLLDYRT-IMHDENKENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDN 1232
Query: 1257 YTEAAYTLLLHAELLQWSDKPCVPHLLQKDSYYVYTQQELKEKLYQEIISYFDKGKMWEK 1316
YTEAAYTLLLHA+LL+WS+ CV HL Q+D Y TQ +LKE+LYQEII YFDKGKMWE+
Sbjct: 1233 YTEAAYTLLLHAKLLKWSEDVCVAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEE 1292
Query: 1317 AIKLSKELAETYESKVFDYEGLGNLLKKRASFYENIIKAMRPQPEYFAVGYYGQGFPSFL 1376
AI L KELAE YE+++FDYE L LLKK+A FYENI+K +RP+P+YFAVGYYGQGFP+FL
Sbjct: 1293 AIALGKELAEQYENEMFDYEQLSELLKKQAQFYENIVKVIRPKPDYFAVGYYGQGFPTFL 1352
Query: 1377 RNKIFIYRGKEYERREDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMS 1436
R K+FIYRGKEYERREDF RLLTQFPNAEKM +T+PPG+DIK+SP QY+QCFTVKP +
Sbjct: 1353 RGKVFIYRGKEYERREDFEARLLTQFPNAEKMKTTSPPGDDIKNSPGQYIQCFTVKPKLD 1412
Query: 1437 LPPSYKDKPVPEQILNYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFP 1496
LPP + +PV EQI+++YR NEVQ+F YSRP RKGEK+PDNEFA MWIERT YTTAY P
Sbjct: 1413 LPPKF-HRPVSEQIVSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWIERTIYTTAYKLP 1471
Query: 1497 GILKWFEVKQISTEEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVD 1556
GIL+WFEVK + EISPLENAIETM+LTN++I++ VQQH D SL ++PLSMLL+GIVD
Sbjct: 1472 GILRWFEVKSVFMVEISPLENAIETMQLTNDKINSMVQQHLDDPSLPINPLSMLLNGIVD 1531
Query: 1557 PAVMGGFSNYEKAFFTEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLK 1616
PAVMGGF+NYEKAFFT++YLQEHPE EK+E LK LIA Q+P L EGIRIHG+K+TE L+
Sbjct: 1532 PAVMGGFANYEKAFFTDRYLQEHPEAHEKIEKLKDLIAWQIPFLAEGIRIHGDKVTEALR 1591
Query: 1617 PLHERLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSIVLPYIMSSTLRRLSITSVT 1676
P HER+ +CF++LKEKVEK YGV +P +L +R+ SR S+V + M S+ R LS+ SV
Sbjct: 1592 PFHERMEACFKQLKEKVEKEYGVRIMPSSLDDRRGSRPRSMVRSFTMPSSSRPLSVASV- 1650
Query: 1677 SSVVSTSSNSSDNAPSRPGSDGSILEPLLERRASSGARVEDLSLREENSENRISKFKRKD 1736
SS SSD+ PSRPGSDG LEPLL ++ S R +D L +++ E K K+K+
Sbjct: 1651 ------SSLSSDSTPSRPGSDGFALEPLLPKKMHS--RSQD-KLDKDDLEKE-KKDKKKE 1700
Query: 1737 WSLSKSQVIAEKAPEP--------------DLMSPTRKAQRPKSLQLMD----NRLSPFH 1778
SK Q I EK +P + +SP R QRPKS Q+M+ R
Sbjct: 1701 KRNSKHQEIFEKEFKPTDISLQQSEAVILSETISPLR-PQRPKS-QVMNVIGSERRFSVS 1758
Query: 1779 GSSPPQSTPLSPPPLTPKATRTLSSPS-------------------------------LQ 1807
SSP S+ +PPP+TP+A + S S ++
Sbjct: 1759 PSSP--SSQQTPPPVTPRAKLSFSMQSSLELNGMTGADVADVPPPLPLKGSVADYGNLME 1816
Query: 1808 TDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARK 1859
+ +P PPPPPP + L PPLP +K PPPPPPK +
Sbjct: 1817 NQDLLGSPTPPPPPPHQR----------HLPPPLP----SKTPPPPPPKTTR 1854
>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
Length = 1830
Score = 1940 bits (5025), Expect = 0.0
Identities = 1009/1818 (55%), Positives = 1302/1818 (71%), Gaps = 54/1818 (2%)
Query: 1 MARWIPTKRQKYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIFP 60
MA W ++++GVAIYN+ S +LSLQIGD V I E WYRGY +++K +GIFP
Sbjct: 1 MAPWRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFP 60
Query: 61 ETYIHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQM 120
+++IH+KE TVE E +IP E+PL QE+T+TL EW IW++LYV +K F Q+Q M
Sbjct: 61 KSFIHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSM 120
Query: 121 TYSLIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETST 180
Y L+EWRSQ+LSGTLPKDEL ELK+KVT+KID+GN++L LDL+VRD++GNILDPD TS
Sbjct: 121 MYDLMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSV 180
Query: 181 IALFKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVCNIGEDAE 240
I+LF AHE A+ +I E+I+EE S Q D S S+ T+ LYV +NFVC IGEDAE
Sbjct: 181 ISLFHAHEEATDKITERIKEEMSKDQP-DYAMYSRISSSPTHSLYVFVRNFVCRIGEDAE 239
Query: 241 LFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQI 300
LFM+LYDP++ T ISENYL+RWGS G PKEIE LNNL+ VFTDL + DL R ++ L+CQI
Sbjct: 240 LFMSLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQI 299
Query: 301 VRVGHMELKE--GKKHTCGLRRPFGVAVMDITDIIHGKVD-DEEKQHFIPFQQIAMETYI 357
VRVG M+LK+ KK T GLRRPFGVAVMDITDII GK + DEEKQHFIPF +
Sbjct: 300 VRVGKMDLKDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVT----- 354
Query: 358 RQRQLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNF 417
EN+ L S+L KVIA+K + GQGLWV++K+L GD+ Q++K++
Sbjct: 355 ----------------AENDFLHSLLGKVIASKG-DSGGQGLWVTMKMLVGDIIQIRKDY 397
Query: 418 SHLVDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEG 477
HLVDR+T +ARK+GFPEII+PGDVRNDIY+TL+ G+FDK K T +NVEV M V E+G
Sbjct: 398 PHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDG 457
Query: 478 KLLEKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQ 537
K L AI GAG + ++EY+SVVYYQVKQP W ETVKV++ IE++ R H+RF FRHRSS
Sbjct: 458 KTLPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSL 517
Query: 538 ETRDKSERAFGVAFVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEE 597
E++DK E+ F +++VKLM DGTTL DG HDLVV KGD+KKMEDA YLTLP + +E
Sbjct: 518 ESKDKGEKNFAMSYVKLMKEDGTTLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVEN 577
Query: 598 KELQASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKL 657
K S++ + S++D F I+TL+CSTKLTQNV LLGLL WR Q ++ NL+KL
Sbjct: 578 KGATLSRSSSSVGGLSVSSRDVFSISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKL 637
Query: 658 MEVDGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLE 717
VDG E+VKFLQDTLDALFNIMME S S+ YD LVFDAL++II LI D KFQHFN VLE
Sbjct: 638 KIVDGEEVVKFLQDTLDALFNIMMEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLE 697
Query: 718 TYIYKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRF 777
YI +HFSATLAY KL VL Y+ + + E + LKAL+Y+F+FI++SR L+ +
Sbjct: 698 AYIQQHFSATLAYKKLMTVLKTYLDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQL 757
Query: 778 YGQSKDGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYLPSIINDVKLVFDPVELS 837
Y + K+ EF S+R+LF + N LM + + ++ AALKY+PS+++DV++VFD LS
Sbjct: 758 Y-EGKEQMEFEESMRRLFESINNLMKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLS 816
Query: 838 VLFCKFIQSIPDNQLVRQKLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQLDDNSNKP 897
L +F IP +L +QK+ M +IV+S LF++ ECR++LLP++T +L L+ +
Sbjct: 817 QLLYEFYTCIPPVKLQKQKVQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQ 876
Query: 898 ----DHEASSQLLSNILEVLDRKDVGATAVHIQLIMERLLRRINRTVIGMNRQSPHIGSF 953
+ + +LL++ILEVL +D T HIQ IM +LLR +NRTVI M R I F
Sbjct: 877 HQVLERKYCVELLNSILEVLSYQDAAFTYHHIQEIMVQLLRTVNRTVITMGRDHILISHF 936
Query: 954 VACMIALLQQMDDSHYSHYISTFKTRQDIIDFLMETFIMFKDLIGKNVYAKDWMVMNMTQ 1013
VACM A+L QM D HYS YI TF+T +++DFLMETFIMFKDLIGKNVY DWM M+M Q
Sbjct: 937 VACMTAILNQMGDQHYSFYIETFQTSSELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQ 996
Query: 1014 NRVFLRAINQFAEVLTRFFMDQASFELQLWNNYFHLAVAFLTHESLQLETFSQAKRNKIV 1073
NRVFLRAIN+FAE + + F++ +FE QLWNNYFHLAVAF+T +SLQLE FS AK NKI+
Sbjct: 997 NRVFLRAINKFAETMNQKFLEHTNFEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKIL 1056
Query: 1074 KKYGDMRKEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVTLTPEVELRKATIPIFFDMMQ 1133
KYGDMR+ IGF IRDMWY LG +KI FIP MVGPILE+TL PE ELRKATIPIFFDMM
Sbjct: 1057 NKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEMTLIPEAELRKATIPIFFDMML 1116
Query: 1134 CEFNFSGNGNFHMFENELITKLDQEVEGGRGDEQYKVLLEKLLLEHCRKHKYLSSSGEVF 1193
CE+ SG+ F FENE+I KLD EVEGGRGDEQY LLE +L+E +H ++ S E F
Sbjct: 1117 CEYQRSGD--FKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENF 1174
Query: 1194 ALLVSSLLENLLDYRTIIMQDESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLRDLHRD 1253
LV LLE LLDYR + M DESK+NRMSCTVN+LNFYK+ RE++YIRYLYKLRDLH D
Sbjct: 1175 VNLVKGLLEKLLDYRGV-MTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLD 1233
Query: 1254 CENYTEAAYTLLLHAELLQWSDKPCVPHLLQKDSYYVYTQQELKEKLYQEIISYFDKGKM 1313
C+NYTEAAYTLLLH LL+WSD+ C ++Q + T ++LKE LY+ II YFDKGKM
Sbjct: 1234 CDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQLKETLYETIIGYFDKGKM 1293
Query: 1314 WEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFYENIIKAMRPQPEYFAVGYYGQGFP 1373
WE+AI L KELAE YE ++FDYE L L ++A FYE+I+K +RP+P+YFAVGYYGQGFP
Sbjct: 1294 WEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFP 1353
Query: 1374 SFLRNKIFIYRGKEYERREDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKP 1433
SFLRNK+FIYRGKEYERREDF ++L+TQFPNAEKM +T+ PG+D+K++P QY+QCFTV+P
Sbjct: 1354 SFLRNKVFIYRGKEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQP 1413
Query: 1434 VMSLPPSYKDKPVPEQILNYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAY 1493
V+ P +K+KPVP+QI+N+Y++N VQ+F YSRP R+G DP+NEFA+MWIERT++ TAY
Sbjct: 1414 VLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDPENEFASMWIERTSFVTAY 1473
Query: 1494 TFPGILKWFEVKQISTEEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSG 1553
PGIL+WFEV +S ISPLENAIETM NE+I + Q+ D +L ++PLSMLL+G
Sbjct: 1474 KLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNG 1533
Query: 1554 IVDPAVMGGFSNYEKAFFTEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTE 1613
IVDPAVMGGF+ YEKAFFTE+Y+++HPEDQ+K+ LK LIA Q+P L GI+IH +++++
Sbjct: 1534 IVDPAVMGGFAKYEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSD 1593
Query: 1614 QLKPLHERLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSIVLPYIMSSTLRRLSIT 1673
L+P H+R+ CF+ LK KVEK YGV + P+ +R+ R S++ Y R++SI
Sbjct: 1594 NLRPFHDRMEECFKNLKMKVEKEYGVREM-PDFDDRRVGRPRSMLRSY------RQMSII 1646
Query: 1674 SVTSSVVSTSSNSSDNAPSRPGSDGSILEPLLERRASSGARVEDLSLREENSENRISKFK 1733
S+ S NS + PS+P S+ LE L + + E +S E ++ + K
Sbjct: 1647 SL------ASMNSDCSTPSKPTSESFDLE-LASPKTPRVEQEEPISPGSTLPEVKLRRSK 1699
Query: 1734 RKDWSLSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPL 1793
++ S + A E DL +RK + + D LS H + P +++ LS
Sbjct: 1700 KRTKRSSVVFADEKAAAESDLKRLSRKHE-----FMSDTNLSE-HAAIPLKASVLSQMSF 1753
Query: 1794 TPKATRTLSSPSLQTDGI 1811
++ T+ + +L GI
Sbjct: 1754 ASQSMPTIPALALSVAGI 1771
>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
Length = 1966
Score = 1152 bits (2979), Expect = 0.0
Identities = 687/1924 (35%), Positives = 1076/1924 (55%), Gaps = 144/1924 (7%)
Query: 4 WIPTKRQKYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIFPETY 63
WIPT+ +KYGV I ++ + LSL+IGDTV ILE +GWYRG+ L+N + KGIFP +Y
Sbjct: 2 WIPTEHEKYGVVIASFRGTVPYGLSLEIGDTVQILEKCDGWYRGFALKNPNIKGIFPSSY 61
Query: 64 IHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQMTYS 123
+HLK A V++ GQ E VIP E ++ E+TSTLR+W +W++LYV N+ LF +L +
Sbjct: 62 VHLKNACVKNKGQFEMVIPTEDSVITEMTSTLRDWGTMWKQLYVRNEGDLFHRLWHIMNE 121
Query: 124 LIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETSTIAL 183
+++ R Q+L G L D + ++K+ +TA++D GN LGLDLV R + ++DP++ S L
Sbjct: 122 ILDLRRQVLVGHLTHDRMKDVKRHITARLDWGNEQLGLDLVPRKEYA-MVDPEDISITEL 180
Query: 184 FKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVC-NIGEDAELF 242
++ E ++ + +Q ++ L+V K+ +C N+GE+ E+
Sbjct: 181 YRLMEHRHRKKDTPVQAS-------------------SHHLFVQMKSLMCSNLGEELEVI 221
Query: 243 MALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQIVR 302
+L+D ++ ISE + +R NG+PK +K ++F DL S +L R + + I+R
Sbjct: 222 FSLFDSKENRPISERFFLRLNRNGLPKAPDKPERHCSLFVDLGSSEL-RKDIYITVHIIR 280
Query: 303 VGHMELKEGKKHTCGL--RRPFGVAVMDITDIIHGKVDDEEKQHFIPFQQIAMETYIRQR 360
+G M E KK+ C + RRPFG AV+ I D++ G+ D+ + ++ Y+
Sbjct: 281 IGRMGAGE-KKNACSVQYRRPFGCAVLSIADLLTGETKDD----------LILKVYMCNT 329
Query: 361 QLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNFSHL 420
+ + I EN ++ K+ A + GL VSL+LL GD+ Q+++ +S +
Sbjct: 330 ESEW------YQIHEN-----IIKKLNARYNLTGSNAGLAVSLQLLHGDIEQIRREYSSV 378
Query: 421 VDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEGKLL 480
+I RK+GF II+PG++RND+Y+T+ GEF+KG K +NVEVTM + D G+ L
Sbjct: 379 FSHGVSITRKLGFSNIIMPGEMRNDLYITIERGEFEKGGKSVARNVEVTMFIVDSSGQTL 438
Query: 481 EKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQETR 540
+ I G+G SEY S V Y P W E +K+ I +++ HIRF FRH S++E
Sbjct: 439 KDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPVDKFRGAHIRFEFRHCSTKEKG 498
Query: 541 DKSERAFGVAFVKLMNPDGTTLQDGRHDLVVYK-GDNKKMEDAKFYLTLPGTKMEMEEKE 599
+K + FG +FV LM DG TL DG H+L+V+K +N ++D YL LP +K
Sbjct: 499 EK--KLFGFSFVPLMQEDGRTLPDGTHELIVHKCEENTNLQDTTRYLKLPFSKGIFLGNN 556
Query: 600 LQASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKLME 659
QA K +TK+SF I + +CSTKLTQN D+L LL WR++ I L KL E
Sbjct: 557 NQAMK----------ATKESFCITSFLCSTKLTQNGDMLDLLKWRTHPDKITGCLSKLKE 606
Query: 660 VDGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETY 719
+DG EIVKFLQDTLD LF I+ E +S+ Y VFD+LV II+L+ D KF HF PV++TY
Sbjct: 607 IDGSEIVKFLQDTLDTLFGILDE--NSQKYGSKVFDSLVHIINLLQDSKFHHFKPVMDTY 664
Query: 720 IYKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRFYG 779
I HF+ LAY L KVL +YV ++ + E + LKA +Y+F++I+QSR L+ G
Sbjct: 665 IESHFAGALAYRDLIKVLKWYVDRITEAERQEHIQEVLKAQEYIFKYIVQSRRLFSLATG 724
Query: 780 QSKDGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYL---PSIINDVKLVFDPVEL 836
+ +EF I++L ++ + + + + + + +L P++ +++ +FD E+
Sbjct: 725 GQNE-EEFRCCIQELLMSVRFFLSQESKGSGALSQSQAVFLSSFPAVYSELLKLFDVREV 783
Query: 837 SVLFCKFIQSIP-----DNQLVRQKLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQLD 891
+ L + S+P D+ L KL C+ K VES L+ + R +LLP++ L L
Sbjct: 784 ANLVQDTLGSLPTILHVDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHIHLQ 843
Query: 892 DNSNKPDHEASSQLLSNILEVLDRKDVGATAVH-IQLIMERLLRRINRTVIGM-NRQSPH 949
+ D +++LSN+ ++ + + + I +I+ LL + RT++ + +R P
Sbjct: 844 EQK---DLIMCARILSNVFCLIKKNSSEKSVLEEIDVIVASLLDILLRTILEITSRPQPS 900
Query: 950 -----------IGSFVACMIALLQQMDDSHYSHYISTFKTRQDIIDFLMETFIMFKDLIG 998
G FVAC+++LL+QM D HY + +F T++++ DFL++ F +F+ LI
Sbjct: 901 SSAMRFQFQDVTGEFVACLLSLLRQMTDRHYQQLLDSFNTKEELRDFLLQIFTVFRILIR 960
Query: 999 KNVYAKDWMVMNMTQNRVFLRAINQFAEVLTRFFMDQASFELQLWNNYFHLAVAFLTHES 1058
++ KDW VM + N V + + ++ L + F+++ +F+ ++W++YF+LAV F+
Sbjct: 961 PEMFPKDWTVMRLVANNVIITTVLYLSDALRKNFLNE-NFDYKIWDSYFYLAVIFINQLC 1019
Query: 1059 LQLETFSQAKRNKIVKKYGDMRKEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVTLTPEV 1118
LQLE F+ +K+ K+++KYGDMR +G I MW NLG HK+ FIP+++GP LEVTL P+
Sbjct: 1020 LQLEMFTPSKKKKVLEKYGDMRVTMGCEIFSMWQNLGEHKLHFIPALIGPFLEVTLIPQP 1079
Query: 1119 ELRKATIPIFFDMMQCEFNFSGNGNFHMFENELITKLDQEVEGGRGDEQYKVLLEKLLLE 1178
+LR IPIF DMM E SGN F E +LI KLD + G+GDE Y+ L +LL+
Sbjct: 1080 DLRNVMIPIFHDMMDWEQRRSGN--FKQVEAKLIDKLDSLMSEGKGDETYRELFNSILLK 1137
Query: 1179 HCRKHKYLSSSGEVFALLVSSLLENLLDYRTIIMQDESKENRMSCTVNVLNFYK-EKKRE 1237
+ + S + A V+ L+E LLDYR + E ++ CTV++LNFYK E +E
Sbjct: 1138 KIERETWRESGVSLIAT-VTRLMERLLDYRDCMKMGEVDGKKIGCTVSLLNFYKTELNKE 1196
Query: 1238 DIYIRYLYKLRDLHRDCENYTEAAYTLLLHAELLQWSDKPCVPHLLQKDSYYVYTQQELK 1297
++YIRY++KL DLH +N+TEAAYTLLL+ ELL+WSD+P L +Y + T+ + K
Sbjct: 1197 EMYIRYIHKLYDLHLKAQNFTEAAYTLLLYDELLEWSDRPLREFL----TYPMQTEWQRK 1252
Query: 1298 EKLYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFYENIIKAMR 1357
E L+ II FD+GK WE I L +++AE YES +DY L + AS Y+ I+ R
Sbjct: 1253 EHLHLTIIQNFDRGKCWENGIILCRKIAEQYES-YYDYRNLSKMRMMEASLYDKIMDQQR 1311
Query: 1358 PQPEYFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSLRLLTQFPNAEKMTSTTPPGED 1417
+PE+F VG+YG+ FP FLRNK F+ RG +YER E F R+L +FP+A M P E
Sbjct: 1312 LEPEFFRVGFYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPDET 1371
Query: 1418 IKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQILNYYRANEVQQFRYSRPFRKGEKDPDN 1477
I + QY+Q + V P+ + + VP+ I ++Y+ N + +FRY RPF KG KD +N
Sbjct: 1372 IFQAEAQYLQIYAVTPIPESQEVLQREGVPDNIKSFYKVNHIWKFRYDRPFHKGTKDKEN 1431
Query: 1478 EFATMWIERTTYTTAYTFPGILKWFEVKQISTEEISPLENAIETMELTNERISNCVQQHA 1537
EF ++W+ERT+ + PGI +WFEV++ E+SPLENAIE +E N+++ + Q
Sbjct: 1432 EFKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQ 1491
Query: 1538 WDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFFTEKYLQEHPEDQEKVELLKRLIALQM 1597
+ +++PL+M L+G++D AV GG S Y++AFF ++Y+ HPED EK+ L+ L+ Q
Sbjct: 1492 TRQMQNINPLTMCLNGVIDAAVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQA 1551
Query: 1598 PLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEK--VEKHYGVITLPP----------- 1644
+L G+ +H + + + ++PLH++L F +K +++ + P
Sbjct: 1552 QILEFGLAVHEKFVPQDMRPLHKKLVDQFFVMKSSLGIQEFSACMQASPVHFPNGSPRVC 1611
Query: 1645 -NLTERKQSRTGSIVLPY---IMSSTLRRLSITSVTSSVVSTSSNSSDNAPS-------R 1693
N S G+ V+P + + R S +S++S + SN + + S +
Sbjct: 1612 RNSAPASVSPDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITGQSESSDEVFNMQ 1671
Query: 1694 PGSDGSIL------EPLLERRASSGARVEDLSLREENSENRISKFKRKDWSLSKSQVIAE 1747
P S L P + A S AR L L +++ K R++ LS E
Sbjct: 1672 PSPSTSSLSSTHSASPNVTSSAPSSARASPL-LSDKH------KHSRENSCLSP----RE 1720
Query: 1748 KAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQ 1807
+ +P +QR + D L S P S P TP + S +
Sbjct: 1721 RPCSAIYPTPVEPSQRMLFNHIGDGALP---RSDPNLSAPEKAVNPTPSSWSLDSGKEAK 1777
Query: 1808 TDGIAATPVPPPPPPKSKPYEGSQRNSTELAPP----LPVRREAKAPPPPPPKARKSGIP 1863
+ + PP PP+ R++T ++P P++ ++ P P + G+
Sbjct: 1778 NMSDSGKLISPPVPPRPTQTASPARHTTSVSPSPAGRSPLKGSVQSFTPSPVEYHSPGLI 1837
Query: 1864 TSEP 1867
++ P
Sbjct: 1838 SNSP 1841
>gi|31415870 dedicator of cytokinesis 3 [Homo sapiens]
Length = 2030
Score = 1144 bits (2958), Expect = 0.0
Identities = 678/1816 (37%), Positives = 1048/1816 (57%), Gaps = 100/1816 (5%)
Query: 4 WIPTKRQKYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIFPETY 63
W PT+ +KYGV I ++ S L L+IG+TV ILE EGWYRG + + + KGIFP Y
Sbjct: 2 WTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPANY 61
Query: 64 IHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQMTYS 123
IHLK+A V + GQ+ETV+P E +V E+T+TL+EWA +W++LYV +K+ LF +L+ +
Sbjct: 62 IHLKKAIVSNRGQYETVVPLEDSIVTEVTATLQEWASLWKQLYVKHKVDLFYKLRHVMNE 121
Query: 124 LIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETSTIAL 183
LI+ R Q+LSG L +D++ E+K+ +T ++D GN LGLDLV R D ++D D+ S L
Sbjct: 122 LIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDF-EVVDSDQISVSDL 180
Query: 184 FKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVCN-IGEDAELF 242
+K H S R + +Q+ S + + R + +++ K+F N IGED ++F
Sbjct: 181 YKMH--LSSR--QSVQQSTSQVDTMRPRHGETCRMPVPHHFFLSLKSFTYNTIGEDTDVF 236
Query: 243 MALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQIVR 302
+LYD + ISE +L+R NG P+ EK+ + A+FTDLSS D+ R + +V ++R
Sbjct: 237 FSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRD-LYIVAHVIR 295
Query: 303 VGHMELKEGKKHTCGL--RRPFGVAVMDITDIIHGKVDDEEKQHFIPFQQIAMETYIRQR 360
+G M L + KK L RRP+G AV+ I D++ + +E++ F+ ++ Y
Sbjct: 296 IGRMLLNDSKKGPPHLHYRRPYGCAVLSILDVLQSLTEVKEEKDFV------LKVYTCNN 349
Query: 361 QLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNFSHL 420
+ S I EN ++ K A GL +SL+LL GD+ Q+++ +
Sbjct: 350 ESEWSQ------IHEN-----IIRKSSAKYSAPSASHGLIISLQLLRGDMEQIRRENPMI 398
Query: 421 VDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEGKLL 480
+R AI RK+GFP++I+PGD+RND+Y+TL G+F++G K KN+EVTM V +G++L
Sbjct: 399 FNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEIL 458
Query: 481 EKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQETR 540
+ I G+G S Y S V Y P W E +K+ I I+ H+RF FRH S T+
Sbjct: 459 KDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCS---TK 515
Query: 541 DKSERA-FGVAFVKLMNPDGTTLQDGRHDLVVYKGD-NKKMEDAKFYLTLPGTKMEMEEK 598
DK E+ FG AF LM DGTTL D H+L VYK D N + YL LP K +
Sbjct: 516 DKGEKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCK-----E 570
Query: 599 ELQASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKLM 658
+ N+ + + STK+SF I+T + STKLTQNVDLL LL W++ I L +L
Sbjct: 571 DYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDVLGRLR 630
Query: 659 EVDGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLET 718
V G EIVKFLQD LD LF I+ + ++E Y LVF +LVFII+L+ DIK+ HF PV++T
Sbjct: 631 HVSGEEIVKFLQDILDTLFVILDD--NTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDT 688
Query: 719 YIYKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRFY 778
YI KHF+ LAY +L + L +Y+ + + + + + A++AL+YLF+FI+QSR+LY R
Sbjct: 689 YIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRAT 748
Query: 779 GQSKDGDEFNNSIRQLFLAFNMLMD---RPLEEAVKIKGAALKYLPSIINDVKLVFDPVE 835
++ ++F +SI++LF + ++ R E + + A L P+I +++ +F E
Sbjct: 749 CGMEE-EQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQE 807
Query: 836 LSVLFCKFIQSIPDNQLVRQ-----KLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQL 890
++ + S+P + Q KL + + V+S LF SE R +LLP++ + L
Sbjct: 808 VAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHL 867
Query: 891 DDNSNKPDHEASSQLLSNILEVLDRKDVGATAVH-IQLIMERLLRRINRTVIGMNRQSPH 949
+ + S +L +I ++ + A + +++++E LL + +T++ + +S
Sbjct: 868 ---RQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHA 924
Query: 950 ----------------IGSFVACMIALLQQMDDSHYSHYISTFKTRQDIIDFLMETFIMF 993
G +V+C+++LL+QM D+H+ H + F+++ ++ +FL++ F +F
Sbjct: 925 QEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHFQHLLDNFQSKDELKEFLLKIFCVF 984
Query: 994 KDLIGKNVYAKDWMVMNMTQNRVFLRAINQFAEVLTRFFMDQASFELQLWNNYFHLAVAF 1053
++L+ +V+ +DWMVM + + + + + + L + F + F+ ++WN+YF LAV F
Sbjct: 985 RNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTE-TDFDFKVWNSYFSLAVLF 1043
Query: 1054 LTHESLQLETFSQAKRNKIVKKYGDMRKEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVT 1113
+ SLQLE + AKR KI+ KYGDMR + + + MW NLG HKI FIP M+GP L VT
Sbjct: 1044 INQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVT 1103
Query: 1114 LTPEVELRKATIPIFFDMMQCEFNFSGNGNFHMFENELITKLDQEVEGGRGDEQYKVLLE 1173
L P+ E+R IPIF DMM E NGNF E ELI KLD V G+GDE Y+ L
Sbjct: 1104 LVPQPEVRNIMIPIFHDMMDWEQR--KNGNFKQVEAELIDKLDSMVSEGKGDESYRELFS 1161
Query: 1174 KL---------LLEHCRKHKYLSSSGEVFALLVSSLLENLLDYRTIIMQDESKENRMSCT 1224
L LLE + + +G F V+ L+E LLDYR + +E++ ++ CT
Sbjct: 1162 LLTQLFGPYPSLLEKVEQETW-RETGISFVTSVTRLMERLLDYRDCMKGEETENKKIGCT 1220
Query: 1225 VNVLNFYK-EKKREDIYIRYLYKLRDLHRDCENYTEAAYTLLLHAELLQWSDKPCVPHLL 1283
VN++NFYK E +E++YIRY++KL D+H ENYTEAA+TLLL+ ELLQW D+P L
Sbjct: 1221 VNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFL- 1279
Query: 1284 QKDSYYVYTQQELKEKLYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLK 1343
Y T+ + KE L ++II YF+KGK WE I L +ELA YES ++DY+ L + K
Sbjct: 1280 ---HYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYES-LYDYQSLSWIRK 1335
Query: 1344 KRASFYENIIKAMRPQPEYFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSLRLLTQFP 1403
AS+Y+NI++ R +PE+F VG+YG+ FP FLRNK ++ RG +YER E F R+L++FP
Sbjct: 1336 MEASYYDNIMEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFP 1395
Query: 1404 NAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQILNYYRANEVQQFR 1463
A M P + I QY+Q + V P+ + VP+++ ++YR N V++FR
Sbjct: 1396 QAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFR 1455
Query: 1464 YSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEEISPLENAIETME 1523
Y RPF KG KD +NEF ++WIERTT T ++ PGI +WFEV++ E+SPLENAI+ +E
Sbjct: 1456 YDRPFHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVE 1515
Query: 1524 LTNERISNCVQQHAWDR-SLSVHPLSMLLSGIVDPAVMGGFSNYEKAFFTEKYLQEHPED 1582
N+ + + + Q+ + +++ LSM L+G++D AV GG + Y++AFF + Y+ +HP D
Sbjct: 1516 NKNQELRSLISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYINKHPGD 1575
Query: 1583 QEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEKVEKHY-GVIT 1641
EK+ LK L+ Q+ +L G+ +H + + +++PLH++L F+ ++ + + G+
Sbjct: 1576 AEKITQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDK 1635
Query: 1642 LPPNLTERKQSRTGSIVLPYIMSSTLRRLSITSVTSSVVSTSSNSSDNAPSRPGSDGSIL 1701
L P + R + MS +++ +++ T +SS + S S+ +
Sbjct: 1636 LSPACSGTSTPRGNVLASHSPMSPESIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNM 1695
Query: 1702 EPLLERRASSGARVEDL---------SLREENSENRISKFKRKDWSLSKSQVIA-EKAPE 1751
L + S G EDL + R + S +S S S S + + AP
Sbjct: 1696 VMLGD--GSMGDAPEDLYHHMQLAYPNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPS 1753
Query: 1752 PDLMSPTRKAQRPKSL 1767
+ S A+ SL
Sbjct: 1754 QMITSAPSSARGSPSL 1769
>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
Length = 2186
Score = 85.5 bits (210), Expect = 4e-16
Identities = 87/393 (22%), Positives = 173/393 (44%), Gaps = 18/393 (4%)
Query: 1291 YTQQELKEKLYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFYE 1350
Y + L E+LY + + K + +E ++K + +E K D++ L +L Y
Sbjct: 1804 YNENILVEQLYM-CVEFLWKSERYELIADVNKPIIAVFE-KQRDFKKLSDLYYDIHRSYL 1861
Query: 1351 NIIKAMRPQPE----YFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSLRLLTQFPNAE 1406
+ + + + Y+ V +YGQGF K +IY+ + + S RLL + +
Sbjct: 1862 KVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKF 1921
Query: 1407 KMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQILNYYRANEVQQFRYSR 1466
+ + K +PK + V + P +++K + ++ ++ + + +F +
Sbjct: 1922 GADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFET 1981
Query: 1467 PFRKGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEEISPLENAIETMELTN 1526
PF K A RT TT++ FP + K +V S+ E++P+E AI+ M +
Sbjct: 1982 PFTLSGKKHGG-VAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEM---S 2037
Query: 1527 ERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFFTEKYLQEHPEDQEKV 1586
+++S + Q + + L + L G V V G Y +AF E +++P++Q V
Sbjct: 2038 KKVSE-LNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQ--V 2094
Query: 1587 ELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEKVEKHYG-VITLPPN 1645
+LLK + + + ++ + E E L S ++++ ++ IT +
Sbjct: 2095 KLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGRDD 2154
Query: 1646 LTERKQSRTGSIVLPYIMSSTLRRLSITSVTSS 1678
L++R +T + V+ S L S++SS
Sbjct: 2155 LSKRGVDQTCTRVI----SKATPALPTVSISSS 2183
Score = 41.2 bits (95), Expect = 0.010
Identities = 56/267 (20%), Positives = 114/267 (42%), Gaps = 40/267 (14%)
Query: 443 RNDIYVTLIHGEFDKGKK-KTPKNVEVTMSVH--DEEGKLLEKAIH--PGAGYEGISEYK 497
+N IY+ H ++D K +N+ V + DEE K I+ PG + Y
Sbjct: 672 KNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYT 731
Query: 498 SVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVA 550
+V+++ + P + + VK+ + + + HI F+F H +++ + ++ E + G A
Sbjct: 732 AVLHHS-QNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYA 790
Query: 551 FVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFT 610
++ LM +HD + + N +LP + ++ + K+ +
Sbjct: 791 WLPLM----------KHDQIASQEYN-----IPIATSLPPNYLSFQDS--ASGKHGGSDI 833
Query: 611 PSKDSTKDSFQIATLICSTKLTQNVDLLGLLN---------WRSNSQNIKHNLKKLMEVD 661
D K F+++T + ST TQ+ + +S + N + K L+ V+
Sbjct: 834 KWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVE 893
Query: 662 G-GEIVKFLQDTLDALFNIMMEMSDSE 687
I+ FL L+ LF ++++ + E
Sbjct: 894 KIHAIMSFLPIILNQLFKVLVQNEEDE 920
>gi|145699123 dedicator of cytokinesis 11 [Homo sapiens]
Length = 2073
Score = 71.2 bits (173), Expect = 9e-12
Identities = 72/349 (20%), Positives = 149/349 (42%), Gaps = 14/349 (4%)
Query: 1290 VYTQQELKEKLYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFY 1349
V+ +E+ +L ++ + K + +E ++SK + YE + ++E L + + Y
Sbjct: 1688 VHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRR-EFEKLTQVYRTLHGAY 1746
Query: 1350 ENIIKAMRPQPE----YFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSLRLLTQFPNA 1405
I++ M + +F V +YGQ F K +IY+ + + SLRL+ +
Sbjct: 1747 TKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEK 1806
Query: 1406 EKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQILNYYRANEVQQFRYS 1465
+ + K + K+ + V + P + DK + E+ + R + + +F +
Sbjct: 1807 FGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFE 1866
Query: 1466 RPFR-KGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEEISPLENAIETMEL 1524
P+ G+K E RT TT+ +FP + K + + P++ + T E+
Sbjct: 1867 APYTLSGKKQGCIE--EQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPID--VATDEI 1922
Query: 1525 TNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFFTEKYLQEHPEDQE 1584
++ +Q+ + + L + L G V V G Y +AF + ++P +
Sbjct: 1923 KDKTAE--LQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYP--PK 1978
Query: 1585 KVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEKV 1633
KV LK + + + + ++ + E HE L S FR++ +++
Sbjct: 1979 KVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKEL 2027
Score = 38.5 bits (88), Expect = 0.062
Identities = 69/357 (19%), Positives = 144/357 (40%), Gaps = 44/357 (12%)
Query: 443 RNDIYVTLIHGEFDKGKK-KTPKNVEVTMSVHDEE---GKLLEKAIHPGAGYEGISEYKS 498
+N +YV + ++D K +N+ V + D + L+ AG + +
Sbjct: 640 KNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYA 699
Query: 499 VVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVAF 551
VV + + P +Y+ +K+ + I + H+ FTF H + + + +D E G A+
Sbjct: 700 VVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAW 759
Query: 552 VKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTP 611
V L L+DGR ++ ++ + LP + + + E + N+
Sbjct: 760 VPL-------LKDGR--IITFE------QQLPVSANLPPGYLNLNDAESRRQCNV--DIK 802
Query: 612 SKDSTKDSFQIATLICSTKLTQNVDLLGLLNW----RSNSQNIKHNLKKLME----VDGG 663
D K +I + + ST TQ++ + + +S S+ + L K ++ ++
Sbjct: 803 WVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQ 862
Query: 664 EIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKH 723
+++FL L LF ++ M+ D + + + ++ ++ + + L ++I
Sbjct: 863 VMIQFLPVILMQLFRVLTNMTHE---DDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYS 919
Query: 724 F-----SATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYL 775
F SA A + + +A S+ + LK + F I +S YL
Sbjct: 920 FRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYL 976
>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
Length = 2068
Score = 68.9 bits (167), Expect = 4e-11
Identities = 72/364 (19%), Positives = 152/364 (41%), Gaps = 26/364 (7%)
Query: 1290 VYTQQELKEKLYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFY 1349
V+ +++ +L ++ K + +E + K + YE + D+E L +L Y
Sbjct: 1706 VHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRR-DFERLAHLYDTLHRAY 1764
Query: 1350 ENIIKAM----RPQPEYFAVGYYGQ--------------GFPSFLRNKIFIYRGKEYERR 1391
+ + M R YF V ++GQ GF K +IY+ +
Sbjct: 1765 SKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPL 1824
Query: 1392 EDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQIL 1451
+ S RLL + + + + K +PK + V + P + +K + E+
Sbjct: 1825 SEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKT 1884
Query: 1452 NYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEE 1511
+ R++ +++F + PF + K RT T + FP + K V +
Sbjct: 1885 EFERSHNIRRFMFEMPFTQTGKRQGG-VEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTD 1943
Query: 1512 ISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFF 1571
++P+E AI+ M +++++ ++Q + + L + L G V V G Y +AF
Sbjct: 1944 LNPIEVAIDEM---SKKVAE-LRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFL 1999
Query: 1572 TEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKE 1631
+ + +P++ KV+LLK + + + + ++ + E E + + +RE+ +
Sbjct: 2000 DDTNTKRYPDN--KVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAK 2057
Query: 1632 KVEK 1635
++ +
Sbjct: 2058 ELSE 2061
Score = 40.8 bits (94), Expect = 0.013
Identities = 72/350 (20%), Positives = 139/350 (39%), Gaps = 53/350 (15%)
Query: 444 NDIYVTLIHGEFDKGKK-KTPKNVEVTMSVHD--EEGKLLEKAIH--PGAGYEGISEYKS 498
N +YV + ++D K +N+ + + D EE K I+ PG S + +
Sbjct: 640 NHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAA 699
Query: 499 VVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVAF 551
V+++ + P +Y+ +K+ + + + H+ TF H + S + RD E G ++
Sbjct: 700 VLHHH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSW 758
Query: 552 VKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTP 611
+ L+ DG + +H V LP + + EL ++
Sbjct: 759 LPLLK-DGRVVTSEQHIPV--------------SANLPSGYLGYQ--ELGMGRHYGPEIK 801
Query: 612 SKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQN--------IKHNLKKLMEVDGG 663
D K +I+T + ST TQ+ L + +++ + LK L ++G
Sbjct: 802 WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGH 861
Query: 664 EIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKH 723
++ FL L+ LF ++ + E V + +I + Q LE+++
Sbjct: 862 VMIAFLPTILNQLFRVLTRATQEE--------VAVNVTRVIIHVVAQCHEEGLESHL--- 910
Query: 724 FSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVL 773
+YVK + YVA+ + EL + LK F+ +++L
Sbjct: 911 ----RSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLL 956
>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
Length = 2069
Score = 68.9 bits (167), Expect = 4e-11
Identities = 72/364 (19%), Positives = 152/364 (41%), Gaps = 26/364 (7%)
Query: 1290 VYTQQELKEKLYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFY 1349
V+ +++ +L ++ K + +E + K + YE + D+E L +L Y
Sbjct: 1707 VHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRR-DFERLAHLYDTLHRAY 1765
Query: 1350 ENIIKAM----RPQPEYFAVGYYGQ--------------GFPSFLRNKIFIYRGKEYERR 1391
+ + M R YF V ++GQ GF K +IY+ +
Sbjct: 1766 SKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPL 1825
Query: 1392 EDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQIL 1451
+ S RLL + + + + K +PK + V + P + +K + E+
Sbjct: 1826 SEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKT 1885
Query: 1452 NYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEE 1511
+ R++ +++F + PF + K RT T + FP + K V +
Sbjct: 1886 EFERSHNIRRFMFEMPFTQTGKRQGG-VEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTD 1944
Query: 1512 ISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFF 1571
++P+E AI+ M +++++ ++Q + + L + L G V V G Y +AF
Sbjct: 1945 LNPIEVAIDEM---SKKVAE-LRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFL 2000
Query: 1572 TEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKE 1631
+ + +P++ KV+LLK + + + + ++ + E E + + +RE+ +
Sbjct: 2001 DDTNTKRYPDN--KVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAK 2058
Query: 1632 KVEK 1635
++ +
Sbjct: 2059 ELSE 2062
Score = 40.8 bits (94), Expect = 0.013
Identities = 72/350 (20%), Positives = 139/350 (39%), Gaps = 53/350 (15%)
Query: 444 NDIYVTLIHGEFDKGKK-KTPKNVEVTMSVHD--EEGKLLEKAIH--PGAGYEGISEYKS 498
N +YV + ++D K +N+ + + D EE K I+ PG S + +
Sbjct: 641 NHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAA 700
Query: 499 VVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRH-------RSSQETRDKSERAFGVAF 551
V+++ + P +Y+ +K+ + + + H+ TF H + S + RD E G ++
Sbjct: 701 VLHHH-QNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSW 759
Query: 552 VKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKELQASKNLVTFTP 611
+ L+ DG + +H V LP + + EL ++
Sbjct: 760 LPLLK-DGRVVTSEQHIPV--------------SANLPSGYLGYQ--ELGMGRHYGPEIK 802
Query: 612 SKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQN--------IKHNLKKLMEVDGG 663
D K +I+T + ST TQ+ L + +++ + LK L ++G
Sbjct: 803 WVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGH 862
Query: 664 EIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKH 723
++ FL L+ LF ++ + E V + +I + Q LE+++
Sbjct: 863 VMIAFLPTILNQLFRVLTRATQEE--------VAVNVTRVIIHVVAQCHEEGLESHL--- 911
Query: 724 FSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVL 773
+YVK + YVA+ + EL + LK F+ +++L
Sbjct: 912 ----RSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLL 957
>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
Length = 2099
Score = 67.4 bits (163), Expect = 1e-10
Identities = 113/488 (23%), Positives = 185/488 (37%), Gaps = 75/488 (15%)
Query: 1193 FALLVSSLLENL--LDYRTIIMQD--ESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLR 1248
F V LL NL + Y T+ M++ E E M + Y+ D+ + +L +
Sbjct: 1592 FPTQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASP--DLRLTWLQNMA 1649
Query: 1249 DLHRDCENYTEAAYTLLLHAELL-----QWSDKPCVP---------------------HL 1282
+ H + YTEAA L+ A L+ D +P
Sbjct: 1650 EKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESVVSEDT 1709
Query: 1283 LQKDSYYVYTQQELKEK----LYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGL 1338
L D V Q E L ++ F G ++E ++ K + E+ ++ L
Sbjct: 1710 LSPDEDGVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHR-EFRKL 1768
Query: 1339 GNLLKKRASFYENIIKA--MRPQPEYFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSL 1396
K +++I+ R YF VG++G F L + F+Y+ + + S
Sbjct: 1769 TLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFFGSKFGD-LDEQEFVYKEPAITKLPEISH 1827
Query: 1397 RLLTQFPNA------EKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQI 1450
RL + E + +TP + K Y+Q V+P Y D+ +
Sbjct: 1828 RLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEP-------YFDEYEMKDR 1880
Query: 1451 LNYYRAN-EVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQIST 1509
+ Y+ N +++F Y+ PF E P E + T TT + FP I V Q
Sbjct: 1881 VTYFEKNFNLRRFMYTTPFTL-EGRPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEE 1939
Query: 1510 EEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKA 1569
++P+E AIE M+ +++ + Q D + L M+L G V V G +
Sbjct: 1940 FVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKM----LQMVLQGSVGATVNQGPLEVAQV 1995
Query: 1570 FFTE-----KYLQEHPEDQ-----------EKVELLKRLIALQMPLLTEGIRIHGEKLTE 1613
F E K + H + + E VE KRLI + ++ + KL E
Sbjct: 1996 FLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKE 2055
Query: 1614 QLKPLHER 1621
L+P+ ER
Sbjct: 2056 NLRPMIER 2063
Score = 41.6 bits (96), Expect = 0.007
Identities = 64/260 (24%), Positives = 116/260 (44%), Gaps = 32/260 (12%)
Query: 488 AGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQETRDKS-ERA 546
+G E + E + V Y K P +YE VK+ + + H+ FTF H S Q+ + S E
Sbjct: 606 SGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASVETL 665
Query: 547 FGVAFVKLMNPDGTTLQDGRHDLVV---YKGDNKKMEDA-KFYLTLPGTKMEMEEK---- 598
G +++ ++ + LQ G + L V N M A K L P K K
Sbjct: 666 LGYSWLPILLNE--RLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFN 723
Query: 599 -ELQASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLK-K 656
E+QA V+ ++D+ + F +C + +Q + +L+ + + ++H LK
Sbjct: 724 IEVQA----VSSVHTQDNHLEKF---FTLCHSLESQVTFPIRVLDQKISEMALEHELKLS 776
Query: 657 LMEVDGGE---IVKFLQDTLDALFNI----MMEMSDSETYDFLVFDALVFIISLIGD--- 706
++ ++ +V FL LD LF + M+ + + F+++V I + + +
Sbjct: 777 IICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKD 836
Query: 707 -IKFQH-FNPVLETYIYKHF 724
K QH N +L +Y++ F
Sbjct: 837 LSKDQHGRNCLLASYVHYVF 856
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 60.5 bits (145), Expect = 2e-08
Identities = 36/105 (34%), Positives = 46/105 (43%), Gaps = 12/105 (11%)
Query: 1775 SPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPP--------PPPPKSK- 1825
+P ++PP P PPP +SSP G A +P PP PPPP +
Sbjct: 592 APGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 651
Query: 1826 ---PYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
P S T + PP P+ A+ PPPPPP +GIP P
Sbjct: 652 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPP 696
Score = 55.5 bits (132), Expect = 5e-07
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 17/166 (10%)
Query: 1714 RVEDLSLREE--NSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMD 1771
+++DL ++ +SE + +++D SQ+ E A + +K SL
Sbjct: 503 KLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMA--SLSAAA 560
Query: 1772 NRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEG-- 1829
+ P S P P+ P P P + T+ P P PPPPPP P G
Sbjct: 561 ITVPP----SVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 616
Query: 1830 ------SQRNSTELAPPLPVRREAKAPPPPP-PKARKSGIPTSEPG 1868
S T ++PP P+ +A PPPPP P+ P+S PG
Sbjct: 617 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 662
Score = 50.1 bits (118), Expect = 2e-05
Identities = 36/93 (38%), Positives = 40/93 (43%), Gaps = 11/93 (11%)
Query: 1782 PPQS--TPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPP-----PPKSKPYEGSQRNS 1834
PP S + PPP P+ + SPS G A P PP P PP P GS
Sbjct: 634 PPLSGDATIPPPPPLPEGVG-IPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIP 692
Query: 1835 TELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
PP P+ EA PPPPPP GIP P
Sbjct: 693 P---PPPPLPGEAGMPPPPPPLPGGPGIPPPPP 722
Score = 47.8 bits (112), Expect = 1e-04
Identities = 31/89 (34%), Positives = 35/89 (39%), Gaps = 11/89 (12%)
Query: 1780 SSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAP 1839
SS P T + PPP P + R + P G A P PPPP P + P
Sbjct: 658 SSLPGGTAIPPPPPLPGSAR-IPPPPPPLPGSAGIPPPPPPLP----------GEAGMPP 706
Query: 1840 PLPVRREAKAPPPPPPKARKSGIPTSEPG 1868
P P PPPPP GIP PG
Sbjct: 707 PPPPLPGGPGIPPPPPFPGGPGIPPPPPG 735
Score = 37.7 bits (86), Expect = 0.11
Identities = 26/82 (31%), Positives = 33/82 (40%), Gaps = 19/82 (23%)
Query: 1788 LSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREA 1847
++ PP P +P L D + T +PPPP P +ST PP
Sbjct: 561 ITVPPSVPSRAPVPPAPPLPGD--SGTIIPPPPAPG---------DSTTPPPP------- 602
Query: 1848 KAPPPPPPKARKSGIPTSEPGS 1869
PPPPPP G+ S P S
Sbjct: 603 -PPPPPPPPPLPGGVCISSPPS 623
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 60.5 bits (145), Expect = 2e-08
Identities = 36/105 (34%), Positives = 46/105 (43%), Gaps = 12/105 (11%)
Query: 1775 SPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPP--------PPPPKSK- 1825
+P ++PP P PPP +SSP G A +P PP PPPP +
Sbjct: 601 APGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEG 660
Query: 1826 ---PYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
P S T + PP P+ A+ PPPPPP +GIP P
Sbjct: 661 VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPP 705
Score = 55.5 bits (132), Expect = 5e-07
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 17/166 (10%)
Query: 1714 RVEDLSLREE--NSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMD 1771
+++DL ++ +SE + +++D SQ+ E A + +K SL
Sbjct: 512 KLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMA--SLSAAA 569
Query: 1772 NRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEG-- 1829
+ P S P P+ P P P + T+ P P PPPPPP P G
Sbjct: 570 ITVPP----SVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGV 625
Query: 1830 ------SQRNSTELAPPLPVRREAKAPPPPP-PKARKSGIPTSEPG 1868
S T ++PP P+ +A PPPPP P+ P+S PG
Sbjct: 626 CISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG 671
Score = 50.1 bits (118), Expect = 2e-05
Identities = 36/93 (38%), Positives = 40/93 (43%), Gaps = 11/93 (11%)
Query: 1782 PPQS--TPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPP-----PPKSKPYEGSQRNS 1834
PP S + PPP P+ + SPS G A P PP P PP P GS
Sbjct: 643 PPLSGDATIPPPPPLPEGVG-IPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIP 701
Query: 1835 TELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
PP P+ EA PPPPPP GIP P
Sbjct: 702 P---PPPPLPGEAGMPPPPPPLPGGPGIPPPPP 731
Score = 47.8 bits (112), Expect = 1e-04
Identities = 31/89 (34%), Positives = 35/89 (39%), Gaps = 11/89 (12%)
Query: 1780 SSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAP 1839
SS P T + PPP P + R + P G A P PPPP P + P
Sbjct: 667 SSLPGGTAIPPPPPLPGSAR-IPPPPPPLPGSAGIPPPPPPLP----------GEAGMPP 715
Query: 1840 PLPVRREAKAPPPPPPKARKSGIPTSEPG 1868
P P PPPPP GIP PG
Sbjct: 716 PPPPLPGGPGIPPPPPFPGGPGIPPPPPG 744
Score = 37.7 bits (86), Expect = 0.11
Identities = 26/82 (31%), Positives = 33/82 (40%), Gaps = 19/82 (23%)
Query: 1788 LSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREA 1847
++ PP P +P L D + T +PPPP P +ST PP
Sbjct: 570 ITVPPSVPSRAPVPPAPPLPGD--SGTIIPPPPAPG---------DSTTPPPP------- 611
Query: 1848 KAPPPPPPKARKSGIPTSEPGS 1869
PPPPPP G+ S P S
Sbjct: 612 -PPPPPPPPPLPGGVCISSPPS 632
>gi|157426887 dedicator of cytokinesis 6 [Homo sapiens]
Length = 2047
Score = 55.8 bits (133), Expect = 4e-07
Identities = 70/293 (23%), Positives = 116/293 (39%), Gaps = 28/293 (9%)
Query: 1300 LYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFYENIIKAM--- 1356
L ++ YF G ++E ++ K L E+ DY+ L + K + I+
Sbjct: 1686 LLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHR-DYKKLAAVHGKLQEAFTKIMHQSSGW 1744
Query: 1357 -RPQPEYFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSLRLLTQFPN------AEKMT 1409
R YF VG+YG F L + F+Y+ + + S RL + E +
Sbjct: 1745 ERVFGTYFRVGFYGAHFGD-LDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIK 1803
Query: 1410 STTPPGEDIKSSPKQYMQCFTVKPVMSLPPSYKDKPVPEQILNYYRANEVQQFRYSRPFR 1469
+ P + S K Y+Q V+P +Y+ K +++ + R ++ F + PF
Sbjct: 1804 DSNPVDKSKLDSQKAYIQITYVEPYFD---TYELK---DRVTYFDRNYGLRTFLFCTPFT 1857
Query: 1470 KGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEEISPLENAIETMELTNERI 1529
+ E +T +T + FP I V ++P+E AIE M+ +
Sbjct: 1858 PDGR-AHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTREL 1916
Query: 1530 SNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFFTEKYLQEHPED 1582
+ +Q D + L M+L G V P V G + F L E PED
Sbjct: 1917 AFATEQDPPDAKM----LQMVLQGSVGPTVNQGPLEVAQVF-----LAEIPED 1960
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 55.5 bits (132), Expect = 5e-07
Identities = 39/125 (31%), Positives = 53/125 (42%), Gaps = 10/125 (8%)
Query: 1750 PEPDLMSPTRKAQRPKSL---QLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSL 1806
P P PT P S+ + + +L+P H P PL PP P +SP+
Sbjct: 225 PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQ 284
Query: 1807 QTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLP-VRREAKAPPPPPPKARKSGIPTS 1865
PP PPP PY ++ APPLP V ++ PPP PPK+ P
Sbjct: 285 DAQE------PPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQ 338
Query: 1866 EPGSQ 1870
+ G+Q
Sbjct: 339 KAGAQ 343
Score = 48.1 bits (113), Expect = 8e-05
Identities = 36/119 (30%), Positives = 48/119 (40%), Gaps = 12/119 (10%)
Query: 1748 KAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSS---PPQSTPLSPPPLTPKATRTLSSP 1804
+AP P L + T S HG++ PP+ +PPP TP P
Sbjct: 129 RAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPP 188
Query: 1805 SLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIP 1863
L + TP+ PP P +K N +APP+P A PPPPPP +P
Sbjct: 189 PLPSSSPIKTPLVSPPGPLTK------GNLPVVAPPVPC---APPPPPPPPPPTPPPLP 238
Score = 46.2 bits (108), Expect = 3e-04
Identities = 41/138 (29%), Positives = 57/138 (41%), Gaps = 25/138 (18%)
Query: 1739 LSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDN------RLSPFHGSSPPQSTPLSPPP 1792
L + V+++KA +P L +P P L L+ + P + Q P PPP
Sbjct: 237 LPPASVLSDKAVKPQL-APLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPP 295
Query: 1793 LTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPP 1852
L P A+ SP A+ P PP P S S+E PPLP + + PP
Sbjct: 296 LPPYAS---CSPR------ASLPAPPLPGVNS---------SSETPPPLPPKSPSFQAPP 337
Query: 1853 PPPKARKSGIPTSEPGSQ 1870
A+ P + PGSQ
Sbjct: 338 QKAGAQALPAPPAPPGSQ 355
Score = 45.8 bits (107), Expect = 4e-04
Identities = 41/126 (32%), Positives = 53/126 (42%), Gaps = 26/126 (20%)
Query: 1756 SPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPL-----------SPPPLTPKATRTLSSP 1804
SP + AQ P + L P+ SP S P +PPPL PK+ + P
Sbjct: 281 SPAQDAQEPPA---PPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPP 337
Query: 1805 SLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPT 1864
Q G A P PP PP S+P+ +R+ P K PPP P AR PT
Sbjct: 338 --QKAGAQALPAPPAPPG-SQPFLQKKRHGR------PGAGGGKLNPPPAPPARS---PT 385
Query: 1865 SEPGSQ 1870
+E S+
Sbjct: 386 TELSSK 391
Score = 41.6 bits (96), Expect = 0.007
Identities = 33/104 (31%), Positives = 39/104 (37%), Gaps = 15/104 (14%)
Query: 1781 SPPQSTPLSPPPL---TPKATRTLSSPSLQTDG----------IAATPVPPPPPPKSKPY 1827
+PP P PPPL +P T +S P T G A P PPPPPP P
Sbjct: 178 TPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPL 237
Query: 1828 EGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIP--TSEPGS 1869
+ S + P PPP P G P +EP S
Sbjct: 238 PPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPAS 281
Score = 38.1 bits (87), Expect = 0.081
Identities = 22/51 (43%), Positives = 23/51 (45%), Gaps = 16/51 (31%)
Query: 1815 PVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTS 1865
PVPPPPPP P PP P+ APPPPPP A TS
Sbjct: 2 PVPPPPPPPLPP------------PPPPL----GAPPPPPPSAPPVSTDTS 36
Score = 35.4 bits (80), Expect = 0.53
Identities = 31/132 (23%), Positives = 47/132 (35%), Gaps = 30/132 (22%)
Query: 1750 PEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTD 1809
P P++ +P P L P SSP ++ +SPP K + +P +
Sbjct: 167 PRPNVPAPPPPTPPPPPPPLPP----PLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCA 222
Query: 1810 GIAATPVPPPPPPKSKPYEGSQRNSTE----------LAPPLPV---------------- 1843
P PPP PP P + + + PPLP+
Sbjct: 223 PPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASP 282
Query: 1844 RREAKAPPPPPP 1855
++A+ PP PPP
Sbjct: 283 AQDAQEPPAPPP 294
Score = 32.0 bits (71), Expect = 5.8
Identities = 21/67 (31%), Positives = 25/67 (37%), Gaps = 5/67 (7%)
Query: 1803 SPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGI 1862
SP L I+ +PP P E + APP P APPPP P +
Sbjct: 132 SPRLPNKTISGPLIPPASPRLGNTSEA--HGAARTAPPRP---NVPAPPPPTPPPPPPPL 186
Query: 1863 PTSEPGS 1869
P P S
Sbjct: 187 PPPLPSS 193
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 54.3 bits (129), Expect = 1e-06
Identities = 33/103 (32%), Positives = 40/103 (38%), Gaps = 15/103 (14%)
Query: 1766 SLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSK 1825
+LQ M+ S + PP + PPP P +LS A P+PPPPPP
Sbjct: 630 ALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP--- 686
Query: 1826 PYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEPG 1868
PPLP A PPPPPP + PG
Sbjct: 687 ------------PPPLPPPSSAGPPPPPPPPPLPNSPAPPNPG 717
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 54.3 bits (129), Expect = 1e-06
Identities = 40/112 (35%), Positives = 52/112 (46%), Gaps = 12/112 (10%)
Query: 1750 PEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPP---PLTPKATRTLSSPSL 1806
P L +P+ +A ++ L+ SP SPP P SPP P++P AT PS
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSP--PPSPPVQAPFSPPASPPVSPSAT----PPSQ 469
Query: 1807 QTDGIAATPVP-PPPPPKSKPYEGSQRNSTELAPPL--PVRREAKAPPPPPP 1855
+AA P+ PP PP S P S + PPL P + AK PP PP
Sbjct: 470 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 41/98 (41%), Gaps = 9/98 (9%)
Query: 1782 PPQSTPLSPP---PLTPKATRTLSSPSLQTDGIAATPV-PPPPPPKSKPYE--GSQRNST 1835
PP P SPP PL+P AT + +P+ + P PPP PP P+ S S
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
Query: 1836 ELAPPLPVRREAKAPP---PPPPKARKSGIPTSEPGSQ 1870
PP APP PP P A P++ P Q
Sbjct: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500
Score = 44.7 bits (104), Expect = 9e-04
Identities = 33/96 (34%), Positives = 43/96 (44%), Gaps = 12/96 (12%)
Query: 1774 LSPFHGSSPPQSTPLSPPPLTP--KATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQ 1831
L+P S+PP L PP TP +AT +L SP+LQ + P PP P + P +
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH-SFLPSPPLSPLATPPPQ--- 395
Query: 1832 RNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
APP +APP PP S + T P
Sbjct: 396 ------APPALALPPLQAPPSPPASPPLSPLATPSP 425
Score = 43.9 bits (102), Expect = 0.001
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 20/133 (15%)
Query: 1749 APEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQST----------PLSPPPLTPKAT 1798
A P S T +Q P SL ++ P +SPP S PL+ PPL
Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
Query: 1799 RTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPP--K 1856
+ P+L T + A P PP P P+ S LP+ A PP PP
Sbjct: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPS--------ASLPMSPLATPPPQAPPVLA 567
Query: 1857 ARKSGIPTSEPGS 1869
A +P S P S
Sbjct: 568 APLLQVPPSPPAS 580
Score = 43.1 bits (100), Expect = 0.003
Identities = 44/147 (29%), Positives = 60/147 (40%), Gaps = 29/147 (19%)
Query: 1739 LSKSQVIAEKAPEPDLMSPTRKAQRPKS---------LQLMDNRLSPFHGS---SPPQST 1786
+S S +AP P P + A+ P LQ + + + F G SP S
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550
Query: 1787 PLSP---PPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNST---ELAPP 1840
P+SP PP P+A L++P LQ PP PP S + +R T + +
Sbjct: 551 PMSPLATPP--PQAPPVLAAPLLQV---------PPSPPASPTLQAPRRPPTPGPDTSVS 599
Query: 1841 LPVRREAKAPPPPPPKARKSGIPTSEP 1867
P A AP PPPP +R S P
Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLSGP 626
Score = 38.1 bits (87), Expect = 0.081
Identities = 64/276 (23%), Positives = 91/276 (32%), Gaps = 43/276 (15%)
Query: 1598 PLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSI 1657
PL +G+RI E+ + K S + T P + R ++ +
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 1658 VLPYIMSSTLRRLSITSVTSSVVSTSSNS----SDNAPSRPGSDGSILEPLLERRASSGA 1713
LP S R SV S S +S S A RP + G + P +SS
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 1714 RVEDLSLREENSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTRKAQ-RPKSLQLMDN 1772
+ S ++S A P +P +Q +PK LQ +
Sbjct: 248 PLS---------------------SPARSGPSARGTPR----APAHPSQPKPKGLQAL-- 280
Query: 1773 RLSPFHGSSPPQSTPL---SPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEG 1829
PPQ TP + P L P ++ L++PS + P P P S
Sbjct: 281 --------RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332
Query: 1830 SQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTS 1865
LAPP P + P PP S TS
Sbjct: 333 QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Score = 33.9 bits (76), Expect = 1.5
Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 14/95 (14%)
Query: 1783 PQSTPLSPPPLTPKATRTLSS-------PSLQTDGIAATPVPPPPPPKSKPYEGSQRNST 1835
P +P PPP+TP A R L + P + G P P++ P + +S
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 1836 ELA--PPLPVRREAKAPPPPPPKARKSGIPTSEPG 1868
A PP R E PP S P S PG
Sbjct: 89 NPASRPPASGRGER-----APPAKNTSPGPVSSPG 118
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 54.3 bits (129), Expect = 1e-06
Identities = 40/112 (35%), Positives = 52/112 (46%), Gaps = 12/112 (10%)
Query: 1750 PEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPP---PLTPKATRTLSSPSL 1806
P L +P+ +A ++ L+ SP SPP P SPP P++P AT PS
Sbjct: 377 PLSPLATPSPQAPNALAVHLLQAPFSP--PPSPPVQAPFSPPASPPVSPSAT----PPSQ 430
Query: 1807 QTDGIAATPVP-PPPPPKSKPYEGSQRNSTELAPPL--PVRREAKAPPPPPP 1855
+AA P+ PP PP S P S + PPL P + AK PP PP
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482
Score = 52.4 bits (124), Expect = 4e-06
Identities = 70/282 (24%), Positives = 103/282 (36%), Gaps = 26/282 (9%)
Query: 1598 PLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSI 1657
PL +G+RI E+ + K S + T P + R ++ +
Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 178
Query: 1658 VLPYIMSSTLRRLSITSVTSSVVSTSSNS----SDNAPSRPGSDGSILEPLLERRASSGA 1713
LP S R SV S S +S S A RP + G + P +SS
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238
Query: 1714 RVEDLSLREENSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNR 1773
+ + ++ R S+ + +A P ++P RK P L +
Sbjct: 239 PLSSPARSGPSARGT----PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294
Query: 1774 LS------PFHGSSPPQSTPLSPPPLTP--KATRTLSSPSLQTDGIAATPVPPPPPPKSK 1825
L+ P S+PP L PP TP +AT +L SP+LQ + P PP P +
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH-SFLPSPPLSPLATP 353
Query: 1826 PYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
P + APP +APP PP S + T P
Sbjct: 354 PPQ---------APPALALPPLQAPPSPPASPPLSPLATPSP 386
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 41/98 (41%), Gaps = 9/98 (9%)
Query: 1782 PPQSTPLSPP---PLTPKATRTLSSPSLQTDGIAATPV-PPPPPPKSKPYE--GSQRNST 1835
PP P SPP PL+P AT + +P+ + P PPP PP P+ S S
Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423
Query: 1836 ELAPPLPVRREAKAPP---PPPPKARKSGIPTSEPGSQ 1870
PP APP PP P A P++ P Q
Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461
Score = 43.9 bits (102), Expect = 0.001
Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 20/133 (15%)
Query: 1749 APEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQST----------PLSPPPLTPKAT 1798
A P S T +Q P SL ++ P +SPP S PL+ PPL
Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476
Query: 1799 RTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPP--K 1856
+ P+L T + A P PP P P+ S LP+ A PP PP
Sbjct: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPS--------ASLPMSPLATPPPQAPPVLA 528
Query: 1857 ARKSGIPTSEPGS 1869
A +P S P S
Sbjct: 529 APLLQVPPSPPAS 541
Score = 43.1 bits (100), Expect = 0.003
Identities = 44/147 (29%), Positives = 60/147 (40%), Gaps = 29/147 (19%)
Query: 1739 LSKSQVIAEKAPEPDLMSPTRKAQRPKS---------LQLMDNRLSPFHGS---SPPQST 1786
+S S +AP P P + A+ P LQ + + + F G SP S
Sbjct: 452 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 511
Query: 1787 PLSP---PPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNST---ELAPP 1840
P+SP PP P+A L++P LQ PP PP S + +R T + +
Sbjct: 512 PMSPLATPP--PQAPPVLAAPLLQV---------PPSPPASPTLQAPRRPPTPGPDTSVS 560
Query: 1841 LPVRREAKAPPPPPPKARKSGIPTSEP 1867
P A AP PPPP +R S P
Sbjct: 561 GPRLTLALAPGPPPPPSRSPSSTLSGP 587
Score = 34.3 bits (77), Expect = 1.2
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 21/94 (22%)
Query: 1783 PQSTPLSPPPLTPKATRTLSSPSL--------QTDGIAATPVPPPPPPKSKPYEGSQRNS 1834
P +P PPP+TP A R L + + GI + P+S P G R S
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI-----PESAPRAGPTRTS 83
Query: 1835 TELAPPLPVRREAKAPPPPPPKARKSGIPTSEPG 1868
PP R E PP S P S PG
Sbjct: 84 ---RPPASGRGER-----APPAKNTSPGPVSSPG 109
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 53.9 bits (128), Expect = 1e-06
Identities = 36/104 (34%), Positives = 44/104 (42%), Gaps = 15/104 (14%)
Query: 1770 MDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSS----PSLQTDGIAATPVPPPP----- 1820
+ R + H +P L+PPP T + LS+ P+ A P PPPP
Sbjct: 276 LPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNG 335
Query: 1821 ----PPKSKPYE--GSQRNSTELAPPLPVRREAKAPPPPPPKAR 1858
PP PY GS+ S PP P R A PPPPPP R
Sbjct: 336 ARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLR 379
Score = 41.6 bits (96), Expect = 0.007
Identities = 47/183 (25%), Positives = 68/183 (37%), Gaps = 35/183 (19%)
Query: 1710 SSGARVEDLSLREENSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTRKAQRPKSLQL 1769
SS A + +L + S + R + + S + AP P P R+A P +
Sbjct: 140 SSRASLPELPRMQRPS---LPDLSRPNTTSSTGMKHSSSAPPPP--PPGRRANAPPTPLP 194
Query: 1770 MDNRLSPFHGSSPP------------QSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVP 1817
M + +P + P + P +PPP+ P SP G + +
Sbjct: 195 MHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPP-----SPVNIRTGPSGQSLA 249
Query: 1818 PPPPPKSKP---YEGSQRNSTELAPPLPVRREA---KAP-------PPPPPKARKSGIPT 1864
PPPPP +P G + E AP LP R + K P PPPP A S +
Sbjct: 250 PPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSN 309
Query: 1865 SEP 1867
P
Sbjct: 310 RPP 312
Score = 37.0 bits (84), Expect = 0.18
Identities = 57/230 (24%), Positives = 76/230 (33%), Gaps = 42/230 (18%)
Query: 1652 SRTGSIVLPYIMSSTLRRLSITSVTSSVVSTSSNSSDNAPSRPGSDGSILEPLLERRASS 1711
SR LP + +L LS + TSS S+S+ P PG RRA++
Sbjct: 141 SRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPP-PG-----------RRANA 188
Query: 1712 GARVEDLSLREENSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMD 1771
+ + + NR K + Q + P P + P ++
Sbjct: 189 PPTPLPMHSSKAPAYNR-----EKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNI---- 239
Query: 1772 NRLSPFHGSSPPQSTPLSPPPLTPKATRTLSS------PSLQTDGIAATPVP-----PPP 1820
R P S P P PP P + ++ P TP P PPP
Sbjct: 240 -RTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPP 298
Query: 1821 PPKSKPYEGSQRNSTELAPPLPVR---REAKAPPPPPPKARKSGIPTSEP 1867
P + P S R PP P R APPPPPP R P
Sbjct: 299 PTSASPSLLSNR------PPPPARDPPSRGAAPPPPPPVIRNGARDAPPP 342
Score = 34.7 bits (78), Expect = 0.90
Identities = 36/128 (28%), Positives = 44/128 (34%), Gaps = 18/128 (14%)
Query: 1742 SQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPP--QSTPLSPPPLTPKATR 1799
S+ A P P + + R A P M P G PP TP PPP P R
Sbjct: 320 SRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLR 379
Query: 1800 TLSSPSLQT---------DGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAP 1850
S+ T + PV P P+ Y+ QR P R A+
Sbjct: 380 NGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEE--YKHFQR-----IYPSKTNRAARGA 432
Query: 1851 PPPPPKAR 1858
PP PP R
Sbjct: 433 PPLPPILR 440
Score = 33.1 bits (74), Expect = 2.6
Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 20/84 (23%)
Query: 1804 PSLQTDGI-AATPVPPPPPPKSKPYEGSQRNSTELA-------PPLP------------V 1843
P+LQ AA P PP +P + + + L P LP +
Sbjct: 111 PALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGM 170
Query: 1844 RREAKAPPPPPPKARKSGIPTSEP 1867
+ + APPPPPP R + PT P
Sbjct: 171 KHSSSAPPPPPPGRRANAPPTPLP 194
>gi|4758666 LATS homolog 1 [Homo sapiens]
Length = 1130
Score = 53.5 bits (127), Expect = 2e-06
Identities = 53/225 (23%), Positives = 93/225 (41%), Gaps = 15/225 (6%)
Query: 1641 TLPPNLTERKQSRTGSIVLPYIMSSTLRRLSITSVTSSVVSTSSNSSDNAPSRPGSDGSI 1700
+L P E SR+ S V P ++ + + ++N S A S S
Sbjct: 84 SLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVIQALQKTNNRSIEAAIEFISKMSY 143
Query: 1701 LEPLLERRASSGARVEDLSLREENSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTRK 1760
+P E+ A++ AR + S++ N + +++ ++ W SK ++ ++ P S
Sbjct: 144 QDPRREQMAAAAARPINASMKPGNVQQSVNR--KQSWKGSKESLVPQRHGPPLGESVAYH 201
Query: 1761 AQRPKSLQ-----LMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSL---QTDGIA 1812
++ P S L + +S F + P ++PPP P R+++ P QT
Sbjct: 202 SESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPP--PPQVRSVTPPPPPRGQTPPPR 259
Query: 1813 ATPVPPP---PPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPP 1854
T PPP P ++K Y G+ P+P + PPPP
Sbjct: 260 GTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPP 304
Score = 39.7 bits (91), Expect = 0.028
Identities = 36/131 (27%), Positives = 49/131 (37%), Gaps = 32/131 (24%)
Query: 1757 PTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTD------- 1809
P + +P ++Q NR + GS PPL SP+ QTD
Sbjct: 158 PINASMKPGNVQQSVNRKQSWKGSKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSG 217
Query: 1810 -GIAA---------TPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARK 1859
GI+A V PPPPP+ + + PP P R + PPP+
Sbjct: 218 SGISAFVQAHPSNGQRVNPPPPPQVR----------SVTPPPPPRGQT-----PPPRGTT 262
Query: 1860 SGIPTSEPGSQ 1870
P+ EP SQ
Sbjct: 263 PPPPSWEPNSQ 273
Score = 33.5 bits (75), Expect = 2.0
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 6/93 (6%)
Query: 1770 MDNRLSPFHGSSPPQST--PLSPPPLT-PKATRTLSSPSLQTDGIAATPVPPPPPPKS-- 1824
+ NR S S P +T ++P P+ P + + P LQT P P P ++
Sbjct: 469 LGNRASHSANSQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQ 528
Query: 1825 -KPYEGSQRNSTELAPPLPVRREAKAPPPPPPK 1856
P+ ++ + PP+ + PPPP PK
Sbjct: 529 PSPFPEGTASNVTVMPPVAEAPNYQGPPPPYPK 561
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 52.8 bits (125), Expect = 3e-06
Identities = 40/124 (32%), Positives = 55/124 (44%), Gaps = 12/124 (9%)
Query: 1750 PEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPP---PLTPKATRTLSSPSL 1806
P L +P+ +A ++ L+ SP SPP P SPP P++P AT PS
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSP--PPSPPVQAPFSPPASPPVSPSAT----PPSQ 694
Query: 1807 QTDGIAATPVP-PPPPPKSKPYEGSQRNSTELAPPL--PVRREAKAPPPPPPKARKSGIP 1863
+AA P+ PP PP S P S + PPL P + +PP PP + + P
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754
Query: 1864 TSEP 1867
P
Sbjct: 755 PRVP 758
Score = 47.4 bits (111), Expect = 1e-04
Identities = 35/122 (28%), Positives = 46/122 (37%), Gaps = 15/122 (12%)
Query: 1749 APEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQT 1808
A P S T +Q P SL ++ P +SPP S +PPP P
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP----------- 729
Query: 1809 DGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEPG 1868
+AA P+ PP P + P PPL + PP PP S P ++P
Sbjct: 730 --LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS--PLAKPP 785
Query: 1869 SQ 1870
Q
Sbjct: 786 PQ 787
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 41/98 (41%), Gaps = 9/98 (9%)
Query: 1782 PPQSTPLSPP---PLTPKATRTLSSPSLQTDGIAATPV-PPPPPPKSKPYE--GSQRNST 1835
PP P SPP PL+P AT + +P+ + P PPP PP P+ S S
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687
Query: 1836 ELAPPLPVRREAKAPP---PPPPKARKSGIPTSEPGSQ 1870
PP APP PP P A P++ P Q
Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Score = 43.1 bits (100), Expect = 0.003
Identities = 70/300 (23%), Positives = 104/300 (34%), Gaps = 35/300 (11%)
Query: 1598 PLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSI 1657
PL +G+RI E+ + K S + T P + R ++ +
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 1658 VLPYIMSSTLRRLSITSVTSSVVSTSSNS----SDNAPSRPGSDGSILEPLLERRASSG- 1712
LP S R SV S S +S S A RP + G + P +SS
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 1713 -----ARVEDLSLREENSENRISKFKRKDWSLSKSQVIA----EKAP------EPDLMSP 1757
AR + + S+ K K + + + AP L +P
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 1758 TRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVP 1817
+ + + + DN +P + PP +P PL P + + PSLQT P P
Sbjct: 308 SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS--APPSLQT-----LPSP 360
Query: 1818 PPPPPKSKPYEGS-----QRNSTELAPPLPVRREAKAP---PPPPPKARKSGIPTSEPGS 1869
P PP P + S + PP+ V +P PP P A S T+ GS
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
Score = 42.0 bits (97), Expect = 0.006
Identities = 43/136 (31%), Positives = 54/136 (39%), Gaps = 19/136 (13%)
Query: 1742 SQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSP---PPLTPKAT 1798
SQ A P + P+ A P S +P ++PP P SP PP++P AT
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752
Query: 1799 RTLSSPSLQTDGIAATPVP-PPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPP----P 1853
P L +AA P+ PP PP S P + LA P P A A PP P
Sbjct: 753 PPPRVPPL----LAAPPLQVPPSPPASLP-------MSPLAKPPPQAPPALATPPLQALP 801
Query: 1854 PPKARKSGIPTSEPGS 1869
P A G P +
Sbjct: 802 SPPASFPGQAPFSPSA 817
Score = 41.6 bits (96), Expect = 0.007
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 9/120 (7%)
Query: 1755 MSPTRKA--QRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIA 1812
MSP K Q P +L + P +S P P SP P + L++P Q +
Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP--LATPPPQAPPVL 835
Query: 1813 ATPV--PPPPPPKSKPYEGSQRNST---ELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
A P+ PP PP S + +R T + + P A AP PPPP +R S P
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
Score = 40.8 bits (94), Expect = 0.013
Identities = 38/125 (30%), Positives = 50/125 (40%), Gaps = 11/125 (8%)
Query: 1748 KAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQ 1807
+AP L +P + P S+ + P S P Q P PPL+P AT +P
Sbjct: 570 QAPPSPLTTPP--PETPSSIATPPPQAPPALASPPLQGLP--SPPLSPLATPPPQAPPX- 624
Query: 1808 TDGIAATPVP-PPPPPKSKPYEGSQRNSTELAPPLPVR--REAKAPPPPPPKARKSGIPT 1864
+A P+ PP PP S P S + L V + +PPP PP P
Sbjct: 625 ---LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 1865 SEPGS 1869
S P S
Sbjct: 682 SPPVS 686
Score = 40.4 bits (93), Expect = 0.016
Identities = 41/141 (29%), Positives = 55/141 (39%), Gaps = 23/141 (16%)
Query: 1749 APEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQT 1808
A P S T Q P L ++ P +SPP S +PPP P L++P LQ
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL---LAAPPLQV 768
Query: 1809 DGI--AATPVPP--PPPPKSKPYEGSQRNSTELAPP--------------LPVRREAKAP 1850
A+ P+ P PPP++ P + +PP LP+ A P
Sbjct: 769 PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828
Query: 1851 PPPPP--KARKSGIPTSEPGS 1869
P PP A +P S P S
Sbjct: 829 PQAPPVLAAPLLQVPPSPPAS 849
Score = 38.1 bits (87), Expect = 0.081
Identities = 36/130 (27%), Positives = 45/130 (34%), Gaps = 14/130 (10%)
Query: 1752 PDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTP-LSPPPLTPKA-----TRTLSSPS 1805
P L +P P L P +S P +TP L PP L++P
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP 580
Query: 1806 LQTDGIAATPVPPPPPP-KSKPYEG-------SQRNSTELAPPLPVRREAKAPPPPPPKA 1857
+T ATP P PP S P +G APP +APP PP
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640
Query: 1858 RKSGIPTSEP 1867
S + T P
Sbjct: 641 PLSPLATPSP 650
Score = 36.2 bits (82), Expect = 0.31
Identities = 34/117 (29%), Positives = 46/117 (39%), Gaps = 19/117 (16%)
Query: 1752 PDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTP-KATRTLSSPSLQTDG 1810
P + +P +A P SLQ + P +SP P SP L+ +AT +L SP+LQ
Sbjct: 370 PSMTTPPMQA--PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427
Query: 1811 IAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
T P ++ L P R A PP PP +P S P
Sbjct: 428 SFLTMSP-------------RQTQASLTSP---SRPASTPPDSPPLQAPLSLPASPP 468
Score = 33.9 bits (76), Expect = 1.5
Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 14/95 (14%)
Query: 1783 PQSTPLSPPPLTPKATRTLSS-------PSLQTDGIAATPVPPPPPPKSKPYEGSQRNST 1835
P +P PPP+TP A R L + P + G P P++ P + +S
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 1836 ELA--PPLPVRREAKAPPPPPPKARKSGIPTSEPG 1868
A PP R E PP S P S PG
Sbjct: 89 NPASRPPASGRGER-----APPAKNTSPGPVSSPG 118
>gi|54112429 dedicator of cytokinesis 7 [Homo sapiens]
Length = 2109
Score = 51.6 bits (122), Expect = 7e-06
Identities = 66/285 (23%), Positives = 114/285 (40%), Gaps = 25/285 (8%)
Query: 1300 LYQEIISYFDKGKMWEKAIKLSKELAETYESKVFDYEGLGNLLKKRASFYENIIKAM--- 1356
L ++ + F M+E ++ K L +E+ D + L + K + I+
Sbjct: 1746 LLEQAAASFSMAGMYEAVNEVYKVLIPIHEANR-DAKKLSTIHGKLQEAFSKIVHQSTGW 1804
Query: 1357 -RPQPEYFAVGYYGQGFPSFLRNKIFIYRGKEYERREDFSLRLLTQF-----PNAEKMTS 1410
R YF VG+YG F L + F+Y+ + + S RL + + ++
Sbjct: 1805 ERMFGTYFRVGFYGTKFGD-LDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIK 1863
Query: 1411 TTPPGEDIKSSP-KQYMQCFTVKPVMSLPPSYKDKPVPEQILNYYRAN-EVQQFRYSRPF 1468
+ P + K P K Y+Q V+P Y D + + Y+ N +++F Y PF
Sbjct: 1864 DSNPVDKCKLDPNKAYIQITYVEP-------YFDTYEMKDRITYFDKNYNLRRFMYCTPF 1916
Query: 1469 RKGEKDPDNEFATMWIERTTYTTAYTFPGILKWFEVKQISTEEISPLENAIETMELTNER 1528
+ E + +T TT++ FP I V ++P+E AIE M+ +
Sbjct: 1917 TLDGR-AHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQE 1975
Query: 1529 ISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVMGGFSNYEKAFFTE 1573
++ Q D + L M+L G V V G + F +E
Sbjct: 1976 LAFATHQDPADPKM----LQMVLQGSVGTTVNQGPLEVAQVFLSE 2016
Score = 32.0 bits (71), Expect = 5.8
Identities = 44/195 (22%), Positives = 82/195 (42%), Gaps = 18/195 (9%)
Query: 496 YKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQETRDKS-ERAFGVAFVKL 554
Y +VVY+ + P ++E +KV + H+ FTF H S Q+ ++ E G ++ +
Sbjct: 616 YTAVVYHN-RSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPM 674
Query: 555 MNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLT----LPGTKMEMEEKELQASKNLVTFT 610
+ L+ G+ L V +K A L+ LPG K K + N+
Sbjct: 675 L--QNGRLKTGQFCLPV---SLEKPPQAYSVLSPEVPLPGMKWVDNHKGV---FNVEVVA 726
Query: 611 PSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKLMEVDGGE----IV 666
S T+D + L +++ + + + R N+++ LK + +V
Sbjct: 727 VSSIHTQDPYLDKFFALVNALDEHLFPVRIGDMRIMENNLENELKSSISALNSSQLEPVV 786
Query: 667 KFLQDTLDALFNIMM 681
+FL LD L +++
Sbjct: 787 RFLHLLLDKLILLVI 801
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 49.7 bits (117), Expect = 3e-05
Identities = 73/321 (22%), Positives = 111/321 (34%), Gaps = 90/321 (28%)
Query: 1578 EHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHERLSSCFRELKEKVEKHY 1637
+HP+ Q+K + +K L + L + + +G ++ + K L+ ++E ++ E Y
Sbjct: 471 KHPQIQKKSQYIKYLCCDDVRTLHQWV--NGIRIAKYGKQLYMN----YQEALKRTESAY 524
Query: 1638 GVITLPPNLTERKQSRTGSIVLPYIMSSTLRRLSITSVTSSVVSTSSNSSDNAPSRPGSD 1697
+L SS+++ S +S S SN SD+ S
Sbjct: 525 DWTSLS--------------------SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPA 564
Query: 1698 GSILEPLLERRASSGARVEDLSLREENSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSP 1757
G + + S A L EE+S+ R+ R SL + +P+P +++P
Sbjct: 565 GHVRSQSIVSSVFSEAWKRGTQL-EESSKARMESMNRPYTSL-----VPPLSPQPKIVTP 618
Query: 1758 TRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAA---- 1813
+Q L PP P PPP P L S S + G AA
Sbjct: 619 YTASQPSPPLP-------------PPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFV 665
Query: 1814 ----------------------TP-------------------VPPPPPPKSKPYEGSQR 1832
TP VPPPPPP P GS
Sbjct: 666 KYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAM 725
Query: 1833 NSTELAPPLPVRREAKAPPPP 1853
+ AP P + APPPP
Sbjct: 726 AQLKPAPCAPSLPQFSAPPPP 746
Score = 47.4 bits (111), Expect = 1e-04
Identities = 40/143 (27%), Positives = 53/143 (37%), Gaps = 22/143 (15%)
Query: 1738 SLSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKA 1797
+L K Q K P P +SP + + Q P S P + P + P +P A
Sbjct: 839 TLPKQQSFCAKPP-PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897
Query: 1798 TRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKA 1857
+ + + + PPPPP S + PP P PPPPPP A
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVF-----------PPPPPSPVPAPPPPPPPTA 946
Query: 1858 R----KSGIP------TSEPGSQ 1870
KSG P TS PG +
Sbjct: 947 SPTPDKSGSPGKKTSKTSSPGGK 969
Score = 42.4 bits (98), Expect = 0.004
Identities = 28/82 (34%), Positives = 35/82 (42%), Gaps = 8/82 (9%)
Query: 1776 PFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKP-YEGSQRNS 1834
P PPQ+ P P P T T + + T TP PP PP K +P + S
Sbjct: 768 PIPAPLPPQAPP-KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826
Query: 1835 TELAPPLPVRREAKAPPPPPPK 1856
+ PP+PV PPP PK
Sbjct: 827 SPPTPPVPV------PPPTLPK 842
Score = 37.7 bits (86), Expect = 0.11
Identities = 33/118 (27%), Positives = 46/118 (38%), Gaps = 9/118 (7%)
Query: 1750 PEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTD 1809
P P + +P PK L + S + P T +PP TP P+
Sbjct: 765 PPPPIPAPLPPQAPPKPLVTIPAPTST--KTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS 822
Query: 1810 GIAATP------VPPPPPPKSKPYEGSQRNSTELAPPLPVRREA-KAPPPPPPKARKS 1860
I +P VPPP PK + + S P V++ A + PPPP P A +S
Sbjct: 823 YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMES 880
Score = 37.0 bits (84), Expect = 0.18
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 24/75 (32%)
Query: 1791 PPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAP 1850
PPL+P+ P + T A+ P PP PPP P PP P P
Sbjct: 607 PPLSPQ-------PKIVTPYTASQPSPPLPPPPPPP------------PPPP-----PPP 642
Query: 1851 PPPPPKARKSGIPTS 1865
PPPPP P++
Sbjct: 643 PPPPPPLPSQSAPSA 657
Score = 34.7 bits (78), Expect = 0.90
Identities = 41/149 (27%), Positives = 56/149 (37%), Gaps = 33/149 (22%)
Query: 1748 KAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTP------LSPPPLTPKATRTL 1801
K P P +M ++ +P+ L + N + P PP TP L P P P +
Sbjct: 685 KPPTPPVMQS--QSVKPQIL-VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFS 741
Query: 1802 SSP------SLQTDGIAATPVPPPP-----------PPKSKPYEGSQRNSTELAPPLPVR 1844
+ P +Q A P PPPP PPK + ST+ P+ +
Sbjct: 742 APPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAP-TSTKTVAPVVTQ 800
Query: 1845 REAKAPPPPPPKARK------SGIPTSEP 1867
P PP P A+K S IP S P
Sbjct: 801 AAPPTPTPPVPPAKKQPAFPASYIPPSPP 829
Score = 31.6 bits (70), Expect = 7.6
Identities = 27/101 (26%), Positives = 36/101 (35%), Gaps = 25/101 (24%)
Query: 1782 PPQSTPLSPPPLTPKATRT---LSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELA 1838
PP P PPP P A+ T SP +T ++ PPP + S ++S+
Sbjct: 931 PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQR--NSSIKSSSGAE 988
Query: 1839 PPLPVR--------------------REAKAPPPPPPKARK 1859
P P R +E PP PPK K
Sbjct: 989 HPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGK 1029
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 49.3 bits (116), Expect = 4e-05
Identities = 39/132 (29%), Positives = 50/132 (37%), Gaps = 24/132 (18%)
Query: 1739 LSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPL-SPPPLTPKA 1797
L+ + + P P L P+ + L++ + P + PP TP PPP P
Sbjct: 1424 LAPAAAVPGPPPLPGL--PSANSNGTPEPPLLEEKPPP---TPPPAPTPQPQPPPPPPPP 1478
Query: 1798 TRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKA 1857
L SP +A TP PPPPP PP P PPPPPP A
Sbjct: 1479 QPALPSPPPL---VAPTPSSPPPPP---------------LPPPPPPAMPSPPPPPPPAA 1520
Query: 1858 RKSGIPTSEPGS 1869
P EP +
Sbjct: 1521 APLAAPPEEPAA 1532
Score = 42.0 bits (97), Expect = 0.006
Identities = 42/161 (26%), Positives = 58/161 (36%), Gaps = 22/161 (13%)
Query: 1730 SKFKRKDWSLSKS--QVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHG---SSPPQ 1784
S KR D L ++ + + + E D ++ R Q S + P G +S P
Sbjct: 1361 SPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPD 1420
Query: 1785 STPLSPPPLTPKATRTLSSPSLQTDGI----------------AATPVPPPPPPKSKPYE 1828
PL+P P PS ++G A TP P PPPP P +
Sbjct: 1421 GPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPP-Q 1479
Query: 1829 GSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEPGS 1869
+ + L P P PPPPP A S P P +
Sbjct: 1480 PALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAA 1520
Score = 40.0 bits (92), Expect = 0.021
Identities = 33/113 (29%), Positives = 41/113 (36%), Gaps = 25/113 (22%)
Query: 1744 VIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSS 1803
++ EK P +PT + Q P PPQ SPPPL +
Sbjct: 1452 LLEEKPPPTPPPAPTPQPQPPPP-------------PPPPQPALPSPPPLVAPTPSSPPP 1498
Query: 1804 PSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPK 1856
P L A P PPPPPP + + APP E AP P P+
Sbjct: 1499 PPLPPPPPPAMPSPPPPPPPAA--------APLAAPP----EEPAAPSPEDPE 1539
Score = 37.7 bits (86), Expect = 0.11
Identities = 27/79 (34%), Positives = 32/79 (40%), Gaps = 13/79 (16%)
Query: 1789 SPPPLTPKATRTLSSPS---LQTDGIAATPVPPPPPPK---------SKPYEGSQRNSTE 1836
SPPP P A T +P L+ G V PPPPP+ P + +
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVH 822
Query: 1837 LAPPLPVRREAKAPPPPPP 1855
L P R A PPPPPP
Sbjct: 823 LLEP-ATRDGAPQPPPPPP 840
Score = 36.6 bits (83), Expect = 0.24
Identities = 38/137 (27%), Positives = 48/137 (35%), Gaps = 44/137 (32%)
Query: 1757 PTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPP-PLTPKATRTLSSPSLQTDGIAATP 1815
P R++ + K N +S S+PP P PP P TP+ T T P QT T
Sbjct: 1673 PVRRSGQAK------NPVSAGGSSAPPPKAPAPPPKPETPEKT-TSEKPPEQT---PETA 1722
Query: 1816 VPPPPPPK--------------------SKPYEGSQRNSTELAPP-------------LP 1842
+P PP P+ +P G + S P LP
Sbjct: 1723 MPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLP 1782
Query: 1843 VRREAKAPPPPPPKARK 1859
R K PPPK RK
Sbjct: 1783 KARPTKVKAEPPPKKRK 1799
Score = 36.2 bits (82), Expect = 0.31
Identities = 28/93 (30%), Positives = 36/93 (38%), Gaps = 8/93 (8%)
Query: 1776 PFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKS---KPYEGSQR 1832
P G+ PP P + P P S +T G+ P PP P + +P Q
Sbjct: 974 PKAGAGPPPGPP-AYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQS 1032
Query: 1833 NSTELAPPLPVRREAKAPPPPPPKARKSGIPTS 1865
+ APP P PPPP P + G TS
Sbjct: 1033 GPHQAAPPPP----PPPPPPPAPASEPKGGLTS 1061
Score = 34.7 bits (78), Expect = 0.90
Identities = 27/92 (29%), Positives = 32/92 (34%), Gaps = 6/92 (6%)
Query: 1782 PPQSTPL------SPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNST 1835
PPQ P SP P K L P+ + P PPPPPP + S
Sbjct: 798 PPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSH 857
Query: 1836 ELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
L P P R PP A + + EP
Sbjct: 858 GLEPAAPSPRLRPEESLDPPGAMQELLGALEP 889
Score = 32.7 bits (73), Expect = 3.4
Identities = 33/121 (27%), Positives = 42/121 (34%), Gaps = 34/121 (28%)
Query: 1764 PKSLQLMDNRLSPFHGSSPPQSTPLSP-------PPLTPKATRTLSSPSLQTDGIAAT-- 1814
P SL L D PF SPP + LSP P P +L L G+
Sbjct: 165 PSSLSLQD---PPF---SPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAG 218
Query: 1815 ------------PVPPPPPPKSKPYE-------GSQRNSTELAPPLPVRREAKAPPPPPP 1855
P PPPPP+ P + + + E + P AP PPPP
Sbjct: 219 LGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPP 278
Query: 1856 K 1856
+
Sbjct: 279 E 279
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 48.9 bits (115), Expect = 5e-05
Identities = 37/127 (29%), Positives = 49/127 (38%), Gaps = 14/127 (11%)
Query: 1752 PDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLT---PKATRTLSSPSLQT 1808
P +P+ P + L P SPP +T +PPP T P T T S P++ T
Sbjct: 1534 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITT 1593
Query: 1809 DGIAATPVPPP-------PPPKSKPYEGSQRNSTELAPPLPVRR-EAKAPPPPPPKARKS 1860
T P P PPP + P S +T + PP P PPP +
Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTP---SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1650
Query: 1861 GIPTSEP 1867
PT+ P
Sbjct: 1651 PPPTTTP 1657
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/124 (26%), Positives = 44/124 (35%), Gaps = 14/124 (11%)
Query: 1754 LMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLT---PKATRTLSSPSLQTDG 1810
+ +P+ P L P SPP +T +PPP T P T T + P
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP----- 1450
Query: 1811 IAATPVPP-----PPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTS 1865
TP PP PPP + P + S P P PPP + + P +
Sbjct: 1451 -TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509
Query: 1866 EPGS 1869
P S
Sbjct: 1510 PPAS 1513
Score = 44.3 bits (103), Expect = 0.001
Identities = 31/118 (26%), Positives = 41/118 (34%), Gaps = 9/118 (7%)
Query: 1750 PEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTD 1809
P P +P+ P P SPP +TP++PP T T + T
Sbjct: 1470 PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT 1529
Query: 1810 GIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
P P PP + P + ST PP P PPP + PT+ P
Sbjct: 1530 TTTPPPTTTPSPPTTTPI--TPPTSTTTLPP-------TTTPSPPPTTTTTPPPTTTP 1578
Score = 43.9 bits (102), Expect = 0.001
Identities = 39/130 (30%), Positives = 51/130 (39%), Gaps = 20/130 (15%)
Query: 1752 PDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLT---PKATRTLSSP-SLQ 1807
P +P+ P + L P SPP +T +PPP T P T ++ P S
Sbjct: 1495 PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1554
Query: 1808 TDGIAATPVPPP-----PPPKSKPYEGSQRNSTELAPPLPVRREAKAPPP-----PPPKA 1857
T TP PPP PPP + P S +T +PP PPP PP
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPTTTP---SPPTTTTPSPPTIT---TTTPPPTTTPSPPTTT 1608
Query: 1858 RKSGIPTSEP 1867
+ PT+ P
Sbjct: 1609 TTTPPPTTTP 1618
Score = 43.5 bits (101), Expect = 0.002
Identities = 33/128 (25%), Positives = 47/128 (36%), Gaps = 15/128 (11%)
Query: 1752 PDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGI 1811
P +P+ P + L P SPP +T +PPP T + T ++PS I
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS---PPI 1669
Query: 1812 AATPVPPPPPPKSKPYEGS-QRNSTELAPPLPVRR-----------EAKAPPPPPPKARK 1859
T PPP S P + +T + P P + P PPP
Sbjct: 1670 TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMT 1729
Query: 1860 SGIPTSEP 1867
+ PT+ P
Sbjct: 1730 TPSPTTTP 1737
Score = 42.4 bits (98), Expect = 0.004
Identities = 35/108 (32%), Positives = 46/108 (42%), Gaps = 22/108 (20%)
Query: 1781 SPPQSTPLSPPPLT---PKATRTLSSP-SLQTDGIAATPVPPP-----PPPKSKPYEGSQ 1831
SPP +T +PPP T P T ++ P S T TP PPP PPP + P S
Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP---SP 1659
Query: 1832 RNSTELAPPL------PVRREAKAP----PPPPPKARKSGIPTSEPGS 1869
+T +PP+ P +P P PP + PT+ P S
Sbjct: 1660 PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS 1707
Score = 40.0 bits (92), Expect = 0.021
Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 1780 SSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAP 1839
++PP +T SPP TP T SP T P P PP + P ++T L P
Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSPPTTTT-TTPPPTTTPSPPTTTPIT-PPASTTTLPP 1519
Query: 1840 ---PLPVRREAKAPPPPPPKARKSGIPTSEPGS 1869
P P PPP + + P + P S
Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1552
Score = 39.3 bits (90), Expect = 0.036
Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 6/89 (6%)
Query: 1781 SPPQSTPLSPPP-LTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAP 1839
SPP ST +PPP TP T SP T T PPP + S +T + P
Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP----SPPTTTPITP 1510
Query: 1840 PLPVRR-EAKAPPPPPPKARKSGIPTSEP 1867
P P PP + PT+ P
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTP 1539
Score = 36.2 bits (82), Expect = 0.31
Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 11/127 (8%)
Query: 1750 PEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPL----TPKATRTLSSP- 1804
P P +P+ +L P ++ P T PP+ TP T T S P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 1805 -SLQTDGIAATPVPP---PPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKS 1860
+ T TP PP P PP + P +T PP P PP + +
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTP--SPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516
Query: 1861 GIPTSEP 1867
PT+ P
Sbjct: 1517 LPPTTTP 1523
Score = 34.7 bits (78), Expect = 0.90
Identities = 27/107 (25%), Positives = 40/107 (37%), Gaps = 9/107 (8%)
Query: 1742 SQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLT----PKA 1797
S + +P M+ P S S SPP +T +P P T P
Sbjct: 1683 SPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTT 1742
Query: 1798 TRTLSSPSLQTDGIAATPVPPP-PPPKSKPYEGSQRNSTELAPPLPV 1843
T T P+ + + TP+PP PP P+ +T P +P+
Sbjct: 1743 TMTTLPPTTTSSPLTTTPLPPSITPPTFSPFS----TTTPTTPCVPL 1785
Score = 34.3 bits (77), Expect = 1.2
Identities = 31/105 (29%), Positives = 39/105 (37%), Gaps = 14/105 (13%)
Query: 1779 GSSPPQSTPLSP-----PPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRN 1833
G+ P +TP++ P TP T+T T IA PPP S P +
Sbjct: 4169 GTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS 4228
Query: 1834 -----STELAPPLP--VRREAKAPP--PPPPKARKSGIPTSEPGS 1869
ST L LP + + APP P P G S P S
Sbjct: 4229 SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPS 4273
Score = 33.1 bits (74), Expect = 2.6
Identities = 40/171 (23%), Positives = 62/171 (36%), Gaps = 11/171 (6%)
Query: 1660 PYIMSSTLRRLSITSVTSSVVSTSSNSSDNAPSRPGSDGSILEPLLERRASSGARVEDLS 1719
P ++T+ + T + +T ++ P G+ P +S A + +L+
Sbjct: 4154 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTH---TSTAPIAELT 4210
Query: 1720 LREENSENRISKFKRKDWS-LSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFH 1778
E+ + R S L++S + P M+ T P S S H
Sbjct: 4211 TSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTA----PPSTPTAPTTTSGGH 4266
Query: 1779 GSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPV---PPPPPPKSKP 1826
SPP ST SPP + T T SS + + T P P P S P
Sbjct: 4267 TLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTP 4317
Score = 32.0 bits (71), Expect = 5.8
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 19/90 (21%)
Query: 1782 PPQSTPLSP---PPLTPKATRTLSSP---------SLQTDGIAATPVPPP-----PPPKS 1824
PP +TP SP P P T T SP + T TP PPP P P +
Sbjct: 1676 PPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTT 1735
Query: 1825 KPYEGSQRNSTELAPPLPVRREAKAPPPPP 1854
P + +T PP P PP
Sbjct: 1736 TPSPPTTTMTT--LPPTTTSSPLTTTPLPP 1763
Score = 31.2 bits (69), Expect = 9.9
Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 8/92 (8%)
Query: 1781 SPPQSTPLSP-----PPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNST 1835
+PP +TP++ P TP T+T ++ + T T P P P ++ + +T
Sbjct: 1894 TPPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTT 1950
Query: 1836 ELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
P P + P P + PT P
Sbjct: 1951 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1982
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 48.9 bits (115), Expect = 5e-05
Identities = 49/158 (31%), Positives = 69/158 (43%), Gaps = 18/158 (11%)
Query: 1722 EENSENRISKFKRKDWSLSKSQVIAE-KAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGS 1780
E+NS+ K K + S S+S+ + ++ P P R+ + R SP
Sbjct: 262 EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP 321
Query: 1781 SPPQSTP---LSPPPL-----TPKATRTLSSPSLQTDGIAATPV----PPPPPPK--SKP 1826
SP + TP + PPP +P R SS SL +++ PP PPK S P
Sbjct: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381
Query: 1827 YEGSQRNSTELAPPLPVRREAKAPPP-PPPKARKSGIP 1863
++R S +PP RR +PP PPPK R S P
Sbjct: 382 PRKTRRLSPSASPPR--RRHRPSPPATPPPKTRHSPTP 417
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/108 (30%), Positives = 44/108 (40%), Gaps = 8/108 (7%)
Query: 1756 SPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATP 1815
SP+ + ++ ++ R SP S PP SP P P R +P + TP
Sbjct: 530 SPSPRKRQKETSPRGRRRRSP---SPPPTRRRRSPSPAPPPRRRRTPTPPPRR----RTP 582
Query: 1816 VPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIP 1863
PPP P S +P P +R + PPPPPK R S P
Sbjct: 583 SPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTAS-PPPPPKRRASPSP 629
Score = 40.4 bits (93), Expect = 0.016
Identities = 63/255 (24%), Positives = 93/255 (36%), Gaps = 42/255 (16%)
Query: 1646 LTERKQSRTGSIVLPYIMSSTLRRLSITSVTSSVVSTSSNSSDNAPSRPGSDGSILEPLL 1705
L+E ++ + G + + + +SS +SS+S D P R +
Sbjct: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVG--- 518
Query: 1706 ERRASSGARVEDLSLREENSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTRKAQRP- 1764
RR S +R S R+ E +R+ S ++ +P P P R+ + P
Sbjct: 519 RRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAP----PPRRRRTPT 574
Query: 1765 -----KSLQLMDNRLSPF-HGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPP 1818
++ R SP SPP SP P P RT S P A+P PP
Sbjct: 575 PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSP--PPKRRTASPPPPPKR--RASPSPP 630
Query: 1819 P-------PPPK---------------SKPYEGSQ--RNSTELAPPLPVRREAKAPPPPP 1854
P PPPK SK +GS R++ E P P +R + +P P
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
Query: 1855 PKARKSGIPTSEPGS 1869
P+ S P S
Sbjct: 691 PQTSSSPPPVRRGAS 705
Score = 40.0 bits (92), Expect = 0.021
Identities = 47/155 (30%), Positives = 70/155 (45%), Gaps = 31/155 (20%)
Query: 1729 ISKFKRKDWSLSKSQVIAEKAPEPDLM-SPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTP 1787
+S RK S S+S A ++P+P+ SP+ RP++ Q + G+S
Sbjct: 656 LSSKHRKGSSPSRSTREA-RSPQPNKRHSPS---PRPRAPQTSSSPPPVRRGASSSPQRR 711
Query: 1788 LSPPPLT-----------PKATRTLSSPSLQT-------DGIAATPVP----PPPPPKSK 1825
SP P T PK + +SPS Q+ ++ +P P PP PP
Sbjct: 712 QSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPS-- 769
Query: 1826 PYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKS 1860
P + SQ ST +P +PV++ AK+P P P R S
Sbjct: 770 PVQ-SQSPSTNWSPAVPVKK-AKSPTPSPSPPRNS 802
Score = 35.0 bits (79), Expect = 0.69
Identities = 39/128 (30%), Positives = 52/128 (40%), Gaps = 21/128 (16%)
Query: 1756 SPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLT---PKATRTLSSPSLQTDGIA 1812
SP R+ +R S L + S SS +S P PP T P+ TR LS PS
Sbjct: 343 SPVRRRRR-SSASLSGSSSSS--SSSRSRSPPKKPPKRTSSPPRKTRRLS-PSASPPRRR 398
Query: 1813 ATPVPPP-PPPKSKPYEGSQRNSTELAPPLPVR-------------REAKAPPPPPPKAR 1858
P PP PPPK++ Q+++ + V E + P P PK R
Sbjct: 399 HRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR 458
Query: 1859 KSGIPTSE 1866
K + SE
Sbjct: 459 KVELSESE 466
Score = 34.7 bits (78), Expect = 0.90
Identities = 59/258 (22%), Positives = 106/258 (41%), Gaps = 21/258 (8%)
Query: 1609 EKLTEQLKPLHERLSSCFRELKEKVE-KHYGVITLPPNLTERKQSRTG---SIVLPYIMS 1664
+KL +QLK + C L++KV+ + + P +T+R G +V+ +I +
Sbjct: 22 KKLLKQLK-----FAEC---LEKKVDMSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFN 73
Query: 1665 STLRRLSITSVTSSVVSTSSNSSDNAPSRPGSDGSILEPLLERRAS-SGARVEDLSLREE 1723
+L + + S ++ + N + G + LL + + +G L L++E
Sbjct: 74 ----QLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKE 129
Query: 1724 NSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRL-SPFHGSSP 1782
+ R + + K S+ K +K + + S K +R +S + +R SP SSP
Sbjct: 130 EIKQRQIE-QEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSP 188
Query: 1783 PQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLP 1842
+ +P+ SPS + TP P P K K E S + +T + L
Sbjct: 189 VRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVK--EPSVQEATSTSDILK 246
Query: 1843 VRREAKAPPPPPPKARKS 1860
V + P P P K+
Sbjct: 247 VPKPEPIPEPKEPSPEKN 264
Score = 33.1 bits (74), Expect = 2.6
Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 3/83 (3%)
Query: 1748 KAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPP-PLTPKATRTLSSPSL 1806
+ PEP + P+S++ + + S P P +PP P+ ++ T SP++
Sbjct: 726 RTPEPKKIKKAASPS-PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAV 784
Query: 1807 QTDGIAATPVPPPPPPKSKPYEG 1829
A +P P P PP++ EG
Sbjct: 785 PVKK-AKSPTPSPSPPRNSDQEG 806
Score = 32.7 bits (73), Expect = 3.4
Identities = 34/123 (27%), Positives = 47/123 (38%), Gaps = 16/123 (13%)
Query: 1745 IAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFH--GSSPPQSTPLSPPPLTPKATRTLS 1802
++ P SP K + P LS H GSSP +ST + P K R
Sbjct: 635 VSHSPPPKQRSSPVTKRRSPS--------LSSKHRKGSSPSRSTREARSPQPNK--RHSP 684
Query: 1803 SPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGI 1862
SP + +++P P S P QR + P+RR ++ P P K S
Sbjct: 685 SPRPRAPQTSSSPPPVRRGASSSP----QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Query: 1863 PTS 1865
P S
Sbjct: 741 PQS 743
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 47.8 bits (112), Expect = 1e-04
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 3/117 (2%)
Query: 1752 PDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGI 1811
P P+ KA + + + F + + P PL P R ++P + +G
Sbjct: 1167 PKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEG- 1225
Query: 1812 AATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEPG 1868
P PP PPP + + + R+S L PP R AK P K S PG
Sbjct: 1226 --QPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPG 1280
Score = 36.2 bits (82), Expect = 0.31
Identities = 36/133 (27%), Positives = 55/133 (41%), Gaps = 16/133 (12%)
Query: 1740 SKSQVIAEKAPEPDL--MSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKA 1797
+ +V+A AP P + + A PK+ +SP P S L P K
Sbjct: 872 TNGKVLAATAPTPGIPILQSVPSAPPPKA-----QSVSPVQAPPPGGSAQLLPG----KV 922
Query: 1798 TRTLSSPSLQT-DGIAATPVPPPPPPKSKPYEGSQRNSTEL--APPLPVRREAKAPPPPP 1854
L++PS+ G A P+P PP S P + + +++ P+PV + PP
Sbjct: 923 LVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLS 982
Query: 1855 PKARKSGIPTSEP 1867
P PTS+P
Sbjct: 983 PATLPG--PTSQP 993
Score = 36.2 bits (82), Expect = 0.31
Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 22/108 (20%)
Query: 1767 LQLMDNRLSPFHGSSPPQSTPLSPPPL-TPKATRTLSSPSLQTDGIAATPVPPPPPPKSK 1825
L++ + R ++P + P + PL P T T ++P A TP P P +
Sbjct: 1509 LKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAP-------APTPSPAGGPDPTS 1561
Query: 1826 PYEGSQRNSTELAPPLPVRREA------------KAPPPPPPKARKSG 1861
P S + + APPLP E+ +PPPP P +G
Sbjct: 1562 P--SSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATG 1607
Score = 33.9 bits (76), Expect = 1.5
Identities = 39/129 (30%), Positives = 50/129 (38%), Gaps = 27/129 (20%)
Query: 1749 APEPDLMS-PTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSS--PS 1805
APE +L PT A P + +P SSPP P + + K T++S PS
Sbjct: 1218 APESELEGQPTPPAPPP-----LPETWTPTARSSPPLPPP-AEERTSAKGPETMASKFPS 1271
Query: 1806 LQTD-----------GIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREA------- 1847
+D G TP P P P P S+ +S A P R+EA
Sbjct: 1272 SSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKV 1331
Query: 1848 KAPPPPPPK 1856
K PPP K
Sbjct: 1332 KVRPPPLKK 1340
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 47.8 bits (112), Expect = 1e-04
Identities = 45/200 (22%), Positives = 70/200 (35%), Gaps = 36/200 (18%)
Query: 1700 ILEPLLERRASSGARVEDLSLREENSENRISKFKRKDWSLSKSQVIAEKAPEPDLMSPTR 1759
+ E L + S A++ +L + + + + + +S S + + + PEP+ +P
Sbjct: 411 LTERLRDAENESMAKIAELEKQLSQARKELETLRER-FSESTAMGASRRPPEPE-KAPPA 468
Query: 1760 KAQRPKSLQLMDNRL--------------------------SPFHGSSPPQSTPLSPP-- 1791
RP +L+L L +P G +P P P
Sbjct: 469 APTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSP 528
Query: 1792 ---PLTPKATRTLSSPSLQTDGIAATP-VPPPPPPKSKPYEGSQRNSTELAPPLPVRREA 1847
P A P G+ + PP PP++ P GS APPLP
Sbjct: 529 DLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPP--APPLPGDLPP 586
Query: 1848 KAPPPPPPKARKSGIPTSEP 1867
PPPPPP +P P
Sbjct: 587 PPPPPPPPPGTDGPVPPPPP 606
Score = 44.3 bits (103), Expect = 0.001
Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 7/71 (9%)
Query: 1775 SPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNS 1834
SP +PP L PPP P P TDG P PPPPPP P + R
Sbjct: 571 SPEPPPAPPLPGDLPPPPPPPP-------PPPGTDGPVPPPPPPPPPPPGGPPDALGRRD 623
Query: 1835 TELAPPLPVRR 1845
+EL P + ++
Sbjct: 624 SELGPGVKAKK 634
Score = 43.5 bits (101), Expect = 0.002
Identities = 30/101 (29%), Positives = 36/101 (35%), Gaps = 24/101 (23%)
Query: 1776 PFHGSSPPQSTPL--------SPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPY 1827
P G++PP PL +PP P+A SP +PPPPPP
Sbjct: 536 PAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPP----- 590
Query: 1828 EGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPTSEPG 1868
PP P + PPPPPP G P G
Sbjct: 591 -----------PPPPPGTDGPVPPPPPPPPPPPGGPPDALG 620
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 47.4 bits (111), Expect = 1e-04
Identities = 36/163 (22%), Positives = 69/163 (42%), Gaps = 20/163 (12%)
Query: 1721 REENSENRISKFKRKDWSLSKSQVIAEKAPEPDLM---SPTRKAQRPKSLQLMDNRLSPF 1777
++E K K+ S+ K+ V + + P P +P + + P + ++ +
Sbjct: 1215 KKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEG 1274
Query: 1778 HGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPP----------------PPP 1821
+ S+P + + P + K+++ +S P+L T PP PPP
Sbjct: 1275 NVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPP 1334
Query: 1822 PKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGIPT 1864
P+S P E S++ P +PV+++ K PPP ++ T
Sbjct: 1335 PESGP-EQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGT 1376
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 47.4 bits (111), Expect = 1e-04
Identities = 31/94 (32%), Positives = 36/94 (38%), Gaps = 8/94 (8%)
Query: 1776 PFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPP--KSKPYEGSQRN 1833
P HG+ + P T SP+ + +P PPPPPP S S R
Sbjct: 283 PMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRA 342
Query: 1834 STELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
S PP PV PPPPPP A P P
Sbjct: 343 SMTSTPPPPV------PPPPPPPATALQAPAVPP 370
Score = 43.5 bits (101), Expect = 0.002
Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 17/95 (17%)
Query: 1769 LMDNR-LSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPY 1827
L++NR SP G +P +P PPP P LS+ SL+ + P P PPPP
Sbjct: 303 LIENRPQSPATGRTPVFVSPTPPPP-PPPLPSALSTSSLRASMTSTPPPPVPPPP----- 356
Query: 1828 EGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGI 1862
PP + PPPP P G+
Sbjct: 357 ----------PPPATALQAPAVPPPPAPLQIAPGV 381
Score = 42.0 bits (97), Expect = 0.006
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 23/120 (19%)
Query: 1764 PKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATP------VP 1817
P LQ+ L P +PP P++PP + P ++P +T + P +P
Sbjct: 372 PAPLQIAPGVLHP----APP---PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLP 424
Query: 1818 PPPPPKSKPYEGSQRNS----TELA-PPLPVRREAKAPPPP-----PPKARKSGIPTSEP 1867
PPPPP P G + +S T LA PP + P P PP IP SEP
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484
Score = 32.0 bits (71), Expect = 5.8
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 14/78 (17%)
Query: 1782 PPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATP----------VPPPPPPKSKPYEGSQ 1831
PP PL PP + P + T+++ + G+ TP +PP PP + P +
Sbjct: 426 PPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPK 485
Query: 1832 RNSTELAPPLPVRREAKA 1849
R+ + LPV +A++
Sbjct: 486 RHPS----TLPVISDARS 499
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 47.4 bits (111), Expect = 1e-04
Identities = 31/94 (32%), Positives = 36/94 (38%), Gaps = 8/94 (8%)
Query: 1776 PFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPP--KSKPYEGSQRN 1833
P HG+ + P T SP+ + +P PPPPPP S S R
Sbjct: 283 PMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRA 342
Query: 1834 STELAPPLPVRREAKAPPPPPPKARKSGIPTSEP 1867
S PP PV PPPPPP A P P
Sbjct: 343 SMTSTPPPPV------PPPPPPPATALQAPAVPP 370
Score = 43.5 bits (101), Expect = 0.002
Identities = 30/95 (31%), Positives = 39/95 (41%), Gaps = 17/95 (17%)
Query: 1769 LMDNR-LSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATPVPPPPPPKSKPY 1827
L++NR SP G +P +P PPP P LS+ SL+ + P P PPPP
Sbjct: 303 LIENRPQSPATGRTPVFVSPTPPPP-PPPLPSALSTSSLRASMTSTPPPPVPPPP----- 356
Query: 1828 EGSQRNSTELAPPLPVRREAKAPPPPPPKARKSGI 1862
PP + PPPP P G+
Sbjct: 357 ----------PPPATALQAPAVPPPPAPLQIAPGV 381
Score = 42.0 bits (97), Expect = 0.006
Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 23/120 (19%)
Query: 1764 PKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATP------VP 1817
P LQ+ L P +PP P++PP + P ++P +T + P +P
Sbjct: 372 PAPLQIAPGVLHP----APP---PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLP 424
Query: 1818 PPPPPKSKPYEGSQRNS----TELA-PPLPVRREAKAPPPP-----PPKARKSGIPTSEP 1867
PPPPP P G + +S T LA PP + P P PP IP SEP
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484
Score = 32.0 bits (71), Expect = 5.8
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 14/78 (17%)
Query: 1782 PPQSTPLSPPPLTPKATRTLSSPSLQTDGIAATP----------VPPPPPPKSKPYEGSQ 1831
PP PL PP + P + T+++ + G+ TP +PP PP + P +
Sbjct: 426 PPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPK 485
Query: 1832 RNSTELAPPLPVRREAKA 1849
R+ + LPV +A++
Sbjct: 486 RHPS----TLPVISDARS 499
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,749,080
Number of Sequences: 37866
Number of extensions: 3478718
Number of successful extensions: 31262
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 943
Number of HSP's that attempted gapping in prelim test: 18987
Number of HSP's gapped (non-prelim): 7185
length of query: 1870
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1753
effective length of database: 13,817,196
effective search space: 24221544588
effective search space used: 24221544588
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.