Search of human proteins with 116734691

Search of human proteins with 116734691

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo
sapiens]
         (511 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo sa...  1030   0.0  
gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo sap...  1019   0.0  
gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]           489   e-138
gi|38524591 intramembrane protease 5 [Homo sapiens]                   485   e-137
gi|33413418 signal peptide peptidase 3 [Homo sapiens]                 109   7e-24
gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo ...    86   1e-16
gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo ...    86   1e-16
gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo ...    86   1e-16
gi|21040269 ring finger protein 133 [Homo sapiens]                     34   0.28 
gi|29789407 ring finger protein 149 [Homo sapiens]                     34   0.36 
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [...    34   0.36 
gi|14150090 chromosome 2 open reading frame 7 [Homo sapiens]           33   0.81 
gi|37588871 ring finger protein 128 isoform 2 [Homo sapiens]           32   1.4  
gi|157694503 solute carrier family 14 (urea transporter), member...    31   2.3  
gi|37675277 ring finger protein 148 [Homo sapiens]                     31   2.3  
gi|29788758 ring finger protein 130 [Homo sapiens]                     31   2.3  
gi|58331204 ring finger protein 150 [Homo sapiens]                     31   3.1  
gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens]        30   4.0  

>gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo
           sapiens]
          Length = 511

 Score = 1030 bits (2663), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS 60
           MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS
Sbjct: 1   MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS 60

Query: 61  KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR 120
           KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR
Sbjct: 61  KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR 120

Query: 121 ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI 180
           ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI
Sbjct: 121 ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI 180

Query: 181 MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL 240
           MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL
Sbjct: 181 MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL 240

Query: 241 YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL 300
           YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL
Sbjct: 241 YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL 300

Query: 301 ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI 360
           ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI
Sbjct: 301 ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI 360

Query: 361 FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG 420
           FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG
Sbjct: 361 FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG 420

Query: 421 DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC 480
           DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC
Sbjct: 421 DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC 480

Query: 481 TLVTSCAVALWRRELGVFWTGSGFAVNTSLL 511
           TLVTSCAVALWRRELGVFWTGSGFAVNTSLL
Sbjct: 481 TLVTSCAVALWRRELGVFWTGSGFAVNTSLL 511


>gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo
           sapiens]
          Length = 592

 Score = 1019 bits (2636), Expect = 0.0
 Identities = 505/505 (100%), Positives = 505/505 (100%)

Query: 1   MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS 60
           MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS
Sbjct: 1   MAAAVAAALARLLAAFLLLAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLS 60

Query: 61  KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR 120
           KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR
Sbjct: 61  KASFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR 120

Query: 121 ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI 180
           ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI
Sbjct: 121 ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFI 180

Query: 181 MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL 240
           MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL
Sbjct: 181 MAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLL 240

Query: 241 YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL 300
           YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL
Sbjct: 241 YYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLL 300

Query: 301 ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI 360
           ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI
Sbjct: 301 ALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDI 360

Query: 361 FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG 420
           FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG
Sbjct: 361 FFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLGFG 420

Query: 421 DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC 480
           DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC
Sbjct: 421 DILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPC 480

Query: 481 TLVTSCAVALWRRELGVFWTGSGFA 505
           TLVTSCAVALWRRELGVFWTGSGFA
Sbjct: 481 TLVTSCAVALWRRELGVFWTGSGFA 505


>gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]
          Length = 520

 Score =  489 bits (1260), Expect = e-138
 Identities = 239/503 (47%), Positives = 344/503 (68%), Gaps = 17/503 (3%)

Query: 5   VAAALARLLAAFLL--LAAQVACEYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLSKA 62
           ++ A A LL  FLL   AAQ A       ++  +G    KDYC+LYNP W  LP  L  A
Sbjct: 7   LSPAGAALLWGFLLQLTAAQEA-------ILHASGNGTTKDYCMLYNPYWTALPSTLENA 59

Query: 63  SFLQLRNWTASLLCSAADLPARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSRER 122
           + + L N T++ LC+ +D+P  G  ++  +V  G+C F EK R+AQ  GA  +L+V+   
Sbjct: 60  TSISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSV 119

Query: 123 LVPPGGNKTQYDEIGIPVALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMA 182
           L PP GN++++ ++ I +A +SYKD  D+    G  +   +Y+P  P  DY MV+IF++A
Sbjct: 120 LFPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIA 179

Query: 183 VGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVTPVMTCVFVVMCCSMLVLLYY 242
           V TVA+GGYW+G  +++        D    K+++E +  +P+   +FVV+CC M+VLLY+
Sbjct: 180 VFTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYF 239

Query: 243 FYDLLVYVVIGIFCLASATGLYSCLAPCVRRLPFGKCRIPNNSLPYFHKRPQARMLLLAL 302
           FY  LVYV+I IFC+ASA  LY+CLA  + ++P+G+C I         K  + R++ L+ 
Sbjct: 240 FYKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQCTIACRG-----KNMEVRLIFLSG 294

Query: 303 FCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLYDIFF 362
            C+AV+VVW VFRNED+WAW+LQD LGIAFCL ++KT++LP FK+C +LL +L LYD+FF
Sbjct: 295 LCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFF 354

Query: 363 VFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRL-NSSPLALCDRPFSLLGFGD 421
           VFITPF+TK+G SIMVE+A GP      EKLP+V++VP+L   S +++C  P S+LGFGD
Sbjct: 355 VFITPFITKNGESIMVELAAGP--FGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGD 412

Query: 422 ILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYLVPCT 481
           I+VPGLL+AYC RFD+Q  SS +Y+V+ T+AY +G+++TFV L LM++GQPALLYLVPCT
Sbjct: 413 IIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCT 472

Query: 482 LVTSCAVALWRRELGVFWTGSGF 504
           L+T+  VA  R+E+  FW G+ +
Sbjct: 473 LITASVVAWRRKEMKKFWKGNSY 495


>gi|38524591 intramembrane protease 5 [Homo sapiens]
          Length = 684

 Score =  485 bits (1248), Expect = e-137
 Identities = 267/531 (50%), Positives = 337/531 (63%), Gaps = 43/531 (8%)

Query: 12  LLAAFLLLAAQVAC-EYGMVHVVSQAGGPEGKDYCILYNPQWAHLPHDLSKASFLQLRNW 70
           L   FLLL + VA  +YG+ HVVS+      KDYCIL++  +  LP DL  A  L L + 
Sbjct: 8   LPVGFLLLISTVAGGKYGVAHVVSENWS---KDYCILFSSDYITLPRDLHHAPLLPLYDG 64

Query: 71  TASLLCSAADLP---------ARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSR- 120
           T +  C   D P          R       +V RGNC+F+ K  LAQG GA GLLIVSR 
Sbjct: 65  TKAPWCPGEDSPHQAQLRSPSQRPLRQTTAMVMRGNCSFHTKGWLAQGQGAHGLLIVSRV 124

Query: 121 ------ERLVPPGGNKTQYDEIGIPVALLSYKDMLDIF--TRFGRTVRAALYAPKEPVLD 172
                 +  + P   +    ++ IPVA+L Y DMLDI   TR    VR A+YAP EP++D
Sbjct: 125 SDQQCSDTTLAPQDPRQPLADLTIPVAMLHYADMLDILSHTRGEAVVRVAMYAPPEPIID 184

Query: 173 YNMVIIFIMAVGTVAIGGYWAGSRDVKKRYMKHKRDDG------------------PEKQ 214
           YNM++IFI+AVGTVA GGYWAG  +  +   +  R  G                   E  
Sbjct: 185 YNMLVIFILAVGTVAAGGYWAGLTEANRLQRRRARRGGGSGGHHQLQEAAAAEGAQKEDN 244

Query: 215 EDEAVDVTPVMTCVFVVMCCSMLVLLYYFYDLLVYVVIGIFCLASATGLYSCLAPCVRRL 274
           ED  VD TP MT V V + CS+++LLY+FYD  VYV IGIF L +  GLYSCL+P V  L
Sbjct: 245 EDIPVDFTPAMTGVVVTLSCSLMLLLYFFYDHFVYVTIGIFGLGAGIGLYSCLSPLVCHL 304

Query: 275 PFGKCRIPNNSLPYFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCL 334
              + + P +SL      P   +LLLA  C  V + W  +RNED+WAW+LQD LGI++CL
Sbjct: 305 SLRQYQRPPHSLWASLPLP---LLLLASLCATVIIFWVAYRNEDRWAWLLQDTLGISYCL 361

Query: 335 YMLKTIRLPTFKACTLLLLVLFLYDIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLP 394
           ++L  +RLPT K C+  LL L  +D+FFVF+TPF TK+G SIM +VA GP++S++ E+LP
Sbjct: 362 FVLHRVRLPTLKNCSSFLLALLAFDVFFVFVTPFFTKTGESIMAQVALGPAESSSHERLP 421

Query: 395 MVLKVPRLNSSPLALCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRVYFVACTIAYG 454
           MVLKVPRL  S L LC +PFS+LGFGDI+VPG LVAYC RFD+QV S ++YFVACT+AY 
Sbjct: 422 MVLKVPRLRVSALTLCSQPFSILGFGDIVVPGFLVAYCCRFDVQVCSRQIYFVACTVAYA 481

Query: 455 VGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRRELGVFWTGSGFA 505
           VGLLVTF+A+ LMQ GQPALLYLV  TL+TS AVA  R+EL +FWTG G A
Sbjct: 482 VGLLVTFMAMVLMQMGQPALLYLVSSTLLTSLAVAACRQELSLFWTGQGRA 532


>gi|33413418 signal peptide peptidase 3 [Homo sapiens]
          Length = 384

 Score =  109 bits (272), Expect = 7e-24
 Identities = 97/306 (31%), Positives = 145/306 (47%), Gaps = 59/306 (19%)

Query: 235 SMLVLLYYFYDLLVYVVIGIFCLASATGLYSCLAPCV---------RRLPFGKCRIPNNS 285
           S+LV+ ++F  + V   I    LA+    +  L  C           ++ FG C      
Sbjct: 83  SLLVMFFFFDSVQVVFTICTAVLATIAFAFLLLPMCQYLTRPCSPQNKISFGCCG----- 137

Query: 286 LPYFHKRPQARMLLLALFCVAVSVVWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTF 345
                 R  A  LL     V + ++W +  +     W+L DAL +  C+ M+  +RLP+ 
Sbjct: 138 ------RFTAAELLSFSLSVMLVLIWVLTGH-----WLLMDALAMGLCVAMIAFVRLPSL 186

Query: 346 KACTLLLLVLFLYDIFFVFITPFLTKSGSSIMVEVATGPSDS---ATREKL---PMVLK- 398
           K   LLL  L +YD+F+VF + ++    S++MV+VAT P+D+       KL   P V + 
Sbjct: 187 KVSCLLLSGLLIYDVFWVFFSAYI--FNSNVMVKVATQPADNPLDVLSRKLHLGPNVGRD 244

Query: 399 VPRLNSSPLAL-----CDRPFSLLGFGDILVPGLLVAYCHRFD----------------- 436
           VPRL S P  L         FS+LG GDI++PGLL+ +  R+D                 
Sbjct: 245 VPRL-SLPGKLVFPSSTGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQASGDSCGAPGPA 303

Query: 437 -IQVQSSRVYFVACT-IAYGVGLLVTFVALALMQRGQPALLYLVPCTLVTSCAVALWRRE 494
            I  +  +V +  CT I Y VGLL   VA  + +  QPALLYLVP TL+    +A  + +
Sbjct: 304 NISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTLLPLLTMAYLKGD 363

Query: 495 LGVFWT 500
           L   W+
Sbjct: 364 LRRMWS 369


>gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo
           sapiens]
          Length = 426

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 62/198 (31%), Positives = 100/198 (50%), Gaps = 24/198 (12%)

Query: 302 LFCVAVSV---VWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLY 358
           L C+ +S    VW + R      W+  +  G+AF L  ++ + L       +LL  LF+Y
Sbjct: 163 LVCLGLSSIVGVWYLLRKH----WIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIY 218

Query: 359 DIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLG 418
           D+F+VF        G+++MV VA          + P+ L  P+ +     L    F++LG
Sbjct: 219 DVFWVF--------GTNVMVTVAKS-------FEAPIKLVFPQ-DLLEKGLEANNFAMLG 262

Query: 419 FGDILVPGLLVAYCHRFDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYL 477
            GD+++PG+ +A   RFDI ++ ++  YF     AY  GL +T   + + +  QPALLYL
Sbjct: 263 LGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYL 322

Query: 478 VPCTLVTSCAVALWRREL 495
           VP  +     VAL + E+
Sbjct: 323 VPACIGFPVLVALAKGEV 340


>gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo
           sapiens]
          Length = 394

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 62/198 (31%), Positives = 100/198 (50%), Gaps = 24/198 (12%)

Query: 302 LFCVAVSV---VWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLY 358
           L C+ +S    VW + R      W+  +  G+AF L  ++ + L       +LL  LF+Y
Sbjct: 163 LVCLGLSSIVGVWYLLRKH----WIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIY 218

Query: 359 DIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLG 418
           D+F+VF        G+++MV VA          + P+ L  P+ +     L    F++LG
Sbjct: 219 DVFWVF--------GTNVMVTVAKS-------FEAPIKLVFPQ-DLLEKGLEANNFAMLG 262

Query: 419 FGDILVPGLLVAYCHRFDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYL 477
            GD+++PG+ +A   RFDI ++ ++  YF     AY  GL +T   + + +  QPALLYL
Sbjct: 263 LGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYL 322

Query: 478 VPCTLVTSCAVALWRREL 495
           VP  +     VAL + E+
Sbjct: 323 VPACIGFPVLVALAKGEV 340


>gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo
           sapiens]
          Length = 377

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 62/198 (31%), Positives = 100/198 (50%), Gaps = 24/198 (12%)

Query: 302 LFCVAVSV---VWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLY 358
           L C+ +S    VW + R      W+  +  G+AF L  ++ + L       +LL  LF+Y
Sbjct: 163 LVCLGLSSIVGVWYLLRKH----WIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIY 218

Query: 359 DIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLG 418
           D+F+VF        G+++MV VA          + P+ L  P+ +     L    F++LG
Sbjct: 219 DVFWVF--------GTNVMVTVAKS-------FEAPIKLVFPQ-DLLEKGLEANNFAMLG 262

Query: 419 FGDILVPGLLVAYCHRFDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYL 477
            GD+++PG+ +A   RFDI ++ ++  YF     AY  GL +T   + + +  QPALLYL
Sbjct: 263 LGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYL 322

Query: 478 VPCTLVTSCAVALWRREL 495
           VP  +     VAL + E+
Sbjct: 323 VPACIGFPVLVALAKGEV 340


>gi|21040269 ring finger protein 133 [Homo sapiens]
          Length = 376

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 16/41 (39%), Positives = 26/41 (63%), Gaps = 4/41 (9%)

Query: 90  IPLVARGNCTFYEKVRLAQGSGARGLLIVSRERLVPPGGNK 130
           + L+ RG CTF +K+++A   GA G++I +    VP  GN+
Sbjct: 102 LALIERGGCTFTQKIKVATEKGASGVIIYN----VPGTGNQ 138


>gi|29789407 ring finger protein 149 [Homo sapiens]
          Length = 400

 Score = 33.9 bits (76), Expect = 0.36
 Identities = 16/39 (41%), Positives = 24/39 (61%)

Query: 84  RGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIVSRER 122
           RG +  + LVARG CTF +KV +A    A  +++ + ER
Sbjct: 104 RGAAPWVALVARGGCTFKDKVLVAARRNASAVVLYNEER 142


>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
           [Homo sapiens]
          Length = 932

 Score = 33.9 bits (76), Expect = 0.36
 Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 8/67 (11%)

Query: 89  QIPLVARGNCTFYEKVRLAQGSGARGLLIVSRER--------LVPPGGNKTQYDEIGIPV 140
           +I L+ RG C F EK R  Q +GA G +++            L    G+    D+I IP+
Sbjct: 705 KIALIQRGQCMFAEKARNIQNAGAIGGIVIDDNEGSSSDTAPLFQMAGDGKDTDDIKIPM 764

Query: 141 ALLSYKD 147
             L  K+
Sbjct: 765 LFLFSKE 771


>gi|14150090 chromosome 2 open reading frame 7 [Homo sapiens]
          Length = 188

 Score = 32.7 bits (73), Expect = 0.81
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 88  NQIPLVARGNCTFYEKVRLAQGSGARGLLI 117
           +QI LV RG C+F  K R+ Q  G R ++I
Sbjct: 85  DQIALVERGGCSFLSKTRVVQEHGGRAVII 114


>gi|37588871 ring finger protein 128 isoform 2 [Homo sapiens]
          Length = 402

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 4/42 (9%)

Query: 90  IPLVARGNCTFYEKVRLAQGSGARGLLIVSRERLVPPGGNKT 131
           I L+ RGNCTF EK++ A    A  ++I +     P  GN+T
Sbjct: 92  IALIERGNCTFSEKIQTAGRRNADAVVIYN----APETGNQT 129


>gi|157694503 solute carrier family 14 (urea transporter), member 2
           [Homo sapiens]
          Length = 920

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 29/121 (23%), Positives = 53/121 (43%), Gaps = 13/121 (10%)

Query: 298 LLLALFCVAVSVVWGVFRNEDQWAW---VLQDALGIAFCLYMLKTIRLPTFKACTLLLLV 354
           LL+A+F   +   W +       A    VL  AL   F  + L    LP   A TL L  
Sbjct: 191 LLMAVFSEKLDYYWWLLFPVTFTAMSCPVLSSALNSIFSKWDLPVFTLPFNIAVTLYLAA 250

Query: 355 LFLYDIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPF 414
              Y++FF           ++++  V++ P+ + T  ++P++L+   +    +  CD P+
Sbjct: 251 TGHYNLFFP----------TTLVEPVSSVPNITWTEMEMPLLLQAIPVGVGQVYGCDNPW 300

Query: 415 S 415
           +
Sbjct: 301 T 301



 Score = 29.6 bits (65), Expect = 6.8
 Identities = 25/125 (20%), Positives = 51/125 (40%), Gaps = 24/125 (19%)

Query: 305 VAVSVVWGVFRNEDQWAW--------------VLQDALGIAFCLYMLKTIRLPTFKACTL 350
           V V ++  VF ++  + W              +L  ALG  F  + L    LP     TL
Sbjct: 649 VLVGLLMAVFSDKGDYYWWLLLPVIIMSMSCPILSSALGTIFSKWDLPVFTLPFNITVTL 708

Query: 351 LLLVLFLYDIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALC 410
            L     Y++FF           ++++   +  P+ + +  ++P++L+   +    +  C
Sbjct: 709 YLAATGHYNLFF----------PTTLLQPASAMPNITWSEVQVPLLLRAIPVGIGQVYGC 758

Query: 411 DRPFS 415
           D P++
Sbjct: 759 DNPWT 763


>gi|37675277 ring finger protein 148 [Homo sapiens]
          Length = 305

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 12/28 (42%), Positives = 18/28 (64%)

Query: 90  IPLVARGNCTFYEKVRLAQGSGARGLLI 117
           + L+ RG CTF  K+ +A   GA G++I
Sbjct: 102 LALIERGGCTFTHKINVAAEKGANGVII 129


>gi|29788758 ring finger protein 130 [Homo sapiens]
          Length = 419

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 32/138 (23%), Positives = 54/138 (39%), Gaps = 13/138 (9%)

Query: 90  IPLVARGNCTFYEKVRLAQGSGARGLLIVSRE------RLVPPGGNKTQYDEIGIPVALL 143
           I L+ RGNCTF EK+  A    A  ++I + +       +  PG      D I + +  L
Sbjct: 105 IALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPGTG----DIIAVMITEL 160

Query: 144 SYKDMLDIFTR---FGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIGGYWAGSRDVKK 200
             KD+L    +      T+      P +     ++V + I  +  + I   W     ++K
Sbjct: 161 RGKDILSYLEKNISVQMTIAVGTRMPPKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQK 220

Query: 201 RYMKHKRDDGPEKQEDEA 218
               + RD    +  D A
Sbjct: 221 IRYTNARDRNQRRLGDAA 238


>gi|58331204 ring finger protein 150 [Homo sapiens]
          Length = 438

 Score = 30.8 bits (68), Expect = 3.1
 Identities = 34/138 (24%), Positives = 57/138 (41%), Gaps = 20/138 (14%)

Query: 82  PARGFSNQIPLVARGNCTFYEKVRLAQGSGARGLLIV-----SRERLVPPGGNKTQYDEI 136
           P RG  N I L+ +GNCT+ +K+R A    A  ++I      + E +  P         I
Sbjct: 111 PTRG-KNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPHAGVEDIVAI 169

Query: 137 GIP-------VALLSYKDMLDIFTRFGRTVRAALYAPKEPVLDYNMVIIFIMAVGTVAIG 189
            IP       V+LL     + ++   G T     Y  +  V+  ++  I +M +    + 
Sbjct: 170 MIPEPKGKEIVSLLERNITVTMYITIG-TRNLQKYVSRTSVVFVSISFIVLMIISLAWLV 228

Query: 190 GY------WAGSRDVKKR 201
            Y      +A +RD  +R
Sbjct: 229 FYYIQRFRYANARDRNQR 246


>gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens]
          Length = 305

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 30/108 (27%)

Query: 176 VIIFIMAVGTVAIGGYWAGSRDVKKRYMKHKRDDGPEKQEDEAVDVT--PVMTCVFVVMC 233
           ++ ++M++  +A+  +        + Y+ +      E + +EAV +T  PV+  V + +C
Sbjct: 19  LLFWLMSISVLAVSAWM-------RDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVC 71

Query: 234 C----------------SMLVLLYYFYDLLVYVVIGIFCLASATGLYS 265
           C                ++L+L +YF  LLV     IFC+  A G+++
Sbjct: 72  CFLIIVGMLGYCGTVKRNLLLLAWYFGSLLV-----IFCVELACGVWT 114


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.142    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,958,148
Number of Sequences: 37866
Number of extensions: 815685
Number of successful extensions: 2258
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2221
Number of HSP's gapped (non-prelim): 22
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.