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Search of human proteins with 116642865
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]
(802 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens] 1693 0.0
gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens] 1686 0.0
gi|19718759 myoferlin isoform b [Homo sapiens] 718 0.0
gi|7305053 myoferlin isoform a [Homo sapiens] 718 0.0
gi|195976821 dysferlin isoform 2 [Homo sapiens] 714 0.0
gi|4503431 dysferlin isoform 8 [Homo sapiens] 714 0.0
gi|195976777 dysferlin isoform 3 [Homo sapiens] 714 0.0
gi|195976775 dysferlin isoform 4 [Homo sapiens] 714 0.0
gi|195976766 dysferlin isoform 7 [Homo sapiens] 714 0.0
gi|195976762 dysferlin isoform 13 [Homo sapiens] 714 0.0
gi|195976760 dysferlin isoform 12 [Homo sapiens] 714 0.0
gi|195976754 dysferlin isoform 9 [Homo sapiens] 714 0.0
gi|195976779 dysferlin isoform 1 [Homo sapiens] 711 0.0
gi|195976773 dysferlin isoform 5 [Homo sapiens] 711 0.0
gi|195976769 dysferlin isoform 6 [Homo sapiens] 711 0.0
gi|195976764 dysferlin isoform 14 [Homo sapiens] 711 0.0
gi|195976758 dysferlin isoform 11 [Homo sapiens] 711 0.0
gi|195976756 dysferlin isoform 10 [Homo sapiens] 711 0.0
gi|35493853 otoferlin isoform c [Homo sapiens] 429 e-120
gi|35493868 otoferlin isoform b [Homo sapiens] 429 e-120
gi|34740331 otoferlin isoform a [Homo sapiens] 429 e-120
gi|119120884 fer-1-like 6 [Homo sapiens] 426 e-119
gi|35493860 otoferlin isoform d [Homo sapiens] 421 e-117
gi|28376627 synaptotagmin IX [Homo sapiens] 49 2e-05
gi|238550198 synaptotagmin III [Homo sapiens] 49 2e-05
gi|238550196 synaptotagmin III [Homo sapiens] 49 2e-05
gi|14150054 synaptotagmin III [Homo sapiens] 49 2e-05
gi|103472031 family with sequence similarity 62 (C2 domain conta... 45 3e-04
gi|209447073 synaptotagmin I [Homo sapiens] 44 5e-04
gi|5032139 synaptotagmin I [Homo sapiens] 44 5e-04
>gi|116642865 fer-1-like 5 isoform 1 [Homo sapiens]
Length = 802
Score = 1693 bits (4385), Expect = 0.0
Identities = 802/802 (100%), Positives = 802/802 (100%)
Query: 1 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60
MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV
Sbjct: 1 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60
Query: 61 DNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPTLSEKKHQDFLGYLYRKFWFKSS 120
DNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPTLSEKKHQDFLGYLYRKFWFKSS
Sbjct: 61 DNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPTLSEKKHQDFLGYLYRKFWFKSS 120
Query: 121 KAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFK 180
KAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFK
Sbjct: 121 KAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFK 180
Query: 181 LYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRA 240
LYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRA
Sbjct: 181 LYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRA 240
Query: 241 INLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQL 300
INLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQL
Sbjct: 241 INLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQL 300
Query: 301 YDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAK 360
YDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAK
Sbjct: 301 YDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAK 360
Query: 361 RKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHV 420
RKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHV
Sbjct: 361 RKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHV 420
Query: 421 ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWKTANVDL 480
ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWKTANVDL
Sbjct: 421 ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWKTANVDL 480
Query: 481 VDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCV 540
VDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCV
Sbjct: 481 VDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCV 540
Query: 541 QSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIR 600
QSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIR
Sbjct: 541 QSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIR 600
Query: 601 MMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIK 660
MMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIK
Sbjct: 601 MMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALIK 660
Query: 661 PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML 720
PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML
Sbjct: 661 PAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALML 720
Query: 721 FNFIYSAPHYLAMSWIKPQLQLYPPIKIFNIINSLNTSNASSSILPTQDPNLKPTIDHEW 780
FNFIYSAPHYLAMSWIKPQLQLYPPIKIFNIINSLNTSNASSSILPTQDPNLKPTIDHEW
Sbjct: 721 FNFIYSAPHYLAMSWIKPQLQLYPPIKIFNIINSLNTSNASSSILPTQDPNLKPTIDHEW 780
Query: 781 KLHPGPTNHLSDIFPELPAPGD 802
KLHPGPTNHLSDIFPELPAPGD
Sbjct: 781 KLHPGPTNHLSDIFPELPAPGD 802
>gi|164607133 fer-1-like 5 isoform 2 [Homo sapiens]
Length = 2093
Score = 1686 bits (4365), Expect = 0.0
Identities = 802/811 (98%), Positives = 802/811 (98%), Gaps = 9/811 (1%)
Query: 1 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60
MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV
Sbjct: 1283 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 1342
Query: 61 DNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPTLSEKKHQDFLGYLYRKFWFKSS 120
DNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPTLSEKKHQDFLGYLYRKFWFKSS
Sbjct: 1343 DNWAFGQQTVTGQANIDFLQPYFCDPWAQDYMHPKLPTLSEKKHQDFLGYLYRKFWFKSS 1402
Query: 121 KAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFK 180
KAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFK
Sbjct: 1403 KAEDEYEHEVDWWSKLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFK 1462
Query: 181 LYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRA 240
LYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRA
Sbjct: 1463 LYQEQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRA 1522
Query: 241 INLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQL 300
INLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQL
Sbjct: 1523 INLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQL 1582
Query: 301 YDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAK 360
YDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAK
Sbjct: 1583 YDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAK 1642
Query: 361 RKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHV 420
RKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHV
Sbjct: 1643 RKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQGLVPEHV 1702
Query: 421 ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPK---------RYELRCI 471
ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPK RYELRCI
Sbjct: 1703 ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRKASEHSGHRYELRCI 1762
Query: 472 IWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMD 531
IWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMD
Sbjct: 1763 IWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMD 1822
Query: 532 YLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPA 591
YLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPA
Sbjct: 1823 YLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPA 1882
Query: 592 RHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEI 651
RHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEI
Sbjct: 1883 RHAKQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEI 1942
Query: 652 LSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFM 711
LSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFM
Sbjct: 1943 LSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFM 2002
Query: 712 VISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIFNIINSLNTSNASSSILPTQDPN 771
VISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIFNIINSLNTSNASSSILPTQDPN
Sbjct: 2003 VISIIALMLFNFIYSAPHYLAMSWIKPQLQLYPPIKIFNIINSLNTSNASSSILPTQDPN 2062
Query: 772 LKPTIDHEWKLHPGPTNHLSDIFPELPAPGD 802
LKPTIDHEWKLHPGPTNHLSDIFPELPAPGD
Sbjct: 2063 LKPTIDHEWKLHPGPTNHLSDIFPELPAPGD 2093
>gi|19718759 myoferlin isoform b [Homo sapiens]
Length = 2048
Score = 718 bits (1853), Expect = 0.0
Identities = 357/746 (47%), Positives = 493/746 (66%), Gaps = 11/746 (1%)
Query: 1 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60
M +SP L+VE G E + + I++ + PNFP S VL + V +P EE Y PLV+KV+
Sbjct: 1308 MASITSPSLVVECGGERVESVVIKNLKKTPNFPSS--VLFMKVFLPKEELYMPPLVIKVI 1365
Query: 61 DNWAFGQQTVTGQANIDFLQPYFCDPWA-QDYMHPKLPT--LSEKKHQDFLGYLYRKFWF 117
D+ FG++ V GQ I+ L + CDP+A ++ + P+L LS +D + +
Sbjct: 1366 DHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQLKASLLSAPPCRDIVIEMEDTKPL 1425
Query: 118 KSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFC 176
+SK ++ E VDWWSK + ++ EH+ +Y K Y LK+Y CELE V F+GL DF
Sbjct: 1426 LASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFS 1485
Query: 177 QTFKLYQ--EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVR 234
TFKLY+ D VVGEFKG FRIYP P++P P PP QF P+ PQ C VR
Sbjct: 1486 DTFKLYRGKSDENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPD--SVPQECTVR 1543
Query: 235 VYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEK 294
+Y+VR + LQPQD NGLCDPY+ + LGK + +RD Y PNTL+P+FG M+EL+C +P EK
Sbjct: 1544 IYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEK 1603
Query: 295 DLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYL 354
DL+I +YD+D F+ D+K+G T+IDLENR LS FG+HCG+ + YC SG WRDQ+ P+ L
Sbjct: 1604 DLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQL 1663
Query: 355 LERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQG 414
L+ A+ KG P P+ S + + Y G+ + L FE LG +ERLAL++L TQG
Sbjct: 1664 LQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQG 1723
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVETRTL+S QP I QGK+QMWVD+FPK LGPPGP NI PRK K+Y LR IIW
Sbjct: 1724 LVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWN 1783
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L + +++ E+ SDIY+KGW+ G E++ QKTD+HY SL GE +FNWRF+F DYL
Sbjct: 1784 TKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLP 1843
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C+ ++K++ WS+D T + P RLIIQ+WDND FS DD+LG LELDL +PA+
Sbjct: 1844 AEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSP 1903
Query: 595 KQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSE 654
++C + M+ D K ++ K SLF++K++ GWWPC G ++GKV+M+LEIL+E
Sbjct: 1904 EKCRLDMI-PDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNE 1962
Query: 655 KEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVIS 714
KEA +PAG+G+ EPN P L P R TSF W +P + +I W+R+++ +I + +
Sbjct: 1963 KEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLL 2022
Query: 715 IIALMLFNFIYSAPHYLAMSWIKPQL 740
I+ L + +YS P+YL+M +KP +
Sbjct: 2023 ILLLFVAVLLYSLPNYLSMKIVKPNV 2048
Score = 33.1 bits (74), Expect = 1.0
Identities = 54/213 (25%), Positives = 86/213 (40%), Gaps = 24/213 (11%)
Query: 225 EDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKL-GKTELGNRDMYQPNTLDPIFGMM 283
ED PQ V+ I D L DP+V + GK N + + N +P + +
Sbjct: 368 EDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTN--IIEKNA-NPEWNQV 424
Query: 284 FELTCNIP-LEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGP 342
L P + + +++ +YD+D + +D +GTT + L SG ++ P
Sbjct: 425 VNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEVNTGETEVGFVP 484
Query: 343 FRWRDQMPPSYLLERYAKRK--GLPPP---LFSPEEDAVFYNGK-KFKLQSFEPKTPTVH 396
P YL + R+ G P P L + + + V Y G+ +L +F KTP
Sbjct: 485 -----TFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEKTPPDK 539
Query: 397 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHS 429
L P + + LV E + R YS S
Sbjct: 540 KLEP--------ISNDDLLVVEKYQRRRKYSLS 564
>gi|7305053 myoferlin isoform a [Homo sapiens]
Length = 2061
Score = 718 bits (1853), Expect = 0.0
Identities = 357/746 (47%), Positives = 493/746 (66%), Gaps = 11/746 (1%)
Query: 1 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60
M +SP L+VE G E + + I++ + PNFP S VL + V +P EE Y PLV+KV+
Sbjct: 1321 MASITSPSLVVECGGERVESVVIKNLKKTPNFPSS--VLFMKVFLPKEELYMPPLVIKVI 1378
Query: 61 DNWAFGQQTVTGQANIDFLQPYFCDPWA-QDYMHPKLPT--LSEKKHQDFLGYLYRKFWF 117
D+ FG++ V GQ I+ L + CDP+A ++ + P+L LS +D + +
Sbjct: 1379 DHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQLKASLLSAPPCRDIVIEMEDTKPL 1438
Query: 118 KSSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFC 176
+SK ++ E VDWWSK + ++ EH+ +Y K Y LK+Y CELE V F+GL DF
Sbjct: 1439 LASKLTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFS 1498
Query: 177 QTFKLYQ--EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVR 234
TFKLY+ D VVGEFKG FRIYP P++P P PP QF P+ PQ C VR
Sbjct: 1499 DTFKLYRGKSDENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPD--SVPQECTVR 1556
Query: 235 VYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEK 294
+Y+VR + LQPQD NGLCDPY+ + LGK + +RD Y PNTL+P+FG M+EL+C +P EK
Sbjct: 1557 IYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEK 1616
Query: 295 DLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYL 354
DL+I +YD+D F+ D+K+G T+IDLENR LS FG+HCG+ + YC SG WRDQ+ P+ L
Sbjct: 1617 DLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQL 1676
Query: 355 LERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQG 414
L+ A+ KG P P+ S + + Y G+ + L FE LG +ERLAL++L TQG
Sbjct: 1677 LQNVARFKGFPQPILSEDGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQG 1736
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVETRTL+S QP I QGK+QMWVD+FPK LGPPGP NI PRK K+Y LR IIW
Sbjct: 1737 LVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWN 1796
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L + +++ E+ SDIY+KGW+ G E++ QKTD+HY SL GE +FNWRF+F DYL
Sbjct: 1797 TKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLP 1856
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C+ ++K++ WS+D T + P RLIIQ+WDND FS DD+LG LELDL +PA+
Sbjct: 1857 AEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSP 1916
Query: 595 KQCSIRMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSE 654
++C + M+ D K ++ K SLF++K++ GWWPC G ++GKV+M+LEIL+E
Sbjct: 1917 EKCRLDMI-PDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGARVMAGKVEMTLEILNE 1975
Query: 655 KEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVIS 714
KEA +PAG+G+ EPN P L P R TSF W +P + +I W+R+++ +I + +
Sbjct: 1976 KEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLL 2035
Query: 715 IIALMLFNFIYSAPHYLAMSWIKPQL 740
I+ L + +YS P+YL+M +KP +
Sbjct: 2036 ILLLFVAVLLYSLPNYLSMKIVKPNV 2061
Score = 30.4 bits (67), Expect = 6.8
Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 5/104 (4%)
Query: 225 EDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKL-GKTELGNRDMYQPNTLDPIFGMM 283
ED PQ V+ I D L DP+V + GK N + + N +P + +
Sbjct: 368 EDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTN--IIEKNA-NPEWNQV 424
Query: 284 FELTCNIP-LEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSG 326
L P + + +++ +YD+D + +D +GTT + L SG
Sbjct: 425 VNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASG 468
>gi|195976821 dysferlin isoform 2 [Homo sapiens]
Length = 2081
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1354 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1411
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 1412 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1465
Query: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 1466 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1525
Query: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 1526 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1583
Query: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 1584 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1643
Query: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 1644 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1703
Query: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 1704 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1760
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 1761 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1820
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 1821 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1880
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 1881 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1940
Query: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 1941 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 1993
Query: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 1994 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2053
Query: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 2054 LFILLLFLAIFIYAFPNYAAMKLVKP 2079
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1155 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1212
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1213 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1245
>gi|4503431 dysferlin isoform 8 [Homo sapiens]
Length = 2080
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1353 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1410
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 1411 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1464
Query: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 1465 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1524
Query: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 1525 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1582
Query: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 1583 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1642
Query: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 1643 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1702
Query: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 1703 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1759
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 1760 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1819
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 1820 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1879
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 1880 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1939
Query: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 1940 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 1992
Query: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 1993 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2052
Query: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 2053 LFILLLFLAIFIYAFPNYAAMKLVKP 2078
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1154 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1211
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1212 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1244
>gi|195976777 dysferlin isoform 3 [Homo sapiens]
Length = 2067
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1340 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1397
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 1398 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1451
Query: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 1452 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1511
Query: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 1512 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1569
Query: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 1570 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1629
Query: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 1630 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1689
Query: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 1690 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1746
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 1747 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1806
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 1807 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1866
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 1867 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1926
Query: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 1927 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 1979
Query: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 1980 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2039
Query: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 2040 LFILLLFLAIFIYAFPNYAAMKLVKP 2065
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1198
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1199 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1231
>gi|195976775 dysferlin isoform 4 [Homo sapiens]
Length = 2098
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1371 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1428
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 1429 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1482
Query: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 1483 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1542
Query: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 1543 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1600
Query: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 1601 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1660
Query: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 1661 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1720
Query: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 1721 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1777
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 1778 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1837
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 1838 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1897
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 1898 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1957
Query: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 1958 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2010
Query: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 2011 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2070
Query: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 2071 LFILLLFLAIFIYAFPNYAAMKLVKP 2096
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1172 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1229
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1230 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1262
>gi|195976766 dysferlin isoform 7 [Homo sapiens]
Length = 2112
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1385 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1442
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 1443 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1496
Query: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 1497 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1556
Query: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 1557 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1614
Query: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 1615 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1674
Query: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 1675 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1734
Query: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 1735 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1791
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 1792 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1851
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 1852 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1911
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 1912 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1971
Query: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 1972 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2024
Query: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 2025 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2084
Query: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 2085 LFILLLFLAIFIYAFPNYAAMKLVKP 2110
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1186 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1243
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1244 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1276
>gi|195976762 dysferlin isoform 13 [Homo sapiens]
Length = 2097
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1370 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1427
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 1428 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1481
Query: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 1482 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1541
Query: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 1542 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1599
Query: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 1600 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1659
Query: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 1660 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1719
Query: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 1720 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1776
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 1777 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1836
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 1837 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1896
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 1897 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1956
Query: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 1957 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2009
Query: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 2010 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2069
Query: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 2070 LFILLLFLAIFIYAFPNYAAMKLVKP 2095
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1171 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1228
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1229 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1261
>gi|195976760 dysferlin isoform 12 [Homo sapiens]
Length = 2111
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1384 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1441
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 1442 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1495
Query: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 1496 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1555
Query: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 1556 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1613
Query: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 1614 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1673
Query: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 1674 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1733
Query: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 1734 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1790
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 1791 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1850
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 1851 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1910
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 1911 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1970
Query: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 1971 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 2023
Query: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 2024 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2083
Query: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 2084 LFILLLFLAIFIYAFPNYAAMKLVKP 2109
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1185 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1242
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1243 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1275
>gi|195976754 dysferlin isoform 9 [Homo sapiens]
Length = 2066
Score = 714 bits (1842), Expect = 0.0
Identities = 366/746 (49%), Positives = 494/746 (66%), Gaps = 32/746 (4%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1339 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1396
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK-----LPTLSEKKHQDFLGYLYRKFWFKS 119
FG++ V GQ I L+ + CDP++ + P+ + LS +D L + K
Sbjct: 1397 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPG--EDVLIDIDDK----E 1450
Query: 120 SKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYECELEAVPAFQGLQDFCQT 178
+ E +DWWSK F + E + Y KD+ TLKVY+ +LE V AF+GL DFC T
Sbjct: 1451 PLIPIQEEEFIDWWSKFFASIGEREKCGSYLEKDFDTLKVYDTQLENVEAFEGLSDFCNT 1510
Query: 179 FKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRV 235
FKLY+ ++ D V+GEFKGLF+IYP PE+P P PP QF + PQ CLVR+
Sbjct: 1511 FKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQFHQLAAQG--PQECLVRI 1568
Query: 236 YMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKD 295
Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+P+FG MFELTC +PLEKD
Sbjct: 1569 YIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLEPVFGKMFELTCTLPLEKD 1628
Query: 296 LEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLL 355
L+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++YC SGP +WRDQ+ PS LL
Sbjct: 1629 LKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTYCVSGPNQWRDQLRPSQLL 1688
Query: 356 ERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVHGLGPKKERLALYLLHTQG 414
+ ++ + P++ D V + K++ ++ E + P H LGP +ERLAL++L QG
Sbjct: 1689 HLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH-LGPVEERLALHVLQQQG 1745
Query: 415 LVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWK 474
LVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP NI PR+ +R+ LRCIIW
Sbjct: 1746 LVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPFNITPRRARRFFLRCIIWN 1805
Query: 475 TANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLA 534
T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL GE +FNWRFIF DYL
Sbjct: 1806 TRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSLGGEGNFNWRFIFPFDYLP 1865
Query: 535 AERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHA 594
AE+ C ++KD W LD T K PAR++ Q+WDND FS DDFLG L+LDL+ MP PA+ A
Sbjct: 1866 AEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDFLGSLQLDLNRMPKPAKTA 1925
Query: 595 KQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEIL 652
K+CS+ +D P+W SLF++KTV GWWPC +G K L+GK++M+LEI+
Sbjct: 1926 KKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAEEGEKKILAGKLEMTLEIV 1978
Query: 653 SEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMV 712
+E E +PAG+G+ EPN P L P R +TSF W SP + +I W+R+R+ +I F++
Sbjct: 1979 AESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKTMKFILWRRFRWAIILFII 2038
Query: 713 ISIIALMLFNFIYSAPHYLAMSWIKP 738
+ I+ L L FIY+ P+Y AM +KP
Sbjct: 2039 LFILLLFLAIFIYAFPNYAAMKLVKP 2064
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1197
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1198 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1230
>gi|195976779 dysferlin isoform 1 [Homo sapiens]
Length = 2119
Score = 711 bits (1836), Expect = 0.0
Identities = 369/764 (48%), Positives = 498/764 (65%), Gaps = 47/764 (6%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1371 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1428
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---------------LPTLSEKKH----- 104
FG++ V GQ I L+ + CDP++ + P+ L + +K+
Sbjct: 1429 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ 1488
Query: 105 -QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 160
D L L SS E+E+ +DWWSK F + E + Y KD+ TLKVY+
Sbjct: 1489 LADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1545
Query: 161 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 217
+LE V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP Q
Sbjct: 1546 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1605
Query: 218 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 277
F + PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+
Sbjct: 1606 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1663
Query: 278 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 337
P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 1664 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1723
Query: 338 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 396
C SGP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H
Sbjct: 1724 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1781
Query: 397 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 456
LGP +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP
Sbjct: 1782 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1840
Query: 457 NINPRKPKRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSL 516
NI PR+ +R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL
Sbjct: 1841 NITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSL 1900
Query: 517 TGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDF 576
GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND FS DDF
Sbjct: 1901 GGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDF 1960
Query: 577 LGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL 634
LG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GWWPC
Sbjct: 1961 LGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAE 2013
Query: 635 DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQN 694
+G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W SP +
Sbjct: 2014 EGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKT 2073
Query: 695 FCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 738
+I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP
Sbjct: 2074 MKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2117
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1172 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1229
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1230 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1262
>gi|195976773 dysferlin isoform 5 [Homo sapiens]
Length = 2088
Score = 711 bits (1836), Expect = 0.0
Identities = 369/764 (48%), Positives = 498/764 (65%), Gaps = 47/764 (6%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1340 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1397
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---------------LPTLSEKKH----- 104
FG++ V GQ I L+ + CDP++ + P+ L + +K+
Sbjct: 1398 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ 1457
Query: 105 -QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 160
D L L SS E+E+ +DWWSK F + E + Y KD+ TLKVY+
Sbjct: 1458 LADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1514
Query: 161 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 217
+LE V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP Q
Sbjct: 1515 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1574
Query: 218 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 277
F + PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+
Sbjct: 1575 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1632
Query: 278 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 337
P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 1633 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1692
Query: 338 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 396
C SGP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H
Sbjct: 1693 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1750
Query: 397 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 456
LGP +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP
Sbjct: 1751 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1809
Query: 457 NINPRKPKRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSL 516
NI PR+ +R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL
Sbjct: 1810 NITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSL 1869
Query: 517 TGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDF 576
GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND FS DDF
Sbjct: 1870 GGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDF 1929
Query: 577 LGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL 634
LG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GWWPC
Sbjct: 1930 LGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAE 1982
Query: 635 DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQN 694
+G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W SP +
Sbjct: 1983 EGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKT 2042
Query: 695 FCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 738
+I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP
Sbjct: 2043 MKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2086
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1141 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1198
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1199 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1231
>gi|195976769 dysferlin isoform 6 [Homo sapiens]
Length = 2102
Score = 711 bits (1836), Expect = 0.0
Identities = 369/764 (48%), Positives = 498/764 (65%), Gaps = 47/764 (6%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1354 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1411
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---------------LPTLSEKKH----- 104
FG++ V GQ I L+ + CDP++ + P+ L + +K+
Sbjct: 1412 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ 1471
Query: 105 -QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 160
D L L SS E+E+ +DWWSK F + E + Y KD+ TLKVY+
Sbjct: 1472 LADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1528
Query: 161 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 217
+LE V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP Q
Sbjct: 1529 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1588
Query: 218 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 277
F + PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+
Sbjct: 1589 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1646
Query: 278 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 337
P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 1647 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1706
Query: 338 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 396
C SGP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H
Sbjct: 1707 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1764
Query: 397 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 456
LGP +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP
Sbjct: 1765 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1823
Query: 457 NINPRKPKRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSL 516
NI PR+ +R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL
Sbjct: 1824 NITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSL 1883
Query: 517 TGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDF 576
GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND FS DDF
Sbjct: 1884 GGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDF 1943
Query: 577 LGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL 634
LG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GWWPC
Sbjct: 1944 LGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAE 1996
Query: 635 DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQN 694
+G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W SP +
Sbjct: 1997 EGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKT 2056
Query: 695 FCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 738
+I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP
Sbjct: 2057 MKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2100
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1155 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1212
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1213 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1245
>gi|195976764 dysferlin isoform 14 [Homo sapiens]
Length = 2118
Score = 711 bits (1836), Expect = 0.0
Identities = 369/764 (48%), Positives = 498/764 (65%), Gaps = 47/764 (6%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1370 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1427
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---------------LPTLSEKKH----- 104
FG++ V GQ I L+ + CDP++ + P+ L + +K+
Sbjct: 1428 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ 1487
Query: 105 -QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 160
D L L SS E+E+ +DWWSK F + E + Y KD+ TLKVY+
Sbjct: 1488 LADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1544
Query: 161 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 217
+LE V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP Q
Sbjct: 1545 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1604
Query: 218 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 277
F + PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+
Sbjct: 1605 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1662
Query: 278 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 337
P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 1663 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1722
Query: 338 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 396
C SGP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H
Sbjct: 1723 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1780
Query: 397 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 456
LGP +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP
Sbjct: 1781 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1839
Query: 457 NINPRKPKRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSL 516
NI PR+ +R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL
Sbjct: 1840 NITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSL 1899
Query: 517 TGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDF 576
GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND FS DDF
Sbjct: 1900 GGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDF 1959
Query: 577 LGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL 634
LG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GWWPC
Sbjct: 1960 LGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAE 2012
Query: 635 DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQN 694
+G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W SP +
Sbjct: 2013 EGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKT 2072
Query: 695 FCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 738
+I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP
Sbjct: 2073 MKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2116
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1171 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1228
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1229 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1261
>gi|195976758 dysferlin isoform 11 [Homo sapiens]
Length = 2101
Score = 711 bits (1836), Expect = 0.0
Identities = 369/764 (48%), Positives = 498/764 (65%), Gaps = 47/764 (6%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1353 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1410
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---------------LPTLSEKKH----- 104
FG++ V GQ I L+ + CDP++ + P+ L + +K+
Sbjct: 1411 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ 1470
Query: 105 -QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 160
D L L SS E+E+ +DWWSK F + E + Y KD+ TLKVY+
Sbjct: 1471 LADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1527
Query: 161 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 217
+LE V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP Q
Sbjct: 1528 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1587
Query: 218 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 277
F + PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+
Sbjct: 1588 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1645
Query: 278 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 337
P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 1646 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1705
Query: 338 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 396
C SGP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H
Sbjct: 1706 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1763
Query: 397 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 456
LGP +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP
Sbjct: 1764 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1822
Query: 457 NINPRKPKRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSL 516
NI PR+ +R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL
Sbjct: 1823 NITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSL 1882
Query: 517 TGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDF 576
GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND FS DDF
Sbjct: 1883 GGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDF 1942
Query: 577 LGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL 634
LG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GWWPC
Sbjct: 1943 LGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAE 1995
Query: 635 DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQN 694
+G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W SP +
Sbjct: 1996 EGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKT 2055
Query: 695 FCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 738
+I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP
Sbjct: 2056 MKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2099
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1154 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1211
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1212 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1244
>gi|195976756 dysferlin isoform 10 [Homo sapiens]
Length = 2087
Score = 711 bits (1836), Expect = 0.0
Identities = 369/764 (48%), Positives = 498/764 (65%), Gaps = 47/764 (6%)
Query: 5 SSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWA 64
SSP L+VE G +++++ IR+ + NPNF L + V++P EE Y P+ VKV+DN
Sbjct: 1339 SSPSLVVECGGQTVQSCVIRNLRKNPNF--DICTLFMEVMLPREELYCPPITVKVIDNRQ 1396
Query: 65 FGQQTVTGQANIDFLQPYFCDPWAQDYMHPK---------------LPTLSEKKH----- 104
FG++ V GQ I L+ + CDP++ + P+ L + +K+
Sbjct: 1397 FGRRPVVGQCTIRSLESFLCDPYSAESPSPQGGPDDVSLLSPGEDVLIDIDDKEPLIPIQ 1456
Query: 105 -QDFLGYLYRKFWFK--SSKAEDEYEHEVDWWSKLFWATDEHKSL-KYKYKDYHTLKVYE 160
D L L SS E+E+ +DWWSK F + E + Y KD+ TLKVY+
Sbjct: 1457 LADGLSSLAPTNTASPPSSPHEEEF---IDWWSKFFASIGEREKCGSYLEKDFDTLKVYD 1513
Query: 161 CELEAVPAFQGLQDFCQTFKLYQ---EQPKLDSPVVGEFKGLFRIYPFPENPEAPKPPLQ 217
+LE V AF+GL DFC TFKLY+ ++ D V+GEFKGLF+IYP PE+P P PP Q
Sbjct: 1514 TQLENVEAFEGLSDFCNTFKLYRGKTQEETEDPSVIGEFKGLFKIYPLPEDPAIPMPPRQ 1573
Query: 218 FLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLD 277
F + PQ CLVR+Y+VRA LQP+D NG CDPY+ + +GK + ++D Y P TL+
Sbjct: 1574 FHQLAAQG--PQECLVRIYIVRAFGLQPKDPNGKCDPYIKISIGKKSVSDQDNYIPCTLE 1631
Query: 278 PIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLLSGFGAHCGLSKSY 337
P+FG MFELTC +PLEKDL+I LYD+DL S D+KIG TV+DLENRLLS FGA CGL ++Y
Sbjct: 1632 PVFGKMFELTCTLPLEKDLKITLYDYDLLSKDEKIGETVVDLENRLLSKFGARCGLPQTY 1691
Query: 338 CQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPEEDAVFYNGKKFKLQSFEP-KTPTVH 396
C SGP +WRDQ+ PS LL + ++ + P++ D V + K++ ++ E + P H
Sbjct: 1692 CVSGPNQWRDQLRPSQLLHLFCQQHRVKAPVY--RTDRVMFQDKEYSIEEIEAGRIPNPH 1749
Query: 397 GLGPKKERLALYLLHTQGLVPEHVETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQV 456
LGP +ERLAL++L QGLVPEHVE+R LYS QP I+QGK+QMWVD+FPK LG PGP
Sbjct: 1750 -LGPVEERLALHVLQQQGLVPEHVESRPLYSPLQPDIEQGKLQMWVDLFPKALGRPGPPF 1808
Query: 457 NINPRKPKRYELRCIIWKTANVDLVDDNLSREKTSDIYIKGWLYGLEKDMQKTDIHYHSL 516
NI PR+ +R+ LRCIIW T +V L D +L+ EK SDIY+KGW+ G E+ QKTD+HY SL
Sbjct: 1809 NITPRRARRFFLRCIIWNTRDVILDDLSLTGEKMSDIYVKGWMIGFEEHKQKTDVHYRSL 1868
Query: 517 TGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDF 576
GE +FNWRFIF DYL AE+ C ++KD W LD T K PAR++ Q+WDND FS DDF
Sbjct: 1869 GGEGNFNWRFIFPFDYLPAEQVCTIAKKDAFWRLDKTESKIPARVVFQIWDNDKFSFDDF 1928
Query: 577 LGVLELDLSDMPLPARHAKQCSIRMMD--ADPKWPYFIQYKHFSLFKKKTVTGWWPCQVL 634
LG L+LDL+ MP PA+ AK+CS+ +D P+W SLF++KTV GWWPC
Sbjct: 1929 LGSLQLDLNRMPKPAKTAKKCSLDQLDDAFHPEW-------FVSLFEQKTVKGWWPCVAE 1981
Query: 635 DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQN 694
+G K L+GK++M+LEI++E E +PAG+G+ EPN P L P R +TSF W SP +
Sbjct: 1982 EGEKKILAGKLEMTLEIVAESEHEERPAGQGRDEPNMNPKLEDPRRPDTSFLWFTSPYKT 2041
Query: 695 FCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPHYLAMSWIKP 738
+I W+R+R+ +I F+++ I+ L L FIY+ P+Y AM +KP
Sbjct: 2042 MKFILWRRFRWAIILFIILFILLLFLAIFIYAFPNYAAMKLVKP 2085
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 17/96 (17%)
Query: 233 VRVYMVRAINLQPQDYNGLCDPYVILKLGKTELGNRDMYQPNTLDP------------IF 280
+R YM +A +L D + DPY I+ + + NTL+P IF
Sbjct: 1140 LRCYMYQARDLAAMDKDSFSDPYAIVSF--LHQSQKTVVVKNTLNPTWDQTLIFYEIEIF 1197
Query: 281 GMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTV 316
G + P + ++LYD D + D+ +G +
Sbjct: 1198 GEPATVAEQPP---SIVVELYDHDTYGADEFMGRCI 1230
>gi|35493853 otoferlin isoform c [Homo sapiens]
Length = 1307
Score = 429 bits (1102), Expect = e-120
Identities = 244/602 (40%), Positives = 351/602 (58%), Gaps = 45/602 (7%)
Query: 156 LKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP-------VVGEFKGLFRIY--PFP 206
LKVY ELE+ F +D+ TF L + + D +VG FKG +Y P P
Sbjct: 718 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 775
Query: 207 ENP--EAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTE 264
E+ EA + + P LVRVY+VRA +L P D NG DPY+ ++LGKT+
Sbjct: 776 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 835
Query: 265 LGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLL 324
+ +++ Y L+P+FG F++ + P+E L + +YD+DL DD IG T IDLENR
Sbjct: 836 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 895
Query: 325 SGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE-----EDAVFYN 379
S A CG++++Y G WRD M PS +L R K + P F P + VF
Sbjct: 896 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 955
Query: 380 GKKFKLQSFEPKTPTVHGLGPKKERLALYLL-HTQG-------LVPEHVETRTLYSHSQP 431
+ + ++ + K P E +AL L H + LVPEHVETR L + +P
Sbjct: 956 PSEIEDENGQRK--------PTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKP 1007
Query: 432 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWKTANVDLVDDNL-SREKT 490
GI+QG++++WVD+FP + PG ++I+PRKPK+YELR IIW T V L DD+ + EK+
Sbjct: 1008 GIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKS 1067
Query: 491 SDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSL 550
SDI+++GWL G ++D Q TD+HYHSLTGE +FNWR++F DYLAAE V S+K+ ++S
Sbjct: 1068 SDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSW 1127
Query: 551 DATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMDADPKWPY 610
D T K PARL +Q+WD D FS DDFLG +ELDL+ P A+ AKQC++ M + P
Sbjct: 1128 DETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPL 1187
Query: 611 FIQYKHFSLFKKKTVTGWWPCQVL-DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEP 669
S+FK+K V GWWP + ++ L+GKV+ L +L+ +EA P G ++EP
Sbjct: 1188 ------VSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEP 1241
Query: 670 NQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPH 729
+ L P R +TSF W +P+++ Y W YR+ L+ +++ ++ L+L F+YS P
Sbjct: 1242 D---PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPG 1298
Query: 730 YL 731
YL
Sbjct: 1299 YL 1300
Score = 38.5 bits (88), Expect = 0.025
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 1 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60
+ + P++ +E + +++ I +++ NPNF + V V +P E PL ++VV
Sbjct: 460 LAQVDRPRVDIECAGKGVQSSLIHNYKKNPNF--NTLVKWFEVDLPENELLHPPLNIRVV 517
Query: 61 DNWAFGQQTVTGQANIDFLQPYFCDP 86
D AFG+ T+ G + L+ + P
Sbjct: 518 DCRAFGRYTLVGSHAVSSLRRFIYRP 543
>gi|35493868 otoferlin isoform b [Homo sapiens]
Length = 1230
Score = 429 bits (1102), Expect = e-120
Identities = 244/602 (40%), Positives = 351/602 (58%), Gaps = 45/602 (7%)
Query: 156 LKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP-------VVGEFKGLFRIY--PFP 206
LKVY ELE+ F +D+ TF L + + D +VG FKG +Y P P
Sbjct: 641 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 698
Query: 207 ENP--EAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTE 264
E+ EA + + P LVRVY+VRA +L P D NG DPY+ ++LGKT+
Sbjct: 699 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 758
Query: 265 LGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLL 324
+ +++ Y L+P+FG F++ + P+E L + +YD+DL DD IG T IDLENR
Sbjct: 759 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 818
Query: 325 SGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE-----EDAVFYN 379
S A CG++++Y G WRD M PS +L R K + P F P + VF
Sbjct: 819 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 878
Query: 380 GKKFKLQSFEPKTPTVHGLGPKKERLALYLL-HTQG-------LVPEHVETRTLYSHSQP 431
+ + ++ + K P E +AL L H + LVPEHVETR L + +P
Sbjct: 879 PSEIEDENGQRK--------PTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKP 930
Query: 432 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWKTANVDLVDDNL-SREKT 490
GI+QG++++WVD+FP + PG ++I+PRKPK+YELR IIW T V L DD+ + EK+
Sbjct: 931 GIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKS 990
Query: 491 SDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSL 550
SDI+++GWL G ++D Q TD+HYHSLTGE +FNWR++F DYLAAE V S+K+ ++S
Sbjct: 991 SDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSW 1050
Query: 551 DATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMDADPKWPY 610
D T K PARL +Q+WD D FS DDFLG +ELDL+ P A+ AKQC++ M + P
Sbjct: 1051 DETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPL 1110
Query: 611 FIQYKHFSLFKKKTVTGWWPCQVL-DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEP 669
S+FK+K V GWWP + ++ L+GKV+ L +L+ +EA P G ++EP
Sbjct: 1111 ------VSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEP 1164
Query: 670 NQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPH 729
+ L P R +TSF W +P+++ Y W YR+ L+ +++ ++ L+L F+YS P
Sbjct: 1165 D---PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPG 1221
Query: 730 YL 731
YL
Sbjct: 1222 YL 1223
Score = 43.5 bits (101), Expect = 8e-04
Identities = 60/254 (23%), Positives = 101/254 (39%), Gaps = 41/254 (16%)
Query: 1 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60
+ + P++ +E + +++ I +++ NPNF + V V +P E PL ++VV
Sbjct: 403 LAQVDRPRVDIECAGKGVQSSLIHNYKKNPNF--NTLVKWFEVDLPENELLHPPLNIRVV 460
Query: 61 DNWAFGQQTVTGQANIDFLQPYFCDP-------WAQD-----YMHPKLP----------- 97
D AFG+ T+ G + L+ + P W M P++P
Sbjct: 461 DCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLD 520
Query: 98 -TLSEKKHQDFLGYLYRKFWFKSSKAEDEYEHE-----VDWWSKLFWATDEHK-SLKYKY 150
T D K K AE+ E E +DWWSK F + D K L+ +
Sbjct: 521 ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 580
Query: 151 KDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVGEFKGLFRIYPFPENPE 210
L+ E E++ +G + + +E+ K + G +G E PE
Sbjct: 581 PSGIDLEEKE-EVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQG-------SEAPE 632
Query: 211 APKPPLQFL-VWPE 223
KP + L V+P+
Sbjct: 633 KKKPKIDELKVYPK 646
>gi|34740331 otoferlin isoform a [Homo sapiens]
Length = 1997
Score = 429 bits (1102), Expect = e-120
Identities = 244/602 (40%), Positives = 351/602 (58%), Gaps = 45/602 (7%)
Query: 156 LKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP-------VVGEFKGLFRIY--PFP 206
LKVY ELE+ F +D+ TF L + + D +VG FKG +Y P P
Sbjct: 1408 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 1465
Query: 207 ENP--EAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTE 264
E+ EA + + P LVRVY+VRA +L P D NG DPY+ ++LGKT+
Sbjct: 1466 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 1525
Query: 265 LGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLL 324
+ +++ Y L+P+FG F++ + P+E L + +YD+DL DD IG T IDLENR
Sbjct: 1526 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 1585
Query: 325 SGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE-----EDAVFYN 379
S A CG++++Y G WRD M PS +L R K + P F P + VF
Sbjct: 1586 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 1645
Query: 380 GKKFKLQSFEPKTPTVHGLGPKKERLALYLL-HTQG-------LVPEHVETRTLYSHSQP 431
+ + ++ + K P E +AL L H + LVPEHVETR L + +P
Sbjct: 1646 PSEIEDENGQRK--------PTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKP 1697
Query: 432 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWKTANVDLVDDNL-SREKT 490
GI+QG++++WVD+FP + PG ++I+PRKPK+YELR IIW T V L DD+ + EK+
Sbjct: 1698 GIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKS 1757
Query: 491 SDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSL 550
SDI+++GWL G ++D Q TD+HYHSLTGE +FNWR++F DYLAAE V S+K+ ++S
Sbjct: 1758 SDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSW 1817
Query: 551 DATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMDADPKWPY 610
D T K PARL +Q+WD D FS DDFLG +ELDL+ P A+ AKQC++ M + P
Sbjct: 1818 DETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPL 1877
Query: 611 FIQYKHFSLFKKKTVTGWWPCQVL-DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEP 669
S+FK+K V GWWP + ++ L+GKV+ L +L+ +EA P G ++EP
Sbjct: 1878 ------VSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEP 1931
Query: 670 NQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPH 729
+ L P R +TSF W +P+++ Y W YR+ L+ +++ ++ L+L F+YS P
Sbjct: 1932 D---PLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPG 1988
Query: 730 YL 731
YL
Sbjct: 1989 YL 1990
Score = 38.5 bits (88), Expect = 0.025
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 1 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60
+ + P++ +E + +++ I +++ NPNF + V V +P E PL ++VV
Sbjct: 1150 LAQVDRPRVDIECAGKGVQSSLIHNYKKNPNF--NTLVKWFEVDLPENELLHPPLNIRVV 1207
Query: 61 DNWAFGQQTVTGQANIDFLQPYFCDP 86
D AFG+ T+ G + L+ + P
Sbjct: 1208 DCRAFGRYTLVGSHAVSSLRRFIYRP 1233
>gi|119120884 fer-1-like 6 [Homo sapiens]
Length = 1857
Score = 426 bits (1095), Expect = e-119
Identities = 248/669 (37%), Positives = 362/669 (54%), Gaps = 79/669 (11%)
Query: 118 KSSKAEDEYEHEVDWWSKLFWATDE----------------------------------- 142
K + A++ E+ +DWWSK + + +
Sbjct: 1199 KRTIADESAENVIDWWSKYYASLKKAQKAKERNPKGKKGNTEAKPDEVVVDIEDGPKKKK 1258
Query: 143 HKSLKYKYKD-----YHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP------ 191
K LK K KD L++Y+ +LE+ F +D+ +TF+L++ + D
Sbjct: 1259 DKMLKKKPKDDGIPNLAILQIYDGDLES--EFNNFEDWVKTFELFRGKSTEDDHGLDGDR 1316
Query: 192 VVGEFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGL 251
V+G+FKG F IY P++ + + + P L+RVY+V A NL P D +G
Sbjct: 1317 VIGKFKGSFCIYKSPQDSSSEDSGQLRIQQGIPPNHPVTVLIRVYIVAAFNLSPADPDGK 1376
Query: 252 CDPYVILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDK 311
DPY+++KLGKTE+ +RD Y P L+P+FG FE+ P E L I +YD D+ DD
Sbjct: 1377 SDPYIVIKLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSILIYDHDMIGTDDL 1436
Query: 312 IGTTVIDLENRLLSGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSP 371
IG T IDLENR S A CGL Y G WRD P+ +L + K L P F P
Sbjct: 1437 IGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFHP 1496
Query: 372 EEDAV---FYNGKKFKLQSFEPKTPTVHGLGPKKERLALYLLHTQG--------LVPEHV 420
+ + ++GK + +T + E LAL +LH+ LVPEH+
Sbjct: 1497 GKIQIGNQVFSGKTIFTEEDTDETVESY------EHLALKVLHSWEDIPEVGCRLVPEHI 1550
Query: 421 ETRTLYSHSQPGIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWKTANVDL 480
ETR LY +PG++QG++QMWVD+FPK + PGP V+I+PR+PK YELR IW T +V L
Sbjct: 1551 ETRPLYHKDKPGMEQGRLQMWVDMFPKDMPQPGPPVDISPRRPKGYELRVTIWNTEDVIL 1610
Query: 481 VDDNL-SREKTSDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTC 539
D+N+ + +K+SDIY+KGWL GLE D Q+TD+HY+SLTGE +FNWRF+F YL AE+
Sbjct: 1611 EDENIFTGQKSSDIYVKGWLKGLEDDKQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQM 1670
Query: 540 VQSQKDYIWSLDATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSI 599
V ++++ I+SL+ K PA L++QVWD + S DDFLG LE++L+ P A+ AK C +
Sbjct: 1671 VITKRENIFSLEKMECKTPAVLVLQVWDFERLSSDDFLGTLEMNLNSFPRAAKSAKACDL 1730
Query: 600 RMMDADPKWPYFIQYKHFSLFKKKTVTGWWPCQVLDGGKWRLSGKVKMSLEILSEKEALI 659
K+ + S+F++K V GWWP L+GKV+ +++ +EA
Sbjct: 1731 ------AKFENASEETKISIFQQKRVRGWWPF----SKSKELTGKVEAEFHLVTAEEAEK 1780
Query: 660 KPAGRGQSEPNQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALM 719
P G+ + EP L P R +TSF+W SP + Y+ WK Y+ +I ++ I+ +
Sbjct: 1781 NPVGKARKEPE---PLAKPNRPDTSFSWFMSPFKCLYYLIWKNYKKYIIIAFILIILIIF 1837
Query: 720 LFNFIYSAP 728
L FIY+ P
Sbjct: 1838 LVLFIYTLP 1846
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
Query: 7 PQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVVDNWAFG 66
PQ L+E G + +++ I+ ++ NPNF S V +P E PL + VVD AFG
Sbjct: 1015 PQALIECGGQGVKSCVIQSYKNNPNF--SIQADAFEVELPENELLHPPLSICVVDWRAFG 1072
Query: 67 QQTVTGQANIDFLQPYFC 84
+ T+ G I++L+ + C
Sbjct: 1073 RSTLVGTYTINYLKQFLC 1090
>gi|35493860 otoferlin isoform d [Homo sapiens]
Length = 1230
Score = 421 bits (1083), Expect = e-117
Identities = 242/602 (40%), Positives = 350/602 (58%), Gaps = 45/602 (7%)
Query: 156 LKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSP-------VVGEFKGLFRIY--PFP 206
LKVY ELE+ F +D+ TF L + + D +VG FKG +Y P P
Sbjct: 641 LKVYPKELES--EFDNFEDWLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLCVYKVPLP 698
Query: 207 ENP--EAPKPPLQFLVWPEREDFPQPCLVRVYMVRAINLQPQDYNGLCDPYVILKLGKTE 264
E+ EA + + P LVRVY+VRA +L P D NG DPY+ ++LGKT+
Sbjct: 699 EDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTD 758
Query: 265 LGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDLENRLL 324
+ +++ Y L+P+FG F++ + P+E L + +YD+DL DD IG T IDLENR
Sbjct: 759 IRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFY 818
Query: 325 SGFGAHCGLSKSYCQSGPFRWRDQMPPSYLLERYAKRKGLPPPLFSPE-----EDAVFYN 379
S A CG++++Y G WRD M PS +L R K + P F P + VF
Sbjct: 819 SKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTG 878
Query: 380 GKKFKLQSFEPKTPTVHGLGPKKERLALYLL-HTQG-------LVPEHVETRTLYSHSQP 431
+ + ++ + K P E +AL L H + LVPEHVETR L + +P
Sbjct: 879 PSEIEDENGQRK--------PTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKP 930
Query: 432 GIDQGKVQMWVDIFPKKLGPPGPQVNINPRKPKRYELRCIIWKTANVDLVDDNL-SREKT 490
GI+QG++++WVD+FP + PG ++I+PRKPK+YELR IIW T V L DD+ + EK+
Sbjct: 931 GIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKS 990
Query: 491 SDIYIKGWLYGLEKDMQKTDIHYHSLTGEADFNWRFIFTMDYLAAERTCVQSQKDYIWSL 550
SDI+++GWL G ++D Q TD+HYHSLTGE +FNWR++F DYLAAE V S+K+ ++S
Sbjct: 991 SDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSW 1050
Query: 551 DATSMKFPARLIIQVWDNDIFSPDDFLGVLELDLSDMPLPARHAKQCSIRMMDADPKWPY 610
D T K PARL +Q+WD D FS DDFLG +ELDL+ P A+ AKQC++ M + P
Sbjct: 1051 DETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPL 1110
Query: 611 FIQYKHFSLFKKKTVTGWWPCQVL-DGGKWRLSGKVKMSLEILSEKEALIKPAGRGQSEP 669
S+FK+K V GWWP + ++ L+GKV+ L +L+ +EA P G ++EP
Sbjct: 1111 ------VSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEP 1164
Query: 670 NQYPTLHPPLRTNTSFTWLRSPVQNFCYIFWKRYRFKLIAFMVISIIALMLFNFIYSAPH 729
+ L P R +T+F W +P+++ Y+ RY++ +I ++ + LML F+YS P
Sbjct: 1165 D---PLEKPNRPDTAFVWFLNPLKSIKYLICTRYKWLIIKIVLALLGLLMLGLFLYSLPG 1221
Query: 730 YL 731
Y+
Sbjct: 1222 YM 1223
Score = 43.5 bits (101), Expect = 8e-04
Identities = 60/254 (23%), Positives = 101/254 (39%), Gaps = 41/254 (16%)
Query: 1 MKKASSPQLLVEFGEESLRTEPIRDFQTNPNFPESESVLVLTVLMPTEEAYALPLVVKVV 60
+ + P++ +E + +++ I +++ NPNF + V V +P E PL ++VV
Sbjct: 403 LAQVDRPRVDIECAGKGVQSSLIHNYKKNPNF--NTLVKWFEVDLPENELLHPPLNIRVV 460
Query: 61 DNWAFGQQTVTGQANIDFLQPYFCDP-------WAQD-----YMHPKLP----------- 97
D AFG+ T+ G + L+ + P W M P++P
Sbjct: 461 DCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPSWNTTGEVVVTMEPEVPIKKLETMVKLD 520
Query: 98 -TLSEKKHQDFLGYLYRKFWFKSSKAEDEYEHE-----VDWWSKLFWATDEHK-SLKYKY 150
T D K K AE+ E E +DWWSK F + D K L+ +
Sbjct: 521 ATSEAVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQE 580
Query: 151 KDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVGEFKGLFRIYPFPENPE 210
L+ E E++ +G + + +E+ K + G +G E PE
Sbjct: 581 PSGIDLEEKE-EVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQG-------SEAPE 632
Query: 211 APKPPLQFL-VWPE 223
KP + L V+P+
Sbjct: 633 KKKPKIDELKVYPK 646
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 48.9 bits (115), Expect = 2e-05
Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 239 RAINLQPQDYNGLCDPYV-ILKLGKTELGNRDMYQPNTLDPIFG--MMFELTCNIPLEKD 295
+A+NL +D++G DPYV I L + ++ TL+P+F +F + N +
Sbjct: 243 KAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARK 302
Query: 296 LEIQLYDFDLFSPDDKIGTTVID 318
L +YDFD FS D IG V+D
Sbjct: 303 LHFSVYDFDRFSRHDLIGQVVVD 325
Score = 33.5 bits (75), Expect = 0.80
Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Query: 235 VYMVRAINLQPQDYNGLCDPYVILKL---GKTELGNRDMYQPNTLDPIF--GMMFELTCN 289
+ +++A NL+ D G DPYV + L G+ + + NTL+P++ ++F++
Sbjct: 371 ITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPE 430
Query: 290 IPLEKDLEIQLYDFDLFSPDDKIGTTVIDLE 320
+ L I + D+D ++ IG + E
Sbjct: 431 NIDQIHLSIAVMDYDRVGHNEIIGVCQVGNE 461
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 7/89 (7%)
Query: 235 VYMVRAINLQPQDYNGLCDPYV-ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPL- 292
V +++A++L +D NG DPYV I L + + TL+P+F F+ + +PL
Sbjct: 318 VRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFS--VPLA 375
Query: 293 ---EKDLEIQLYDFDLFSPDDKIGTTVID 318
++ L +YDFD FS D IG V+D
Sbjct: 376 ELAQRKLHFSVYDFDRFSRHDLIGQVVLD 404
Score = 35.8 bits (81), Expect = 0.16
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 235 VYMVRAINLQPQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIF--GMMFELTCN 289
V +++A NL+ D G DPYV ++ G+ + + NTL+P + ++F++
Sbjct: 450 VTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPE 509
Query: 290 IPLEKDLEIQLYDFDLFSPDDKIG 313
L I + D+D ++ IG
Sbjct: 510 SVENVGLSIAVVDYDCIGHNEVIG 533
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 7/89 (7%)
Query: 235 VYMVRAINLQPQDYNGLCDPYV-ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPL- 292
V +++A++L +D NG DPYV I L + + TL+P+F F+ + +PL
Sbjct: 318 VRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFS--VPLA 375
Query: 293 ---EKDLEIQLYDFDLFSPDDKIGTTVID 318
++ L +YDFD FS D IG V+D
Sbjct: 376 ELAQRKLHFSVYDFDRFSRHDLIGQVVLD 404
Score = 35.8 bits (81), Expect = 0.16
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 235 VYMVRAINLQPQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIF--GMMFELTCN 289
V +++A NL+ D G DPYV ++ G+ + + NTL+P + ++F++
Sbjct: 450 VTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPE 509
Query: 290 IPLEKDLEIQLYDFDLFSPDDKIG 313
L I + D+D ++ IG
Sbjct: 510 SVENVGLSIAVVDYDCIGHNEVIG 533
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 7/89 (7%)
Query: 235 VYMVRAINLQPQDYNGLCDPYV-ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPL- 292
V +++A++L +D NG DPYV I L + + TL+P+F F+ + +PL
Sbjct: 318 VRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFS--VPLA 375
Query: 293 ---EKDLEIQLYDFDLFSPDDKIGTTVID 318
++ L +YDFD FS D IG V+D
Sbjct: 376 ELAQRKLHFSVYDFDRFSRHDLIGQVVLD 404
Score = 35.8 bits (81), Expect = 0.16
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 235 VYMVRAINLQPQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIF--GMMFELTCN 289
V +++A NL+ D G DPYV ++ G+ + + NTL+P + ++F++
Sbjct: 450 VTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPE 509
Query: 290 IPLEKDLEIQLYDFDLFSPDDKIG 313
L I + D+D ++ IG
Sbjct: 510 SVENVGLSIAVVDYDCIGHNEVIG 533
>gi|103472031 family with sequence similarity 62 (C2 domain
containing), member C [Homo sapiens]
Length = 886
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 227 FPQPC-LVRVYMVRAINLQPQD----YNGLCDPYVILKLGKTELGNRDMYQPNTLDPIFG 281
FP PC ++RV+++ A L +D G DPY + +G +R +Y+ L+P +
Sbjct: 301 FPLPCGVIRVHLLEAEQLAQKDNFLGLRGKSDPYAKVSIGLQHFRSRTIYR--NLNPTWN 358
Query: 282 MMFELTCNIPLEKDLEIQLYDFDLFSPDDKIGTTVIDL 319
+FE +DLE+ LYD D DD +G+ I L
Sbjct: 359 EVFEFMVYEVPGQDLEVDLYDEDT-DRDDFLGSLQICL 395
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/200 (24%), Positives = 77/200 (38%), Gaps = 29/200 (14%)
Query: 135 KLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVG 194
K F K+L + + T KV EL + DF + K ++G
Sbjct: 192 KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSK---------HDIIG 242
Query: 195 EFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCL----------VRVYMVRAINLQ 244
EFK F E + LQ E+E C + V ++ A NL+
Sbjct: 243 EFKVPMNTVDFGHVTEEWRD-LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLK 301
Query: 245 PQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQ-- 299
D GL DPYV +++ GK + + NTL+P + F +P E+ ++Q
Sbjct: 302 KMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSF--EVPFEQIQKVQVV 359
Query: 300 --LYDFDLFSPDDKIGTTVI 317
+ D+D +D IG +
Sbjct: 360 VTVLDYDKIGKNDAIGKVFV 379
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/200 (24%), Positives = 77/200 (38%), Gaps = 29/200 (14%)
Query: 135 KLFWATDEHKSLKYKYKDYHTLKVYECELEAVPAFQGLQDFCQTFKLYQEQPKLDSPVVG 194
K F K+L + + T KV EL + DF + K ++G
Sbjct: 192 KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSK---------HDIIG 242
Query: 195 EFKGLFRIYPFPENPEAPKPPLQFLVWPEREDFPQPCL----------VRVYMVRAINLQ 244
EFK F E + LQ E+E C + V ++ A NL+
Sbjct: 243 EFKVPMNTVDFGHVTEEWRD-LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLK 301
Query: 245 PQDYNGLCDPYV---ILKLGKTELGNRDMYQPNTLDPIFGMMFELTCNIPLEKDLEIQ-- 299
D GL DPYV +++ GK + + NTL+P + F +P E+ ++Q
Sbjct: 302 KMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSF--EVPFEQIQKVQVV 359
Query: 300 --LYDFDLFSPDDKIGTTVI 317
+ D+D +D IG +
Sbjct: 360 VTVLDYDKIGKNDAIGKVFV 379
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,524,547
Number of Sequences: 37866
Number of extensions: 1795598
Number of successful extensions: 3995
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 3615
Number of HSP's gapped (non-prelim): 246
length of query: 802
length of database: 18,247,518
effective HSP length: 110
effective length of query: 692
effective length of database: 14,082,258
effective search space: 9744922536
effective search space used: 9744922536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.