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Search of human proteins with 23943900
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23943900 transmembrane channel-like 8 [Homo sapiens]
(726 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23943900 transmembrane channel-like 8 [Homo sapiens] 1476 0.0
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens] 366 e-101
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens] 363 e-100
gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens] 332 1e-90
gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens] 332 1e-90
gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens] 197 3e-50
gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens] 197 3e-50
gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens] 187 3e-47
gi|187608784 transmembrane channel-like 6 [Homo sapiens] 171 2e-42
gi|187608791 transmembrane channel-like 6 [Homo sapiens] 171 2e-42
gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap... 154 4e-37
gi|21071070 transmembrane channel-like 1 [Homo sapiens] 152 1e-36
gi|122937502 transmembrane channel-like 3 [Homo sapiens] 108 1e-23
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 40 0.008
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 39 0.013
gi|56606142 complement component 1, q subcomponent-like 4 [Homo ... 39 0.017
gi|134244285 Notch homolog 3 [Homo sapiens] 38 0.029
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 38 0.038
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 37 0.050
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 37 0.084
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 37 0.084
gi|195972903 zinc finger protein 385A isoform a [Homo sapiens] 37 0.084
gi|24308079 zinc finger protein 385A isoform c [Homo sapiens] 37 0.084
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 36 0.11
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 36 0.11
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 36 0.14
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 35 0.19
gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens] 35 0.19
gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens] 35 0.19
gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens] 35 0.19
>gi|23943900 transmembrane channel-like 8 [Homo sapiens]
Length = 726
Score = 1476 bits (3820), Expect = 0.0
Identities = 726/726 (100%), Positives = 726/726 (100%)
Query: 1 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 60
MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
Sbjct: 1 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 60
Query: 61 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 120
LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
Sbjct: 61 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 120
Query: 121 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 180
LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
Sbjct: 121 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 180
Query: 181 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 240
NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
Sbjct: 181 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 240
Query: 241 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL 300
PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL
Sbjct: 241 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL 300
Query: 301 RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ 360
RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ
Sbjct: 301 RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ 360
Query: 361 LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE 420
LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE
Sbjct: 361 LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE 420
Query: 421 NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA 480
NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA
Sbjct: 421 NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA 480
Query: 481 GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL 540
GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL
Sbjct: 481 GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL 540
Query: 541 GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS 600
GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS
Sbjct: 541 GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS 600
Query: 601 FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG 660
FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG
Sbjct: 601 FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG 660
Query: 661 PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF 720
PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF
Sbjct: 661 PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF 720
Query: 721 PSGAEL 726
PSGAEL
Sbjct: 721 PSGAEL 726
>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
Length = 723
Score = 366 bits (940), Expect = e-101
Identities = 220/638 (34%), Positives = 352/638 (55%), Gaps = 30/638 (4%)
Query: 32 SGTPVRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVERRLREAAQRLARGLGLW 91
S +R + +KR + ++E W +W+R +R E A+ + L LW
Sbjct: 86 SSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQWKRYSSKSWKRFLEKAREMTTHLELW 145
Query: 92 EGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPG------P 145
+ I G FGTGI+SYF+FLRFL+LLNL+ L+ VLLP++ + P
Sbjct: 146 REDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIP 205
Query: 146 TLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYRVGPES--SSVYSIR 202
++ QC S G++ F++ + +L+G F T LFYG Y + + Y +
Sbjct: 206 FKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLP 265
Query: 203 LAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATI 262
LAYLLS +A L L ++R V+G + + + K+F+ WDFCI + A +
Sbjct: 266 LAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADL 325
Query: 263 KKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISAIFWATK 322
K + E + +LEE R Q + ++T +T L +N + ++ AI+ AT
Sbjct: 326 KHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATV 385
Query: 323 YSQDNKE---------ESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT 373
+SQ++ + E+LF+L YLP VI L NF+ P++F +++ E+Y P E+ LT
Sbjct: 386 FSQEHMKKEIDKMVFGENLFIL--YLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRLT 443
Query: 374 LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF 433
++ CV ++LA++ + +LG I D +C+ GYN Y CWE VG+E+YKL IF
Sbjct: 444 ILRCVFMRLATICVLVFTLGSKITSC--DDDTCDLCGYNQKLYPCWETQVGQEMYKLMIF 501
Query: 434 NFLLTVAFAFLVTLPRRLLVDRFSG----RFWAWLEREEFLVPKNVLDIVAGQTVTWMGL 489
+F++ +A V PR+LLV S + W ++EF +P NVL IV GQT+ W+G
Sbjct: 502 DFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWG---QQEFAIPDNVLGIVYGQTICWIGA 558
Query: 490 FYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPL 549
F+ PLLP + ++ + FY+K+++LL R S RPFRAS+S FFF LVLL+GL LA +PL
Sbjct: 559 FFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAIIPL 618
Query: 550 GYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSL 609
+S I SS CG FTN++ W+V+P+ V+ P Q +H + S AF+ P +++ L
Sbjct: 619 TISISRIPSSKACGPFTNFNTTWEVIPKTVST-FPSSLQSFIHGVTSEAFAVPFFMIICL 677
Query: 610 VLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLS 647
++ ++ A+ R + +LR+QL + ++K +L++ L+
Sbjct: 678 IMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQKLT 715
>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
Length = 613
Score = 363 bits (932), Expect = e-100
Identities = 215/607 (35%), Positives = 341/607 (56%), Gaps = 30/607 (4%)
Query: 63 WQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLL 122
W +W+R +R E A+ + L LW + I G FGTGI+SYF+FLRFL+LLNL+
Sbjct: 7 WDQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLV 66
Query: 123 SLLLTASFVLLPLVWLRPPDPG------PTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTG 176
L+ VLLP++ + P ++ QC S G++ F++ + +L+G
Sbjct: 67 IFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSG 126
Query: 177 RAFTN-TYLFYGAYRVGPES--SSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTL 233
F T LFYG Y + + Y + LAYLLS +A L L ++R V+G +
Sbjct: 127 TGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLI 186
Query: 234 LGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTA 293
+ + K+F+ WDFCI + A +K + E + +LEE R Q + ++T +T
Sbjct: 187 RSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETI 246
Query: 294 CRLLSYLRVNVLNGLLVVGAISAIFWATKYSQDNKE---------ESLFLLLQYLPPGVI 344
L +N + ++ AI+ AT +SQ++ + E+LF+L YLP VI
Sbjct: 247 RIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFIL--YLPSIVI 304
Query: 345 ALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKS 404
L NF+ P++F +++ E+Y P E+ LT++ CV ++LA++ + +LG I D
Sbjct: 305 TLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSC--DDD 362
Query: 405 SCESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSG----RF 460
+C+ GYN Y CWE VG+E+YKL IF+F++ +A V PR+LLV S +
Sbjct: 363 TCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQC 422
Query: 461 WAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRA 520
W ++EF +P NVL IV GQT+ W+G F+ PLLP + ++ + FY+K+++LL R
Sbjct: 423 WG---QQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRP 479
Query: 521 SSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVA 580
S RPFRAS+S FFF LVLL+GL LA +PL +S I SS CG FTN++ W+V+P+ V+
Sbjct: 480 SPRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVS 539
Query: 581 LGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKW 640
P Q +H + S AF+ P +++ L++ ++ A+ R + +LR+QL + ++K
Sbjct: 540 T-FPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKC 598
Query: 641 HLVEDLS 647
+L++ L+
Sbjct: 599 YLIQKLT 605
>gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens]
Length = 706
Score = 332 bits (850), Expect = 1e-90
Identities = 225/626 (35%), Positives = 322/626 (51%), Gaps = 40/626 (6%)
Query: 35 PVRGLPYAMMDKRLIWQLREP-------AGVQTLRWQRWQRRRQTVERRLREAAQRLARG 87
P R LP+ M +R Q +G +T RW R + RR +E + R
Sbjct: 83 PSRELPWPMQARRAHRQRNASRDQVVYGSGTKTDRWAR-------LLRRSKEKTKEGLRS 135
Query: 88 LGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPT- 146
L W L IGG FG G SYF+ LRFLLLLN+L+ +L A LLP WL PGP
Sbjct: 136 LQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLP-TWLGGAPPGPPG 194
Query: 147 LNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYRVGPESSSVYSIRLAY 205
+++ C G++ F QL+++L+G + + LFYG Y P + + Y
Sbjct: 195 PDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRPR------LAVTY 248
Query: 206 LLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKH 265
L A L+C L R V GL Q L S +VFS+WDF + +++
Sbjct: 249 LCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQR 308
Query: 266 EISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISA----IFWAT 321
I E KVELEE ++++Q +T + V VL LLVV + A ++WAT
Sbjct: 309 IILYELKVELEE----TVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWAT 364
Query: 322 KYSQDNKEESLF-------LLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTL 374
+ + +E L L + YLP IA VNF+ P +F + LE Y + ++ L
Sbjct: 365 GCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFIL 424
Query: 375 IWCVVLKLASLGMFSVSLGQTILCIGRDKSS-CESYGYNVCDYQCWENSVGEELYKLSIF 433
+ V L+LASL + SL I C G ++ C++ GYN CWE +G+E+YKL +F
Sbjct: 425 LRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLF 484
Query: 434 NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP 493
+ L +A A L+ PR+LL G +EF VP VL ++ QTV W+G F+CP
Sbjct: 485 DLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGSFFCP 544
Query: 494 LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV 553
LLPLLN+V L FY+KK TL ++R FRAS++ FFF LVLLLGL +++VPL Y +
Sbjct: 545 LLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPLLYSI 604
Query: 554 SSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTV 613
I S CG F S+ W +PE ++ LP Q L +LG+ AF+ PLL++ S+++
Sbjct: 605 FLIPPSKLCGPFRGQSSIWAQIPESIS-SLPETTQNFLFFLGTQAFAVPLLLISSILMAY 663
Query: 614 CVSQTQANARAIHRLRKQLVWQVQEK 639
V+ + R I L++Q + Q K
Sbjct: 664 TVALANSYGRLISELKRQRQTEAQNK 689
>gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens]
Length = 712
Score = 332 bits (850), Expect = 1e-90
Identities = 225/626 (35%), Positives = 322/626 (51%), Gaps = 40/626 (6%)
Query: 35 PVRGLPYAMMDKRLIWQLREP-------AGVQTLRWQRWQRRRQTVERRLREAAQRLARG 87
P R LP+ M +R Q +G +T RW R + RR +E + R
Sbjct: 89 PSRELPWPMQARRAHRQRNASRDQVVYGSGTKTDRWAR-------LLRRSKEKTKEGLRS 141
Query: 88 LGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPT- 146
L W L IGG FG G SYF+ LRFLLLLN+L+ +L A LLP WL PGP
Sbjct: 142 LQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLP-TWLGGAPPGPPG 200
Query: 147 LNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYRVGPESSSVYSIRLAY 205
+++ C G++ F QL+++L+G + + LFYG Y P + + Y
Sbjct: 201 PDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRPR------LAVTY 254
Query: 206 LLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKH 265
L A L+C L R V GL Q L S +VFS+WDF + +++
Sbjct: 255 LCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQR 314
Query: 266 EISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISA----IFWAT 321
I E KVELEE ++++Q +T + V VL LLVV + A ++WAT
Sbjct: 315 IILYELKVELEE----TVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWAT 370
Query: 322 KYSQDNKEESLF-------LLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTL 374
+ + +E L L + YLP IA VNF+ P +F + LE Y + ++ L
Sbjct: 371 GCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFIL 430
Query: 375 IWCVVLKLASLGMFSVSLGQTILCIGRDKSS-CESYGYNVCDYQCWENSVGEELYKLSIF 433
+ V L+LASL + SL I C G ++ C++ GYN CWE +G+E+YKL +F
Sbjct: 431 LRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLF 490
Query: 434 NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP 493
+ L +A A L+ PR+LL G +EF VP VL ++ QTV W+G F+CP
Sbjct: 491 DLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGSFFCP 550
Query: 494 LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV 553
LLPLLN+V L FY+KK TL ++R FRAS++ FFF LVLLLGL +++VPL Y +
Sbjct: 551 LLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPLLYSI 610
Query: 554 SSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTV 613
I S CG F S+ W +PE ++ LP Q L +LG+ AF+ PLL++ S+++
Sbjct: 611 FLIPPSKLCGPFRGQSSIWAQIPESIS-SLPETTQNFLFFLGTQAFAVPLLLISSILMAY 669
Query: 614 CVSQTQANARAIHRLRKQLVWQVQEK 639
V+ + R I L++Q + Q K
Sbjct: 670 TVALANSYGRLISELKRQRQTEAQNK 695
>gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens]
Length = 1006
Score = 197 bits (501), Expect = 3e-50
Identities = 153/591 (25%), Positives = 274/591 (46%), Gaps = 64/591 (10%)
Query: 75 RRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP 134
RR + + + + LW+ L IGG FGT + SYF FLR+LL N+ S +L SF+++P
Sbjct: 415 RRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIP 474
Query: 135 LVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGP- 193
+ + TLQ G L F + + F +T ++YG Y
Sbjct: 475 QFTVAKKN-------TLQFTG--------LEFFTGVGY------FRDTVMYYGFYTNSTI 513
Query: 194 ---ESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSW 250
S + Y+++LAY+ + ACL CF L M K + Y ++ +F W
Sbjct: 514 QHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 572
Query: 251 DFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLV 310
DF + ++A +K+ +S E + L E R Q + T Q R +Y+ V++ +
Sbjct: 573 DFTVTHEKAVKLKQKNLSTEIRENLSELR--QENSKLTFNQLLTRFSAYMVAWVVSTGVA 630
Query: 311 VGAISAIFWATKYSQD----NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYP- 365
+ +A+++ +Y+ + + LLL P V++ +N P +++ +E Y
Sbjct: 631 IACCAAVYYLAEYNLEFLKTHSNPGAVLLL----PFVVSCINLAVPCIYSMFRLVERYEM 686
Query: 366 PNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGE 425
P EV + LI + LK++ +G+ T+ G + CWE +G+
Sbjct: 687 PRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE---------------CWETLIGQ 731
Query: 426 ELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVT 485
++Y+L + +F+ ++ +FL RR++ + L +EF + +NVL+++ QT+
Sbjct: 732 DIYRLLLMDFVFSLVNSFLGEFLRRII----GMQLITSLGLQEFDIARNVLELIYAQTLV 787
Query: 486 WMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASS-STFFFQLVLLLGLLL 544
W+G+F+CPLLP + + LF+ FY K +L+ N + S+ +RAS TFF L+
Sbjct: 788 WIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTG 847
Query: 545 AAVPLGYVVSSIHSSWDCG------LFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHA 598
L + + S DCG LF + W + G + + +GS
Sbjct: 848 VLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSW-IDTLSTRPGYLWVVWIYRNLIGSVH 906
Query: 599 FSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRL 649
F F L +++ ++ + T+ I L +Q++ + ++K L+E L +L
Sbjct: 907 FFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKL 957
>gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens]
Length = 760
Score = 197 bits (501), Expect = 3e-50
Identities = 153/591 (25%), Positives = 274/591 (46%), Gaps = 64/591 (10%)
Query: 75 RRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP 134
RR + + + + LW+ L IGG FGT + SYF FLR+LL N+ S +L SF+++P
Sbjct: 169 RRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIP 228
Query: 135 LVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGP- 193
+ + TLQ G L F + + F +T ++YG Y
Sbjct: 229 QFTVAKKN-------TLQFTG--------LEFFTGVGY------FRDTVMYYGFYTNSTI 267
Query: 194 ---ESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSW 250
S + Y+++LAY+ + ACL CF L M K + Y ++ +F W
Sbjct: 268 QHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 326
Query: 251 DFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLV 310
DF + ++A +K+ +S E + L E R Q + T Q R +Y+ V++ +
Sbjct: 327 DFTVTHEKAVKLKQKNLSTEIRENLSELR--QENSKLTFNQLLTRFSAYMVAWVVSTGVA 384
Query: 311 VGAISAIFWATKYSQD----NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYP- 365
+ +A+++ +Y+ + + LLL P V++ +N P +++ +E Y
Sbjct: 385 IACCAAVYYLAEYNLEFLKTHSNPGAVLLL----PFVVSCINLAVPCIYSMFRLVERYEM 440
Query: 366 PNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGE 425
P EV + LI + LK++ +G+ T+ G + CWE +G+
Sbjct: 441 PRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE---------------CWETLIGQ 485
Query: 426 ELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVT 485
++Y+L + +F+ ++ +FL RR++ + L +EF + +NVL+++ QT+
Sbjct: 486 DIYRLLLMDFVFSLVNSFLGEFLRRII----GMQLITSLGLQEFDIARNVLELIYAQTLV 541
Query: 486 WMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASS-STFFFQLVLLLGLLL 544
W+G+F+CPLLP + + LF+ FY K +L+ N + S+ +RAS TFF L+
Sbjct: 542 WIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTG 601
Query: 545 AAVPLGYVVSSIHSSWDCG------LFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHA 598
L + + S DCG LF + W + G + + +GS
Sbjct: 602 VLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSW-IDTLSTRPGYLWVVWIYRNLIGSVH 660
Query: 599 FSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRL 649
F F L +++ ++ + T+ I L +Q++ + ++K L+E L +L
Sbjct: 661 FFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKL 711
>gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens]
Length = 948
Score = 187 bits (475), Expect = 3e-47
Identities = 129/473 (27%), Positives = 228/473 (48%), Gaps = 56/473 (11%)
Query: 75 RRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP 134
RR + + + + LW+ L IGG FGT + SYF FLR+LL N+ S +L SF+++P
Sbjct: 415 RRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIP 474
Query: 135 LVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGP- 193
+ + TLQ G L F + + F +T ++YG Y
Sbjct: 475 QFTVAKKN-------TLQFTG--------LEFFTGVGY------FRDTVMYYGFYTNSTI 513
Query: 194 ---ESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSW 250
S + Y+++LAY+ + ACL CF L M K + Y ++ +F W
Sbjct: 514 QHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-W 572
Query: 251 DFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLV 310
DF + ++A +K+ +S E + L E R Q + T Q R +Y+ V++ +
Sbjct: 573 DFTVTHEKAVKLKQKNLSTEIRENLSELR--QENSKLTFNQLLTRFSAYMVAWVVSTGVA 630
Query: 311 VGAISAIFWATKYSQD----NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYP- 365
+ +A+++ +Y+ + + LLL P V++ +N P +++ +E Y
Sbjct: 631 IACCAAVYYLAEYNLEFLKTHSNPGAVLLL----PFVVSCINLAVPCIYSMFRLVERYEM 686
Query: 366 PNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGE 425
P EV + LI + LK++ +G+ T+ G + CWE +G+
Sbjct: 687 PRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE---------------CWETLIGQ 731
Query: 426 ELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVT 485
++Y+L + +F+ ++ +FL RR++ + L +EF + +NVL+++ QT+
Sbjct: 732 DIYRLLLMDFVFSLVNSFLGEFLRRII----GMQLITSLGLQEFDIARNVLELIYAQTLV 787
Query: 486 WMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVL 538
W+G+F+CPLLP + + LF+ FY K +L+ N + S+ +RAS FF +L
Sbjct: 788 WIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLL 840
>gi|187608784 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 171 bits (434), Expect = 2e-42
Identities = 190/670 (28%), Positives = 293/670 (43%), Gaps = 122/670 (18%)
Query: 36 VRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVE--RRLREAAQRLARGLGL--- 90
+RG+P ++ +KR LRE + +W+ RLR A LGL
Sbjct: 165 LRGMPLSLAEKR---SLREKSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALL 221
Query: 91 --------WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPD 142
W AL IGG FG+ + SYF FL+ LL N L LLL +F++ P V P
Sbjct: 222 SALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPAL 281
Query: 143 PGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRA-FTNTYLFYGAY------------ 189
PGP C G +LTG FT+T ++YG Y
Sbjct: 282 PGPAP----VCTGLE---------------LLTGAGCFTHTVMYYGHYSNATLNQPCGSP 322
Query: 190 --------RVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAP 241
RVG Y++ LAYL S + C TL V + G+ Y+
Sbjct: 323 LDGSQCTPRVG---GLPYNMPLAYL-STVGVSFFITCITL---VYSMAHS--FGESYRVG 373
Query: 242 LSA-----KVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRL 296
++ VF SWD+ + + A+ +++ I K L E Q + ++ C
Sbjct: 374 STSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAE------WQLRHSPRSVCGR 427
Query: 297 LSYLRVNVLNGLLVVG-----AISAIFWATKYSQDNK---EESLFLLLQYLPPGVIALVN 348
L V L LL +G A++ ++ Q + +E++ L+L P V+ L+N
Sbjct: 428 LRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVL----PLVVGLLN 483
Query: 349 FLGPLLFTFLVQLENYP-PNTEVNLTLIWCVVLKLASLGMFSVS-LGQTILCIGRDKSSC 406
P L L LE + P EV + + ++LKLA LG LG+ +
Sbjct: 484 LGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRV---------- 533
Query: 407 ESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLER 466
V QCWE+ VG+ELY+ + +F+L + L R++ ++ R +
Sbjct: 534 -----GVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKR----RRK 584
Query: 467 EEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFR 526
EF + +NVL+++ GQT+TW+G+ + PLLP + + L L FY+KK +LL N +A RP+
Sbjct: 585 PEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWL 644
Query: 527 AS-SSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLF----TNYSAPWQVVPELVAL 581
AS ST F L+ L AAV L Y V + S CG F T Y A V L A
Sbjct: 645 ASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAA 704
Query: 582 G-----LPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQV 636
G LP + + + + + F F + +L V+ + + + + I L++Q+ +
Sbjct: 705 GPRVSWLPWVHR---YLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEG 761
Query: 637 QEKWHLVEDL 646
++K L+ L
Sbjct: 762 EDKIFLINKL 771
>gi|187608791 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 171 bits (434), Expect = 2e-42
Identities = 190/670 (28%), Positives = 293/670 (43%), Gaps = 122/670 (18%)
Query: 36 VRGLPYAMMDKRLIWQLREPAGVQTLRWQRWQRRRQTVE--RRLREAAQRLARGLGL--- 90
+RG+P ++ +KR LRE + +W+ RLR A LGL
Sbjct: 165 LRGMPLSLAEKR---SLREKSRTPRGKWRGQPGSGGVCSCCGRLRYACVLALHSLGLALL 221
Query: 91 --------WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPD 142
W AL IGG FG+ + SYF FL+ LL N L LLL +F++ P V P
Sbjct: 222 SALQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPAL 281
Query: 143 PGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRA-FTNTYLFYGAY------------ 189
PGP C G +LTG FT+T ++YG Y
Sbjct: 282 PGPAP----VCTGLE---------------LLTGAGCFTHTVMYYGHYSNATLNQPCGSP 322
Query: 190 --------RVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAP 241
RVG Y++ LAYL S + C TL V + G+ Y+
Sbjct: 323 LDGSQCTPRVG---GLPYNMPLAYL-STVGVSFFITCITL---VYSMAHS--FGESYRVG 373
Query: 242 LSA-----KVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRL 296
++ VF SWD+ + + A+ +++ I K L E Q + ++ C
Sbjct: 374 STSGIHAITVFCSWDYKVTQKRASRLQQDNIRTRLKELLAE------WQLRHSPRSVCGR 427
Query: 297 LSYLRVNVLNGLLVVG-----AISAIFWATKYSQDNK---EESLFLLLQYLPPGVIALVN 348
L V L LL +G A++ ++ Q + +E++ L+L P V+ L+N
Sbjct: 428 LRQAAVLGLVWLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVL----PLVVGLLN 483
Query: 349 FLGPLLFTFLVQLENYP-PNTEVNLTLIWCVVLKLASLGMFSVS-LGQTILCIGRDKSSC 406
P L L LE + P EV + + ++LKLA LG LG+ +
Sbjct: 484 LGAPYLCRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYHWLGRRV---------- 533
Query: 407 ESYGYNVCDYQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLER 466
V QCWE+ VG+ELY+ + +F+L + L R++ ++ R +
Sbjct: 534 -----GVLQGQCWEDFVGQELYRFLVMDFVLMLLDTLFGELVWRIISEKKLKR----RRK 584
Query: 467 EEFLVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFR 526
EF + +NVL+++ GQT+TW+G+ + PLLP + + L L FY+KK +LL N +A RP+
Sbjct: 585 PEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWL 644
Query: 527 AS-SSTFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLF----TNYSAPWQVVPELVAL 581
AS ST F L+ L AAV L Y V + S CG F T Y A V L A
Sbjct: 645 ASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAA 704
Query: 582 G-----LPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQV 636
G LP + + + + + F F + +L V+ + + + + I L++Q+ +
Sbjct: 705 GPRVSWLPWVHR---YLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISNEG 761
Query: 637 QEKWHLVEDL 646
++K L+ L
Sbjct: 762 EDKIFLINKL 771
>gi|94536852 transmembrane cochlear-expressed protein 2 [Homo
sapiens]
Length = 906
Score = 154 bits (388), Expect = 4e-37
Identities = 147/587 (25%), Positives = 256/587 (43%), Gaps = 53/587 (9%)
Query: 91 WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPTLNLT 150
WE + +I FG+ + SYF FLR++ +NL+ L V++P V + P
Sbjct: 234 WEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSIPRKTV 293
Query: 151 LQCPGSRQSPPGVL-RFHNQLWHVLTGRAFTNTYLFYGAYRVGPESSSV-YSIRLAYLLS 208
+ + VL F + + + LFYG Y + Y + +AY +
Sbjct: 294 PRAEEEKAMDFSVLWDFEGYIKY---------SALFYGYYNNQRTIGWLRYRLPMAYFMV 344
Query: 209 PLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEIS 268
++ +R M T G+ S K+F+SWD+ I E A K I+
Sbjct: 345 GVSVFGYSLIIVIRSMASNTQGSTGEGESDNFTFSFKMFTSWDYLIGNSETADNKYASIT 404
Query: 269 NEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRV--NVLNGLLVVGAISAIFWATKYSQD 326
FK + + +Q++ + L +LRV N L + G+ I++ K SQ
Sbjct: 405 TSFKESIVD-------EQESNKEENIHLTRFLRVLANFLIICCLCGSGYLIYFVVKRSQQ 457
Query: 327 -NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASL 385
+K +++ + V++L+ P LF + LENY P T + L L L +L
Sbjct: 458 FSKMQNVSWYERNEVEIVMSLLGMFCPPLFETIAALENYHPRTGLKWQLGRIFALFLGNL 517
Query: 386 GMFSVSLGQTI-LCIGRDKSSCESYGYNVCDY-----------------------QCWEN 421
F ++L + L + +++ + + +Y CWE
Sbjct: 518 YTFLLALMDDVHLKLANEETIKNITHWTLFNYYNSSGWNESVPRPPLHPADVPRGSCWET 577
Query: 422 SVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAW-LER-----EEFLVPKNV 475
+VG E +L++ + L+T L R V RF W W LE EF + NV
Sbjct: 578 AVGIEFMRLTVSDMLVTYITILLGDFLRACFV-RFMNYCWCWDLEAGFPSYAEFDISGNV 636
Query: 476 LDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQ 535
L ++ Q + WMG FY P L +N + L + Y + + ++ ++ R F+AS S F+
Sbjct: 637 LGLIFNQGMIWMGSFYAPGLVGINVLRLLTSMYFQCWAVMSSNVPHERVFKASRSNNFYM 696
Query: 536 LVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLG 595
+LLL L L+ +P+ Y + S+ S+DCG F+ + + V+ E + P + +L
Sbjct: 697 GLLLLVLFLSLLPVAYTIMSLPPSFDCGPFSGKNRMYDVLQETIENDFPTFLGKIFAFLA 756
Query: 596 SHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQL-VWQVQEKWH 641
+ P ++++ L + S +++ +RA +LRK++ V + EK H
Sbjct: 757 NPGLIIPAILLMFLAIYYLNSVSKSLSRANAQLRKKIQVLREVEKSH 803
>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
Length = 760
Score = 152 bits (383), Expect = 1e-36
Identities = 152/589 (25%), Positives = 256/589 (43%), Gaps = 59/589 (10%)
Query: 91 WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLP-LVWLRPPDPGPTLNL 149
WE + I FG+ + SYF FLR++ +N++ +LT S ++LP +W P P +
Sbjct: 170 WENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTV 229
Query: 150 TLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAYRVGPESSSV-YSIRLAYLLS 208
+ + + GVL N L + LFYG Y + + + L+Y L
Sbjct: 230 P-RAEEASAANFGVLYDFNGLAQY--------SVLFYGYYDNKRTIGWMNFRLPLSYFLV 280
Query: 209 PLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEIS 268
+ C+ F L+ M K + G S KVF+SWD+ I E A K + I+
Sbjct: 281 GIMCIGYSFLVVLKAMTKNIGDDGG-GDDNTFNFSWKVFTSWDYLIGNPETADNKFNSIT 339
Query: 269 NEFKVELEEGRRFQLMQQQTRAQTACRLLSYLR--VNVLNGLLVVGAISAIFWATKYSQD 326
FK + E + Q+ + L+ +LR N L + G+ IFWA K SQ+
Sbjct: 340 MNFKEAITEEKAAQVEEN-------VHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQE 392
Query: 327 NKEESLFLLLQYLPPGVIALVNFLG---PLLFTFLVQLENYPPNTEVNLTLIWCVVLKLA 383
++ L + + +++ LG P LF +LE+Y P + L L L
Sbjct: 393 FAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLG 452
Query: 384 SLGMFSVSLGQ----------------TILCIGRDKSSCESYGYN------------VCD 415
+L +F ++L T+ K+ S+ N V
Sbjct: 453 NLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPR 512
Query: 416 YQCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAW-LER-----EEF 469
CWE VG+E +L++ + L T + R V RF W W LE EF
Sbjct: 513 GPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFV-RFCNYCWCWDLEYGYPSYTEF 571
Query: 470 LVPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASS 529
+ NVL ++ Q + WMG F+ P LP +N + L + Y + + ++ + +R F+AS
Sbjct: 572 DISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASR 631
Query: 530 STFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQR 589
S F+ +LLL L L+ +P+ Y++ S+ S+DCG F+ + ++V+ E + P +
Sbjct: 632 SNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAK 691
Query: 590 ALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQE 638
L L + +++++ L + + + A L+K++ Q E
Sbjct: 692 ILRQLSNPGLVIAVILVMVLAIYYLNATAKGQKAANLDLKKKMKMQALE 740
>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
Length = 1100
Score = 108 bits (271), Expect = 1e-23
Identities = 66/222 (29%), Positives = 109/222 (49%), Gaps = 7/222 (3%)
Query: 417 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAW------LEREEFL 470
QCWE VG+E+ KLSI + L TVA L+ R L V R+ +W W E EF
Sbjct: 498 QCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFV-RYLSDYWCWDLESKFPEYGEFK 556
Query: 471 VPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSS 530
+ +NVL +V Q + WMG F+ P LP N + L Y++ + +L + + FRAS S
Sbjct: 557 IAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRS 616
Query: 531 TFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRA 590
F+ +LL L L +P + + S +CG F+ + +V E + P
Sbjct: 617 NNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSV 676
Query: 591 LHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQL 632
+ ++ S P +++L +++ S ++ + H+L+ Q+
Sbjct: 677 VGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQI 718
Score = 90.5 bits (223), Expect = 5e-18
Identities = 84/306 (27%), Positives = 140/306 (45%), Gaps = 18/306 (5%)
Query: 91 WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPTLNLT 150
WE + +I FG+G+ SYF FLR+L +N++ ++T +F+++P + P G T T
Sbjct: 123 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPF-GSTARKT 181
Query: 151 LQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAY-RVGPESSSVYSIRLAYLLSP 209
+ P + S L + +W + G + LFYG Y R + Y + LAY L
Sbjct: 182 I--PKEQVSSAQDL---DTVWSL--GGYLQYSVLFYGYYGRERKIGRAGYRLPLAYFLVG 234
Query: 210 LACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISN 269
+A F L++M K +VF +WD+ I EAA K I N
Sbjct: 235 MAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVN 294
Query: 270 EFKVELEEGRRFQLMQQQTRAQTAC-RLLSYLRVNVLNGLLVVGAISAIFWATKYSQ--D 326
+ + E + + + + A T C R+++ N+L L + G+I I++ SQ +
Sbjct: 295 SIREAILEEQ--EKKKSKNLAVTICLRIIA----NILVLLSLAGSIYLIYFVVDRSQKLE 348
Query: 327 NKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASLG 386
++ L L + V++LV + P F + LE Y P T + L +VL L +L
Sbjct: 349 QSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVLYLGNLY 408
Query: 387 MFSVSL 392
++L
Sbjct: 409 SLIIAL 414
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 40.0 bits (92), Expect = 0.008
Identities = 26/66 (39%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP----CPGQ 708
PGP +PGP PA + P PG PG + P PGPS+ G R P PG
Sbjct: 832 PGPPGAPGPAGPAGLPGHQEVLNLQGP-PGPPGPRGP-PGPSIPGPPGPRGPPGEGLPGP 889
Query: 709 HGAPAS 714
G P S
Sbjct: 890 PGPPGS 895
Score = 31.2 bits (69), Expect = 3.5
Identities = 22/71 (30%), Positives = 25/71 (35%), Gaps = 12/71 (16%)
Query: 653 PGPSDSPGPKYPASQASRP----------QSFCPGCPCPGSP-GHQAPRPGPSVVDAAGL 701
PGP G K P P + G P P GHQ PR + G+
Sbjct: 706 PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGI 765
Query: 702 RSPCPGQHGAP 712
R P PG G P
Sbjct: 766 RGP-PGPSGDP 775
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 39.3 bits (90), Expect = 0.013
Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 2/65 (3%)
Query: 651 PEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHG 710
P P P P P A+ A P++ P SPG +PGP AA L +P P
Sbjct: 129 PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPG--PAQPGPRAQRAAPLAAPPPAPAA 186
Query: 711 APASA 715
PA A
Sbjct: 187 PPAVA 191
Score = 30.0 bits (66), Expect = 7.9
Identities = 14/36 (38%), Positives = 16/36 (44%)
Query: 658 SPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGP 693
SPGP P +A R P P +P AP GP
Sbjct: 161 SPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGP 196
>gi|56606142 complement component 1, q subcomponent-like 4 [Homo
sapiens]
Length = 238
Score = 38.9 bits (89), Expect = 0.017
Identities = 25/56 (44%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 654 GPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPG--PSVVDAAGLRSPCPG 707
GP PGP+ P + RP PG P PG PG AP G P + AGLR P G
Sbjct: 70 GPPGPPGPRGPPGEPGRPGP--PGPPGPG-PGGVAPAAGYVPRIAFYAGLRRPHEG 122
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 38.1 bits (87), Expect = 0.029
Identities = 29/74 (39%), Positives = 32/74 (43%), Gaps = 9/74 (12%)
Query: 650 LPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSV-VDAAGLRSPCPGQ 708
LP P P PGP + A PQ PG P SP RP P + V G P G
Sbjct: 2175 LPPPAP---PGPSFLLPLAPGPQLLNPGTPV--SPQE---RPPPYLAVPGHGEEYPAAGA 2226
Query: 709 HGAPASARRFRFPS 722
H +P AR R PS
Sbjct: 2227 HSSPPKARFLRVPS 2240
Score = 33.1 bits (74), Expect = 0.93
Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 11/80 (13%)
Query: 637 QEKWHLVEDLSRLLPEP-GPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRP---- 691
QE+ H +D+ RLL +P GP PGP P +F PG S ++ RP
Sbjct: 2013 QERLH--QDIVRLLDQPSGPRSPPGPHGLGPLLCPPGAFLPGLKAAQSGSKKSRRPPGKA 2070
Query: 692 --GPSVVDAAG--LRSPCPG 707
GP G L CPG
Sbjct: 2071 GLGPQGPRGRGKKLTLACPG 2090
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 37.7 bits (86), Expect = 0.038
Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 8/63 (12%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP 712
PGP+ PGP P + P S PGSPG+Q P P +G P PG G
Sbjct: 173 PGPAGPPGPPGPPGTSGHPGS-------PGSPGYQGPPGEPGQAGPSGPPGP-PGAIGPS 224
Query: 713 ASA 715
A
Sbjct: 225 GPA 227
Score = 37.7 bits (86), Expect = 0.038
Identities = 32/81 (39%), Positives = 34/81 (41%), Gaps = 23/81 (28%)
Query: 653 PGPSDSPG---PKYPASQASRPQSFCPGCPCP----------GSPGHQAP--RPGP---- 693
PGPS SPG P PA P S PG P GSPG Q P PGP
Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGS--PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIA 950
Query: 694 SVVDAAGLRSP--CPGQHGAP 712
+ A GL P PG G+P
Sbjct: 951 GITGARGLAGPPGMPGPRGSP 971
Score = 30.8 bits (68), Expect = 4.6
Identities = 27/76 (35%), Positives = 32/76 (42%), Gaps = 17/76 (22%)
Query: 652 EPGPSDSPGPK-------YPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGL--- 701
EPG +PG P + R ++ PG P G+PGH P PGP V AG
Sbjct: 1009 EPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAP--GAPGHPGP-PGP--VGPAGKSGD 1063
Query: 702 --RSPCPGQHGAPASA 715
S G GAP A
Sbjct: 1064 RGESGPAGPAGAPGPA 1079
Score = 30.4 bits (67), Expect = 6.1
Identities = 20/61 (32%), Positives = 22/61 (36%), Gaps = 8/61 (13%)
Query: 654 GPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPA 713
GP+ PG K PA + G P P P A PG V PG G P
Sbjct: 495 GPNGIPGEKGPAGER--------GAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPG 546
Query: 714 S 714
S
Sbjct: 547 S 547
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 8/62 (12%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP 712
PGP SPGP+ ++ +P + G G + P PGP + + PG+ G P
Sbjct: 965 PGPRGSPGPQGVKGESGKPGA-------NGLSGERGP-PGPQGLPGLAGTAGEPGRDGNP 1016
Query: 713 AS 714
S
Sbjct: 1017 GS 1018
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 37.4 bits (85), Expect = 0.050
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 9/72 (12%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPC-PGSPGHQAPRPGPSVVDAAGLRS-PCP---- 706
PGP GP + + PG P PGSPG Q PR P + G R P P
Sbjct: 1432 PGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEA 1491
Query: 707 ---GQHGAPASA 715
G+ G P A
Sbjct: 1492 GEKGERGPPGPA 1503
Score = 33.5 bits (75), Expect = 0.71
Identities = 22/64 (34%), Positives = 26/64 (40%), Gaps = 2/64 (3%)
Query: 652 EPGPSDSPGPKYP-ASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHG 710
+PGPS PGP+ P R PG G G + R GP G+ PG G
Sbjct: 1369 DPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGER-GPPGPGEGGIAPGEPGLPG 1427
Query: 711 APAS 714
P S
Sbjct: 1428 LPGS 1431
Score = 30.4 bits (67), Expect = 6.1
Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 8/75 (10%)
Query: 653 PGPSDSPGPK-YPASQASRPQSFCPGCP-CPGSPGHQAPRPGPSVVDAAGLR-SP-CPGQ 708
PG + +PGP+ P S ++ + PG PGSPG P A GL+ SP PG
Sbjct: 1277 PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAG---NPGTPGAPGLKGSPGLPGP 1333
Query: 709 HGAPASARRFRFPSG 723
G P R R P G
Sbjct: 1334 RGDPGE-RGPRGPKG 1347
Score = 30.0 bits (66), Expect = 7.9
Identities = 25/72 (34%), Positives = 28/72 (38%), Gaps = 9/72 (12%)
Query: 652 EPGPSDSPGPKYP---ASQASRPQSFCP----GCP-CPGSPGHQAPRPGPSVVDAAGLRS 703
+PGP PG + P +A P P G P PG PG PR V G
Sbjct: 1584 DPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEG 1643
Query: 704 PCPGQHGAPASA 715
P PG G P A
Sbjct: 1644 P-PGDPGLPGKA 1654
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 36.6 bits (83), Expect = 0.084
Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 2/64 (3%)
Query: 651 PEPGPSDSPGPKYPASQASRPQSFCP-GCPCPGSPGHQAPRPGPSVVDAAGLRS-PCPGQ 708
PEPG D PG A + + P G P P SPG P PG + A + P PG
Sbjct: 19 PEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDEPAPGAAADGGARWSAGPAPGL 78
Query: 709 HGAP 712
G P
Sbjct: 79 EGGP 82
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 36.6 bits (83), Expect = 0.084
Identities = 28/71 (39%), Positives = 28/71 (39%), Gaps = 10/71 (14%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP 712
PGP S GP PA R P PG PG Q P PGP G R PG G P
Sbjct: 1232 PGPPGSSGPPGPAGATGRAPK---DIPDPGPPGDQGP-PGPD-----GPRG-APGPPGLP 1281
Query: 713 ASARRFRFPSG 723
S R G
Sbjct: 1282 GSVDLLRGEPG 1292
Score = 35.4 bits (80), Expect = 0.19
Identities = 24/69 (34%), Positives = 24/69 (34%), Gaps = 23/69 (33%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPC-------PGSPGHQAPRPGPSVVDAAGLRSP- 704
PGP PG PGCP G PG Q PR P G P
Sbjct: 1084 PGPKGEPGS--------------PGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPP 1129
Query: 705 -CPGQHGAP 712
CPG HG P
Sbjct: 1130 GCPGDHGMP 1138
Score = 31.2 bits (69), Expect = 3.5
Identities = 24/65 (36%), Positives = 27/65 (41%), Gaps = 18/65 (27%)
Query: 652 EPGPSDSPGPK-YPASQASRPQSFCPGC----PCPGSPGHQAPRPGPSVVDAAGLRSPCP 706
EPGP PGP P Q S+ PG PG PG + P PG P
Sbjct: 495 EPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGP-PG------------LP 541
Query: 707 GQHGA 711
G+HGA
Sbjct: 542 GKHGA 546
Score = 30.0 bits (66), Expect = 7.9
Identities = 22/71 (30%), Positives = 26/71 (36%), Gaps = 9/71 (12%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP 712
PGP PGP P P C G G + P P G P PG+ G P
Sbjct: 1297 PGPPGPPGPPGPPGYKGFP-------GCDGKDGQKGPVGFPGPQGPHGFPGP-PGEKGLP 1348
Query: 713 ASARRFRFPSG 723
R + P+G
Sbjct: 1349 GPPGR-KGPTG 1358
>gi|195972903 zinc finger protein 385A isoform a [Homo sapiens]
Length = 386
Score = 36.6 bits (83), Expect = 0.084
Identities = 45/164 (27%), Positives = 64/164 (39%), Gaps = 32/164 (19%)
Query: 563 GLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANA 622
GLF+NYS + P+ + L SH F PLL V++ + Q + N+
Sbjct: 42 GLFSNYST------------MDPVQKAVL----SHTFGGPLLKTKRPVISCNICQIRFNS 85
Query: 623 RA---IHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPASQ-------ASRPQ 672
++ H + +V+ +E EPG + P P S A RP
Sbjct: 86 QSQAEAHYKGNRHARRVKG----IEAAKTRGREPGVREPGDPAPPGSTPTNGDGVAPRPV 141
Query: 673 SFCPGC-PCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASA 715
S G P PGSP Q P P + G + G+ G PA A
Sbjct: 142 SMENGLGPAPGSPEKQPGSPSPPSIPETG-QGVTKGEGGTPAPA 184
>gi|24308079 zinc finger protein 385A isoform c [Homo sapiens]
Length = 366
Score = 36.6 bits (83), Expect = 0.084
Identities = 45/164 (27%), Positives = 64/164 (39%), Gaps = 32/164 (19%)
Query: 563 GLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANA 622
GLF+NYS + P+ + L SH F PLL V++ + Q + N+
Sbjct: 22 GLFSNYST------------MDPVQKAVL----SHTFGGPLLKTKRPVISCNICQIRFNS 65
Query: 623 RA---IHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPASQ-------ASRPQ 672
++ H + +V+ +E EPG + P P S A RP
Sbjct: 66 QSQAEAHYKGNRHARRVKG----IEAAKTRGREPGVREPGDPAPPGSTPTNGDGVAPRPV 121
Query: 673 SFCPGC-PCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASA 715
S G P PGSP Q P P + G + G+ G PA A
Sbjct: 122 SMENGLGPAPGSPEKQPGSPSPPSIPETG-QGVTKGEGGTPAPA 164
>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
Length = 703
Score = 36.2 bits (82), Expect = 0.11
Identities = 27/65 (41%), Positives = 29/65 (44%), Gaps = 9/65 (13%)
Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPG-HQAPRP-GPSVVDAAGLRSP--CPG 707
EPGP PGP+ P P F PG P G PG H P P GP G P PG
Sbjct: 78 EPGPPGKPGPRGPPG----PPGF-PGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPG 132
Query: 708 QHGAP 712
+ G P
Sbjct: 133 KVGPP 137
Score = 35.8 bits (81), Expect = 0.14
Identities = 29/83 (34%), Positives = 36/83 (43%), Gaps = 19/83 (22%)
Query: 653 PGPSDSPGPK---------YPASQASRPQSFCPGCPCP-GSPGHQAPRPGPSVVDAAGLR 702
PGP PGP P + + +S PG P P G PG P+ GP VD G+
Sbjct: 225 PGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPK-GPPGVDGVGV- 282
Query: 703 SPCPGQHGAPASARRFRFPSGAE 725
PG G P + PSGA+
Sbjct: 283 ---PGAAGLPGP----QGPSGAK 298
Score = 33.1 bits (74), Expect = 0.93
Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 2/62 (3%)
Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCPCP-GSPGHQAPRPGPSVVDAAGLRSPCPGQHG 710
+PG PGP P + ++ PG P G PG R P + GLR P PG G
Sbjct: 104 KPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGP-PGPPG 162
Query: 711 AP 712
P
Sbjct: 163 LP 164
Score = 31.6 bits (70), Expect = 2.7
Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP-CPGQHG 710
EPGP PGP P + + + PG+PG P + AGL P G G
Sbjct: 189 EPGPQGEPGP--PGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPG 246
Query: 711 AP 712
AP
Sbjct: 247 AP 248
Score = 30.8 bits (68), Expect = 4.6
Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 13/70 (18%)
Query: 654 GPSDSPGPKYPASQASRPQSFC-----PGCPCP------GSPGHQAPRPGPSVVDAAGLR 702
GPS PG + PA PQ PG P P G PG P P V + G+
Sbjct: 460 GPSGIPGLQGPAGPIG-PQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGIT 518
Query: 703 SPCPGQHGAP 712
P PG G P
Sbjct: 519 GP-PGPPGPP 527
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 36.2 bits (82), Expect = 0.11
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 12/67 (17%)
Query: 654 GPSDSPGPKYPASQASRPQSFCPGCPCP-------GSPGHQAP--RPG---PSVVDAAGL 701
GP PGP P+ ++ PG P P G PG Q P +PG PS A G+
Sbjct: 1710 GPRGPPGPAGPSGESRPGSPGPPGSPGPRGPPGHLGVPGPQGPSGQPGYCDPSSCSAYGV 1769
Query: 702 RSPCPGQ 708
R+P P Q
Sbjct: 1770 RAPHPDQ 1776
Score = 31.2 bits (69), Expect = 3.5
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 2/61 (3%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPC-PGSPGHQAPRPGPSVVDAAGLRSPCPGQHGA 711
PGP PGP+ P+ + + PG G G P+ P V + G R PGQ G
Sbjct: 1497 PGPQGPPGPQGPSGLSIQGMPGMPGEKGEKGDTGLPGPQGIPGGVGSPG-RDGSPGQRGL 1555
Query: 712 P 712
P
Sbjct: 1556 P 1556
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 35.8 bits (81), Expect = 0.14
Identities = 21/71 (29%), Positives = 26/71 (36%)
Query: 651 PEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHG 710
P P P P P Q+ PQ P PCP ++P RSP P
Sbjct: 348 PSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQ 407
Query: 711 APASARRFRFP 721
+P+ RR P
Sbjct: 408 SPSPQRRSPVP 418
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 35.4 bits (80), Expect = 0.19
Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 12/82 (14%)
Query: 643 VEDLSRLLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLR 702
+ S P P+DSP P+ + + S P S G AP P P VV A +R
Sbjct: 345 IASASTTAPASSPADSPRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIR 404
Query: 703 ------------SPCPGQHGAP 712
SP PG + +P
Sbjct: 405 PSVYQPVPASTYSPSPGANYSP 426
Score = 30.8 bits (68), Expect = 4.6
Identities = 27/82 (32%), Positives = 31/82 (37%), Gaps = 16/82 (19%)
Query: 651 PEPGPSDSPGPKY-----PASQASRP---------QSFCPGCPCPGSPGHQAPRPGPSVV 696
P P P+ +P P PA ASRP Q F PG PR GP+
Sbjct: 463 PSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYT 522
Query: 697 DAAGLRSPCPGQHGAPASARRF 718
AG + P P G A RF
Sbjct: 523 -PAGPQVP-PLARGTVQRAERF 542
>gi|194294532 alpha 1 type XIII collagen isoform 20 [Homo sapiens]
Length = 717
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/64 (32%), Positives = 25/64 (39%), Gaps = 9/64 (14%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP-----CPG 707
PGP PGP P P P PG PG P+ P + G + PG
Sbjct: 272 PGPPGPPGPSGPLGHPGLPGPMGP----PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPG 327
Query: 708 QHGA 711
+HGA
Sbjct: 328 KHGA 331
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 5/46 (10%)
Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCP----CPGSPGHQAPRPGP 693
E G + SPG K A + P + PG P PG PG Q PGP
Sbjct: 543 ETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGV-PGP 587
Score = 30.0 bits (66), Expect = 7.9
Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 5/41 (12%)
Query: 676 PGCPCPGSPGHQAPRPG-PSVVDAAGLRSPCPGQHGAPASA 715
PGC CP P RPG P A G+ PG+ G+P A
Sbjct: 115 PGCNCPPGPPGPTGRPGLPGDKGAIGM----PGRVGSPGDA 151
>gi|22027609 alpha 1 type XIII collagen isoform 19 [Homo sapiens]
Length = 610
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/64 (32%), Positives = 25/64 (39%), Gaps = 9/64 (14%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP-----CPG 707
PGP PGP P P P PG PG P+ P + G + PG
Sbjct: 221 PGPPGPPGPSGPLGHPGLPGPMGP----PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPG 276
Query: 708 QHGA 711
+HGA
Sbjct: 277 KHGA 280
>gi|22027607 alpha 1 type XIII collagen isoform 18 [Homo sapiens]
Length = 655
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/64 (32%), Positives = 25/64 (39%), Gaps = 9/64 (14%)
Query: 653 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSP-----CPG 707
PGP PGP P P P PG PG P+ P + G + PG
Sbjct: 210 PGPPGPPGPSGPLGHPGLPGPMGP----PGLPGPPGPKGDPGIQGYHGRKGERGMPGMPG 265
Query: 708 QHGA 711
+HGA
Sbjct: 266 KHGA 269
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 5/46 (10%)
Query: 652 EPGPSDSPGPKYPASQASRPQSFCPGCP----CPGSPGHQAPRPGP 693
E G + SPG K A + P + PG P PG PG Q PGP
Sbjct: 481 ETGQAGSPGEKGEAGEKGNPGAEVPGLPGPEGPPGPPGLQGV-PGP 525
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,354,615
Number of Sequences: 37866
Number of extensions: 1680400
Number of successful extensions: 10574
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 238
Number of HSP's that attempted gapping in prelim test: 9353
Number of HSP's gapped (non-prelim): 1375
length of query: 726
length of database: 18,247,518
effective HSP length: 110
effective length of query: 616
effective length of database: 14,082,258
effective search space: 8674670928
effective search space used: 8674670928
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.