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Search of human proteins with 115529439
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
(491 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 1012 0.0
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 397 e-110
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 395 e-110
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 394 e-110
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 390 e-108
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 359 3e-99
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 355 7e-98
gi|33563374 carboxylesterase 3 [Homo sapiens] 337 1e-92
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 315 5e-86
gi|30840978 neuroligin 2 [Homo sapiens] 254 2e-67
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 251 1e-66
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 251 1e-66
gi|51593088 neuroligin 3 [Homo sapiens] 234 1e-61
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 231 1e-60
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 231 1e-60
gi|7662470 neuroligin 1 [Homo sapiens] 229 4e-60
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 227 2e-59
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 222 5e-58
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 199 5e-51
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 199 6e-51
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 197 2e-50
gi|55770862 thyroglobulin [Homo sapiens] 138 1e-32
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 113 3e-25
gi|224589077 hypothetical protein LOC285600 isoform 1 [Homo sapi... 33 0.45
gi|27734815 hypothetical protein LOC285600 isoform 2 [Homo sapiens] 33 0.45
gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] 33 0.77
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 32 1.0
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 32 1.7
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens] 30 5.0
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 1012 bits (2617), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 1 MRWILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPP 60
MRWILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPP
Sbjct: 1 MRWILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPP 60
Query: 61 LGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLN 120
LGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLN
Sbjct: 61 LGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLN 120
Query: 121 VYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLST 180
VYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLST
Sbjct: 121 VYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLST 180
Query: 181 DDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLF 240
DDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLF
Sbjct: 181 DDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLF 240
Query: 241 HRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKM 300
HRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKM
Sbjct: 241 HRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKM 300
Query: 301 RFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPY 360
RFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPY
Sbjct: 301 RFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPY 360
Query: 361 NITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRGLSMGKEKA 420
NITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRGLSMGKEKA
Sbjct: 361 NITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRGLSMGKEKA 420
Query: 421 LSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSLY 480
LSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSLY
Sbjct: 421 LSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSLY 480
Query: 481 QSQRPEKQRQF 491
QSQRPEKQRQF
Sbjct: 481 QSQRPEKQRQF 491
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 397 bits (1019), Expect = e-110
Identities = 223/557 (40%), Positives = 316/557 (56%), Gaps = 79/557 (14%)
Query: 11 LCLMAQTALGALHTKRPQVV-TKYGTLQGKQMHVG--KTPIQVFLGVPFSRPPLGILRFA 67
L ++ +A A H P VV T +G + GK + + P+ +FLG+PF++PPLG LRF
Sbjct: 8 LATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFT 67
Query: 68 PPEPPEPWKGIRDATTYPPGCLQE-SWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPAR 126
PP+P EPW +++AT+YPP C Q+ GQL S + R+ L+ SEDCLYLN+Y PA
Sbjct: 68 PPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPAD 127
Query: 127 APGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHAR 186
+LPVMVW GG +VGAAS+Y+G LAA E VV+V +Q+RLGI+GF ST D H+R
Sbjct: 128 LTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSR 187
Query: 187 GNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQ 246
GNWG LDQ+AALRWVQ+NIA+FGG+PG+VT+FG+SAG S+S L++SPLA LFHRAIS+
Sbjct: 188 GNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISE 247
Query: 247 SGTALFRLFITSNPLK-VAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQL 305
SG AL + + +K +A+++A AGC ++ ++V+CLR + +++ + KM+FL L
Sbjct: 248 SGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSL 307
Query: 306 NFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYN---- 361
+ Q DP E + V+DG+++ P L + +VPY++G+N EF WL+P
Sbjct: 308 DLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSY 367
Query: 362 ------------------------ITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDA 397
I KE +P E+YL + D ++ +D++ D
Sbjct: 368 PLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTD--DTVKKKDLFLDLIADV 425
Query: 398 TFVYATLQTAHYHR--------------------------------------GLSMGKEK 419
F ++ A HR G KE
Sbjct: 426 MFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEG 485
Query: 420 A------LSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKM 473
A LS +MK+WANFAR GNPN LP WP YN+ E YLQ+ T+ KLK+K++
Sbjct: 486 ASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEV 545
Query: 474 AFWMSLYQSQRPEKQRQ 490
AFW +L+ + EK Q
Sbjct: 546 AFWTNLFAKKAVEKPPQ 562
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 395 bits (1015), Expect = e-110
Identities = 226/565 (40%), Positives = 318/565 (56%), Gaps = 82/565 (14%)
Query: 3 WILCWSLTLCLMAQTALGALHTKRPQVV-TKYGTLQGKQMHVG--KTPIQVFLGVPFSRP 59
W+ + L L A A G H P VV T +G + GK + + P+ +FLG+PF++P
Sbjct: 2 WLRAFILAT-LSASAAWG--HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKP 58
Query: 60 PLGILRFAPPEPPEPWKGIRDATTYPPGCLQE-SWGQLASMYVSTRERYKWLRFSEDCLY 118
PLG LRF PP+P EPW +++AT+YPP C Q+ GQL S + R+ L+ SEDCLY
Sbjct: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY 118
Query: 119 LNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFL 178
LN+Y PA +LPVMVW GG +VGAAS+Y+G LAA E VV+V +Q+RLGI+GF
Sbjct: 119 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFF 178
Query: 179 STDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASG 238
ST D H+RGNWG LDQ+AALRWVQ+NIA+FGG+PG+VT+FG+SAG S+S L++SPLA
Sbjct: 179 STGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN 238
Query: 239 LFHRAISQSGTALFRLFITSNPLK-VAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVS 297
LFHRAIS+SG AL + + +K +A+++A AGC ++ ++V+CLR + +++ +
Sbjct: 239 LFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETT 298
Query: 298 NKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWL 357
KM+FL L+ Q DP E + V+DG+++ P L + +VPY++G+N EF WL
Sbjct: 299 LKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWL 358
Query: 358 LPYN----------------------------ITKEQVPLVVEEYLDNVNEHDWKMLRNR 389
+P I KE +P E+YL + D ++
Sbjct: 359 IPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTD--DTVKKKDL 416
Query: 390 MMDIVQDATFVYATLQTAHYHR-------------------------------------- 411
+D++ D F ++ A HR
Sbjct: 417 FLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVF 476
Query: 412 GLSMGKEKA------LSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVG 465
G KE A LS +MK+WANFAR GNPN LP WP YN+ E YLQ+ T+
Sbjct: 477 GAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAA 536
Query: 466 MKLKEKKMAFWMSLYQSQRPEKQRQ 490
KLK+K++AFW +L+ + EK Q
Sbjct: 537 QKLKDKEVAFWTNLFAKKAVEKPPQ 561
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 394 bits (1013), Expect = e-110
Identities = 226/564 (40%), Positives = 318/564 (56%), Gaps = 81/564 (14%)
Query: 3 WILCWSLTLCLMAQTALGALHTKRPQVV-TKYGTLQGKQMHVG--KTPIQVFLGVPFSRP 59
W+ + L L A A G H P VV T +G + GK + + P+ +FLG+PF++P
Sbjct: 2 WLRAFILAT-LSASAAWG--HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKP 58
Query: 60 PLGILRFAPPEPPEPWKGIRDATTYPPGCLQE-SWGQLASMYVSTRERYKWLRFSEDCLY 118
PLG LRF PP+P EPW +++AT+YPP C Q+ GQL S + R+ L+ SEDCLY
Sbjct: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY 118
Query: 119 LNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFL 178
LN+Y PA +LPVMVW GG +VGAAS+Y+G LAA E VV+V +Q+RLGI+GF
Sbjct: 119 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFF 178
Query: 179 STDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASG 238
ST D H+RGNWG LDQ+AALRWVQ+NIA+FGG+PG+VT+FG+SAG S+S L++SPLA
Sbjct: 179 STGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN 238
Query: 239 LFHRAISQSGTALFRLFITSNPLK-VAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVS 297
LFHRAIS+SG AL + + +K +A+++A AGC ++ ++V+CLR + +++ +
Sbjct: 239 LFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETT 298
Query: 298 NKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWL 357
KM+FL L+ Q DP E + V+DG+++ P L + +VPY++G+N EF WL
Sbjct: 299 LKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWL 358
Query: 358 LP---------------------------YNITKEQVPLVVEEYLDNVNEHDWKMLRNRM 390
+P I KE +P E+YL + D ++
Sbjct: 359 IPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTD--DTVKKKDLF 416
Query: 391 MDIVQDATFVYATLQTAHYHR--------------------------------------G 412
+D++ D F ++ A HR G
Sbjct: 417 LDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFG 476
Query: 413 LSMGKEKA------LSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGM 466
KE A LS +MK+WANFAR GNPN LP WP YN+ E YLQ+ T+
Sbjct: 477 APFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQ 536
Query: 467 KLKEKKMAFWMSLYQSQRPEKQRQ 490
KLK+K++AFW +L+ + EK Q
Sbjct: 537 KLKDKEVAFWTNLFAKKAVEKPPQ 560
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 390 bits (1001), Expect = e-108
Identities = 214/482 (44%), Positives = 290/482 (60%), Gaps = 51/482 (10%)
Query: 27 PQVVTKYGTLQGKQMHV--GKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTY 84
PQ T+ G +QGKQ+ V P+ VFLGVPF+ PPLG LRF P+P PW +R+AT+Y
Sbjct: 31 PQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSY 90
Query: 85 PPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAF 144
P CLQ S L ++ + Y SEDCLYLN+YAPA A +LPV+VWFPGGAF
Sbjct: 91 PNLCLQNSEWLLLDQHM-LKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAF 149
Query: 145 IVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQEN 204
G+AS ++GS LAA E V++V +Q+RLGIFGF +T D HA GNW DQ+AAL WVQ+N
Sbjct: 150 KTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKN 209
Query: 205 IAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRL-----FITSN 259
I FGGDP +VT+FG+SAGA+S+S L++SP+A GLFH+AI +SG A+ + S
Sbjct: 210 IEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSE 269
Query: 260 PLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMS 319
L+V VAH G N + ++ L+ CLR +++ +S K + S +
Sbjct: 270 DLQV---VAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTK---------------SFT 311
Query: 320 PVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP-------------------- 359
VVDG P++PL LL+Q ++P ++GVNN E +LLP
Sbjct: 312 RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLI 371
Query: 360 ---YNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRGLSMG 416
+I + + LV EY ++H +R+ ++D++ D FV L TA YHR +
Sbjct: 372 QNILHIPPQYLHLVANEYFH--DKHSLTEIRDSLLDLLGDVFFVVPALITARYHREGATE 429
Query: 417 KEKALSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFW 476
+EK LS +MMKYWA FARTGNPN +L WP YN E+YLQLD +G +LKE ++ FW
Sbjct: 430 EEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFW 489
Query: 477 MS 478
S
Sbjct: 490 TS 491
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 359 bits (922), Expect = 3e-99
Identities = 205/525 (39%), Positives = 285/525 (54%), Gaps = 80/525 (15%)
Query: 27 PQVVTKYGTLQGKQMHV--GKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTY 84
P T G + G +HV +Q FLG+PF++PPLG LRFAPPEPPE W G+RD TT+
Sbjct: 96 PIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTH 155
Query: 85 PPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAF 144
P CLQ+ + + SEDCLYL++Y PA + LPVMVW GGA
Sbjct: 156 PAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGAL 215
Query: 145 IVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQEN 204
+ G AS Y+GS LAA E VV+V +Q+RLG+ GF ST D HA GNWG LDQ+AALRWVQ+N
Sbjct: 216 VFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQN 275
Query: 205 IAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVA 264
IA FGG+P VT+FG+SAG S+S L++SP++ GLFH AI +SG AL I S+ ++
Sbjct: 276 IAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVIS 335
Query: 265 KKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDG 324
VA+L+ C+ ++ LV CLR S +++ ++ + + VVDG
Sbjct: 336 TVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMI---------------PGVVDG 380
Query: 325 VVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP-----YNITKE-------------- 365
V +P P LL VP ++GVNN EF WL+P Y+ KE
Sbjct: 381 VFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKML 440
Query: 366 ---QVP-----LVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRGLS--- 414
+P L+ EEY+ + D + L+ + +++ D+ FV LQ AH+ +
Sbjct: 441 TLLMLPPTFGDLLREEYIG--DNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVY 498
Query: 415 --------------------------MGKEKALSLQMMKYWANFARTGNPNDGNLPCWPR 448
+E+ LS +MMKYWANFAR GNPN LP WP
Sbjct: 499 FYEFQHQPSWLKNIRPPHMKADHVKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPHWPL 558
Query: 449 YNKDEKYLQLDFTTRVGMKLKEKKMAFW-----MSLYQSQRPEKQ 488
++++E+YLQL+ VG LK ++ FW + + + PE++
Sbjct: 559 FDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEER 603
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 355 bits (910), Expect = 7e-98
Identities = 207/541 (38%), Positives = 286/541 (52%), Gaps = 96/541 (17%)
Query: 27 PQVVTKYGTLQGKQMHV--GKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTY 84
P T G + G +HV +Q FLG+PF++PPLG LRFAPPEPPE W G+RD TT+
Sbjct: 96 PIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTH 155
Query: 85 PPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAF 144
P CLQ+ + + SEDCLYL++Y PA + LPVMVW GGA
Sbjct: 156 PAMCLQDLTAVESEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGAL 215
Query: 145 IVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQEN 204
+ G AS Y+GS LAA E VV+V +Q+RLG+ GF ST D HA GNWG LDQ+AALRWVQ+N
Sbjct: 216 VFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQN 275
Query: 205 IAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVA 264
IA FGG+P VT+FG+SAG S+S L++SP++ GLFH AI +SG AL I S+ ++
Sbjct: 276 IAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVIS 335
Query: 265 KKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDG 324
VA+L+ C+ ++ LV CLR S +++ ++ + + VVDG
Sbjct: 336 TVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMI---------------PGVVDG 380
Query: 325 VVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP-----YNITKE-------------- 365
V +P P LL VP ++GVNN EF WL+P Y+ KE
Sbjct: 381 VFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKML 440
Query: 366 ---QVP-----LVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHY-------- 409
+P L+ EEY+ + D + L+ + +++ D+ FV LQ AH+
Sbjct: 441 TLLMLPPTFGDLLREEYIG--DNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVY 498
Query: 410 -----------------HRGLSMG--------------------KEKALSLQMMKYWANF 432
H G +E+ LS +MMKYWANF
Sbjct: 499 FYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANF 558
Query: 433 ARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFW-----MSLYQSQRPEK 487
AR GNPN LP WP ++++E+YLQL+ VG LK ++ FW + + + PE+
Sbjct: 559 ARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKIQELEEPEE 618
Query: 488 Q 488
+
Sbjct: 619 R 619
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 337 bits (865), Expect = 1e-92
Identities = 206/539 (38%), Positives = 287/539 (53%), Gaps = 98/539 (18%)
Query: 26 RPQVVTKYGTLQGKQMHVGKTP--IQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATT 83
+P+V T G ++G+Q+ V T + VFLG+PF++PPLG RF+ P P +PW+G+RDA+T
Sbjct: 33 QPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDAST 92
Query: 84 YPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGA 143
PP CLQ+ +S +V ++ + SEDCL LNVY+PA P PVMVW GGA
Sbjct: 93 APPMCLQDVESMNSSRFVLNGKQ-QIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGA 151
Query: 144 FIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQE 203
I GAA+SY+GS LAA VV+V +Q+RLG+ GF ST D HA GN G LD +AALRWVQE
Sbjct: 152 LITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQE 211
Query: 204 NIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKV 263
NIA FGGD VT+FG SAG ISGL++SP+A+GLFHRAI+QSG I S+P +
Sbjct: 212 NIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPL 271
Query: 264 AKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVD 323
A+K+A+ C+ +S +V CL+ G +++ +S K++ I+ ++ VD
Sbjct: 272 AQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLK-----------NTIYPLT--VD 317
Query: 324 GVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP------------------------ 359
G V P P LL + SVP+L+GVNN EF+WL+P
Sbjct: 318 GTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPV 377
Query: 360 ---YNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHY------- 409
++ E +P V++EYL + ++ K + + D T+ + Y
Sbjct: 378 LTSLDVPPEMMPTVIDEYLGSNSDAQAKC--QAFQEFMGDVFINVPTVSFSRYLRDSGSP 435
Query: 410 -------HRGLSMGK--------------------------------------EKALSLQ 424
HR S K EK LSL
Sbjct: 436 VFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLT 495
Query: 425 MMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFWMSLYQSQ 483
MM W +FARTG+PN LP WP++N+ E+YL+++ R G K +E M FW S+
Sbjct: 496 MMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKFREAWMQFWSETLPSK 554
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 315 bits (808), Expect = 5e-86
Identities = 178/415 (42%), Positives = 245/415 (59%), Gaps = 51/415 (12%)
Query: 27 PQVVTKYGTLQGKQMHV--GKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTY 84
PQ T+ G +QGKQ+ V P+ VFLGVPF+ PPLG LRF P+P PW +R+AT+Y
Sbjct: 31 PQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSY 90
Query: 85 PPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAF 144
P CLQ S L ++ + Y SEDCLYLN+YAPA A +LPV+VWFPGGAF
Sbjct: 91 PNLCLQNSEWLLLDQHM-LKVHYPKFGVSEDCLYLNIYAPAHADTGSKLPVLVWFPGGAF 149
Query: 145 IVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQEN 204
G+AS ++GS LAA E V++V +Q+RLGIFGF +T D HA GNW DQ+AAL WVQ+N
Sbjct: 150 KTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKN 209
Query: 205 IAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRL-----FITSN 259
I FGGDP +VT+FG+SAGA+S+S L++SP+A GLFH+AI +SG A+ + S
Sbjct: 210 IEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSE 269
Query: 260 PLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMS 319
L+V VAH G N + ++ L+ CLR +++ +S K + S +
Sbjct: 270 DLQV---VAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTK---------------SFT 311
Query: 320 PVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP-------------------- 359
VVDG P++PL LL+Q ++P ++GVNN E +LLP
Sbjct: 312 RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILSGSNKSLALHLI 371
Query: 360 ---YNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHR 411
+I + + LV EY ++H +R+ ++D++ D FV L TA YHR
Sbjct: 372 QNILHIPPQYLHLVANEYFH--DKHSLTEIRDSLLDLLGDVFFVVPALITARYHR 424
Score = 82.0 bits (201), Expect = 1e-15
Identities = 36/62 (58%), Positives = 44/62 (70%)
Query: 417 KEKALSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVGMKLKEKKMAFW 476
+EK LS +MMKYWA FARTGNPN +L WP YN E+YLQLD +G +LKE ++ FW
Sbjct: 480 EEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFW 539
Query: 477 MS 478
S
Sbjct: 540 TS 541
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 254 bits (648), Expect = 2e-67
Identities = 182/593 (30%), Positives = 268/593 (45%), Gaps = 153/593 (25%)
Query: 19 LGALHTKR-PQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRPPLGILRFAPPEPPEP 74
LG+L +R P V T YG ++G + + P+ FLGVP++ PPLG RF PPE P
Sbjct: 33 LGSLGEERFPVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPAS 92
Query: 75 WKGIRDATTYPPGCLQESWGQL---------------ASMYVSTRERYKWLRFSEDCLYL 119
W G+R+ATT PP C Q G L A+ YV + SEDCLYL
Sbjct: 93 WPGVRNATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQ--------SEDCLYL 144
Query: 120 NVYAPA---------------------RAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLA 158
N+Y P R PG + PVM++ GG+++ G + ++GS LA
Sbjct: 145 NLYVPTEDGPLTKKRDEATLNPPDTDIRDPG--KKPVMLFLHGGSYMEGTGNMFDGSVLA 202
Query: 159 AREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLF 218
A V++ L +RLG+ GFLST D A+GN+GLLDQ+ ALRW+ ENIA FGGDP +T+F
Sbjct: 203 AYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIF 262
Query: 219 GQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNST 278
G AGA ++ L++S + GLF +AI+QSGTA+ + PLK + +A GC+ +
Sbjct: 263 GSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDS 322
Query: 279 QILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQG 338
V CLR +++ + P + PVVDG V+PDDP +L+ QG
Sbjct: 323 AEAVECLRRKPSRELV-----------DQDVQPARYHIAFGPVVDGDVVPDDPEILMQQG 371
Query: 339 KVSSVPYLLGVNN------LEFNWLLPYNITKEQVPLVVEEYLDNVNEH----------- 381
+ + L+GVN +E + ++ V ++DN+ +
Sbjct: 372 EFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETI 431
Query: 382 -----DW------KMLRNRMMDIVQDATFVYATLQTAH--------------YHRGLSMG 416
DW +M R ++ + D +V + TA YH + G
Sbjct: 432 KFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEG 491
Query: 417 KEK----------------------------------ALSLQMMKYWANFARTGNPNDG- 441
+ + LS +M YW NFA+TG+PN
Sbjct: 492 RPEWADAAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPV 551
Query: 442 --------------NLPCWPRYN-KDEKYLQLDFTTRVGMKLKEKKMAFWMSL 479
W ++N K+++YL + RV + K+AFW+ L
Sbjct: 552 PQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLEL 604
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 251 bits (640), Expect = 1e-66
Identities = 186/538 (34%), Positives = 255/538 (47%), Gaps = 105/538 (19%)
Query: 29 VVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGC 88
V + G L+G ++ P+ FLG+PF+ PP+G RF PPEP +PW G+ DATT+ C
Sbjct: 41 VTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVC 100
Query: 89 LQESWGQLASMYVSTRERYKW---LRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFI 145
Q + ++Y W SEDCLYLNV+ P P P PV+VW GG F
Sbjct: 101 YQ----YVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPT-PVLVWIYGGGFY 155
Query: 146 VGAASS--YEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSH-ARGNWGLLDQMAALRWVQ 202
GA+S Y+G L E+ VLV + +R+G FGFL+ S A GN GLLDQ AL+WVQ
Sbjct: 156 SGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQ 215
Query: 203 ENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSG--TALFRLFITSNP 260
EN+AAFGGDP +VTLFG+SAGA S+ ++SP + GLFHRA+ QSG +
Sbjct: 216 ENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEA 275
Query: 261 LKVAKKVAHLAGC-----NHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEII 315
+ A ++AHL GC N T+ LV CLR + V+++ L P+E +
Sbjct: 276 RRRATQLAHLVGCPPGGTGGNDTE-LVACLRTRPAQ--VLVNHEWHVL-------PQESV 325
Query: 316 WSMS--PVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPY---NITKEQVPL- 369
+ S PVVDG + D P L+ G + L+GV E ++ L Y +K+ L
Sbjct: 326 FRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLI 385
Query: 370 -----------------------VVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQT 406
VV Y D ++ D LR + D+V D V Q
Sbjct: 386 SRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQL 445
Query: 407 A--------------HYHRGLSM-----------------------------GKEKALSL 423
A HR ++ +EK +
Sbjct: 446 AGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQ 505
Query: 424 QMMKYWANFARTGNPN---DGNLPCWPRYNKD-EKYLQLDF-TTRVGMKLKEKKMAFW 476
++M+YWANFARTG+PN D P WP Y ++Y+ LD V L+ + AFW
Sbjct: 506 RLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFW 563
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 251 bits (640), Expect = 1e-66
Identities = 186/538 (34%), Positives = 255/538 (47%), Gaps = 105/538 (19%)
Query: 29 VVTKYGTLQGKQMHVGKTPIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGC 88
V + G L+G ++ P+ FLG+PF+ PP+G RF PPEP +PW G+ DATT+ C
Sbjct: 41 VTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVC 100
Query: 89 LQESWGQLASMYVSTRERYKW---LRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFI 145
Q + ++Y W SEDCLYLNV+ P P P PV+VW GG F
Sbjct: 101 YQ----YVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPT-PVLVWIYGGGFY 155
Query: 146 VGAASS--YEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSH-ARGNWGLLDQMAALRWVQ 202
GA+S Y+G L E+ VLV + +R+G FGFL+ S A GN GLLDQ AL+WVQ
Sbjct: 156 SGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQ 215
Query: 203 ENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSG--TALFRLFITSNP 260
EN+AAFGGDP +VTLFG+SAGA S+ ++SP + GLFHRA+ QSG +
Sbjct: 216 ENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEA 275
Query: 261 LKVAKKVAHLAGC-----NHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEII 315
+ A ++AHL GC N T+ LV CLR + V+++ L P+E +
Sbjct: 276 RRRATQLAHLVGCPPGGTGGNDTE-LVACLRTRPAQ--VLVNHEWHVL-------PQESV 325
Query: 316 WSMS--PVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPY---NITKEQVPL- 369
+ S PVVDG + D P L+ G + L+GV E ++ L Y +K+ L
Sbjct: 326 FRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLI 385
Query: 370 -----------------------VVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQT 406
VV Y D ++ D LR + D+V D V Q
Sbjct: 386 SRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQL 445
Query: 407 A--------------HYHRGLSM-----------------------------GKEKALSL 423
A HR ++ +EK +
Sbjct: 446 AGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQ 505
Query: 424 QMMKYWANFARTGNPN---DGNLPCWPRYNKD-EKYLQLDF-TTRVGMKLKEKKMAFW 476
++M+YWANFARTG+PN D P WP Y ++Y+ LD V L+ + AFW
Sbjct: 506 RLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFW 563
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 234 bits (598), Expect = 1e-61
Identities = 145/384 (37%), Positives = 200/384 (52%), Gaps = 58/384 (15%)
Query: 7 WSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRPPLGI 63
W L+L L A T A P V T +G L+G ++ + P+ +LGVP++ PP+G
Sbjct: 27 WFLSLALRASTQAPA-----PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGE 81
Query: 64 LRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFS---------- 113
RF PPEPP W GIR+AT +PP C Q + + + W +
Sbjct: 82 KRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPV-----WFTANLDIVATYIQE 136
Query: 114 --EDCLYLNVYAP--------------ARAPGDPQ--------LPVMVWFPGGAFIVGAA 149
EDCLYLNVY P A GD PVMV+ GG+++ G
Sbjct: 137 PNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTG 196
Query: 150 SSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFG 209
+ +GS LA+ V+++ L +R+G+ GFLST D A+GN+GLLDQ+ ALRWV ENIA FG
Sbjct: 197 NMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFG 256
Query: 210 GDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAH 269
GDP +T+FG GA +S L +S + GLF RAI QSG+AL + P+K +A
Sbjct: 257 GDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLAD 316
Query: 270 LAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPD 329
GCN T +V+CLR S +++ + P + PV+DG VIPD
Sbjct: 317 KVGCNVLDTVDMVDCLRQKSAKELVEQDIQ-----------PARYHVAFGPVIDGDVIPD 365
Query: 330 DPLVLLTQGKVSSVPYLLGVNNLE 353
DP +L+ QG+ + +LGVN E
Sbjct: 366 DPEILMEQGEFLNYDIMLGVNQGE 389
Score = 42.7 bits (99), Expect = 7e-04
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 16/75 (21%)
Query: 421 LSLQMMKYWANFARTGNPNDG---------------NLPCWPRYN-KDEKYLQLDFTTRV 464
LS +M YW NFA+TG+PN W +YN +D+ YL + RV
Sbjct: 533 LSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRV 592
Query: 465 GMKLKEKKMAFWMSL 479
+ K+AFW L
Sbjct: 593 RDHYRATKVAFWKHL 607
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 231 bits (588), Expect = 1e-60
Identities = 139/370 (37%), Positives = 196/370 (52%), Gaps = 39/370 (10%)
Query: 4 ILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRPP 60
+L W L + + L + P V T YG ++G + + P++ +LGVP++ PP
Sbjct: 25 VLLWLTALAI--KFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPP 82
Query: 61 LGILRFAPPEPPEPWKGIRDATTYPPGCLQES------------W--GQLASMYVSTRER 106
G RF PPEPP W GIR+ T + C Q W L ++ +++
Sbjct: 83 TGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQ 142
Query: 107 YKWLRFSEDCLYLNVYAPARAPGDPQ---LPVMVWFPGGAFIVGAASSYEGSDLAAREKV 163
+EDCLYLN+Y P Q PVMV+ GG+++ G + +GS LA+ V
Sbjct: 143 ------NEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNV 196
Query: 164 VLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAG 223
+++ + +RLGI GFLST D A+GN+GLLDQ+ ALRW++EN+ AFGGDP VT+FG AG
Sbjct: 197 IVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAG 256
Query: 224 AMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVN 283
A +S L +S + GLF +AI QSGTAL + P K + +A GCN T +V
Sbjct: 257 ASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVE 316
Query: 284 CLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSV 343
CLR N +Q P + PV+DG VIPDDP +L+ QG+ +
Sbjct: 317 CLRN---------KNYKELIQQTI--TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNY 365
Query: 344 PYLLGVNNLE 353
+LGVN E
Sbjct: 366 DIMLGVNQGE 375
Score = 45.8 bits (107), Expect = 9e-05
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 16/75 (21%)
Query: 421 LSLQMMKYWANFARTGNPNDG---------------NLPCWPRYN-KDEKYLQLDFTTRV 464
LS +M YW NFA+TG+PN W +YN KD+ YL + RV
Sbjct: 519 LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRV 578
Query: 465 GMKLKEKKMAFWMSL 479
+ K+AFW+ L
Sbjct: 579 RDHYRATKVAFWLEL 593
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 231 bits (588), Expect = 1e-60
Identities = 139/370 (37%), Positives = 196/370 (52%), Gaps = 39/370 (10%)
Query: 4 ILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRPP 60
+L W L + + L + P V T YG ++G + + P++ +LGVP++ PP
Sbjct: 25 VLLWLTALAI--KFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPP 82
Query: 61 LGILRFAPPEPPEPWKGIRDATTYPPGCLQES------------W--GQLASMYVSTRER 106
G RF PPEPP W GIR+ T + C Q W L ++ +++
Sbjct: 83 TGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQ 142
Query: 107 YKWLRFSEDCLYLNVYAPARAPGDPQ---LPVMVWFPGGAFIVGAASSYEGSDLAAREKV 163
+EDCLYLN+Y P Q PVMV+ GG+++ G + +GS LA+ V
Sbjct: 143 ------NEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNV 196
Query: 164 VLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAG 223
+++ + +RLGI GFLST D A+GN+GLLDQ+ ALRW++EN+ AFGGDP VT+FG AG
Sbjct: 197 IVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAG 256
Query: 224 AMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVN 283
A +S L +S + GLF +AI QSGTAL + P K + +A GCN T +V
Sbjct: 257 ASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVE 316
Query: 284 CLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSV 343
CLR N +Q P + PV+DG VIPDDP +L+ QG+ +
Sbjct: 317 CLRN---------KNYKELIQQTI--TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNY 365
Query: 344 PYLLGVNNLE 353
+LGVN E
Sbjct: 366 DIMLGVNQGE 375
Score = 45.8 bits (107), Expect = 9e-05
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 16/75 (21%)
Query: 421 LSLQMMKYWANFARTGNPNDG---------------NLPCWPRYN-KDEKYLQLDFTTRV 464
LS +M YW NFA+TG+PN W +YN KD+ YL + RV
Sbjct: 519 LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRV 578
Query: 465 GMKLKEKKMAFWMSL 479
+ K+AFW+ L
Sbjct: 579 RDHYRATKVAFWLEL 593
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 229 bits (584), Expect = 4e-60
Identities = 148/385 (38%), Positives = 202/385 (52%), Gaps = 62/385 (16%)
Query: 9 LTLCLMAQTALGALHTKR-------PQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSR 58
LTLC++ L A H P V T +G ++G + + P+ FLGVP++
Sbjct: 29 LTLCMLG-CLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAA 87
Query: 59 PPLGILRFAPPEPPEPWKGIRDATTYPPGCLQES------------WG----QLASMYVS 102
PP G RF PPEPP PW IR+AT + P C Q W + S YV
Sbjct: 88 PPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQ 147
Query: 103 TRERYKWLRFSEDCLYLNVYAPA----RAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLA 158
+ SEDCLYLN+Y P R G P+ PVMV+ GG+++ G + Y+GS LA
Sbjct: 148 DQ--------SEDCLYLNIYVPTEDDIRDSGGPK-PVMVYIHGGSYMEGTGNLYDGSVLA 198
Query: 159 AREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLF 218
+ V+++ + +RLG+ GFLST D A+GN+GLLD + ALRW ENI FGGDP +T+F
Sbjct: 199 SYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVF 258
Query: 219 GQSAGAMSISGLMMSPLA---------SGLFHRAISQSGTALFRLFITSNPLKVAKKVAH 269
G AG ++ L +S + GLF RAI+QSGTAL ++ P K A+ +A
Sbjct: 259 GSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLAT 318
Query: 270 LAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQR-DPEEIIWSMSPVVDGVVIP 328
GCN + T LV CL+ K + +L Q P + PV+DG VIP
Sbjct: 319 KVGCNVSDTVELVECLQ------------KKPYKELVDQDIQPARYHIAFGPVIDGDVIP 366
Query: 329 DDPLVLLTQGKVSSVPYLLGVNNLE 353
DDP +L+ QG+ + +LGVN E
Sbjct: 367 DDPQILMEQGEFLNYDIMLGVNQGE 391
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 227 bits (579), Expect = 2e-59
Identities = 140/368 (38%), Positives = 192/368 (52%), Gaps = 35/368 (9%)
Query: 4 ILCWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRPP 60
+L W L + + L + P V T YG +QG + + P++ +LGVP++ PP
Sbjct: 25 VLLWITALAI--KFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPP 82
Query: 61 LGILRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFS------- 113
G RF PPE P W GIR+AT + C Q L ++ W S
Sbjct: 83 TGERRFQPPESPSSWTGIRNATQFSAVCPQH----LDERFLLHDMLPIWFTTSLDTLMTY 138
Query: 114 -----EDCLYLNVYAPARAPGDPQ---LPVMVWFPGGAFIVGAASSYEGSDLAAREKVVL 165
EDCLYLN+Y P Q PVMV+ GG+++ G + +GS LA+ V++
Sbjct: 139 VQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIV 198
Query: 166 VFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAM 225
+ + RLGI GFLST D A+GN+GLLDQ+ ALRW++EN+ AFGGDP VT+FG AGA
Sbjct: 199 ITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGAS 258
Query: 226 SISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCL 285
+S L +S + GLF +AI QSGTAL + P K + +A GCN T +V CL
Sbjct: 259 CVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECL 318
Query: 286 RALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPY 345
+ N +Q P + PV+DG VIPDDP +L+ QG+ +
Sbjct: 319 KN---------KNYKELIQQTI--TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDI 367
Query: 346 LLGVNNLE 353
+LGVN E
Sbjct: 368 MLGVNQGE 375
Score = 45.8 bits (107), Expect = 9e-05
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 16/75 (21%)
Query: 421 LSLQMMKYWANFARTGNPNDG---------------NLPCWPRYN-KDEKYLQLDFTTRV 464
LS +M YW NFA+TG+PN W +YN KD+ YL + RV
Sbjct: 519 LSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRV 578
Query: 465 GMKLKEKKMAFWMSL 479
+ K+AFW+ L
Sbjct: 579 RDHYRATKVAFWLEL 593
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 222 bits (566), Expect = 5e-58
Identities = 178/570 (31%), Positives = 264/570 (46%), Gaps = 122/570 (21%)
Query: 5 LCWSLTLCLMAQTALGALHTKRPQVV-TKYGTLQGKQMHVGKTPIQVFLGVPFSRPPLGI 63
L W L LC++ +G HT+ ++ TK G ++G + V + FLG+P+++PPLG
Sbjct: 13 LFWFLLLCML----IGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGR 68
Query: 64 LRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYA 123
LRF P+ W I +AT Y C Q + S SEDCLYLNV+
Sbjct: 69 LRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPN-TDLSEDCLYLNVWI 127
Query: 124 PARAPGDPQLPVMVWFPGGAFIVGAASS--YEGSDLAAREKVVLVFLQHRLGIFGFLSTD 181
PA P + V++W GG F G +S Y+G LA E+V++V + +R+G GFL+
Sbjct: 128 PAPKPKNAT--VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALP 185
Query: 182 DS-HARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLF 240
+ A GN GL DQ AL+WVQ+NIAAFGG+P +VTLFG+SAGA S+S ++SP + LF
Sbjct: 186 GNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLF 245
Query: 241 HRAISQSGTALFRLFITS--NPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSN 298
RAI QSG+ +TS +A L GC+ + ++ CLR
Sbjct: 246 TRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLR------------ 293
Query: 299 KMRFLQLNFQRDPEEIIW--------------SMSPVVDGVVIPDDPLVLLTQGKVSSVP 344
+DP+EI+ + P VDG + D P +LL G+
Sbjct: 294 ---------NKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQ 344
Query: 345 YLLGVNNLEFNWLLPYN-----------ITKEQVPLVVEEYLDNVNEH----------DW 383
L+GVN E L Y IT+++ ++ + V+E DW
Sbjct: 345 ILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDW 404
Query: 384 ------KMLRNRMMDIVQDATFVYATLQTA------------HY--HR------------ 411
+ R + D+V D F+ L+ +Y HR
Sbjct: 405 VDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGV 464
Query: 412 ----------GLSMGK-------EKALSLQMMKYWANFARTGNPND--GNLPCWPRY-NK 451
GL + + E+ LS ++K WANFA+ GNPN+ N WP + +
Sbjct: 465 MHGYEIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKST 524
Query: 452 DEKYLQLDF-TTRVGMKLKEKKMAFWMSLY 480
++KYL L+ +TR+ KL+ ++ FW S +
Sbjct: 525 EQKYLTLNTESTRIMTKLRAQQCRFWTSFF 554
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 199 bits (506), Expect = 5e-51
Identities = 126/359 (35%), Positives = 185/359 (51%), Gaps = 43/359 (11%)
Query: 6 CWSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKT--PIQVFLGVPFSRPPLGI 63
CW++ + LGA++T+ G ++G +G + +F G+PF+ P +
Sbjct: 17 CWAVA----SAAKLGAVYTEG-------GFVEGVNKKLGLLGDSVDIFKGIPFAAPTKAL 65
Query: 64 LRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYA 123
P+P W+G A + CLQ + Q ++ EDCLYLN++
Sbjct: 66 EN---PQPHPGWQGTLKAKNFKKRCLQATITQDSTYG------------DEDCLYLNIWV 110
Query: 124 P-ARAPGDPQLPVMVWFPGGAFIVGAASS--------YEGSDLAAREKVVLVFLQHRLGI 174
P R LPVM+W GGAF++G+ Y+G ++A R V++V +R+G
Sbjct: 111 PQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGP 170
Query: 175 FGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSP 234
GFLST D++ GN+GL DQ A+ WV+ NIAAFGGDP N+TLFG+SAG S+S +SP
Sbjct: 171 LGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSP 230
Query: 235 LASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVM 294
GL RAISQSG AL I NPL AKKVA GC + CL+ ++ + +
Sbjct: 231 YNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLK-VTDPRAL 289
Query: 295 RVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLE 353
++ K+ L + P PV+DG IP DP+ L + + Y+ G NN++
Sbjct: 290 TLAYKVPLAGLEY---PMLHYVGFVPVIDGDFIPADPINL--YANAADIDYIAGTNNMD 343
Score = 35.8 bits (81), Expect = 0.091
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 9/72 (12%)
Query: 417 KEKALSLQMMKYWANFARTGNPNDGNLPC---WPRYNKDEKYLQLDFTTRVG-----MKL 468
+++ +S M+ YW NFA+TG+PN G+ W Y E L+ T ++G L
Sbjct: 479 QDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYT-TENSGYLEITKKMGSSSMKRSL 537
Query: 469 KEKKMAFWMSLY 480
+ + +W Y
Sbjct: 538 RTNFLRYWTLTY 549
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 199 bits (505), Expect = 6e-51
Identities = 116/312 (37%), Positives = 178/312 (57%), Gaps = 45/312 (14%)
Query: 141 GGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRW 200
GGAF G+AS ++GS LAA E +++V +Q+RLGIFGF +T D HA GNW DQ+AAL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 201 VQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNP 260
VQ+NI FGGDP +VT+FG+S GA+S+S LM+SP+A GLFH+A+ +SG A+ L++ ++
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAII-LYLKAHD 138
Query: 261 LKVAKK---VAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWS 317
+ ++ VA G N + ++ + CLR S +++ +S K + +
Sbjct: 139 YEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK---------------A 183
Query: 318 MSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP------------------ 359
+ VVDG P++PL LL+Q ++P ++GVNN E + LP
Sbjct: 184 FTQVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGSNKSLALC 243
Query: 360 -----YNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRG-L 413
+I + LV EY ++H +R+ ++D++ D FV L TA YHRG +
Sbjct: 244 LTQNILHILPNYLHLVAGEYFH--DKHSLTEIRDSLLDLLGDVFFVIPKLITARYHRGQI 301
Query: 414 SMGKEKALSLQM 425
G+ L +Q+
Sbjct: 302 PQGRYLLLRIQV 313
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 197 bits (501), Expect = 2e-50
Identities = 115/312 (36%), Positives = 178/312 (57%), Gaps = 45/312 (14%)
Query: 141 GGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRW 200
GGAF G+AS ++GS LAA E +++V +Q+RLGIFGF +T D HA GNW DQ+AAL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 201 VQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNP 260
VQ+NI FGGDP +VT+FG+S GA+S+S L++SP+A GLFH+A+ +SG A+ L++ ++
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAII-LYLKAHD 138
Query: 261 LKVAKK---VAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWS 317
+ ++ VA G N + ++ + CLR S +++ +S K + +
Sbjct: 139 YEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK---------------A 183
Query: 318 MSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP------------------ 359
+ VVDG P++PL LL+Q ++P ++GVNN E + LP
Sbjct: 184 FTQVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGSNKSLALC 243
Query: 360 -----YNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHYHRG-L 413
+I + LV EY ++H +R+ ++D++ D FV L TA YHRG +
Sbjct: 244 LTQNILHILPNYLHLVAGEYFH--DKHSLTEIRDSLLDLLGDVFFVIPKLITAQYHRGQI 301
Query: 414 SMGKEKALSLQM 425
G+ L +Q+
Sbjct: 302 PQGRYLLLRIQV 313
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 138 bits (347), Expect = 1e-32
Identities = 112/329 (34%), Positives = 155/329 (47%), Gaps = 32/329 (9%)
Query: 30 VTKYGTLQGKQ--MHVGKTPIQV--FLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYP 85
++ +G L G+ + VG + QV FLGVP++ PPL RF PEP W G DA+
Sbjct: 2203 ISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPR 2261
Query: 86 PGCLQESWGQLASMYVSTRERYKWLRFSEDCLYLNVYAPARAPGDPQLPVMVWFPGGAFI 145
C Q S VS EDCLYLNV+ P P V+V+F
Sbjct: 2262 ASCWQPGTRTSTSPGVS-----------EDCLYLNVFIPQNVA--PNASVLVFFHNTMDR 2308
Query: 146 VGAAS--SYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQE 203
+ + +GS LAA +++V +R+G+FGFLS+ GNWGLLDQ+AAL WVQ
Sbjct: 2309 EESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQT 2368
Query: 204 NIAAFGGDPGNVTLFGQSAGA--MSISGLMMSPLASGLFHRAISQSGTALFRLFITSN-- 259
+I FGGDP V+L GA SI L S LF RA+ G+AL + S+
Sbjct: 2369 HIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHER 2428
Query: 260 PLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMS 319
+ A +A C +S+Q +V+CLR + K+ + F W
Sbjct: 2429 AQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFH------YW--G 2480
Query: 320 PVVDGVVIPDDPLVLLTQGKVSSVPYLLG 348
PV+DG + + P L + V L+G
Sbjct: 2481 PVIDGHFLREPPARALKRSLWVEVDLLIG 2509
Score = 35.0 bits (79), Expect = 0.16
Identities = 17/49 (34%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 391 MDIVQDATFVYATLQTAHYHRGLSMGKEKALSLQMMKYWANFARTGNPN 439
++++ D F Y S+ +EK+LSL++M+Y+++F R+GNPN
Sbjct: 2622 LELLADVQFALGLPFYPAYEGQFSL-EEKSLSLKIMQYFSHFIRSGNPN 2669
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 113 bits (283), Expect = 3e-25
Identities = 51/84 (60%), Positives = 66/84 (78%)
Query: 135 VMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQ 194
V++WFPGGAF G+AS ++GS LAA E +++V +Q+RLGIFGF +T D HA GNW DQ
Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79
Query: 195 MAALRWVQENIAAFGGDPGNVTLF 218
+AAL WVQ+NI FGGDP +VT+F
Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIF 103
>gi|224589077 hypothetical protein LOC285600 isoform 1 [Homo
sapiens]
Length = 1275
Score = 33.5 bits (75), Expect = 0.45
Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 5/100 (5%)
Query: 314 IIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYNITKEQVPLVVEE 373
++W+ P + D L ++ G S++ L V +FN L V + E
Sbjct: 223 LLWNCFPSYNR----DSNLDVIAHGYQSTMLKLYSVIKEDFNTLCEILAPSSMVKFIKET 278
Query: 374 YLDNVNEHDWKMLRNRM-MDIVQDATFVYATLQTAHYHRG 412
YLD V E K L N + ++A V T +++ HRG
Sbjct: 279 YLDTVTEEMAKFLENFCELQFRENAVRVVKTSKSSSKHRG 318
>gi|27734815 hypothetical protein LOC285600 isoform 2 [Homo sapiens]
Length = 324
Score = 33.5 bits (75), Expect = 0.45
Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 5/100 (5%)
Query: 314 IIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYNITKEQVPLVVEE 373
++W+ P + D L ++ G S++ L V +FN L V + E
Sbjct: 223 LLWNCFPSYNR----DSNLDVIAHGYQSTMLKLYSVIKEDFNTLCEILAPSSMVKFIKET 278
Query: 374 YLDNVNEHDWKMLRNRM-MDIVQDATFVYATLQTAHYHRG 412
YLD V E K L N + ++A V T +++ HRG
Sbjct: 279 YLDTVTEEMAKFLENFCELQFRENAVRVVKTSKSSSKHRG 318
>gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens]
Length = 407
Score = 32.7 bits (73), Expect = 0.77
Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 12/114 (10%)
Query: 119 LNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEG--SDLAAREKVVLVFLQHRLGIFG 176
+ ++ P A P+ + +++ GGA + G+ Y G + LA + VL+ + G
Sbjct: 99 VRLFQPKAASSRPRRGI-IFYHGGATVFGSLDCYHGLCNYLARETESVLLMI-------G 150
Query: 177 FLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGL 230
+ D H+ + D M A + + +G DP V + G+S G +++ +
Sbjct: 151 YRKLPDHHSPALFQ--DCMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 32.3 bits (72), Expect = 1.0
Identities = 18/40 (45%), Positives = 20/40 (50%), Gaps = 3/40 (7%)
Query: 47 PIQVFLGVPFSRPPLGILRFAPPEPPEPWKGIRDATTYPP 86
P +F G PF +PPLG L PP PP P G PP
Sbjct: 275 PPVLFPGQPFGQPPLGPL---PPGPPPPVPGYGPPPGPPP 311
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 31.6 bits (70), Expect = 1.7
Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 4/35 (11%)
Query: 55 PFSRPPLGILRFAPPEPPEPWKGIRDATTYPPGCL 89
P RPPLG+ FAP PP G RD +P G L
Sbjct: 1806 PGMRPPLGLREFAPGVPP----GRRDLPLHPRGFL 1836
>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
Length = 895
Score = 30.0 bits (66), Expect = 5.0
Identities = 11/22 (50%), Positives = 13/22 (59%)
Query: 53 GVPFSRPPLGILRFAPPEPPEP 74
G+P PPLG+ PP PP P
Sbjct: 89 GIPMPPPPLGLPPLQPPPPPPP 110
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,934,364
Number of Sequences: 37866
Number of extensions: 941385
Number of successful extensions: 2392
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2268
Number of HSP's gapped (non-prelim): 53
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.