Search of human proteins with 23397661

Search of human proteins with 23397661

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23397661 alpha/beta hydrolase domain containing protein 2
[Homo sapiens]
         (425 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23397659 alpha/beta hydrolase domain containing protein 2 [Ho...   879   0.0  
gi|23397661 alpha/beta hydrolase domain containing protein 2 [Ho...   879   0.0  
gi|23397663 alpha/beta hydrolase domain containing protein 3 [Ho...   134   1e-31
gi|194578891 abhydrolase domain-containing protein 1 [Homo sapiens]   100   2e-21
gi|39930569 abhydrolase domain containing 15 [Homo sapiens]            67   4e-11
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled...    31   2.4  
gi|27894330 interleukin 1, alpha proprotein [Homo sapiens]             30   3.2  
gi|21389483 leucine-rich repeats and guanylate kinase domain con...    30   3.2  
gi|187960100 ubiquitin protein ligase E3C [Homo sapiens]               30   4.2  
gi|154426306 kinesin family member 24 [Homo sapiens]                   30   5.4  
gi|4506587 replication protein A3, 14kDa [Homo sapiens]                29   7.1  

>gi|23397659 alpha/beta hydrolase domain containing protein 2 [Homo
           sapiens]
          Length = 425

 Score =  879 bits (2270), Expect = 0.0
 Identities = 425/425 (100%), Positives = 425/425 (100%)

Query: 1   MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCP 60
           MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCP
Sbjct: 1   MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCP 60

Query: 61  LLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEH 120
           LLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEH
Sbjct: 61  LLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEH 120

Query: 121 CVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYG 180
           CVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYG
Sbjct: 121 CVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYG 180

Query: 181 CTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSAL 240
           CTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSAL
Sbjct: 181 CTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSAL 240

Query: 241 RAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSL 300
           RAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSL
Sbjct: 241 RAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSL 300

Query: 301 MQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLS 360
           MQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLS
Sbjct: 301 MQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLS 360

Query: 361 EKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKLQCSDTEQV 420
           EKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKLQCSDTEQV
Sbjct: 361 EKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKLQCSDTEQV 420

Query: 421 EADLE 425
           EADLE
Sbjct: 421 EADLE 425


>gi|23397661 alpha/beta hydrolase domain containing protein 2 [Homo
           sapiens]
          Length = 425

 Score =  879 bits (2270), Expect = 0.0
 Identities = 425/425 (100%), Positives = 425/425 (100%)

Query: 1   MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCP 60
           MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCP
Sbjct: 1   MNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCP 60

Query: 61  LLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEH 120
           LLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEH
Sbjct: 61  LLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEH 120

Query: 121 CVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYG 180
           CVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYG
Sbjct: 121 CVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYG 180

Query: 181 CTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSAL 240
           CTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSAL
Sbjct: 181 CTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSAL 240

Query: 241 RAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSL 300
           RAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSL
Sbjct: 241 RAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSL 300

Query: 301 MQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLS 360
           MQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLS
Sbjct: 301 MQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLVHESLLTIPKSLS 360

Query: 361 EKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKLQCSDTEQV 420
           EKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKLQCSDTEQV
Sbjct: 361 EKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQWERNKLQCSDTEQV 420

Query: 421 EADLE 425
           EADLE
Sbjct: 421 EADLE 425


>gi|23397663 alpha/beta hydrolase domain containing protein 3 [Homo
           sapiens]
          Length = 409

 Score =  134 bits (338), Expect = 1e-31
 Identities = 93/379 (24%), Positives = 172/379 (45%), Gaps = 31/379 (8%)

Query: 35  LKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHP 94
           L S    P L       SRFL   CP++T+ Y P  +W   G  QT L      + S  P
Sbjct: 49  LSSIAKKPQLVTGGESFSRFLQDHCPVVTETYYPT-VWCWEGRGQTLL---RPFITSKPP 104

Query: 95  YGHR-KFITMSDGATSTFDLFEPLAEHCVGDDIT---MVICPGIANHSEKQYIRTFVDYA 150
             +R + I  +DG   + D F+     C  D  T   +++ PG+   S++ YI   +  +
Sbjct: 105 VQYRNELIKTADGGQISLDWFDNDNSTCYMDASTRPTILLLPGLTGTSKESYILHMIHLS 164

Query: 151 QKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPLTQLVVVGFSLGG 210
           ++ GYRC V N+ G      L +PR +    T +   +++++   YP    +  G S+GG
Sbjct: 165 EELGYRCVVFNNRGVAGE-NLLTPRTYCCANTEDLETVIHHVHSLYPSAPFLAAGVSMGG 223

Query: 211 NIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETF---MQWDQCRRFYNFLMADNMKKI 267
            ++  YLG+   ++  ++   +   G++     E+    + W      +N+ +   ++  
Sbjct: 224 MLLLNYLGKI-GSKTPLMAAATFSVGWNTFACSESLEKPLNW----LLFNYYLTTCLQSS 278

Query: 268 ILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCM 327
           +  HR             ++  D+  +  A S+ + D        GY ++ +YY + S  
Sbjct: 279 VNKHRHMF----------VKQVDMDHVMKAKSIREFDKRFTSVMFGYQTIDDYYTDASPS 328

Query: 328 RYLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFP 387
             L  + +P++ +N+ DD  V      IP   +++  NV  VL  +GGH+GF EG  ++P
Sbjct: 329 PRLKSVGIPVLCLNSVDD--VFSPSHAIPIETAKQNPNVALVLTSYGGHIGFLEG--IWP 384

Query: 388 EPLTWMDKLVVEYANAICQ 406
              T+MD++  ++  A+ +
Sbjct: 385 RQSTYMDRVFKQFVQAMVE 403


>gi|194578891 abhydrolase domain-containing protein 1 [Homo sapiens]
          Length = 405

 Score =  100 bits (250), Expect = 2e-21
 Identities = 90/358 (25%), Positives = 154/358 (43%), Gaps = 27/358 (7%)

Query: 54  FLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITMSDGATSTFDL 113
           FL   C + T+ + P L W   G +Q+     +     P        +   DG     D 
Sbjct: 51  FLEPHCSITTETFYPTL-WCFEGRLQSIFQVLLQS--QPLVLYQSDILQTPDGGQLLLDW 107

Query: 114 FEPLAEHCVGDDIT---MVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIE 170
            +        D  T   +++ PGI   S++ Y+   V+ A ++GY+  V N+ G     E
Sbjct: 108 AKQPDSSQDPDPTTQPIVLLLPGITGSSQETYVLHLVNQALRDGYQAVVFNNRGCRGE-E 166

Query: 171 LTSPRMFTYGCTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVCKYLGET-QANQEKVLC 229
           L + R F    T +   +VN+IK  YP   L+ VG S GG +V  +L +  QA       
Sbjct: 167 LRTHRAFCASNTEDLETVVNHIKHRYPQAPLLAVGISFGGILVLNHLAQARQAAGLVAAL 226

Query: 230 CVSVC-QGYSALRAQETFMQWDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLED 288
            +S C   +   R+ ET +        +N  +   + +++  +R+ +        + + D
Sbjct: 227 TLSACWDSFETTRSLETPLN----SLLFNQPLTAGLCQLVERNRKVI--------EKVVD 274

Query: 289 TDLSRLYTATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADDPLV 348
            D   +  A ++ Q D+       GY     YY+  S    +  I +P++ ++AADDP  
Sbjct: 275 IDF--VLQARTIRQFDERYTSVAFGYQDCVTYYKAASPRTKIDAIRIPVLYLSAADDPF- 331

Query: 349 HESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPEPLTWMDKLVVEYANAICQ 406
              +  +P   ++    V  ++   GGH+GF EG  L P    +M +L+ +YA AI Q
Sbjct: 332 -SPVCALPIQAAQHSPYVALLITARGGHIGFLEG--LLPWQHWYMSRLLHQYAKAIFQ 386


>gi|39930569 abhydrolase domain containing 15 [Homo sapiens]
          Length = 468

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 88/384 (22%), Positives = 153/384 (39%), Gaps = 49/384 (12%)

Query: 44  LYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMGRVRSPHPYGHRKFITM 103
           L  + S L++ LL++          P  W    H+QT  +  +    +P P   R+++ +
Sbjct: 72  LVCKPSALAQCLLRALRRSEALEAGPRSWFSGPHLQTLCHFVLPV--APGPELAREYLQL 129

Query: 104 SDGATSTFDLFEPLAEHCV---------GDDITMVICPGIANHSEKQYIRTFVDYAQKNG 154
           +D      D    +   CV         G    +++ P       +  +   +  A + G
Sbjct: 130 ADDGLVALDW---VVGPCVRGRRITSAGGLPAVLLVIPNAWGRLTRNVLGLCL-LALERG 185

Query: 155 YRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPLTQLVVVGFSLGGNIVC 214
           Y   + +  G      L SPR+  +G   +    V YI+  +P   L  V    G  ++ 
Sbjct: 186 YYPVIFHRRGH-HGCPLVSPRLQPFGDPSDLKEAVTYIRFRHPAAPLFAVSEGSGSALLL 244

Query: 215 KYLGETQANQEKV-LCCVSVCQGYSALRAQETF---MQWDQCRRFYNFLMADNMKKIILS 270
            YLGE  ++       C+S       LR +E F   + W   R F         +KI LS
Sbjct: 245 SYLGECGSSSYVTGAACIS-----PVLRCREWFEAGLPWPYERGFLLH------QKIALS 293

Query: 271 HRQALFGDHVKKPQSLEDT-DLSRLYTATSLMQIDDNVMRKFHGYN-SLKEYYEEESCMR 328
                     +   +LEDT D SRL+ + SL + ++ +      +  S   Y++    +R
Sbjct: 294 ----------RYATALEDTVDTSRLFRSRSLREFEEALFCHTKSFPISWDAYWDRNDPLR 343

Query: 329 YLHRIYVPLMLVNAADDPLVHESLLTIPKSLSEKRENVMFVLPLHGGHLGFFEGSVLFPE 388
            +    VP++ + +ADDP+      T+   L         +L  HGGH GF     L  E
Sbjct: 344 DVDEAAVPVLCICSADDPVCGPPDHTLTTELFHSNPYFFLLLSRHGGHCGF-----LRQE 398

Query: 389 PL-TWMDKLVVEYANAICQWERNK 411
           PL  W  ++++E   A+ ++ R +
Sbjct: 399 PLPAWSHEVILESFRALTEFFRTE 422


>gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil
            containing 2 [Homo sapiens]
          Length = 1990

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 6/84 (7%)

Query: 144  RTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEF-GAMVNYIKKTYPLTQLV 202
            R  VD+  KNG +CA++ H     ++E+     F   C W   G      KK++ + Q +
Sbjct: 941  RAKVDHLDKNG-QCALV-HAALRGHLEVVK---FLIQCDWTMAGQQQGVFKKSHAIQQAL 995

Query: 203  VVGFSLGGNIVCKYLGETQANQEK 226
            +   S+G   +  YL +     E+
Sbjct: 996  IAAASMGYTEIVSYLLDLPEKDEE 1019


>gi|27894330 interleukin 1, alpha proprotein [Homo sapiens]
          Length = 271

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 6/81 (7%)

Query: 296 TATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADD--PLVHESLL 353
           TA +L  +D+ V      Y S K+    ++ +  + RI    + V A D+  P++ + + 
Sbjct: 153 TAAALHNLDEAVKFDMGAYKSSKD----DAKITVILRISKTQLYVTAQDEDQPVLLKEMP 208

Query: 354 TIPKSLSEKRENVMFVLPLHG 374
            IPK+++    N++F    HG
Sbjct: 209 EIPKTITGSETNLLFFWETHG 229


>gi|21389483 leucine-rich repeats and guanylate kinase domain
           containing [Homo sapiens]
          Length = 825

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 33/125 (26%), Positives = 51/125 (40%), Gaps = 27/125 (21%)

Query: 199 TQLVVVGFSLGG------NIVCKYLG----ETQANQEKVLCCVSVCQGYSALRAQETFMQ 248
           T+ V +  +L G      +I+C Y+     +  AN+ + L CVS       L A +    
Sbjct: 125 TEQVYLNLTLSGCNLIDVSILCGYVHLQKLDLSANKIEDLSCVSCMPYLLELNASQ---- 180

Query: 249 WDQCRRFYNFLMADNMKKIILSHRQALFGDHVKKPQSLEDTDLSRLYTATSLMQIDDNVM 308
            +    F+NF    N+KK   SH Q             E  DLS  +  T L+ +D N +
Sbjct: 181 -NNLTTFFNFKPPKNLKKADFSHNQI-----------SEICDLSAYHALTKLI-LDGNEI 227

Query: 309 RKFHG 313
            +  G
Sbjct: 228 EEISG 232


>gi|187960100 ubiquitin protein ligase E3C [Homo sapiens]
          Length = 1083

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 47/166 (28%), Positives = 72/166 (43%), Gaps = 30/166 (18%)

Query: 281 KKPQSLEDTDLSRLYTATSLMQIDDNVMRKFH-GYNSLKE---------YYEEESCMRYL 330
           K P S+E +DLSR+  A  L+   +NV++  H  YNS  E         + EE     + 
Sbjct: 218 KLPSSIEYSDLSRVPIAKILL---ENVLKPLHFTYNSCPEGARQQVFTAFTEEFLAAPFT 274

Query: 331 HRIYVPLMLVNAADDPLVH------ESLLTIPKSLSEKRENV----MFVLPLHGGHLGFF 380
            +I+   ++   AD   V        +LL I    S K         FVL +   +LG  
Sbjct: 275 DQIF-HFIIPALADAQTVFPYEPFLNALLLIESRCSRKSGGAPWLFYFVLTVGENYLGAL 333

Query: 381 --EGSVLFPEPL-TWMDKLVVEYANAICQWERNKLQCSDTEQVEAD 423
             EG +++   L T++ +L V  A+A C    +    S+ E  EAD
Sbjct: 334 SEEGLLVYLRVLQTFLSQLPVSPASASC---HDSASDSEEESEEAD 376


>gi|154426306 kinesin family member 24 [Homo sapiens]
          Length = 1368

 Score = 29.6 bits (65), Expect = 5.4
 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 4/58 (6%)

Query: 191 YIKKTYPLTQLVVVGFSLGGNIVCKYLGETQANQEKVLCCVSVCQGYSALRAQETFMQ 248
           Y+K T+PL Q +  G    GN  C   G+T A +   +       G  AL A++ F Q
Sbjct: 290 YMKTTHPLIQHIFNG----GNATCFAYGQTGAGKTYTMIGTHENPGLYALAAKDIFRQ 343


>gi|4506587 replication protein A3, 14kDa [Homo sapiens]
          Length = 121

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 13/38 (34%), Positives = 19/38 (50%)

Query: 86  MGRVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVG 123
           +GR+   HP G    ++  +G   T +L EPL E   G
Sbjct: 28  VGRLEKIHPTGKMFILSDGEGKNGTIELMEPLDEEISG 65


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.138    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,562,354
Number of Sequences: 37866
Number of extensions: 726536
Number of successful extensions: 1290
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1276
Number of HSP's gapped (non-prelim): 11
length of query: 425
length of database: 18,247,518
effective HSP length: 105
effective length of query: 320
effective length of database: 14,271,588
effective search space: 4566908160
effective search space used: 4566908160
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.