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Search of human proteins with 23308697
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23308697 signal recognition particle receptor [Homo sapiens]
(638 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23308697 signal recognition particle receptor [Homo sapiens] 1249 0.0
gi|4507215 signal recognition particle 54kDa isoform 1 [Homo sap... 99 9e-21
gi|226371618 signal recognition particle 54kDa isoform 2 [Homo s... 89 2e-17
gi|89061728 PREDICTED: similar to signal recognition particle 54... 59 1e-08
gi|212276104 leucine rich repeat (in FLII) interacting protein 1... 45 3e-04
gi|212276096 leucine rich repeat (in FLII) interacting protein 1... 45 3e-04
gi|212276070 leucine rich repeat (in FLII) interacting protein 1... 45 3e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|21361348 UTP14, U3 small nucleolar ribonucleoprotein, homolog... 42 0.002
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 41 0.003
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 41 0.003
gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog... 41 0.003
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 41 0.004
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 40 0.007
gi|150170670 piccolo isoform 2 [Homo sapiens] 40 0.009
gi|150378539 piccolo isoform 1 [Homo sapiens] 40 0.009
gi|105553088 t-complex 10 [Homo sapiens] 40 0.009
gi|223468602 t-complex 10-like 2 [Homo sapiens] 39 0.011
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 39 0.011
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 39 0.011
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 39 0.015
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 39 0.015
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 39 0.015
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 39 0.019
gi|87299628 biorientation of chromosomes in cell division 1-like... 39 0.019
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 39 0.019
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 39 0.019
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 39 0.019
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ... 39 0.019
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 37 0.043
>gi|23308697 signal recognition particle receptor [Homo sapiens]
Length = 638
Score = 1249 bits (3232), Expect = 0.0
Identities = 638/638 (100%), Positives = 638/638 (100%)
Query: 1 MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDN 60
MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDN
Sbjct: 1 MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDN 60
Query: 61 QFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL 120
QFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL
Sbjct: 61 QFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRL 120
Query: 121 LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP 180
LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP
Sbjct: 121 LREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGP 180
Query: 181 LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK 240
LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK
Sbjct: 181 LATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK 240
Query: 241 GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD 300
GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD
Sbjct: 241 GKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDD 300
Query: 301 EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV 360
EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV
Sbjct: 301 EGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAV 360
Query: 361 QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV 420
QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV
Sbjct: 361 QLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV 420
Query: 421 VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK 480
VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK
Sbjct: 421 VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEK 480
Query: 481 HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT 540
HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT
Sbjct: 481 HGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLIT 540
Query: 541 VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA 600
VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA
Sbjct: 541 VNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAA 600
Query: 601 ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA 638
ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA
Sbjct: 601 ISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALMKA 638
>gi|4507215 signal recognition particle 54kDa isoform 1 [Homo
sapiens]
Length = 504
Score = 99.4 bits (246), Expect = 9e-21
Identities = 68/313 (21%), Positives = 143/313 (45%), Gaps = 31/313 (9%)
Query: 324 LKGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTS 383
L+ L + ++ E + ++L ++ L+ +V + QL E+V + ++ + M +
Sbjct: 14 LRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMASGLNKRK 73
Query: 384 TVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKSTNLAKISFWLL 443
++ A+ + LV+++ P + + + V+ F G+ G GK+T +K++++
Sbjct: 74 MIQHAVFKELVKLVDPGVKAW-------TPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQ 126
Query: 444 ENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGGRTMVQLFEKGYGKDAAGIAM 503
G+ + DTFRAGA +QL+ ++ + + + D IA
Sbjct: 127 RKGWKTCLICADTFRAGAFDQLK-------------QNATKARIPFYGSYTEMDPVIIAS 173
Query: 504 EAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQL 563
E + +N+ F++++VDT+GR + L + ++ PD +++V +A +G Q
Sbjct: 174 EGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQA 233
Query: 564 VKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDL 623
F + + +++TK D K G A+S T PI+F+GTG+ D
Sbjct: 234 KAFKDKVD----------VASVIVTKLDG-HAKGGGALSAVAATKSPIIFIGTGEHIDDF 282
Query: 624 RSLNAKAVVAALM 636
+ ++ L+
Sbjct: 283 EPFKTQPFISKLL 295
>gi|226371618 signal recognition particle 54kDa isoform 2 [Homo
sapiens]
Length = 455
Score = 88.6 bits (218), Expect = 2e-17
Identities = 53/217 (24%), Positives = 100/217 (46%), Gaps = 24/217 (11%)
Query: 420 VVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPE 479
V+ F G+ G GK+T +K++++ G+ + DTFRAGA +QL+
Sbjct: 54 VIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLK------------- 100
Query: 480 KHGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLI 539
++ + + + D IA E + +N+ F++++VDT+GR + L + ++
Sbjct: 101 QNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVA 160
Query: 540 TVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGA 599
PD +++V +A +G Q F + + +++TK D K G
Sbjct: 161 NAIQPDNIVYVMDASIGQACEAQAKAFKDKVD----------VASVIVTKLDG-HAKGGG 209
Query: 600 AISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALM 636
A+S T PI+F+GTG+ D + ++ L+
Sbjct: 210 ALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLL 246
>gi|89061728 PREDICTED: similar to signal recognition particle 54kDa
[Homo sapiens]
Length = 168
Score = 59.3 bits (142), Expect = 1e-08
Identities = 35/140 (25%), Positives = 65/140 (46%), Gaps = 11/140 (7%)
Query: 497 DAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVG 556
D IA E + +N+ F++++VDT+GR + L + ++ PD +++V +A +G
Sbjct: 9 DPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIG 68
Query: 557 NEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGT 616
Q F + + +++TK D K G A+S T PI+F+GT
Sbjct: 69 QACEAQAKAFKDKVD----------VASVIVTKLDG-HAKGGGALSAVAATKSPIIFIGT 117
Query: 617 GQTYCDLRSLNAKAVVAALM 636
G+ D + ++ L+
Sbjct: 118 GEHIDDFEPFKTQPFISKLL 137
>gi|212276104 leucine rich repeat (in FLII) interacting protein 1
isoform 5 [Homo sapiens]
Length = 752
Score = 44.7 bits (104), Expect = 3e-04
Identities = 45/184 (24%), Positives = 74/184 (40%), Gaps = 30/184 (16%)
Query: 92 DKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDS----EKAKK 147
D+ RT ++ + S L+G +N + + EE + A + +D+ +K
Sbjct: 343 DRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMV 402
Query: 148 PVRSMIET-------------RGEKPKEKAKNSKKKGA---KKEGSDGPLATSKPVPAEK 191
V +ET +PKE +S + G ++EG + L KP+ E
Sbjct: 403 EVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 462
Query: 192 SGLPVGPENG---------VELSKEEL-IRRKREEFIQKHGRGMEKSNKSTKSDAPKEKG 241
G P G E V+ E L ++ EE + G ++ S K TK+ K K
Sbjct: 463 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 522
Query: 242 KKAP 245
KK+P
Sbjct: 523 KKSP 526
Score = 30.4 bits (67), Expect = 5.2
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 15/111 (13%)
Query: 133 PTTMKKFEDSEKAKKPVRSMIETRGE---KPKEKAKNSKKKGAKKEGSDGPLATSKPVPA 189
P+T+ + K+P + +GE ++K KN KKK KK+ S P+ T K V
Sbjct: 479 PSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKN-KKKKSPVPVETLKDVKK 537
Query: 190 EKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK 240
E + +L K EE ++ R ++ ++ PK+K
Sbjct: 538 E-----------LTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQK 577
>gi|212276096 leucine rich repeat (in FLII) interacting protein 1
isoform 3 [Homo sapiens]
Length = 808
Score = 44.7 bits (104), Expect = 3e-04
Identities = 45/184 (24%), Positives = 74/184 (40%), Gaps = 30/184 (16%)
Query: 92 DKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDS----EKAKK 147
D+ RT ++ + S L+G +N + + EE + A + +D+ +K
Sbjct: 399 DRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMV 458
Query: 148 PVRSMIET-------------RGEKPKEKAKNSKKKGA---KKEGSDGPLATSKPVPAEK 191
V +ET +PKE +S + G ++EG + L KP+ E
Sbjct: 459 EVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 518
Query: 192 SGLPVGPENG---------VELSKEEL-IRRKREEFIQKHGRGMEKSNKSTKSDAPKEKG 241
G P G E V+ E L ++ EE + G ++ S K TK+ K K
Sbjct: 519 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 578
Query: 242 KKAP 245
KK+P
Sbjct: 579 KKSP 582
Score = 30.4 bits (67), Expect = 5.2
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 15/111 (13%)
Query: 133 PTTMKKFEDSEKAKKPVRSMIETRGE---KPKEKAKNSKKKGAKKEGSDGPLATSKPVPA 189
P+T+ + K+P + +GE ++K KN KKK KK+ S P+ T K V
Sbjct: 535 PSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKN-KKKKSPVPVETLKDVKK 593
Query: 190 EKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK 240
E + +L K EE ++ R ++ ++ PK+K
Sbjct: 594 E-----------LTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQK 633
>gi|212276070 leucine rich repeat (in FLII) interacting protein 1
isoform 4 [Homo sapiens]
Length = 784
Score = 44.7 bits (104), Expect = 3e-04
Identities = 45/184 (24%), Positives = 74/184 (40%), Gaps = 30/184 (16%)
Query: 92 DKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDS----EKAKK 147
D+ RT ++ + S L+G +N + + EE + A + +D+ +K
Sbjct: 375 DRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMV 434
Query: 148 PVRSMIET-------------RGEKPKEKAKNSKKKGA---KKEGSDGPLATSKPVPAEK 191
V +ET +PKE +S + G ++EG + L KP+ E
Sbjct: 435 EVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 494
Query: 192 SGLPVGPENG---------VELSKEEL-IRRKREEFIQKHGRGMEKSNKSTKSDAPKEKG 241
G P G E V+ E L ++ EE + G ++ S K TK+ K K
Sbjct: 495 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 554
Query: 242 KKAP 245
KK+P
Sbjct: 555 KKSP 558
Score = 30.4 bits (67), Expect = 5.2
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 15/111 (13%)
Query: 133 PTTMKKFEDSEKAKKPVRSMIETRGE---KPKEKAKNSKKKGAKKEGSDGPLATSKPVPA 189
P+T+ + K+P + +GE ++K KN KKK KK+ S P+ T K V
Sbjct: 511 PSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKN-KKKKSPVPVETLKDVKK 569
Query: 190 EKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEK 240
E + +L K EE ++ R ++ ++ PK+K
Sbjct: 570 E-----------LTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQK 609
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPL 181
+E E K K+ + EK +K R E +GE+ KE+ + KK+ +KE +G
Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE-RERKKRRREKENKEGEE 111
Query: 182 ATSKPVPAEKSGLPVGPENGVELSKEELIRRKREE-FIQKHGRGMEKSNKSTKSDAPKEK 240
+ +K E KEE R +R+E +K R E+ K K K+
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171
Query: 241 GKK 243
G+K
Sbjct: 172 GEK 174
Score = 35.0 bits (79), Expect = 0.21
Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 8/130 (6%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPV-----RSMIETRGEKPKEKAKNSKKKGAKKEG 176
+E E K R K+ E+ EK KK R+ E + + KE+ K ++K +++
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 177 SDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDA 236
+ + ++ VG + KE R+KRE + R E+ K + +
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER--NRKERKKERERKE-RRER 208
Query: 237 PKEKGKKAPR 246
KE+ KK R
Sbjct: 209 KKERKKKEER 218
>gi|21361348 UTP14, U3 small nucleolar ribonucleoprotein, homolog A
[Homo sapiens]
Length = 771
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/132 (29%), Positives = 61/132 (46%), Gaps = 11/132 (8%)
Query: 119 RLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSD 178
R LR+ E S+ P ++ +DS + V S + +K KE ++ K+K A EG+
Sbjct: 428 RSLRKRSELSQDAEPAGSQETKDS--GSQEVLSELRVLSQKLKENHQSRKQK-ASSEGTI 484
Query: 179 GPLATSKPVPAEKSGLPVGPENGV-------ELSKEELIRRKREEFIQKHGRGMEKSNKS 231
+ +P P E+ L + V EL KEE + K G+ E++ +
Sbjct: 485 PQVQREEPAPEEEEPLLLQRPERVQTLEELEELGKEECFQNKELPRPVLEGQQSERT-PN 543
Query: 232 TKSDAPKEKGKK 243
+ DAPKEK KK
Sbjct: 544 NRPDAPKEKKKK 555
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 41.2 bits (95), Expect = 0.003
Identities = 61/282 (21%), Positives = 116/282 (41%), Gaps = 28/282 (9%)
Query: 120 LLREAEESSKIRAPTTMKKFEDSEKAKKPV-RSMIETRGEKP------KEKAKNSKKKGA 172
L+ +A+ +A + + K EK K PV +S +E +G+ P +EK K+ K
Sbjct: 601 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 660
Query: 173 KKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNK-S 231
+E P++ S KS +P P + SK E+ + +++E +K + K K
Sbjct: 661 VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK-SKAEVGKGEQKEEEEKEVKEAPKEEKVE 719
Query: 232 TKSDAPKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQ-- 289
K + PK+ +K + A EV+ + S ++L + T G+
Sbjct: 720 KKEEKPKDVPEKKKAESPVKEEAVAEVVTITK-----------SVKVHLEKETKEEGKPL 768
Query: 290 LQDLDCSSSDDEGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHL 349
Q+ + + EG ++ KG+ + + G + + +E E + +
Sbjct: 769 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKG 828
Query: 350 IAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQE 391
+ N D++ + +K E KV+ VT TV++ E
Sbjct: 829 VVTN-GLDLSPADEKKGGDKSEEKVV-----VTKTVEKITSE 864
Score = 35.4 bits (80), Expect = 0.16
Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 5/136 (3%)
Query: 123 EAE-ESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPL 181
EAE E + A K E SE+ + + + EKP EKAK+ K +E P+
Sbjct: 572 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP-EKAKSPVPKSPVEEKGKSPV 630
Query: 182 ATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKG 241
S P E+ G P++ VE + + + E K + KS PK
Sbjct: 631 PKS---PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 687
Query: 242 KKAPRVWELGGCANKE 257
++A E+G KE
Sbjct: 688 EEAKSKAEVGKGEQKE 703
Score = 34.7 bits (78), Expect = 0.28
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 10/160 (6%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIE--TRGE-KP----KEKAKNSKKKGAKK 174
++ E K +P + + K V+ +E T+ E KP KEK K + G+++
Sbjct: 726 KDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEE 785
Query: 175 EGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKS 234
EGSD S+ +G G E + +KE+ R+ E+ + +G + +++
Sbjct: 786 EGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGG 845
Query: 235 DAPKEK---GKKAPRVWELGGCANKEVLDYSTPTTNGTPE 271
D +EK K ++ GG + + S T E
Sbjct: 846 DKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEE 885
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 41.2 bits (95), Expect = 0.003
Identities = 61/282 (21%), Positives = 116/282 (41%), Gaps = 28/282 (9%)
Query: 120 LLREAEESSKIRAPTTMKKFEDSEKAKKPV-RSMIETRGEKP------KEKAKNSKKKGA 172
L+ +A+ +A + + K EK K PV +S +E +G+ P +EK K+ K
Sbjct: 225 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 284
Query: 173 KKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNK-S 231
+E P++ S KS +P P + SK E+ + +++E +K + K K
Sbjct: 285 VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK-SKAEVGKGEQKEEEEKEVKEAPKEEKVE 343
Query: 232 TKSDAPKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQ-- 289
K + PK+ +K + A EV+ + S ++L + T G+
Sbjct: 344 KKEEKPKDVPEKKKAESPVKEEAVAEVVTITK-----------SVKVHLEKETKEEGKPL 392
Query: 290 LQDLDCSSSDDEGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHL 349
Q+ + + EG ++ KG+ + + G + + +E E + +
Sbjct: 393 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKG 452
Query: 350 IAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQE 391
+ N D++ + +K E KV+ VT TV++ E
Sbjct: 453 VVTN-GLDLSPADEKKGGDKSEEKVV-----VTKTVEKITSE 488
Score = 35.4 bits (80), Expect = 0.16
Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 5/136 (3%)
Query: 123 EAE-ESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPL 181
EAE E + A K E SE+ + + + EKP EKAK+ K +E P+
Sbjct: 196 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP-EKAKSPVPKSPVEEKGKSPV 254
Query: 182 ATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKG 241
S P E+ G P++ VE + + + E K + KS PK
Sbjct: 255 PKS---PVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 311
Query: 242 KKAPRVWELGGCANKE 257
++A E+G KE
Sbjct: 312 EEAKSKAEVGKGEQKE 327
Score = 34.7 bits (78), Expect = 0.28
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 10/160 (6%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIE--TRGE-KP----KEKAKNSKKKGAKK 174
++ E K +P + + K V+ +E T+ E KP KEK K + G+++
Sbjct: 350 KDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEE 409
Query: 175 EGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKS 234
EGSD S+ +G G E + +KE+ R+ E+ + +G + +++
Sbjct: 410 EGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGG 469
Query: 235 DAPKEK---GKKAPRVWELGGCANKEVLDYSTPTTNGTPE 271
D +EK K ++ GG + + S T E
Sbjct: 470 DKSEEKVVVTKTVEKITSEGGDGATKYITKSVTVTQKVEE 509
>gi|51871374 UTP14, U3 small nucleolar ribonucleoprotein, homolog C
[Homo sapiens]
Length = 766
Score = 41.2 bits (95), Expect = 0.003
Identities = 38/138 (27%), Positives = 62/138 (44%), Gaps = 16/138 (11%)
Query: 120 LLREAEESSKIRAPTTMKKF-------EDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGA 172
LLRE EE +R + + + E + + + V S + +K KEK ++ K+K A
Sbjct: 418 LLREFEERQSLRKRSELNQDAEPASSQETKDSSSQEVLSELRALSQKLKEKHQSRKQK-A 476
Query: 173 KKEGSDGPLATSKPVPAEKSGLPVGPENGV-------ELSKEELIRRKREEFIQKHGRGM 225
EG+ + +P P E L + V EL KE+ + K G+
Sbjct: 477 SSEGTVPQVQREEPAPEEAEPLLLQRSERVQTLEELEELGKEDCFQNKELPRPVLEGQQS 536
Query: 226 EKSNKSTKSDAPKEKGKK 243
E++ + + DAPKEK +K
Sbjct: 537 ERT-PNNRPDAPKEKKEK 553
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 40.8 bits (94), Expect = 0.004
Identities = 49/194 (25%), Positives = 83/194 (42%), Gaps = 24/194 (12%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPK---EKAKNSKKKGAKKEGSD 178
R+AEES I + D E PV +E +G + K E +++K G ++EG +
Sbjct: 396 RKAEESMGIGSEEKPGTGRD-EAEMSPV---VERKGGEKKLELESRGSAEKLGTEREGGE 451
Query: 179 GPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKS--DA 236
PL + V G E +EE+ EE + +G E+ ++TK +A
Sbjct: 452 EPLGIERKVEGHLRAEKEGDEEKRGAEEEEV-----EEPLGVEKKGGEEEPEATKEPLEA 506
Query: 237 PKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCS 296
++ G++ + GG + E T T GT D+NL +G+ G + Q + +
Sbjct: 507 ERKGGEETLEAEKRGGEESLE-----TEKTQGT-----EGDLNLEQGSREGSESQAEEMN 556
Query: 297 SSDDEGAAQNSTKP 310
+ A T+P
Sbjct: 557 EAGPPLEANTETRP 570
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 40.0 bits (92), Expect = 0.007
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 4/129 (3%)
Query: 121 LREAEESSKIRAPTTMKKFEDSEKAKKPVRSM-IETRGEKPKEKAKNSKKKGAKKEGSDG 179
+++ E+ K +KK E+ K+P + + ET ++ K++ K +KK KKE +
Sbjct: 669 IKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEP 728
Query: 180 PLATSK-PVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPK 238
K P A+KS P+ K ++ K+EE ++K K + K K
Sbjct: 729 KKEIKKLPKDAKKSSTPLSEAKKPAALKPKV--PKKEESVKKDSVAAGKPKEKGKIKVIK 786
Query: 239 EKGKKAPRV 247
++GK A V
Sbjct: 787 KEGKAAEAV 795
Score = 37.7 bits (86), Expect = 0.033
Identities = 33/156 (21%), Positives = 63/156 (40%), Gaps = 27/156 (17%)
Query: 123 EAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPLA 182
+A + ++ T +K + E+ +KP + + + + P +K + KK+ KKE
Sbjct: 631 KAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKE------- 683
Query: 183 TSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKGK 242
K + E+ P K+E+ + + ++K + EK + PK++ K
Sbjct: 684 VKKEIKKEEKKEP----------KKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIK 733
Query: 243 KAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDI 278
K P K+ STP + AAL +
Sbjct: 734 KLP----------KDAKKSSTPLSEAKKPAALKPKV 759
Score = 33.5 bits (75), Expect = 0.62
Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 125 EESSKIRAPTTMKKFEDSEKAKKPVRS--MIETRGEKPKEKAKNSKKKGAKKEGSDGPLA 182
E S K+ + KK E EKA KP + + RGE+ ++ KN+ A K
Sbjct: 2279 ESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAG 2338
Query: 183 TSKPVPAEKSGLPVG 197
+ S +P G
Sbjct: 2339 PGTTKTTKSSAVPPG 2353
Score = 29.6 bits (65), Expect = 8.9
Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 13/129 (10%)
Query: 123 EAEESSKIRAPTTMKKFEDSEKAK----KPVRSMIE---TRGEKP-KEKAKNSKKKGAKK 174
E E +K+ K E EK KP+++ + T E P KE+ K + A+K
Sbjct: 564 ETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEK 623
Query: 175 EGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKS 234
+ +D +K +K V PE+ KEE + K+E ++ ++K K K
Sbjct: 624 QATDVKPKAAKEKTVKKE-TKVKPED----KKEEKEKPKKEVAKKEDKTPIKKEEKPKKE 678
Query: 235 DAPKEKGKK 243
+ KE K+
Sbjct: 679 EVKKEVKKE 687
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 39.7 bits (91), Expect = 0.009
Identities = 54/279 (19%), Positives = 100/279 (35%), Gaps = 15/279 (5%)
Query: 118 LRLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGS 177
L ++E KI T + ++ K +K S ++ + P+EK +++ + E
Sbjct: 1173 LEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 178 DGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQK-HGRGMEKSNKSTKSDA 236
L KP P +K LP + E K +L++ + + +K GR K+ + K
Sbjct: 1233 KPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQ 1292
Query: 237 PKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCS 296
K +G + L + D +T T P+ + + + + +D
Sbjct: 1293 TKMEGLPSGTPQSL-----PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKED---- 1343
Query: 297 SSDDEGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAA 356
D ++Q P T G+ L SL D + +L ++ ++ +
Sbjct: 1344 DKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 357 DIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQ 395
L KLE V+ ST+ E Q
Sbjct: 1404 SSPSDLA-----KLESTVLSILEAQASTLADEKSEKKTQ 1437
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 39.7 bits (91), Expect = 0.009
Identities = 54/279 (19%), Positives = 100/279 (35%), Gaps = 15/279 (5%)
Query: 118 LRLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGS 177
L ++E KI T + ++ K +K S ++ + P+EK +++ + E
Sbjct: 1173 LEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 178 DGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQK-HGRGMEKSNKSTKSDA 236
L KP P +K LP + E K +L++ + + +K GR K+ + K
Sbjct: 1233 KPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQ 1292
Query: 237 PKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCS 296
K +G + L + D +T T P+ + + + + +D
Sbjct: 1293 TKMEGLPSGTPQSL-----PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKED---- 1343
Query: 297 SSDDEGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLIAKNVAA 356
D ++Q P T G+ L SL D + +L ++ ++ +
Sbjct: 1344 DKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
Query: 357 DIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQ 395
L KLE V+ ST+ E Q
Sbjct: 1404 SSPSDLA-----KLESTVLSILEAQASTLADEKSEKKTQ 1437
>gi|105553088 t-complex 10 [Homo sapiens]
Length = 326
Score = 39.7 bits (91), Expect = 0.009
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 10/127 (7%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDG-- 179
R E KI P++ ++S K PV++ T ++ A+ + + + S+G
Sbjct: 185 RGVSEDGKIMHPSSRSP-QNSGGRKSPVQASQATTLQEQTAAARGADRSSSVLGSSEGGF 243
Query: 180 -------PLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKST 232
A+S P AE+ LPV P + +E+++ + K+EE ++ K++
Sbjct: 244 LSRVQADEFASSAPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPKGKADDCR 303
Query: 233 KSDAPKE 239
+S P E
Sbjct: 304 RSGFPSE 310
>gi|223468602 t-complex 10-like 2 [Homo sapiens]
Length = 353
Score = 39.3 bits (90), Expect = 0.011
Identities = 30/127 (23%), Positives = 57/127 (44%), Gaps = 10/127 (7%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDG-- 179
RE E KI P++ + ++S K PV++ ++ A + + + S+G
Sbjct: 212 REVSEDGKIMHPSS-RSLQNSGGRKSPVQASQAATLQEQTAAAGVADRSSSVLGSSEGGF 270
Query: 180 -------PLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKST 232
A+S P AE+ LPV P + +E+++ + K+EE ++ K++
Sbjct: 271 LSRVQAEEFASSSPDSAERQNLPVNPPSSLEIAQAMDTKMKKEEVQEEKRHPNGKADDCR 330
Query: 233 KSDAPKE 239
+S P E
Sbjct: 331 RSGFPSE 337
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 39.3 bits (90), Expect = 0.011
Identities = 28/124 (22%), Positives = 57/124 (45%), Gaps = 6/124 (4%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGS---- 177
+E ++ +T K+ + S KKPVR ++ + ++ +E + S +K K+GS
Sbjct: 1677 KEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKEKQKQKEEGLQASAEKAELKKGSSEES 1736
Query: 178 --DGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSD 235
+ P +P+P K+ P+ E + K+++ ++ ++ GR K D
Sbjct: 1737 LGEDPGLAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPIRVKGKED 1796
Query: 236 APKE 239
PK+
Sbjct: 1797 VPKK 1800
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 39.3 bits (90), Expect = 0.011
Identities = 39/160 (24%), Positives = 71/160 (44%), Gaps = 15/160 (9%)
Query: 92 DKYRTEIQQQSALSLLNGTFDFQNDFLRLLREA--EESSKIRAPTTMKKFEDSEKAKKPV 149
++ R E ++Q L + + LRL EA +E + R KK E EK K
Sbjct: 419 EQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKA-- 476
Query: 150 RSMIETRGEKPKEKAKNSK--KKGAKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKE 207
GE+ K KA+ K+ ++E + + + AE V + + L +E
Sbjct: 477 -------GEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQ--MRLERE 527
Query: 208 ELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRV 247
+++ + +E +++ R E ++ KSD P + K+ P+V
Sbjct: 528 QIMLQIEQERLERKKRIDEIMKRTRKSDVPPQVKKEDPKV 567
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 38.9 bits (89), Expect = 0.015
Identities = 40/135 (29%), Positives = 61/135 (45%), Gaps = 9/135 (6%)
Query: 123 EAEESSKIRAPTTMKKFE-DSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKK-EGSDGP 180
EA+ K ++P K + S +AK P + + +K EKAK+ K+ K E + P
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSP 802
Query: 181 L-----ATSKPVP-AEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKS 234
L A K +P E+ PV E + K + +K EE E+ S K
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE 862
Query: 235 DAPKEKGKKAPRVWE 249
+APK++ K P+V E
Sbjct: 863 EAPKKEAPK-PKVEE 876
Score = 38.9 bits (89), Expect = 0.015
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEK-PK-EKAKNSKKKGAKKEGSDG 179
+E + ++++P ++ K K+P + E + PK E+ K+SKK+ A K+ +
Sbjct: 812 KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK 871
Query: 180 PLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKE 239
P K PA + E+ VE KEE +K+ +K + + K E
Sbjct: 872 PKVEEKKEPAVEKP----KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTE 927
Query: 240 KGKKAP 245
KK P
Sbjct: 928 VAKKEP 933
Score = 37.4 bits (85), Expect = 0.043
Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 12/127 (9%)
Query: 123 EAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGE-KPKEKAKNSKKKGAKKEGSDGPL 181
++ E + ++P +K EKAK P + ++ E K EKAK+ K+ AK P
Sbjct: 565 KSPEKEEAKSPAEVKS---PEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS-----PA 616
Query: 182 ATSKPVPAE-KSGLPV-GPENGVELSKEELIRRKREEFIQK-HGRGMEKSNKSTKSDAPK 238
PV E KS V PE +KEE ++ + +K + EK+ K++A
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676
Query: 239 EKGKKAP 245
+ K+P
Sbjct: 677 PEKAKSP 683
Score = 37.4 bits (85), Expect = 0.043
Identities = 40/144 (27%), Positives = 61/144 (42%), Gaps = 22/144 (15%)
Query: 123 EAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGE-KPKEKAKNSKKKGAK-------- 173
EA+ K ++P + +E AK PV+ ++ E K EKAK+ K+ AK
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAE-AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655
Query: 174 -KEGSDGPLATSKPVPA-----EKSGLPV-----GPENGVELSKEEL-IRRKREEFIQKH 221
KE + P PV A EK+ PV PE KEE K + +++
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715
Query: 222 GRGMEKSNKSTKSDAPKEKGKKAP 245
+ EK+ K +A + K+P
Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSP 739
Score = 31.6 bits (70), Expect = 2.3
Identities = 33/148 (22%), Positives = 55/148 (37%), Gaps = 28/148 (18%)
Query: 125 EESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGE-------------------------K 159
EE+ K AP + + +KP S +E + E K
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921
Query: 160 PKEKAKNSKKK--GAKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEF 217
PKEK + +KK+ AK + P + P +K + E K E ++ ++
Sbjct: 922 PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Query: 218 IQKHGRGMEKSNKSTKSDAPKEKGKKAP 245
+ K K+ K+ KS + +K K P
Sbjct: 982 LSKE-PSKPKAEKAEKSSSTDQKDSKPP 1008
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 38.9 bits (89), Expect = 0.015
Identities = 45/199 (22%), Positives = 79/199 (39%), Gaps = 38/199 (19%)
Query: 97 EIQQQSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDSEKA----------- 145
+ ++++ L +++ TF + + +E ++ K A T+ K +DS K+
Sbjct: 59 QAKEKAFLPMVSHTFHMRTEESDASQEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGD 118
Query: 146 --KKPVRSMIETRGEKPK--EKAKNSKKKGAKKEGSDG--------PLATSKPVPAEKSG 193
K P ++ + + PK EKA K+ K + P A+ KP ++
Sbjct: 119 IPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGD 178
Query: 194 LPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRVWELGGC 253
+P PE ++ KE+L + E K G D PK K P +LG
Sbjct: 179 IPKAPEETIQSKKEDLPKSSEEAIQPKEG------------DIPKSSAK--PIQPKLGNI 224
Query: 254 ANKEVLDYSTPTTNGTPEA 272
A V S P + P++
Sbjct: 225 AKTSVKP-SQPKESDIPKS 242
Score = 32.7 bits (73), Expect = 1.1
Identities = 53/253 (20%), Positives = 98/253 (38%), Gaps = 27/253 (10%)
Query: 123 EAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAK--------- 173
+ +ES ++P + ++ + K + + G PK K S+ K
Sbjct: 233 QPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAI 292
Query: 174 --KEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKS 231
KEG D P + + + ++ +P PE ++ KE I + EE IQ + KS +
Sbjct: 293 QPKEG-DLPKSLEEAIQPKEGDIPKSPEEAIQ-PKEGDIPKSLEEAIQPKEGDIPKSPEE 350
Query: 232 T----KSDAPKEKGKK-APRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGS 286
T K D PK + P+ ++ + + EA ++I++ +
Sbjct: 351 TIQPKKGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEE 410
Query: 287 GGQLQDLDCSSSDDEGAAQNSTKPSATKGTLGGMFGMLKGLVGSK---SLSREDMESVLD 343
Q ++ DD + PS L ++ G K LS+ED E+ L
Sbjct: 411 TIQPKE------DDSPKSLEEATPSKEGDILKPEEETMEFPEGDKVKVILSKEDFEASLK 464
Query: 344 KMRDHLIAKNVAA 356
+ + L+A + +A
Sbjct: 465 EAGERLVAVDFSA 477
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 38.9 bits (89), Expect = 0.015
Identities = 40/146 (27%), Positives = 64/146 (43%), Gaps = 15/146 (10%)
Query: 131 RAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPLATSKPVPAE 190
+ T K+ E+ EK +KP E E+ + +K+ K E S+ + + K A+
Sbjct: 19 KGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAK 78
Query: 191 KSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKE------KGKKA 244
K P +N + + L RK++E I+K K+ K TK++ P E K KK
Sbjct: 79 KKEEP--SQNDISPKTKSL--RKKKEPIEKKVVS-SKTKKVTKNEEPSEEEIDAPKPKKM 133
Query: 245 PRVWELGGCANKEVLDYSTPTTNGTP 270
+ E+ G E + S NG P
Sbjct: 134 KKEKEMNG----ETREKSPKLKNGFP 155
Score = 30.4 bits (67), Expect = 5.2
Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Query: 114 QNDFLRLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKG-- 171
++D + E EE+ +A KK E SE +S + E+P + + K K
Sbjct: 37 KSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLR 96
Query: 172 AKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNK 230
KKE + + +SK K+ P E ++ K + +++++E +G EKS K
Sbjct: 97 KKKEPIEKKVVSSKTKKVTKNEEP--SEEEIDAPKPKKMKKEKE----MNGETREKSPK 149
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 38.5 bits (88), Expect = 0.019
Identities = 34/133 (25%), Positives = 57/133 (42%), Gaps = 12/133 (9%)
Query: 123 EAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGS----- 177
E E + R T ++ D +K ++ RS +R + KE+AK+ +KK KKE +
Sbjct: 1148 EREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPP 1207
Query: 178 ----DGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTK 233
D +K P LP+ V+ E R K E +K E+ K +
Sbjct: 1208 AKLLDDLFRKTKAAPC-IYWLPLTDSQIVQKEAERAERAKEREKRRKEQE--EEEQKERE 1264
Query: 234 SDAPKEKGKKAPR 246
+A +E+ ++ R
Sbjct: 1265 KEAERERNRQLER 1277
Score = 30.4 bits (67), Expect = 5.2
Identities = 37/163 (22%), Positives = 68/163 (41%), Gaps = 14/163 (8%)
Query: 129 KIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSK-KKGAKKEGSDGPLATSKPV 187
++RA +K E+ E+ ++ E G+ +K++ + K K+EG + P + +
Sbjct: 260 RVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEM 319
Query: 188 ----PAEKSGLPVGPENG-------VELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDA 236
P +S E G E K L R+++E+ ++ E+ + S
Sbjct: 320 MDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQG 379
Query: 237 PKEKGK--KAPRVWELGGCANKEVLDYSTPTTNGTPEAALSED 277
KEK K PR+ E A+ L T + TP L+++
Sbjct: 380 LKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKE 422
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 38.5 bits (88), Expect = 0.019
Identities = 69/340 (20%), Positives = 123/340 (36%), Gaps = 64/340 (18%)
Query: 125 EESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKN---SKKKGAKKEGSDGPL 181
+E+S RA T + SE+A K + S T KE+ K+K G +G
Sbjct: 213 QEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLE 272
Query: 182 ATSK-------PVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKS 234
K P P E+ N + L +++ + E+ + +G +K + + K
Sbjct: 273 TAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKG 332
Query: 235 DAPKEKGKK-------------APRVWELGGCANKEVLDYSTPTTNGTPEA----ALSED 277
+ KEK +K +V + KEV P+ + +A ED
Sbjct: 333 ERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKED 392
Query: 278 INLIRGTGSG----------------------------GQLQDLDCSSSDDEGAAQNSTK 309
+LI G +++ + +S D+E QN TK
Sbjct: 393 FSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTK 452
Query: 310 PSATKGTLGGMFGML-----KGLVGSKSLSREDMESVLDKMRDHLIAKNVAADIAVQL-C 363
+ + G + K + SK S D E +++ R + + + Q+
Sbjct: 453 TQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINR 512
Query: 364 ESVANKLEGKVMGTFSTVTSTVKQA---LQESLVQILQPQ 400
E + K + K T S+ T ++ L+ES + L+P+
Sbjct: 513 EKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPK 552
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 38.5 bits (88), Expect = 0.019
Identities = 48/203 (23%), Positives = 79/203 (38%), Gaps = 14/203 (6%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPL 181
+E +E+ ++ K + K++K E + +KP EK K KG K++
Sbjct: 1063 KEHQETKPVKEEKVKKDYSKDVKSEKLTTK--EEKAKKPNEKNKPLDNKGEKRKRKTEEK 1120
Query: 182 ATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPK--- 238
K E S + + E+ K +RK E +K R EK S + A K
Sbjct: 1121 GVDKDF--ESSSMKISKLEVTEIVKPS-PKRKMEPDTEKMDRTPEKDKISLSAPAKKIKL 1177
Query: 239 --EKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDI-NLIRGT-GSGGQLQDLD 294
E GKK + KE + T++ + + + + GT GS L D
Sbjct: 1178 NRETGKKIGSTENISN--TKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYT 1235
Query: 295 CSSSDDEGAAQNSTKPSATKGTL 317
+SS + S + + TK T+
Sbjct: 1236 STSSTGGSPVRKSEEKTDTKRTV 1258
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 38.5 bits (88), Expect = 0.019
Identities = 48/203 (23%), Positives = 79/203 (38%), Gaps = 14/203 (6%)
Query: 122 REAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPL 181
+E +E+ ++ K + K++K E + +KP EK K KG K++
Sbjct: 1097 KEHQETKPVKEEKVKKDYSKDVKSEKLTTK--EEKAKKPNEKNKPLDNKGEKRKRKTEEK 1154
Query: 182 ATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPK--- 238
K E S + + E+ K +RK E +K R EK S + A K
Sbjct: 1155 GVDKDF--ESSSMKISKLEVTEIVKPS-PKRKMEPDTEKMDRTPEKDKISLSAPAKKIKL 1211
Query: 239 --EKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDI-NLIRGT-GSGGQLQDLD 294
E GKK + KE + T++ + + + + GT GS L D
Sbjct: 1212 NRETGKKIGSTENISN--TKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYT 1269
Query: 295 CSSSDDEGAAQNSTKPSATKGTL 317
+SS + S + + TK T+
Sbjct: 1270 STSSTGGSPVRKSEEKTDTKRTV 1292
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 38.5 bits (88), Expect = 0.019
Identities = 34/139 (24%), Positives = 59/139 (42%), Gaps = 11/139 (7%)
Query: 114 QNDFLRLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPK--EKAKNSKKKG 171
Q + R E SK+ T + + EKA+ P + + G+K K +K K +K+
Sbjct: 269 QKESQRKFEEETVKSKVTVDTGVIPASE-EKAETPTAAEDDNEGDKKKKDKKKKKGEKEE 327
Query: 172 AKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELI--------RRKREEFIQKHGR 223
+KE GP + E E + +EE I +RK EE +++ R
Sbjct: 328 KEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKR 387
Query: 224 GMEKSNKSTKSDAPKEKGK 242
+K + + + K++GK
Sbjct: 388 ERKKQKEKERKERLKKEGK 406
Score = 29.6 bits (65), Expect = 8.9
Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 6/114 (5%)
Query: 143 EKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPLATSKPVPAEKSGLPVGPENGV 202
E + P E E+ E+++ +++ + EGS+G K + SG + +
Sbjct: 526 EVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSK 585
Query: 203 ELSKEELI-----RRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRVWELG 251
E+S + R K E K R +EK + EK +AP + LG
Sbjct: 586 EMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEK-LRAPIICVLG 638
>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
[Homo sapiens]
Length = 621
Score = 38.5 bits (88), Expect = 0.019
Identities = 71/329 (21%), Positives = 126/329 (38%), Gaps = 68/329 (20%)
Query: 114 QNDFLRLLREAEESSKIRA--------PTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAK 165
QN R R+ EE ++IR +KKF++ EKAKK + ++ +++AK
Sbjct: 250 QNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKAEAKRKEQEAK 309
Query: 166 NSKKKGAKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHG--R 223
+++ AE + E E +++ + K+E+ IQK +
Sbjct: 310 EKQRQ------------------AELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKK 351
Query: 224 GMEKSNKSTK-----SDAPKEKGKKAPRVWELGGCANKEVLDYS------TPTTNGTPEA 272
+K S K SD E+ K V +L C E+ T T +A
Sbjct: 352 ERQKLRNSCKTWNHFSDNEAERVKMMEEVEKL--CDRLELASLQCLNETLTSCTKEVGKA 409
Query: 273 ALSEDINLIRGTGSGGQLQDLDCSSSDDEGAAQNSTKPSATKGTLGGMFGMLKGLVGSKS 332
AL + I I + +E A+ T+ + GG G GSK+
Sbjct: 410 ALEKQIEEI----------NEQIRKEKEEAEARMRQASKNTEKSTGG------GGNGSKN 453
Query: 333 LSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQAL-QE 391
S +D++ ++ A N+ E +AN + + + S V T K + +
Sbjct: 454 WSEDDLQLLIK-------AVNLFPAGTNSRWEVIANYMN---IHSSSGVKRTAKDVIGKA 503
Query: 392 SLVQILQPQRRVDMLRDIMDAQRRQRPYV 420
+Q L P ++ D+ + D +++ V
Sbjct: 504 KSLQKLDPHQKDDINKKAFDKFKKEHGVV 532
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 37.4 bits (85), Expect = 0.043
Identities = 41/139 (29%), Positives = 58/139 (41%), Gaps = 16/139 (11%)
Query: 112 DFQNDFLRLLREAEESSKIRAPTTMKKFEDSEKAK---KPVRSMIETRGEKPKEKAKNSK 168
+F FL L + AP + KA+ KP + T E P EK K+
Sbjct: 36 EFLEGFLSELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRP-GTAAEVPPEKTKDKG 94
Query: 169 KKGAKKEGSDGPLATSKPVPAEK-SGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEK 227
KKG K +G VP E G P P+ G E + ++ +E+ + + EK
Sbjct: 95 KKGKKDKG--------PKVPKESLEGSPRPPKKGKE-KPPKATKKPKEKPPKATKKPKEK 145
Query: 228 SNKSTKSDAPKEKGKKAPR 246
K+TK PKEK KA +
Sbjct: 146 PPKATKK--PKEKPPKATK 162
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,493,247
Number of Sequences: 37866
Number of extensions: 1014066
Number of successful extensions: 5211
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 199
Number of HSP's that attempted gapping in prelim test: 4611
Number of HSP's gapped (non-prelim): 641
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.