Search of human proteins with 23238238

Search of human proteins with 23238238

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A
isoform 1 [Homo sapiens]
         (248 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A ...   488   e-138
gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A ...   424   e-119
gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A ...   282   2e-76
gi|21264311 membrane-spanning 4-domains, subfamily A, member 6E ...   144   7e-35
gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 i...   134   1e-31
gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 i...   134   1e-31
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [...    78   8e-15
gi|46249347 membrane-spanning 4-domains, subfamily A, member 7 i...    77   1e-14
gi|46249359 membrane-spanning 4-domains, subfamily A, member 7 i...    77   1e-14
gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A...    72   3e-13
gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A...    72   3e-13
gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A...    72   3e-13
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i...    72   6e-13
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i...    72   6e-13
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [...    69   5e-12
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i...    68   6e-12
gi|149588599 membrane-spanning 4-domains, subfamily A, member 15...    68   8e-12
gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [...    57   2e-08
gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [...    57   2e-08
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is...    53   3e-07
gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 ...    52   5e-07
gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ...    52   6e-07
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ...    51   8e-07
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14...    48   9e-06
gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, ...    42   6e-04
gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, ...    42   6e-04
gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, ...    42   6e-04
gi|73486653 membrane-spanning 4-domains, subfamily A, member 3 i...    40   0.002
gi|167466260 membrane-spanning 4-domains, subfamily A, member 10...    39   0.004
gi|16933561 sarcospan isoform 1 [Homo sapiens]                         36   0.027

>gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 1 [Homo sapiens]
          Length = 248

 Score =  488 bits (1255), Expect = e-138
 Identities = 248/248 (100%), Positives = 248/248 (100%)

Query: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
           MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
Sbjct: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60

Query: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
           SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
Sbjct: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120

Query: 121 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA 180
           SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
Sbjct: 121 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA 180

Query: 181 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHDC 240
           SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHDC
Sbjct: 181 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSSKMTHDC 240

Query: 241 GYEELLTS 248
           GYEELLTS
Sbjct: 241 GYEELLTS 248


>gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 2 [Homo sapiens]
          Length = 225

 Score =  424 bits (1090), Expect = e-119
 Identities = 217/217 (100%), Positives = 217/217 (100%)

Query: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
           MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
Sbjct: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60

Query: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
           SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
Sbjct: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120

Query: 121 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA 180
           SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA
Sbjct: 121 SILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKA 180

Query: 181 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPG 217
           SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPG
Sbjct: 181 SLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPG 217


>gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 3 [Homo sapiens]
          Length = 178

 Score =  282 bits (721), Expect = 2e-76
 Identities = 148/148 (100%), Positives = 148/148 (100%)

Query: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
           MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
Sbjct: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60

Query: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
           SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
Sbjct: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120

Query: 121 SILSALSALVGFIILSVKQATLNPASLQ 148
           SILSALSALVGFIILSVKQATLNPASLQ
Sbjct: 121 SILSALSALVGFIILSVKQATLNPASLQ 148


>gi|21264311 membrane-spanning 4-domains, subfamily A, member 6E
           [Homo sapiens]
          Length = 147

 Score =  144 bits (363), Expect = 7e-35
 Identities = 77/111 (69%), Positives = 90/111 (81%), Gaps = 1/111 (0%)

Query: 100 SLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTR 159
           SL    + ++  + VHSSL GSILSALSALVGFI+LSV  A LNPASLQC+LD+ +IPTR
Sbjct: 36  SLKKRLQAKVKVIGVHSSLAGSILSALSALVGFILLSVNPAALNPASLQCKLDEKDIPTR 95

Query: 160 SYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQ 210
             +SY YH S YT DC+ AKASLAGTLSLML+ T+LEFCLAVLTAVL+WKQ
Sbjct: 96  LLLSYDYH-SPYTMDCHRAKASLAGTLSLMLVSTVLEFCLAVLTAVLQWKQ 145



 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 47/74 (63%), Positives = 56/74 (75%)

Query: 1  MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
          MTSQP+ NETII+LPSNVINFSQAEKPEPTNQGQDSLKK L A++KVIG    L G ++ 
Sbjct: 1  MTSQPISNETIIMLPSNVINFSQAEKPEPTNQGQDSLKKRLQAKVKVIGVHSSLAGSILS 60

Query: 61 SLGIILASASFSPN 74
          +L  ++     S N
Sbjct: 61 ALSALVGFILLSVN 74


>gi|11139299 membrane-spanning 4-domains, subfamily A, member 7
           isoform 1 [Homo sapiens]
          Length = 240

 Score =  134 bits (336), Expect = 1e-31
 Identities = 80/201 (39%), Positives = 111/201 (55%), Gaps = 3/201 (1%)

Query: 19  INFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV 78
           I   Q EKP    Q +D L+  L  E  V+GT+QILC +++ SLG IL  A +  +F   
Sbjct: 19  ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPA 78

Query: 79  TSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVK 138
            ST L S YPF+G   F I+GSLSI + K+ TK    SSL  + +S+++A  G  +L+  
Sbjct: 79  ISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADS 138

Query: 139 QATLNPASLQCELDKNNIPTRSYVSYFYHDSLY-TTDCYTAKASLAGTLSLMLICTLLEF 197
              L  AS  C  + + + +  Y  Y+Y   +Y   DC     SL G L +MLI T+LE 
Sbjct: 139 MVALRTASQHCGSEMDYLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLEL 196

Query: 198 CLAVLTAVLRWKQAYSDFPGS 218
            LA  ++V  WKQ YS+ PGS
Sbjct: 197 LLAAYSSVFWWKQLYSNNPGS 217


>gi|46249357 membrane-spanning 4-domains, subfamily A, member 7
           isoform 1 [Homo sapiens]
          Length = 240

 Score =  134 bits (336), Expect = 1e-31
 Identities = 80/201 (39%), Positives = 111/201 (55%), Gaps = 3/201 (1%)

Query: 19  INFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV 78
           I   Q EKP    Q +D L+  L  E  V+GT+QILC +++ SLG IL  A +  +F   
Sbjct: 19  ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPA 78

Query: 79  TSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVK 138
            ST L S YPF+G   F I+GSLSI + K+ TK    SSL  + +S+++A  G  +L+  
Sbjct: 79  ISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADS 138

Query: 139 QATLNPASLQCELDKNNIPTRSYVSYFYHDSLY-TTDCYTAKASLAGTLSLMLICTLLEF 197
              L  AS  C  + + + +  Y  Y+Y   +Y   DC     SL G L +MLI T+LE 
Sbjct: 139 MVALRTASQHCGSEMDYLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLEL 196

Query: 198 CLAVLTAVLRWKQAYSDFPGS 218
            LA  ++V  WKQ YS+ PGS
Sbjct: 197 LLAAYSSVFWWKQLYSNNPGS 217


>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
           [Homo sapiens]
          Length = 267

 Score = 77.8 bits (190), Expect = 8e-15
 Identities = 64/189 (33%), Positives = 89/189 (47%), Gaps = 33/189 (17%)

Query: 44  EIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV---TSTLLNSAYPFIGPFFFIISGS 100
           E K +G IQI+ G+M +  GI+L   SFS  F +V    ST +   YPF G   FIISGS
Sbjct: 87  EAKALGVIQIMVGLMHIGFGIVLCLISFS--FREVLGFASTAVIGGYPFWGGLSFIISGS 144

Query: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRS 160
           LS++  K L++ LV  SL  +I+S++ A +G I+L V       A               
Sbjct: 145 LSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCINGVAGQD------------ 192

Query: 161 YVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVL 220
                          Y A  S  G  + ++I +LLEF +A  TA     QA +    SVL
Sbjct: 193 ---------------YWAVLSGKGISATLMIFSLLEFFVACATAHFA-NQANTTTNMSVL 236

Query: 221 FLPHSYIGN 229
            +P+ Y  N
Sbjct: 237 VIPNMYESN 245


>gi|46249347 membrane-spanning 4-domains, subfamily A, member 7
           isoform 2 [Homo sapiens]
          Length = 195

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 3/125 (2%)

Query: 95  FIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKN 154
           F I+GSLSI + K+ TK    SSL  + +S+++A  G  +L+     L  AS  C  + +
Sbjct: 50  FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMD 109

Query: 155 NIPTRSYVSYFYHDSLYTT-DCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYS 213
            + +  Y  Y+Y   +Y   DC     SL G L +MLI T+LE  LA  ++V  WKQ YS
Sbjct: 110 YLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWKQLYS 167

Query: 214 DFPGS 218
           + PGS
Sbjct: 168 NNPGS 172


>gi|46249359 membrane-spanning 4-domains, subfamily A, member 7
           isoform 2 [Homo sapiens]
          Length = 195

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 3/125 (2%)

Query: 95  FIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKN 154
           F I+GSLSI + K+ TK    SSL  + +S+++A  G  +L+     L  AS  C  + +
Sbjct: 50  FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMD 109

Query: 155 NIPTRSYVSYFYHDSLYTT-DCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYS 213
            + +  Y  Y+Y   +Y   DC     SL G L +MLI T+LE  LA  ++V  WKQ YS
Sbjct: 110 YLSSLPYSEYYY--PIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSVFWWKQLYS 167

Query: 214 DFPGS 218
           + PGS
Sbjct: 168 NNPGS 172


>gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 1 [Homo sapiens]
          Length = 243

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 58/173 (33%), Positives = 87/173 (50%), Gaps = 37/173 (21%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFS-----PNFTQVTSTLLNSAYPFIGP 92
           +K    + KV+G ++IL  +M LS+GII+   +FS     P F  V       AY   G 
Sbjct: 60  EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV-------AYTIWGS 112

Query: 93  FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD 152
             FIIS SLS+A   R TK LV  SL  +I S++ A+ G +I                  
Sbjct: 113 VMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILI------------------ 154

Query: 153 KNNIPTRSYVSYFY----HDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
             N  + ++ S+ Y    HD L +++CY   + L GT  ++L+ ++LEFC+AV
Sbjct: 155 --NAISLTFYSFRYHYCNHDQL-SSNCYMTMSILMGTDGMVLLLSVLEFCIAV 204


>gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 3 [Homo sapiens]
          Length = 243

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 58/173 (33%), Positives = 87/173 (50%), Gaps = 37/173 (21%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFS-----PNFTQVTSTLLNSAYPFIGP 92
           +K    + KV+G ++IL  +M LS+GII+   +FS     P F  V       AY   G 
Sbjct: 60  EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV-------AYTIWGS 112

Query: 93  FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD 152
             FIIS SLS+A   R TK LV  SL  +I S++ A+ G +I                  
Sbjct: 113 VMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILI------------------ 154

Query: 153 KNNIPTRSYVSYFY----HDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
             N  + ++ S+ Y    HD L +++CY   + L GT  ++L+ ++LEFC+AV
Sbjct: 155 --NAISLTFYSFRYHYCNHDQL-SSNCYMTMSILMGTDGMVLLLSVLEFCIAV 204


>gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 3 [Homo sapiens]
          Length = 243

 Score = 72.4 bits (176), Expect = 3e-13
 Identities = 58/173 (33%), Positives = 87/173 (50%), Gaps = 37/173 (21%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFS-----PNFTQVTSTLLNSAYPFIGP 92
           +K    + KV+G ++IL  +M LS+GII+   +FS     P F  V       AY   G 
Sbjct: 60  EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV-------AYTIWGS 112

Query: 93  FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELD 152
             FIIS SLS+A   R TK LV  SL  +I S++ A+ G +I                  
Sbjct: 113 VMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILI------------------ 154

Query: 153 KNNIPTRSYVSYFY----HDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
             N  + ++ S+ Y    HD L +++CY   + L GT  ++L+ ++LEFC+AV
Sbjct: 155 --NAISLTFYSFRYHYCNHDQL-SSNCYMTMSILMGTDGMVLLLSVLEFCIAV 204


>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
           isoform a [Homo sapiens]
          Length = 220

 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 61/194 (31%), Positives = 92/194 (47%), Gaps = 20/194 (10%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFII 97
           +K L  E KV+G +QIL  +M LS+GI +   + +   +   S  +   Y   G   FII
Sbjct: 37  EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIG--YTIWGSVMFII 94

Query: 98  SGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIP 157
           SGSLSIA   R TK LV  SL  +I S++ A  G +I +   A  +     C        
Sbjct: 95  SGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCN------- 147

Query: 158 TRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPG 217
                  +Y +S    +C+   + L G   ++L+ ++LEFC+AV  +    K       G
Sbjct: 148 -------YYGNS---NNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGG 197

Query: 218 SVLFLP-HSYIGNS 230
            VL LP HS++  +
Sbjct: 198 VVLILPSHSHMAET 211


>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
           isoform b [Homo sapiens]
          Length = 239

 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 61/194 (31%), Positives = 92/194 (47%), Gaps = 20/194 (10%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFII 97
           +K L  E KV+G +QIL  +M LS+GI +   + +   +   S  +   Y   G   FII
Sbjct: 56  EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIG--YTIWGSVMFII 113

Query: 98  SGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIP 157
           SGSLSIA   R TK LV  SL  +I S++ A  G +I +   A  +     C        
Sbjct: 114 SGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCN------- 166

Query: 158 TRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPG 217
                  +Y +S    +C+   + L G   ++L+ ++LEFC+AV  +    K       G
Sbjct: 167 -------YYGNS---NNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGG 216

Query: 218 SVLFLP-HSYIGNS 230
            VL LP HS++  +
Sbjct: 217 VVLILPSHSHMAET 230


>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
           [Homo sapiens]
          Length = 200

 Score = 68.6 bits (166), Expect = 5e-12
 Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 4/138 (2%)

Query: 1   MTSQPVPNETIIVLPSNVI--NFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMM 58
           M S    +   +V P  +    +   E    T   Q  L+K    ++K++GTIQIL G+M
Sbjct: 1   MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM 60

Query: 59  VLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSL 118
             S G+I       P + +     L S YPF G   FI SG+  IA +++ T+ L+  S 
Sbjct: 61  TFSFGVIFLFTLLKP-YPRFPFIFL-SGYPFWGSVLFINSGAFLIAVKRKTTETLIILSR 118

Query: 119 VGSILSALSALVGFIILS 136
           + + LSAL A+ G I+L+
Sbjct: 119 IMNFLSALGAIAGIILLT 136


>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
           isoform a [Homo sapiens]
          Length = 214

 Score = 68.2 bits (165), Expect = 6e-12
 Identities = 56/186 (30%), Positives = 85/186 (45%), Gaps = 23/186 (12%)

Query: 27  PEPTN----QGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQ-VTST 81
           PE  N    Q  D    +  A+++V+G IQIL   M+L+LG+ L S  +  +F +     
Sbjct: 26  PEELNTSVYQPIDGSPDYQKAKLQVLGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFF 85

Query: 82  LLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQAT 141
              + YP  G  FF  SG+LS+    + T+  + +S   +I SA  ALVG   LS+  A 
Sbjct: 86  TFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAV 145

Query: 142 LNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLA-GTLSLMLICTLLEFCLA 200
              +   C                 H S  + D      S++ G +SL+LI TLLE C+ 
Sbjct: 146 NIQSLRSC-----------------HSSSESPDLCNYMGSISNGMVSLLLILTLLELCVT 188

Query: 201 VLTAVL 206
           + T  +
Sbjct: 189 ISTIAM 194


>gi|149588599 membrane-spanning 4-domains, subfamily A, member 15
           isoform 1 [Homo sapiens]
          Length = 240

 Score = 67.8 bits (164), Expect = 8e-12
 Identities = 63/230 (27%), Positives = 98/230 (42%), Gaps = 44/230 (19%)

Query: 10  TIIVLPSNVINFSQ----AEKPEPTNQGQ-DSLKKHLHAEIKVIGTIQILCGMMVLSLGI 64
           T +  P  ++ F +    A+ P  T       ++  L  E KV+GT+QIL G++ L  G 
Sbjct: 31  TSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGS 90

Query: 65  ILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILS 124
           +L           V    +    PF G   FIISGSLS+A EK  T  LV SSL  +ILS
Sbjct: 91  VLLMVRRG----HVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILS 146

Query: 125 ALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAG 184
            ++A  G  IL +     N      ++D+                              G
Sbjct: 147 VMAAFAGTAILLMDFGVTNR-----DVDR------------------------------G 171

Query: 185 TLSLMLICTLLEFCLAVLTAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSS 234
            L+++ I T+LEF  AV+      +  ++     V+FLP+++  +  + S
Sbjct: 172 YLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPS 221


>gi|23110987 membrane-spanning 4-domains, subfamily A, member 1
           [Homo sapiens]
          Length = 297

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 51/192 (26%), Positives = 87/192 (45%), Gaps = 22/192 (11%)

Query: 44  EIKVIGTIQILCGMMVLSLG--IILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSL 101
           E K +G +QI+ G+  ++LG  +++ +  ++P    V        YP  G   +IISGSL
Sbjct: 48  ESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVW-------YPLWGGIMYIISGSL 100

Query: 102 SIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSY 161
             ATEK   K LV   ++ + LS  +A+ G +ILS+        S   +++  N   R++
Sbjct: 101 LAATEKNSRKCLVKGKMIMNSLSLFAAISG-MILSIMDILNIKISHFLKMESLNF-IRAH 158

Query: 162 VSYF-----------YHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQ 210
             Y              +S  T  CY+ ++   G LS+MLI    +  +        WK+
Sbjct: 159 TPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKR 218

Query: 211 AYSDFPGSVLFL 222
             S    +++ L
Sbjct: 219 TCSRPKSNIVLL 230


>gi|23110989 membrane-spanning 4-domains, subfamily A, member 1
           [Homo sapiens]
          Length = 297

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 51/192 (26%), Positives = 87/192 (45%), Gaps = 22/192 (11%)

Query: 44  EIKVIGTIQILCGMMVLSLG--IILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSL 101
           E K +G +QI+ G+  ++LG  +++ +  ++P    V        YP  G   +IISGSL
Sbjct: 48  ESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVW-------YPLWGGIMYIISGSL 100

Query: 102 SIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRSY 161
             ATEK   K LV   ++ + LS  +A+ G +ILS+        S   +++  N   R++
Sbjct: 101 LAATEKNSRKCLVKGKMIMNSLSLFAAISG-MILSIMDILNIKISHFLKMESLNF-IRAH 158

Query: 162 VSYF-----------YHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQ 210
             Y              +S  T  CY+ ++   G LS+MLI    +  +        WK+
Sbjct: 159 TPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKR 218

Query: 211 AYSDFPGSVLFL 222
             S    +++ L
Sbjct: 219 TCSRPKSNIVLL 230


>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
           isoform 1 [Homo sapiens]
          Length = 244

 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 44/161 (27%), Positives = 67/161 (41%), Gaps = 17/161 (10%)

Query: 41  LHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGS 100
           L  E + +G  QIL  M+ L  G ++ S     +      +   + YPF G  FF ISG 
Sbjct: 54  LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113

Query: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKNNIPTRS 160
           LSI +E+R    LV  SL  +  S+++   G  IL +                N   + +
Sbjct: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILII----------------NLKKSLA 157

Query: 161 YVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAV 201
           Y+        + T C+ A  S    + +ML  T+L    AV
Sbjct: 158 YIHIHSCQKFFETKCFMASFS-TEIVVMMLFLTILGLGSAV 197


>gi|22749421 membrane-spanning 4-domains, subfamily A, member 15
           isoform 2 [Homo sapiens]
          Length = 147

 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 43/152 (28%), Positives = 66/152 (43%), Gaps = 35/152 (23%)

Query: 83  LNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATL 142
           +    PF G   FIISGSLS+A EK  T  LV SSL  +ILS ++A  G  IL +     
Sbjct: 12  IEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVT 71

Query: 143 NPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVL 202
           N      ++D+                              G L+++ I T+LEF  AV+
Sbjct: 72  NR-----DVDR------------------------------GYLAVLTIFTVLEFFTAVI 96

Query: 203 TAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSS 234
                 +  ++     V+FLP+++  +  + S
Sbjct: 97  AMHFGCQAIHAQASAPVIFLPNAFSADFNIPS 128


>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
           isoform 2 [Homo sapiens]
          Length = 195

 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 32/97 (32%), Positives = 47/97 (48%)

Query: 41  LHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGS 100
           L  E + +G  QIL  M+ L  G ++ S     +      +   + YPF G  FF ISG 
Sbjct: 54  LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113

Query: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137
           LSI +E+R    LV  SL  +  S+++   G  IL +
Sbjct: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILII 150


>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
           [Homo sapiens]
          Length = 250

 Score = 51.2 bits (121), Expect = 8e-07
 Identities = 34/92 (36%), Positives = 52/92 (56%), Gaps = 5/92 (5%)

Query: 44  EIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSI 103
           E K +G IQI+ G+  + LG I+A+        +  S      +PF G  +FIISGSLS+
Sbjct: 68  EGKTLGAIQIIIGLAHIGLGSIMATVLVG----EYLSISFYGGFPFWGGLWFIISGSLSV 123

Query: 104 ATEKR-LTKLLVHSSLVGSILSALSALVGFII 134
           A E +  +  L+  SL  +I+SA+ + VG I+
Sbjct: 124 AAENQPYSYCLLSGSLGLNIVSAICSAVGVIL 155


>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
           isoform 1 [Homo sapiens]
          Length = 679

 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 34/105 (32%), Positives = 56/105 (53%), Gaps = 6/105 (5%)

Query: 36  SLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFF 95
           SL   L  E +V+G  QIL  ++++  G I A       F+Q    ++ + YPF G   F
Sbjct: 33  SLLDFLKGEPRVLGATQILLALIIVGFGTIFALNYIG--FSQRLPLVVLTGYPFWGALIF 90

Query: 96  IISGSLSIATEKRLTKLLVHSSLVGSILSALSALVG--FIILSVK 138
           I++G L++  +K  +KLL       +++S+L A+ G  F ILS +
Sbjct: 91  ILTGYLTVTDKK--SKLLGQGVTGMNVISSLVAITGITFTILSYR 133


>gi|169202868 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 48  IGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEK 107
           +GT  +   + +L +G+    ++ +P           S YP  G   +I+SGSLS+   K
Sbjct: 143 VGTASLQTAIQIL-IGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAK 201

Query: 108 RLTKLLVHSSLVGSILSALSALVGFIIL 135
             +  +V+SS+  +I+SAL A  G  I+
Sbjct: 202 DPSPCVVNSSISFNIISALFAFAGIFII 229


>gi|169203526 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 48  IGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEK 107
           +GT  +   + +L +G+    ++ +P           S YP  G   +I+SGSLS+   K
Sbjct: 143 VGTASLQTAIQIL-IGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAK 201

Query: 108 RLTKLLVHSSLVGSILSALSALVGFIIL 135
             +  +V+SS+  +I+SAL A  G  I+
Sbjct: 202 DPSPCVVNSSISFNIISALFAFAGIFII 229


>gi|169202217 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 48  IGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEK 107
           +GT  +   + +L +G+    ++ +P           S YP  G   +I+SGSLS+   K
Sbjct: 143 VGTASLQTAIQIL-IGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAK 201

Query: 108 RLTKLLVHSSLVGSILSALSALVGFIIL 135
             +  +V+SS+  +I+SAL A  G  I+
Sbjct: 202 DPSPCVVNSSISFNIISALFAFAGIFII 229


>gi|73486653 membrane-spanning 4-domains, subfamily A, member 3
           isoform b [Homo sapiens]
          Length = 168

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 18/113 (15%)

Query: 95  FIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQCELDKN 154
           F  SG+LS+    + T+  + +S   +I SA  ALVG   LS+  A    +   C     
Sbjct: 53  FCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSC----- 107

Query: 155 NIPTRSYVSYFYHDSLYTTDCYTAKASLA-GTLSLMLICTLLEFCLAVLTAVL 206
                       H S  + D      S++ G +SL+LI TLLE C+ + T  +
Sbjct: 108 ------------HSSSESPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAM 148


>gi|167466260 membrane-spanning 4-domains, subfamily A, member 10
           [Homo sapiens]
          Length = 267

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 37/195 (18%)

Query: 23  QAEKPEPTNQGQDSLKKHLHAE-------IKVIGTIQILCGMMVLSLGIILASASFSPNF 75
           Q   P+ T Q +  L  H H +       +K +G   I   ++ L  G  LAS       
Sbjct: 29  QTSAPQNTTQPK-LLAPHQHEKSQKKSSLLKELGAFHITIALLHLVFGGYLASI-----V 82

Query: 76  TQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135
             +   +L S YPF G   F+ISG L+I  +      L    L+ +++S    L G  ++
Sbjct: 83  KNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVI 142

Query: 136 SVKQATLNPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLIC-TL 194
           S K   L              P  S +   Y +S                L L L+C T+
Sbjct: 143 S-KDLFLES------------PFESPIWRMYPNSTVHIQ----------RLELALLCFTV 179

Query: 195 LEFCLAVLTAVLRWK 209
           LE  L V TAV  W+
Sbjct: 180 LELFLPVPTAVTAWR 194


>gi|16933561 sarcospan isoform 1 [Homo sapiens]
          Length = 243

 Score = 36.2 bits (82), Expect = 0.027
 Identities = 39/176 (22%), Positives = 72/176 (40%), Gaps = 13/176 (7%)

Query: 47  VIGTIQILCGMMVLSLGIILASASFS--PNFTQVTSTLLNSAYPFIGPFFFIISGSLSIA 104
           ++  +Q+  G+ V  +G ++AS S S     T   + ++     ++G F   +S  +   
Sbjct: 55  LLALLQLALGIAVTVVGFLMASISSSLLVRDTPFWAGIIVCLVAYLGLFMLCVSYQVDER 114

Query: 105 TEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPA-----SLQCELDKNNIPTR 159
           T  + +  L++  L    L+     V F      Q T         S QC+L  +   +R
Sbjct: 115 TCIQFSMKLLYFLLSALGLTVCVLAVAFAAHHYSQLTQFTCETTLDSCQCKLPSSEPLSR 174

Query: 160 SYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVLTAVLRWKQAYSDF 215
           ++V   Y D    TDC +   +    L + +I  L+   + +L   + WK  Y  F
Sbjct: 175 TFV---YRD---VTDCTSVTGTFKLFLLIQMILNLVCGLVCLLACFVMWKHRYQVF 224


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,583,263
Number of Sequences: 37866
Number of extensions: 324436
Number of successful extensions: 774
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 713
Number of HSP's gapped (non-prelim): 42
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.