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Search of human proteins with 228480211
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|228480211 four and a half LIM domains 1 isoform 1 [Homo
sapiens]
(323 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 721 0.0
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 525 e-149
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 525 e-149
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 525 e-149
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 525 e-149
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 525 e-149
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens] 387 e-108
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 286 2e-77
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 286 2e-77
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 286 2e-77
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 286 2e-77
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 259 2e-69
gi|30410801 activator of cAMP-responsive element modulator (CREM... 252 4e-67
gi|170932518 paxillin isoform 3 [Homo sapiens] 120 1e-27
gi|170932516 paxillin isoform 2 [Homo sapiens] 120 1e-27
gi|170932514 paxillin isoform 1 [Homo sapiens] 120 1e-27
gi|221316659 leupaxin isoform 1 [Homo sapiens] 107 1e-23
gi|4758670 leupaxin isoform 2 [Homo sapiens] 107 1e-23
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 103 2e-22
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 103 2e-22
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 103 2e-22
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 103 2e-22
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 103 2e-22
gi|109638745 transforming growth factor beta 1 induced transcrip... 101 8e-22
gi|21361591 transforming growth factor beta 1 induced transcript... 101 8e-22
gi|38524620 prickle-like 2 [Homo sapiens] 101 1e-21
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 99 5e-21
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 99 5e-21
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 96 4e-20
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens] 96 4e-20
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 721 bits (1861), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHP 240
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHP
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHP 240
Query: 241 VSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVK 300
VSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVK
Sbjct: 241 VSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVK 300
Query: 301 APVWWPMKDNPGTTTASTAKNAP 323
APVWWPMKDNPGTTTASTAKNAP
Sbjct: 301 APVWWPMKDNPGTTTASTAKNAP 323
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 525 bits (1351), Expect = e-149
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
Score = 150 bits (380), Expect = 1e-36
Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C PL + +V KD C KC + + C C K I A + V YK WH
Sbjct: 66 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C+ C + +F K C C + + C C KAI +G + Y+ WH
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
DCF C C + + F + +YCV C++ AK C C IT G + Y+ Q
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 243
Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
WH CF C CS LA +RF ++Q YC DC K
Sbjct: 244 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278
Score = 73.9 bits (180), Expect = 2e-13
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
A+ F C C L G+++ + + C+ C+ F A C C+ PI G S V Y+
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 242
Query: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
+ WHD CF C KC LAN+ FV ++ C C +
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 525 bits (1351), Expect = e-149
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
Score = 150 bits (380), Expect = 1e-36
Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C PL + +V KD C KC + + C C K I A + V YK WH
Sbjct: 66 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C+ C + +F K C C + + C C KAI +G + Y+ WH
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
DCF C C + + F + +YCV C++ AK C C IT G + Y+ Q
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 243
Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
WH CF C CS LA +RF ++Q YC DC K
Sbjct: 244 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278
Score = 73.9 bits (180), Expect = 2e-13
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
A+ F C C L G+++ + + C+ C+ F A C C+ PI G S V Y+
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 242
Query: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
+ WHD CF C KC LAN+ FV ++ C C +
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 525 bits (1351), Expect = e-149
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 30 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 89
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 90 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 149
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 209
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 210 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 259
Score = 150 bits (380), Expect = 1e-36
Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C PL + +V KD C KC + + C C K I A + V YK WH
Sbjct: 95 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 154
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C+ C + +F K C C + + C C KAI +G + Y+ WH
Sbjct: 155 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 212
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
DCF C C + + F + +YCV C++ AK C C IT G + Y+ Q
Sbjct: 213 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 272
Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
WH CF C CS LA +RF ++Q YC DC K
Sbjct: 273 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 307
Score = 73.9 bits (180), Expect = 2e-13
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
A+ F C C L G+++ + + C+ C+ F A C C+ PI G S V Y+
Sbjct: 212 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 271
Query: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
+ WHD CF C KC LAN+ FV ++ C C +
Sbjct: 272 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 308
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 525 bits (1351), Expect = e-149
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 246
Score = 150 bits (380), Expect = 1e-36
Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C PL + +V KD C KC + + C C K I A + V YK WH
Sbjct: 82 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 141
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C+ C + +F K C C + + C C KAI +G + Y+ WH
Sbjct: 142 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 199
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
DCF C C + + F + +YCV C++ AK C C IT G + Y+ Q
Sbjct: 200 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 259
Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
WH CF C CS LA +RF ++Q YC DC K
Sbjct: 260 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 294
Score = 73.9 bits (180), Expect = 2e-13
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
A+ F C C L G+++ + + C+ C+ F A C C+ PI G S V Y+
Sbjct: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 258
Query: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
+ WHD CF C KC LAN+ FV ++ C C +
Sbjct: 259 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 525 bits (1351), Expect = e-149
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
Score = 150 bits (380), Expect = 1e-36
Identities = 74/215 (34%), Positives = 98/215 (45%), Gaps = 7/215 (3%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C PL + +V KD C KC + + C C K I A + V YK WH
Sbjct: 66 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C+ C + +F K C C + + C C KAI +G + Y+ WH
Sbjct: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG-----ITYQDQ 179
DCF C C + + F + +YCV C++ AK C C IT G + Y+ Q
Sbjct: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEGQ 243
Query: 180 PWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK 214
WH CF C CS LA +RF ++Q YC DC K
Sbjct: 244 SWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278
Score = 73.9 bits (180), Expect = 2e-13
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI---GADSKEVHYKN 58
A+ F C C L G+++ + + C+ C+ F A C C+ PI G S V Y+
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAYEG 242
Query: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
+ WHD CF C KC LAN+ FV ++ C C +
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279
>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
Length = 194
Score = 387 bits (994), Expect = e-108
Identities = 169/182 (92%), Positives = 173/182 (95%), Gaps = 2/182 (1%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY--QD 178
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK + + + +D
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
Query: 179 QP 180
P
Sbjct: 181 NP 182
Score = 109 bits (272), Expect = 4e-24
Identities = 52/161 (32%), Positives = 71/161 (44%), Gaps = 2/161 (1%)
Query: 66 FRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKD 125
F C C PL + +V KD C KC + + C C K I A + V YK WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 126 CFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSG--GITYQDQPWHA 183
CF C+ C + +F K C C + + C C KAI +G + Y+ WH
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
Query: 184 DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGC 224
DCF C C + + F + +YCV C++ AK C C
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165
Score = 100 bits (249), Expect = 2e-21
Identities = 67/206 (32%), Positives = 87/206 (42%), Gaps = 25/206 (12%)
Query: 127 FTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHAD 184
F C C+ + + K C+ C + A CV+C K I S + Y+++ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG-------KRTVSRV 237
CF C C LA + F A +++ C C + KC GC I K TV
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
Query: 238 SHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPG 297
K + G P G + C + + K+ G
Sbjct: 125 DCFTCSNCKQVIGTGSFFP-------------KGEDFYCVTCHETKFAKH---CVKCNKG 168
Query: 298 LVKAPVWWPMKDNPGTTTASTAKNAP 323
LVKAPVWWPMKDNPGTTTASTAKNAP
Sbjct: 169 LVKAPVWWPMKDNPGTTTASTAKNAP 194
Score = 37.7 bits (86), Expect = 0.014
Identities = 14/46 (30%), Positives = 23/46 (50%)
Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPI 228
A+ F C C L G+++ + + C+ C+ F A C C+ PI
Sbjct: 2 AEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPI 47
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 286 bits (731), Expect = 2e-77
Identities = 116/230 (50%), Positives = 162/230 (70%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230
Score = 162 bits (409), Expect = 5e-40
Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C CR+ L K + K+ C C+ ++ C EC+K I ++++ YK WH+T
Sbjct: 66 FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C +C P+ ++F+ KDN+ C C ++ + +C C K I G V Y+ WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
+CF C+ C++ + F + + YC+ C +AK C C I+ G I+++++
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
WH DCF C CS L G+ F D C DC K+
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 286 bits (731), Expect = 2e-77
Identities = 116/230 (50%), Positives = 162/230 (70%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230
Score = 162 bits (409), Expect = 5e-40
Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C CR+ L K + K+ C C+ ++ C EC+K I ++++ YK WH+T
Sbjct: 66 FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C +C P+ ++F+ KDN+ C C ++ + +C C K I G V Y+ WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
+CF C+ C++ + F + + YC+ C +AK C C I+ G I+++++
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
WH DCF C CS L G+ F D C DC K+
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 286 bits (731), Expect = 2e-77
Identities = 116/230 (50%), Positives = 162/230 (70%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230
Score = 162 bits (409), Expect = 5e-40
Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C CR+ L K + K+ C C+ ++ C EC+K I ++++ YK WH+T
Sbjct: 66 FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C +C P+ ++F+ KDN+ C C ++ + +C C K I G V Y+ WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
+CF C+ C++ + F + + YC+ C +AK C C I+ G I+++++
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
WH DCF C CS L G+ F D C DC K+
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 286 bits (731), Expect = 2e-77
Identities = 116/230 (50%), Positives = 162/230 (70%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
M E+FDCH+C + L GKKY+ ++ C+ CF+ ANTC EC KPIG D K++ YK+R
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WH+ CF C++C + L ++ F AK++++LC C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
WH+ CF C C+Q IGT SF PK +CV C+E + A CV+C K IT+GG+TY++QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WH +CFVC C K+L+GQRFTA +D YC++C+ + AKKCAGC NPI+G
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230
Score = 162 bits (409), Expect = 5e-40
Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C CR+ L K + K+ C C+ ++ C EC+K I ++++ YK WH+T
Sbjct: 66 FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C +C P+ ++F+ KDN+ C C ++ + +C C K I G V Y+ WHK
Sbjct: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
+CF C+ C++ + F + + YC+ C +AK C C I+ G I+++++
Sbjct: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
WH DCF C CS L G+ F D C DC K+
Sbjct: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 259 bits (662), Expect = 2e-69
Identities = 105/230 (45%), Positives = 148/230 (64%)
Query: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
M+E FDC C + L G+KY+Q D C+ C+D ANTC EC++ IG DS+E+ Y++R
Sbjct: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
+H+ CFRC +C LA+E F +D+++LCN C S +C C + ++ G + +EY G
Sbjct: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
WH+ CF CS C+Q +G+ SF P YCV C+E KFA C +C+K +T GG+TY+DQP
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
WH +C VC C LAGQ+FT+ ++ YCV C+ A KC+ CK PI G
Sbjct: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVG 230
Score = 140 bits (353), Expect = 2e-33
Identities = 64/212 (30%), Positives = 99/212 (46%), Gaps = 6/212 (2%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C+ L + + +D C C+ ++ C C + + S+++ Y + WH+
Sbjct: 66 FRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEH 125
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF C+ C PL + +FV C C + +P+C C K + G V Y+ WH+
Sbjct: 126 CFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQG--GVTYRDQPWHR 183
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
+C C+ C+ + F + ED YCV C FA C C + I G ++++D+
Sbjct: 184 ECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRH 243
Query: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDC 212
WH +CF C CS L GQ F DQ C C
Sbjct: 244 WHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
Score = 100 bits (248), Expect = 2e-21
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C PL + +V G H C+ C++ A C C K + V Y+++ WH
Sbjct: 127 FLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGG--VTYRDQPWHRE 184
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA--GDQNVEYKGTVW 122
C C C PLA + F ++D C C +PKC C + IV G + V ++ W
Sbjct: 185 CLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHW 244
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 155
H +CF+C+ C + F P G+ C C +
Sbjct: 245 HHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
>gi|30410801 activator of cAMP-responsive element modulator (CREM)
in testis [Homo sapiens]
Length = 284
Score = 252 bits (643), Expect = 4e-67
Identities = 106/226 (46%), Positives = 142/226 (62%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C YC L GKKYV KD C+ C+D+ +N C EC+KPI +DSK++ YK+R WH+
Sbjct: 6 FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
CF+C KC H L + F AKD ++LC +C + E S KC C + I+ G + +E+KG WH+
Sbjct: 66 CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
Query: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHAD 184
CF C NC+Q IGT K YCV C E +FA +C C K ITSGGIT+ DQ WH +
Sbjct: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
Query: 185 CFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
CF+C C K L ++F + +D +C+DCY + A KC C PI+G
Sbjct: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISG 231
Score = 73.2 bits (178), Expect = 3e-13
Identities = 32/98 (32%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60
E F C CR L ++++ +D + C+ C++ AN CV C KPI +K + +++
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
WH CF C KC L + F+ ++ +I C KC + D+
Sbjct: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDT 282
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 120 bits (302), Expect = 1e-27
Identities = 67/211 (31%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E F C +C++ + + + ++DG C K + + C C PI K V +R WH
Sbjct: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 270
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
F CA+C E F KD K C K +PKC GC +AI+ + + T+W
Sbjct: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 328
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
H +CF C C GSFF YC + + C C K IT IT + +H
Sbjct: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
+ FVC C K+L F D+ YC +C+
Sbjct: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 419
Score = 101 bits (251), Expect = 1e-21
Identities = 60/203 (29%), Positives = 84/203 (41%), Gaps = 6/203 (2%)
Query: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
C C+KPI + V + WH F C C + + F +D + C K SP
Sbjct: 191 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248
Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
+C C I+ D+ V WH + F C+ C G F K YC + FA
Sbjct: 249 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
C C +AI I+ + WH +CFVC C F + Q YC Y
Sbjct: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
C+GC+ PITG+ +++ HP
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHP 389
Score = 30.0 bits (66), Expect = 2.9
Identities = 22/82 (26%), Positives = 28/82 (34%), Gaps = 28/82 (34%)
Query: 187 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 220
VC C K +AGQ TA+ + Q YC Y N + +
Sbjct: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
Query: 221 CAGCKNPITGK--RTVSRVSHP 240
C C PI K + R HP
Sbjct: 250 CYYCNGPILDKVVTALDRTWHP 271
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 120 bits (302), Expect = 1e-27
Identities = 67/211 (31%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E F C +C++ + + + ++DG C K + + C C PI K V +R WH
Sbjct: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 403
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
F CA+C E F KD K C K +PKC GC +AI+ + + T+W
Sbjct: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 461
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
H +CF C C GSFF YC + + C C K IT IT + +H
Sbjct: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
+ FVC C K+L F D+ YC +C+
Sbjct: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 552
Score = 101 bits (251), Expect = 1e-21
Identities = 60/203 (29%), Positives = 84/203 (41%), Gaps = 6/203 (2%)
Query: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
C C+KPI + V + WH F C C + + F +D + C K SP
Sbjct: 324 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381
Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
+C C I+ D+ V WH + F C+ C G F K YC + FA
Sbjct: 382 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
C C +AI I+ + WH +CFVC C F + Q YC Y
Sbjct: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
C+GC+ PITG+ +++ HP
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHP 522
Score = 30.0 bits (66), Expect = 2.9
Identities = 22/82 (26%), Positives = 28/82 (34%), Gaps = 28/82 (34%)
Query: 187 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 220
VC C K +AGQ TA+ + Q YC Y N + +
Sbjct: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
Query: 221 CAGCKNPITGK--RTVSRVSHP 240
C C PI K + R HP
Sbjct: 383 CYYCNGPILDKVVTALDRTWHP 404
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 120 bits (302), Expect = 1e-27
Identities = 67/211 (31%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E F C +C++ + + + ++DG C K + + C C PI K V +R WH
Sbjct: 380 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 437
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
F CA+C E F KD K C K +PKC GC +AI+ + + T+W
Sbjct: 438 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 495
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
H +CF C C GSFF YC + + C C K IT IT + +H
Sbjct: 496 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 555
Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
+ FVC C K+L F D+ YC +C+
Sbjct: 556 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 586
Score = 101 bits (251), Expect = 1e-21
Identities = 60/203 (29%), Positives = 84/203 (41%), Gaps = 6/203 (2%)
Query: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
C C+KPI + V + WH F C C + + F +D + C K SP
Sbjct: 358 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 415
Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
+C C I+ D+ V WH + F C+ C G F K YC + FA
Sbjct: 416 RCYYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 473
Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
C C +AI I+ + WH +CFVC C F + Q YC Y
Sbjct: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533
Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
C+GC+ PITG+ +++ HP
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHP 556
Score = 30.0 bits (66), Expect = 2.9
Identities = 22/82 (26%), Positives = 28/82 (34%), Gaps = 28/82 (34%)
Query: 187 VCVTCSKKLAGQRFTAV--------------------------EDQYYCVDCYKNFVAKK 220
VC C K +AGQ TA+ + Q YC Y N + +
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416
Query: 221 CAGCKNPITGK--RTVSRVSHP 240
C C PI K + R HP
Sbjct: 417 CYYCNGPILDKVVTALDRTWHP 438
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 107 bits (267), Expect = 1e-23
Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E F C +C++ + + ++ G C + + + C C PI K + N+ WH
Sbjct: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWH 236
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
F C+ C E F KD K C K SPKC GC + ++ + + TVW
Sbjct: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
H +CF C +C TGSFF +C + + C C + IT I+ +H
Sbjct: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
+ FVC C +L+ F D+ YC C+
Sbjct: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
Score = 103 bits (258), Expect = 2e-22
Identities = 54/192 (28%), Positives = 82/192 (42%), Gaps = 4/192 (2%)
Query: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
C C+KPI K +H + WH F C C + + F + C + SP
Sbjct: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
+C C I+ D+ + WH + F CS+C +V G F K + YC F+
Sbjct: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
C CN+ + ++ D WH +CFVC C + F ++ + +C Y +
Sbjct: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
Query: 220 KCAGCKNPITGK 231
C GC PITG+
Sbjct: 333 LCHGCGQPITGR 344
Score = 60.8 bits (146), Expect = 2e-09
Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E F C +C + + + +KD C K F + C C +P+ + + WH
Sbjct: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 295
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
CF C C + +F D + C C GC + I + + G +
Sbjct: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 353
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
H + F C+ C + G F + + YC C F
Sbjct: 354 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
Score = 50.8 bits (120), Expect = 2e-06
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
HC C K I I Q WH + FVC C +++ F YC + Y + +
Sbjct: 156 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 215
Query: 221 CAGCKNPITGK--RTVSRVSHP 240
CA C PI K +++ HP
Sbjct: 216 CAYCAAPILDKVLTAMNQTWHP 237
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 107 bits (267), Expect = 1e-23
Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E F C +C++ + + ++ G C + + + C C PI K + N+ WH
Sbjct: 174 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWH 231
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
F C+ C E F KD K C K SPKC GC + ++ + + TVW
Sbjct: 232 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 289
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
H +CF C +C TGSFF +C + + C C + IT I+ +H
Sbjct: 290 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 349
Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
+ FVC C +L+ F D+ YC C+
Sbjct: 350 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 380
Score = 103 bits (258), Expect = 2e-22
Identities = 54/192 (28%), Positives = 82/192 (42%), Gaps = 4/192 (2%)
Query: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
C C+KPI K +H + WH F C C + + F + C + SP
Sbjct: 152 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209
Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
+C C I+ D+ + WH + F CS+C +V G F K + YC F+
Sbjct: 210 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267
Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
C CN+ + ++ D WH +CFVC C + F ++ + +C Y +
Sbjct: 268 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 327
Query: 220 KCAGCKNPITGK 231
C GC PITG+
Sbjct: 328 LCHGCGQPITGR 339
Score = 60.8 bits (146), Expect = 2e-09
Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E F C +C + + + +KD C K F + C C +P+ + + WH
Sbjct: 233 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 290
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
CF C C + +F D + C C GC + I + + G +
Sbjct: 291 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 348
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
H + F C+ C + G F + + YC C F
Sbjct: 349 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
Score = 50.8 bits (120), Expect = 2e-06
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
HC C K I I Q WH + FVC C +++ F YC + Y + +
Sbjct: 151 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 210
Query: 221 CAGCKNPITGK--RTVSRVSHP 240
CA C PI K +++ HP
Sbjct: 211 CAYCAAPILDKVLTAMNQTWHP 232
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 103 bits (258), Expect = 2e-22
Identities = 65/232 (28%), Positives = 91/232 (39%), Gaps = 12/232 (5%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C + + +G C F A C +C + I + + N WH
Sbjct: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
CFRC C LA+ FV + LC C RE K +G K I + +Q + +K
Sbjct: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 150
Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
+H D F C+NC + + + KGE YC+ CH+ C C + I +
Sbjct: 151 NDPYHPDHFNCANCGKELTADARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNAMG 209
Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
+ WH + FVC C K G R + YC Y C C I G
Sbjct: 210 KQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG 261
Score = 97.8 bits (242), Expect = 1e-20
Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 8/198 (4%)
Query: 39 TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
TC C+ K V+ +H+ CF CA+C F + + C +
Sbjct: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68
Query: 99 PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
P C C + I+ + ++ WH +CF C C++V+ F C CH +
Sbjct: 69 PCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
Query: 159 AKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
A+ C KC+ I + +++ P+H D F C C K+L ++ + YC+ C+
Sbjct: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCH 185
Query: 214 KNFVAKKCAGCKNPITGK 231
C C+ PI G+
Sbjct: 186 DKMGVPICGACRRPIEGR 203
Score = 92.8 bits (229), Expect = 4e-19
Identities = 62/221 (28%), Positives = 95/221 (42%), Gaps = 13/221 (5%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57
E F C C++ L +V+ G H C C ++ A C +C I D + + +K
Sbjct: 93 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 150
Query: 58 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
N +H F CA C L + K ++ C C + P C C + I + V
Sbjct: 151 NDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNA 207
Query: 118 KGTVWHKDCFTCSNC-KQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY 176
G WH + F C+ C K +G + KG YC T + F C CN+ I ++
Sbjct: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGLA-YCETHYNQLFGDVCFHCNRVIEGDVVSA 266
Query: 177 QDQPWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNF 216
++ W +CF C TC+ KL +F + + C CY+ F
Sbjct: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307
Score = 65.1 bits (157), Expect = 8e-11
Identities = 34/132 (25%), Positives = 54/132 (40%), Gaps = 8/132 (6%)
Query: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
S C+ C ++ V G ++H+ CF C+ C Q G F+ YC +
Sbjct: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
Query: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYK--- 214
FA C +C + I I + WH +CF C C + LA F ++ C C+
Sbjct: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
Query: 215 -----NFVAKKC 221
++ +KC
Sbjct: 127 ARGLGKYICQKC 138
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 103 bits (257), Expect = 2e-22
Identities = 66/232 (28%), Positives = 92/232 (39%), Gaps = 12/232 (5%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C P + + +G C F A C C + I + + N WH
Sbjct: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 177
Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 178 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 236
Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
+ WH + FVC C K G R + YC Y C C + I G
Sbjct: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG 288
Score = 88.6 bits (218), Expect = 7e-18
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 8/204 (3%)
Query: 33 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 30 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 89
Query: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 90 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
Query: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 206
Query: 208 YCVDCYKNFVAKKCAGCKNPITGK 231
YC+ C+ C C+ PI G+
Sbjct: 207 YCLPCHDKMGVPICGACRRPIEGR 230
Score = 85.5 bits (210), Expect = 6e-17
Identities = 60/249 (24%), Positives = 98/249 (39%), Gaps = 21/249 (8%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYKNR 59
F C C L +V+ G H C C ++ A C C I D + + +++
Sbjct: 122 FRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRSD 179
Query: 60 FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 119
+H F C C L E K ++ C C + P C C + I + V G
Sbjct: 180 AYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNALG 236
Query: 120 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 179
WH + F C+ C++ + K YC T + F C C+ I ++ ++
Sbjct: 237 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNK 296
Query: 180 PWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVS 238
W CF C TC+ KL +F + + C CY+ F P+ K+ + ++S
Sbjct: 297 AWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF----------PLELKKRLKKLS 346
Query: 239 HPVSKARKP 247
S+ +P
Sbjct: 347 ELTSRKAQP 355
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 103 bits (257), Expect = 2e-22
Identities = 66/232 (28%), Positives = 92/232 (39%), Gaps = 12/232 (5%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C P + + +G C F A C C + I + + N WH
Sbjct: 36 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 93
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 94 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 150
Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 151 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 209
Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
+ WH + FVC C K G R + YC Y C C + I G
Sbjct: 210 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG 261
Score = 88.6 bits (218), Expect = 7e-18
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 8/204 (3%)
Query: 33 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 3 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 62
Query: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 63 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 120
Query: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 121 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 179
Query: 208 YCVDCYKNFVAKKCAGCKNPITGK 231
YC+ C+ C C+ PI G+
Sbjct: 180 YCLPCHDKMGVPICGACRRPIEGR 203
Score = 85.5 bits (210), Expect = 6e-17
Identities = 60/249 (24%), Positives = 98/249 (39%), Gaps = 21/249 (8%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYKNR 59
F C C L +V+ G H C C ++ A C C I D + + +++
Sbjct: 95 FRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRSD 152
Query: 60 FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 119
+H F C C L E K ++ C C + P C C + I + V G
Sbjct: 153 AYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNALG 209
Query: 120 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 179
WH + F C+ C++ + K YC T + F C C+ I ++ ++
Sbjct: 210 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNK 269
Query: 180 PWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVS 238
W CF C TC+ KL +F + + C CY+ F P+ K+ + ++S
Sbjct: 270 AWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF----------PLELKKRLKKLS 319
Query: 239 HPVSKARKP 247
S+ +P
Sbjct: 320 ELTSRKAQP 328
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 103 bits (257), Expect = 2e-22
Identities = 66/232 (28%), Positives = 92/232 (39%), Gaps = 12/232 (5%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C P + + +G C F A C C + I + + N WH
Sbjct: 41 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 98
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 99 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 155
Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 156 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 214
Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
+ WH + FVC C K G R + YC Y C C + I G
Sbjct: 215 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG 266
Score = 88.6 bits (218), Expect = 7e-18
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 8/204 (3%)
Query: 33 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 8 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 67
Query: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 68 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 125
Query: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 126 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 184
Query: 208 YCVDCYKNFVAKKCAGCKNPITGK 231
YC+ C+ C C+ PI G+
Sbjct: 185 YCLPCHDKMGVPICGACRRPIEGR 208
Score = 85.5 bits (210), Expect = 6e-17
Identities = 60/249 (24%), Positives = 98/249 (39%), Gaps = 21/249 (8%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYKNR 59
F C C L +V+ G H C C ++ A C C I D + + +++
Sbjct: 100 FRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRSD 157
Query: 60 FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 119
+H F C C L E K ++ C C + P C C + I + V G
Sbjct: 158 AYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNALG 214
Query: 120 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 179
WH + F C+ C++ + K YC T + F C C+ I ++ ++
Sbjct: 215 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNK 274
Query: 180 PWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVS 238
W CF C TC+ KL +F + + C CY+ F P+ K+ + ++S
Sbjct: 275 AWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF----------PLELKKRLKKLS 324
Query: 239 HPVSKARKP 247
S+ +P
Sbjct: 325 ELTSRKAQP 333
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 103 bits (257), Expect = 2e-22
Identities = 66/232 (28%), Positives = 92/232 (39%), Gaps = 12/232 (5%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C P + + +G C F A C C + I + + N WH
Sbjct: 65 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 122
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
CFRC C LA+ FV + LC C RE K KG K I V +Q + ++
Sbjct: 123 CFRCELCDVELADLGFVKNAGRHLCRPCHNRE---KAKGLGKYICQRCHLVIDEQPLMFR 179
Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
+H D F C++C + + + KGE YC+ CH+ C C + I +
Sbjct: 180 SDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNALG 238
Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
+ WH + FVC C K G R + YC Y C C + I G
Sbjct: 239 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG 290
Score = 88.6 bits (218), Expect = 7e-18
Identities = 47/204 (23%), Positives = 78/204 (38%), Gaps = 8/204 (3%)
Query: 33 DKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92
D C C+ + V+ +H+ CF CA+C P F + + C
Sbjct: 32 DALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHD 91
Query: 93 TTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVT 152
+P C C + I+ + ++ WH CF C C + F C
Sbjct: 92 FQMLFAPCCGSCGEFIIG--RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 149
Query: 153 CHETKFAKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
CH + AK C +C+ I + ++ +H D F C C K+L + ++ +
Sbjct: 150 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGEL 208
Query: 208 YCVDCYKNFVAKKCAGCKNPITGK 231
YC+ C+ C C+ PI G+
Sbjct: 209 YCLPCHDKMGVPICGACRRPIEGR 232
Score = 85.5 bits (210), Expect = 6e-17
Identities = 60/249 (24%), Positives = 98/249 (39%), Gaps = 21/249 (8%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYKNR 59
F C C L +V+ G H C C ++ A C C I D + + +++
Sbjct: 124 FRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRSD 181
Query: 60 FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKG 119
+H F C C L E K ++ C C + P C C + I + V G
Sbjct: 182 AYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNALG 238
Query: 120 TVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQ 179
WH + F C+ C++ + K YC T + F C C+ I ++ ++
Sbjct: 239 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNK 298
Query: 180 PWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVS 238
W CF C TC+ KL +F + + C CY+ F P+ K+ + ++S
Sbjct: 299 AWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKF----------PLELKKRLKKLS 348
Query: 239 HPVSKARKP 247
S+ +P
Sbjct: 349 ELTSRKAQP 357
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 101 bits (252), Expect = 8e-22
Identities = 57/211 (27%), Positives = 85/211 (40%), Gaps = 4/211 (1%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E F C C L G + +KDG C +C+ + + C C +PI K V WH
Sbjct: 250 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIR--HKMVTALGTHWH 307
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
F C C P +E F ++ + C + + +P+C+GC I+ D + +W
Sbjct: 308 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 365
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
H DCF C C GSFF C + C C +T ++ + +H
Sbjct: 366 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 425
Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
D F C C + L F + YC C+
Sbjct: 426 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 456
Score = 96.7 bits (239), Expect = 3e-20
Identities = 62/203 (30%), Positives = 80/203 (39%), Gaps = 6/203 (2%)
Query: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
C C KPI + V R WH F C C L +F KD C +C SP
Sbjct: 228 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 285
Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
+C C + I + V GT WH + F C +C + G F + YC FA
Sbjct: 286 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343
Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
C C I I+ WH DCFVC C +G F E + C + +
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403
Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
CA C P+TG+ + R HP
Sbjct: 404 LCATCGLPVTGRCVSALGRRFHP 426
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 101 bits (252), Expect = 8e-22
Identities = 57/211 (27%), Positives = 85/211 (40%), Gaps = 4/211 (1%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E F C C L G + +KDG C +C+ + + C C +PI K V WH
Sbjct: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIR--HKMVTALGTHWH 290
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
F C C P +E F ++ + C + + +P+C+GC I+ D + +W
Sbjct: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 348
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182
H DCF C C GSFF C + C C +T ++ + +H
Sbjct: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 408
Query: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
D F C C + L F + YC C+
Sbjct: 409 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
Score = 96.7 bits (239), Expect = 3e-20
Identities = 62/203 (30%), Positives = 80/203 (39%), Gaps = 6/203 (2%)
Query: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
C C KPI + V R WH F C C L +F KD C +C SP
Sbjct: 211 CGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268
Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
+C C + I + V GT WH + F C +C + G F + YC FA
Sbjct: 269 RCGFCNQPI--RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
Query: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219
C C I I+ WH DCFVC C +G F E + C + +
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
Query: 220 KCAGCKNPITGK--RTVSRVSHP 240
CA C P+TG+ + R HP
Sbjct: 387 LCATCGLPVTGRCVSALGRRFHP 409
>gi|38524620 prickle-like 2 [Homo sapiens]
Length = 844
Score = 101 bits (251), Expect = 1e-21
Identities = 68/249 (27%), Positives = 105/249 (42%), Gaps = 14/249 (5%)
Query: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
WH CF C C L + + +D KI C + P+C C + I A D+ E +G
Sbjct: 155 WHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFA-DECTEAEGR 213
Query: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK--AITSGGITYQD 178
WH F C C+ V+G + K YC C E+ +A++C C + I G +TY
Sbjct: 214 HWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDG 273
Query: 179 QPWHA--DCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSR 236
Q WHA CF C C K L G+ F + Q +C ++ C+ ++P + S
Sbjct: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFC--------SRACSAGEDPNGSDSSDSA 325
Query: 237 VSHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLA-APRG 295
+ +K + GK T P N + + V L + L+ + +
Sbjct: 326 FQNARAKESRRSAKIGKNKGKTEEPMLNQHSQLQVSSNRLSADVDPLSLQMDMLSLSSQT 385
Query: 296 PGLVKAPVW 304
P L + P+W
Sbjct: 386 PSLNRDPIW 394
Score = 73.9 bits (180), Expect = 2e-13
Identities = 34/96 (35%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH-- 62
F C C L G++Y+ K+G C CF+ A C C + IG D ++ Y + WH
Sbjct: 220 FCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHAT 279
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNK-CTTRED 97
+TCF CA C L F+ K +I C++ C+ ED
Sbjct: 280 ETCFCCAHCKKSLLGRPFLPKQGQIFCSRACSAGED 315
Score = 70.1 bits (170), Expect = 3e-12
Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 5/133 (3%)
Query: 101 CKGCFKAIVAGDQNVEYK----GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156
C+ C I GD V G WH CF C+ C +++ +F + YC H
Sbjct: 130 CEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAE 189
Query: 157 KFAKHCVKCNKAITSGGIT-YQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
C C++ I + T + + WH F C C L GQR+ E + YC C+++
Sbjct: 190 CLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFES 249
Query: 216 FVAKKCAGCKNPI 228
A+ C C I
Sbjct: 250 LYAEYCDTCAQHI 262
Score = 63.9 bits (154), Expect = 2e-10
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C + L Y +DG C + + C C + I AD + R WH
Sbjct: 160 FVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADEC-TEAEGRHWHMK 218
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWH- 123
F C +C L + ++ K+ + C C + C C + I + Y G WH
Sbjct: 219 HFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHA 278
Query: 124 -KDCFTCSNCKQVIGTGSFFPKGEDFYC 150
+ CF C++CK+ + F PK +C
Sbjct: 279 TETCFCCAHCKKSLLGRPFLPKQGQIFC 306
Score = 31.2 bits (69), Expect = 1.3
Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 8/54 (14%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKN 58
F C +C+ L G+ ++ K G FC+ C P G+DS + ++N
Sbjct: 283 FCCAHCKKSLLGRPFLPKQGQI--------FCSRACSAGEDPNGSDSSDSAFQN 328
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 99.0 bits (245), Expect = 5e-21
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E+F C YC+ L +V++ + C +C+++F A C +C I + +H + WH
Sbjct: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
TCF CA C P N F +D + C K S KC GC + AGD+ +E G W
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
H CF C+ C + F+ K + C
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 89.4 bits (220), Expect = 4e-18
Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 4/153 (2%)
Query: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 118
R WH F CA C LA+ FV + N + C +C + +P C C I+ + +
Sbjct: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 515
Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITY 176
WH CF C+ CK+ G F + + YC + F+ C C+ + +G I
Sbjct: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
Query: 177 QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
WH CF+C C L GQ F + +D+ C
Sbjct: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 87.8 bits (216), Expect = 1e-17
Identities = 41/122 (33%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
G WH + FTC+ CK + F + + YC C+E FA C KCN I +
Sbjct: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPI-TGKRTVSRV 237
Q WH CFVC C K F + + YC Y N + KC GC P+ G + + +
Sbjct: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEAL 576
Query: 238 SH 239
H
Sbjct: 577 GH 578
Score = 58.5 bits (140), Expect = 8e-09
Identities = 28/87 (32%), Positives = 39/87 (44%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C+ P + +DG C K + + C C P+ A K + WHDT
Sbjct: 524 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 583
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNK 91
CF CA C L + F +K ++ LC K
Sbjct: 584 CFICAVCHVNLEGQPFYSKKDRPLCKK 610
Score = 52.8 bits (125), Expect = 4e-07
Identities = 23/70 (32%), Positives = 30/70 (42%)
Query: 162 CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 221
C CN I + + WH + F C C LA F ++ YC CY+ F A C
Sbjct: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
Query: 222 AGCKNPITGK 231
A C I G+
Sbjct: 501 AKCNTKIMGE 510
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 99.0 bits (245), Expect = 5e-21
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)
Query: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
E+F C YC+ L +V++ + C +C+++F A C +C I + +H + WH
Sbjct: 573 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 630
Query: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
TCF CA C P N F +D + C K S KC GC + AGD+ +E G W
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690
Query: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
H CF C+ C + F+ K + C
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 89.4 bits (220), Expect = 4e-18
Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 4/153 (2%)
Query: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 118
R WH F CA C LA+ FV + N + C +C + +P C C I+ + +
Sbjct: 568 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 625
Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITY 176
WH CF C+ CK+ G F + + YC + F+ C C+ + +G I
Sbjct: 626 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 685
Query: 177 QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
WH CF+C C L GQ F + +D+ C
Sbjct: 686 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 87.8 bits (216), Expect = 1e-17
Identities = 41/122 (33%), Positives = 55/122 (45%), Gaps = 1/122 (0%)
Query: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
G WH + FTC+ CK + F + + YC C+E FA C KCN I +
Sbjct: 567 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 626
Query: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPI-TGKRTVSRV 237
Q WH CFVC C K F + + YC Y N + KC GC P+ G + + +
Sbjct: 627 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEAL 686
Query: 238 SH 239
H
Sbjct: 687 GH 688
Score = 58.5 bits (140), Expect = 8e-09
Identities = 28/87 (32%), Positives = 39/87 (44%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C+ P + +DG C K + + C C P+ A K + WHDT
Sbjct: 634 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 693
Query: 65 CFRCAKCLHPLANETFVAKDNKILCNK 91
CF CA C L + F +K ++ LC K
Sbjct: 694 CFICAVCHVNLEGQPFYSKKDRPLCKK 720
Score = 52.8 bits (125), Expect = 4e-07
Identities = 23/70 (32%), Positives = 30/70 (42%)
Query: 162 CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 221
C CN I + + WH + F C C LA F ++ YC CY+ F A C
Sbjct: 551 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 610
Query: 222 AGCKNPITGK 231
A C I G+
Sbjct: 611 AKCNTKIMGE 620
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 95.9 bits (237), Expect = 4e-20
Identities = 60/202 (29%), Positives = 87/202 (43%), Gaps = 15/202 (7%)
Query: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
C +C +P + V K+ +H CF C C LA F K+ + LC R
Sbjct: 39 CHKCGEPCKGEVLRVQTKH--FHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGT 96
Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC----- 153
+C GC + + + V G +H +CF C+ CK+ G G D C C
Sbjct: 97 RCHGCGEFVEG--EVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154
Query: 154 ---HETKFAKHCVKCNKAITSG-GITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
ET F+ +C C + I +G + D+ WH CF C +C K L G+ + + + YC
Sbjct: 155 SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYC 213
Query: 210 VDCYKNFVAKKCAGCKNPITGK 231
Y+ KC C ITGK
Sbjct: 214 EKDYQGLFGVKCEACHQFITGK 235
Score = 77.0 bits (188), Expect = 2e-14
Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 22/214 (10%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C L + K+G + C + + C C + + + + V + +H
Sbjct: 63 FTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFV--EGEVVTALGKTYHPN 120
Query: 65 CFRCAKCLHPLA---NETFVAKDNKILCNKCTT-REDSPK-------CKGCFKAIVAGDQ 113
CF C C P TF +D LC C SPK C GC + I G Q
Sbjct: 121 CFACTICKRPFPPGDRVTFNGRD--CLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNG-Q 177
Query: 114 NVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG 173
+ WH CF C +C +V+ TG + K YC ++ F C C++ IT
Sbjct: 178 ALLALDKQWHLGCFKCKSCGKVL-TGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKV 236
Query: 174 ITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
+ D+ +H C C C+ Q FT E+ Y
Sbjct: 237 LEAGDKHYHPSCARCSRCN-----QMFTEGEEMY 265
Score = 54.3 bits (129), Expect = 1e-07
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 23/151 (15%)
Query: 87 ILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGE 146
I C+KC CKG + + + +H CFTC C + G FF K
Sbjct: 37 IHCHKC-----GEPCKG---------EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNG 82
Query: 147 DFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKL-AGQRFTAVED 205
++ C ++ + C C + + +T + +H +CF C C + G R T
Sbjct: 83 EYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGR 142
Query: 206 QYYCVDC--------YKNFVAKKCAGCKNPI 228
C C + + CAGC I
Sbjct: 143 DCLCQLCAQPMSSSPKETTFSSNCAGCGRDI 173
Score = 45.1 bits (105), Expect = 9e-05
Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 2/82 (2%)
Query: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
HC KC + + Q + +H CF C C LA F +Y C Y+ +
Sbjct: 38 HCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 97
Query: 221 CAGCKNPITGK--RTVSRVSHP 240
C GC + G+ + + HP
Sbjct: 98 CHGCGEFVEGEVVTALGKTYHP 119
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/180 (21%), Positives = 63/180 (35%), Gaps = 37/180 (20%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHC-CLKCFDKFCAN--------TCVECRKPIGADSKEVH 55
F C C+ P V +G C C C ++ C C + I + + +
Sbjct: 122 FACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDI-KNGQALL 180
Query: 56 YKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCF-----KAIVA 110
++ WH CF+C C L E +++KD C K KC+ C K + A
Sbjct: 181 ALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEA 239
Query: 111 GDQNVEYK---------------------GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 149
GD++ TVWH DC + ++ + + DF+
Sbjct: 240 GDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRLPNIRRSSSDFF 299
>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
Length = 718
Score = 95.9 bits (237), Expect = 4e-20
Identities = 60/202 (29%), Positives = 87/202 (43%), Gaps = 15/202 (7%)
Query: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
C +C +P + V K+ +H CF C C LA F K+ + LC R
Sbjct: 39 CHKCGEPCKGEVLRVQTKH--FHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGT 96
Query: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFP-KGEDFYCVTC----- 153
+C GC + + + V G +H +CF C+ CK+ G G D C C
Sbjct: 97 RCHGCGEFVEG--EVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154
Query: 154 ---HETKFAKHCVKCNKAITSG-GITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
ET F+ +C C + I +G + D+ WH CF C +C K L G+ + + + YC
Sbjct: 155 SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYC 213
Query: 210 VDCYKNFVAKKCAGCKNPITGK 231
Y+ KC C ITGK
Sbjct: 214 EKDYQGLFGVKCEACHQFITGK 235
Score = 77.0 bits (188), Expect = 2e-14
Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 22/214 (10%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
F C C L + K+G + C + + C C + + + + V + +H
Sbjct: 63 FTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFV--EGEVVTALGKTYHPN 120
Query: 65 CFRCAKCLHPLA---NETFVAKDNKILCNKCTT-REDSPK-------CKGCFKAIVAGDQ 113
CF C C P TF +D LC C SPK C GC + I G Q
Sbjct: 121 CFACTICKRPFPPGDRVTFNGRD--CLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNG-Q 177
Query: 114 NVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG 173
+ WH CF C +C +V+ TG + K YC ++ F C C++ IT
Sbjct: 178 ALLALDKQWHLGCFKCKSCGKVL-TGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKV 236
Query: 174 ITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQY 207
+ D+ +H C C C+ Q FT E+ Y
Sbjct: 237 LEAGDKHYHPSCARCSRCN-----QMFTEGEEMY 265
Score = 54.3 bits (129), Expect = 1e-07
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 23/151 (15%)
Query: 87 ILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGE 146
I C+KC CKG + + + +H CFTC C + G FF K
Sbjct: 37 IHCHKC-----GEPCKG---------EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNG 82
Query: 147 DFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKL-AGQRFTAVED 205
++ C ++ + C C + + +T + +H +CF C C + G R T
Sbjct: 83 EYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGR 142
Query: 206 QYYCVDC--------YKNFVAKKCAGCKNPI 228
C C + + CAGC I
Sbjct: 143 DCLCQLCAQPMSSSPKETTFSSNCAGCGRDI 173
Score = 45.1 bits (105), Expect = 9e-05
Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 2/82 (2%)
Query: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220
HC KC + + Q + +H CF C C LA F +Y C Y+ +
Sbjct: 38 HCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 97
Query: 221 CAGCKNPITGK--RTVSRVSHP 240
C GC + G+ + + HP
Sbjct: 98 CHGCGEFVEGEVVTALGKTYHP 119
Score = 42.7 bits (99), Expect = 4e-04
Identities = 37/157 (23%), Positives = 55/157 (35%), Gaps = 37/157 (23%)
Query: 5 FDCHYCRDPLQGKKYVQKDGHHC-CLKCFDKFCAN--------TCVECRKPIGADSKEVH 55
F C C+ P V +G C C C ++ C C + I + + +
Sbjct: 122 FACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDI-KNGQALL 180
Query: 56 YKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCF-----KAIVA 110
++ WH CF+C C L E +++KD C K KC+ C K + A
Sbjct: 181 ALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEA 239
Query: 111 GDQNVEYK---------------------GTVWHKDC 126
GD++ TVWH DC
Sbjct: 240 GDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDC 276
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.481
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,838,767
Number of Sequences: 37866
Number of extensions: 773015
Number of successful extensions: 6842
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 594
Number of HSP's that attempted gapping in prelim test: 2945
Number of HSP's gapped (non-prelim): 2367
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.